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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for BX548005.1+smarcc2
Z-value: 2.50
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Transcription factors associated with BX548005.1+smarcc2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSDARG00000077946 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | |
| ENSDARG00000110907 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| smarcc2 | dr11_v1_chr6_+_39836474_39836474 | 0.53 | 3.2e-08 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_5774977 Show fit | 22.76 |
ENSDART00000134202
|
cholecystokinin a |
|
| chr10_+_36037977 Show fit | 22.67 |
ENSDART00000164678
|
katanin p60 subunit A-like 1 |
|
| chr13_+_33055548 Show fit | 21.55 |
ENSDART00000137315
|
retinol dehydrogenase 12 (all-trans/9-cis/11-cis) |
|
| chr2_-_13254821 Show fit | 19.53 |
ENSDART00000022621
|
3-ketodihydrosphingosine reductase |
|
| chr19_-_5254699 Show fit | 18.71 |
ENSDART00000081951
|
syntaxin 1B |
|
| chr24_-_5932982 Show fit | 18.26 |
ENSDART00000138412
ENSDART00000135124 ENSDART00000007373 |
acyl-CoA binding domain containing 5a |
|
| chr9_+_38481780 Show fit | 17.44 |
ENSDART00000087241
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
|
| chr2_-_13254594 Show fit | 16.59 |
ENSDART00000155671
|
3-ketodihydrosphingosine reductase |
|
| chr5_+_65536095 Show fit | 16.44 |
ENSDART00000189898
|
si:dkey-21e5.1 |
|
| chr15_-_29556757 Show fit | 16.13 |
ENSDART00000060049
|
heat shock protein 70 family, member 13 |
Network of associatons between targets according to the STRING database.
First level regulatory network of BX548005.1+smarcc2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.0 | 36.1 | GO:0030220 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
| 0.6 | 27.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.5 | 24.5 | GO:0032456 | endocytic recycling(GO:0032456) |
| 2.8 | 22.7 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.4 | 22.2 | GO:0016575 | histone deacetylation(GO:0016575) |
| 3.7 | 21.9 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 6.7 | 20.2 | GO:0015889 | cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889) |
| 0.7 | 20.0 | GO:0016114 | terpenoid biosynthetic process(GO:0016114) |
| 1.3 | 19.6 | GO:0042026 | protein refolding(GO:0042026) |
| 0.1 | 18.8 | GO:0000377 | RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 55.5 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 31.5 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.3 | 29.5 | GO:0000922 | spindle pole(GO:0000922) |
| 0.1 | 28.0 | GO:0030424 | axon(GO:0030424) |
| 0.1 | 27.0 | GO:0043005 | neuron projection(GO:0043005) |
| 0.4 | 26.7 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.2 | 26.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.3 | 25.1 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 1.4 | 25.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 23.1 | GO:0005681 | spliceosomal complex(GO:0005681) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 43.4 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.1 | 35.6 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.5 | 34.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.6 | 23.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 2.1 | 22.7 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.4 | 22.2 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 4.4 | 21.9 | GO:0008430 | selenium binding(GO:0008430) |
| 2.5 | 20.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 1.3 | 19.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.7 | 18.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 21.6 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.8 | 16.0 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 6.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 5.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 4.7 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.5 | 4.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.1 | 4.3 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 4.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 3.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.2 | 3.5 | PID IFNG PATHWAY | IFN-gamma pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 36.1 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 1.1 | 18.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.7 | 17.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.5 | 15.5 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.2 | 13.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.5 | 11.0 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.8 | 10.7 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 10.5 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.4 | 9.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 9.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |