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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for cebpa

Z-value: 2.24

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Transcription factors associated with cebpa

Gene Symbol Gene ID Gene Info
ENSDARG00000036074 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpadr11_v1_chr7_-_38087865_380878650.196.5e-02Click!

Activity profile of cebpa motif

Sorted Z-values of cebpa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_50147948 65.68 ENSDART00000149010
haptoglobin
chr22_-_26236188 44.57 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
complement component c3b, tandem duplicate 1
chr5_-_63509581 43.76 ENSDART00000097325
complement component 5
chr1_+_59067978 39.81 ENSDART00000172613
si:ch1073-110a20.7
chr8_-_39739627 37.27 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr8_-_13972626 36.30 ENSDART00000144296
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr15_+_28202170 34.87 ENSDART00000077736
vitronectin a
chr14_+_21107032 34.64 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldolase b, fructose-bisphosphate
chr1_+_10051763 33.89 ENSDART00000011701
fibrinogen beta chain
chr9_-_32847642 33.02 ENSDART00000121506
hemopexin
chr22_-_26175237 32.00 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr14_+_21106444 31.80 ENSDART00000075744
ENSDART00000132363
aldolase b, fructose-bisphosphate
chr5_+_28830388 31.66 ENSDART00000149150
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr14_+_16345003 31.33 ENSDART00000003040
ENSDART00000165193
intelectin 3
chr13_-_20540790 30.97 ENSDART00000131467
si:ch1073-126c3.2
chr5_+_45677781 30.78 ENSDART00000163120
ENSDART00000126537
group-specific component (vitamin D binding protein)
chr1_-_10071422 30.01 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr11_+_37178271 29.26 ENSDART00000161771
inter-alpha-trypsin inhibitor heavy chain 3b
chr20_+_23440632 29.07 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr19_-_5699703 28.74 ENSDART00000082050
zgc:174904
chr6_+_22068589 26.41 ENSDART00000151205
aldehyde dehydrogenase 1 family, member L1
chr2_-_51794472 25.35 ENSDART00000186652

chr24_-_38094074 24.06 ENSDART00000140802
ENSDART00000137734
C-reactive protein 2
chr15_+_14856307 23.98 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr14_+_36885524 23.61 ENSDART00000032547
leukocyte cell-derived chemotaxin 2 like
chr2_-_32643738 22.84 ENSDART00000112452
si:dkeyp-73d8.9
chr3_+_19299309 22.70 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr5_-_20123002 22.64 ENSDART00000026516
peroxisomal membrane protein 2
chr16_+_23984179 22.54 ENSDART00000175879
apolipoprotein C-II
chr6_+_21202639 22.51 ENSDART00000083126
cell death-inducing DFFA-like effector c
chr23_+_45282858 21.02 ENSDART00000162353

chr9_-_9989660 20.44 ENSDART00000081463
UDP glucuronosyltransferase 1 family a, b
chr8_+_30699429 20.38 ENSDART00000005345
ureidopropionase, beta
chr23_+_17980875 20.15 ENSDART00000163452
chitinase, acidic.6
chr16_-_21785261 19.95 ENSDART00000078858
si:ch73-86n18.1
chr19_+_8606883 19.19 ENSDART00000054469
ENSDART00000185264
S100 calcium binding protein A10a
chr17_-_36529449 18.66 ENSDART00000187252
collectin sub-family member 11
chr16_+_50289916 18.35 ENSDART00000168861
ENSDART00000167332
hepcidin antimicrobial peptide
chr2_-_6039757 17.98 ENSDART00000013079
sterol carrier protein 2a
chr5_-_25723079 17.94 ENSDART00000014013
guanine deaminase
chr22_-_36875264 17.85 ENSDART00000137548
kininogen 1
chr21_-_40630650 17.71 ENSDART00000172706
phosphate cytidylyltransferase 1, choline, beta b
chr24_-_33284945 17.58 ENSDART00000155429
ENSDART00000112845
zgc:195173
chr21_+_38002879 17.42 ENSDART00000065183
claudin 2
chr25_-_32311048 17.05 ENSDART00000181806
ENSDART00000086334

chr9_+_38292947 16.98 ENSDART00000146663
transcription factor CP2-like 1
chr4_-_9549693 16.95 ENSDART00000160242

chr7_-_4296771 16.23 ENSDART00000128855
cerebellin 11
chr19_-_15192840 16.02 ENSDART00000151337
phosphatase and actin regulator 4a
chr7_-_60831082 15.62 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr24_-_2843107 14.59 ENSDART00000165290
cytochrome b5 type A (microsomal)
chr3_-_36750068 14.38 ENSDART00000173388
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr13_+_33688474 14.37 ENSDART00000161465

chr3_-_40955780 14.31 ENSDART00000130130
cytochrome P450, family 3, subfamily c, polypeptide 3
chr5_+_26795773 14.23 ENSDART00000145631
transcobalamin II
chr3_-_40275096 14.11 ENSDART00000141578
serine hydroxymethyltransferase 1 (soluble)
chr2_-_20120904 13.82 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr23_+_42454292 13.29 ENSDART00000171459
y cytochrome P450, family 2, subfamily AA, polypeptide 2
chr9_-_48736388 13.17 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr7_+_56577522 12.90 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr11_-_23459779 12.47 ENSDART00000183935
ENSDART00000184125
ENSDART00000193284
pleckstrin homology domain containing, family A member 6
chr9_+_41080029 12.40 ENSDART00000141179
ENSDART00000019289
zgc:136439
chr2_-_40199780 12.19 ENSDART00000113901
chemokine (C-C motif) ligand 34a, duplicate 4
chr2_-_127945 12.03 ENSDART00000056453
insulin-like growth factor binding protein 1b
chr15_-_29348212 11.98 ENSDART00000133117
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr1_-_59139599 11.96 ENSDART00000152233
si:ch1073-110a20.3
chr24_-_36727922 11.86 ENSDART00000135142
si:ch73-334d15.1
chr4_-_12725513 11.84 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr7_-_46019756 11.80 ENSDART00000162583
zgc:162297
chr12_+_48390715 11.77 ENSDART00000149351
stearoyl-CoA desaturase (delta-9-desaturase)
chr5_+_9360394 11.41 ENSDART00000124642

chr25_+_31323978 11.38 ENSDART00000067030
lymphocyte-specific protein 1
chr18_-_38216584 11.29 ENSDART00000144622
si:dkey-10o6.2
chr22_-_17595310 11.23 ENSDART00000099056
glutathione peroxidase 4a
chr12_-_17199381 11.22 ENSDART00000193292
lipase, gastric
chr24_-_32582378 11.03 ENSDART00000066590
retinol dehydrogenase 12, like
chr10_-_22803740 11.01 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr16_-_4640539 10.80 ENSDART00000076955
ENSDART00000131949
cytochrome P450, family 4, subfamily T, polypeptide 8
chr17_-_6076266 10.68 ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr19_-_40192249 10.64 ENSDART00000051972
granulin 1
chr5_+_4332220 10.54 ENSDART00000051699
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr7_-_10560964 10.44 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr25_+_13191615 10.41 ENSDART00000168849
si:ch211-147m6.2
chr21_+_20901505 10.02 ENSDART00000132741
complement component 7b
chr10_+_8401929 9.58 ENSDART00000059028
hydrogen voltage-gated channel 1
chr1_-_56032619 9.57 ENSDART00000143793
complement component c3a, duplicate 4
chr14_+_15155684 9.56 ENSDART00000167966
zgc:158852
chr17_-_6519423 9.36 ENSDART00000175626

chr21_-_42831033 9.36 ENSDART00000160998
serine/threonine kinase 10
chr19_-_41213718 9.20 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr19_+_5674907 8.95 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr24_-_32582880 8.81 ENSDART00000186307
retinol dehydrogenase 12, like
chr1_+_24376394 8.77 ENSDART00000102542
zgc:171517
chr8_+_39802506 8.75 ENSDART00000018862
HNF1 homeobox a
chr2_-_51634431 8.65 ENSDART00000165568
polymeric immunoglobulin receptor
chr19_-_40191358 8.57 ENSDART00000183919
granulin 1
chr23_-_36441693 8.50 ENSDART00000024354
cysteine sulfinic acid decarboxylase
chr8_-_26961779 8.43 ENSDART00000099214
solute carrier family 16 (monocarboxylate transporter), member 1b
chr6_-_43449013 8.39 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr15_-_1885247 8.26 ENSDART00000149703
P450 (cytochrome) oxidoreductase b
chr4_-_12723585 8.09 ENSDART00000185639
microsomal glutathione S-transferase 1.2
chr1_-_52222989 7.87 ENSDART00000010236
calponin 1, basic, smooth muscle, a
chr17_-_6076084 7.68 ENSDART00000058890
epoxide hydrolase 2, cytoplasmic
chr21_-_39058490 7.64 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr9_-_21838045 7.62 ENSDART00000147471
aconitate decarboxylase 1
chr20_+_25563105 7.49 ENSDART00000063100
cytochrome P450, family 2, subfamily P, polypeptide 6
chr4_+_14957360 7.29 ENSDART00000002770
ENSDART00000111882
ENSDART00000148292
tetraspanin 33a
chr1_+_59090583 7.28 ENSDART00000150658
microfibril associated protein 4
chr18_-_25276932 7.25 ENSDART00000076183
perilipin 1
chr14_+_32918172 7.16 ENSDART00000182867
ligand of numb-protein X 2b
chr3_-_29925482 7.13 ENSDART00000151525
granulin a
chr3_-_18805225 7.08 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr10_-_36808348 7.06 ENSDART00000099320
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr9_-_53062083 7.02 ENSDART00000122155
zmp:0000000936
chr23_+_42292748 6.91 ENSDART00000166113
ENSDART00000158684
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr1_+_59090743 6.87 ENSDART00000100199
microfibril associated protein 4
chr13_-_24257631 6.85 ENSDART00000146524
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr8_-_41228530 6.64 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr9_-_27398369 6.58 ENSDART00000186499
testis expressed 30
chr21_-_22715297 6.54 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr6_+_8314451 6.50 ENSDART00000147793
ENSDART00000183688
glutaryl-CoA dehydrogenase a
chr24_-_17049270 6.45 ENSDART00000175508
methionine sulfoxide reductase B2
chr11_+_18183220 6.41 ENSDART00000113468

chr1_+_17892944 6.26 ENSDART00000013021
toll-like receptor 3
chr10_+_39212898 6.12 ENSDART00000159501
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr7_-_30932094 6.05 ENSDART00000057677
telomere repeat binding bouquet formation protein 2
chr5_-_56412262 6.05 ENSDART00000083079
acetyl-CoA carboxylase alpha
chr10_+_39212601 6.04 ENSDART00000168778
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr24_-_26485098 6.03 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr7_+_37359004 5.98 ENSDART00000192134
ENSDART00000189239
spalt-like transcription factor 1a
chr7_+_42935126 5.97 ENSDART00000157747

chr16_+_16977786 5.95 ENSDART00000043173
ENSDART00000132150
ribosomal protein L18
chr11_+_3959495 5.74 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_-_18585046 5.71 ENSDART00000147228
family with sequence similarity 114, member A1
chr10_-_29733194 5.70 ENSDART00000149252
si:ch73-261i21.2
chr23_-_19153378 5.70 ENSDART00000019045
ENSDART00000183681
emopamil binding protein (sterol isomerase)
chr2_+_17055069 5.68 ENSDART00000115078
thrombopoietin
chr15_-_28618502 5.64 ENSDART00000086902
solute carrier family 6 (neurotransmitter transporter), member 4a
chr9_+_29520696 5.63 ENSDART00000144430
ferredoxin 1
chr16_-_38333976 5.59 ENSDART00000031895
CDC42 small effector 1
chr13_+_7387822 5.54 ENSDART00000148240
exocyst complex component 3-like 4
chr9_+_907459 5.53 ENSDART00000034850
ENSDART00000144114
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr11_+_41936435 5.46 ENSDART00000173103
aldehyde dehydrogenase 4 family, member A1
chr7_+_15736230 5.44 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr25_-_13320986 5.43 ENSDART00000169238
si:ch211-194m7.8
chr20_+_2039518 5.41 ENSDART00000043157

chr23_-_31633201 5.36 ENSDART00000143335
ENSDART00000053531
solute carrier family 2 (facilitated glucose transporter), member 12
chr20_-_33961697 5.33 ENSDART00000061765
selectin P
chr3_+_49097775 5.31 ENSDART00000169185
zgc:123284
chr1_+_9954489 5.24 ENSDART00000005895
ENSDART00000183003
protein disulfide isomerase family A, member 2
chr12_+_31616412 5.21 ENSDART00000124439
carboxypeptidase N, polypeptide 1
chr12_+_47081783 5.15 ENSDART00000158568
5-methyltetrahydrofolate-homocysteine methyltransferase
chr22_-_20695237 5.12 ENSDART00000112722
oogenesis-related gene
chr6_+_8315050 5.10 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr6_+_42475730 5.06 ENSDART00000150226
macrophage stimulating 1 receptor a
chr20_+_32118559 5.04 ENSDART00000026273
CD164 molecule, sialomucin
chr17_+_10318071 5.01 ENSDART00000161844
forkhead box A1
chr17_-_51938663 4.86 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr17_+_43659940 4.85 ENSDART00000145738
ENSDART00000075619
2-aminoethanethiol (cysteamine) dioxygenase b
chr12_+_6002715 4.77 ENSDART00000114961
si:ch211-131k2.3
chr3_-_29870848 4.64 ENSDART00000186457
ribosomal protein L3
chr20_-_40729364 4.63 ENSDART00000101014
connexin 32.2
chr24_-_26369185 4.62 ENSDART00000080039
leucine rich repeat containing 31
chr10_+_4924388 4.60 ENSDART00000108595
solute carrier family 46 member 2
chr23_-_26128593 4.60 ENSDART00000136855
ENSDART00000193700
ENSDART00000163984
regulator of complement activation group 2 gene 2
chr1_-_57629639 4.59 ENSDART00000158984
zmp:0000001289
chr23_+_27675581 4.59 ENSDART00000127198
ribosomal protein S26
chr4_-_287425 4.59 ENSDART00000159128
enoyl CoA hydratase domain containing 3
chr22_-_17677947 4.56 ENSDART00000139911
tight junction protein 3
chr10_-_23099809 4.46 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
notchless homolog 1 (Drosophila)
chr24_+_2843268 4.44 ENSDART00000170529
si:ch211-152c8.2
chr4_-_16658514 4.44 ENSDART00000133837
DENN/MADD domain containing 5B
chr10_+_9553935 4.41 ENSDART00000028855
si:ch211-243g18.2
chr4_+_21866851 4.39 ENSDART00000177640
acyl-CoA synthetase short chain family member 3
chr23_+_9220436 4.37 ENSDART00000033663
ENSDART00000139870
ribosomal protein S21
chr9_-_46395240 4.36 ENSDART00000169044
si:dkey-79p17.3
chr21_-_41065369 4.33 ENSDART00000143749
leucyl-tRNA synthetase b
chr14_+_3507326 4.29 ENSDART00000159326
glutathione S-transferase pi 1
chr6_-_16456093 4.29 ENSDART00000083305
ENSDART00000181640
solute carrier family 19 (thiamine transporter), member 2
chr3_+_3573696 4.27 ENSDART00000169680

chr14_-_46238186 4.27 ENSDART00000173245
si:ch211-113d11.6
chr12_+_46960579 4.24 ENSDART00000149032
ornithine aminotransferase
chr23_-_7674902 4.19 ENSDART00000185612
ENSDART00000180524
pleiomorphic adenoma gene-like 2
chr16_+_44906324 4.17 ENSDART00000074960
cd22 molecule
chr20_-_36679233 4.09 ENSDART00000062908
ribosomal protein L7-like 1
chr18_-_16792561 4.06 ENSDART00000145546
adenosine monophosphate deaminase 3b
chr23_+_38957738 4.05 ENSDART00000193480
ATPase phospholipid transporting 9A (putative)
chr2_+_11685742 4.03 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr19_+_4463389 4.02 ENSDART00000168805
potassium channel, subfamily K, member 9
chr7_+_12950507 3.95 ENSDART00000067629
ENSDART00000158004
serum amyloid A
chr25_+_19238175 3.90 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
diphosphoinositol pentakisphosphate kinase 1b
chr2_-_17115256 3.87 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr12_-_45304971 3.87 ENSDART00000186537
ENSDART00000126405
ferredoxin reductase
chr3_+_43955864 3.85 ENSDART00000168267

chr8_+_17869225 3.85 ENSDART00000080079
solute carrier family 44, member 5b
chr1_+_52563298 3.80 ENSDART00000142465
ATP-binding cassette, sub-family A (ABC1), member 1A
chr12_+_25775734 3.78 ENSDART00000024415
ENSDART00000149198
endothelial PAS domain protein 1a
chr5_+_30520249 3.76 ENSDART00000013431
hydroxymethylbilane synthase a
chr24_-_7583461 3.74 ENSDART00000171568
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr17_-_40110782 3.74 ENSDART00000126929
si:dkey-187k19.2

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 36.3 GO:2000257 regulation of protein activation cascade(GO:2000257)
8.8 26.4 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
6.8 34.2 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
6.8 40.7 GO:0032367 intracellular cholesterol transport(GO:0032367)
6.0 17.9 GO:0006145 purine nucleobase catabolic process(GO:0006145)
4.7 14.2 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
4.7 23.7 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
4.7 14.1 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
4.6 63.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
3.1 50.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
3.0 12.0 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
2.9 11.8 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
2.8 66.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.6 10.5 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
2.6 18.3 GO:0032570 response to progesterone(GO:0032570)
2.6 17.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
2.4 7.2 GO:0002526 acute inflammatory response(GO:0002526)
2.3 16.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.1 6.3 GO:0032602 chemokine production(GO:0032602) toll-like receptor 3 signaling pathway(GO:0034138)
2.0 6.1 GO:0044821 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
1.9 14.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.8 20.2 GO:0006032 chitin catabolic process(GO:0006032)
1.7 6.8 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
1.6 8.2 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
1.6 6.4 GO:0030091 protein repair(GO:0030091)
1.5 10.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
1.4 5.6 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
1.4 9.6 GO:0071294 cellular response to zinc ion(GO:0071294)
1.3 35.1 GO:0051180 vitamin transport(GO:0051180)
1.2 22.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
1.2 17.6 GO:0050994 regulation of lipid catabolic process(GO:0050994)
1.1 8.8 GO:0042559 tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559) tetrahydrobiopterin metabolic process(GO:0046146)
1.1 12.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.1 5.5 GO:0006562 proline catabolic process(GO:0006562)
1.1 7.6 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
1.1 20.2 GO:0042574 retinal metabolic process(GO:0042574)
1.1 3.2 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
1.0 6.3 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.0 15.6 GO:0046686 response to cadmium ion(GO:0046686)
1.0 3.8 GO:0032371 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.9 10.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.9 7.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.9 5.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.9 6.0 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.7 2.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.7 18.4 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.7 7.3 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.7 5.6 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.7 12.7 GO:0043687 post-translational protein modification(GO:0043687)
0.7 3.3 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.6 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.6 3.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.6 2.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.6 7.3 GO:0051604 protein maturation(GO:0051604)
0.6 2.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.6 5.5 GO:0051601 exocyst localization(GO:0051601)
0.6 1.7 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.5 27.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.5 7.4 GO:0032264 IMP salvage(GO:0032264)
0.5 9.4 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.5 3.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.5 5.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.5 3.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.5 4.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.5 2.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.5 2.8 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.5 1.8 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 4.6 GO:0030104 water homeostasis(GO:0030104)
0.4 4.0 GO:0006465 signal peptide processing(GO:0006465)
0.4 1.3 GO:0090189 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4 3.4 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.4 0.8 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.4 3.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.4 2.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 2.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 18.1 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.4 1.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.4 2.0 GO:0006833 water transport(GO:0006833)
0.4 6.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4 2.7 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.4 31.2 GO:0072376 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.4 9.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.4 1.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.4 1.5 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.4 1.1 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.4 2.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 18.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.3 2.8 GO:0046323 glucose import(GO:0046323)
0.3 5.2 GO:0042558 pteridine-containing compound metabolic process(GO:0042558)
0.3 19.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.3 1.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 6.7 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.3 2.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 3.6 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3 3.9 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.3 2.5 GO:0030325 adrenal gland development(GO:0030325)
0.3 4.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 8.7 GO:0003323 type B pancreatic cell development(GO:0003323)
0.3 3.9 GO:0006020 inositol metabolic process(GO:0006020)
0.3 5.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.3 2.5 GO:0006517 protein deglycosylation(GO:0006517)
0.3 7.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.3 4.2 GO:0036065 fucosylation(GO:0036065)
0.3 1.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 4.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 3.0 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 5.7 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.2 15.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 1.4 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.2 2.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2 2.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 9.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.2 4.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 3.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 4.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.7 GO:1901998 toxin transport(GO:1901998)
0.2 0.6 GO:0072388 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.2 2.9 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 1.9 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.2 2.0 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 1.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.2 3.1 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 1.5 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.6 GO:0003151 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.1 1.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 2.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 12.1 GO:0001666 response to hypoxia(GO:0001666)
0.1 3.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.4 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 2.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 2.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 5.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 1.6 GO:0008354 germ cell migration(GO:0008354)
0.1 8.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 4.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 3.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 4.8 GO:0003014 renal system process(GO:0003014)
0.1 2.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 12.1 GO:0009617 response to bacterium(GO:0009617)
0.1 1.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.4 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 3.4 GO:0009062 fatty acid catabolic process(GO:0009062)
0.1 2.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 2.2 GO:0021983 pituitary gland development(GO:0021983)
0.1 43.9 GO:0006955 immune response(GO:0006955)
0.1 0.8 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.5 GO:0042311 vasodilation(GO:0042311)
0.1 9.0 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 6.2 GO:0006979 response to oxidative stress(GO:0006979)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.4 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.4 GO:0015809 arginine transport(GO:0015809)
0.1 0.9 GO:0060021 palate development(GO:0060021)
0.1 1.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737) DNA catabolic process(GO:0006308)
0.1 0.3 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 1.6 GO:0051607 defense response to virus(GO:0051607)
0.1 1.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 6.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.9 GO:0032438 melanosome organization(GO:0032438)
0.0 0.5 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:1901741 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) positive regulation of myoblast fusion(GO:1901741)
0.0 1.3 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 3.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 2.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.9 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.7 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 34.1 GO:0006508 proteolysis(GO:0006508)
0.0 18.9 GO:0042981 regulation of apoptotic process(GO:0042981)
0.0 4.9 GO:0009725 response to hormone(GO:0009725)
0.0 1.1 GO:0036269 swimming behavior(GO:0036269)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 3.9 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 2.5 GO:0044272 sulfur compound biosynthetic process(GO:0044272)
0.0 0.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.7 GO:0001707 mesoderm formation(GO:0001707)
0.0 1.4 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
21.3 63.9 GO:0005577 fibrinogen complex(GO:0005577)
2.3 22.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.0 4.0 GO:0005787 signal peptidase complex(GO:0005787)
0.9 2.7 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.6 10.0 GO:0005579 membrane attack complex(GO:0005579)
0.6 2.3 GO:0097268 cytoophidium(GO:0097268)
0.5 4.4 GO:0042788 polysomal ribosome(GO:0042788)
0.5 1.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.5 1.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.4 1.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.4 48.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 1.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 3.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.3 427.2 GO:0005615 extracellular space(GO:0005615)
0.3 1.6 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 5.1 GO:0009925 basal plasma membrane(GO:0009925)
0.2 14.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 0.7 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.2 1.2 GO:0032797 SMN complex(GO:0032797)
0.2 5.5 GO:0000145 exocyst(GO:0000145)
0.2 125.8 GO:0005576 extracellular region(GO:0005576)
0.2 29.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 3.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.2 6.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 16.0 GO:0030027 lamellipodium(GO:0030027)
0.1 1.0 GO:0036156 inner dynein arm(GO:0036156)
0.1 7.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 7.3 GO:0005811 lipid particle(GO:0005811)
0.1 14.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 110.1 GO:0005739 mitochondrion(GO:0005739)
0.1 46.8 GO:0005815 microtubule organizing center(GO:0005815)
0.1 4.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 5.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 6.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 4.0 GO:0005643 nuclear pore(GO:0005643)
0.1 0.6 GO:0070938 contractile ring(GO:0070938)
0.1 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 2.6 GO:0008305 integrin complex(GO:0008305)
0.1 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 3.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 4.4 GO:0005882 intermediate filament(GO:0005882)
0.0 3.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0005840 ribosome(GO:0005840)
0.0 1.2 GO:0001726 ruffle(GO:0001726)
0.0 1.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 1.9 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 18.4 GO:0005829 cytosol(GO:0005829)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 3.0 GO:0030425 dendrite(GO:0030425)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 30.8 GO:0005499 vitamin D binding(GO:0005499)
8.8 26.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
8.3 66.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
6.2 18.7 GO:0042806 fucose binding(GO:0042806)
6.1 18.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
5.7 22.7 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
5.2 15.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
4.7 14.1 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
4.6 18.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
3.5 17.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
3.4 13.5 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
3.0 12.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.9 11.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
2.9 11.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
2.8 13.8 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
2.4 19.4 GO:0031419 cobalamin binding(GO:0031419)
2.3 18.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
2.2 8.8 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
2.1 8.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
1.9 5.6 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
1.9 9.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.8 20.2 GO:0004568 chitinase activity(GO:0004568)
1.7 6.8 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
1.6 13.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.6 6.5 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.6 33.1 GO:0070492 oligosaccharide binding(GO:0070492)
1.5 6.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.5 10.5 GO:0019809 spermidine binding(GO:0019809)
1.4 7.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
1.4 37.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.3 18.0 GO:0016408 C-acyltransferase activity(GO:0016408)
1.2 205.1 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
1.1 12.0 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
1.0 3.9 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.9 8.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.8 2.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.8 5.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.8 3.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.8 7.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.8 3.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.8 15.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.7 7.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 8.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 19.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.7 7.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 3.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.6 3.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.6 3.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.6 21.2 GO:0019239 deaminase activity(GO:0019239)
0.6 1.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.6 20.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.6 2.3 GO:0003883 CTP synthase activity(GO:0003883)
0.6 32.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.5 4.3 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.5 1.6 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.5 36.8 GO:0003823 antigen binding(GO:0003823)
0.5 42.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 2.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.5 2.3 GO:0015037 glutathione-disulfide reductase activity(GO:0004362) peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.4 3.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.4 11.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 3.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.4 5.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 5.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 21.6 GO:0015485 cholesterol binding(GO:0015485)
0.4 18.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.4 1.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.4 1.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 4.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.4 15.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 1.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.3 3.0 GO:0008494 translation activator activity(GO:0008494)
0.3 4.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 6.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 6.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 18.2 GO:0009055 electron carrier activity(GO:0009055)
0.3 2.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 64.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 2.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.3 1.3 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.3 5.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.2 1.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 0.7 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.2 1.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 2.0 GO:0015250 water channel activity(GO:0015250)
0.2 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 2.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 2.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 4.9 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.2 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.6 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.2 2.9 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 1.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 8.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 0.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 1.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 0.8 GO:0015288 porin activity(GO:0015288)
0.2 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 4.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.7 GO:0005112 Notch binding(GO:0005112)
0.1 2.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 11.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 1.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 24.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 20.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 10.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.5 GO:0008483 transaminase activity(GO:0008483)
0.1 0.4 GO:0070224 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 1.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 4.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 11.4 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 2.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 10.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.1 1.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 3.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 16.7 GO:0030246 carbohydrate binding(GO:0030246)
0.1 8.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 1.9 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.7 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 4.3 GO:0051213 dioxygenase activity(GO:0051213)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.6 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 2.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 4.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 2.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 5.6 GO:0005125 cytokine activity(GO:0005125)
0.0 31.1 GO:0005102 receptor binding(GO:0005102)
0.0 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 3.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0050661 NADP binding(GO:0050661)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.4 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 2.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 81.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.8 80.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.8 11.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.7 58.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 66.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 19.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 3.3 ST STAT3 PATHWAY STAT3 Pathway
0.3 6.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 15.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 5.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 4.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 63.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
4.2 54.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
3.6 17.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
3.2 66.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
2.9 20.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
2.3 22.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.9 50.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.1 29.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.8 4.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.8 7.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.8 5.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.7 6.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.7 2.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 7.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6 6.0 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.6 34.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.6 5.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.5 8.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 9.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.4 4.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 3.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 3.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 14.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 2.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 3.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 3.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 3.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 5.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 2.3 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.2 6.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 2.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 5.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 5.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 2.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 9.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 14.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 5.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.0 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 3.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 5.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins