ISMARA results: cebpg

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for cebpg

Z-value: 1.58

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Transcription factors associated with cebpg

Gene Symbol	Gene ID	Gene Info
cebpg NCBI UniProt	ENSDARG00000036073	CCAAT enhancer binding protein gamma

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
cebpg	dr11_v1_chr7_+_38090515_38090515	0.16	1.3e-01	Click!

Activity profile of cebpg motif

Sorted Z-values of cebpg motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_10071422 Show fit	49.43	ENSDART00000135522 ENSDART00000033118	fga NCBI UniProt Show fit	fibrinogen alpha chain
chr22_-_23668356 Show fit	43.81	ENSDART00000167106 ENSDART00000159622 ENSDART00000163228	cfh NCBI UniProt Show fit	complement factor H
chr5_-_63509581 Show fit	33.58	ENSDART00000097325	c5 NCBI UniProt Show fit	complement component 5
chr20_-_40755614 Show fit	32.21	ENSDART00000061247	cx32.3 NCBI UniProt Show fit	connexin 32.3
chr22_-_26175237 Show fit	30.77	ENSDART00000108737	c3b.2 NCBI UniProt Show fit	complement component c3b, tandem duplicate 2
chr8_-_50147948 Show fit	29.77	ENSDART00000149010	hp NCBI UniProt Show fit	haptoglobin
chr5_+_45677781 Show fit	26.40	ENSDART00000163120 ENSDART00000126537	gc NCBI UniProt Show fit	group-specific component (vitamin D binding protein)
chr22_-_26236188 Show fit	26.29	ENSDART00000162640 ENSDART00000167169 ENSDART00000138595	c3b.1 NCBI UniProt Show fit	complement component c3b, tandem duplicate 1
chr12_-_22524388 Show fit	21.36	ENSDART00000020942	shbg NCBI UniProt Show fit	sex hormone-binding globulin
chr22_-_24757785 Show fit	21.08	ENSDART00000078225	vtg5 NCBI UniProt Show fit	vitellogenin 5

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpg

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.3	49.4	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	38.8	GO:0006508	proteolysis(GO:0006508)
0.9	26.4	GO:0051180	vitamin transport(GO:0051180)
0.5	21.1	GO:0032355	response to estradiol(GO:0032355)
0.1	20.7	GO:0002040	sprouting angiogenesis(GO:0002040)
1.1	20.5	GO:0050994	regulation of lipid catabolic process(GO:0050994)
0.9	16.7	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
3.6	14.4	GO:0003418	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
1.1	14.2	GO:2000377	regulation of reactive oxygen species metabolic process(GO:2000377)
2.0	13.8	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)

Showing 1 to 10 of 102 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	224.3	GO:0005615	extracellular space(GO:0005615)
16.5	49.4	GO:0005577	fibrinogen complex(GO:0005577)
0.0	32.0	GO:0005576	extracellular region(GO:0005576)
1.7	16.7	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	12.6	GO:0005783	endoplasmic reticulum(GO:0005783)
0.1	11.5	GO:0030027	lamellipodium(GO:0030027)
1.4	10.9	GO:0001772	immunological synapse(GO:0001772)
0.4	9.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.2	8.8	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	8.1	GO:0005667	transcription factor complex(GO:0005667)

Showing 1 to 10 of 45 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	104.6	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	54.4	GO:0005102	receptor binding(GO:0005102)
0.2	46.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
3.1	31.0	GO:0016936	galactoside binding(GO:0016936)
8.8	26.4	GO:0005499	vitamin D binding(GO:0005499)
0.3	21.4	GO:0042562	hormone binding(GO:0042562)
3.0	21.1	GO:0045735	nutrient reservoir activity(GO:0045735)
0.3	15.8	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	14.9	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3	13.3	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)

Showing 1 to 10 of 88 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.9	49.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.6	21.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	15.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.5	10.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	9.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.2	9.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.3	6.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	2.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	2.6	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	2.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes

Showing 1 to 10 of 17 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
4.5	49.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
11.0	43.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.5	33.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.9	26.4	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
1.7	16.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
1.2	10.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	9.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.2	7.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	7.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4	6.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle

Showing 1 to 10 of 32 entries

Results for cebpg

Z-value: 1.58

Motif logo

Transcription factors associated with cebpg

Activity-expression correlation:

Activity profile of cebpg motif

Sorted Z-values of cebpg motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpg

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: