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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for crx+otx1

Z-value: 0.74

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Transcription factors associated with crx+otx1

Gene Symbol Gene ID Gene Info
crx
ENSDARG00000011989 cone-rod homeobox
otx1
ENSDARG00000094992 orthodenticle homeobox 1
crx
ENSDARG00000113850 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx1dr11_v1_chr17_+_24318753_243187530.672.4e-13Click!
crxdr11_v1_chr5_+_36932718_369327180.251.6e-02Click!

Activity profile of crx+otx1 motif

Sorted Z-values of crx+otx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_38079261 7.05 ENSDART00000105662
crp1
C-reactive protein 1
chr19_-_5207361 6.80 ENSDART00000174611
stx1b
syntaxin 1B
chr24_-_21689146 6.04 ENSDART00000105917
urad
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr21_+_13366353 5.54 ENSDART00000151630
si:ch73-62l21.1
si:ch73-62l21.1
chr25_+_21324588 5.52 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr3_+_62000822 5.51 ENSDART00000106680
rai1
retinoic acid induced 1
chr11_-_3366782 4.83 ENSDART00000127982
suox
sulfite oxidase
chr3_-_13068189 4.62 ENSDART00000167180
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr10_+_6013076 4.51 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr13_+_733027 4.38 ENSDART00000149547
nrxn1b
neurexin 1b
chr19_+_14921000 4.35 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr9_-_38042823 4.09 ENSDART00000141998
ENSDART00000133998
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr10_+_17026870 4.04 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr11_-_37693019 3.82 ENSDART00000102898
zgc:158258
zgc:158258
chr8_-_46572298 3.64 ENSDART00000030470
sult1st3
sulfotransferase family 1, cytosolic sulfotransferase 3
chr16_+_43219363 3.63 ENSDART00000183610
adam22
ADAM metallopeptidase domain 22
chr16_-_46579936 3.57 ENSDART00000166143
ENSDART00000127212
si:dkey-152b24.6
si:dkey-152b24.6
chr2_+_20430366 3.42 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr24_-_31140356 3.34 ENSDART00000167837
tmem56a
transmembrane protein 56a
chr4_+_72797711 3.30 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like
chr18_+_27439680 3.28 ENSDART00000014726
tp53i11b
tumor protein p53 inducible protein 11b
chr25_-_19090479 3.15 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr21_-_28340977 3.11 ENSDART00000141629
nrxn2a
neurexin 2a
chr22_+_17203752 3.05 ENSDART00000143376
rab3b
RAB3B, member RAS oncogene family
chr6_-_58757131 2.93 ENSDART00000083582
soat2
sterol O-acyltransferase 2
chr13_-_29406534 2.85 ENSDART00000100877
zgc:153142
zgc:153142
chr23_+_2560005 2.83 ENSDART00000186906
GGT7
gamma-glutamyltransferase 7
chr10_-_42898220 2.72 ENSDART00000099270
CU326366.2

chr8_-_4618653 2.70 ENSDART00000025535
sept5a
septin 5a
chr20_-_10120442 2.68 ENSDART00000144970
meis2b
Meis homeobox 2b
chr10_+_40235959 2.66 ENSDART00000145862
gramd1ba
GRAM domain containing 1Ba
chr14_-_4273396 2.50 ENSDART00000127318
frmpd1b
FERM and PDZ domain containing 1b
chr6_-_10168822 2.38 ENSDART00000151016
b3galt1a
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1a
chr2_-_39036604 2.36 ENSDART00000129963
rbp1
retinol binding protein 1b, cellular
chr21_-_24632778 2.32 ENSDART00000132533
ENSDART00000058370
arhgap32b
Rho GTPase activating protein 32b
chr1_+_35949269 2.26 ENSDART00000180628
BX276105.3

chr17_-_7371564 2.25 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr15_+_46605482 2.24 ENSDART00000184449
CABZ01044048.1

chr22_+_25453334 2.21 ENSDART00000123962
si:ch211-12h2.6
si:ch211-12h2.6
chr16_+_9726038 2.19 ENSDART00000192988
ENSDART00000020859
pip5k1ab
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr3_+_15296824 2.15 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr7_+_67486807 2.12 ENSDART00000159989
cpne7
copine VII
chr23_+_7710721 2.09 ENSDART00000186852
ENSDART00000161193
kif3b
kinesin family member 3B
chr13_-_40499296 2.08 ENSDART00000158338
CNNM1
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr11_-_1550709 2.08 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr13_-_30161684 2.07 ENSDART00000040409
ppa1b
pyrophosphatase (inorganic) 1b
chr21_-_39058490 2.03 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr21_+_33503835 2.00 ENSDART00000125658
clint1b
clathrin interactor 1b
chr20_+_13969414 1.98 ENSDART00000049864
rd3
retinal degeneration 3
chr21_+_31838386 1.97 ENSDART00000135591
si:ch211-12m10.1
si:ch211-12m10.1
chr2_+_44972720 1.94 ENSDART00000075146
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr5_-_27993972 1.90 ENSDART00000175819
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr19_+_45970692 1.87 ENSDART00000158781
si:ch211-153f2.7
si:ch211-153f2.7
chr19_-_32641725 1.82 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr6_-_16406210 1.77 ENSDART00000012023
faimb
Fas apoptotic inhibitory molecule b
chr5_+_66355153 1.76 ENSDART00000082745
si:ch211-261c8.5
si:ch211-261c8.5
chr23_+_45512825 1.76 ENSDART00000064846
prelid1b
PRELI domain containing 1b
chr20_-_54014373 1.73 ENSDART00000152934
si:dkey-241l7.6
si:dkey-241l7.6
chr9_+_21151138 1.72 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr4_+_11053301 1.70 ENSDART00000140362
ccdc59
coiled-coil domain containing 59
chr18_-_8579907 1.70 ENSDART00000147284
FRMD4A
si:ch211-220f12.1
chr25_-_204019 1.70 ENSDART00000188440
ENSDART00000191735
FP236318.2

chr11_+_19080400 1.69 ENSDART00000044423
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr2_-_42864472 1.69 ENSDART00000134139
adcy8
adenylate cyclase 8 (brain)
chr10_-_40968095 1.66 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr25_+_35913614 1.66 ENSDART00000022437
gpia
glucose-6-phosphate isomerase a
chr13_+_15581270 1.63 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr2_-_32387441 1.63 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr20_-_54014539 1.62 ENSDART00000060466
si:dkey-241l7.6
si:dkey-241l7.6
chr14_+_52413846 1.60 ENSDART00000160952
noa1
nitric oxide associated 1
chr2_-_15349382 1.58 ENSDART00000057238
olfm3b
olfactomedin 3b
chr20_-_20932760 1.54 ENSDART00000152415
ENSDART00000039907
btbd6b
BTB (POZ) domain containing 6b
chr4_+_12111154 1.54 ENSDART00000036779
tmem178b
transmembrane protein 178B
chr9_+_17982737 1.53 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr9_+_10014817 1.52 ENSDART00000132065
nxph2a
neurexophilin 2a
chr16_-_16701718 1.48 ENSDART00000143550
si:dkey-8k3.2
si:dkey-8k3.2
chr2_+_33052169 1.46 ENSDART00000180008
rnf220a
ring finger protein 220a
chr7_+_39011355 1.45 ENSDART00000173855
dgkza
diacylglycerol kinase, zeta a
chr18_-_10713414 1.42 ENSDART00000034817
rbm28
RNA binding motif protein 28
chr3_-_15679107 1.40 ENSDART00000080441
zgc:66443
zgc:66443
chr3_-_20058417 1.37 ENSDART00000165695
ubtf
upstream binding transcription factor, RNA polymerase I
chr2_-_31686353 1.36 ENSDART00000126177
ENSDART00000056679
e2f5
E2F transcription factor 5
chr25_+_18964782 1.34 ENSDART00000017299
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr3_+_32842825 1.34 ENSDART00000122228
prr14
proline rich 14
chr23_+_16935494 1.32 ENSDART00000143120
si:dkey-147f3.4
si:dkey-147f3.4
chr3_-_12903609 1.31 ENSDART00000160522
ccdc137
coiled-coil domain containing 137
chr19_+_43884120 1.30 ENSDART00000139684
ENSDART00000142312
lypla2
lysophospholipase II
chr14_-_25985698 1.30 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr16_+_38159758 1.29 ENSDART00000058666
ENSDART00000112165
pi4kb
phosphatidylinositol 4-kinase, catalytic, beta
chr14_-_8816933 1.28 ENSDART00000163383
si:dkeyp-115e12.7
si:dkeyp-115e12.7
chr5_-_27994679 1.25 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr4_+_5196469 1.23 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr10_+_39476432 1.23 ENSDART00000190375
ENSDART00000183954
kirrel3a
kirre like nephrin family adhesion molecule 3a
chr10_-_25852517 1.22 ENSDART00000191551
trpc4a
transient receptor potential cation channel, subfamily C, member 4a
chr2_+_49417900 1.21 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr22_-_16154771 1.20 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr16_+_4055331 1.19 ENSDART00000128978
CR391998.1

chr1_-_17650223 1.18 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr3_-_15210491 1.17 ENSDART00000037906
hirip3
HIRA interacting protein 3
chr17_+_18031899 1.15 ENSDART00000022758
setd3
SET domain containing 3
chr21_+_36581384 1.14 ENSDART00000183924
BX936439.1

chr17_+_2130018 1.14 ENSDART00000193675
ENSDART00000110529
bub1bb
BUB1 mitotic checkpoint serine/threonine kinase Bb
chr14_+_11909966 1.14 ENSDART00000171829
frmpd3
FERM and PDZ domain containing 3
chr17_+_14886828 1.12 ENSDART00000010507
ENSDART00000131052
ptger2a
prostaglandin E receptor 2a (subtype EP2)
chr12_-_35883814 1.12 ENSDART00000177986
ENSDART00000129888
cep131
centrosomal protein 131
chr2_+_24722771 1.12 ENSDART00000147207
pik3r2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr25_+_32031536 1.12 ENSDART00000173656
tjp1b
tight junction protein 1b
chr19_-_3106447 1.12 ENSDART00000137987
si:ch211-80h18.1
si:ch211-80h18.1
chr13_+_41917606 1.09 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr2_-_32551178 1.09 ENSDART00000145603
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr7_+_39011852 1.08 ENSDART00000093009
dgkza
diacylglycerol kinase, zeta a
chr24_+_10039165 1.08 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr18_+_10784730 1.08 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr16_-_16225260 1.07 ENSDART00000165790
gra
granulito
chr9_+_10014514 1.07 ENSDART00000185590
nxph2a
neurexophilin 2a
chr7_-_39378903 1.07 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr18_-_24989580 1.06 ENSDART00000163449
chd2
chromodomain helicase DNA binding protein 2
chr15_-_35246742 1.06 ENSDART00000131479
mff
mitochondrial fission factor
chr8_-_19649617 1.05 ENSDART00000189033
fam78bb
family with sequence similarity 78, member B b
chr11_+_18873113 1.05 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr14_-_6402769 1.03 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr11_-_41996957 1.03 ENSDART00000055706
her15.2
hairy and enhancer of split-related 15, tandem duplicate 2
chr1_+_28031697 1.03 ENSDART00000047211
ENSDART00000149785
ENSDART00000149817
ENSDART00000149479
ENSDART00000187922
chst10
carbohydrate sulfotransferase 10
chr25_+_7532627 1.02 ENSDART00000187660
ptdss2
phosphatidylserine synthase 2
chr17_+_10593398 1.01 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr6_-_18121075 1.01 ENSDART00000171072
SEC14L1
si:dkey-237i9.1
chr7_-_30492261 1.01 ENSDART00000173954
adam10a
ADAM metallopeptidase domain 10a
chr3_+_22327738 1.01 ENSDART00000055675
gh1
growth hormone 1
chr12_+_49100365 0.98 ENSDART00000171905
CABZ01075125.1

chr6_-_39218609 0.95 ENSDART00000133305
os9
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr5_+_26847190 0.95 ENSDART00000076742
imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr8_-_45430817 0.92 ENSDART00000150067
ENSDART00000112394
ywhabb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b
chr21_-_44104600 0.91 ENSDART00000044599
oatx
organic anion transporter X
chr13_-_36844945 0.89 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr21_-_40317035 0.89 ENSDART00000143648
ENSDART00000013359
or101-1
odorant receptor, family B, subfamily 101, member 1
chr24_-_8730913 0.86 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
tfap2a
transcription factor AP-2 alpha
chr3_+_34140507 0.84 ENSDART00000131802
si:dkey-204f11.64
si:dkey-204f11.64
chr23_+_5465806 0.84 ENSDART00000149434
ENSDART00000148506
tulp1a
tubby like protein 1a
chr21_-_40562705 0.81 ENSDART00000158289
ENSDART00000171997
taok1b
TAO kinase 1b
chr8_+_18545933 0.80 ENSDART00000148806
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr11_+_29770966 0.80 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr18_+_3634652 0.80 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr6_-_1780633 0.79 ENSDART00000160670
ntan1
N-terminal asparagine amidase
chr20_+_18260358 0.79 ENSDART00000187734
ENSDART00000191947
ENSDART00000057039
taf4b
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_+_37623693 0.79 ENSDART00000144812
ENSDART00000182709
tubgcp5
tubulin, gamma complex associated protein 5
chr1_-_45580787 0.79 ENSDART00000135089
atf7ip
activating transcription factor 7 interacting protein
chr1_-_58766424 0.79 ENSDART00000191010
CABZ01096573.1

chr23_+_21492151 0.79 ENSDART00000025487
icmt
isoprenylcysteine carboxyl methyltransferase
chr16_+_33987892 0.78 ENSDART00000166302
pigv
phosphatidylinositol glycan anchor biosynthesis, class V
chr4_-_908821 0.78 ENSDART00000168266
mrap2b
melanocortin 2 receptor accessory protein 2b
chr10_+_26652859 0.77 ENSDART00000079174
htatsf1
HIV-1 Tat specific factor 1
chr10_+_4875262 0.76 ENSDART00000165942
palm2
paralemmin 2
chr11_-_27702778 0.75 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr22_+_5176255 0.75 ENSDART00000092647
cers1
ceramide synthase 1
chr14_+_11289851 0.74 ENSDART00000113567
rlim
ring finger protein, LIM domain interacting
chr12_-_33659328 0.74 ENSDART00000153457
tmem94
transmembrane protein 94
chr5_-_40910749 0.73 ENSDART00000083467
ENSDART00000133183
parp8
poly (ADP-ribose) polymerase family, member 8
chr9_+_3519191 0.71 ENSDART00000008606
mettl8
methyltransferase like 8
chr8_+_31435452 0.70 ENSDART00000145282
selenop
selenoprotein P
chr22_+_2431585 0.70 ENSDART00000167758
zgc:171435
zgc:171435
chr5_+_61799629 0.70 ENSDART00000113508
hnrnpul1l
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr21_-_2209012 0.70 ENSDART00000158345
zgc:162971
zgc:162971
chr9_-_8314028 0.67 ENSDART00000102739
si:ch211-145c1.1
si:ch211-145c1.1
chr12_-_9084640 0.66 ENSDART00000125230
exoc6
exocyst complex component 6
chr5_+_51833305 0.65 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr1_+_44523516 0.64 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr14_+_21754521 0.62 ENSDART00000111839
kdm2ab
lysine (K)-specific demethylase 2Ab
chr15_-_26930999 0.62 ENSDART00000181674
ENSDART00000126046
ccdc9
coiled-coil domain containing 9
chr25_+_29694158 0.61 ENSDART00000174568
brd1b
bromodomain containing 1b
chr5_-_65081600 0.61 ENSDART00000160850
inpp5e
inositol polyphosphate-5-phosphatase E
chr21_+_11367253 0.61 ENSDART00000091835
gtf3c5
general transcription factor IIIC, polypeptide 5
chr7_-_26518086 0.60 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr14_+_14027427 0.58 ENSDART00000183204
rraga
Ras-related GTP binding A
chr18_+_19006063 0.58 ENSDART00000135729
slc24a1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr6_+_54538948 0.58 ENSDART00000149270
tulp1b
tubby like protein 1b
chr3_+_22999849 0.56 ENSDART00000127239
si:ch211-237i5.4
si:ch211-237i5.4
chr2_-_51757328 0.56 ENSDART00000189286
si:ch211-9d9.1
si:ch211-9d9.1
chr8_+_53120278 0.55 ENSDART00000125232
nr2c2
nuclear receptor subfamily 2, group C, member 2
chr8_+_2456854 0.54 ENSDART00000133938
ENSDART00000002764
polb
polymerase (DNA directed), beta
chr11_+_6295370 0.53 ENSDART00000139882
ranbp3a
RAN binding protein 3a
chr25_-_10629940 0.53 ENSDART00000154483
ENSDART00000155231
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr5_+_9434288 0.52 ENSDART00000162089
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr9_+_19095023 0.52 ENSDART00000110457
ENSDART00000099426
ENSDART00000137087
crfb1
cytokine receptor family member b1
chr22_-_38934989 0.51 ENSDART00000008365
ncbp2
nuclear cap binding protein subunit 2
chr13_+_31002658 0.50 ENSDART00000140257
lrrc18a
leucine rich repeat containing 18a
chr4_-_18455480 0.50 ENSDART00000150221
sco2
SCO2 cytochrome c oxidase assembly protein
chr5_-_32489796 0.48 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr3_+_50602866 0.46 ENSDART00000190069
ENSDART00000153921
gsg1l2a
gsg1-like 2a
chr22_+_5176693 0.46 ENSDART00000160927
cers1
ceramide synthase 1
chr20_+_42537768 0.45 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
si:dkeyp-93d12.1
chr10_-_41400049 0.45 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr4_-_56083825 0.44 ENSDART00000157710
znf986
zinc finger protein 986
chr16_+_54592907 0.44 ENSDART00000172113
dennd4b
DENN/MADD domain containing 4B
chr4_-_28353538 0.44 ENSDART00000064219
trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr22_-_619711 0.41 ENSDART00000192778
srsf3b
serine/arginine-rich splicing factor 3b
chr20_-_45423498 0.40 ENSDART00000098424
trib2
tribbles pseudokinase 2
chr23_+_30827959 0.39 ENSDART00000033429
npbwr2a
neuropeptides B/W receptor 2a
chr2_+_30721070 0.38 ENSDART00000099052
si:dkey-94e7.2
si:dkey-94e7.2
chr7_+_20030888 0.38 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr5_-_23715861 0.38 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of crx+otx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
1.5 4.5 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
1.4 6.8 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.1 4.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 1.1 GO:0016264 gap junction assembly(GO:0016264)
0.3 2.9 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.3 4.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.3 2.1 GO:0043584 nose development(GO:0043584)
0.2 0.7 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 1.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.2 1.8 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.2 1.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 3.6 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.2 1.0 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.2 3.1 GO:0046549 retinal cone cell development(GO:0046549)
0.2 0.6 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.2 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.2 1.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 0.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.2 0.5 GO:0032241 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.2 2.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 4.1 GO:0030497 fatty acid elongation(GO:0030497)
0.2 1.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 1.8 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 1.7 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 0.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 1.7 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 5.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 2.2 GO:0032438 melanosome organization(GO:0032438)
0.1 1.3 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 2.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.4 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 1.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.3 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.8 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 0.8 GO:0097009 energy homeostasis(GO:0097009)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.9 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.3 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 0.8 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 2.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.0 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.8 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.3 GO:0060872 semicircular canal development(GO:0060872)
0.0 3.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.8 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 1.4 GO:0061512 protein localization to cilium(GO:0061512)
0.0 2.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284) double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.6 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 4.8 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.0 0.6 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 1.0 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.2 GO:0009615 response to virus(GO:0009615)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:0005955 calcineurin complex(GO:0005955)
0.5 4.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.3 GO:0001650 fibrillar center(GO:0001650)
0.3 0.9 GO:0034457 Mpp10 complex(GO:0034457)
0.3 6.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.8 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 0.8 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.6 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.5 GO:0034518 RNA cap binding complex(GO:0034518)
0.1 2.7 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 2.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 6.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.1 GO:0043186 P granule(GO:0043186)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 4.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 3.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 6.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.4 4.3 GO:0038046 enkephalin receptor activity(GO:0038046)
1.0 4.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.7 2.9 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.7 4.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 3.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 2.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 1.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.4 3.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 1.0 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.3 4.8 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.3 1.0 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.3 1.3 GO:0016531 copper chaperone activity(GO:0016531)
0.3 1.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 2.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.8 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 1.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 0.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 0.7 GO:0008430 selenium binding(GO:0008430)
0.2 0.5 GO:0004904 interferon receptor activity(GO:0004904)
0.2 2.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.3 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 6.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 2.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 6.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.8 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.7 GO:0010181 FMN binding(GO:0010181)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 2.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.6 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.1 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 3.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 5.8 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 2.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 1.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 6.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.4 6.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 2.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 4.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping