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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for bcl6aa+bcl6ab+bcl6b

Z-value: 0.86

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Transcription factors associated with bcl6aa+bcl6ab+bcl6b

Gene Symbol Gene ID Gene Info
bcl6ab
ENSDARG00000069295 BCL6A transcription repressor b
bcl6b
ENSDARG00000069335 BCL6B transcription repressor
bcl6aa
ENSDARG00000070864 BCL6A transcription repressor a
bcl6aa
ENSDARG00000111395 BCL6A transcription repressor a
bcl6aa
ENSDARG00000112502 BCL6A transcription repressor a
bcl6aa
ENSDARG00000116260 BCL6A transcription repressor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl6abdr11_v1_chr2_-_10098191_100981910.171.1e-01Click!
bcl6adr11_v1_chr6_-_28222592_28222592-0.122.5e-01Click!
bcl6bdr11_v1_chr7_+_20017211_20017211-0.084.6e-01Click!

Activity profile of bcl6aa+bcl6ab+bcl6b motif

Sorted Z-values of bcl6aa+bcl6ab+bcl6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_11457500 10.68 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr16_-_36834505 10.08 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr11_-_8167799 9.01 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
uox
urate oxidase
chr5_-_63509581 8.08 ENSDART00000097325
c5
complement component 5
chr25_-_17395315 7.07 ENSDART00000064596
cyp2x8
cytochrome P450, family 2, subfamily X, polypeptide 8
chr15_+_20239141 6.78 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr5_+_28849155 6.76 ENSDART00000079090
zgc:174259
zgc:174259
chr12_-_4243268 6.55 ENSDART00000131275
zgc:92313
zgc:92313
chr21_-_26114886 6.52 ENSDART00000139320
nipal4
NIPA-like domain containing 4
chr20_+_23440632 6.35 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr20_+_25581627 6.32 ENSDART00000030229
cyp2p9
cytochrome P450, family 2, subfamily P, polypeptide 9
chr16_-_45917322 6.20 ENSDART00000060822
afp4
antifreeze protein type IV
chr3_-_57737913 5.89 ENSDART00000113309
LGALS3BP (1 of many)
zgc:112492
chr19_-_5351980 5.60 ENSDART00000163304
ENSDART00000027701
krt92
keratin 92
chr24_-_2829049 5.56 ENSDART00000164913
PPP1R3G
si:ch211-152c8.5
chr3_+_19299309 5.46 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr5_+_28858345 4.89 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr16_-_27749172 4.41 ENSDART00000145198
steap4
STEAP family member 4
chr3_+_49021079 4.30 ENSDART00000162012
zgc:163083
zgc:163083
chr15_-_23793641 4.29 ENSDART00000122891
tmem97
transmembrane protein 97
chr20_+_25552057 4.23 ENSDART00000102913
cyp2v1
cytochrome P450, family 2, subfamily V, polypeptide 1
chr20_-_25551676 4.10 ENSDART00000063081
cyp2ad3
cytochrome P450, family 2, subfamily AD, polypeptide 3
chr23_+_42292748 4.10 ENSDART00000166113
ENSDART00000158684
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr11_+_14286160 4.05 ENSDART00000166236
si:ch211-262i1.3
si:ch211-262i1.3
chr5_+_24179307 3.95 ENSDART00000051552
mpdu1a
mannose-P-dolichol utilization defect 1a
chr4_-_12323228 3.93 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr6_-_8498908 3.89 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr11_+_43375326 3.87 ENSDART00000130131
sult6b1
sulfotransferase family, cytosolic, 6b, member 1
chr8_+_1189798 3.76 ENSDART00000193474
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr18_+_18863167 3.63 ENSDART00000091094
pllp
plasmolipin
chr18_-_14860435 3.63 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr8_+_47099033 3.58 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr23_+_42346799 3.25 ENSDART00000159985
ENSDART00000172144
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr8_+_22359881 3.24 ENSDART00000187867
zgc:153631
zgc:153631
chr7_-_19168375 3.22 ENSDART00000112447
il13ra1
interleukin 13 receptor, alpha 1
chr18_+_18982077 3.19 ENSDART00000006300
hacd3
3-hydroxyacyl-CoA dehydratase 3
chr13_+_33688474 3.15 ENSDART00000161465
CABZ01087953.1

chr6_-_8498676 3.11 ENSDART00000148627
pglyrp2
peptidoglycan recognition protein 2
chr17_+_10318071 3.00 ENSDART00000161844
foxa1
forkhead box A1
chr20_-_33704753 2.94 ENSDART00000157427
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr2_-_10703621 2.84 ENSDART00000005944
rpl5a
ribosomal protein L5a
chr25_-_29415369 2.82 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr3_-_44059902 2.69 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr24_-_33291784 2.62 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr3_-_50998577 2.61 ENSDART00000157735
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr14_-_11507211 2.53 ENSDART00000186873
ENSDART00000109181
ENSDART00000186166
ENSDART00000186986
zgc:174917
zgc:174917
chr7_+_61764040 2.49 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr18_+_44532370 2.48 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr7_+_14005111 2.37 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr3_+_3139240 2.37 ENSDART00000105014
si:dkey-30g5.1
si:dkey-30g5.1
chr2_-_11120220 2.36 ENSDART00000184793
cryz
crystallin, zeta (quinone reductase)
chr7_+_37372479 2.33 ENSDART00000173652
sall1a
spalt-like transcription factor 1a
chr21_-_17956416 2.32 ENSDART00000026737
stx2a
syntaxin 2a
chr7_+_26549846 2.32 ENSDART00000141353
tnk1
tyrosine kinase, non-receptor, 1
chr22_-_15578402 2.28 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr22_+_7480465 2.26 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr1_-_46663997 2.23 ENSDART00000134450
ebpl
emopamil binding protein-like
chr21_+_12010505 2.22 ENSDART00000123522
aqp7
aquaporin 7
chr22_-_16180467 2.17 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr4_-_18436899 2.13 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr2_+_35595454 2.09 ENSDART00000098734
cacybp
calcyclin binding protein
chr9_+_40825065 2.08 ENSDART00000137673
si:dkey-95p16.2
si:dkey-95p16.2
chr16_+_42772678 2.07 ENSDART00000155575
si:ch211-135n15.2
si:ch211-135n15.2
chr5_-_29195063 2.06 ENSDART00000109926
man1b1b
mannosidase, alpha, class 1B, member 1b
chr7_+_26167420 2.06 ENSDART00000173941
si:ch211-196f2.6
si:ch211-196f2.6
chr11_-_287670 2.05 ENSDART00000035737
slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr17_+_34206167 2.04 ENSDART00000136167
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr18_+_22109379 2.00 ENSDART00000147230
zgc:158868
zgc:158868
chr15_-_20709289 1.99 ENSDART00000136767
tpst1
tyrosylprotein sulfotransferase 1
chr20_-_19858936 1.97 ENSDART00000161579
ptk2bb
protein tyrosine kinase 2 beta, b
chr8_-_23240156 1.95 ENSDART00000131632
ptk6a
PTK6 protein tyrosine kinase 6a
chr6_+_28294113 1.94 ENSDART00000136898
lpp
LIM domain containing preferred translocation partner in lipoma
chr12_-_23365737 1.94 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr22_+_26400519 1.90 ENSDART00000159839
ENSDART00000144585
capn8
calpain 8
chr3_-_44012748 1.88 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr19_-_35428815 1.87 ENSDART00000169006
ENSDART00000003167
ak2
adenylate kinase 2
chr20_-_40367493 1.84 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr15_-_3282220 1.81 ENSDART00000092942
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr7_-_54320088 1.80 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr8_+_23711842 1.79 ENSDART00000128783
ppardb
peroxisome proliferator-activated receptor delta b
chr8_-_21091961 1.75 ENSDART00000100281
aldh9a1a.2
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2
chr10_-_3332362 1.75 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr2_-_37465517 1.74 ENSDART00000139983
si:dkey-57k2.6
si:dkey-57k2.6
chr9_-_17417628 1.74 ENSDART00000060425
ENSDART00000141997
ftr53
finTRIM family, member 53
chr24_+_11381400 1.74 ENSDART00000058703
ackr4b
atypical chemokine receptor 4b
chr18_-_46183462 1.73 ENSDART00000021192
kcnk6
potassium channel, subfamily K, member 6
chr25_+_11281970 1.71 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr17_-_23631400 1.69 ENSDART00000079563
fas
Fas cell surface death receptor
chr20_+_52458765 1.69 ENSDART00000057980
tsta3
tissue specific transplantation antigen P35B
chr20_-_23656516 1.66 ENSDART00000149735
cbr4
carbonyl reductase 4
chr19_+_4038589 1.64 ENSDART00000169271
btr23
bloodthirsty-related gene family, member 23
chr1_-_40208237 1.64 ENSDART00000191987
AL953865.1

chr18_+_44532199 1.61 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr5_+_50953240 1.61 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr16_-_26296477 1.60 ENSDART00000157553
erfl1
Ets2 repressor factor like 1
chr6_-_40352215 1.60 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr4_+_47257854 1.59 ENSDART00000173868
crestin
crestin
chr20_+_25625872 1.53 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr21_-_30026359 1.53 ENSDART00000153645
pwwp2a
PWWP domain containing 2A
chr19_-_3821678 1.53 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr23_+_45229198 1.51 ENSDART00000172445
ttc39b
tetratricopeptide repeat domain 39B
chr17_-_30521043 1.50 ENSDART00000087111
itsn2b
intersectin 2b
chr9_+_20869166 1.49 ENSDART00000147892
wdr3
WD repeat domain 3
chr19_+_32856907 1.48 ENSDART00000148232
rpl30
ribosomal protein L30
chr7_+_26029672 1.48 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr17_+_16046314 1.45 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr1_-_26026956 1.45 ENSDART00000102346
si:ch211-145b13.6
si:ch211-145b13.6
chr8_-_41228530 1.44 ENSDART00000165949
ENSDART00000173055
fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr13_-_37122217 1.43 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr6_-_35106425 1.42 ENSDART00000165139
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr18_+_45666489 1.41 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_-_8798178 1.39 ENSDART00000188232
cers2a
ceramide synthase 2a
chr25_-_34280080 1.38 ENSDART00000085251
gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_10318089 1.37 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr1_-_9195629 1.36 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr2_+_111919 1.36 ENSDART00000149391
fggy
FGGY carbohydrate kinase domain containing
chr17_+_16046132 1.35 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr4_+_73215536 1.35 ENSDART00000174290
LO018260.2
Danio rerio protein NLRC3-like (LOC101883187), mRNA.
chr3_+_32492467 1.33 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr3_+_60589157 1.33 ENSDART00000165367
mettl23
methyltransferase like 23
chr9_-_9225980 1.32 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr25_-_21822426 1.32 ENSDART00000151993
zgc:158222
zgc:158222
chr16_-_42965192 1.31 ENSDART00000113714
mtx1a
metaxin 1a
chr14_+_26229056 1.31 ENSDART00000179045
LO018208.1

chr16_-_41667101 1.30 ENSDART00000084528
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr1_-_44928987 1.29 ENSDART00000134635
si:dkey-9i23.15
si:dkey-9i23.15
chr2_-_59327299 1.29 ENSDART00000133734
ftr36
finTRIM family, member 36
chr13_-_11967769 1.28 ENSDART00000158369
ARL3 (1 of many)
zgc:110197
chr5_+_9360394 1.28 ENSDART00000124642
FP236810.2

chr3_+_1698430 1.27 ENSDART00000193625
BX321875.4

chr15_+_19324697 1.23 ENSDART00000022015
vps26b
VPS26 retromer complex component B
chr7_-_34434889 1.21 ENSDART00000159982
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr12_+_5358409 1.20 ENSDART00000152632
plce1
phospholipase C, epsilon 1
chr17_-_12498096 1.20 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr7_+_32369026 1.20 ENSDART00000169588
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr18_-_44888375 1.19 ENSDART00000160506
si:ch211-71n6.4
si:ch211-71n6.4
chr13_-_47554194 1.18 ENSDART00000181508
acoxl
acyl-CoA oxidase-like
chr4_+_57580303 1.16 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
il17ra1b
il17ra2
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr9_-_43644261 1.16 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr24_+_7828097 1.15 ENSDART00000134975
zgc:101569
zgc:101569
chr21_+_26073104 1.15 ENSDART00000193273
rpl23a
ribosomal protein L23a
chr18_+_13315739 1.12 ENSDART00000143404
si:ch211-260p9.3
si:ch211-260p9.3
chr5_+_1911814 1.10 ENSDART00000172233
si:ch73-55i23.1
si:ch73-55i23.1
chr16_+_46294337 1.10 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr8_-_23783633 1.09 ENSDART00000132657
si:ch211-163l21.7
si:ch211-163l21.7
chr25_+_16915974 1.07 ENSDART00000188923
zgc:77158
zgc:77158
chr5_+_19494198 1.07 ENSDART00000006673
mvk
mevalonate kinase
chr1_-_40189893 1.06 ENSDART00000133738
si:ch211-113e8.6
si:ch211-113e8.6
chr4_+_49322310 1.06 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr11_+_36409457 1.05 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr6_+_47843760 1.01 ENSDART00000140943
padi2
peptidyl arginine deiminase, type II
chr22_-_37611681 1.00 ENSDART00000028085
ttc14
tetratricopeptide repeat domain 14
chr17_-_48743076 0.98 ENSDART00000173117
kcnk17
potassium channel, subfamily K, member 17
chr5_-_51166025 0.95 ENSDART00000097471
card9
caspase recruitment domain family, member 9
chr2_+_3428357 0.95 ENSDART00000125967
CU633991.1

chr18_+_14684115 0.94 ENSDART00000108469
spata2l
spermatogenesis associated 2-like
chr12_-_26558038 0.94 ENSDART00000039510
tap2t
transporter associated with antigen processing, subunit type t, teleost specific
chr1_-_56596701 0.94 ENSDART00000133693
LO018605.1

chr20_+_21595244 0.93 ENSDART00000010643
esr2a
estrogen receptor 2a
chr9_-_38579758 0.92 ENSDART00000131738
si:dkey-101k6.5
si:dkey-101k6.5
chr21_+_45626136 0.91 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr23_-_19715799 0.90 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr16_-_4610255 0.90 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr17_+_24597001 0.90 ENSDART00000191834
rlf
rearranged L-myc fusion
chr20_+_4793790 0.89 ENSDART00000153486
lgals8a
galectin 8a
chr21_-_27338639 0.88 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr22_-_27706576 0.88 ENSDART00000188564
CR547131.1

chr12_-_44151296 0.87 ENSDART00000168734
si:ch73-329n5.3
si:ch73-329n5.3
chr1_-_57839070 0.87 ENSDART00000152571
si:dkey-1c7.3
si:dkey-1c7.3
chr3_-_54524194 0.86 ENSDART00000155406
ENSDART00000111791
si:ch73-208g10.1
si:ch73-208g10.1
chr13_-_37631092 0.86 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
chr23_-_14830627 0.86 ENSDART00000134659
sla2
Src-like-adaptor 2
chr21_+_27297145 0.84 ENSDART00000146588
si:dkey-175m17.6
si:dkey-175m17.6
chr7_-_24373662 0.84 ENSDART00000173865
PTGR1 (1 of many)
si:dkey-11k2.7
chr3_-_55139127 0.83 ENSDART00000115324
hbae1.3
hemoglobin, alpha embryonic 1.3
chr4_+_57099307 0.83 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr9_+_26103814 0.83 ENSDART00000026011
efnb2a
ephrin-B2a
chr1_+_58139102 0.82 ENSDART00000134826
si:ch211-15j1.4
si:ch211-15j1.4
chr17_-_50430817 0.82 ENSDART00000154007
si:ch211-235i11.4
si:ch211-235i11.4
chr20_+_27087539 0.82 ENSDART00000062094
tmem251
transmembrane protein 251
chr13_-_50234122 0.81 ENSDART00000164338
eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr5_-_35200590 0.80 ENSDART00000051271
fcho2
FCH domain only 2
chr5_-_41841675 0.80 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr3_-_30888415 0.79 ENSDART00000124458
kmt5c
lysine methyltransferase 5C
chr4_+_6639292 0.79 ENSDART00000158573
SMIM30
si:dkey-112e7.2
chr22_-_3344613 0.78 ENSDART00000165600
tbxa2r
thromboxane A2 receptor
chr16_+_40954481 0.77 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr3_-_3703572 0.77 ENSDART00000111017
si:ch211-163m16.7
si:ch211-163m16.7
chr6_-_14004772 0.77 ENSDART00000185629
zgc:92027
zgc:92027
chr6_+_41503854 0.76 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr14_-_5678457 0.76 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr19_-_6631900 0.76 ENSDART00000144571
pvrl2l
poliovirus receptor-related 2 like
chr18_-_21170264 0.74 ENSDART00000175265
BX571884.1

chr7_-_12869545 0.74 ENSDART00000163045
sh3gl3a
SH3-domain GRB2-like 3a
chr1_+_55600504 0.74 ENSDART00000123946
umod
uromodulin
chr10_-_39281475 0.73 ENSDART00000175136
cry5
cryptochrome circadian clock 5
chr4_-_13518381 0.73 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr20_+_27646772 0.72 ENSDART00000141697
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr7_+_73295890 0.71 ENSDART00000174331
ENSDART00000174250
CABZ01083442.1

chr7_+_32369463 0.71 ENSDART00000180544
lgr4
leucine-rich repeat containing G protein-coupled receptor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl6aa+bcl6ab+bcl6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
2.3 7.0 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
1.1 4.6 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
1.1 4.4 GO:0015677 copper ion import(GO:0015677)
0.9 3.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.9 5.5 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.7 2.1 GO:0002857 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.6 1.8 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.6 4.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 28.5 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.5 2.1 GO:0010039 response to iron ion(GO:0010039)
0.5 2.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.5 1.8 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 1.3 GO:0002369 T cell cytokine production(GO:0002369)
0.4 1.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.4 1.7 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.4 1.2 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.4 6.5 GO:0015693 magnesium ion transport(GO:0015693)
0.4 1.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 0.4 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.4 2.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 2.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 3.2 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.3 1.9 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.3 0.9 GO:1990403 embryonic brain development(GO:1990403)
0.3 3.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.3 8.1 GO:0060030 dorsal convergence(GO:0060030)
0.3 1.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.3 1.9 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.3 1.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 0.8 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.3 2.6 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 1.3 GO:0055071 manganese ion homeostasis(GO:0055071)
0.3 1.3 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 2.0 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.2 2.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.2 1.0 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 1.8 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.2 2.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 3.9 GO:0051923 sulfation(GO:0051923)
0.2 1.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 4.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.7 GO:0099563 modification of synaptic structure(GO:0099563)
0.2 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 0.8 GO:0007412 axon target recognition(GO:0007412)
0.2 0.6 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.2 2.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 1.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 2.0 GO:0007172 signal complex assembly(GO:0007172)
0.1 2.6 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 3.0 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 11.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.5 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 3.2 GO:0030497 fatty acid elongation(GO:0030497)
0.1 1.5 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.7 GO:0051883 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.5 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 0.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.9 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.6 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 3.7 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 0.9 GO:0002831 regulation of response to biotic stimulus(GO:0002831)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.5 GO:0031179 peptide modification(GO:0031179)
0.1 0.8 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 1.0 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.2 GO:1905067 negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.8 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 1.9 GO:0007586 digestion(GO:0007586)
0.1 0.5 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.6 GO:0006999 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 0.9 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 1.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.8 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 2.2 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.2 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 1.1 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 9.0 GO:0006914 autophagy(GO:0006914)
0.0 1.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0035474 selective angioblast sprouting(GO:0035474) angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 1.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 2.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.6 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.4 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 7.9 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 3.2 GO:0016485 protein processing(GO:0016485)
0.0 0.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 1.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.3 GO:0051607 defense response to virus(GO:0051607)
0.0 0.7 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.5 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.7 GO:0007548 sex differentiation(GO:0007548)
0.0 0.1 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 1.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.5 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.2 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 1.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.2 GO:0030904 retromer complex(GO:0030904)
0.1 0.4 GO:0016600 flotillin complex(GO:0016600)
0.1 6.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 2.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 2.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.7 GO:0035060 brahma complex(GO:0035060)
0.1 0.2 GO:0045334 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669) clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 4.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 5.5 GO:0005882 intermediate filament(GO:0005882)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 5.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 12.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 5.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 5.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.8 GO:0005930 axoneme(GO:0005930)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 1.7 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 15.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0044440 endosomal part(GO:0044440)
0.0 1.7 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.4 5.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.1 9.0 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
1.1 10.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.1 4.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.9 3.8 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.8 3.2 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.8 2.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.7 3.7 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.7 2.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.6 2.8 GO:0008097 5S rRNA binding(GO:0008097)
0.5 1.6 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.5 2.1 GO:0044548 S100 protein binding(GO:0044548)
0.4 28.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.4 1.7 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.4 1.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.4 5.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 2.9 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3 1.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.3 6.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.0 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.3 2.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 0.9 GO:0046978 TAP1 binding(GO:0046978)
0.3 2.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.3 2.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 0.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 1.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 2.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 0.7 GO:0003913 DNA photolyase activity(GO:0003913)
0.2 3.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 2.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 2.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 1.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 1.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.0 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.1 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.7 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.9 GO:1903924 estradiol binding(GO:1903924)
0.1 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 1.8 GO:0002020 protease binding(GO:0002020)
0.1 0.6 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 20.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.2 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 9.5 GO:0019955 cytokine binding(GO:0019955)
0.1 6.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0019809 spermidine binding(GO:0019809)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.5 GO:0048038 quinone binding(GO:0048038)
0.1 1.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 1.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 12.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 2.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 3.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.3 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 2.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.9 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 3.0 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 2.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 3.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.5 2.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 8.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 0.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 3.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 3.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 5.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 3.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D