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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for bbx

Z-value: 0.74

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Transcription factors associated with bbx

Gene Symbol Gene ID Gene Info
bbx
ENSDARG00000012699 BBX high mobility group box domain containing

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bbxdr11_v1_chr10_-_28525611_285256110.241.9e-02Click!

Activity profile of bbx motif

Sorted Z-values of bbx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_45235947 7.34 ENSDART00000164436
si:dkey-33i11.4
si:dkey-33i11.4
chr8_-_36370552 4.61 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
si:busm1-104n07.3
chr19_-_32940040 4.37 ENSDART00000179947
azin1b
antizyme inhibitor 1b
chr8_-_36327328 4.24 ENSDART00000183333
zgc:103700
zgc:103700
chr11_+_40812590 3.57 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr8_-_36469117 3.56 ENSDART00000111240
mhc2dab
major histocompatibility complex class II DAB gene
chr18_+_39060687 3.56 ENSDART00000098729
ENSDART00000136367
zgc:171509
zgc:171509
chr22_+_9939901 3.49 ENSDART00000169777
ENSDART00000081420
zgc:171686
zgc:171686
chr23_+_19670085 3.41 ENSDART00000031872
kctd6b
potassium channel tetramerization domain containing 6b
chr11_-_27501027 3.33 ENSDART00000065889
wnt7aa
wingless-type MMTV integration site family, member 7Aa
chr6_-_19042294 3.05 ENSDART00000159461
si:rp71-81e14.2
si:rp71-81e14.2
chr8_+_21114338 2.98 ENSDART00000002186
uck2a
uridine-cytidine kinase 2a
chr3_-_37759969 2.86 ENSDART00000151105
ENSDART00000151208
si:dkey-260c8.6
si:dkey-260c8.6
chr19_-_40198478 2.83 ENSDART00000191736
grn2
granulin 2
chr17_-_51893123 2.72 ENSDART00000103350
ENSDART00000017329
numb
numb homolog (Drosophila)
chr6_+_37301341 2.65 ENSDART00000104180
zranb2
zinc finger, RAN-binding domain containing 2
chr3_-_36612877 2.63 ENSDART00000167164
si:dkeyp-72e1.7
si:dkeyp-72e1.7
chr3_+_12755535 2.63 ENSDART00000161286
cyp2k17
cytochrome P450, family 2, subfamily K, polypeptide17
chr21_+_21263988 2.58 ENSDART00000089651
ENSDART00000108978
ccdc61
coiled-coil domain containing 61
chr10_+_23511816 2.40 ENSDART00000127255
zmp:0000000924
zmp:0000000924
chr21_+_38732945 2.38 ENSDART00000076157
rab24
RAB24, member RAS oncogene family
chr1_+_45121393 2.31 ENSDART00000142702
muc13a
mucin 13a, cell surface associated
chr16_-_47427016 2.23 ENSDART00000074575
sept7b
septin 7b
chr13_-_7233811 2.23 ENSDART00000162026
ninl
ninein-like
chr6_+_36839509 2.16 ENSDART00000190605
ENSDART00000104160
zgc:110788
zgc:110788
chr16_+_32014552 2.12 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr19_+_33093395 2.11 ENSDART00000019459
fam91a1
family with sequence similarity 91, member A1
chr16_-_40373836 2.01 ENSDART00000134498
si:dkey-242e21.3
si:dkey-242e21.3
chr5_+_36650096 2.01 ENSDART00000111414
alkbh6
alkB homolog 6
chr1_-_7673376 2.00 ENSDART00000013264
arglu1b
arginine and glutamate rich 1b
chr17_+_24718272 1.98 ENSDART00000007271
mtfr1l
mitochondrial fission regulator 1-like
chr6_+_6780873 1.97 ENSDART00000011865
sec23b
Sec23 homolog B, COPII coat complex component
chr11_-_18323059 1.93 ENSDART00000182590
SFMBT1
Scm like with four mbt domains 1
chr5_+_37744625 1.92 ENSDART00000014031
dpf2
D4, zinc and double PHD fingers family 2
chr8_+_21229718 1.84 ENSDART00000100222
cry1ba
cryptochrome circadian clock 1ba
chr1_+_2431956 1.83 ENSDART00000183832
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr8_-_14091886 1.76 ENSDART00000137857
si:ch211-229n2.7
si:ch211-229n2.7
chr8_+_20438884 1.76 ENSDART00000016422
ENSDART00000133794
mknk2b
MAP kinase interacting serine/threonine kinase 2b
chr10_-_42751641 1.76 ENSDART00000182734
ENSDART00000113926
zgc:100918
zgc:100918
chr16_+_25535993 1.70 ENSDART00000077436
mylipb
myosin regulatory light chain interacting protein b
chr10_-_26218354 1.68 ENSDART00000180764
arfip2b
ADP-ribosylation factor interacting protein 2b
chr2_-_32237916 1.64 ENSDART00000141418
fam49ba
family with sequence similarity 49, member Ba
chr16_+_23403602 1.63 ENSDART00000159848
s100w
S100 calcium binding protein W
chr25_+_16646113 1.56 ENSDART00000110426
cecr2
cat eye syndrome chromosome region, candidate 2
chr24_-_9002038 1.46 ENSDART00000066783
ENSDART00000150185
mppe1
metallophosphoesterase 1
chr8_+_20951590 1.45 ENSDART00000138728
si:dkeyp-82a1.1
si:dkeyp-82a1.1
chr1_-_28831848 1.44 ENSDART00000148536
GK3P
zgc:172295
chr7_-_54320088 1.42 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr12_-_33770299 1.41 ENSDART00000189849
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr12_-_3453589 1.37 ENSDART00000175918
CABZ01063170.1

chr6_+_30430591 1.36 ENSDART00000108943
shroom2a
shroom family member 2a
chr17_-_14523722 1.34 ENSDART00000024726
daam1a
dishevelled associated activator of morphogenesis 1a
chr16_-_41465542 1.33 ENSDART00000169116
ENSDART00000187446
cpne4a
copine IVa
chr5_+_69733096 1.33 ENSDART00000169013
arl6ip4
ADP-ribosylation factor-like 6 interacting protein 4
chr7_-_50395395 1.31 ENSDART00000065868
vps33b
vacuolar protein sorting 33B
chr7_-_50395059 1.30 ENSDART00000191150
vps33b
vacuolar protein sorting 33B
chr10_-_43771447 1.29 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr3_+_32789605 1.27 ENSDART00000171895
tbc1d10b
TBC1 domain family, member 10b
chr12_-_17686404 1.18 ENSDART00000079065
ccz1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr19_+_33093577 1.14 ENSDART00000180317
fam91a1
family with sequence similarity 91, member A1
chr4_+_75577480 1.12 ENSDART00000188196
si:ch211-227e10.1
si:ch211-227e10.1
chr20_-_25626428 1.12 ENSDART00000136475
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr7_+_72003301 1.12 ENSDART00000012918
ENSDART00000182268
ENSDART00000185750
psmd9
proteasome 26S subunit, non-ATPase 9
chr3_-_34816893 1.11 ENSDART00000084448
ENSDART00000154696
psmd11a
proteasome 26S subunit, non-ATPase 11a
chr13_-_50565338 1.11 ENSDART00000062684
blnk
B cell linker
chr13_-_24669258 1.11 ENSDART00000000831
znf511
zinc finger protein 511
chr25_+_22107643 1.10 ENSDART00000089680
sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr20_-_25626693 1.10 ENSDART00000132247
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr20_-_39735952 1.09 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tpd52l1
tumor protein D52-like 1
chr5_-_30978381 1.08 ENSDART00000127787
spns3
spinster homolog 3 (Drosophila)
chr2_-_22659450 1.03 ENSDART00000115025
thap4
THAP domain containing 4
chr20_-_20248408 1.00 ENSDART00000183234
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr7_+_10701770 0.98 ENSDART00000167323
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr15_-_20190052 0.97 ENSDART00000157149
exoc3l2b
exocyst complex component 3-like 2b
chr15_-_15983183 0.96 ENSDART00000154841
synrg
synergin, gamma
chr13_-_23095006 0.95 ENSDART00000089242
kif1bp
kif1 binding protein
chr22_+_35930526 0.94 ENSDART00000169242
LO016987.1

chr4_+_12031958 0.92 ENSDART00000044154
tnnt2c
troponin T2c, cardiac
chr17_+_21546993 0.92 ENSDART00000182387
chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr18_+_6857071 0.92 ENSDART00000018735
ENSDART00000181969
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr4_+_70342815 0.91 ENSDART00000126434
si:ch211-76m11.3
si:ch211-76m11.3
chr19_-_3773905 0.90 ENSDART00000168433
btr20
bloodthirsty-related gene family, member 20
chr18_+_17493859 0.89 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr13_+_18507592 0.86 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr3_+_4113551 0.86 ENSDART00000192309
LO018551.1

chr12_+_27156943 0.85 ENSDART00000153030
ENSDART00000001737
skap1
src kinase associated phosphoprotein 1
chr1_+_35956435 0.82 ENSDART00000085021
ENSDART00000148505
mmaa
methylmalonic aciduria (cobalamin deficiency) cblA type
chr15_-_1022436 0.82 ENSDART00000156003
znf1010
zinc finger protein 1010
chr1_+_55535827 0.81 ENSDART00000152784
adgre16
adhesion G protein-coupled receptor E16
chr23_+_17512037 0.80 ENSDART00000054738
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr14_+_36628131 0.80 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr3_+_54761569 0.80 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
si:ch211-74m13.1
chr20_-_25626198 0.77 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr16_+_12740790 0.77 ENSDART00000132957
epn1
epsin 1
chr15_+_16886196 0.75 ENSDART00000139296
ENSDART00000049196
gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr5_-_42883761 0.75 ENSDART00000167374
BX323596.2

chr4_-_14531687 0.74 ENSDART00000182093
ENSDART00000159447
plxnb2a
plexin b2a
chr1_+_55563532 0.74 ENSDART00000152549
adgre15
adhesion G protein-coupled receptor E15
chr4_-_67969695 0.70 ENSDART00000190016
si:ch211-223k15.1
si:ch211-223k15.1
chr11_-_23322182 0.69 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr9_+_19623363 0.65 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pdxka
pyridoxal (pyridoxine, vitamin B6) kinase a
chr1_+_23784905 0.64 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr15_-_15983428 0.64 ENSDART00000115129
synrg
synergin, gamma
chr3_+_32553714 0.63 ENSDART00000165638
pax10
paired box 10
chr13_+_23095228 0.62 ENSDART00000189068
ENSDART00000188624
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr4_-_33071267 0.61 ENSDART00000186314
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr1_+_12767318 0.61 ENSDART00000162652
pcdh10a
protocadherin 10a
chr16_-_13622794 0.60 ENSDART00000146953
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr4_+_47636303 0.60 ENSDART00000167272
ENSDART00000166961
BX324142.1

chr1_-_45039726 0.59 ENSDART00000186188
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr6_-_35052388 0.59 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr1_+_52481332 0.58 ENSDART00000074231
cldnd1b
claudin domain containing 1b
chr25_-_16076257 0.57 ENSDART00000140780
ovch2
ovochymase 2
chr14_+_36246726 0.54 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr4_+_35189063 0.53 ENSDART00000185091
si:dkey-269p2.1
si:dkey-269p2.1
chr12_+_4222854 0.52 ENSDART00000144881
mapk7
mitogen-activated protein kinase 7
chr23_+_2703044 0.52 ENSDART00000182512
ENSDART00000105286
ncoa6
nuclear receptor coactivator 6
chr7_+_36898850 0.51 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr23_+_40139765 0.50 ENSDART00000185376
gpsm2l
G protein signaling modulator 2, like
chr4_+_54645654 0.50 ENSDART00000192864
si:ch211-227e10.1
si:ch211-227e10.1
chr7_+_11459235 0.49 ENSDART00000159611
il16
interleukin 16
chr18_-_26510545 0.49 ENSDART00000135133
FRMD5
si:ch211-69m14.1
chr15_+_23528310 0.46 ENSDART00000152523
si:dkey-182i3.8
si:dkey-182i3.8
chr17_+_44697604 0.42 ENSDART00000156625
pgfb
placental growth factor b
chr4_+_76442674 0.41 ENSDART00000164825
si:dkey-16p6.1
si:dkey-16p6.1
chr17_+_8799451 0.41 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr24_-_36727922 0.40 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr25_-_12730260 0.39 ENSDART00000171834
klhdc4
kelch domain containing 4
chr9_-_15424639 0.39 ENSDART00000124346
fn1a
fibronectin 1a
chr1_+_19433004 0.37 ENSDART00000133959
clockb
clock circadian regulator b
chr16_-_20492799 0.36 ENSDART00000014769
chn2
chimerin 2
chr1_+_55643198 0.34 ENSDART00000060693
adgre7
adhesion G protein-coupled receptor E7
chr7_+_50395856 0.34 ENSDART00000032324
hddc3
HD domain containing 3
chr5_-_55933420 0.32 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr19_-_438337 0.31 ENSDART00000127985
MTERF1
mitochondrial transcription termination factor 1
chr4_-_42397126 0.31 ENSDART00000162437
si:ch211-129p6.2
si:ch211-129p6.2
chr24_+_41989108 0.30 ENSDART00000169725
zbtb14
zinc finger and BTB domain containing 14
chr4_-_36033377 0.30 ENSDART00000164348
ENSDART00000187058
zgc:174180
zgc:174180
chr18_-_6856380 0.27 ENSDART00000175747
ppp6r2b
protein phosphatase 6, regulatory subunit 2b
chr12_-_9700605 0.23 ENSDART00000161063
heatr1
HEAT repeat containing 1
chr11_+_2416064 0.21 ENSDART00000067117
ube2v1
ubiquitin-conjugating enzyme E2 variant 1
chr4_-_36032930 0.21 ENSDART00000191414
zgc:174180
zgc:174180
chr4_-_73548389 0.21 ENSDART00000174327
ENSDART00000150753
ENSDART00000170775
si:ch73-266f23.1
si:ch73-266f23.1
chr13_-_9608943 0.20 ENSDART00000058066
cpxm1a
carboxypeptidase X (M14 family), member 1a
chr15_-_35212462 0.19 ENSDART00000043960
agfg1a
ArfGAP with FG repeats 1a
chr4_+_57194439 0.19 ENSDART00000075265
si:dkey-16p6.4
si:dkey-16p6.4
chr10_-_29892486 0.17 ENSDART00000099983
bsx
brain-specific homeobox
chr21_-_22678195 0.17 ENSDART00000171231
gig2g
grass carp reovirus (GCRV)-induced gene 2g
chr4_-_76102637 0.16 ENSDART00000186496
zgc:110171
zgc:110171
chr3_+_13862753 0.14 ENSDART00000168315
ilf3b
interleukin enhancer binding factor 3b
chr15_-_19051152 0.14 ENSDART00000186453
arhgap32a
Rho GTPase activating protein 32a
chr8_-_40205712 0.14 ENSDART00000158927
anapc5
anaphase promoting complex subunit 5
chr20_+_25626479 0.14 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr14_-_4177311 0.13 ENSDART00000128129
si:dkey-185e18.7
si:dkey-185e18.7
chr1_+_55583116 0.10 ENSDART00000152163
adgre19
adhesion G protein-coupled receptor E19
chr12_+_20700961 0.10 ENSDART00000016099
si:ch211-119c20.2
si:ch211-119c20.2
chr21_-_22648007 0.09 ENSDART00000121788
gig2l
grass carp reovirus (GCRV)-induced gene 2l
chr7_+_24729558 0.05 ENSDART00000111542
ENSDART00000170100
shroom4
shroom family member 4
chr19_+_43341424 0.04 ENSDART00000134815
sesn2
sestrin 2
chr1_+_29858032 0.04 ENSDART00000054066
zic2b
zic family member 2 (odd-paired homolog, Drosophila) b
chr14_+_36223097 0.03 ENSDART00000186872
pitx2
paired-like homeodomain 2
chr17_+_22381215 0.01 ENSDART00000162670
ENSDART00000128875
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr4_+_11135048 0.01 ENSDART00000142389
cracr2ab
calcium release activated channel regulator 2Ab
chr23_-_18381361 0.00 ENSDART00000016891
hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10

Network of associatons between targets according to the STRING database.

First level regulatory network of bbx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 0.8 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.7 4.4 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.5 2.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.5 3.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.4 2.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 3.0 GO:0044211 CTP salvage(GO:0044211)
0.4 1.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 1.8 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.3 3.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 1.4 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 7.8 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 1.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 0.7 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 0.6 GO:0007414 axonal defasciculation(GO:0007414)
0.1 2.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.4 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.1 1.0 GO:0051601 exocyst localization(GO:0051601)
0.1 2.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 2.6 GO:0098534 centriole assembly(GO:0098534)
0.1 2.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 1.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 3.3 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.1 1.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 2.3 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.1 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.8 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.6 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 3.1 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.0 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.4 GO:0021986 habenula development(GO:0021986)
0.0 0.3 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0021982 pineal gland development(GO:0021982)
0.0 0.9 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 4.9 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.7 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.8 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.9 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.9 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 2.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.5 2.6 GO:0033263 CORVET complex(GO:0033263)
0.2 2.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0031010 ISWI-type complex(GO:0031010)
0.1 3.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.9 GO:0071565 nBAF complex(GO:0071565)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 2.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0030882 lipid antigen binding(GO:0030882)
0.7 3.0 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.7 4.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.6 1.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 3.0 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 1.4 GO:0002020 protease binding(GO:0002020)
0.1 2.1 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 3.3 GO:0005109 frizzled binding(GO:0005109)
0.1 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 1.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 7.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.0 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.7 GO:0019904 protein domain specific binding(GO:0019904)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 3.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane