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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for arid3a+arid3b+arid3c

Z-value: 0.72

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Transcription factors associated with arid3a+arid3b+arid3c

Gene Symbol Gene ID Gene Info
arid3c
ENSDARG00000067729 AT rich interactive domain 3C (BRIGHT-like)
arid3a
ENSDARG00000070843 AT rich interactive domain 3A (BRIGHT-like)
arid3b
ENSDARG00000104034 AT rich interactive domain 3B (BRIGHT-like)
arid3c
ENSDARG00000114447 AT rich interactive domain 3C (BRIGHT-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid3adr11_v1_chr11_+_5681762_56817620.406.6e-05Click!
arid3cdr11_v1_chr5_+_41322783_413227830.372.5e-04Click!
arid3bdr11_v1_chr25_-_29072162_290721620.223.3e-02Click!

Activity profile of arid3a+arid3b+arid3c motif

Sorted Z-values of arid3a+arid3b+arid3c motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_3167729 13.29 ENSDART00000110763
ENSDART00000145710
ENSDART00000074620
ENSDART00000105174
stm
starmaker
chr5_+_70155935 4.60 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr2_-_9489611 4.29 ENSDART00000146715
st6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr1_+_31112436 4.26 ENSDART00000075340
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr1_+_7517454 4.13 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr2_-_9059955 3.45 ENSDART00000022768
ak5
adenylate kinase 5
chr15_+_39096736 3.07 ENSDART00000129511
ENSDART00000014877
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr8_+_3820134 2.86 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr12_+_8168272 2.63 ENSDART00000054092
arid5b
AT-rich interaction domain 5B
chr8_+_31717175 2.51 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr15_+_47362728 2.44 ENSDART00000180712
CABZ01099833.1

chr8_+_31716872 2.43 ENSDART00000161121
oxct1a
3-oxoacid CoA transferase 1a
chr19_-_11208782 2.21 ENSDART00000044426
ENSDART00000189754
si:dkey-240h12.4
si:dkey-240h12.4
chr18_-_48296793 2.18 ENSDART00000032184
ENSDART00000193076
CABZ01069595.1

chr18_+_6126506 2.08 ENSDART00000125725
si:ch1073-390k14.1
si:ch1073-390k14.1
chr21_+_13861589 2.05 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr2_+_33457310 2.04 ENSDART00000056657
zgc:113531
zgc:113531
chr21_-_42831033 2.02 ENSDART00000160998
stk10
serine/threonine kinase 10
chr7_+_9189547 2.00 ENSDART00000169783
pcsk6
proprotein convertase subtilisin/kexin type 6
chr8_+_7144066 1.92 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr4_+_14660769 1.84 ENSDART00000168152
ENSDART00000013990
ENSDART00000079987
abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr19_+_24872159 1.84 ENSDART00000158490
si:ch211-195b13.1
si:ch211-195b13.1
chr23_+_21544227 1.76 ENSDART00000140253
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr9_+_2574122 1.75 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr4_+_9669717 1.75 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr10_+_45031398 1.73 ENSDART00000160536
gnsb
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr16_-_42461263 1.72 ENSDART00000109259
smarcc1a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr16_-_55028740 1.69 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr9_-_40765868 1.61 ENSDART00000138634
abca12
ATP-binding cassette, sub-family A (ABC1), member 12
chr16_-_13730152 1.61 ENSDART00000138772
ttyh1
tweety family member 1
chr9_+_34641237 1.59 ENSDART00000133996
shox
short stature homeobox
chr18_+_39416357 1.58 ENSDART00000183174
ENSDART00000127955
ENSDART00000171303
lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr19_-_3240605 1.56 ENSDART00000105168
si:ch211-133n4.4
si:ch211-133n4.4
chr5_-_42180205 1.54 ENSDART00000145247
fam222ba
family with sequence similarity 222, member Ba
chr6_+_54221654 1.51 ENSDART00000128456
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr16_-_8927425 1.51 ENSDART00000000382
triob
trio Rho guanine nucleotide exchange factor b
chr19_-_31372896 1.50 ENSDART00000046609
scin
scinderin
chr8_-_34052019 1.50 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr3_-_5228841 1.46 ENSDART00000092373
ENSDART00000182438
myh9b
myosin, heavy chain 9b, non-muscle
chr19_-_7406933 1.45 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr19_-_34063567 1.45 ENSDART00000157815
ENSDART00000183907
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr11_-_43200994 1.43 ENSDART00000164700
sptbn1
spectrin, beta, non-erythrocytic 1
chr25_+_37126921 1.36 ENSDART00000124331
si:ch1073-174d20.1
si:ch1073-174d20.1
chr10_-_4375190 1.33 ENSDART00000016102
CABZ01073795.1

chr17_-_16965809 1.32 ENSDART00000153697
nrxn3a
neurexin 3a
chr14_-_12051610 1.32 ENSDART00000193741
ENSDART00000029366
zgc:66447
zgc:66447
chr6_+_11989537 1.31 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr17_+_2063693 1.30 ENSDART00000182349
zgc:162989
zgc:162989
chr3_+_60721342 1.30 ENSDART00000157772
foxj1a
forkhead box J1a
chr11_-_889845 1.29 ENSDART00000162152
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr11_-_3343463 1.26 ENSDART00000066177
tuba2
tubulin, alpha 2
chr3_+_17634952 1.26 ENSDART00000191833
rab5c
RAB5C, member RAS oncogene family
chr19_-_38539670 1.22 ENSDART00000136775
col16a1
collagen, type XVI, alpha 1
chr14_-_1635296 1.21 ENSDART00000186658
LO018564.1

chr12_+_3022882 1.20 ENSDART00000122905
rac3b
Rac family small GTPase 3b
chr10_-_2522588 1.16 ENSDART00000081926
CU856539.1

chr11_+_39672874 1.16 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr17_+_22311413 1.14 ENSDART00000151929
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr9_+_38369872 1.13 ENSDART00000193914
plcd4b
phospholipase C, delta 4b
chr22_+_12366516 1.12 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr22_-_26945493 1.12 ENSDART00000077411
cxcl12b
chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)
chr3_-_21280373 1.11 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr6_-_12275836 1.11 ENSDART00000189980
pkp4
plakophilin 4
chr16_+_36126310 1.11 ENSDART00000166040
ENSDART00000189802
sh3bp5b
SH3-domain binding protein 5b (BTK-associated)
chr5_+_5398966 1.11 ENSDART00000139553
mapkap1
mitogen-activated protein kinase associated protein 1
chr8_-_17067364 1.10 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr10_+_22510280 1.09 ENSDART00000109070
ENSDART00000182002
ENSDART00000192852
gigyf1b
GRB10 interacting GYF protein 1b
chr13_+_27951688 1.08 ENSDART00000050303
b3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr2_+_3472832 1.07 ENSDART00000115278
cx47.1
connexin 47.1
chr14_+_28281744 1.07 ENSDART00000173292
mid2
midline 2
chr16_+_32014552 1.05 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr6_-_8360918 1.03 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr24_-_3426620 1.02 ENSDART00000184346
nck1b
NCK adaptor protein 1b
chr7_+_60551133 1.02 ENSDART00000148038
lrfn4b
leucine rich repeat and fibronectin type III domain containing 4b
chr7_+_57866292 1.00 ENSDART00000138757
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr6_-_33871055 0.99 ENSDART00000115409
mast2
microtubule associated serine/threonine kinase 2
chr5_+_4436405 0.99 ENSDART00000167969
CABZ01079241.1

chr9_-_32604414 0.98 ENSDART00000088876
ENSDART00000166502
satb2
SATB homeobox 2
chr13_+_4883377 0.98 ENSDART00000181530
ENSDART00000092521
micu1
mitochondrial calcium uptake 1
chr18_+_11858397 0.95 ENSDART00000133762
tmtc2b
transmembrane and tetratricopeptide repeat containing 2b
chr11_-_26832685 0.95 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr24_-_37484123 0.94 ENSDART00000111623
cluap1
clusterin associated protein 1
chr19_+_4139065 0.93 ENSDART00000172524
si:dkey-218f9.10
si:dkey-218f9.10
chr12_+_7445595 0.92 ENSDART00000103536
ENSDART00000152524
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr17_-_36936649 0.92 ENSDART00000145236
dpysl5a
dihydropyrimidinase-like 5a
chr11_+_691734 0.91 ENSDART00000191463
timp4.1
TIMP metallopeptidase inhibitor 4, tandem duplicate 1
chr22_+_5103349 0.91 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr17_-_1174960 0.91 ENSDART00000161202
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17
chr8_-_29930821 0.89 ENSDART00000125173
ercc6l2
excision repair cross-complementation group 6-like 2
chr6_-_55309190 0.88 ENSDART00000162117
ube2c
ubiquitin-conjugating enzyme E2C
chr15_+_42285643 0.86 ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr3_+_60828813 0.86 ENSDART00000128260
CABZ01087514.1

chr13_+_31550185 0.85 ENSDART00000127843
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr5_+_46277593 0.85 ENSDART00000045598
zgc:110626
zgc:110626
chr4_+_25912308 0.83 ENSDART00000167845
ENSDART00000136927
vezt
vezatin, adherens junctions transmembrane protein
chr22_+_27090136 0.83 ENSDART00000136770
si:dkey-246e1.3
si:dkey-246e1.3
chr2_+_34967022 0.82 ENSDART00000134926
astn1
astrotactin 1
chr14_-_16082806 0.81 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr10_-_14943281 0.81 ENSDART00000143608
smad2
SMAD family member 2
chr19_-_26869103 0.80 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr15_+_36941490 0.80 ENSDART00000172664
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr3_-_21037840 0.79 ENSDART00000002393
rundc3aa
RUN domain containing 3Aa
chr15_-_33807758 0.79 ENSDART00000158445
pds5b
PDS5 cohesin associated factor B
chr11_-_875381 0.78 ENSDART00000173325
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr6_+_47843760 0.78 ENSDART00000140943
padi2
peptidyl arginine deiminase, type II
chr13_+_18371208 0.75 ENSDART00000138172
ccar1
cell division cycle and apoptosis regulator 1
chr11_-_891674 0.75 ENSDART00000172904
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr5_-_12407194 0.75 ENSDART00000125291
ksr2
kinase suppressor of ras 2
chr11_+_24819624 0.75 ENSDART00000155514
kdm5ba
lysine (K)-specific demethylase 5Ba
chr22_+_18389271 0.74 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr14_-_24761132 0.73 ENSDART00000146299
slit3
slit homolog 3 (Drosophila)
chr14_-_7045009 0.72 ENSDART00000112082
rufy1
RUN and FYVE domain containing 1
chr19_-_12145390 0.72 ENSDART00000143087
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr10_+_45089820 0.72 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr22_-_15562933 0.71 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr4_+_13931578 0.71 ENSDART00000142466
pphln1
periphilin 1
chr1_-_1627487 0.71 ENSDART00000166094
clic6
chloride intracellular channel 6
chr4_-_74892355 0.71 ENSDART00000188725
PHF21B
PHD finger protein 21B
chr21_-_3606539 0.69 ENSDART00000062418
dym
dymeclin
chr25_-_6420800 0.69 ENSDART00000153768
ptpn9a
protein tyrosine phosphatase, non-receptor type 9, a
chr10_+_15967643 0.68 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr3_-_25275364 0.67 ENSDART00000163782
ENSDART00000145420
ENSDART00000133718
ENSDART00000055492
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr23_-_20051369 0.67 ENSDART00000049836
bgnb
biglycan b
chr12_-_18961289 0.66 ENSDART00000168405
ep300a
E1A binding protein p300 a
chr10_+_20628698 0.66 ENSDART00000064666
prnpb
prion protein b
chr20_-_22464250 0.66 ENSDART00000165904
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr2_-_22530969 0.65 ENSDART00000159641
znf644a
zinc finger protein 644a
chr20_+_18943406 0.65 ENSDART00000193590
mtmr9
myotubularin related protein 9
chr3_+_26019426 0.65 ENSDART00000135389
ENSDART00000182411
foxred2
FAD-dependent oxidoreductase domain containing 2
chr12_+_1609563 0.65 ENSDART00000163559
SLC39A11
solute carrier family 39 member 11
chr12_+_25223843 0.65 ENSDART00000077180
ENSDART00000127454
ENSDART00000122665
mta3
metastasis associated 1 family, member 3
chr15_+_37197494 0.65 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr15_-_17960228 0.65 ENSDART00000155898
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr22_-_3275888 0.64 ENSDART00000164743
si:zfos-943e10.1
si:zfos-943e10.1
chr15_-_23467750 0.64 ENSDART00000148804
pdzd3a
PDZ domain containing 3a
chr24_+_40860320 0.64 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr12_-_13650344 0.64 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
stat5b
signal transducer and activator of transcription 5b
chr6_-_16394528 0.63 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr10_-_20706109 0.62 ENSDART00000124751
kcnip3b
Kv channel interacting protein 3b, calsenilin
chr10_-_34870667 0.62 ENSDART00000161272
dclk1a
doublecortin-like kinase 1a
chr1_-_22678471 0.61 ENSDART00000128918
fgfbp1b
fibroblast growth factor binding protein 1b
chr12_+_3871452 0.61 ENSDART00000066546
nif3l1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr8_+_25145464 0.61 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr25_+_10762016 0.61 ENSDART00000131231
ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr12_-_34258384 0.60 ENSDART00000109196
pgs1
phosphatidylglycerophosphate synthase 1
chr17_+_24222190 0.60 ENSDART00000181698
ENSDART00000189411
ehbp1
EH domain binding protein 1
chr19_-_46018152 0.59 ENSDART00000159206
krit1
KRIT1, ankyrin repeat containing
chr7_-_28549361 0.59 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
st5
suppression of tumorigenicity 5
chr21_+_45758498 0.58 ENSDART00000162548
h2afy
H2A histone family, member Y
chr13_-_5978433 0.58 ENSDART00000102555
actr2b
ARP2 actin related protein 2b homolog
chr9_+_33158191 0.58 ENSDART00000180786
dopey2
dopey family member 2
chr3_+_58833306 0.57 ENSDART00000113223
igl1c3
immunoglobulin light 1 constant 3
chr7_+_11197940 0.57 ENSDART00000081346
cemip
cell migration inducing protein, hyaluronan binding
chr4_-_25911609 0.57 ENSDART00000186958
ENSDART00000175487
fgd6
FYVE, RhoGEF and PH domain containing 6
chr16_+_14812585 0.57 ENSDART00000134087
col14a1a
collagen, type XIV, alpha 1a
chr2_-_52365251 0.56 ENSDART00000097716
tle2c
transducin like enhancer of split 2c
chr6_-_19035749 0.56 ENSDART00000187714
sept9b
septin 9b
chr23_+_42810055 0.56 ENSDART00000186647
myl9a
myosin, light chain 9a, regulatory
chr21_+_6613772 0.56 ENSDART00000159645
col5a1
procollagen, type V, alpha 1
chr6_+_58698475 0.56 ENSDART00000056138
igsf8
immunoglobulin superfamily, member 8
chr3_+_34919810 0.56 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr18_-_19103929 0.55 ENSDART00000188370
ENSDART00000177621
dennd4a
DENN/MADD domain containing 4A
chr1_+_9886991 0.55 ENSDART00000135702
rgs11
regulator of G protein signaling 11
chr8_+_104114 0.55 ENSDART00000172101
sncaip
synuclein, alpha interacting protein
chr1_+_58182400 0.55 ENSDART00000144784
si:ch211-15j1.1
si:ch211-15j1.1
chr5_-_68058168 0.54 ENSDART00000177026
rnf167
ring finger protein 167
chr25_+_14165447 0.54 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr17_-_7060477 0.54 ENSDART00000081797
sash1b
SAM and SH3 domain containing 1b
chr15_+_33843596 0.52 ENSDART00000169037
inpp5ka
inositol polyphosphate-5-phosphatase Ka
chr1_+_52662203 0.52 ENSDART00000141530
osbp
oxysterol binding protein
chr10_-_44981295 0.52 ENSDART00000166528
purbb
purine-rich element binding protein Bb
chr4_-_75157223 0.52 ENSDART00000174127
CABZ01066312.1

chr5_-_26284276 0.52 ENSDART00000148608
arvcfb
ARVCF, delta catenin family member b
chr3_+_62339264 0.52 ENSDART00000174569
BX470259.3

chr15_-_1733235 0.51 ENSDART00000023153
ENSDART00000154668
rabgef1l
RAB guanine nucleotide exchange factor (GEF) 1, like
chr25_-_518656 0.51 ENSDART00000156421
myo9ab
myosin IXAb
chr20_+_35208020 0.51 ENSDART00000153315
ENSDART00000045135
fbxo16
F-box protein 16
chr8_+_25892319 0.50 ENSDART00000187167
ENSDART00000078163
tmem115
transmembrane protein 115
chr25_-_13549577 0.50 ENSDART00000166772
ano10b
anoctamin 10b
chr11_-_31276064 0.50 ENSDART00000141062
ENSDART00000004780
man2b1
mannosidase, alpha, class 2B, member 1
chr11_+_14199802 0.50 ENSDART00000102520
ENSDART00000133172
palm1a
paralemmin 1a
chr19_+_15521997 0.50 ENSDART00000003164
ppp1r8a
protein phosphatase 1, regulatory subunit 8a
chr25_+_34407529 0.50 ENSDART00000156751
OTUD7A
si:dkey-37f18.2
chr3_+_46271911 0.49 ENSDART00000186557
ENSDART00000113531
mkl2b
MKL/myocardin-like 2b
chr1_+_49682312 0.48 ENSDART00000136747
si:ch211-149l1.2
si:ch211-149l1.2
chr3_-_18711288 0.48 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr1_-_52790724 0.48 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr1_+_2321384 0.47 ENSDART00000157662
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr5_+_66433287 0.47 ENSDART00000170757
kntc1
kinetochore associated 1
chr16_-_51254694 0.46 ENSDART00000148894
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr10_+_42358426 0.46 ENSDART00000025691
dbnla
drebrin-like a
chr25_+_34749187 0.45 ENSDART00000141473
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr16_-_36979592 0.45 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr4_+_15944245 0.45 ENSDART00000134594
si:dkey-117n7.3
si:dkey-117n7.3
chr10_+_5414224 0.44 ENSDART00000138821
nfil3
nuclear factor, interleukin 3 regulated
chr8_+_9715010 0.44 ENSDART00000139414
gripap1
GRIP1 associated protein 1
chr5_-_67349916 0.44 ENSDART00000144092
mlxip
MLX interacting protein
chr20_+_50852356 0.44 ENSDART00000167517
ENSDART00000168396
gphnb
gephyrin b
chr18_-_21910991 0.43 ENSDART00000089787
ENSDART00000169220
ENSDART00000132381
ENSDART00000191764
edc4
enhancer of mRNA decapping 4
chr18_-_47662696 0.43 ENSDART00000184260
CABZ01073963.1

Network of associatons between targets according to the STRING database.

First level regulatory network of arid3a+arid3b+arid3c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 13.3 GO:0045299 otolith mineralization(GO:0045299)
1.0 4.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.9 4.6 GO:2000051 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 2.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.3 4.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 3.1 GO:0050975 sensory perception of touch(GO:0050975)
0.3 1.1 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.3 2.6 GO:0060612 adipose tissue development(GO:0060612)
0.3 1.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 1.3 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 1.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 1.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 1.0 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.2 1.6 GO:0048730 epidermis morphogenesis(GO:0048730)
0.2 1.0 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 0.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.2 0.7 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 1.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 1.0 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.2 0.8 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.4 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.8 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 1.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 2.0 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.3 GO:0015824 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 2.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.4 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 1.0 GO:0045453 bone resorption(GO:0045453)
0.1 0.3 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 1.1 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.9 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 1.5 GO:1900006 auditory receptor cell stereocilium organization(GO:0060088) positive regulation of dendrite development(GO:1900006)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.6 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1 0.6 GO:2001032 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.4 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 3.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.4 GO:2000381 negative regulation of nodal signaling pathway(GO:1900108) negative regulation of mesoderm development(GO:2000381)
0.1 1.4 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.3 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.4 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.3 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 1.1 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.2 GO:0021654 rhombomere boundary formation(GO:0021654)
0.1 3.5 GO:0006414 translational elongation(GO:0006414)
0.1 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.9 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 3.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0032689 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 1.7 GO:0072348 sulfur compound transport(GO:0072348)
0.0 2.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.2 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 3.0 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 0.8 GO:0039022 pronephric duct development(GO:0039022)
0.0 2.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 2.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.5 GO:0060021 palate development(GO:0060021)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 3.0 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 2.0 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)
0.0 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0021703 locus ceruleus development(GO:0021703)
0.0 1.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 1.9 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 1.8 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 2.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.2 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.5 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.7 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.0 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.9 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0008091 spectrin(GO:0008091)
0.3 1.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.0 GO:0002102 podosome(GO:0002102)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 3.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.0 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 2.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.8 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0001726 ruffle(GO:0001726)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.6 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.9 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.8 4.1 GO:0043295 glutathione binding(GO:0043295)
0.6 2.8 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.5 4.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 1.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.6 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.2 1.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.7 GO:0016805 dipeptidase activity(GO:0016805)
0.2 0.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 3.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 4.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 1.9 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.0 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.1 GO:0071949 FAD binding(GO:0071949)
0.0 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 4.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 4.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 1.8 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 4.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 2.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 1.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 3.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction