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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for barx2

Z-value: 1.24

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Transcription factors associated with barx2

Gene Symbol Gene ID Gene Info
barx2
ENSDARG00000041098 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barx2dr11_v1_chr18_+_47313899_473138990.047.2e-01Click!

Activity profile of barx2 motif

Sorted Z-values of barx2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_9669717 27.86 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr11_+_30057762 21.46 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr22_-_13851297 19.11 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr16_+_5774977 16.18 ENSDART00000134202
ccka
cholecystokinin a
chr2_-_44280061 15.65 ENSDART00000136818
mpz
myelin protein zero
chr23_+_40460333 14.42 ENSDART00000184658
soga3b
SOGA family member 3b
chr8_+_31717175 14.31 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr9_-_9348058 13.93 ENSDART00000132257
zgc:113337
zgc:113337
chr15_-_44512461 12.45 ENSDART00000155456
gria4a
glutamate receptor, ionotropic, AMPA 4a
chr25_+_37126921 11.90 ENSDART00000124331
si:ch1073-174d20.1
si:ch1073-174d20.1
chr25_-_19420949 11.70 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr12_-_10300101 11.65 ENSDART00000126428
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr2_+_20430366 11.60 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr6_-_11768198 11.47 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr16_+_46111849 11.46 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr5_+_63668735 11.06 ENSDART00000134261
ENSDART00000097330
dnm1b
dynamin 1b
chr8_+_31716872 10.79 ENSDART00000161121
oxct1a
3-oxoacid CoA transferase 1a
chr13_-_29420885 10.17 ENSDART00000024225
chata
choline O-acetyltransferase a
chr18_+_24919614 9.92 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr17_-_20717845 9.66 ENSDART00000150037
ank3b
ankyrin 3b
chr16_-_28856112 9.58 ENSDART00000078543
syt11b
synaptotagmin XIb
chr20_+_41756996 9.55 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr23_-_26521970 9.34 ENSDART00000143712
si:dkey-205h13.1
si:dkey-205h13.1
chr21_-_20939488 9.34 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr19_-_26869103 9.13 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr2_-_30784198 8.90 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr12_+_18578597 8.83 ENSDART00000134944
grid2ipb
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr16_-_25568512 8.59 ENSDART00000149411
atxn1b
ataxin 1b
chr9_-_42418470 8.46 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr11_+_30663300 8.38 ENSDART00000161662
ttbk1a
tau tubulin kinase 1a
chr16_+_54209504 8.32 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr1_-_19502322 8.31 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr6_-_40744720 8.19 ENSDART00000154916
ENSDART00000186922
p4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr18_-_48983690 8.09 ENSDART00000182359
FO681288.3

chr5_+_4054704 7.94 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr13_+_7292061 7.92 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr4_-_2219705 7.88 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr1_-_50859053 7.71 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr12_+_4971515 7.64 ENSDART00000161076
arhgap27
Rho GTPase activating protein 27
chr12_+_1139690 7.57 ENSDART00000160442
CABZ01072885.1

chr6_-_6487876 7.55 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr7_-_25895189 7.37 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr16_-_12173554 7.29 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr3_-_20040636 7.24 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr5_-_6377865 7.12 ENSDART00000031775
zgc:73226
zgc:73226
chr4_-_5019113 6.91 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr10_-_21054059 6.75 ENSDART00000139733
pcdh1a
protocadherin 1a
chr6_-_30210378 6.72 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr21_-_39177564 6.69 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr7_-_49594995 6.68 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr3_+_46459540 6.54 ENSDART00000188150
si:ch211-66e2.5
si:ch211-66e2.5
chr24_-_28437833 6.47 ENSDART00000125412
fbxo45
F-box protein 45
chr15_-_755023 6.38 ENSDART00000155594
znf1011
zinc finger protein 1011
chr6_-_29305132 6.18 ENSDART00000132456
bivm
basic, immunoglobulin-like variable motif containing
chr24_+_36204028 6.04 ENSDART00000063832
ENSDART00000155260
rbbp8
retinoblastoma binding protein 8
chr15_+_15856178 6.03 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr9_+_7998794 6.02 ENSDART00000138167
myo16
myosin XVI
chr24_-_15131831 5.92 ENSDART00000028410
cd226
CD226 molecule
chr25_-_27722614 5.84 ENSDART00000190154
zgc:153935
zgc:153935
chr21_+_13387965 5.82 ENSDART00000134347
zgc:113162
zgc:113162
chr22_+_18816662 5.67 ENSDART00000132476
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr17_-_2386569 5.64 ENSDART00000121614
PLCB2
phospholipase C beta 2
chr22_-_26865361 5.63 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr8_-_14375890 5.55 ENSDART00000090306
xpr1a
xenotropic and polytropic retrovirus receptor 1a
chr15_+_15516612 5.51 ENSDART00000016024
traf4a
tnf receptor-associated factor 4a
chr25_+_16116740 5.48 ENSDART00000139778
far1
fatty acyl CoA reductase 1
chr4_+_4849789 5.47 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr23_+_4253957 5.44 ENSDART00000008761
arl6ip5b
ADP-ribosylation factor-like 6 interacting protein 5b
chr9_+_54039006 5.44 ENSDART00000112441
tlr7
toll-like receptor 7
chr23_+_17899226 5.36 ENSDART00000079487
CU234171.1

chr7_+_20629411 5.35 ENSDART00000173710
si:dkey-19b23.15
si:dkey-19b23.15
chr5_-_14373662 5.28 ENSDART00000183694
tet3
tet methylcytosine dioxygenase 3
chr2_+_11923615 5.20 ENSDART00000126118
trove2
TROVE domain family, member 2
chr4_+_17279966 5.19 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr24_+_28953089 5.18 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr6_+_13933464 5.08 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr20_+_19512727 5.07 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr21_+_13383413 4.99 ENSDART00000151345
zgc:113162
zgc:113162
chr5_+_65536095 4.98 ENSDART00000189898
si:dkey-21e5.1
si:dkey-21e5.1
chr7_+_19552381 4.94 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr2_-_23004286 4.94 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr5_-_66702479 4.92 ENSDART00000129197
mn1b
meningioma 1b
chr5_+_63302660 4.90 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr16_+_40024883 4.83 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr7_-_48805181 4.83 ENSDART00000015884
mfge8a
milk fat globule-EGF factor 8 protein a
chr2_-_3678029 4.82 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr17_-_11329959 4.75 ENSDART00000015418
irf2bpl
interferon regulatory factor 2 binding protein-like
chr21_-_28340977 4.73 ENSDART00000141629
nrxn2a
neurexin 2a
chr18_-_30020879 4.68 ENSDART00000162086
si:ch211-220f16.2
si:ch211-220f16.2
chr14_-_470505 4.63 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr20_+_34717403 4.57 ENSDART00000034252
pnocb
prepronociceptin b
chr20_+_40457599 4.57 ENSDART00000017553
serinc1
serine incorporator 1
chr25_-_29988352 4.56 ENSDART00000067059
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr8_-_50888806 4.53 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr16_-_35329803 4.52 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr1_-_22512063 4.44 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr3_-_48716422 4.43 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr16_+_22761846 4.40 ENSDART00000193028
CR854942.1

chr1_+_40107811 4.39 ENSDART00000113954
si:ch211-113e8.11
si:ch211-113e8.11
chr11_+_29770966 4.39 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr3_+_62339264 4.38 ENSDART00000174569
BX470259.3

chr16_-_44945224 4.37 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr5_-_12407194 4.37 ENSDART00000125291
ksr2
kinase suppressor of ras 2
chr3_+_60721342 4.28 ENSDART00000157772
foxj1a
forkhead box J1a
chr23_-_36446307 4.27 ENSDART00000136623
zgc:174906
zgc:174906
chr13_-_12494575 4.24 ENSDART00000137761
si:dkey-20i10.7
si:dkey-20i10.7
chr11_+_11267493 4.23 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr10_-_7386475 4.23 ENSDART00000167963
nrg1
neuregulin 1
chr25_-_25058508 4.20 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr3_+_24190207 4.19 ENSDART00000034762
prr15la
proline rich 15-like a
chr22_+_1700552 4.15 ENSDART00000166185
znf1154
zinc finger protein 1154
chr6_-_40466861 4.14 ENSDART00000062724
crbn
cereblon
chr15_-_9257136 4.14 ENSDART00000187901
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr10_+_42733210 4.10 ENSDART00000189832
CABZ01063556.1

chr12_+_8168272 4.08 ENSDART00000054092
arid5b
AT-rich interaction domain 5B
chr3_+_24537023 4.05 ENSDART00000077702
sp100.1
SP110 nuclear body protein, tandem duplicate 1
chr2_+_57848844 4.01 ENSDART00000037279
plekhj1
pleckstrin homology domain containing, family J member 1
chr18_-_215698 4.01 ENSDART00000147430
tarsl2
threonyl-tRNA synthetase-like 2
chr1_+_51312752 4.00 ENSDART00000063938
mast1a
microtubule associated serine/threonine kinase 1a
chr20_-_53078607 3.94 ENSDART00000163494
ENSDART00000191730
CABZ01066813.1

chr22_+_2769236 3.90 ENSDART00000141836
si:dkey-20i20.10
si:dkey-20i20.10
chr1_+_45663727 3.90 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trappc5
trafficking protein particle complex 5
chr12_-_35885349 3.89 ENSDART00000085662
cep131
centrosomal protein 131
chr14_-_16082806 3.88 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr2_-_42065069 3.86 ENSDART00000140188
cspp1b
centrosome and spindle pole associated protein 1b
chr23_+_7710447 3.84 ENSDART00000168199
kif3b
kinesin family member 3B
chr6_+_49551614 3.83 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr10_-_36927594 3.80 ENSDART00000162046
sez6a
seizure related 6 homolog a
chr17_-_39772999 3.80 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr9_+_2574122 3.77 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr23_+_32021803 3.58 ENSDART00000012963
trappc6b
trafficking protein particle complex 6b
chr17_-_16422654 3.58 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr13_+_15656042 3.56 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr7_-_40145097 3.54 ENSDART00000173634
wdr60
WD repeat domain 60
chr1_-_15797663 3.53 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr17_+_41992054 3.52 ENSDART00000182878
ENSDART00000111537
kiz
kizuna centrosomal protein
chr7_-_71829649 3.51 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr1_-_22757145 3.44 ENSDART00000134719
prom1b
prominin 1 b
chr10_+_45089820 3.44 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr1_+_513986 3.44 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr16_+_28994709 3.43 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr3_+_57268363 3.42 ENSDART00000180725
TMEM235 (1 of many)
transmembrane protein 235
chr21_+_38732945 3.40 ENSDART00000076157
rab24
RAB24, member RAS oncogene family
chr18_-_30021479 3.35 ENSDART00000144562
si:ch211-220f16.2
si:ch211-220f16.2
chr21_+_27513859 3.33 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr10_+_15967643 3.32 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr16_-_12173399 3.31 ENSDART00000142574
clstn3
calsyntenin 3
chr8_+_7097740 3.30 ENSDART00000159670
abtb1
ankyrin repeat and BTB (POZ) domain containing 1
chr11_-_1509773 3.30 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr3_+_62205858 3.29 ENSDART00000126807
zgc:173575
zgc:173575
chr5_-_37881345 3.29 ENSDART00000084819
arhgap35b
Rho GTPase activating protein 35b
chr22_-_17844117 3.27 ENSDART00000159363
BX908731.1

chr8_+_44722140 3.24 ENSDART00000163381
elmod3
ELMO/CED-12 domain containing 3
chr11_+_42726712 3.23 ENSDART00000028955
tdrd3
tudor domain containing 3
chr3_-_26806032 3.22 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr10_-_29236860 3.21 ENSDART00000111620
ccdc83
coiled-coil domain containing 83
chr8_+_23521974 3.20 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr1_+_55293424 3.16 ENSDART00000152464
zgc:172106
zgc:172106
chr12_+_48480632 3.14 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr2_+_7295515 3.14 ENSDART00000152987
si:dkeyp-106c3.1
si:dkeyp-106c3.1
chr4_+_2482046 3.14 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr1_+_38775041 3.12 ENSDART00000110824
wdr17
WD repeat domain 17
chr2_-_33645411 3.10 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr21_+_723998 3.10 ENSDART00000160956
oaz1b
ornithine decarboxylase antizyme 1b
chr3_+_62271320 3.08 ENSDART00000132197
BX470259.2

chr5_-_41494831 3.07 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr1_+_6862917 3.04 ENSDART00000182953
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr10_-_7857494 3.03 ENSDART00000143215
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr11_+_31323746 3.02 ENSDART00000180220
ENSDART00000189937
sipa1l2
signal-induced proliferation-associated 1 like 2
chr22_+_30496360 3.01 ENSDART00000189145
BX649490.4

chr16_+_25074029 2.98 ENSDART00000155465
si:dkeyp-84f3.9
si:dkeyp-84f3.9
chr16_-_22781446 2.92 ENSDART00000144107
lenep
lens epithelial protein
chr1_+_11977426 2.86 ENSDART00000103399
tspan5b
tetraspanin 5b
chr24_+_12983434 2.85 ENSDART00000145214
ENSDART00000146911
ENSDART00000066700
eloca
elongin C paralog a
chr21_-_2232640 2.85 ENSDART00000157754
zgc:113343
zgc:113343
chr18_+_17725410 2.84 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr12_+_14556092 2.84 ENSDART00000115237
becn1
beclin 1, autophagy related
chr13_-_38730267 2.83 ENSDART00000157524
lmbrd1
LMBR1 domain containing 1
chr7_+_19528265 2.82 ENSDART00000005326
ttc5
tetratricopeptide repeat domain 5
chr24_-_7995960 2.80 ENSDART00000186594
bloc1s5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr15_-_40267485 2.79 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr24_-_29586082 2.79 ENSDART00000136763
vav3a
vav 3 guanine nucleotide exchange factor a
chr19_-_3931917 2.78 ENSDART00000162532
map7d1b
MAP7 domain containing 1b
chr23_+_36460239 2.77 ENSDART00000172441
lima1a
LIM domain and actin binding 1a
chr23_-_36303216 2.77 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr15_-_14552101 2.77 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr16_-_36748374 2.72 ENSDART00000133310
pik3r4
phosphoinositide-3-kinase, regulatory subunit 4
chr17_+_49281597 2.72 ENSDART00000155599
zgc:113176
zgc:113176
chr19_-_42045372 2.69 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr21_+_22840246 2.67 ENSDART00000151621
birc2
baculoviral IAP repeat containing 2
chr23_+_33991509 2.65 ENSDART00000145161
fam50a
family with sequence similarity 50, member A
chr10_+_26652859 2.64 ENSDART00000079174
htatsf1
HIV-1 Tat specific factor 1
chr8_+_28358161 2.63 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr15_-_18162647 2.61 ENSDART00000012064
pih1d2
PIH1 domain containing 2
chr5_-_55933420 2.61 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr3_-_30488063 2.59 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr22_-_18179214 2.58 ENSDART00000129576
si:ch211-125m10.6
si:ch211-125m10.6
chr15_-_47865063 2.58 ENSDART00000151600
h3f3b.1
H3 histone, family 3B.1
chr11_+_24800156 2.57 ENSDART00000131976
adipor1a
adiponectin receptor 1a
chr4_+_77047067 2.56 ENSDART00000174206
znf1009
zinc finger protein 1009

Network of associatons between targets according to the STRING database.

First level regulatory network of barx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 25.1 GO:0046952 ketone body catabolic process(GO:0046952)
3.4 10.2 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
2.4 11.9 GO:0000012 single strand break repair(GO:0000012)
2.1 8.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
2.0 6.0 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
2.0 9.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
2.0 5.9 GO:0002836 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.8 5.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
1.4 4.2 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
1.4 5.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.3 5.2 GO:0009098 leucine biosynthetic process(GO:0009098)
1.3 5.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
1.2 10.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
1.1 4.4 GO:0099563 modification of synaptic structure(GO:0099563)
1.1 5.3 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.9 2.8 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.9 5.6 GO:0006788 heme oxidation(GO:0006788)
0.9 4.3 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.8 6.7 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.8 5.7 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.8 7.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.8 5.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.7 6.5 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.7 7.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.7 2.8 GO:0051876 pigment granule dispersal(GO:0051876)
0.7 5.4 GO:0043584 nose development(GO:0043584)
0.7 2.7 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.7 2.0 GO:0035973 aggrephagy(GO:0035973)
0.6 2.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.6 7.0 GO:0046548 retinal rod cell development(GO:0046548)
0.6 11.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.6 3.9 GO:0032387 negative regulation of intracellular transport(GO:0032387) intraciliary transport involved in cilium morphogenesis(GO:0035735) negative regulation of intracellular protein transport(GO:0090317)
0.5 3.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.5 2.0 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.5 1.5 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.5 6.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.5 6.9 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.5 2.7 GO:0030242 pexophagy(GO:0030242)
0.5 11.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.4 1.3 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.4 8.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.4 1.3 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.4 1.6 GO:0001839 neural plate morphogenesis(GO:0001839)
0.4 2.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 4.1 GO:0060612 adipose tissue development(GO:0060612)
0.4 8.5 GO:0048844 artery morphogenesis(GO:0048844)
0.4 3.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.4 4.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.4 2.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.4 16.2 GO:0007586 digestion(GO:0007586)
0.3 2.0 GO:0021767 mammillary body development(GO:0021767)
0.3 1.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.3 4.0 GO:0001881 receptor recycling(GO:0001881)
0.3 1.0 GO:0006089 lactate metabolic process(GO:0006089)
0.3 12.3 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.3 1.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.3 2.6 GO:0090148 membrane fission(GO:0090148)
0.3 2.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 1.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 15.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.3 4.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.3 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.9 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 2.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 6.1 GO:0042073 intraciliary transport(GO:0042073)
0.2 2.0 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.2 2.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.2 2.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 1.4 GO:0070207 protein homotrimerization(GO:0070207)
0.2 3.1 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.2 1.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 7.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 2.0 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.2 5.2 GO:0001757 somite specification(GO:0001757)
0.2 5.6 GO:0006817 phosphate ion transport(GO:0006817)
0.2 3.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 2.4 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 1.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 5.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 9.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 2.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 1.1 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 6.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 5.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 16.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 4.8 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 1.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 2.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.0 GO:0045116 protein neddylation(GO:0045116)
0.1 2.6 GO:0060021 palate development(GO:0060021)
0.1 15.9 GO:0010506 regulation of autophagy(GO:0010506)
0.1 2.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 2.5 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 3.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 7.8 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.1 1.2 GO:0035675 neuromast hair cell development(GO:0035675)
0.1 2.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 1.8 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 10.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.1 4.7 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 2.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 4.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 2.8 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.5 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 9.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 2.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.9 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.4 GO:0006415 translational termination(GO:0006415)
0.1 1.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.2 GO:0016233 telomere capping(GO:0016233)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.9 GO:0051014 actin filament severing(GO:0051014)
0.1 5.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.8 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 3.6 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.1 0.4 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 5.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 6.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 2.8 GO:0007338 single fertilization(GO:0007338)
0.0 1.0 GO:0050821 protein stabilization(GO:0050821)
0.0 1.6 GO:0060037 pharyngeal system development(GO:0060037)
0.0 3.7 GO:0051051 negative regulation of transport(GO:0051051)
0.0 13.5 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.0 2.0 GO:0090174 vesicle fusion(GO:0006906) organelle membrane fusion(GO:0090174)
0.0 1.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 10.2 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 2.8 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 3.5 GO:0007051 spindle organization(GO:0007051)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 6.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.5 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 2.7 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108) negative regulation of mesoderm development(GO:2000381)
0.0 6.8 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 2.1 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 0.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 4.9 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.8 GO:0016197 endosomal transport(GO:0016197)
0.0 6.9 GO:0031175 neuron projection development(GO:0031175)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:1990072 TRAPPIII protein complex(GO:1990072)
1.1 5.6 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.9 15.7 GO:0043209 myelin sheath(GO:0043209)
0.7 6.7 GO:0045171 intercellular bridge(GO:0045171)
0.7 2.6 GO:0097255 R2TP complex(GO:0097255)
0.6 4.8 GO:0035060 brahma complex(GO:0035060)
0.6 4.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.6 11.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.5 3.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 6.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 3.4 GO:0071914 prominosome(GO:0071914)
0.4 1.2 GO:1990879 CST complex(GO:1990879)
0.4 3.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 2.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 3.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 41.0 GO:0043025 neuronal cell body(GO:0043025)
0.3 4.3 GO:0030008 TRAPP complex(GO:0030008)
0.3 3.4 GO:0005682 U5 snRNP(GO:0005682)
0.3 2.9 GO:0070449 elongin complex(GO:0070449)
0.3 6.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 7.6 GO:0035861 site of double-strand break(GO:0035861)
0.2 4.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 5.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 2.1 GO:0005686 U2 snRNP(GO:0005686)
0.2 1.4 GO:1990130 Iml1 complex(GO:1990130)
0.2 1.4 GO:0071818 BAT3 complex(GO:0071818)
0.2 7.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 11.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.4 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 2.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 26.4 GO:0030424 axon(GO:0030424)
0.1 8.3 GO:0030141 secretory granule(GO:0030141)
0.1 1.0 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 9.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.4 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 2.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 21.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 4.5 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 6.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 5.4 GO:0005871 kinesin complex(GO:0005871)
0.1 13.4 GO:0005635 nuclear envelope(GO:0005635)
0.1 3.4 GO:0005776 autophagosome(GO:0005776)
0.1 7.8 GO:0005769 early endosome(GO:0005769)
0.1 19.8 GO:0043005 neuron projection(GO:0043005)
0.1 3.0 GO:0001726 ruffle(GO:0001726)
0.1 1.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 14.1 GO:0005813 centrosome(GO:0005813)
0.1 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 4.7 GO:0098858 actin-based cell projection(GO:0098858)
0.1 4.6 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.6 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 3.1 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.2 GO:0031252 cell leading edge(GO:0031252)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.1 GO:0042383 sarcolemma(GO:0042383)
0.0 15.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 25.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
4.8 19.1 GO:0044548 S100 protein binding(GO:0044548)
2.8 8.5 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
2.6 7.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
2.0 6.0 GO:0070336 flap-structured DNA binding(GO:0070336)
1.9 5.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.3 5.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.3 5.2 GO:0030626 U12 snRNA binding(GO:0030626)
1.2 3.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
1.1 7.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.9 5.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 4.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.8 12.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.8 10.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.8 3.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.8 5.4 GO:0019809 spermidine binding(GO:0019809)
0.8 5.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.6 8.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.5 9.9 GO:0015026 coreceptor activity(GO:0015026)
0.5 2.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 2.5 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.5 6.1 GO:0045503 dynein light chain binding(GO:0045503)
0.5 10.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 3.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 2.5 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 4.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.4 16.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.4 0.8 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 1 melanocortin receptor binding(GO:0070996)
0.4 2.3 GO:0032052 bile acid binding(GO:0032052)
0.4 3.0 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.4 9.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.4 2.8 GO:0031419 cobalamin binding(GO:0031419)
0.4 4.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 4.6 GO:0031628 opioid receptor binding(GO:0031628)
0.3 2.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.3 6.0 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.3 1.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 1.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 8.3 GO:0003684 damaged DNA binding(GO:0003684)
0.2 2.7 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 9.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 6.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.4 GO:0036122 BMP binding(GO:0036122)
0.2 9.0 GO:0044325 ion channel binding(GO:0044325)
0.2 3.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 2.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.0 GO:0031386 protein tag(GO:0031386)
0.1 1.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 6.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 8.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 4.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 9.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 3.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 2.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 26.8 GO:0008017 microtubule binding(GO:0008017)
0.1 12.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.2 GO:0019003 GDP binding(GO:0019003)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.7 GO:0005537 mannose binding(GO:0005537)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.5 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 8.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 3.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 3.0 GO:0003682 chromatin binding(GO:0003682)
0.0 3.9 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 4.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 18.1 PID E2F PATHWAY E2F transcription factor network
0.2 4.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 1.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 2.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 5.6 PID BMP PATHWAY BMP receptor signaling
0.1 5.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 6.5 PID P73PATHWAY p73 transcription factor network
0.1 5.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 11.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 19.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 5.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 8.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.5 4.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.5 5.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.4 4.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 1.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 5.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 7.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 5.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 5.4 REACTOME KINESINS Genes involved in Kinesins
0.2 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 2.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 8.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 5.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 3.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 4.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 4.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex