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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for barhl1a+barhl1b

Z-value: 1.70

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Transcription factors associated with barhl1a+barhl1b

Gene Symbol Gene ID Gene Info
barhl1b
ENSDARG00000019013 BarH-like homeobox 1b
barhl1a
ENSDARG00000035508 BarH-like homeobox 1a
barhl1a
ENSDARG00000110061 BarH-like homeobox 1a
barhl1a
ENSDARG00000112355 BarH-like homeobox 1a
barhl1b
ENSDARG00000113145 BarH-like homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barhl1adr11_v1_chr5_-_29750377_297503770.571.6e-09Click!
barhl1bdr11_v1_chr21_-_17482465_174824650.489.5e-07Click!

Activity profile of barhl1a+barhl1b motif

Sorted Z-values of barhl1a+barhl1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_34701848 14.44 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr14_-_1990290 11.60 ENSDART00000183382
pcdh2g5
protocadherin 2 gamma 5
chr8_+_25761654 10.54 ENSDART00000137899
ENSDART00000062403
tmem9
transmembrane protein 9
chr2_-_32387441 10.40 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr5_-_22082918 10.21 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr20_-_34801181 8.85 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr20_-_29475172 8.76 ENSDART00000183164
scg5
secretogranin V
chr3_+_35005730 8.74 ENSDART00000029451
prkcbb
protein kinase C, beta b
chr3_+_40170216 8.37 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr2_-_30460293 7.97 ENSDART00000113193
cbln2a
cerebellin 2a precursor
chr2_-_13216269 7.11 ENSDART00000149947
bcl2b
BCL2, apoptosis regulator b
chr23_+_35713557 6.83 ENSDART00000123518
tuba1c
tubulin, alpha 1c
chr13_-_9525527 6.78 ENSDART00000190618
CR848040.5

chr10_-_8033468 6.73 ENSDART00000140476
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr6_+_23752593 6.61 ENSDART00000164366
zgc:158654
zgc:158654
chr14_-_2202652 6.56 ENSDART00000171316
si:dkey-262j3.7
si:dkey-262j3.7
chr25_-_20666328 6.52 ENSDART00000098076
csk
C-terminal Src kinase
chr24_-_22756508 6.51 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr6_-_21873266 6.43 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
si:dkey-19e4.5
chr18_+_31410652 6.40 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr22_+_10215558 6.40 ENSDART00000063274
kctd6a
potassium channel tetramerization domain containing 6a
chr23_-_24682244 6.30 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr20_+_33294428 6.23 ENSDART00000024104
mycn
MYCN proto-oncogene, bHLH transcription factor
chr5_+_32141790 6.15 ENSDART00000041504
tescb
tescalcin b
chr19_-_10394931 6.11 ENSDART00000191549
zgc:194578
zgc:194578
chr18_+_7639401 6.06 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr14_+_50937757 6.05 ENSDART00000163865
rnf44
ring finger protein 44
chr15_+_32249062 6.05 ENSDART00000133867
ENSDART00000152545
ENSDART00000082315
ENSDART00000152513
ENSDART00000152139
arfip2a
ADP-ribosylation factor interacting protein 2a
chr10_-_8032885 6.00 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr17_+_24446353 5.96 ENSDART00000140467
ugp2b
UDP-glucose pyrophosphorylase 2b
chr18_-_14743659 5.92 ENSDART00000125979
tshz3a
teashirt zinc finger homeobox 3a
chr3_-_20106233 5.86 ENSDART00000145285
selenow2b
selenoprotein W, 2b
chr5_-_28915130 5.75 ENSDART00000078592
npdc1b
neural proliferation, differentiation and control, 1b
chr3_+_45365098 5.66 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr3_-_19368435 5.64 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr19_+_342094 5.61 ENSDART00000151013
ENSDART00000187622
ensaa
endosulfine alpha a
chr3_+_45364849 5.46 ENSDART00000153974
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr17_+_24445818 5.41 ENSDART00000139963
ugp2b
UDP-glucose pyrophosphorylase 2b
chr7_+_25000060 5.36 ENSDART00000039265
ENSDART00000141814
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr17_-_33716688 5.31 ENSDART00000043651
dnal1
dynein, axonemal, light chain 1
chr20_-_30938184 5.28 ENSDART00000147359
ENSDART00000062552
wtap
WT1 associated protein
chr10_+_21793670 5.14 ENSDART00000168918
pcdh1gc6
protocadherin 1 gamma c 6
chr7_+_40228422 5.12 ENSDART00000052222
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr17_+_24446533 5.09 ENSDART00000131417
ugp2b
UDP-glucose pyrophosphorylase 2b
chr2_+_16449627 5.02 ENSDART00000005381
zgc:110269
zgc:110269
chr2_-_37140423 4.99 ENSDART00000144220
tspan37
tetraspanin 37
chr10_-_11397590 4.99 ENSDART00000064212
srek1ip1
SREK1-interacting protein 1
chr16_-_31824525 4.98 ENSDART00000058737
cdc42l
cell division cycle 42, like
chr7_-_31921687 4.94 ENSDART00000146720
lin7c
lin-7 homolog C (C. elegans)
chr12_-_13318944 4.94 ENSDART00000152201
ENSDART00000041394
emc9
ER membrane protein complex subunit 9
chr14_-_14705335 4.87 ENSDART00000157392
ENSDART00000159456
ogt.1
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr13_-_28263856 4.87 ENSDART00000041036
ENSDART00000079806
smap1
small ArfGAP 1
chr19_+_29798064 4.86 ENSDART00000167803
ENSDART00000051804
marcksl1b
MARCKS-like 1b
chr13_+_46718518 4.85 ENSDART00000160401
ENSDART00000182884
tmem63ba
transmembrane protein 63Ba
chr19_-_33274978 4.82 ENSDART00000020301
ENSDART00000114714
fam92a1
family with sequence similarity 92, member A1
chr3_-_52683241 4.82 ENSDART00000155248
si:dkey-210j14.5
si:dkey-210j14.5
chr5_-_69437422 4.79 ENSDART00000073676
isca1
iron-sulfur cluster assembly 1
chr19_+_46237665 4.78 ENSDART00000159391
vps28
vacuolar protein sorting 28 (yeast)
chr6_-_55309190 4.78 ENSDART00000162117
ube2c
ubiquitin-conjugating enzyme E2C
chr25_-_11088839 4.78 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr23_+_19813677 4.76 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr3_-_27868183 4.72 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr8_-_10949847 4.71 ENSDART00000123209
pqlc2
PQ loop repeat containing 2
chr22_+_11756040 4.56 ENSDART00000105808
krt97
keratin 97
chr7_+_24645186 4.55 ENSDART00000150118
ENSDART00000150233
ENSDART00000087691
gba2
glucosidase, beta (bile acid) 2
chr3_+_31093455 4.52 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr23_-_25779995 4.51 ENSDART00000110670
si:dkey-21c19.3
si:dkey-21c19.3
chr22_-_9896180 4.44 ENSDART00000138343
znf990
zinc finger protein 990
chr19_-_13950231 4.43 ENSDART00000168665
sh3bgrl3
SH3 domain binding glutamate-rich protein like 3
chr23_+_27051919 4.41 ENSDART00000054237
ptges3a
prostaglandin E synthase 3a (cytosolic)
chr4_-_20051141 4.39 ENSDART00000066963
atp6v1f
ATPase H+ transporting V1 subunit F
chr19_-_21832441 4.34 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
mbpa
myelin basic protein a
chr25_-_31118923 4.29 ENSDART00000009126
ENSDART00000188286
kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr15_-_19128705 4.28 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr19_-_3488860 4.25 ENSDART00000172520
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr12_-_27031060 4.24 ENSDART00000076103
chmp2a
charged multivesicular body protein 2A
chr22_-_28079678 4.20 ENSDART00000169887
wu:fu71h07
wu:fu71h07
chr8_-_44223473 4.15 ENSDART00000098525
stx2b
syntaxin 2b
chr2_-_26469065 4.09 ENSDART00000099247
ENSDART00000099248
rabggtb
Rab geranylgeranyltransferase, beta subunit
chr2_-_13268556 4.08 ENSDART00000127693
ENSDART00000079757
vps4b
vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr1_+_34696503 4.05 ENSDART00000186106
CR339054.2

chr2_-_32826108 4.04 ENSDART00000098834
prpf4ba
pre-mRNA processing factor 4Ba
chr25_-_26753196 4.02 ENSDART00000155698
usp3
ubiquitin specific peptidase 3
chr17_+_22311413 3.98 ENSDART00000151929
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr22_-_10586191 3.97 ENSDART00000148418
si:dkey-42i9.16
si:dkey-42i9.16
chr22_-_33916620 3.96 ENSDART00000191276
CR974456.1

chr23_+_39854566 3.93 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr8_-_44223899 3.92 ENSDART00000143020
stx2b
syntaxin 2b
chr3_-_18274691 3.89 ENSDART00000161140
BX649434.3

chr19_+_29808471 3.88 ENSDART00000186428
hdac1
histone deacetylase 1
chr7_+_13418812 3.87 ENSDART00000191905
ENSDART00000091567
dagla
diacylglycerol lipase, alpha
chr13_-_24379271 3.86 ENSDART00000046360
rhoua
ras homolog family member Ua
chr23_-_12015139 3.85 ENSDART00000110627
ENSDART00000193988
ENSDART00000184528
si:dkey-178k16.1
si:dkey-178k16.1
chr4_+_20051478 3.82 ENSDART00000143642
lamtor4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr2_-_31614277 3.80 ENSDART00000137054
ENSDART00000131507
ENSDART00000137674
ENSDART00000147041
si:ch211-106h4.5
si:ch211-106h4.5
chr1_+_8601935 3.72 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr20_-_32110882 3.72 ENSDART00000030324
grm1a
glutamate receptor, metabotropic 1a
chr20_-_10120442 3.70 ENSDART00000144970
meis2b
Meis homeobox 2b
chr7_+_26466826 3.69 ENSDART00000058908
mpdu1b
mannose-P-dolichol utilization defect 1b
chr19_+_18739085 3.68 ENSDART00000188868
spaca4l
sperm acrosome associated 4 like
chr15_-_19669770 3.68 ENSDART00000152707
si:dkey-4p15.3
si:dkey-4p15.3
chr2_-_32825917 3.61 ENSDART00000180409
prpf4ba
pre-mRNA processing factor 4Ba
chr13_+_15656042 3.58 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr4_+_30363474 3.51 ENSDART00000168421
si:dkey-199m13.7
si:dkey-199m13.7
chr3_-_61387273 3.46 ENSDART00000156479
znf1143
zinc finger protein 1143
chr3_-_15352303 3.44 ENSDART00000104338
ENSDART00000145919
ENSDART00000132135
pitpnbl
phosphatidylinositol transfer protein, beta, like
chr9_-_33477588 3.43 ENSDART00000144150
caska
calcium/calmodulin-dependent serine protein kinase a
chr3_-_32859335 3.41 ENSDART00000158916
si:dkey-16l2.20
si:dkey-16l2.20
chr25_+_17590095 3.41 ENSDART00000009767
vac14
vac14 homolog (S. cerevisiae)
chr7_+_34236238 3.40 ENSDART00000052474
tipin
timeless interacting protein
chr11_+_6136220 3.39 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr18_+_7150144 3.38 ENSDART00000114690
vwf
von Willebrand factor
chr17_-_14451718 3.37 ENSDART00000039438
jkamp
jnk1/mapk8 associated membrane protein
chr21_-_2162850 3.37 ENSDART00000159731
gb:ai877918
expressed sequence AI877918
chr20_-_32148901 3.35 ENSDART00000153405
ENSDART00000048537
ENSDART00000152984
cep57l1
centrosomal protein 57, like 1
chr25_-_20268027 3.34 ENSDART00000138763
dnajb9a
DnaJ (Hsp40) homolog, subfamily B, member 9a
chr3_+_54761569 3.32 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
si:ch211-74m13.1
chr8_+_25190023 3.31 ENSDART00000047528
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr3_-_52644737 3.30 ENSDART00000126180
si:dkey-210j14.3
si:dkey-210j14.3
chr16_+_43347966 3.28 ENSDART00000171308
zmp:0000000930
zmp:0000000930
chr24_-_41797681 3.28 ENSDART00000169643
arhgap28
Rho GTPase activating protein 28
chr4_+_19535946 3.28 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
lrrc4.1
leucine rich repeat containing 4.1
chr15_-_6976851 3.25 ENSDART00000158474
ENSDART00000168943
ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr2_-_38080075 3.24 ENSDART00000056544
tox4a
TOX high mobility group box family member 4 a
chr25_-_24202576 3.23 ENSDART00000048507
uevld
UEV and lactate/malate dehyrogenase domains
chr2_-_10338759 3.22 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr6_+_296130 3.20 ENSDART00000073985
rbfox2
RNA binding fox-1 homolog 2
chr13_+_22717939 3.18 ENSDART00000188288
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr3_-_32590164 3.16 ENSDART00000151151
tspan4b
tetraspanin 4b
chr3_+_32714157 3.16 ENSDART00000131774
setd1a
SET domain containing 1A
chr3_+_22442445 3.14 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr1_+_29267841 3.12 ENSDART00000085648
lig4
ligase IV, DNA, ATP-dependent
chr16_-_35415004 3.12 ENSDART00000170401
ENSDART00000157832
ENSDART00000170048
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_-_33618612 3.11 ENSDART00000033980
lims1
LIM and senescent cell antigen-like domains 1
chr3_-_16110100 3.09 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr3_-_36210344 3.08 ENSDART00000025326
csnk1da
casein kinase 1, delta a
chr22_-_21314821 3.07 ENSDART00000105546
ENSDART00000135388
cks2
CDC28 protein kinase regulatory subunit 2
chr13_+_9612395 3.06 ENSDART00000136689
ENSDART00000138362
slf2
SMC5-SMC6 complex localization factor 2
chr1_+_52481332 3.05 ENSDART00000074231
cldnd1b
claudin domain containing 1b
chr16_+_9400661 3.04 ENSDART00000146174
ice1
KIAA0947-like (H. sapiens)
chr5_-_35252761 3.04 ENSDART00000051278
tnpo1
transportin 1
chr17_+_24597001 3.02 ENSDART00000191834
rlf
rearranged L-myc fusion
chr9_-_34300707 3.02 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr5_-_32890807 3.02 ENSDART00000007512
pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr12_-_7655322 2.97 ENSDART00000181162
ank3b
ankyrin 3b
chr19_+_14921000 2.97 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr16_+_49601838 2.96 ENSDART00000168570
ENSDART00000159236
si:dkey-82o10.4
si:dkey-82o10.4
chr4_-_75172216 2.94 ENSDART00000127522
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr3_+_13842554 2.93 ENSDART00000162317
ENSDART00000158068
ilf3b
interleukin enhancer binding factor 3b
chr5_+_57480014 2.90 ENSDART00000135520
si:ch211-202f5.3
si:ch211-202f5.3
chr23_+_28582865 2.88 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr16_+_25407021 2.86 ENSDART00000187489
ENSDART00000086333
jarid2a
jumonji, AT rich interactive domain 2a
chr23_+_42272588 2.85 ENSDART00000164907
CABZ01065131.1

chr21_-_25801956 2.84 ENSDART00000101219
mettl27
methyltransferase like 27
chr3_+_26019426 2.83 ENSDART00000135389
ENSDART00000182411
foxred2
FAD-dependent oxidoreductase domain containing 2
chr18_+_17663898 2.82 ENSDART00000021213
cpne2
copine II
chr8_-_7847921 2.81 ENSDART00000188094
zgc:113363
zgc:113363
chr12_+_16087077 2.81 ENSDART00000141898
znf281b
zinc finger protein 281b
chr9_+_23748342 2.80 ENSDART00000019053
faima
Fas apoptotic inhibitory molecule a
chr11_+_37612214 2.79 ENSDART00000172899
ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr12_+_28910762 2.77 ENSDART00000076342
ENSDART00000160939
ENSDART00000076572
rnf40
ring finger protein 40
chr24_-_6345647 2.77 ENSDART00000108994
zgc:174877
zgc:174877
chr13_-_11072964 2.73 ENSDART00000135989
cep170aa
centrosomal protein 170Aa
chr14_+_8947282 2.73 ENSDART00000047993
rps6kal
ribosomal protein S6 kinase a, like
chr12_-_20409794 2.73 ENSDART00000077936
lcmt1
leucine carboxyl methyltransferase 1
chr5_+_53580846 2.72 ENSDART00000184967
ENSDART00000161751
taf6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_+_31904836 2.72 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr24_-_11057305 2.72 ENSDART00000186494
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr6_+_9107063 2.71 ENSDART00000083820
vps16
vacuolar protein sorting protein 16
chr17_+_21760032 2.71 ENSDART00000190425
ikzf5
IKAROS family zinc finger 5
chr17_+_21817382 2.70 ENSDART00000079011
ENSDART00000189387
ikzf5
IKAROS family zinc finger 5
chr5_+_57714902 2.69 ENSDART00000182860
ufc1
ubiquitin-fold modifier conjugating enzyme 1
chr3_+_27798094 2.69 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr1_+_19433004 2.69 ENSDART00000133959
clockb
clock circadian regulator b
chr4_+_15006217 2.69 ENSDART00000090837
zc3hc1
zinc finger, C3HC-type containing 1
chr5_-_42180205 2.67 ENSDART00000145247
fam222ba
family with sequence similarity 222, member Ba
chr2_+_15776156 2.63 ENSDART00000190795
vav3b
vav 3 guanine nucleotide exchange factor b
chr12_+_18906939 2.59 ENSDART00000186074
josd1
Josephin domain containing 1
chr1_-_31515746 2.59 ENSDART00000190886
cenpk
centromere protein K
chr7_-_40630698 2.59 ENSDART00000134547
ube3c
ubiquitin protein ligase E3C
chr2_+_32826235 2.58 ENSDART00000143127
si:dkey-154p10.3
si:dkey-154p10.3
chr16_-_11779508 2.58 ENSDART00000136329
ENSDART00000060145
ENSDART00000141101
pafah1b3
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
chr7_+_21887307 2.56 ENSDART00000052871
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr5_+_36900157 2.55 ENSDART00000183533
ENSDART00000051184
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr23_+_24955394 2.54 ENSDART00000142124
nol9
nucleolar protein 9
chr13_+_9368621 2.53 ENSDART00000109126
alms1
Alstrom syndrome protein 1
chr14_+_21820034 2.51 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr1_+_26105141 2.49 ENSDART00000102379
ENSDART00000127154
toporsa
topoisomerase I binding, arginine/serine-rich a
chr24_+_12075009 2.48 ENSDART00000181141
ccr9b
chemokine (C-C motif) receptor 9b
chr21_-_30181732 2.47 ENSDART00000015636
hnrnph1l
heterogeneous nuclear ribonucleoprotein H1, like
chr12_+_18681477 2.47 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr14_-_2206476 2.46 ENSDART00000081870
pcdh2ab6
protocadherin 2 alpha b 6
chr8_-_16674584 2.43 ENSDART00000100727
osbpl9
oxysterol binding protein-like 9
chr7_+_24081167 2.43 ENSDART00000141749
acin1b
apoptotic chromatin condensation inducer 1b
chr7_-_7972445 2.43 ENSDART00000182687
ENSDART00000191946
si:cabz01030277.1
si:cabz01030277.1
chr12_+_5209822 2.42 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr3_+_7040363 2.41 ENSDART00000157805
BX000701.2

chr22_-_10055744 2.41 ENSDART00000143686
si:ch211-222k6.2
si:ch211-222k6.2
chr10_-_42108137 2.40 ENSDART00000132976
ess2
ess-2 splicing factor homolog
chr19_-_20777351 2.40 ENSDART00000019206
ngly1
N-glycanase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of barhl1a+barhl1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
2.8 11.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
1.5 4.6 GO:0006678 glucosylceramide metabolic process(GO:0006678)
1.3 6.5 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.2 4.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.1 5.7 GO:1901207 regulation of heart looping(GO:1901207)
1.1 3.4 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
1.0 3.0 GO:0006272 leading strand elongation(GO:0006272)
1.0 4.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.0 8.8 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
1.0 5.9 GO:0010269 response to selenium ion(GO:0010269)
1.0 3.9 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.9 4.7 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.9 6.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.9 12.7 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.9 4.5 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.9 5.3 GO:0080009 mRNA methylation(GO:0080009)
0.8 4.0 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.8 2.3 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.8 3.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.7 3.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.7 2.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.7 2.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.7 4.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.7 3.4 GO:0043111 replication fork arrest(GO:0043111)
0.6 8.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 3.0 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.6 4.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.6 2.9 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.6 3.4 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.6 3.9 GO:0033687 osteoblast proliferation(GO:0033687)
0.5 4.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.5 3.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 2.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.5 1.9 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.5 2.4 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.4 1.8 GO:0021543 substrate-dependent cell migration(GO:0006929) pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.4 2.2 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.4 3.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 6.1 GO:0016926 protein desumoylation(GO:0016926)
0.4 5.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.4 4.3 GO:0051382 kinetochore assembly(GO:0051382)
0.3 10.0 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.3 1.0 GO:0000423 macromitophagy(GO:0000423)
0.3 1.0 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.3 2.7 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.3 4.4 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) chaperone-mediated protein complex assembly(GO:0051131)
0.3 4.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.3 1.4 GO:0002159 desmosome assembly(GO:0002159)
0.3 0.8 GO:0071514 genetic imprinting(GO:0071514)
0.3 6.0 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.3 2.8 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.3 1.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 0.8 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 4.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 1.2 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 3.7 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.2 2.7 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.2 8.4 GO:0048665 neuron fate specification(GO:0048665)
0.2 8.1 GO:0007340 acrosome reaction(GO:0007340)
0.2 3.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 2.4 GO:0006517 protein deglycosylation(GO:0006517)
0.2 15.6 GO:0044839 cell cycle G2/M phase transition(GO:0044839)
0.2 0.7 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 2.6 GO:0009648 photoperiodism(GO:0009648)
0.2 14.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.2 8.8 GO:0046883 regulation of hormone secretion(GO:0046883)
0.2 2.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 2.3 GO:0045453 bone resorption(GO:0045453)
0.2 2.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 4.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 2.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 3.3 GO:0051098 regulation of binding(GO:0051098)
0.2 2.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 1.4 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.2 1.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.7 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.2 5.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.2 2.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 3.8 GO:0032008 positive regulation of TOR signaling(GO:0032008) cellular response to amino acid stimulus(GO:0071230)
0.2 8.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 2.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 4.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 2.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.7 GO:0016574 histone ubiquitination(GO:0016574)
0.1 3.7 GO:0007286 spermatid development(GO:0007286)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 3.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 4.1 GO:0042476 odontogenesis(GO:0042476)
0.1 0.7 GO:0070254 mucus secretion(GO:0070254)
0.1 0.4 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 2.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 27.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.7 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 3.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.3 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 3.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 11.5 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.8 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.2 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 1.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 2.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 2.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.5 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 2.2 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 1.3 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 1.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 0.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 3.4 GO:0015914 phospholipid transport(GO:0015914)
0.1 3.3 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 8.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 2.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 6.4 GO:0051260 protein homooligomerization(GO:0051260)
0.1 2.1 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 1.9 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 2.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.9 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 2.7 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 4.9 GO:0003407 neural retina development(GO:0003407)
0.0 1.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851) calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 2.9 GO:0051607 defense response to virus(GO:0051607)
0.0 1.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 2.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 2.1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 10.3 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 4.4 GO:0001947 heart looping(GO:0001947)
0.0 1.7 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 2.6 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 2.1 GO:0003341 cilium movement(GO:0003341)
0.0 1.9 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.2 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 2.3 GO:0060326 cell chemotaxis(GO:0060326)
0.0 2.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 5.8 GO:0008380 RNA splicing(GO:0008380)
0.0 1.3 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.2 GO:0016358 dendrite development(GO:0016358)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.9 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 3.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 1.5 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 1.6 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 1.7 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 7.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 2.3 GO:0051604 protein maturation(GO:0051604)
0.0 1.1 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 1.0 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 1.5 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 2.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 2.8 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 1.8 GO:0006397 mRNA processing(GO:0006397)
0.0 2.6 GO:0016042 lipid catabolic process(GO:0016042)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 27.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.5 5.8 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
1.3 5.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.2 4.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.1 3.4 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
1.0 3.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.0 4.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.8 3.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.8 3.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 3.4 GO:0031298 replication fork protection complex(GO:0031298)
0.6 3.8 GO:0071986 Ragulator complex(GO:0071986)
0.6 1.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.6 4.3 GO:0001650 fibrillar center(GO:0001650)
0.5 2.7 GO:0033263 CORVET complex(GO:0033263)
0.5 2.6 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.4 4.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 1.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.4 2.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 3.4 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 1.7 GO:0033503 HULC complex(GO:0033503)
0.3 8.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 1.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 4.3 GO:0043209 myelin sheath(GO:0043209)
0.3 4.2 GO:0000815 ESCRT III complex(GO:0000815)
0.3 6.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 4.8 GO:0000813 ESCRT I complex(GO:0000813)
0.3 1.7 GO:0070695 FHF complex(GO:0070695)
0.3 8.4 GO:0031594 neuromuscular junction(GO:0031594)
0.3 1.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 2.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 4.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 2.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 3.1 GO:0014704 intercalated disc(GO:0014704)
0.2 4.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 0.9 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 3.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 2.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 1.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 1.5 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.2 15.7 GO:0030141 secretory granule(GO:0030141)
0.2 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.2 6.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 6.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.4 GO:0000124 SAGA complex(GO:0000124)
0.1 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 5.0 GO:0030496 midbody(GO:0030496)
0.1 1.7 GO:0015030 Cajal body(GO:0015030)
0.1 3.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 6.8 GO:0005814 centriole(GO:0005814)
0.1 4.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.4 GO:0030057 desmosome(GO:0030057)
0.1 3.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 3.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 7.1 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1 3.1 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.3 GO:0030018 Z disc(GO:0030018)
0.1 5.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 4.0 GO:0042383 sarcolemma(GO:0042383)
0.1 0.7 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 2.0 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 2.6 GO:0030286 dynein complex(GO:0030286)
0.0 4.4 GO:0005882 intermediate filament(GO:0005882)
0.0 11.1 GO:0005730 nucleolus(GO:0005730)
0.0 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 6.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.1 GO:0005925 focal adhesion(GO:0005925)
0.0 7.6 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 2.6 GO:0005813 centrosome(GO:0005813)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.6 GO:0030425 dendrite(GO:0030425)
0.0 0.2 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 2.7 GO:0000785 chromatin(GO:0000785)
0.0 11.1 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.2 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 73.5 GO:0005634 nucleus(GO:0005634)
0.0 14.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.7 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 2.8 GO:0005768 endosome(GO:0005768)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
2.8 11.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
2.1 8.3 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
1.3 3.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.2 8.7 GO:0035173 histone kinase activity(GO:0035173)
1.2 4.9 GO:0097016 L27 domain binding(GO:0097016)
1.1 4.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.0 4.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.0 3.0 GO:0038046 enkephalin receptor activity(GO:0038046)
0.9 6.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.9 2.7 GO:0071568 UFM1 transferase activity(GO:0071568)
0.9 6.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.8 12.7 GO:0051117 ATPase binding(GO:0051117)
0.8 4.9 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.8 2.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.7 5.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.7 5.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.7 6.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.6 2.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 3.7 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.5 3.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 3.7 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.4 5.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 1.2 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.4 2.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.4 4.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 2.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.4 6.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.4 5.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.4 3.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 2.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 4.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 2.7 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.3 2.9 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 4.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.9 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 2.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 3.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 4.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 3.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 3.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 5.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 3.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 2.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 4.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 2.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 4.1 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.2 2.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 3.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 2.0 GO:0022839 ion gated channel activity(GO:0022839)
0.2 2.9 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 3.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 1.9 GO:1990239 steroid hormone binding(GO:1990239)
0.2 10.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.0 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 4.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 4.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 7.6 GO:0031491 nucleosome binding(GO:0031491)
0.1 4.3 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 3.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 6.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 4.3 GO:0019003 GDP binding(GO:0019003)
0.1 1.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 3.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 7.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 6.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 11.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.3 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 7.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.4 GO:0015026 coreceptor activity(GO:0015026)
0.1 2.2 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.5 GO:0031267 small GTPase binding(GO:0031267)
0.1 7.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 2.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 2.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 7.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 17.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 4.6 GO:0030276 clathrin binding(GO:0030276)
0.0 5.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 3.8 GO:0060090 binding, bridging(GO:0060090)
0.0 5.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 32.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 9.9 GO:0003924 GTPase activity(GO:0003924)
0.0 10.0 GO:0015631 tubulin binding(GO:0015631)
0.0 2.8 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.7 GO:0019901 protein kinase binding(GO:0019901)
0.0 5.4 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 5.3 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 5.4 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.8 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.5 GO:0015103 inorganic anion transmembrane transporter activity(GO:0015103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 4.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 3.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 10.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.2 4.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 10.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 5.9 PID ATR PATHWAY ATR signaling pathway
0.2 4.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.5 PID ATM PATHWAY ATM pathway
0.1 1.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.7 4.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.5 3.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.5 13.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 6.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 3.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 2.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 4.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 4.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 3.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 5.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 3.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 3.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 3.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 2.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 1.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 3.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 2.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 4.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 3.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 2.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 5.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 5.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.5 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 1.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 3.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C