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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 0.95

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Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Gene Symbol Gene ID Gene Info
ENSDARG00000107408 transcription factor 4
ENSDARG00000045131 inhibitor of DNA binding 4
ENSDARG00000017078 mesoderm posterior aa
ENSDARG00000030347 mesoderm posterior ba
ENSDARG00000068761 mesoderm posterior ab
ENSDARG00000097947 mesoderm posterior bb
ENSDARG00000110553 mesoderm posterior ba
ENSDARG00000114890 mesoderm posterior aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
id4dr11_v1_chr16_-_9980402_9980402-0.423.1e-05Click!
TCF4dr11_v1_chr21_+_1382078_1382078-0.303.3e-03Click!
mespaadr11_v1_chr7_+_15308042_15308042-0.223.7e-02Click!
mespabdr11_v1_chr25_-_11016675_11016675-0.196.4e-02Click!
mespbadr11_v1_chr7_+_15313443_153134430.084.5e-01Click!
mespbbdr11_v1_chr25_-_11026907_11026907-0.056.0e-01Click!

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_36834505 11.39 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr19_-_48312109 11.29 ENSDART00000161103
si:ch73-359m17.9
chr20_-_42702832 10.08 ENSDART00000134689
ENSDART00000045816
plasminogen
chr2_-_47620806 7.95 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr3_+_42923275 7.47 ENSDART00000168228
transmembrane protein 184a
chr2_-_22688651 7.20 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr16_+_52512025 6.83 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr6_+_29305190 5.46 ENSDART00000078647
si:ch211-201h21.5
chr13_-_21672131 5.19 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr6_-_40058686 5.08 ENSDART00000103240
urocanate hydratase 1
chr22_+_661711 5.04 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_+_58751504 4.95 ENSDART00000024185
zgc:56231
chr12_-_23365737 4.92 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr9_-_34269066 4.81 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr15_-_43164591 4.70 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr4_+_72797711 4.63 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr14_+_11458044 4.62 ENSDART00000186425
si:ch211-153b23.5
chr22_+_7439476 4.45 ENSDART00000021594
ENSDART00000063389
zgc:92041
chr25_-_4146947 4.44 ENSDART00000129268
fatty acid desaturase 2
chr8_+_15254564 4.37 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr22_+_661505 4.31 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr25_-_32311048 4.28 ENSDART00000181806
ENSDART00000086334

chr22_-_17677947 4.21 ENSDART00000139911
tight junction protein 3
chr2_-_41942666 4.14 ENSDART00000075673
Epstein-Barr virus induced 3
chr21_-_34261677 4.01 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr5_-_6567464 3.99 ENSDART00000184985
tankyrase 1 binding protein 1
chr21_-_30293224 3.94 ENSDART00000101051
stem-loop binding protein 2
chr14_+_11457500 3.90 ENSDART00000169202
si:ch211-153b23.5
chr4_-_9549693 3.89 ENSDART00000160242

chr15_+_20239141 3.83 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr21_-_25756119 3.80 ENSDART00000002341
claudin c
chr6_+_45918981 3.77 ENSDART00000149642
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_+_7358749 3.76 ENSDART00000081660
Indian hedgehog homolog a
chr6_+_10333920 3.73 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr6_+_42338309 3.72 ENSDART00000015277
glutathione peroxidase 1b
chr7_+_7048245 3.71 ENSDART00000001649
actinin alpha 3b
chr5_-_38451082 3.64 ENSDART00000136428
cholinergic receptor, nicotinic, epsilon
chr21_-_26114886 3.64 ENSDART00000139320
NIPA-like domain containing 4
chr7_+_61184551 3.57 ENSDART00000190788
zgc:194930
chr3_+_62161184 3.57 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr25_-_3867990 3.54 ENSDART00000075663
calcium release activated channel regulator 2B
chr12_+_46543572 3.51 ENSDART00000167510
HID1 domain containing b
chr1_-_18811517 3.48 ENSDART00000142026
si:dkey-167i21.2
chr6_-_609880 3.46 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr21_-_43666420 3.44 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr14_-_33277743 3.44 ENSDART00000048130
START domain containing 14
chr23_-_31266586 3.43 ENSDART00000139746
si:dkey-261l7.2
chr22_-_25612680 3.41 ENSDART00000114167
si:ch211-12h2.8
chr21_-_40630650 3.39 ENSDART00000172706
phosphate cytidylyltransferase 1, choline, beta b
chr10_+_3520256 3.35 ENSDART00000003242
zgc:123275
chr17_+_53294228 3.34 ENSDART00000158172
si:ch1073-416d2.3
chr16_-_17713859 3.34 ENSDART00000149275
zgc:174935
chr13_-_34683370 3.33 ENSDART00000113661
kinesin family member 16Bb
chr11_+_329687 3.30 ENSDART00000172882
cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_+_9191981 3.27 ENSDART00000150916
zgc:112392
chr9_+_310331 3.23 ENSDART00000172446
ENSDART00000187731
ENSDART00000193970
SH3 and cysteine rich domain 3
chr21_-_39024754 3.22 ENSDART00000056878
tnf receptor-associated factor 4b
chr5_-_69948099 3.17 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr10_-_25217347 3.16 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr7_-_38644560 3.15 ENSDART00000114934
six-cysteine containing astacin protease 3
chr24_-_25244637 3.12 ENSDART00000153798
HERV-H LTR-associating 2b, tandem duplicate 2
chr1_-_12027 3.12 ENSDART00000164359
ribosomal protein L24
chr7_+_39446247 3.07 ENSDART00000033610
ENSDART00000099015
troponin T type 3b (skeletal, fast)
chr17_-_30473374 2.97 ENSDART00000155021
si:ch211-175f11.5
chr12_+_6041575 2.97 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr7_-_53117131 2.96 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr7_+_57088920 2.94 ENSDART00000024076
secretory carrier membrane protein 2, like
chr13_-_12581388 2.93 ENSDART00000079655
glutamyl aminopeptidase
chr11_-_37995501 2.87 ENSDART00000192096
solute carrier family 41 (magnesium transporter), member 1
chr19_+_2590182 2.86 ENSDART00000162293
si:ch73-345f18.3
chr16_+_46695777 2.84 ENSDART00000169767
RAB25, member RAS oncogene family b
chr3_-_26204867 2.82 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr2_-_24402341 2.81 ENSDART00000155442
ENSDART00000088572
zgc:154006
chr1_+_30422143 2.81 ENSDART00000033024
transmembrane protein 41ab
chr22_+_11756040 2.80 ENSDART00000105808
keratin 97
chr16_-_42066523 2.80 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr20_+_10538025 2.79 ENSDART00000129762
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr7_-_38644287 2.77 ENSDART00000182307
six-cysteine containing astacin protease 3
chr21_-_25741411 2.73 ENSDART00000101211
claudin h
chr25_-_13614863 2.73 ENSDART00000121859
fatty acid 2-hydroxylase
chr24_-_25691020 2.72 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr18_+_45666489 2.69 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr7_+_30392613 2.63 ENSDART00000075508
lipase, hepatic a
chr5_-_23696926 2.63 ENSDART00000021462
ring finger protein 128a
chr23_-_29556844 2.59 ENSDART00000138021
retinol binding protein 7a, cellular
chr19_+_48117995 2.59 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr10_-_2942900 2.59 ENSDART00000002622
occludin a
chr6_+_6780873 2.58 ENSDART00000011865
Sec23 homolog B, COPII coat complex component
chr14_-_46198373 2.57 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr14_+_15155684 2.55 ENSDART00000167966
zgc:158852
chr14_-_33278084 2.53 ENSDART00000132850
START domain containing 14
chr9_+_307863 2.52 ENSDART00000163474
SH3 and cysteine rich domain 3
chr17_+_30894431 2.50 ENSDART00000127996
delta(4)-desaturase, sphingolipid 2
chr3_+_36424055 2.49 ENSDART00000170318
si:ch1073-443f11.2
chr23_+_39854566 2.48 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr23_+_553396 2.44 ENSDART00000034707
LSM family member 14B
chr6_-_13498745 2.43 ENSDART00000027684
ENSDART00000189438
myosin light chain kinase b
chr12_-_28818720 2.43 ENSDART00000134453
ENSDART00000141727
proline rich 15-like b
chr3_+_14388010 2.42 ENSDART00000171726
ENSDART00000165452
transmembrane protein 56b
chr5_-_32338866 2.41 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr25_-_17587785 2.40 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr11_-_34097418 2.38 ENSDART00000028301
ENSDART00000138579
tryptophan 2,3-dioxygenase b
chr1_-_20593778 2.38 ENSDART00000124770
UDP glycosyltransferase 8
chr20_+_46924390 2.34 ENSDART00000132161
si:ch73-21k16.5
chr22_+_7480465 2.33 ENSDART00000034545
zgc:92745
chr6_-_130849 2.33 ENSDART00000108710
si:zfos-323e3.4
chr7_+_32901658 2.29 ENSDART00000115420
anoctamin 9b
chr15_-_3282220 2.29 ENSDART00000092942
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr4_-_948776 2.29 ENSDART00000023483
single-minded family bHLH transcription factor 1b
chr3_+_25849560 2.28 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr25_+_5249513 2.26 ENSDART00000126814

chr14_-_83154 2.25 ENSDART00000187097

chr25_-_17395315 2.25 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr13_+_50375800 2.25 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr14_-_36862745 2.24 ENSDART00000109293
ring finger protein 130
chr9_-_39005317 2.21 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr15_+_29025090 2.20 ENSDART00000131755
si:ch211-137a8.2
chr1_-_50247 2.19 ENSDART00000168428
immunoglobulin-like domain containing receptor 1a
chr1_-_29747702 2.19 ENSDART00000133225
ENSDART00000189670
secreted phosphoprotein 2
chr11_-_25853212 2.18 ENSDART00000145655
transmembrane protein 51b
chr13_-_41908583 2.16 ENSDART00000136515
inositol polyphosphate multikinase a
chr13_-_50108337 2.16 ENSDART00000133308
nidogen 1a
chr19_-_42551338 2.15 ENSDART00000162837
zgc:123103
chr18_-_502722 2.15 ENSDART00000185757
short chain dehydrogenase/reductase family 42E, member 1
chr10_+_34001444 2.15 ENSDART00000149934
klotho
chr19_+_7636941 2.14 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr2_+_6253246 2.14 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr22_+_7439186 2.10 ENSDART00000190667
zgc:92041
chr16_+_34111919 2.10 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
transcription elongation factor A (SII), 3
chr1_+_24387659 2.06 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr14_+_32964 2.04 ENSDART00000166173
Ly1 antibody reactive homolog (mouse)
chr11_-_165288 2.04 ENSDART00000108703
ENSDART00000173151
testis enhanced gene transcript (BAX inhibitor 1)
chr17_-_25331439 2.03 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr3_+_14641962 2.03 ENSDART00000091070
zgc:158403
chr7_+_6969909 2.02 ENSDART00000189886
actinin alpha 3b
chr23_+_44881020 2.00 ENSDART00000149355
si:ch73-361h17.1
chr8_-_47844456 1.99 ENSDART00000145429
si:dkeyp-104h9.5
chr24_+_35564668 1.99 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr3_+_32526799 1.99 ENSDART00000185755
si:ch73-367p23.2
chr17_-_52595932 1.95 ENSDART00000127225
si:ch211-173a9.7
chr9_-_16109001 1.95 ENSDART00000053473
uridine phosphorylase 2
chr2_+_17181777 1.95 ENSDART00000112063
prostaglandin E receptor 4 (subtype EP4) c
chr17_-_5878032 1.94 ENSDART00000148916
glucokinase (hexokinase 4) regulator
chr16_+_46725087 1.94 ENSDART00000008920
RAB11a, member RAS oncogene family, like
chr2_+_11031360 1.93 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr22_-_10541372 1.93 ENSDART00000179708
si:dkey-42i9.4
chr16_+_23975930 1.92 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apolipoprotein C-IV
chr17_-_36860988 1.92 ENSDART00000154981
SUMO1/sentrin specific peptidase 6b
chr6_+_153146 1.91 ENSDART00000097468
zinc finger, GATA-like protein 1
chr25_+_7492663 1.89 ENSDART00000166496
catalase
chr8_+_29593986 1.88 ENSDART00000077642
atonal bHLH transcription factor 1a
chr21_-_25741096 1.88 ENSDART00000181756
claudin h
chr21_-_19919020 1.88 ENSDART00000147396
protein phosphatase 1, regulatory subunit 3B
chr17_+_39242437 1.86 ENSDART00000156138
ENSDART00000128863
zgc:174356
chr16_-_25608453 1.85 ENSDART00000140140
zgc:110410
chr12_+_13091842 1.85 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr5_-_25723079 1.84 ENSDART00000014013
guanine deaminase
chr2_+_27855346 1.84 ENSDART00000175159
ENSDART00000192645
bucky ball
chr5_-_69212184 1.83 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr12_+_19401854 1.83 ENSDART00000153415
si:dkey-16i5.8
chr10_+_29771256 1.82 ENSDART00000193195
hypoxia up-regulated 1
chr15_-_3277635 1.82 ENSDART00000189094
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr10_+_38775408 1.82 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr21_-_7928101 1.82 ENSDART00000151543
ENSDART00000114982
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr19_-_27339670 1.82 ENSDART00000139323
zinc ribbon domain containing 1
chr17_-_5610514 1.81 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr15_+_43906043 1.81 ENSDART00000010881
N-acetylated alpha-linked acidic dipeptidase 2
chr10_-_2943474 1.81 ENSDART00000188698
occludin a
chr17_+_51906053 1.80 ENSDART00000159072
ENSDART00000056869
feline leukemia virus subgroup C cellular receptor family, member 2a
chr12_-_48312647 1.79 ENSDART00000114415
activating signal cointegrator 1 complex subunit 1
chr13_+_33606739 1.79 ENSDART00000026464
cofilin 1 (non-muscle), like
chr21_-_20725853 1.79 ENSDART00000114502
si:ch211-22d5.2
chr22_+_11775269 1.79 ENSDART00000140272
keratin 96
chr23_+_26733232 1.78 ENSDART00000035080
zgc:158263
chr22_-_10110959 1.76 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr3_-_40275096 1.75 ENSDART00000141578
serine hydroxymethyltransferase 1 (soluble)
chr24_-_24983047 1.74 ENSDART00000066631
solute carrier family 51, alpha subunit
chr7_-_55648336 1.73 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr10_-_1961930 1.73 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr8_+_6576940 1.73 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr2_-_50225411 1.71 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr22_+_34710036 1.71 ENSDART00000025820
4-hydroxy-2-oxoglutarate aldolase 1
chr2_-_43698531 1.71 ENSDART00000170968

chr17_+_53292215 1.70 ENSDART00000170686
si:ch1073-416d2.3
chr20_-_21672970 1.70 ENSDART00000133286
si:ch211-207i1.2
chr2_-_58075414 1.69 ENSDART00000161920
nectin cell adhesion molecule 4
chr21_+_38817785 1.69 ENSDART00000177616
ENSDART00000149085
HNF1 homeobox Bb
chr16_+_23976227 1.69 ENSDART00000193013
apolipoprotein C-IV
chr21_-_22543611 1.69 ENSDART00000177084
myosin VB
chr23_+_9867483 1.67 ENSDART00000023099
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr19_+_791538 1.67 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr15_-_33964897 1.66 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lipolysis stimulated lipoprotein receptor
chr24_+_10898671 1.65 ENSDART00000106272
si:dkey-37o8.1
chr5_-_23715861 1.65 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr7_+_61184104 1.65 ENSDART00000110671
zgc:194930
chr10_+_38775959 1.64 ENSDART00000192990
Down syndrome cell adhesion molecule a
chr2_-_37280617 1.64 ENSDART00000190458
NAD kinase b
chr11_-_28050559 1.64 ENSDART00000136859
endothelin converting enzyme 1
chr7_+_14005111 1.63 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr3_-_61494840 1.63 ENSDART00000101957
BAI1-associated protein 2-like 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0042730 fibrinolysis(GO:0042730)
1.7 5.1 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.5 9.0 GO:0006545 glycine biosynthetic process(GO:0006545)
1.4 4.1 GO:0044321 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
1.4 4.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
1.2 5.8 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
1.0 3.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.0 3.1 GO:0090008 hypoblast development(GO:0090008)
0.8 3.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.7 12.5 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7 4.6 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.6 1.9 GO:0009750 response to fructose(GO:0009750)
0.6 4.5 GO:0040016 embryonic cleavage(GO:0040016)
0.6 1.9 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 1.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 3.7 GO:0010269 response to selenium ion(GO:0010269)
0.6 1.8 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.6 1.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.6 1.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.6 3.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.5 3.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.5 1.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.5 1.5 GO:0030237 female sex determination(GO:0030237)
0.5 2.5 GO:0043420 anthranilate metabolic process(GO:0043420)
0.5 2.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.5 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.5 1.9 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.5 1.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 2.7 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.5 1.8 GO:0097037 heme export(GO:0097037)
0.4 4.4 GO:0030104 water homeostasis(GO:0030104)
0.4 1.7 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 4.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4 2.4 GO:0046218 tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.4 1.9 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.4 1.5 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.4 2.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.4 0.7 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.3 1.4 GO:0042755 eating behavior(GO:0042755)
0.3 3.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 3.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.3 3.0 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3 2.4 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.3 1.2 GO:0042985 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.3 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 1.5 GO:0070986 left/right axis specification(GO:0070986)
0.3 1.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 2.9 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.3 1.7 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3 1.7 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.3 4.2 GO:0015693 magnesium ion transport(GO:0015693)
0.3 4.8 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.3 0.8 GO:0065001 specification of axis polarity(GO:0065001)
0.3 3.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 1.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 4.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.3 1.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.3 2.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 3.8 GO:0016486 peptide hormone processing(GO:0016486)
0.2 2.7 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.2 0.7 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.2 0.7 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2 1.0 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.2 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 3.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 2.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 0.7 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 2.5 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 1.5 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 1.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.2 0.4 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.2 1.9 GO:0010138 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.2 0.8 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.2 1.5 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 2.5 GO:0034311 diol metabolic process(GO:0034311)
0.2 0.7 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.2 1.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.2 0.7 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.2 0.7 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2 2.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 1.0 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.2 2.0 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.2 0.3 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.2 0.7 GO:0006844 acyl carnitine transport(GO:0006844)
0.2 1.0 GO:0006004 fucose metabolic process(GO:0006004)
0.2 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.8 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 0.5 GO:0002369 T cell cytokine production(GO:0002369)
0.2 3.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.5 GO:2000648 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.2 0.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 1.2 GO:0042554 superoxide anion generation(GO:0042554)
0.2 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.4 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.1 GO:0060017 parathyroid gland development(GO:0060017)
0.1 3.0 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.7 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.8 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 3.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.6 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.6 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 1.2 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.9 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 5.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.9 GO:0032196 transposition(GO:0032196)
0.1 0.7 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.4 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 3.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.5 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 0.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.8 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.6 GO:0019359 NAD biosynthetic process(GO:0009435) nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
0.1 2.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.4 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.7 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1 1.5 GO:0016556 mRNA modification(GO:0016556)
0.1 0.5 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 1.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 4.5 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 1.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.9 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.3 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.1 1.7 GO:0061055 myotome development(GO:0061055)
0.1 0.3 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 2.7 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.1 2.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.3 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.4 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.6 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 1.1 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.1 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.4 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.4 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.1 0.9 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 0.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.7 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.6 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 2.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867) positive regulation of triglyceride metabolic process(GO:0090208)
0.1 4.4 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 1.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.3 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.2 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
0.1 0.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.2 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 0.2 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 6.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.0 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 0.5 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.5 GO:0044209 AMP salvage(GO:0044209)
0.1 0.5 GO:0035627 ceramide transport(GO:0035627)
0.1 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 4.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.1 5.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 4.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.1 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 3.5 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0070293 renal absorption(GO:0070293)
0.1 0.9 GO:0001840 neural plate development(GO:0001840)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 2.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 8.1 GO:0045765 regulation of angiogenesis(GO:0045765)
0.1 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.3 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 1.9 GO:0007568 aging(GO:0007568)
0.1 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 1.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.7 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 1.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 4.0 GO:0006414 translational elongation(GO:0006414)
0.1 1.4 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.1 0.3 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.4 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 0.3 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 2.0 GO:0051346 negative regulation of hydrolase activity(GO:0051346)
0.1 0.2 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:0008585 female gonad development(GO:0008585)
0.1 2.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 1.0 GO:0031297 replication fork processing(GO:0031297)
0.1 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.3 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 2.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0002360 T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) positive T cell selection(GO:0043368) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T cell selection(GO:0045058) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 0.2 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0 0.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.6 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 2.2 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 1.1 GO:0048599 oocyte development(GO:0048599)
0.0 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 1.9 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 1.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.9 GO:0046849 bone remodeling(GO:0046849)
0.0 0.1 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.5 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.3 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.3 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 8.0 GO:0006954 inflammatory response(GO:0006954)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.7 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 1.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.3 GO:0010889 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.9 GO:0003323 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.0 2.1 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.3 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.3 GO:0030282 bone mineralization(GO:0030282)
0.0 1.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 1.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 1.6 GO:0007492 endoderm development(GO:0007492)
0.0 0.1 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0048387 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 3.7 GO:0006364 rRNA processing(GO:0006364)
0.0 0.3 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.9 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.1 GO:0010991 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.7 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.8 GO:0006900 membrane budding(GO:0006900)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.0 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 4.2 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0048538 thymus development(GO:0048538)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.0 0.2 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.6 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.7 GO:0006914 autophagy(GO:0006914)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.5 GO:0010952 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0 0.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.4 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.7 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.1 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0072676 lymphocyte migration(GO:0072676)
0.0 0.7 GO:0007602 phototransduction(GO:0007602)
0.0 0.7 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 12.8 GO:0006508 proteolysis(GO:0006508)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.0 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0000726 non-recombinational repair(GO:0000726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 0.8 GO:0033391 chromatoid body(GO:0033391)
0.7 3.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.6 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 6.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 1.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.4 6.6 GO:0030315 T-tubule(GO:0030315)
0.4 3.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.3 1.3 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.3 5.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 5.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 3.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 1.0 GO:0043073 germ cell nucleus(GO:0043073)
0.2 0.6 GO:0005948 acetolactate synthase complex(GO:0005948)
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.2 20.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 2.9 GO:0030057 desmosome(GO:0030057)
0.2 0.5 GO:0098536 deuterosome(GO:0098536)
0.2 1.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 8.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614)
0.1 2.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 9.2 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.6 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.3 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.4 GO:0032433 filopodium tip(GO:0032433)
0.1 9.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 4.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.4 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.9 GO:0036157 outer dynein arm(GO:0036157)
0.1 4.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.6 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 5.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.9 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.5 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 5.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.3 GO:0055037 recycling endosome(GO:0055037)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 8.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 10.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.2 GO:0010008 endosome membrane(GO:0010008)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0030662 coated vesicle membrane(GO:0030662)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 10.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 1.9 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 17.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
1.3 3.9 GO:0034185 apolipoprotein binding(GO:0034185)
1.3 11.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.3 3.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.2 7.4 GO:0032052 bile acid binding(GO:0032052)
0.8 2.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.8 3.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.7 12.5 GO:0032190 acrosin binding(GO:0032190)
0.7 4.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.7 2.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 1.8 GO:0001729 ceramide kinase activity(GO:0001729)
0.6 1.8 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.6 2.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6 4.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.5 4.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.5 4.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5 4.4 GO:0005113 patched binding(GO:0005113)
0.5 2.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.5 1.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.4 1.2 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.3 1.7 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 1.0 GO:0042806 fucose binding(GO:0042806)
0.3 4.3 GO:0070697 activin receptor binding(GO:0070697)
0.3 3.2 GO:0016936 galactoside binding(GO:0016936)
0.3 2.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 2.9 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.3 1.5 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 1.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 1.2 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.3 2.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 7.9 GO:0008483 transaminase activity(GO:0008483)
0.3 0.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3 2.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 6.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 1.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 0.8 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 1.9 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 2.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.8 GO:0015232 heme transporter activity(GO:0015232)
0.2 4.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.9 GO:0004096 catalase activity(GO:0004096)
0.2 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.0 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2 1.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 1.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 3.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 0.6 GO:0003984 acetolactate synthase activity(GO:0003984)
0.2 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 2.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.9 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 0.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.2 1.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 0.7 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.2 3.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 3.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.9 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 2.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.2 0.6 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.2 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 2.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.7 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 3.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.9 GO:2001069 glycogen binding(GO:2001069)
0.1 5.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 12.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.1 3.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 3.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.8 GO:1903924 estradiol binding(GO:1903924)
0.1 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.5 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 3.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.3 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.4 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 6.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.5 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 4.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 17.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 5.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.3 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 2.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 4.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 3.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.4 GO:0019843 rRNA binding(GO:0019843)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:1990174 m7G(5')pppN diphosphatase activity(GO:0050072) phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 1.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.2 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 4.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 2.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 7.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 10.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 2.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0004549 ribonuclease P activity(GO:0004526) tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.5 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 1.8 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 6.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.4 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.4 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.5 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0002020 protease binding(GO:0002020)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.4 GO:0042562 hormone binding(GO:0042562)
0.0 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 3.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 1.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 1.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.7 GO:0032934 sterol binding(GO:0032934)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 4.7 PID IL27 PATHWAY IL27-mediated signaling events
0.2 0.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 4.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 3.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.7 PID BMP PATHWAY BMP receptor signaling
0.1 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.9 PID FOXO PATHWAY FoxO family signaling
0.1 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
1.0 3.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7 3.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.7 6.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6 1.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 4.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.4 2.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 1.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 4.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 1.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 5.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 2.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 9.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 4.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination