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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for bcl11aa

Z-value: 0.99

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Transcription factors associated with bcl11aa

Gene Symbol Gene ID Gene Info
bcl11aa
ENSDARG00000061352 BAF chromatin remodeling complex subunit BCL11A a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl11aadr11_v1_chr13_+_25846528_258465280.642.9e-12Click!

Activity profile of bcl11aa motif

Sorted Z-values of bcl11aa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_11724230 9.24 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr7_-_7810348 8.20 ENSDART00000171984
cxcl19
chemokine (C-X-C motif) ligand 19
chr14_+_38786298 7.34 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr18_+_35742838 6.62 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr2_+_32796873 5.94 ENSDART00000077511
ccr9a
chemokine (C-C motif) receptor 9a
chr11_+_25139495 5.63 ENSDART00000168368
si:ch211-25d12.7
si:ch211-25d12.7
chr2_-_6482240 5.49 ENSDART00000132623
rgs13
regulator of G protein signaling 13
chr2_+_21855036 5.42 ENSDART00000140012
ca8
carbonic anhydrase VIII
chr19_+_30633453 4.77 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr20_+_38285671 4.74 ENSDART00000061432
ccl38a.4
chemokine (C-C motif) ligand 38, duplicate 4
chr8_+_36803415 4.70 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr7_-_34265481 4.57 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr11_+_4026229 4.55 ENSDART00000041417
camk1b
calcium/calmodulin-dependent protein kinase Ib
chr11_+_30057762 4.52 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr22_-_31517300 4.33 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr5_-_31926906 4.16 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr19_+_40350468 4.15 ENSDART00000087444
hepacam2
HEPACAM family member 2
chr4_-_4261673 4.15 ENSDART00000150694
cd9b
CD9 molecule b
chr7_+_39706004 4.13 ENSDART00000161856
ccl36.1
chemokine (C-C motif) ligand 36, duplicate 1
chr2_+_21855291 4.06 ENSDART00000186204
ca8
carbonic anhydrase VIII
chr19_-_34011340 3.91 ENSDART00000172618
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr2_-_31302615 3.86 ENSDART00000034784
ENSDART00000060812
adcyap1b
adenylate cyclase activating polypeptide 1b
chr3_+_28576173 3.84 ENSDART00000151189
sept12
septin 12
chr2_+_36898982 3.74 ENSDART00000084859
rabgap1l2
RAB GTPase activating protein 1-like 2
chr20_-_20821783 3.72 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
ckbb
creatine kinase, brain b
chr20_-_14054083 3.70 ENSDART00000009549
rhag
Rh associated glycoprotein
chr7_-_29571615 3.62 ENSDART00000019140
rorab
RAR-related orphan receptor A, paralog b
chr3_-_45298487 3.60 ENSDART00000102245
pdpk1a
3-phosphoinositide dependent protein kinase 1a
chr6_-_40651944 3.48 ENSDART00000187423
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr19_-_11425542 3.41 ENSDART00000177875
ENSDART00000080762
sept7a
septin 7a
chr16_-_22863603 3.35 ENSDART00000098400
ENSDART00000183963
shc1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_+_38280454 3.31 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr6_-_18960105 3.30 ENSDART00000185278
ENSDART00000162968
sept9b
septin 9b
chr6_+_30668098 3.28 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr14_-_33095917 3.17 ENSDART00000074720
dlg3
discs, large homolog 3 (Drosophila)
chr16_-_22863348 3.15 ENSDART00000147609
shc1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_-_13502549 2.97 ENSDART00000140366
si:ch211-266a5.12
si:ch211-266a5.12
chr4_-_23858900 2.91 ENSDART00000123199
usp6nl
USP6 N-terminal like
chr24_+_11334733 2.85 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr11_+_24703108 2.83 ENSDART00000159173
gpr25
G protein-coupled receptor 25
chr25_-_14637660 2.83 ENSDART00000143666
nav2b
neuron navigator 2b
chr1_+_39597809 2.74 ENSDART00000122700
tenm3
teneurin transmembrane protein 3
chr15_+_25489406 2.62 ENSDART00000162482
zgc:152863
zgc:152863
chr16_+_8716800 2.61 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr3_-_19367081 2.60 ENSDART00000191369
s1pr5a
sphingosine-1-phosphate receptor 5a
chr22_+_21255860 2.53 ENSDART00000134893
cpamd8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr1_+_23398405 2.51 ENSDART00000102646
rhoh
ras homolog family member H
chr10_-_15128771 2.49 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr22_-_15578402 2.47 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr10_+_29204581 2.47 ENSDART00000148503
picalma
phosphatidylinositol binding clathrin assembly protein a
chr8_+_47188154 2.46 ENSDART00000137319
si:dkeyp-100a1.6
si:dkeyp-100a1.6
chr5_+_24156170 2.45 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr9_-_25425381 2.45 ENSDART00000129522
acvr2aa
activin A receptor type 2Aa
chr5_-_38384289 2.36 ENSDART00000135260
mink1
misshapen-like kinase 1
chr16_+_26439518 2.32 ENSDART00000041787
trim35-28
tripartite motif containing 35-28
chr7_-_26263183 2.31 ENSDART00000079357
ENSDART00000190369
ENSDART00000193154
ENSDART00000101109
ap1s1
adaptor-related protein complex 1, sigma 1 subunit
chr25_+_31929325 2.29 ENSDART00000181095
apba2a
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr16_+_50741154 2.28 ENSDART00000101627
IGLON5
zgc:110372
chr19_+_29798064 2.27 ENSDART00000167803
ENSDART00000051804
marcksl1b
MARCKS-like 1b
chr7_-_30553588 2.24 ENSDART00000139546
sltm
SAFB-like, transcription modulator
chr22_-_20309283 2.24 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
si:dkey-110c1.10
chr18_+_19131773 2.23 ENSDART00000060766
rab11a
RAB11a, member RAS oncogene family
chr19_+_3849378 2.21 ENSDART00000166218
ENSDART00000159228
oscp1a
organic solute carrier partner 1a
chr7_-_7984015 2.19 ENSDART00000163203
si:cabz01030277.1
si:cabz01030277.1
chr18_+_40525408 2.17 ENSDART00000132833
vwa7
von Willebrand factor A domain containing 7
chr25_-_22889519 2.16 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr24_-_21921262 2.15 ENSDART00000186061
ENSDART00000187846
tagln3b
transgelin 3b
chr24_-_18876877 2.13 ENSDART00000186269
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr23_+_30898013 2.09 ENSDART00000146859
cables2a
Cdk5 and Abl enzyme substrate 2a
chr17_+_26569601 2.09 ENSDART00000153897
ndnfl
neuron-derived neurotrophic factor , like
chr24_-_18877118 2.08 ENSDART00000092783
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr7_-_26262978 2.07 ENSDART00000137769
ap1s1
adaptor-related protein complex 1, sigma 1 subunit
chr8_-_43456025 2.07 ENSDART00000001092
ENSDART00000140618
ncor2
nuclear receptor corepressor 2
chr24_+_37722048 2.06 ENSDART00000191918
rab11fip3
RAB11 family interacting protein 3 (class II)
chr3_-_56924654 1.92 ENSDART00000157038
hid1a
HID1 domain containing a
chr22_-_10397600 1.88 ENSDART00000181964
ENSDART00000142886
nisch
nischarin
chr3_-_21382491 1.86 ENSDART00000016562
itga2b
integrin, alpha 2b
chr2_+_22694382 1.86 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr3_+_25191467 1.85 ENSDART00000156956
ENSDART00000154799
il2rb
interleukin 2 receptor, beta
chr7_-_2163361 1.84 ENSDART00000173654
si:cabz01007812.1
si:cabz01007812.1
chr19_+_19786117 1.84 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr17_+_1627379 1.79 ENSDART00000184050
LO018432.1

chr9_-_31108285 1.77 ENSDART00000003193
gpr183a
G protein-coupled receptor 183a
chr19_-_7144548 1.74 ENSDART00000147177
ENSDART00000134850
psmb8a
psmb13a
proteasome subunit beta 8A
proteasome subunit beta 13a
chr18_+_40354998 1.73 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr8_+_10835456 1.72 ENSDART00000151388
mapk13
mitogen-activated protein kinase 13
chr16_-_17300030 1.70 ENSDART00000149267
kel
Kell blood group, metallo-endopeptidase
chr11_-_40647190 1.69 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr18_+_27571448 1.68 ENSDART00000147886
cd82b
CD82 molecule b
chr17_+_15433518 1.67 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr23_-_36316352 1.66 ENSDART00000014840
nfe2
nuclear factor, erythroid 2
chr2_-_36925561 1.66 ENSDART00000187690
map1sb
microtubule-associated protein 1Sb
chr3_-_25369557 1.64 ENSDART00000055491
smurf2
SMAD specific E3 ubiquitin protein ligase 2
chr6_+_6780873 1.63 ENSDART00000011865
sec23b
Sec23 homolog B, COPII coat complex component
chr25_-_27564205 1.57 ENSDART00000157319
hyal4
hyaluronoglucosaminidase 4
chr10_-_43771447 1.56 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr7_+_46368520 1.55 ENSDART00000192821
znf536
zinc finger protein 536
chr1_-_41982582 1.53 ENSDART00000014678
adra1d
adrenoceptor alpha 1D
chr17_+_15433671 1.48 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr6_-_16394528 1.47 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr9_+_17984358 1.44 ENSDART00000192399
akap11
A kinase (PRKA) anchor protein 11
chr17_-_44776224 1.43 ENSDART00000156195
zdhhc22
zinc finger, DHHC-type containing 22
chr24_-_7826489 1.42 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr9_-_31524907 1.41 ENSDART00000142904
ENSDART00000127214
ENSDART00000133427
ENSDART00000146268
ENSDART00000182541
ENSDART00000184736
tmtc4
transmembrane and tetratricopeptide repeat containing 4
chr14_-_33177935 1.39 ENSDART00000180583
ENSDART00000078856
dlg3
discs, large homolog 3 (Drosophila)
chr24_-_31306724 1.37 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr11_+_8129536 1.37 ENSDART00000158112
ENSDART00000011183
prkacba
protein kinase, cAMP-dependent, catalytic, beta a
chr2_+_36046126 1.34 ENSDART00000085976
ENSDART00000171680
smg7
SMG7 nonsense mediated mRNA decay factor
chr6_-_19023468 1.33 ENSDART00000184729
sept9b
septin 9b
chr25_-_35996141 1.30 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr2_+_12255568 1.29 ENSDART00000184164
ENSDART00000013454
prtfdc1
phosphoribosyl transferase domain containing 1
chr10_-_23358357 1.29 ENSDART00000135475
cadm2a
cell adhesion molecule 2a
chr15_+_39977461 1.28 ENSDART00000063786
cab39
calcium binding protein 39
chr4_+_17336557 1.27 ENSDART00000111650
pmch
pro-melanin-concentrating hormone
chr21_+_5915041 1.27 ENSDART00000151370
prodha
proline dehydrogenase (oxidase) 1a
chr10_-_28395620 1.24 ENSDART00000168907
CR392341.4

chr20_+_46216431 1.23 ENSDART00000185384
stx7l
syntaxin 7-like
chr1_+_33217911 1.19 ENSDART00000136761
prkx
protein kinase, X-linked
chr25_+_14017609 1.18 ENSDART00000129105
ENSDART00000125733
chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr12_+_18543783 1.17 ENSDART00000148326
ENSDART00000134530
mlst8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr6_+_13606410 1.13 ENSDART00000104716
asic4b
acid-sensing (proton-gated) ion channel family member 4b
chr2_-_21786826 1.10 ENSDART00000016208
chd7
chromodomain helicase DNA binding protein 7
chr13_-_6081803 1.10 ENSDART00000099224
dld
deltaD
chr2_-_14387335 1.09 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr3_+_54761569 1.08 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
si:ch211-74m13.1
chr8_+_25342896 1.05 ENSDART00000129032
CR847543.1

chr25_+_18954189 1.05 ENSDART00000123207
tdg.2
thymine DNA glycosylase, tandem duplicate 2
chr19_-_30810328 1.05 ENSDART00000184875
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr7_+_59677273 1.04 ENSDART00000039535
ENSDART00000132044
trmt44
tRNA methyltransferase 44 homolog
chr3_+_30968176 1.03 ENSDART00000186266
prf1.9
perforin 1.9
chr16_+_26439939 1.02 ENSDART00000143073
trim35-28
tripartite motif containing 35-28
chr17_-_10043273 1.01 ENSDART00000156078
baz1a
bromodomain adjacent to zinc finger domain, 1A
chr1_+_47335038 1.00 ENSDART00000188153
bcl9
B cell CLL/lymphoma 9
chr22_-_17729778 0.98 ENSDART00000192132
si:ch73-63e15.2
si:ch73-63e15.2
chr11_+_7580079 0.97 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adgrl2a
adhesion G protein-coupled receptor L2a
chr5_+_54422941 0.96 ENSDART00000175157
traf2b
Tnf receptor-associated factor 2b
chr5_-_38122126 0.95 ENSDART00000141791
ENSDART00000170528
si:ch211-284e13.6
si:ch211-284e13.6
chr15_-_34567370 0.95 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr17_-_45254585 0.92 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr9_+_38457806 0.90 ENSDART00000142512
mcm3ap
minichromosome maintenance complex component 3 associated protein
chr17_-_26868169 0.83 ENSDART00000157204
si:dkey-221l4.10
si:dkey-221l4.10
chr9_-_14504834 0.82 ENSDART00000056103
nrp2b
neuropilin 2b
chr25_+_18953756 0.81 ENSDART00000154291
tdg.2
thymine DNA glycosylase, tandem duplicate 2
chr9_+_38458193 0.74 ENSDART00000008053
mcm3ap
minichromosome maintenance complex component 3 associated protein
chr14_-_30967284 0.73 ENSDART00000149435
il2rgb
interleukin 2 receptor, gamma b
chr9_-_44939104 0.73 ENSDART00000192903
vil1
villin 1
chr25_+_15997957 0.69 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr9_+_51655636 0.65 ENSDART00000169908
RBMS1 (1 of many)
RNA binding motif single stranded interacting protein 1
chr1_-_16394814 0.62 ENSDART00000013024
fgf20a
fibroblast growth factor 20a
chr4_+_34126849 0.62 ENSDART00000162442
si:ch211-223g7.6
si:ch211-223g7.6
chr11_+_30058139 0.60 ENSDART00000112254
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr5_+_50953240 0.59 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr16_+_28547157 0.57 ENSDART00000109450
ENSDART00000165687
fam171a1
family with sequence similarity 171, member A1
chr11_-_12801157 0.56 ENSDART00000103449
txlng
taxilin gamma
chr4_+_20255160 0.55 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr11_-_12800945 0.54 ENSDART00000191178
txlng
taxilin gamma
chr9_+_33267211 0.53 ENSDART00000025635
usp9
ubiquitin specific peptidase 9
chr23_+_35847538 0.52 ENSDART00000143935
rarga
retinoic acid receptor gamma a
chr8_-_47844456 0.52 ENSDART00000145429
si:dkeyp-104h9.5
si:dkeyp-104h9.5
chr23_+_21978584 0.51 ENSDART00000145172
eif4g3b
eukaryotic translation initiation factor 4 gamma, 3b
chr24_+_31361407 0.51 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr15_-_26636826 0.50 ENSDART00000087632
slc47a4
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr16_+_46410520 0.49 ENSDART00000131072
rpz2
rapunzel 2
chr4_-_13518381 0.48 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr14_+_45970033 0.46 ENSDART00000047716
fermt3b
fermitin family member 3b
chr6_-_7438584 0.45 ENSDART00000053776
fkbp11
FK506 binding protein 11
chr4_+_12031958 0.43 ENSDART00000044154
tnnt2c
troponin T2c, cardiac
chr5_-_18446483 0.42 ENSDART00000180027
si:dkey-215k6.1
si:dkey-215k6.1
chr10_+_19039507 0.37 ENSDART00000193538
ENSDART00000111952
ENSDART00000180093
igsf9a
immunoglobulin superfamily, member 9a
chr24_+_19518570 0.36 ENSDART00000056081
sulf1
sulfatase 1
chr4_+_23117557 0.36 ENSDART00000066909
slc35e3
solute carrier family 35, member E3
chr16_+_8695595 0.34 ENSDART00000173249
si:cabz01093077.1
si:cabz01093077.1
chr3_+_30968883 0.34 ENSDART00000085736
prf1.9
perforin 1.9
chr19_+_7552699 0.34 ENSDART00000180788
ENSDART00000115058
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr8_-_25690966 0.33 ENSDART00000033701
sema3ga
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr4_+_16710001 0.32 ENSDART00000035899
pkp2
plakophilin 2
chr17_-_39761086 0.31 ENSDART00000032410
gpr132a
G protein-coupled receptor 132a
chr6_-_21830405 0.29 ENSDART00000151803
ENSDART00000113497
setd5
SET domain containing 5
chr3_-_56512473 0.28 ENSDART00000125439
ENSDART00000181743
cyth1a
cytohesin 1a
chr21_-_21096437 0.27 ENSDART00000186552
ank1b
ankyrin 1, erythrocytic b
chr17_+_23770848 0.25 ENSDART00000079646
kcnk18
potassium channel, subfamily K, member 18
chr23_+_21978816 0.25 ENSDART00000087110
eif4g3b
eukaryotic translation initiation factor 4 gamma, 3b
chr17_+_27134806 0.24 ENSDART00000151901
rps6ka1
ribosomal protein S6 kinase a, polypeptide 1
chr7_+_50109239 0.23 ENSDART00000021605
LRRC4C (1 of many)
si:dkey-6l15.1
chr15_+_37412883 0.23 ENSDART00000156474
zbtb32
zinc finger and BTB domain containing 32
chr3_+_15773991 0.22 ENSDART00000089923
znf652
zinc finger protein 652
chr10_+_41199660 0.21 ENSDART00000125314
adrb3b
adrenoceptor beta 3b
chr8_+_25173317 0.15 ENSDART00000142006
gpr61
G protein-coupled receptor 61
chr14_+_22022441 0.12 ENSDART00000149121
clcf1
cardiotrophin-like cytokine factor 1
chr20_+_34543365 0.09 ENSDART00000152073
si:ch211-242b18.1
si:ch211-242b18.1
chr13_+_31108334 0.09 ENSDART00000142245
arhgap22
Rho GTPase activating protein 22
chr16_-_13612650 0.08 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr16_+_27957808 0.06 ENSDART00000133696
znf804b
zinc finger protein 804B
chr5_-_41933912 0.04 ENSDART00000097574
ncor1
nuclear receptor corepressor 1
chr3_+_22905341 0.03 ENSDART00000111435
hdac5
histone deacetylase 5
chr14_+_24845941 0.03 ENSDART00000187513
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr24_-_36680261 0.02 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr21_+_11923701 0.00 ENSDART00000109292
ubap2a
ubiquitin associated protein 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl11aa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0015840 urea transport(GO:0015840)
0.8 2.5 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.7 2.7 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.6 5.9 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.6 1.8 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.3 3.7 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 15.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.3 1.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 1.5 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 2.8 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.2 9.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 9.5 GO:0036269 swimming behavior(GO:0036269)
0.2 0.7 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.2 2.2 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.2 1.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.2 1.9 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 0.5 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.6 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 1.4 GO:0045453 bone resorption(GO:0045453)
0.1 4.3 GO:0072348 sulfur compound transport(GO:0072348)
0.1 10.5 GO:0001945 lymph vessel development(GO:0001945)
0.1 3.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.0 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 3.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 4.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 11.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 2.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.1 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.8 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 1.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 5.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 1.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 4.1 GO:0007338 single fertilization(GO:0007338)
0.1 1.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.8 GO:0031641 regulation of myelination(GO:0031641)
0.1 10.1 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.2 GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.1 2.5 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 2.1 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.4 GO:0019835 cytolysis(GO:0019835)
0.0 4.2 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.4 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 1.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.6 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 4.8 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 2.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 2.5 GO:0060348 bone development(GO:0060348)
0.0 5.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 2.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 3.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.9 GO:0007596 blood coagulation(GO:0007596)
0.0 3.0 GO:0040008 regulation of growth(GO:0040008)
0.0 2.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.0 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 2.3 GO:0003407 neural retina development(GO:0003407)
0.0 1.2 GO:0048278 vesicle docking(GO:0048278)
0.0 1.6 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 4.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 2.2 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 1.2 GO:0031929 TOR signaling(GO:0031929)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 2.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 1.9 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 1.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 2.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.3 1.6 GO:0070390 transcription export complex 2(GO:0070390)
0.3 11.9 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.3 0.8 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.2 2.5 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 2.5 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0032433 filopodium tip(GO:0032433)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 5.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.9 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.7 GO:0005839 proteasome core complex(GO:0005839)
0.1 4.4 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 4.6 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 5.9 GO:0005769 early endosome(GO:0005769)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 3.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.0 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 1.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.7 8.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.6 2.8 GO:0060182 apelin receptor activity(GO:0060182)
0.3 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 9.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.8 GO:0008142 oxysterol binding(GO:0008142)
0.3 3.7 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 2.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 2.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 0.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 8.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 3.2 GO:0005504 fatty acid binding(GO:0005504)
0.2 1.9 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.2 6.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 1.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 1.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 2.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 2.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 1.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 5.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 7.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 2.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 3.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 4.3 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 0.3 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 4.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.7 GO:0036122 BMP binding(GO:0036122)
0.1 1.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.1 GO:0031267 small GTPase binding(GO:0031267)
0.1 9.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 3.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 12.5 GO:0060090 binding, bridging(GO:0060090)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.1 2.1 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 6.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 6.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 2.5 GO:0019901 protein kinase binding(GO:0019901)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 6.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.2 2.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 4.9 PID RAS PATHWAY Regulation of Ras family activation
0.2 3.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 2.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 4.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 4.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 1.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 3.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 3.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.5 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex