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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for arid5a+arid6

Z-value: 0.86

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Transcription factors associated with arid5a+arid6

Gene Symbol Gene ID Gene Info
arid6
ENSDARG00000069988 AT-rich interaction domain 6
arid5a
ENSDARG00000077120 AT rich interactive domain 5A (MRF1-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid5adr11_v1_chr8_+_52377516_523775160.151.6e-01Click!
arid6dr11_v1_chr21_+_11244068_112440680.084.7e-01Click!

Activity profile of arid5a+arid6 motif

Sorted Z-values of arid5a+arid6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_3585934 7.29 ENSDART00000055694
cdab
cytidine deaminase b
chr7_-_12968689 7.24 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr15_-_21155641 6.44 ENSDART00000061098
ENSDART00000046443
A2ML1 (1 of many)
si:dkey-105h12.2
chr7_+_39385540 5.95 ENSDART00000139240
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr7_+_10610791 5.60 ENSDART00000166064
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr1_+_10051763 5.41 ENSDART00000011701
fgb
fibrinogen beta chain
chr15_-_452347 5.12 ENSDART00000115233
VSTM5
V-set and transmembrane domain containing 5
chr20_+_46925581 5.12 ENSDART00000192531
si:ch73-21k16.5
si:ch73-21k16.5
chr7_+_39446247 4.97 ENSDART00000033610
ENSDART00000099015
tnnt3b
troponin T type 3b (skeletal, fast)
chr22_-_24880824 4.91 ENSDART00000061165
vtg2
vitellogenin 2
chr13_-_9895564 4.87 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
si:ch211-117n7.6
chr23_+_26017227 4.81 ENSDART00000002939
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_+_36457888 4.73 ENSDART00000155100
si:dkey-262k9.2
si:dkey-262k9.2
chr4_-_8043839 4.70 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
si:ch211-240l19.5
chr15_-_21165237 4.68 ENSDART00000157069
A2ML1 (1 of many)
si:ch211-212c13.8
chr15_-_26552393 4.56 ENSDART00000150152
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr17_+_43867889 4.52 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr1_+_29068654 4.49 ENSDART00000053932
cbsa
cystathionine-beta-synthase a
chr1_-_59313465 4.41 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr16_+_26777473 4.41 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr14_-_1454045 4.31 ENSDART00000161460
pmt
phosphoethanolamine methyltransferase
chr22_+_25753972 4.30 ENSDART00000188417
AL929192.2

chr22_-_24858042 4.30 ENSDART00000137998
ENSDART00000078216
ENSDART00000138378
vtg7
vitellogenin 7
chr21_-_7940043 4.26 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr5_+_32221755 4.18 ENSDART00000125917
myhc4
myosin heavy chain 4
chr7_-_30926030 4.14 ENSDART00000075421
sord
sorbitol dehydrogenase
chr3_-_61205711 4.08 ENSDART00000055062
pvalb1
parvalbumin 1
chr22_+_25693295 4.04 ENSDART00000123888
ENSDART00000150783
si:dkeyp-98a7.4
si:dkeyp-98a7.3
si:dkeyp-98a7.4
si:dkeyp-98a7.3
chr25_+_7494181 4.03 ENSDART00000165005
cat
catalase
chr19_+_9295244 4.00 ENSDART00000132255
ENSDART00000144299
si:ch73-15n24.1
si:ch73-15n24.1
chr7_-_30925798 3.97 ENSDART00000149303
sord
sorbitol dehydrogenase
chr14_+_51056605 3.88 ENSDART00000159639
CABZ01078593.1

chr15_-_26552652 3.78 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr8_+_1766206 3.78 ENSDART00000021820
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr3_-_50139860 3.77 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr24_-_11446156 3.68 ENSDART00000143921
ENSDART00000066778
acad11
acyl-CoA dehydrogenase family, member 11
chr24_-_17039638 3.67 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr13_-_12021566 3.67 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr11_-_34097418 3.60 ENSDART00000028301
ENSDART00000138579
tdo2b
tryptophan 2,3-dioxygenase b
chr22_+_25687525 3.57 ENSDART00000135717
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr22_+_25704430 3.55 ENSDART00000143776
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr19_+_43119014 3.55 ENSDART00000023156
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr22_+_25681911 3.51 ENSDART00000113381
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr22_+_1170294 3.48 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr3_+_31039923 3.40 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr22_-_557965 3.39 ENSDART00000001201
bysl
bystin-like
chr12_+_47663419 3.37 ENSDART00000171932
HHEX
hematopoietically expressed homeobox
chr3_+_12816362 3.36 ENSDART00000163743
ENSDART00000170788
cyp2k6
cytochrome P450, family 2, subfamily K, polypeptide 6
chr19_+_14113886 3.32 ENSDART00000169343
kdf1b
keratinocyte differentiation factor 1b
chr16_+_28754403 3.29 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr5_+_28797771 3.28 ENSDART00000188845
ENSDART00000149066
si:ch211-186e20.7
si:ch211-186e20.7
chr14_+_11458044 3.26 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr4_+_391297 3.24 ENSDART00000030215
rpl18a
ribosomal protein L18a
chr22_+_25715925 3.23 ENSDART00000150650
si:dkeyp-98a7.7
si:dkeyp-98a7.7
chr12_-_17863467 3.16 ENSDART00000042006
baiap2l1a
BAI1-associated protein 2-like 1a
chr22_-_17611742 3.11 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr14_+_11457500 3.11 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr4_+_74928675 3.09 ENSDART00000192755
nup50
nucleoporin 50
chr16_-_9694822 3.04 ENSDART00000168748
COLEC10
si:ch211-93i7.4
chr20_-_5267600 3.00 ENSDART00000099258
cyp46a1.4
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr7_+_20645121 2.99 ENSDART00000052922
sat2a
spermidine/spermine N1-acetyltransferase family member 2a
chr18_-_19456269 2.98 ENSDART00000060363
rpl4
ribosomal protein L4
chr5_-_38820046 2.97 ENSDART00000182886
cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr22_+_19552987 2.95 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr2_-_37960688 2.92 ENSDART00000055565
cbln14
cerebellin 14
chr20_+_54024559 2.91 ENSDART00000130767
si:dkey-241l7.4
si:dkey-241l7.4
chr16_-_45917683 2.79 ENSDART00000184289
afp4
antifreeze protein type IV
chr16_-_48400639 2.75 ENSDART00000159372
eif3ha
eukaryotic translation initiation factor 3, subunit H, a
chr25_-_29074064 2.74 ENSDART00000165603
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr13_+_46941930 2.66 ENSDART00000056962
fbxo5
F-box protein 5
chr6_+_7322587 2.60 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr24_-_9991153 2.47 ENSDART00000137794
ENSDART00000106252
ENSDART00000188309
ENSDART00000188266
ENSDART00000188660
ENSDART00000185713
ENSDART00000179773
zgc:152652
zgc:152652
chr6_+_7466223 2.46 ENSDART00000148908
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr9_-_34191627 2.46 ENSDART00000142664
dcaf6
ddb1 and cul4 associated factor 6
chr5_-_2721686 2.45 ENSDART00000169404
hspa5
heat shock protein 5
chr3_+_39566999 2.44 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr24_-_26328721 2.44 ENSDART00000125468
apodb
apolipoprotein Db
chr25_+_23280220 2.40 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr3_-_5228841 2.39 ENSDART00000092373
ENSDART00000182438
myh9b
myosin, heavy chain 9b, non-muscle
chr22_+_21317597 2.37 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr11_-_44906703 2.32 ENSDART00000180591
zgc:171772
zgc:171772
chr24_-_25166416 2.25 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr2_-_57110477 2.23 ENSDART00000181132
slc25a42
solute carrier family 25, member 42
chr22_+_31039091 2.20 ENSDART00000060005
rpl32
ribosomal protein L32
chr21_-_5077715 2.19 ENSDART00000081954
haus1
HAUS augmin-like complex, subunit 1
chr25_+_31323978 2.16 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr7_+_30626378 2.12 ENSDART00000173533
ENSDART00000052541
ccnb2
cyclin B2
chr23_+_383782 2.11 ENSDART00000055148
zgc:101663
zgc:101663
chr5_-_69621227 2.11 ENSDART00000178543
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr24_+_26328787 2.11 ENSDART00000003884
mynn
myoneurin
chr17_+_18031304 2.02 ENSDART00000127259
setd3
SET domain containing 3
chr24_-_32582378 2.01 ENSDART00000066590
rdh12l
retinol dehydrogenase 12, like
chr2_+_21048661 1.98 ENSDART00000156876
rreb1b
ras responsive element binding protein 1b
chr16_+_29492749 1.97 ENSDART00000179680
ctsk
cathepsin K
chr6_+_3680651 1.96 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr15_-_23647078 1.96 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr9_-_42696408 1.92 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr17_-_4395373 1.90 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr25_-_774350 1.89 ENSDART00000166321
ENSDART00000160386
IRAK4
interleukin 1 receptor associated kinase 4
chr19_-_5769553 1.81 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr21_+_974555 1.80 ENSDART00000130648
scarb2c
scavenger receptor class B, member 2c
chr14_+_164556 1.80 ENSDART00000185606
WDR1
WD repeat domain 1
chr15_+_44201056 1.79 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr21_-_22689805 1.79 ENSDART00000157560
ENSDART00000110792
gig2e
grass carp reovirus (GCRV)-induced gene 2e
chr6_+_29086594 1.79 ENSDART00000127695
rpl5b
ribosomal protein L5b
chr13_-_349952 1.77 ENSDART00000133731
ENSDART00000140326
ENSDART00000189389
ENSDART00000185865
ENSDART00000109634
ENSDART00000147058
ENSDART00000142695
si:ch1073-291c23.2
si:ch1073-291c23.2
chr22_-_2959005 1.77 ENSDART00000040701
ing5a
inhibitor of growth family, member 5a
chr1_+_32054159 1.76 ENSDART00000181442
sts
steroid sulfatase (microsomal), isozyme S
chr12_+_46404307 1.76 ENSDART00000185011
BX005305.4

chr19_+_30884960 1.75 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr12_+_20583552 1.75 ENSDART00000170035
arsg
arylsulfatase G
chr23_-_18609475 1.73 ENSDART00000104524
zgc:158296
zgc:158296
chr7_+_8361083 1.71 ENSDART00000102091
jac7
jacalin 7
chr3_+_57820913 1.71 ENSDART00000168101
CU571328.1

chr10_-_39130839 1.71 ENSDART00000061274
ENSDART00000148648
rps25
ribosomal protein S25
chr3_+_3641429 1.70 ENSDART00000092393
plbd1
phospholipase B domain containing 1
chr12_+_13091842 1.70 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
si:ch211-103b1.2
chr6_-_8466717 1.67 ENSDART00000151577
ENSDART00000151800
ENSDART00000151227
si:dkey-217d24.6
si:dkey-217d24.6
chr12_+_46483618 1.66 ENSDART00000186970
BX005305.5

chr21_+_10577527 1.66 ENSDART00000165070
ENSDART00000127963
ccbe1
collagen and calcium binding EGF domains 1
chr5_-_42059869 1.66 ENSDART00000193984
cenpv
centromere protein V
chr1_-_53714885 1.66 ENSDART00000026409
cct4
chaperonin containing TCP1, subunit 4 (delta)
chr24_-_31306724 1.65 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr6_-_42003780 1.65 ENSDART00000032527
cav3
caveolin 3
chr3_-_36824190 1.64 ENSDART00000172943
abcc6b.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2
chr21_+_20903244 1.64 ENSDART00000186193
c7b
complement component 7b
chr7_+_30178253 1.64 ENSDART00000002075
si:ch211-107o10.3
si:ch211-107o10.3
chr10_-_9190831 1.64 ENSDART00000169301
si:dkeyp-41f9.4
si:dkeyp-41f9.4
chr13_-_30996072 1.61 ENSDART00000181661
wdfy4
WDFY family member 4
chr4_+_17671164 1.61 ENSDART00000040445
gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr22_+_737211 1.60 ENSDART00000017305
znf76
zinc finger protein 76
chr23_-_45407631 1.59 ENSDART00000148484
ENSDART00000150186
zgc:101853
zgc:101853
chr23_+_642395 1.59 ENSDART00000186995
irf10
interferon regulatory factor 10
chr21_-_4849029 1.59 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr13_-_28689717 1.58 ENSDART00000101582
pcgf6
polycomb group ring finger 6
chr11_+_44135351 1.58 ENSDART00000182914
FO704721.1

chr25_+_6049639 1.58 ENSDART00000128816
sv2
synaptic vesicle glycoprotein 2
chr16_-_46660680 1.57 ENSDART00000159209
ENSDART00000191929
tmem176l.4
transmembrane protein 176l.4
chr25_+_3318192 1.57 ENSDART00000146154
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr4_-_1914228 1.56 ENSDART00000087835
ano6
anoctamin 6
chr20_+_14789305 1.55 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr12_-_47648538 1.54 ENSDART00000108477
fh
fumarate hydratase
chr23_+_20431388 1.54 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr6_+_27338512 1.54 ENSDART00000155004
klhl30
kelch-like family member 30
chr15_-_1765098 1.54 ENSDART00000149980
ENSDART00000093074
bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
chr7_-_30177691 1.54 ENSDART00000046689
tmed3
transmembrane p24 trafficking protein 3
chr24_-_25691020 1.52 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr17_-_31579715 1.51 ENSDART00000110167
ENSDART00000191092
rpap1
RNA polymerase II associated protein 1
chr12_-_979789 1.50 ENSDART00000128188
daglb
diacylglycerol lipase, beta
chr7_+_20467549 1.49 ENSDART00000173724
si:dkey-33c9.8
si:dkey-33c9.8
chr17_+_6585333 1.49 ENSDART00000124293
adgrf3a
adhesion G protein-coupled receptor F3a
chr19_-_8798178 1.49 ENSDART00000188232
cers2a
ceramide synthase 2a
chr12_+_46443477 1.48 ENSDART00000191873
BX005305.1

chr1_+_53714734 1.47 ENSDART00000114689
pus10
pseudouridylate synthase 10
chr10_-_17222083 1.46 ENSDART00000134059
depdc5
DEP domain containing 5
chr7_+_30178453 1.46 ENSDART00000174420
si:ch211-107o10.3
si:ch211-107o10.3
chr12_-_10567188 1.46 ENSDART00000144283
myof
myoferlin
chr11_-_3535537 1.45 ENSDART00000165329
ENSDART00000009788
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr21_+_43702016 1.44 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr12_+_45238292 1.44 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr25_+_3099073 1.43 ENSDART00000022506
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr18_-_19484919 1.42 ENSDART00000177690
ENSDART00000184949
lctlb
lactase-like b
chr12_+_46462090 1.40 ENSDART00000130748
BX005305.2

chr10_+_15024772 1.40 ENSDART00000135667
si:dkey-88l16.5
si:dkey-88l16.5
chr9_+_32178050 1.39 ENSDART00000169526
coq10b
coenzyme Q10B
chr12_+_46386983 1.39 ENSDART00000183982
BX005305.3
Danio rerio legumain (LOC100005356), mRNA.
chr8_+_54135642 1.39 ENSDART00000170712
brpf1
bromodomain and PHD finger containing, 1
chr7_+_6879534 1.38 ENSDART00000157731
zgc:175248
zgc:175248
chr7_+_21275152 1.36 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr5_-_72058646 1.35 ENSDART00000112955
PRRC2B
proline rich coiled-coil 2B
chr23_+_19655301 1.34 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr7_-_31759394 1.34 ENSDART00000193040
igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr12_+_20700961 1.34 ENSDART00000016099
si:ch211-119c20.2
si:ch211-119c20.2
chr15_+_31820536 1.33 ENSDART00000045921
frya
furry homolog a (Drosophila)
chr2_-_32262287 1.33 ENSDART00000056621
ENSDART00000039717
fam49ba
family with sequence similarity 49, member Ba
chr23_+_28381260 1.33 ENSDART00000162722
zgc:153867
zgc:153867
chr25_-_2355107 1.33 ENSDART00000056121
mrps35
mitochondrial ribosomal protein S35
chr7_+_39399747 1.31 ENSDART00000147037
tnni2b.1
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr10_+_44699734 1.31 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr4_+_1761029 1.29 ENSDART00000026963
pmpcb
peptidase (mitochondrial processing) beta
chr11_+_21076872 1.28 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr21_-_8003782 1.27 ENSDART00000126792
si:dkey-163m14.7
si:dkey-163m14.7
chr24_-_35561672 1.27 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr19_+_4076259 1.27 ENSDART00000160633
zgc:173581
zgc:173581
chr3_+_24207243 1.27 ENSDART00000023454
ENSDART00000136400
adsl
adenylosuccinate lyase
chr12_+_46425800 1.27 ENSDART00000191965
BX005305.1

chr11_+_37905630 1.26 ENSDART00000170303
si:ch211-112f3.4
si:ch211-112f3.4
chr14_-_4120636 1.25 ENSDART00000059230
irf2
interferon regulatory factor 2
chr4_+_13909398 1.25 ENSDART00000187959
ENSDART00000184926
pphln1
periphilin 1
chr5_-_33886495 1.24 ENSDART00000159058
dab2ipb
DAB2 interacting protein b
chr19_-_10295173 1.24 ENSDART00000136697
cnot3b
CCR4-NOT transcription complex, subunit 3b
chr12_+_48220584 1.23 ENSDART00000164392
lrrc20
leucine rich repeat containing 20
chr2_-_57834983 1.23 ENSDART00000185970
sf3a2
splicing factor 3a, subunit 2
chr11_+_25504215 1.23 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b
chr1_+_11822 1.22 ENSDART00000166393
cep97
centrosomal protein 97
chr17_-_15546862 1.20 ENSDART00000091021
col10a1a
collagen, type X, alpha 1a
chr15_-_15968883 1.20 ENSDART00000166583
ENSDART00000154042
synrg
synergin, gamma
chr1_+_158034 1.19 ENSDART00000160843
cul4a
cullin 4A
chr2_+_19195841 1.19 ENSDART00000163137
ENSDART00000161095
elovl1a
ELOVL fatty acid elongase 1a
chr20_+_18993452 1.18 ENSDART00000025509
tdh
L-threonine dehydrogenase

Network of associatons between targets according to the STRING database.

First level regulatory network of arid5a+arid6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.1 3.4 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
1.0 8.1 GO:0019405 alditol catabolic process(GO:0019405)
1.0 4.9 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.9 5.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.9 4.5 GO:0070814 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.8 4.9 GO:0050764 regulation of phagocytosis(GO:0050764)
0.7 2.7 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.7 3.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.5 4.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.5 1.6 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.5 1.6 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.5 1.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.4 3.6 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.4 2.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.4 1.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 2.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.4 1.5 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.4 1.5 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.4 1.5 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.4 5.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 1.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 3.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.3 2.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 3.4 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.3 1.0 GO:0032602 chemokine production(GO:0032602)
0.3 0.9 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.3 3.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 4.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 0.9 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.3 1.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 3.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 0.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.3 4.7 GO:0046688 response to copper ion(GO:0046688)
0.3 1.0 GO:0021564 vagus nerve development(GO:0021564)
0.3 3.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 2.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 1.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 1.7 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.2 1.8 GO:0045109 intermediate filament organization(GO:0045109)
0.2 0.9 GO:0006297 leading strand elongation(GO:0006272) nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 0.9 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.2 1.3 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 17.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 5.0 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.2 1.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 1.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 1.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 0.9 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 11.7 GO:0006414 translational elongation(GO:0006414)
0.2 1.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 2.4 GO:0042026 protein refolding(GO:0042026)
0.2 0.8 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 0.5 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.2 1.5 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.6 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 2.0 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 1.6 GO:0045453 bone resorption(GO:0045453)
0.1 1.2 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 1.3 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 2.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 1.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.9 GO:0006012 galactose metabolic process(GO:0006012)
0.1 3.7 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 2.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 4.7 GO:0032355 response to estradiol(GO:0032355)
0.1 1.0 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.6 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 0.8 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 0.9 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 1.0 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 2.4 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.9 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.5 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 1.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 4.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 2.8 GO:0060030 dorsal convergence(GO:0060030)
0.1 1.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 2.3 GO:0048844 artery morphogenesis(GO:0048844)
0.1 2.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.3 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.7 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 3.5 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.1 1.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.7 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.4 GO:2000319 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T cell differentiation(GO:0045581) regulation of T-helper cell differentiation(GO:0045622) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of alpha-beta T cell differentiation(GO:0046639) regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 2.4 GO:0007568 aging(GO:0007568)
0.1 0.6 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0042181 ketone biosynthetic process(GO:0042181)
0.1 1.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 2.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.8 GO:0060021 palate development(GO:0060021)
0.1 1.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 4.0 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 0.7 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0043476 pigment accumulation(GO:0043476)
0.1 0.6 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.3 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.6 GO:0019835 cytolysis(GO:0019835)
0.1 0.7 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.4 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.2 GO:0090184 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 1.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.8 GO:0045682 regulation of epidermis development(GO:0045682)
0.1 0.8 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.8 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 2.2 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.5 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 5.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.0 1.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.3 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.1 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 2.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.7 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 2.1 GO:0042493 response to drug(GO:0042493)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 4.2 GO:0007051 spindle organization(GO:0007051)
0.0 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0002931 response to ischemia(GO:0002931)
0.0 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 1.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 3.2 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.5 GO:0060348 bone development(GO:0060348)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 2.2 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 9.7 GO:0006412 translation(GO:0006412)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.2 GO:0043113 receptor clustering(GO:0043113)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 5.3 GO:0006914 autophagy(GO:0006914)
0.0 3.6 GO:0006364 rRNA processing(GO:0006364)
0.0 6.1 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.7 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.4 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 2.3 GO:0016485 protein processing(GO:0016485)
0.0 0.9 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.1 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.6 GO:0030282 bone mineralization(GO:0030282)
0.0 0.9 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.1 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.6 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.6 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.9 GO:0010324 membrane invagination(GO:0010324)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.0 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.5 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.8 GO:0048793 pronephros development(GO:0048793)
0.0 0.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.8 GO:0031032 actomyosin structure organization(GO:0031032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0005577 fibrinogen complex(GO:0005577)
1.2 4.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.8 2.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 1.9 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3 3.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 2.7 GO:0042788 polysomal ribosome(GO:0042788)
0.3 2.2 GO:0001772 immunological synapse(GO:0001772)
0.3 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.3 1.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 2.2 GO:0070652 HAUS complex(GO:0070652)
0.2 3.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.5 GO:1990130 Iml1 complex(GO:1990130)
0.2 0.8 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 4.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 0.8 GO:0042641 actomyosin(GO:0042641)
0.2 4.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 10.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 6.9 GO:0005861 troponin complex(GO:0005861)
0.2 1.1 GO:0030914 STAGA complex(GO:0030914)
0.2 2.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.4 GO:1990077 primosome complex(GO:1990077)
0.1 1.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.1 GO:0035101 FACT complex(GO:0035101)
0.1 1.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.1 GO:0030904 retromer complex(GO:0030904)
0.1 2.3 GO:0045178 basal part of cell(GO:0045178) basal cortex(GO:0045180)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.6 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.5 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 1.3 GO:0042555 MCM complex(GO:0042555)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 13.6 GO:0005840 ribosome(GO:0005840)
0.1 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.2 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 3.5 GO:0005643 nuclear pore(GO:0005643)
0.1 1.2 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.2 GO:0030057 desmosome(GO:0030057)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 4.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 5.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 2.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.6 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 24.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.9 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.2 GO:0045735 nutrient reservoir activity(GO:0045735)
1.2 3.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.1 5.6 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.0 7.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.9 4.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.9 2.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.7 2.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.7 2.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.6 3.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.5 4.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.5 3.0 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.5 2.5 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.4 4.0 GO:0004096 catalase activity(GO:0004096)
0.4 2.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.4 1.6 GO:0071253 connexin binding(GO:0071253)
0.4 4.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 1.1 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.4 1.8 GO:0008097 5S rRNA binding(GO:0008097)
0.3 2.4 GO:0019809 spermidine binding(GO:0019809)
0.3 4.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 1.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 1.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.0 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.2 1.2 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.2 1.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.2 1.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 2.5 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.9 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 0.9 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.2 0.8 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.2 3.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.7 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.2 3.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 6.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 3.4 GO:0030515 snoRNA binding(GO:0030515)
0.2 1.0 GO:0017040 ceramidase activity(GO:0017040)
0.2 2.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.4 GO:0048039 ubiquinone binding(GO:0048039)
0.2 2.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 2.0 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 2.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 17.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.6 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 2.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.8 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 21.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.0 GO:0070122 isopeptidase activity(GO:0070122)
0.1 1.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 2.9 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 0.6 GO:1900750 oligopeptide binding(GO:1900750)
0.1 1.7 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 1.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 4.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.7 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.3 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 1.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.9 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
0.1 0.6 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 2.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.4 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 1.2 GO:2001069 glycogen binding(GO:2001069)
0.1 0.6 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.8 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.0 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 7.8 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.1 1.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 15.9 GO:0030246 carbohydrate binding(GO:0030246)
0.1 1.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 1.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.9 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.1 3.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 2.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 1.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 3.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 3.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978)
0.0 0.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.6 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 1.0 GO:0042562 hormone binding(GO:0042562)
0.0 3.0 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.7 PID FOXO PATHWAY FoxO family signaling
0.1 2.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.9 PID AURORA A PATHWAY Aurora A signaling
0.1 2.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.5 PID MYC PATHWAY C-MYC pathway
0.1 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 8.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 5.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 1.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.3 3.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 1.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 2.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 4.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 5.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 3.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 10.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.9 REACTOME SYNTHESIS OF DNA Genes involved in Synthesis of DNA
0.0 1.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 4.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+