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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for CABZ01066694.1
Z-value: 0.85
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Transcription factors associated with CABZ01066694.1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CABZ01066694.1 | dr11_v1_chr6_+_168962_168962 | 0.24 | 1.9e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr23_-_5685023 Show fit | 14.44 |
ENSDART00000148680
ENSDART00000149365 |
troponin T type 2a (cardiac) |
|
| chr12_-_20373058 Show fit | 9.81 |
ENSDART00000066382
|
aquaporin 8a, tandem duplicate 1 |
|
| chr21_-_25756119 Show fit | 6.60 |
ENSDART00000002341
|
claudin c |
|
| chr12_+_18524953 Show fit | 5.95 |
ENSDART00000090332
|
neuralized E3 ubiquitin protein ligase 2 |
|
| chr15_+_32711663 Show fit | 5.91 |
ENSDART00000157854
ENSDART00000167515 |
periostin, osteoblast specific factor b |
|
| chr3_-_20091964 Show fit | 5.86 |
ENSDART00000029386
ENSDART00000020253 ENSDART00000124326 |
solute carrier family 4 (anion exchanger), member 1a (Diego blood group) |
|
| chr10_-_17484762 Show fit | 5.19 |
ENSDART00000137905
ENSDART00000007961 |
5'-nucleotidase, cytosolic II, like 1 |
|
| chr20_+_33981946 Show fit | 4.90 |
ENSDART00000131775
|
si:dkey-51e6.1 |
|
| chr18_-_21188768 Show fit | 4.61 |
ENSDART00000060166
|
glutamic-oxaloacetic transaminase 2a, mitochondrial |
|
| chr7_+_34305903 Show fit | 4.56 |
ENSDART00000173575
|
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CABZ01066694.1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 14.4 | GO:0003228 | atrial cardiac muscle tissue development(GO:0003228) |
| 0.0 | 9.9 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.4 | 7.3 | GO:0016203 | muscle attachment(GO:0016203) |
| 0.4 | 6.6 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.1 | 6.1 | GO:0097696 | JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696) |
| 0.3 | 5.9 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 5.5 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
| 1.6 | 4.9 | GO:0035971 | peptidyl-histidine dephosphorylation(GO:0035971) |
| 1.2 | 4.6 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 0.7 | 4.6 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 14.4 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 8.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 5.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.3 | 4.2 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 4.1 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 4.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.5 | 3.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.1 | 3.3 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 2.6 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 2.6 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 14.4 | GO:0030172 | troponin C binding(GO:0030172) troponin I binding(GO:0031013) |
| 0.0 | 9.9 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 1.1 | 9.8 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 6.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.3 | 5.9 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 0.2 | 5.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 1.2 | 4.9 | GO:0101006 | protein histidine phosphatase activity(GO:0101006) |
| 1.5 | 4.6 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 1.2 | 4.6 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.0 | 4.5 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.1 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 4.3 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 3.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 1.7 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 1.5 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 1.4 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.0 | 0.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 0.8 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.3 | 4.5 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 4.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.5 | 3.9 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 2.8 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 1.7 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.2 | 1.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.5 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 1.4 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.2 | REACTOME SIGNALING BY ERBB4 | Genes involved in Signaling by ERBB4 |