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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for cdc5l

Z-value: 1.19

Motif logo

Transcription factors associated with cdc5l

Gene Symbol Gene ID Gene Info
ENSDARG00000043797 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cdc5ldr11_v1_chr17_+_5061135_50611350.462.5e-06Click!

Activity profile of cdc5l motif

Sorted Z-values of cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_33606739 10.68 ENSDART00000026464
cofilin 1 (non-muscle), like
chr1_-_45177373 7.72 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr18_+_7591381 6.52 ENSDART00000136313
si:dkeyp-1h4.6
chr15_-_12360409 6.04 ENSDART00000164596
transmembrane protease, serine 13a
chr24_-_26310854 5.97 ENSDART00000080113
apolipoprotein Db
chr7_+_14291323 5.27 ENSDART00000053521
Rh family, C glycoprotein a
chr12_-_30549022 4.98 ENSDART00000102474
zgc:158404
chr16_-_46567344 4.77 ENSDART00000127721
si:dkey-152b24.7
chr6_-_49063085 4.39 ENSDART00000156124
si:ch211-105j21.9
chr3_+_62161184 4.18 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr3_+_32842825 4.00 ENSDART00000122228
proline rich 14
chr4_-_11580948 3.71 ENSDART00000049066
neuroepithelial cell transforming 1
chr14_-_36763302 3.67 ENSDART00000074786
cathepsin O
chr17_-_32426392 3.62 ENSDART00000148455
ENSDART00000149885
ENSDART00000179314
grainyhead-like transcription factor 1
chr5_-_55560937 3.60 ENSDART00000148436
guanine nucleotide binding protein (G protein), alpha 14
chr19_+_2835240 3.48 ENSDART00000190838
CUB domain containing protein 1
chr2_-_23390779 3.35 ENSDART00000020136
influenza virus NS1A binding protein b
chr1_-_12161148 3.30 ENSDART00000166429
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr7_+_24881680 3.30 ENSDART00000058843
kelch repeat-containing protein
chr15_+_28410664 3.29 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr16_-_25699554 3.23 ENSDART00000155899
ENSDART00000114495
DEAD (Asp-Glu-Ala-Asp) box helicase 61
chr3_-_61162750 3.18 ENSDART00000055064
parvalbumin 8
chr24_-_31904924 3.17 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr18_-_18874921 3.16 ENSDART00000193332
ADP-ribosylation factor-like 2 binding protein
chr24_+_31277360 3.16 ENSDART00000165993
coagulation factor IIIa
chr10_+_3428194 3.13 ENSDART00000081599
protein tyrosine phosphatase, non-receptor type 11, a
chr7_-_28647959 3.11 ENSDART00000150148
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr2_-_47620806 3.09 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr19_-_13933204 3.05 ENSDART00000158059
tRNA selenocysteine 1 associated protein 1a
chr13_+_18321140 3.04 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr18_-_6943577 3.03 ENSDART00000132399
si:dkey-266m15.6
chr20_+_43691208 3.00 ENSDART00000152976
ENSDART00000045185
lin-9 DREAM MuvB core complex component
chr10_+_8656417 2.98 ENSDART00000123131
phorbol-12-myristate-13-acetate-induced protein 1
chr6_+_40922572 2.88 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_+_45007962 2.86 ENSDART00000010786
doublesex and mab-3 related transcription factor 2a
chr18_+_36631923 2.83 ENSDART00000098980
zinc finger protein 296
chr16_+_29509133 2.81 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr11_-_6880725 2.80 ENSDART00000007204
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr23_-_23179417 2.79 ENSDART00000122945
ENSDART00000091662
NOC2-like nucleolar associated transcriptional repressor
chr10_-_22918214 2.78 ENSDART00000163908
ribonuclease, RNase K b
chr4_-_76370630 2.76 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
chr17_-_14700889 2.76 ENSDART00000179975
protein tyrosine phosphatase type IVA, member 2a
chr18_-_29925717 2.73 ENSDART00000099281
major histocompatibility complex class II DBB gene
chr19_-_31372896 2.70 ENSDART00000046609
scinderin
chr1_-_52447364 2.68 ENSDART00000140740
si:ch211-217k17.10
chr2_+_2168547 2.66 ENSDART00000029347
HIG1 hypoxia inducible domain family, member 1A
chr6_+_29386728 2.66 ENSDART00000104303
actin-like 6A
chr24_-_23784701 2.63 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr2_+_10280645 2.63 ENSDART00000063996
growth arrest and DNA-damage-inducible, alpha, a
chr3_-_54607166 2.61 ENSDART00000021977
DNA (cytosine-5-)-methyltransferase 1
chr18_+_31073265 2.59 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr5_-_37117778 2.56 ENSDART00000149138
interleukin 13 receptor, alpha 2
chr11_-_16152400 2.55 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr2_-_8648440 2.52 ENSDART00000135743
si:ch211-71m22.3
chr9_+_34397843 2.52 ENSDART00000146314
mediator complex subunit 14
chr8_-_36370552 2.52 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
chr12_+_5708400 2.51 ENSDART00000017191
distal-less homeobox 3b
chr8_+_39674707 2.50 ENSDART00000126301
ENSDART00000040330
protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
chr1_-_58064738 2.49 ENSDART00000073778
caspase b
chr8_-_13010011 2.48 ENSDART00000140969
DENN/MADD domain containing 2Da
chr2_-_2623983 2.47 ENSDART00000190568

chr19_+_3056450 2.46 ENSDART00000141324
ENSDART00000082353
heat shock transcription factor 1
chr3_-_16537441 2.46 ENSDART00000080749
ENSDART00000133824
eps8-like1
chr12_+_30367371 2.45 ENSDART00000153364
si:ch211-225b10.4
chr10_+_13209580 2.43 ENSDART00000000887
ENSDART00000136932
Ras association (RalGDS/AF-6) domain family 6
chr23_-_14825450 2.42 ENSDART00000188009
Src-like-adaptor 2
chr17_+_6563307 2.40 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr1_-_12160981 2.38 ENSDART00000162146
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr9_-_9415000 2.38 ENSDART00000146210
si:ch211-214p13.9
chr4_+_3358383 2.37 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr8_-_36140405 2.37 ENSDART00000182806

chr22_-_10580194 2.36 ENSDART00000105848
si:dkey-42i9.7
chr16_-_52540056 2.35 ENSDART00000188304

chr3_+_22375596 2.31 ENSDART00000188243
ENSDART00000181506
Rho GTPase activating protein 27, like
chr19_+_7636941 2.30 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr9_+_34397516 2.29 ENSDART00000011304
ENSDART00000192973
mediator complex subunit 14
chr25_-_12805295 2.29 ENSDART00000157629
carbonic anhydrase Va
chr8_+_47099033 2.28 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr10_-_33251876 2.28 ENSDART00000184565
BCL tumor suppressor 7Ba
chr6_-_37745508 2.27 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr15_+_3808996 2.24 ENSDART00000110227
ring finger protein 14
chr23_+_37458602 2.22 ENSDART00000181686
cytidine deaminase a
chr20_+_26394324 2.18 ENSDART00000078093
zinc finger and BTB domain containing 2b
chr20_-_29787192 2.17 ENSDART00000125348
ENSDART00000048759
inhibitor of DNA binding 2b
chr16_+_35916371 2.17 ENSDART00000167208
SH3 domain containing 21
chr6_+_25213934 2.15 ENSDART00000163440
si:ch73-97h19.2
chr5_-_40024902 2.15 ENSDART00000017451
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_+_2169337 2.13 ENSDART00000179939
HIG1 hypoxia inducible domain family, member 1A
chr5_+_50879545 2.12 ENSDART00000128402
nucleolar protein 6 (RNA-associated)
chr17_-_27273296 2.11 ENSDART00000077087
inhibitor of DNA binding 3
chr25_-_3217115 2.10 ENSDART00000032390
general transcription factor IIH, polypeptide 1
chr23_-_25798099 2.09 ENSDART00000041833
fat storage-inducing transmembrane protein 2
chr20_+_23238833 2.08 ENSDART00000074167
OCIA domain containing 2
chr1_-_53880639 2.07 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr1_+_9966384 2.07 ENSDART00000132607
si:dkeyp-75b4.8
chr3_-_55537096 2.07 ENSDART00000123544
ENSDART00000188752
testis expressed 2
chr22_+_14117078 2.05 ENSDART00000013575
basic leucine zipper and W2 domains 1a
chr1_-_38171648 2.05 ENSDART00000137451
ENSDART00000047159
high mobility group box 2a
chr11_-_16152105 2.05 ENSDART00000081062
actin related protein 2/3 complex, subunit 4, like
chr24_+_27511734 2.04 ENSDART00000105771
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr8_+_28358161 2.04 ENSDART00000062682
adiponectin receptor 1b
chr6_+_13506841 2.04 ENSDART00000032331
GDP-mannose pyrophosphorylase Ab
chr25_-_22191983 2.04 ENSDART00000191181
plakophilin 3a
chr4_+_25181572 2.01 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr9_+_38043337 2.01 ENSDART00000022574
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr21_+_15295685 2.00 ENSDART00000135603

chr15_+_20529197 1.99 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr5_+_21181047 1.99 ENSDART00000088506
Rho GTPase activating protein 25
chr23_+_32011768 1.99 ENSDART00000053509
pleiomorphic adenoma gene X
chr21_-_43457554 1.98 ENSDART00000085039
serine/threonine protein kinase 26
chr16_+_21789703 1.97 ENSDART00000153617
tripartite motif containing 108
chr2_-_40890264 1.97 ENSDART00000123886
UDP-glucose glycoprotein glucosyltransferase 1
chr25_+_17925424 1.94 ENSDART00000067305
zgc:103499
chr17_-_21418340 1.94 ENSDART00000007021
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr25_-_13614863 1.93 ENSDART00000121859
fatty acid 2-hydroxylase
chr10_-_35153388 1.92 ENSDART00000188132
receptor-interacting serine-threonine kinase 4
chr8_+_26292560 1.92 ENSDART00000053463
monoglyceride lipase
chr6_-_41091151 1.91 ENSDART00000154963
ENSDART00000153818
serine/arginine-rich splicing factor 3a
chr3_+_32651697 1.91 ENSDART00000055338
THO complex 6
chr3_-_26921475 1.91 ENSDART00000130281
class II, major histocompatibility complex, transactivator
chr3_-_54846444 1.90 ENSDART00000074010
UBA-like domain containing 1b
chr24_+_12989727 1.90 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr18_+_13203831 1.90 ENSDART00000032151
coactosin-like F-actin binding protein 1
chr24_-_8409641 1.90 ENSDART00000149662
ENSDART00000149025
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr19_+_8985230 1.88 ENSDART00000018973
secretory carrier membrane protein 3
chr16_+_19637384 1.88 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr5_-_19006290 1.88 ENSDART00000137022
golgin A3
chr2_-_19234329 1.88 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cell division cycle 20 homolog
chr20_-_38801981 1.87 ENSDART00000125333
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_+_45008418 1.86 ENSDART00000189882
doublesex and mab-3 related transcription factor 2a
chr17_-_31695217 1.86 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr8_+_45003659 1.86 ENSDART00000132663
si:ch211-163b2.4
chr8_-_10947205 1.85 ENSDART00000164467
PQ loop repeat containing 2
chr12_-_7253270 1.85 ENSDART00000035762
ubiquitin-conjugating enzyme E2D 1b
chr12_-_30548244 1.84 ENSDART00000193616
zgc:158404
chr16_-_32208728 1.83 ENSDART00000023995
calcium homeostasis modulator family member 5, tandem duplicate 2
chr19_-_12193622 1.80 ENSDART00000041960
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr13_+_7241170 1.78 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr15_-_34892664 1.78 ENSDART00000153787
ENSDART00000099721
ring finger protein 183
chr2_+_31671545 1.78 ENSDART00000145446
atypical chemokine receptor 4a
chr6_+_23712911 1.77 ENSDART00000167795
zgc:158654
chr1_-_18848955 1.77 ENSDART00000109294
ENSDART00000146410
zgc:195282
chr10_+_22918338 1.76 ENSDART00000167874
ENSDART00000171298
zgc:103508
chr18_-_18875308 1.75 ENSDART00000127182
ADP-ribosylation factor-like 2 binding protein
chr19_-_27542277 1.75 ENSDART00000114301
si:ch211-152p11.4
chr19_-_27542433 1.75 ENSDART00000136414
si:ch211-152p11.4
chr10_-_41907213 1.75 ENSDART00000167004
lysine (K)-specific demethylase 2Bb
chr18_-_7137153 1.75 ENSDART00000019571
CD9 molecule a
chr6_-_8244474 1.73 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr23_+_28381260 1.72 ENSDART00000162722
zgc:153867
chr2_-_58257624 1.71 ENSDART00000098940
forkhead box L2b
chr6_-_57408576 1.71 ENSDART00000163930
zinc finger, NFX1-type containing 1
chr23_+_37086159 1.71 ENSDART00000074407
ceramide-1-phosphate transfer protein
chr22_-_8388678 1.70 ENSDART00000184389

chr23_-_16692312 1.70 ENSDART00000046784
FK506 binding protein 1Ab
chr5_+_48666485 1.70 ENSDART00000158000
ENSDART00000031141
polymerase (RNA) III (DNA directed) polypeptide G
chr1_+_25178106 1.69 ENSDART00000054265
ENSDART00000141648
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr24_-_21172122 1.69 ENSDART00000154259
ATPase H+ transporting V1 subunit Ab
chr7_+_18106727 1.69 ENSDART00000190307
zRAB1B, member RAS oncogene family a
chr10_-_1733937 1.68 ENSDART00000144216
galactose-3-O-sulfotransferase 1b
chr19_+_7045033 1.68 ENSDART00000146579
major histocompatibility complex class I UKA
chr13_-_42757565 1.67 ENSDART00000161950
calpain 2, (m/II) large subunit a
chr12_+_30367079 1.66 ENSDART00000190112
si:ch211-225b10.4
chr13_+_42011287 1.65 ENSDART00000131147
cytochrome P450, family 1, subfamily B, polypeptide 1
chr1_+_12394205 1.65 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
chr16_-_42965192 1.65 ENSDART00000113714
metaxin 1a
chr5_-_52964789 1.64 ENSDART00000166267
zinc finger protein-like 1
chr18_-_46354269 1.64 ENSDART00000010813
forkhead box A3
chr6_-_30683637 1.64 ENSDART00000065212
tetratricopeptide repeat domain 4
chr5_+_20366453 1.63 ENSDART00000193141
coronin, actin binding protein, 1Ca
chr16_+_24978203 1.63 ENSDART00000156579
si:dkeyp-84f3.5
chr3_-_31086770 1.63 ENSDART00000103421
zgc:153292
chr16_-_11859309 1.63 ENSDART00000145754
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr4_-_17812131 1.62 ENSDART00000025731
Spi-C transcription factor (Spi-1/PU.1 related)
chr4_+_17642731 1.62 ENSDART00000026509
CWF19-like 1, cell cycle control
chr16_-_33650578 1.62 ENSDART00000058460
UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
chr2_+_37295088 1.62 ENSDART00000056519
G protein-coupled receptor 160
chr3_-_7990516 1.61 ENSDART00000167877
si:ch211-175l6.2
chr22_+_30631072 1.61 ENSDART00000059970
zmp:0000000606
chr22_+_10166407 1.61 ENSDART00000092104
PX domain containing serine/threonine kinase
chr3_-_42125655 1.61 ENSDART00000040753
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr3_-_45308394 1.60 ENSDART00000155324
3-phosphoinositide dependent protein kinase 1a
chr1_+_9860381 1.59 ENSDART00000054848
phosphomannomutase 2
chr21_+_34033580 1.58 ENSDART00000100351
mitogen-activated protein kinase kinase kinase kinase 6
chr13_-_37474989 1.57 ENSDART00000114136
WD repeat domain 89
chr25_-_22889519 1.56 ENSDART00000128250
MOB kinase activator 2a
chr17_-_19463355 1.56 ENSDART00000045881
dicer 1, ribonuclease type III
chr21_-_18275226 1.56 ENSDART00000126672
ENSDART00000135239
bromodomain containing 3a
chr19_+_16064439 1.56 ENSDART00000151169
glucocorticoid modulatory element binding protein 1
chr12_+_1609563 1.55 ENSDART00000163559
solute carrier family 39 member 11
chr5_+_56277866 1.55 ENSDART00000170610
ENSDART00000028854
ENSDART00000148749
apoptosis antagonizing transcription factor
chr13_-_33639050 1.54 ENSDART00000133073
ribosome binding protein 1a
chr8_-_21052371 1.54 ENSDART00000136561
si:dkeyp-82a1.6
chr18_+_21122818 1.54 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr3_-_26244256 1.54 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr19_+_20163826 1.53 ENSDART00000090942
ENSDART00000134650
coiled-coil domain containing 126
chr10_+_39893439 1.53 ENSDART00000003435
small fragment nuclease
chr5_-_15494164 1.52 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr21_-_25612658 1.51 ENSDART00000115276
fibroblast growth factor (acidic) intracellular binding protein b
chr24_-_9294134 1.51 ENSDART00000082434
TGFB-induced factor homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.9 4.4 GO:0021559 trigeminal nerve development(GO:0021559)
0.8 4.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.7 2.2 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.7 2.8 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.7 2.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7 5.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.6 3.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.6 3.6 GO:0003334 keratinocyte development(GO:0003334)
0.6 1.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.5 1.6 GO:0048785 hatching gland development(GO:0048785)
0.5 1.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 2.6 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.5 1.6 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.5 1.4 GO:0021742 abducens nucleus development(GO:0021742)
0.5 2.7 GO:0032447 protein urmylation(GO:0032447)
0.5 5.9 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.4 1.3 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.4 2.1 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.4 1.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.4 3.2 GO:0034063 stress granule assembly(GO:0034063)
0.4 1.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.4 1.1 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.4 2.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 3.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.3 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.4 GO:0010039 response to iron ion(GO:0010039)
0.3 1.3 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.3 2.6 GO:0042554 superoxide anion generation(GO:0042554)
0.3 1.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.3 1.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.3 1.2 GO:0042148 strand invasion(GO:0042148)
0.3 0.9 GO:0015808 L-alanine transport(GO:0015808)
0.3 2.1 GO:0034389 lipid particle organization(GO:0034389)
0.3 3.0 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.3 0.9 GO:0060912 cardiac cell fate specification(GO:0060912)
0.3 2.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 0.8 GO:0045601 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.3 2.8 GO:0035065 regulation of histone acetylation(GO:0035065)
0.2 0.7 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.2 1.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 1.7 GO:0035627 ceramide transport(GO:0035627)
0.2 1.2 GO:2000301 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.2 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.9 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.9 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 4.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.2 1.0 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 3.7 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.2 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.2 2.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 1.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 6.2 GO:0007568 aging(GO:0007568)
0.2 1.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.5 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 1.0 GO:0019563 glycerol catabolic process(GO:0019563)
0.2 4.7 GO:0048570 notochord morphogenesis(GO:0048570)
0.2 0.5 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.2 1.0 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 1.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 0.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 2.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 3.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.3 GO:0036372 opsin transport(GO:0036372)
0.2 4.8 GO:0019827 stem cell population maintenance(GO:0019827)
0.2 2.6 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.2 0.3 GO:0045117 azole transport(GO:0045117)
0.2 0.9 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 1.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 2.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 0.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.4 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1 0.4 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 1.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 3.7 GO:0043967 histone H4 acetylation(GO:0043967)
0.1 1.0 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 1.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 2.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.7 GO:0009303 rRNA transcription(GO:0009303)
0.1 2.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.3 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.6 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.1 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 2.5 GO:0009408 response to heat(GO:0009408)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.7 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 2.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.4 GO:0065001 specification of axis polarity(GO:0065001)
0.1 1.3 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 1.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.5 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 2.8 GO:0051014 actin filament severing(GO:0051014)
0.1 2.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.4 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 2.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 2.0 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 0.5 GO:0034427 miRNA metabolic process(GO:0010586) nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 0.5 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.1 3.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.8 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 1.0 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 3.3 GO:0007548 sex differentiation(GO:0007548)
0.1 2.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 4.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.9 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 4.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.7 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 9.6 GO:0006413 translational initiation(GO:0006413)
0.1 1.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.9 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 2.6 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 0.8 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.7 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 2.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 2.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 2.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 2.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 1.6 GO:0090148 membrane fission(GO:0090148)
0.1 0.5 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 0.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.8 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.1 1.2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 0.9 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.1 1.9 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.1 0.5 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 4.3 GO:0007596 blood coagulation(GO:0007596)
0.1 1.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.2 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.6 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.5 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.1 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 1.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 1.1 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.1 3.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.5 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 1.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 1.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 5.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.4 GO:0051923 sulfation(GO:0051923)
0.0 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 2.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 3.1 GO:0051028 mRNA transport(GO:0051028)
0.0 2.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 2.0 GO:0016573 histone acetylation(GO:0016573)
0.0 0.6 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.7 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.5 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 1.3 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.3 GO:0071632 optomotor response(GO:0071632)
0.0 0.6 GO:1990798 pancreas regeneration(GO:1990798)
0.0 1.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 2.6 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 3.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.6 GO:0007338 single fertilization(GO:0007338)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.9 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 1.4 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.0 0.9 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 3.5 GO:0006260 DNA replication(GO:0006260)
0.0 3.5 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.9 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 2.6 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.0 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.8 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.9 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 5.8 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.8 GO:0016072 rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.0 1.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.6 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.2 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 2.7 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.9 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.8 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 1.6 GO:0006954 inflammatory response(GO:0006954)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.0 GO:0001891 phagocytic cup(GO:0001891)
0.9 2.8 GO:0030689 Noc complex(GO:0030689)
0.7 2.1 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.7 4.8 GO:0070847 core mediator complex(GO:0070847)
0.6 2.6 GO:0019815 B cell receptor complex(GO:0019815)
0.6 2.5 GO:0061702 inflammasome complex(GO:0061702)
0.5 1.6 GO:0070578 RISC-loading complex(GO:0070578)
0.5 1.0 GO:0097255 R2TP complex(GO:0097255)
0.5 1.4 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 1.4 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.4 1.3 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.4 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.4 1.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 1.5 GO:0033186 CAF-1 complex(GO:0033186)
0.4 3.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 1.1 GO:0034457 Mpp10 complex(GO:0034457)
0.3 2.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.4 GO:0017177 glucosidase II complex(GO:0017177)
0.3 2.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 2.1 GO:0000439 core TFIIH complex(GO:0000439)
0.3 4.2 GO:0002102 podosome(GO:0002102)
0.3 1.8 GO:0016589 NURF complex(GO:0016589)
0.3 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 1.3 GO:0005879 axonemal microtubule(GO:0005879)
0.3 4.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 1.2 GO:0034657 GID complex(GO:0034657)
0.2 1.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 1.1 GO:0018444 translation release factor complex(GO:0018444)
0.2 4.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 0.8 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 3.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 6.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 0.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 0.9 GO:0070724 BMP receptor complex(GO:0070724)
0.2 0.5 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.2 0.5 GO:0032301 MutSalpha complex(GO:0032301)
0.2 1.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 2.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.2 1.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 0.8 GO:0033263 CORVET complex(GO:0033263)
0.2 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.3 GO:0000796 condensin complex(GO:0000796)
0.2 3.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.2 GO:0032797 SMN complex(GO:0032797)
0.2 2.9 GO:0030057 desmosome(GO:0030057)
0.2 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.4 GO:0031526 brush border membrane(GO:0031526)
0.1 1.0 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.3 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.2 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.0 GO:0005903 brush border(GO:0005903)
0.1 0.8 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 4.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.8 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 8.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 4.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 4.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 1.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:0005771 multivesicular body(GO:0005771)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.1 1.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 4.4 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 3.7 GO:0001726 ruffle(GO:0001726)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 2.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.0 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 3.9 GO:0016607 nuclear speck(GO:0016607)
0.0 0.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 8.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.8 GO:0031201 SNARE complex(GO:0031201)
0.0 7.4 GO:0005764 lysosome(GO:0005764)
0.0 5.6 GO:0005819 spindle(GO:0005819)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 3.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 6.1 GO:0005730 nucleolus(GO:0005730)
0.0 1.7 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 1.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.8 2.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.8 3.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.6 1.9 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.6 1.9 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.6 3.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.6 1.8 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 2.0 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.5 4.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5 1.4 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.5 1.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 1.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.4 1.3 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.4 3.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.4 1.2 GO:0000150 recombinase activity(GO:0000150)
0.4 2.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 1.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 1.6 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.4 1.9 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.4 1.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.4 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 1.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.4 1.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 1.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 1.7 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.3 1.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 1.3 GO:0070513 death domain binding(GO:0070513)
0.3 1.0 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 2.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 0.9 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 1.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 2.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 2.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 0.9 GO:0042806 fucose binding(GO:0042806)
0.3 0.9 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.3 1.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 1.7 GO:0070330 aromatase activity(GO:0070330)
0.3 1.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.2 1.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 1.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 0.7 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 2.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 2.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 5.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 2.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 1.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.9 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 1.7 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 2.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 0.9 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.2 1.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.9 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.2 1.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.5 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.2 2.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 1.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.0 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.2 1.5 GO:0008494 translation activator activity(GO:0008494)
0.2 3.9 GO:0031267 small GTPase binding(GO:0031267)
0.2 1.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 1.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.8 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 5.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 2.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.8 GO:0019003 GDP binding(GO:0019003)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 2.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 3.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.8 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.3 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 4.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 6.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.9 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 10.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 5.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.2 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 2.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.2 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 2.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.3 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 6.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 1.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 7.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.7 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.1 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 1.1 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 11.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.5 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.6 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.8 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 2.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 8.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 3.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 3.2 GO:0020037 heme binding(GO:0020037)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 7.4 GO:0008289 lipid binding(GO:0008289)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.0 GO:0005542 folic acid binding(GO:0005542)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 2.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 8.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.7 PID P73PATHWAY p73 transcription factor network
0.1 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 5.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.9 PID MYC PATHWAY C-MYC pathway
0.1 3.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 4.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 1.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 6.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 3.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 4.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 1.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 0.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 3.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 1.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 5.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 4.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 2.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 7.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 9.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 4.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 4.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 0.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 2.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex