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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for atf3+jdp2b

Z-value: 1.93

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Transcription factors associated with atf3+jdp2b

Gene Symbol Gene ID Gene Info
atf3
ENSDARG00000007823 activating transcription factor 3
jdp2b
ENSDARG00000020133 Jun dimerization protein 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf3dr11_v1_chr20_+_37794633_377946330.312.3e-03Click!
jdp2bdr11_v1_chr20_+_46586678_465866920.261.2e-02Click!

Activity profile of atf3+jdp2b motif

Sorted Z-values of atf3+jdp2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_112579 23.89 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr10_+_20256454 23.86 ENSDART00000111097
TCIM (1 of many)
transcriptional and immune response regulator
chr23_-_44723102 21.82 ENSDART00000129138
mogat3a
monoacylglycerol O-acyltransferase 3a
chr5_+_29831235 20.91 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr18_-_5598958 19.83 ENSDART00000161538
cyp1a
cytochrome P450, family 1, subfamily A
chr5_+_57658898 18.58 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr24_-_26328721 18.52 ENSDART00000125468
apodb
apolipoprotein Db
chr14_+_21106444 16.97 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr5_-_29531948 16.48 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr17_-_2039511 15.73 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr1_-_59240975 15.35 ENSDART00000166170
mvb12a
multivesicular body subunit 12A
chr14_-_11456724 15.31 ENSDART00000110424
si:ch211-153b23.4
si:ch211-153b23.4
chr15_+_36054864 15.24 ENSDART00000156697
col4a3
collagen, type IV, alpha 3
chr3_+_39540014 14.92 ENSDART00000074848
zgc:165423
zgc:165423
chr17_+_30894431 14.41 ENSDART00000127996
degs2
delta(4)-desaturase, sphingolipid 2
chr5_+_26213874 13.76 ENSDART00000193816
ENSDART00000098514
oclnb
occludin b
chr3_-_49110710 13.66 ENSDART00000160404
trim35-12
tripartite motif containing 35-12
chr3_+_34670076 12.85 ENSDART00000133457
dlx4a
distal-less homeobox 4a
chr7_-_12968689 12.59 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr10_-_41352502 12.55 ENSDART00000052971
ENSDART00000128156
rab11fip1b
RAB11 family interacting protein 1 (class I) b
chr5_-_26181863 12.50 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr9_-_34269066 12.49 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr15_+_20239141 12.46 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr7_-_20241346 12.33 ENSDART00000173619
ENSDART00000127699
si:ch73-335l21.4
si:ch73-335l21.4
chr1_-_25679339 12.33 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr23_+_19790962 12.14 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr3_-_15734358 11.94 ENSDART00000137325
mvp
major vault protein
chr24_-_12938922 11.90 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr3_+_16922226 11.87 ENSDART00000017646
atp6v0a1a
ATPase H+ transporting V0 subunit a1a
chr2_-_22688651 11.77 ENSDART00000013863
agxtb
alanine-glyoxylate aminotransferase b
chr7_+_6652967 11.71 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr1_-_45157243 11.70 ENSDART00000131882
mucms1
mucin, multiple PTS and SEA group, member 1
chr16_-_45178430 11.68 ENSDART00000165186
si:dkey-33i11.9
si:dkey-33i11.9
chr5_-_69944084 11.67 ENSDART00000188557
ENSDART00000127782
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr22_+_1170294 11.61 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr18_+_2228737 11.43 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr24_-_40668208 11.42 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr20_-_35578435 11.35 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr14_+_11430796 11.22 ENSDART00000165275
si:ch211-153b23.3
si:ch211-153b23.3
chr10_+_252425 11.21 ENSDART00000059478
lrrc32
leucine rich repeat containing 32
chr19_-_977849 11.20 ENSDART00000172303
CABZ01088282.1

chr22_-_10121880 10.93 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr25_+_37435720 10.79 ENSDART00000164390
chmp1a
charged multivesicular body protein 1A
chr24_-_33291784 10.71 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr10_-_322769 10.56 ENSDART00000165244
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr25_+_31227747 10.55 ENSDART00000033872
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr3_-_19561058 10.54 ENSDART00000079323
zgc:163079
zgc:163079
chr8_-_50259448 10.52 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr5_+_45677781 10.45 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr3_+_42923275 10.33 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr7_+_33172066 10.11 ENSDART00000174013
si:ch211-194p6.12
si:ch211-194p6.12
chr17_+_28102487 10.10 ENSDART00000131638
ENSDART00000076265
zgc:91908
zgc:91908
chr15_+_36457888 10.08 ENSDART00000155100
si:dkey-262k9.2
si:dkey-262k9.2
chr22_+_997838 9.95 ENSDART00000149743
pparda
peroxisome proliferator-activated receptor delta a
chr3_+_26814030 9.86 ENSDART00000180128
socs1a
suppressor of cytokine signaling 1a
chr19_-_3781405 9.70 ENSDART00000170609
btr19
bloodthirsty-related gene family, member 19
chr1_+_1896737 9.66 ENSDART00000152442
si:ch211-132g1.6
si:ch211-132g1.6
chr24_-_40667800 9.59 ENSDART00000169315
smyhc1
slow myosin heavy chain 1
chr1_-_59104145 9.55 ENSDART00000132495
ENSDART00000152457
MFAP4 (1 of many)
si:zfos-2330d3.7
si:zfos-2330d3.1
si:zfos-2330d3.7
chr18_+_35842933 9.49 ENSDART00000151587
ENSDART00000131121
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr16_+_33143503 9.45 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr19_+_14113886 9.24 ENSDART00000169343
kdf1b
keratinocyte differentiation factor 1b
chr24_+_35564668 9.23 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr16_+_42772678 9.23 ENSDART00000155575
si:ch211-135n15.2
si:ch211-135n15.2
chr3_-_16784280 9.12 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
si:dkey-30j10.5
chr22_-_10541372 9.07 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr4_-_13502549 9.03 ENSDART00000140366
si:ch211-266a5.12
si:ch211-266a5.12
chr22_-_23666504 9.01 ENSDART00000158665
cfh
complement factor H
chr15_-_36055401 9.01 ENSDART00000154476
col4a4
collagen, type IV, alpha 4
chr21_-_16219400 8.94 ENSDART00000124871
tnfrsfa
tumor necrosis factor receptor superfamily, member a
chr8_+_23725957 8.93 ENSDART00000104346
mkrn4
makorin, ring finger protein, 4
chr6_+_60055168 8.79 ENSDART00000008752
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr16_+_46725087 8.70 ENSDART00000008920
rab11al
RAB11a, member RAS oncogene family, like
chr22_-_22340688 8.67 ENSDART00000105597
si:ch211-129c21.1
si:ch211-129c21.1
chr3_-_61116258 8.64 ENSDART00000009194
ENSDART00000156978
aimp2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr10_-_15053507 8.58 ENSDART00000157446
ENSDART00000170441
CLDN23
si:ch211-95j8.5
chr7_-_52417777 8.49 ENSDART00000110265
myzap
myocardial zonula adherens protein
chr7_+_38750871 8.43 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr6_+_42475730 8.40 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr11_-_8167799 8.23 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
uox
urate oxidase
chr5_-_69934558 8.21 ENSDART00000124954
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr18_-_50799510 8.17 ENSDART00000174373
taldo1
transaldolase 1
chr24_+_21621654 8.15 ENSDART00000002595
rpl21
ribosomal protein L21
chr10_+_76864 8.11 ENSDART00000036375
vps26c
Down syndrome critical region 3
chr4_-_74998614 8.09 ENSDART00000162529
zgc:172139
zgc:172139
chr2_+_24762567 7.99 ENSDART00000078866
ifi30
interferon, gamma-inducible protein 30
chr10_+_40792078 7.98 ENSDART00000140007
si:ch211-139n6.3
si:ch211-139n6.3
chr13_+_646700 7.98 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr1_-_22678471 7.96 ENSDART00000128918
fgfbp1b
fibroblast growth factor binding protein 1b
chr2_-_55779927 7.96 ENSDART00000168579
CABZ01066725.1

chr21_-_45382112 7.93 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr7_+_35268880 7.92 ENSDART00000182231
dpep2
dipeptidase 2
chr2_-_32237916 7.91 ENSDART00000141418
fam49ba
family with sequence similarity 49, member Ba
chr1_-_23274038 7.87 ENSDART00000181658
rfc1
replication factor C (activator 1) 1
chr23_+_28381260 7.87 ENSDART00000162722
zgc:153867
zgc:153867
chr2_+_9560740 7.80 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr21_+_45816030 7.66 ENSDART00000187056
pitx1
paired-like homeodomain 1
chr22_+_26443235 7.65 ENSDART00000044085
zgc:92480
zgc:92480
chr12_+_22588923 7.56 ENSDART00000184862
capgb
capping protein (actin filament), gelsolin-like b
chr19_-_25005609 7.51 ENSDART00000151129
xkr8.2
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 2
chr10_+_38643304 7.48 ENSDART00000067447
mmp30
matrix metallopeptidase 30
chr24_+_39688072 7.43 ENSDART00000167900
zgc:153659
zgc:153659
chr22_-_10156581 7.40 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr22_-_17781213 7.39 ENSDART00000137984
si:ch73-63e15.2
si:ch73-63e15.2
chr24_-_39186185 7.39 ENSDART00000123019
ENSDART00000191114
nubp2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr2_-_6482240 7.36 ENSDART00000132623
rgs13
regulator of G protein signaling 13
chr12_-_49032899 7.36 ENSDART00000159356
GHITM
growth hormone inducible transmembrane protein
chr1_+_5402476 7.25 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr13_-_17464362 7.21 ENSDART00000145499
lrmda
leucine rich melanocyte differentiation associated
chr24_+_37461457 7.15 ENSDART00000165775
nlrc3
NLR family, CARD domain containing 3
chr24_+_10413484 7.08 ENSDART00000111014
myca
MYC proto-oncogene, bHLH transcription factor a
chr9_-_56231387 7.00 ENSDART00000149851
rpl31
ribosomal protein L31
chr7_+_67451108 6.88 ENSDART00000163840
gcshb
glycine cleavage system protein H (aminomethyl carrier), b
chr23_+_34990693 6.87 ENSDART00000013449
CHST13
si:ch211-236h17.3
chr22_-_15593824 6.86 ENSDART00000123125
tpm4a
tropomyosin 4a
chr14_+_39156 6.84 ENSDART00000082184
tmem107
transmembrane protein 107
chr10_+_2600830 6.80 ENSDART00000101012
CU856539.2

chr13_-_319996 6.80 ENSDART00000148675
ddx21
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr6_-_52675630 6.76 ENSDART00000083830
sdc4
syndecan 4
chr23_+_2421689 6.71 ENSDART00000180200
tcp1
t-complex 1
chr4_-_77218637 6.71 ENSDART00000174325
psmb10
proteasome subunit beta 10
chr3_-_33427803 6.68 ENSDART00000075495
rpl23
ribosomal protein L23
chr8_-_36475328 6.68 ENSDART00000048448
si:busm1-266f07.2
si:busm1-266f07.2
chr17_-_43666166 6.67 ENSDART00000077990
egr2a
early growth response 2a
chr3_-_7656059 6.65 ENSDART00000170917
junbb
JunB proto-oncogene, AP-1 transcription factor subunit b
chr3_-_1387292 6.57 ENSDART00000163535
ddx47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr18_+_6558338 6.53 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr25_+_6122823 6.53 ENSDART00000191824
ENSDART00000067514
rbpms2a
RNA binding protein with multiple splicing 2a
chr1_+_1689775 6.50 ENSDART00000048828
atp1a1a.4
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4
chr18_-_16953978 6.50 ENSDART00000100126
akip1
A kinase (PRKA) interacting protein 1
chr10_-_1276046 6.48 ENSDART00000169779
pdlim5b
PDZ and LIM domain 5b
chr19_+_2590182 6.46 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr1_-_44484 6.39 ENSDART00000171547
ENSDART00000164075
ENSDART00000168091
tmem39a
transmembrane protein 39A
chr8_-_25329967 6.39 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr1_-_23274393 6.33 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
rpl9
ribosomal protein L9
chr2_+_40181633 6.32 ENSDART00000185494
FP236331.1

chr12_-_9132682 6.31 ENSDART00000066471
adam8b
ADAM metallopeptidase domain 8b
chr25_-_23526058 6.31 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr3_-_19367081 6.31 ENSDART00000191369
s1pr5a
sphingosine-1-phosphate receptor 5a
chr2_-_37280617 6.26 ENSDART00000190458
nadkb
NAD kinase b
chr13_+_233482 6.26 ENSDART00000102511
cfap36
cilia and flagella associated protein 36
chr8_-_38317914 6.22 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr25_-_35182347 6.21 ENSDART00000115210
ano9a
anoctamin 9a
chr20_-_54245256 6.19 ENSDART00000170482
prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr14_-_12822 6.19 ENSDART00000180650
ENSDART00000188819
msx1a
muscle segment homeobox 1a
chr15_-_37104165 6.18 ENSDART00000165867
zmp:0000001114
zmp:0000001114
chr7_+_10592152 6.18 ENSDART00000182624
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr13_-_41908583 6.18 ENSDART00000136515
ipmka
inositol polyphosphate multikinase a
chr15_-_41689684 6.15 ENSDART00000143447
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr2_+_52232630 6.15 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr5_+_27898226 6.15 ENSDART00000098604
ENSDART00000180251
adam28
ADAM metallopeptidase domain 28
chr20_+_36812368 6.09 ENSDART00000062931
abracl
ABRA C-terminal like
chr16_+_21790870 6.07 ENSDART00000155039
trim108
tripartite motif containing 108
chr4_-_73190246 6.04 ENSDART00000170842
LO018260.1

chr23_-_10722664 6.03 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
foxp1a
forkhead box P1a
chr7_-_19168375 6.02 ENSDART00000112447
il13ra1
interleukin 13 receptor, alpha 1
chr17_-_32370047 6.01 ENSDART00000145487
klf11b
Kruppel-like factor 11b
chr24_+_37406535 5.95 ENSDART00000138264
si:ch211-183d21.1
si:ch211-183d21.1
chr25_+_753364 5.94 ENSDART00000183804
TWF1 (1 of many)
twinfilin actin binding protein 1
chr19_-_25081711 5.92 ENSDART00000058513
xkr8.3
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3
chr18_+_48423973 5.92 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr10_+_4924388 5.91 ENSDART00000108595
slc46a2
solute carrier family 46 member 2
chr25_+_3099073 5.89 ENSDART00000022506
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr15_-_8309207 5.86 ENSDART00000143880
ENSDART00000061351
tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr15_-_41689981 5.83 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr5_-_3991655 5.83 ENSDART00000159368
myo19
myosin XIX
chr16_+_20947439 5.83 ENSDART00000137344
skap2
src kinase associated phosphoprotein 2
chr7_+_41296795 5.82 ENSDART00000173562
si:dkey-86l18.10
si:dkey-86l18.10
chr10_-_14488472 5.81 ENSDART00000101298
ENSDART00000138161
galt
galactose-1-phosphate uridylyltransferase
chr6_+_13201358 5.81 ENSDART00000190290
CT009620.1

chr17_+_15388479 5.81 ENSDART00000052439
si:ch211-266g18.6
si:ch211-266g18.6
chr19_-_2231146 5.79 ENSDART00000181909
ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr24_-_27436319 5.76 ENSDART00000171489
si:dkey-25o1.7
si:dkey-25o1.7
chr24_+_7828613 5.75 ENSDART00000135161
zgc:101569
zgc:101569
chr7_-_24364536 5.74 ENSDART00000064789
txn
thioredoxin
chr13_-_11971148 5.74 ENSDART00000066230
ENSDART00000185614
ARL3 (1 of many)
zgc:110197
chr19_-_12404590 5.71 ENSDART00000103703
ftr56
finTRIM family, member 56
chr2_-_37280028 5.62 ENSDART00000139459
nadkb
NAD kinase b
chr1_+_11659861 5.60 ENSDART00000054787
BX569798.1

chr8_+_52415603 5.59 ENSDART00000021604
ENSDART00000191424
gins4
GINS complex subunit 4 (Sld5 homolog)
chr11_+_16216909 5.58 ENSDART00000081035
ENSDART00000147190
slc25a26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr25_-_6049339 5.57 ENSDART00000075184
snx1a
sorting nexin 1a
chr19_+_10603405 5.55 ENSDART00000151135
si:dkey-211g8.8
si:dkey-211g8.8
chr2_+_36121373 5.55 ENSDART00000187002
CT867973.2

chr4_+_8532580 5.53 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr5_-_28016805 5.52 ENSDART00000078642
vps37b
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr2_-_30721502 5.51 ENSDART00000132389
si:dkey-94e7.1
si:dkey-94e7.1
chr23_-_33738945 5.49 ENSDART00000136386
si:ch211-210c8.7
si:ch211-210c8.7
chr20_+_46925581 5.49 ENSDART00000192531
si:ch73-21k16.5
si:ch73-21k16.5
chr5_+_64856666 5.49 ENSDART00000050863
zgc:101858
zgc:101858
chr4_+_77948970 5.48 ENSDART00000149636
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr8_-_65189 5.48 ENSDART00000168412
hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
chr22_-_607812 5.46 ENSDART00000145983
cdkn1a
cyclin-dependent kinase inhibitor 1A
chr5_+_72145468 5.45 ENSDART00000148626
abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr8_-_43775805 5.44 ENSDART00000090534
ENSDART00000144239
ulk1a
unc-51 like autophagy activating kinase 1a
chr23_+_44049509 5.43 ENSDART00000102003
txk
TXK tyrosine kinase
chr12_+_45238292 5.41 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr13_-_36582341 5.41 ENSDART00000137335
lgals3a
lectin, galactoside binding soluble 3a
chr19_+_43341424 5.40 ENSDART00000134815
sesn2
sestrin 2
chr21_+_20383837 5.40 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11

Network of associatons between targets according to the STRING database.

First level regulatory network of atf3+jdp2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 20.7 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
5.1 15.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
3.0 21.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
3.0 30.0 GO:0006450 regulation of translational fidelity(GO:0006450)
2.7 8.2 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
2.7 16.0 GO:0006545 glycine biosynthetic process(GO:0006545)
2.5 12.7 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
2.4 2.4 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
2.2 8.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.2 2.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
2.1 6.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
2.0 2.0 GO:1903430 negative regulation of cell maturation(GO:1903430)
1.8 10.9 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
1.7 8.7 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
1.7 6.9 GO:0006544 glycine metabolic process(GO:0006544) glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7 11.9 GO:0006741 NADP biosynthetic process(GO:0006741)
1.7 6.8 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
1.6 24.7 GO:0090559 regulation of membrane permeability(GO:0090559)
1.6 9.9 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.6 8.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
1.6 4.9 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
1.5 4.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
1.5 4.5 GO:0007571 age-dependent general metabolic decline(GO:0007571)
1.5 6.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
1.5 7.5 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
1.5 7.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
1.4 10.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
1.4 7.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
1.4 2.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.3 4.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
1.3 5.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
1.3 6.5 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
1.3 3.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.3 17.9 GO:0034311 diol metabolic process(GO:0034311)
1.2 3.7 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.2 32.0 GO:0030168 platelet activation(GO:0030168)
1.2 3.7 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
1.2 5.9 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
1.2 4.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
1.2 4.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.2 5.8 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
1.1 6.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
1.1 5.5 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
1.1 9.9 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
1.1 7.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
1.1 3.2 GO:0070126 mitochondrial translational termination(GO:0070126)
1.0 6.3 GO:0006013 mannose metabolic process(GO:0006013)
1.0 6.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.0 6.2 GO:0006572 tyrosine catabolic process(GO:0006572)
1.0 3.1 GO:0035973 aggrephagy(GO:0035973)
1.0 4.0 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
1.0 12.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
1.0 3.9 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
1.0 2.9 GO:0097435 fibril organization(GO:0097435)
1.0 2.9 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.9 4.7 GO:0051103 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.9 5.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.9 4.6 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.9 13.8 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.9 11.9 GO:0001845 phagolysosome assembly(GO:0001845)
0.9 2.7 GO:0061355 Wnt protein secretion(GO:0061355)
0.9 5.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.9 7.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.9 2.6 GO:0033212 iron assimilation(GO:0033212)
0.9 3.4 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.8 3.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.8 2.5 GO:0090382 phagosome maturation(GO:0090382)
0.8 3.4 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.8 10.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.8 30.5 GO:0030199 collagen fibril organization(GO:0030199)
0.8 3.1 GO:0032790 ribosome disassembly(GO:0032790)
0.8 5.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.8 5.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.8 3.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.8 11.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.7 2.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.7 8.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.7 2.2 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.7 3.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.7 5.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.7 3.6 GO:0048730 epidermis morphogenesis(GO:0048730)
0.7 2.1 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.7 4.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.7 3.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.7 2.1 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.7 4.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.7 9.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 7.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.7 21.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.7 4.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.7 2.0 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.7 2.6 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.7 11.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.7 2.0 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.7 6.5 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.6 1.9 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.6 1.9 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.6 6.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.6 6.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.6 2.5 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.6 2.5 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.6 6.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.6 3.1 GO:0051031 tRNA transport(GO:0051031)
0.6 6.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.6 1.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.6 9.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 10.7 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.6 1.7 GO:0016584 nucleosome positioning(GO:0016584)
0.6 16.1 GO:0007568 aging(GO:0007568)
0.6 4.6 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.6 4.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.6 3.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.6 1.7 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.5 5.5 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.5 1.6 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.5 1.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 3.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.5 4.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.5 2.6 GO:0010447 response to acidic pH(GO:0010447)
0.5 2.0 GO:0014909 smooth muscle cell migration(GO:0014909)
0.5 2.5 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.5 10.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.5 4.0 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.5 2.0 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.5 2.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.5 3.9 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.5 11.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 2.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 5.4 GO:0050909 sensory perception of taste(GO:0050909)
0.5 1.5 GO:0006089 lactate metabolic process(GO:0006089)
0.5 3.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 3.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.4 4.0 GO:0042987 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.4 14.0 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.4 23.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.4 7.4 GO:0051340 regulation of ligase activity(GO:0051340)
0.4 2.1 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 1.3 GO:0042766 nucleosome mobilization(GO:0042766)
0.4 3.4 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.4 1.2 GO:0072540 response to protozoan(GO:0001562) T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) defense response to protozoan(GO:0042832) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.4 2.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.4 1.6 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.4 9.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.4 10.0 GO:0043049 otic placode formation(GO:0043049)
0.4 3.0 GO:0021588 cerebellum formation(GO:0021588)
0.4 7.2 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.4 2.6 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.4 5.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.4 1.9 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.4 3.7 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.4 1.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 0.4 GO:0044819 mitotic G1/S transition checkpoint(GO:0044819)
0.4 1.8 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.4 0.7 GO:0016246 RNA interference(GO:0016246)
0.3 3.8 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.3 3.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.3 2.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 6.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.3 6.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.3 5.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 2.0 GO:0014004 microglia differentiation(GO:0014004)
0.3 1.9 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.3 1.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.3 1.3 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 0.9 GO:0036315 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 2.8 GO:0048532 anatomical structure arrangement(GO:0048532)
0.3 1.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.3 7.2 GO:0051639 actin filament network formation(GO:0051639)
0.3 6.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 6.2 GO:0003181 atrioventricular valve morphogenesis(GO:0003181)
0.3 7.7 GO:0051180 vitamin transport(GO:0051180)
0.3 5.4 GO:0031033 myosin filament organization(GO:0031033)
0.3 3.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 0.9 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.3 7.2 GO:0030261 chromosome condensation(GO:0030261)
0.3 1.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.3 2.6 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.3 3.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.3 1.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 6.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.3 2.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 7.9 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.3 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 2.7 GO:0010889 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.3 2.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 2.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 1.6 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.3 6.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 1.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 1.0 GO:0030091 protein repair(GO:0030091)
0.3 4.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 2.5 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 2.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 2.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 7.6 GO:0051014 actin filament severing(GO:0051014)
0.2 7.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 3.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 5.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.2 1.4 GO:0035989 tendon development(GO:0035989)
0.2 5.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 7.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 4.0 GO:0032392 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.2 11.9 GO:0031102 neuron projection regeneration(GO:0031102)
0.2 0.2 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.2 2.0 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 1.5 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.2 2.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.2 0.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 6.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.2 2.7 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.2 3.1 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine-containing compound transmembrane transport(GO:0072531) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.0 GO:0060339 regulation of type I interferon-mediated signaling pathway(GO:0060338) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 0.6 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.2 2.0 GO:0007584 response to nutrient(GO:0007584)
0.2 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.8 GO:0071632 optomotor response(GO:0071632)
0.2 3.8 GO:0021984 adenohypophysis development(GO:0021984)
0.2 6.5 GO:0050727 regulation of inflammatory response(GO:0050727)
0.2 2.0 GO:0051601 exocyst localization(GO:0051601)
0.2 3.5 GO:0042574 retinal metabolic process(GO:0042574)
0.2 20.2 GO:0071407 cellular response to organic cyclic compound(GO:0071407)
0.2 2.7 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.2 16.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.2 1.5 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 5.8 GO:0060037 pharyngeal system development(GO:0060037)
0.2 1.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 4.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 2.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.2 3.9 GO:0015701 bicarbonate transport(GO:0015701)
0.2 3.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 2.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 2.5 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.2 1.7 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.2 14.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 4.0 GO:0043588 skin development(GO:0043588)
0.2 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 2.8 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962) regulation of polysaccharide biosynthetic process(GO:0032885)
0.2 1.5 GO:0014028 notochord formation(GO:0014028)
0.2 9.4 GO:0060048 cardiac muscle contraction(GO:0060048)
0.2 3.5 GO:0006270 DNA replication initiation(GO:0006270)
0.2 4.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 1.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 5.5 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.2 2.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 12.4 GO:0031101 fin regeneration(GO:0031101)
0.2 8.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 1.3 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 4.2 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 1.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 5.8 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 4.3 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 0.6 GO:0015871 choline transport(GO:0015871)
0.1 6.6 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.1 0.4 GO:0043111 replication fork arrest(GO:0043111)
0.1 3.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 4.4 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 10.1 GO:0042113 B cell activation(GO:0042113)
0.1 2.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 4.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 2.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 2.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 8.2 GO:0009306 protein secretion(GO:0009306)
0.1 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 3.1 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 3.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 3.8 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 4.3 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.9 GO:0016203 muscle attachment(GO:0016203)
0.1 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 8.9 GO:0006364 rRNA processing(GO:0006364)
0.1 6.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 3.0 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.1 6.0 GO:0007338 single fertilization(GO:0007338)
0.1 1.6 GO:0009409 response to cold(GO:0009409) positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 4.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.7 GO:1905168 positive regulation of DNA recombination(GO:0045911) positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 2.1 GO:0006826 iron ion transport(GO:0006826)
0.1 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.6 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 2.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 17.1 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 1.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.3 GO:0016926 protein desumoylation(GO:0016926)
0.1 3.6 GO:0055088 lipid homeostasis(GO:0055088)
0.1 6.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.8 GO:0072663 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 10.2 GO:0061053 somite development(GO:0061053)
0.1 3.2 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 1.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.1 7.0 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 6.3 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 3.8 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.1 5.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 5.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 1.7 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 1.0 GO:0008272 sulfate transport(GO:0008272)
0.1 5.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.9 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 0.3 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 3.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 3.2 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.1 0.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.9 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 2.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 3.5 GO:0060215 primitive hemopoiesis(GO:0060215)
0.1 2.2 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.0 GO:0030259 lipid glycosylation(GO:0030259)
0.1 22.3 GO:0006412 translation(GO:0006412)
0.1 3.7 GO:0045765 regulation of angiogenesis(GO:0045765)
0.1 2.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 3.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 2.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 3.7 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 1.5 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 3.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.5 GO:0006857 oligopeptide transport(GO:0006857)
0.1 2.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 10.8 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.1 1.0 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.1 1.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 30.8 GO:0016567 protein ubiquitination(GO:0016567)
0.1 0.1 GO:0006458 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.1 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:0001776 leukocyte homeostasis(GO:0001776)
0.0 2.1 GO:0048278 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 4.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 15.0 GO:0006955 immune response(GO:0006955)
0.0 2.9 GO:0006400 tRNA modification(GO:0006400)
0.0 2.4 GO:0016573 histone acetylation(GO:0016573)
0.0 0.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 25.2 GO:0006508 proteolysis(GO:0006508)
0.0 5.6 GO:0061061 muscle structure development(GO:0061061)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 3.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.4 GO:0031333 negative regulation of protein complex assembly(GO:0031333)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 1.8 GO:0045165 cell fate commitment(GO:0045165)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 4.5 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.5 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0005577 fibrinogen complex(GO:0005577)
2.3 6.9 GO:0005960 glycine cleavage complex(GO:0005960)
2.1 6.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.8 5.3 GO:0070545 PeBoW complex(GO:0070545)
1.6 4.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.5 4.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
1.5 5.9 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
1.3 5.1 GO:0061689 tricellular tight junction(GO:0061689)
1.3 10.1 GO:0061700 GATOR2 complex(GO:0061700)
1.1 5.6 GO:0000811 GINS complex(GO:0000811)
1.0 16.5 GO:0000813 ESCRT I complex(GO:0000813)
0.9 7.5 GO:0001772 immunological synapse(GO:0001772)
0.9 6.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.9 1.7 GO:0032807 DNA ligase IV complex(GO:0032807)
0.8 23.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.8 10.3 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.8 3.8 GO:0055087 Ski complex(GO:0055087)
0.8 12.2 GO:0036038 MKS complex(GO:0036038)
0.8 6.8 GO:0071797 LUBAC complex(GO:0071797)
0.7 8.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.7 2.9 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.7 2.1 GO:0032301 MutSalpha complex(GO:0032301)
0.7 3.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.7 4.1 GO:0031262 Ndc80 complex(GO:0031262)
0.7 4.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.7 5.4 GO:0000796 condensin complex(GO:0000796)
0.7 2.0 GO:1990077 primosome complex(GO:1990077)
0.6 6.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.6 2.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.6 4.3 GO:0016234 inclusion body(GO:0016234)
0.6 1.8 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.6 4.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.6 10.8 GO:0016363 nuclear matrix(GO:0016363)
0.6 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 3.9 GO:0030914 STAGA complex(GO:0030914)
0.5 3.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 3.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.5 3.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 4.2 GO:0070552 BRISC complex(GO:0070552)
0.5 3.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.5 5.6 GO:0030904 retromer complex(GO:0030904)
0.5 7.1 GO:0000243 commitment complex(GO:0000243)
0.5 10.5 GO:0009925 basal plasma membrane(GO:0009925)
0.5 17.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 2.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.5 6.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 5.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 25.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 4.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 16.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 23.9 GO:0031901 early endosome membrane(GO:0031901)
0.3 32.1 GO:0005581 collagen trimer(GO:0005581)
0.3 3.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 6.4 GO:0097546 ciliary base(GO:0097546)
0.3 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 14.5 GO:0031941 filamentous actin(GO:0031941)
0.3 1.5 GO:0043198 ciliary rootlet(GO:0035253) dendritic shaft(GO:0043198)
0.3 37.7 GO:0005840 ribosome(GO:0005840)
0.3 2.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 3.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.7 GO:0016589 NURF complex(GO:0016589)
0.3 4.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 3.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 0.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 2.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 2.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.3 3.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 7.5 GO:0005839 proteasome core complex(GO:0005839)
0.3 3.9 GO:0070187 telosome(GO:0070187)
0.3 11.0 GO:0032587 ruffle membrane(GO:0032587)
0.3 28.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 30.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 10.5 GO:0005861 troponin complex(GO:0005861)
0.2 1.8 GO:0072487 MSL complex(GO:0072487)
0.2 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 12.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 18.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 23.4 GO:0016459 myosin complex(GO:0016459)
0.2 1.3 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 3.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 2.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 2.5 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.2 2.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 2.7 GO:0005579 membrane attack complex(GO:0005579)
0.2 2.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 19.5 GO:0005925 focal adhesion(GO:0005925)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 6.0 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.1 4.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.9 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 2.7 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 10.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 1.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 2.0 GO:0005771 multivesicular body(GO:0005771)
0.1 5.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.8 GO:0005869 dynactin complex(GO:0005869)
0.1 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 3.7 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.8 GO:0001650 fibrillar center(GO:0001650)
0.1 3.4 GO:0005643 nuclear pore(GO:0005643)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 65.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 7.8 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 5.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 25.6 GO:0005730 nucleolus(GO:0005730)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 3.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.7 GO:0031526 brush border membrane(GO:0031526)
0.1 21.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.2 GO:0097361 CIA complex(GO:0097361)
0.1 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 7.2 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 2.0 GO:0005657 replication fork(GO:0005657)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 16.3 GO:0005764 lysosome(GO:0005764)
0.1 2.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 17.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.7 GO:0043186 P granule(GO:0043186)
0.1 4.0 GO:0031301 integral component of organelle membrane(GO:0031301)
0.1 1.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 43.5 GO:0005615 extracellular space(GO:0005615)
0.0 13.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 5.3 GO:0000785 chromatin(GO:0000785)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0032806 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 16.3 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282) translation preinitiation complex(GO:0070993)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.6 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0005499 vitamin D binding(GO:0005499)
3.3 19.8 GO:0070330 aromatase activity(GO:0070330)
3.3 16.5 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
2.2 10.9 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
2.2 21.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
2.1 17.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.1 6.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.7 6.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.6 7.9 GO:0070573 metallodipeptidase activity(GO:0070573)
1.5 4.6 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.5 4.5 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
1.5 7.5 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
1.5 8.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.5 11.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.5 4.4 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
1.4 10.1 GO:0070728 leucine binding(GO:0070728)
1.4 4.2 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
1.4 8.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
1.4 4.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.3 11.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.2 6.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.2 3.7 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
1.2 4.8 GO:0008887 glycerate kinase activity(GO:0008887)
1.2 4.7 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
1.1 4.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.1 8.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.0 3.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.0 8.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
1.0 5.0 GO:0008097 5S rRNA binding(GO:0008097)
1.0 3.9 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
1.0 22.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.0 7.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.0 4.9 GO:0070412 R-SMAD binding(GO:0070412)
1.0 4.8 GO:0032052 bile acid binding(GO:0032052)
0.9 5.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.9 3.7 GO:0034511 U3 snoRNA binding(GO:0034511)
0.9 5.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.9 4.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.9 2.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.8 2.4 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.7 3.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.7 2.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.7 4.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.7 7.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 2.1 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.7 3.5 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 4.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.7 2.0 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.6 1.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.6 3.9 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.6 12.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.6 1.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.6 27.2 GO:0000049 tRNA binding(GO:0000049)
0.6 4.0 GO:0004630 phospholipase D activity(GO:0004630)
0.6 2.3 GO:0070052 collagen V binding(GO:0070052)
0.6 4.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.6 2.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.5 1.6 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5 4.8 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.5 5.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 4.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5 21.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.5 1.5 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.5 5.0 GO:0030332 cyclin binding(GO:0030332)
0.5 2.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.5 11.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.5 3.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.5 3.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.4 4.0 GO:0004359 glutaminase activity(GO:0004359)
0.4 8.0 GO:0002039 p53 binding(GO:0002039)
0.4 2.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 2.6 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.4 5.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.4 24.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 2.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 1.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.4 6.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4 10.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.4 2.0 GO:0043295 glutathione binding(GO:0043295)
0.4 2.0 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.4 1.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.4 1.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 2.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.4 6.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 28.3 GO:0003724 RNA helicase activity(GO:0003724)
0.3 3.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 3.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 5.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.3 5.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 3.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 61.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 1.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.6 GO:0050780 dopamine receptor binding(GO:0050780)
0.3 3.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 10.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 69.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 3.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 5.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.3 2.0 GO:0019809 spermidine binding(GO:0019809)
0.3 3.4 GO:0005158 insulin receptor binding(GO:0005158)
0.3 5.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 2.2 GO:0001032 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.3 1.9 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 9.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.3 3.3 GO:0008199 ferric iron binding(GO:0008199)
0.3 7.9 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.3 0.8 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.3 34.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 0.8 GO:0030623 U5 snRNA binding(GO:0030623)
0.3 28.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 0.8 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 2.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 3.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.2 2.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 3.8 GO:0030515 snoRNA binding(GO:0030515)
0.2 6.9 GO:0008483 transaminase activity(GO:0008483)
0.2 6.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 2.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 18.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 9.2 GO:0005109 frizzled binding(GO:0005109)
0.2 1.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.1 GO:0035173 histone kinase activity(GO:0035173)
0.2 2.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.9 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.2 20.6 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.7 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 1.2 GO:0004104 cholinesterase activity(GO:0004104)
0.2 0.8 GO:0070513 death domain binding(GO:0070513)
0.2 2.9 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 2.8 GO:2001069 glycogen binding(GO:2001069)
0.2 3.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 12.2 GO:0003823 antigen binding(GO:0003823)
0.2 25.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 2.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 3.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 3.1 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 2.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 2.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 1.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 3.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 12.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 5.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.6 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 3.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 7.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 3.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.9 GO:0004875 complement receptor activity(GO:0004875)
0.1 3.8 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.6 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 5.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.1 6.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 7.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 3.9 GO:0017069 snRNA binding(GO:0017069)
0.1 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.7 GO:0043566 structure-specific DNA binding(GO:0043566)
0.1 1.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 1.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 22.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 2.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.6 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 4.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 1.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 6.2 GO:0004386 helicase activity(GO:0004386)
0.1 0.7 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 5.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.6 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 1.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 4.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 13.2 GO:0008134 transcription factor binding(GO:0008134)
0.1 2.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 22.1 GO:0051015 actin filament binding(GO:0051015)
0.1 0.6 GO:0032977 membrane insertase activity(GO:0032977)
0.1 3.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0008126 acetylesterase activity(GO:0008126)
0.1 23.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.3 GO:0008430 selenium binding(GO:0008430)
0.1 2.9 GO:0019902 phosphatase binding(GO:0019902)
0.1 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 6.0 GO:0019955 cytokine binding(GO:0019955)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 3.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.0 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 4.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 2.9 GO:0019838 growth factor binding(GO:0019838)
0.0 2.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.2 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) ATP-dependent microtubule motor activity(GO:1990939)
0.0 1.3 GO:0050661 NADP binding(GO:0050661)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0003917 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0 6.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.5 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 42.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
1.0 43.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.8 6.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 15.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.5 5.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 6.2 PID CONE PATHWAY Visual signal transduction: Cones
0.4 11.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 10.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 20.5 PID P53 REGULATION PATHWAY p53 pathway
0.4 2.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 2.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 5.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 5.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 8.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 8.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 6.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 5.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 3.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 2.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 2.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 3.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 2.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 9.0 PID ATR PATHWAY ATR signaling pathway
0.3 6.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 9.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 3.1 PID IL1 PATHWAY IL1-mediated signaling events
0.2 7.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 8.2 PID AURORA B PATHWAY Aurora B signaling
0.2 3.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 4.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 2.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 3.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 4.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 3.4 PID MYC PATHWAY C-MYC pathway
0.2 1.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 2.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 4.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.2 PID AURORA A PATHWAY Aurora A signaling
0.1 2.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.0 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 11.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
2.3 9.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
2.2 24.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
2.1 10.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.9 20.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.2 26.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.0 5.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.8 4.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.8 5.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.7 5.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.7 13.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.7 24.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.6 7.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.6 17.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.6 15.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 6.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 11.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 6.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.5 8.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.5 7.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.5 10.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.5 3.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.4 46.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.4 5.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 5.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 2.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.4 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 4.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 6.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 10.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.4 10.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 5.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.3 5.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 6.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 2.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 2.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 2.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 3.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 3.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 7.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 3.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 10.4 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.2 6.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 0.9 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 11.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 5.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 4.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 5.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.9 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.1 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 6.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.6 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 2.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 4.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 4.3 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME DNA REPLICATION Genes involved in DNA Replication
0.1 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 5.1 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis