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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for VDR+nr1i2_vdrb

Z-value: 0.65

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Transcription factors associated with VDR+nr1i2_vdrb

Gene Symbol Gene ID Gene Info
nr1i2
ENSDARG00000029766 nuclear receptor subfamily 1, group I, member 2
VDR
ENSDARG00000112923 vitamin D receptor
vdrb
ENSDARG00000070721 vitamin D receptor b
vdrb
ENSDARG00000114864 vitamin D receptor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
vdrbdr11_v1_chr6_-_39005133_39005133-0.223.7e-02Click!
CABZ01088036.1dr11_v1_chr23_+_45785563_45785563-0.161.2e-01Click!
nr1i2dr11_v1_chr9_+_9502610_9502610-0.122.5e-01Click!

Activity profile of VDR+nr1i2_vdrb motif

Sorted Z-values of VDR+nr1i2_vdrb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_-_4148719 17.00 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr8_+_1769475 4.30 ENSDART00000079073
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_+_10134345 4.17 ENSDART00000100725
ahsg2
alpha-2-HS-glycoprotein 2
chr1_-_25679339 3.97 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr14_-_21063977 3.88 ENSDART00000164373
si:dkey-74k8.3
si:dkey-74k8.3
chr23_-_44723102 3.87 ENSDART00000129138
mogat3a
monoacylglycerol O-acyltransferase 3a
chr14_-_21064199 3.84 ENSDART00000172099
si:dkey-74k8.3
si:dkey-74k8.3
chr3_+_46425262 3.13 ENSDART00000153690
sc:d0202
sc:d0202
chr3_+_12744083 3.09 ENSDART00000158554
ENSDART00000169545
cyp2k21
cytochrome P450, family 2, subfamily k, polypeptide 21
chr20_+_17581881 2.97 ENSDART00000182832
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr25_+_13191391 2.66 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr6_-_13498745 2.47 ENSDART00000027684
ENSDART00000189438
mylkb
myosin light chain kinase b
chr3_-_32912787 2.41 ENSDART00000156149
g6pcb
glucose-6-phosphatase b, catalytic subunit
chr21_-_25756119 2.32 ENSDART00000002341
cldnc
claudin c
chr7_+_52122224 2.23 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr6_+_9893554 2.16 ENSDART00000064979
pimr74
Pim proto-oncogene, serine/threonine kinase, related 74
chr14_+_22076596 2.14 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr25_+_13191615 2.13 ENSDART00000168849
si:ch211-147m6.2
si:ch211-147m6.2
chr21_-_1012269 1.97 ENSDART00000159835
CABZ01057159.1

chr5_-_42544522 1.84 ENSDART00000157968
BX510949.1

chr10_+_7564106 1.78 ENSDART00000159042
purg
purine-rich element binding protein G
chr7_-_38183331 1.74 ENSDART00000149382
abcc12
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr7_+_46003449 1.71 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
si:ch211-260e23.9
chr25_+_4541211 1.70 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr23_+_42454292 1.67 ENSDART00000171459
cyp2aa2
y cytochrome P450, family 2, subfamily AA, polypeptide 2
chr23_+_44611864 1.67 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr21_+_5589923 1.63 ENSDART00000160885
stbd1
starch binding domain 1
chr6_+_9155271 1.62 ENSDART00000168727
zgc:64065
zgc:64065
chr10_+_7563755 1.55 ENSDART00000165877
purg
purine-rich element binding protein G
chr10_-_373575 1.48 ENSDART00000114487
DMPK
DM1 protein kinase
chr15_+_32297441 1.43 ENSDART00000153657
trim3a
tripartite motif containing 3a
chr21_+_29179887 1.42 ENSDART00000161941
si:ch211-57b15.1
si:ch211-57b15.1
chr12_+_20506197 1.41 ENSDART00000153010
si:zfos-754c12.2
si:zfos-754c12.2
chr9_-_28616436 1.41 ENSDART00000136985
si:ch73-7i4.2
si:ch73-7i4.2
chr2_-_17392799 1.34 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr16_+_16969060 1.34 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr23_-_46040618 1.33 ENSDART00000161415
CABZ01080918.1

chr21_-_19918286 1.32 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr9_-_7378566 1.30 ENSDART00000144003
slc23a3
solute carrier family 23, member 3
chr14_+_8715527 1.28 ENSDART00000170754
kcnk4a
potassium channel, subfamily K, member 4a
chr19_-_20148469 1.28 ENSDART00000134476
si:ch211-155k24.1
si:ch211-155k24.1
chr14_-_41468892 1.24 ENSDART00000173099
ENSDART00000003170
mid1ip1l
MID1 interacting protein 1, like
chr10_-_22803740 1.23 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr2_+_21309272 1.20 ENSDART00000141322
zbtb47a
zinc finger and BTB domain containing 47a
chr7_-_24995631 1.19 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr25_-_13188214 1.12 ENSDART00000187298
si:ch211-147m6.1
si:ch211-147m6.1
chr3_+_52473670 1.11 ENSDART00000154310
si:ch211-191c10.3
si:ch211-191c10.3
chr1_-_23595779 1.06 ENSDART00000134860
ENSDART00000138852
lcorl
ligand dependent nuclear receptor corepressor-like
chr13_+_45332203 1.05 ENSDART00000110466
si:ch211-168h21.3
si:ch211-168h21.3
chr12_-_1557286 1.05 ENSDART00000082110
sstr2a
somatostatin receptor 2a
chr14_-_11430566 1.04 ENSDART00000137154
ENSDART00000091158
irg1l
immunoresponsive gene 1, like
chr24_+_2495197 1.01 ENSDART00000146887
f13a1a.1
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr19_+_2896188 0.98 ENSDART00000151421
si:ch211-251g8.5
si:ch211-251g8.5
chr8_+_23245596 0.96 ENSDART00000143313
si:ch211-196c10.11
si:ch211-196c10.11
chr18_+_7073130 0.93 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr12_+_46608361 0.93 ENSDART00000189164
FADS6
fatty acid desaturase 6
chr16_+_19536614 0.92 ENSDART00000112894
ENSDART00000079201
ENSDART00000139357
sp8b
sp8 transcription factor b
chr17_-_32370047 0.92 ENSDART00000145487
klf11b
Kruppel-like factor 11b
chr3_+_36366577 0.89 ENSDART00000151203
rgs9a
regulator of G protein signaling 9a
chr4_-_11737939 0.88 ENSDART00000150299
podxl
podocalyxin-like
chr3_-_34656745 0.87 ENSDART00000144824
znfl1
zinc finger-like gene 1
chr12_+_18663154 0.84 ENSDART00000057918
si:ch211-147h1.4
si:ch211-147h1.4
chr20_+_34374735 0.84 ENSDART00000144090
si:dkeyp-11g8.3
si:dkeyp-11g8.3
chr20_-_29505863 0.83 ENSDART00000148278
klf11a
Kruppel-like factor 11a
chr15_-_24883956 0.81 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr12_+_2660733 0.81 ENSDART00000152235
irbpl
interphotoreceptor retinoid-binding protein like
chr9_-_31763246 0.81 ENSDART00000114742
si:dkey-250i3.3
si:dkey-250i3.3
chr6_+_50451337 0.79 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr8_+_25295160 0.77 ENSDART00000049793
gstm.1
glutathione S-transferase mu, tandem duplicate 1
chr14_-_11529311 0.72 ENSDART00000127208
si:ch211-153b23.7
si:ch211-153b23.7
chr3_+_32749613 0.70 ENSDART00000053684
hsd3b7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase
chr9_+_15837398 0.68 ENSDART00000141063
si:dkey-103d23.5
si:dkey-103d23.5
chr20_-_40760217 0.67 ENSDART00000101007
cx34.5
connexin 34.5
chr6_+_27624023 0.65 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr4_-_18416566 0.65 ENSDART00000033717
cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr4_-_20177868 0.64 ENSDART00000003621
sinup
siaz-interacting nuclear protein
chr22_-_8720794 0.64 ENSDART00000191236
ENSDART00000185738
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr10_+_42691210 0.64 ENSDART00000193813
rhobtb2b
Rho-related BTB domain containing 2b
chr3_-_25116208 0.64 ENSDART00000183628
chadla
chondroadherin-like a
chr15_+_20543770 0.63 ENSDART00000092357
sgsm2
small G protein signaling modulator 2
chr10_+_15603082 0.63 ENSDART00000024450
zfand5b
zinc finger, AN1-type domain 5b
chr21_-_18972206 0.62 ENSDART00000146743
pimr72
Pim proto-oncogene, serine/threonine kinase, related 72
chr9_+_38888025 0.62 ENSDART00000148306
map2
microtubule-associated protein 2
chr15_+_9053059 0.61 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr7_+_3558512 0.61 ENSDART00000131884
si:dkey-192d15.1
si:dkey-192d15.1
chr23_+_28809002 0.56 ENSDART00000134121
ENSDART00000183661
pex14
peroxisomal biogenesis factor 14
chr6_-_43677125 0.56 ENSDART00000150128
foxp1b
forkhead box P1b
chr10_+_9561066 0.56 ENSDART00000136281
si:ch211-243g18.2
si:ch211-243g18.2
chr15_-_38361787 0.56 ENSDART00000155758
trpc2a
transient receptor potential cation channel, subfamily C, member 2a
chr19_-_32600638 0.55 ENSDART00000143497
zgc:91944
zgc:91944
chr5_+_39875646 0.55 ENSDART00000097608
si:ch73-138i16.1
si:ch73-138i16.1
chr1_+_54626491 0.54 ENSDART00000136063
si:ch211-202h22.9
si:ch211-202h22.9
chr23_+_35672542 0.54 ENSDART00000046268
pmelb
premelanosome protein b
chr8_+_20918207 0.52 ENSDART00000144039
si:ch73-196i15.5
si:ch73-196i15.5
chr23_+_5631381 0.50 ENSDART00000149143
pkp1a
plakophilin 1a
chr8_-_3346692 0.50 ENSDART00000057874
FUT9 (1 of many)
zgc:103510
chrM_+_11299 0.49 ENSDART00000093618
mt-nd4
NADH dehydrogenase 4, mitochondrial
chr18_+_36037223 0.49 ENSDART00000144410
tmem91
transmembrane protein 91
chr12_-_13556536 0.49 ENSDART00000166396
CR354395.1

chr14_+_35383267 0.48 ENSDART00000143818
clint1a
clathrin interactor 1a
chr22_-_30999489 0.48 ENSDART00000139706
ssuh2.3
ssu-2 homolog, tandem duplicate 3
chr14_-_24101897 0.48 ENSDART00000143695
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr19_-_9776075 0.48 ENSDART00000140332
si:dkey-14o18.1
si:dkey-14o18.1
chr14_-_858985 0.47 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr24_-_32563875 0.46 ENSDART00000020982
CR792422.1

chr15_-_8665662 0.45 ENSDART00000090675
arhgap35a
Rho GTPase activating protein 35a
chr11_-_3907937 0.44 ENSDART00000082409
rpn1
ribophorin I
chr8_-_1267247 0.43 ENSDART00000150064
cdc14b
cell division cycle 14B
chr16_+_5539189 0.42 ENSDART00000178106
CR848788.2

chr25_+_23591990 0.42 ENSDART00000151938
ENSDART00000089199
cpt1ab
carnitine palmitoyltransferase 1Ab (liver)
chr20_+_263056 0.42 ENSDART00000132669
tube1
tubulin, epsilon 1
chr8_-_3336273 0.42 ENSDART00000081160
zgc:173737
zgc:173737
chr21_+_39197418 0.41 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr7_+_47243564 0.41 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr19_-_35400819 0.39 ENSDART00000148080
rnf19b
ring finger protein 19B
chr14_+_36521005 0.39 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr5_+_40224938 0.38 ENSDART00000142897
si:dkey-193c22.2
si:dkey-193c22.2
chr8_+_20956078 0.38 ENSDART00000136397
si:dkeyp-82a1.2
si:dkeyp-82a1.2
chr20_+_18993452 0.37 ENSDART00000025509
tdh
L-threonine dehydrogenase
chr1_-_56951369 0.37 ENSDART00000152294
si:ch211-1f22.2
si:ch211-1f22.2
chr22_-_7168571 0.37 ENSDART00000165549
asic1b
acid-sensing (proton-gated) ion channel 1b
chr10_+_23548674 0.37 ENSDART00000079686
zmp:0000001103
zmp:0000001103
chr3_-_29977495 0.37 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr6_-_48087152 0.36 ENSDART00000180614
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr3_+_36366053 0.36 ENSDART00000181140
rgs9a
regulator of G protein signaling 9a
chr18_+_33788340 0.36 ENSDART00000136950
si:dkey-145c18.2
si:dkey-145c18.2
chr18_+_33762090 0.36 ENSDART00000147605
si:dkey-145c18.4
si:dkey-145c18.4
chr4_-_30528239 0.35 ENSDART00000169290
znf1052
zinc finger protein 1052
chr10_-_24319526 0.35 ENSDART00000148480
inpp5kb
inositol polyphosphate-5-phosphatase Kb
chr21_+_39197628 0.35 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr16_+_41135018 0.35 ENSDART00000139435
si:ch211-53m15.2
si:ch211-53m15.2
chr12_-_30359031 0.34 ENSDART00000192628
tdrd1
tudor domain containing 1
chr12_-_25217217 0.33 ENSDART00000152931
kcng3
potassium voltage-gated channel, subfamily G, member 3
chr12_-_30358836 0.33 ENSDART00000152878
tdrd1
tudor domain containing 1
chr1_-_40914752 0.33 ENSDART00000113087
hmx1
H6 family homeobox 1
chr11_-_25324534 0.33 ENSDART00000158598
si:ch211-232b12.5
si:ch211-232b12.5
chr24_+_17345521 0.32 ENSDART00000024722
ENSDART00000154250
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr5_-_37252111 0.32 ENSDART00000185110
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr15_-_23699737 0.32 ENSDART00000078311
zgc:154093
zgc:154093
chr4_-_29833326 0.31 ENSDART00000150596
si:ch211-231i17.4
si:ch211-231i17.4
chr4_-_16345227 0.31 ENSDART00000079521
kera
keratocan
chr6_-_9922266 0.31 ENSDART00000151549
pimr73
Pim proto-oncogene, serine/threonine kinase, related 73
chr22_+_34694217 0.30 ENSDART00000111793
hykk.1
hydroxylysine kinase, tandem duplicate 1
chr23_-_10831995 0.30 ENSDART00000142533
pdzrn3a
PDZ domain containing RING finger 3a
chr6_-_29049022 0.30 ENSDART00000190309
evi5b
ecotropic viral integration site 5b
chr4_-_49875682 0.29 ENSDART00000185921
si:dkey-156k2.3
si:dkey-156k2.3
chr21_-_31286428 0.29 ENSDART00000185334
ca4c
carbonic anhydrase IV c
chr14_+_36521553 0.29 ENSDART00000136233
TENM3
si:dkey-237h12.3
chr13_-_31866276 0.28 ENSDART00000140164
syt14a
synaptotagmin XIVa
chr14_+_22297257 0.28 ENSDART00000113676
atp10b
ATPase phospholipid transporting 10B
chr3_+_19336286 0.27 ENSDART00000111528
kri1
KRI1 homolog
chr16_-_22747125 0.27 ENSDART00000179865
tlr19
toll-like receptor 19
chr11_+_2642013 0.27 ENSDART00000111324
zgc:193807
zgc:193807
chr12_-_36070473 0.26 ENSDART00000165720
gpr142
G protein-coupled receptor 142
chr20_+_48100261 0.26 ENSDART00000158604
xkr5a
XK related 5a
chr1_-_57129179 0.26 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
si:ch73-94k4.2
chr8_-_44015210 0.25 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr8_-_15991801 0.24 ENSDART00000132005
agbl4
ATP/GTP binding protein-like 4
chr7_-_3721671 0.24 ENSDART00000062732
si:ch211-282j17.8
si:ch211-282j17.8
chr17_+_15674052 0.24 ENSDART00000156726
bach2a
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr23_+_21966447 0.24 ENSDART00000189378
lactbl1a
lactamase, beta-like 1a
chr21_-_28235361 0.24 ENSDART00000164458
nrxn2a
neurexin 2a
chr24_+_19986432 0.23 ENSDART00000184402
CR381686.5

chr15_-_28805493 0.23 ENSDART00000179617
cd3eap
CD3e molecule, epsilon associated protein
chr13_+_2448251 0.22 ENSDART00000188361
arfgef3
ARFGEF family member 3
chr17_-_50071748 0.22 ENSDART00000075188
zgc:113886
zgc:113886
chr5_+_22459087 0.22 ENSDART00000134781
BX546499.1

chr4_+_9450415 0.22 ENSDART00000189690
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr22_+_35205968 0.21 ENSDART00000150467
tsc22d2
TSC22 domain family 2
chr16_+_5901835 0.21 ENSDART00000060519
ulk4
unc-51 like kinase 4
chr24_+_1294176 0.20 ENSDART00000106637
si:ch73-134f24.1
si:ch73-134f24.1
chr20_+_23960525 0.20 ENSDART00000042123
cx52.6
connexin 52.6
chr15_+_2421729 0.20 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr9_-_53422084 0.20 ENSDART00000162661
gpc6b
glypican 6b
chr1_+_39865748 0.19 ENSDART00000131954
ENSDART00000130270
irf2a
interferon regulatory factor 2a
chr2_-_22575851 0.19 ENSDART00000182932
FQ377628.2

chr20_+_18992679 0.19 ENSDART00000147105
ENSDART00000152811
tdh
L-threonine dehydrogenase
chr10_-_40964739 0.19 ENSDART00000076359
npffr1l1
neuropeptide FF receptor 1 like 1
chr21_+_25216397 0.18 ENSDART00000130970
sycn.3
syncollin, tandem duplicate 3
chr15_-_25198107 0.18 ENSDART00000159793
mnta
MAX network transcriptional repressor a
chr17_+_38602602 0.18 ENSDART00000187996
ccdc88c
coiled-coil domain containing 88C
chr19_+_37701450 0.17 ENSDART00000087694
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr3_-_41795917 0.17 ENSDART00000182662
grifin
galectin-related inter-fiber protein
chr3_+_17939828 0.17 ENSDART00000185047
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr2_+_25278107 0.17 ENSDART00000131977
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr14_-_25309058 0.16 ENSDART00000159569
htr4
5-hydroxytryptamine receptor 4
chr16_+_23600041 0.16 ENSDART00000186918
kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr25_+_17860962 0.15 ENSDART00000163153
pth1a
parathyroid hormone 1a
chr1_-_56223913 0.15 ENSDART00000019573
zgc:65894
zgc:65894
chr6_-_39080630 0.14 ENSDART00000021520
ENSDART00000128308
eif4bb
eukaryotic translation initiation factor 4Bb
chr23_+_1276006 0.14 ENSDART00000162294
utrn
utrophin
chr22_-_4880603 0.14 ENSDART00000134055
si:ch73-256j6.5
si:ch73-256j6.5
chr24_-_18446604 0.12 ENSDART00000144203
sec61g
Sec61 translocon gamma subunit
chr25_+_27923846 0.12 ENSDART00000047007
slc13a1
solute carrier family 13 member 1
chr9_-_6208067 0.12 ENSDART00000032368
tmtops2b
teleost multiple tissue opsin 2b
chr9_-_10778615 0.12 ENSDART00000182577
CABZ01053619.1

chr15_+_20530649 0.11 ENSDART00000186312
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr12_+_48581588 0.11 ENSDART00000114996
CABZ01078415.1

chr19_-_32600138 0.11 ENSDART00000052101
zgc:91944
zgc:91944
chr5_-_68927728 0.11 ENSDART00000132838
ank1a
ankyrin 1, erythrocytic a

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR+nr1i2_vdrb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
1.0 3.0 GO:0090247 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.4 1.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 1.7 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.3 5.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.3 17.0 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.3 0.9 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 1.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.9 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 1.0 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 0.5 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 1.0 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.1 3.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 2.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 8.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.6 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.5 GO:0002931 response to ischemia(GO:0002931)
0.1 3.5 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 2.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.7 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 0.6 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0001840 neural plate development(GO:0001840)
0.0 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.4 GO:0070874 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 2.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.5 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 0.3 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.2 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.5 GO:0032438 melanosome organization(GO:0032438)
0.0 0.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 5.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0070252 actin-mediated cell contraction(GO:0070252)
0.0 1.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.2 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.2 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 3.0 GO:0014704 intercalated disc(GO:0014704)
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.6 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.7 GO:0071546 pi-body(GO:0071546)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 18.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 4.2 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 3.9 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 1.6 GO:2001070 starch binding(GO:2001070)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.3 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 0.7 GO:0070513 death domain binding(GO:0070513)
0.1 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 4.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 6.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.7 GO:0034584 piRNA binding(GO:0034584)
0.1 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.3 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.8 GO:0019840 retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.0 3.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 13.2 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.7 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 17.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 4.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 3.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis