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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for cxxc1a+cxxc1b+mbd1a

Z-value: 0.14

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Transcription factors associated with cxxc1a+cxxc1b+mbd1a

Gene Symbol Gene ID Gene Info
cxxc1b
ENSDARG00000025718 CXXC finger protein 1b
mbd1a
ENSDARG00000101205 methyl-CpG binding domain protein 1a
cxxc1a
ENSDARG00000101996 CXXC finger protein 1a
cxxc1b
ENSDARG00000111907 CXXC finger protein 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cxxc1adr11_v1_chr8_+_7854130_7854130-0.431.7e-05Click!
cxxc1bdr11_v1_chr11_+_25539698_25539698-0.372.5e-04Click!
mbd1adr11_v1_chr8_+_7875110_7875142-0.372.8e-04Click!

Activity profile of cxxc1a+cxxc1b+mbd1a motif

Sorted Z-values of cxxc1a+cxxc1b+mbd1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_38509333 0.61 ENSDART00000153482
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr23_-_20345473 0.46 ENSDART00000140935
si:rp71-17i16.6
si:rp71-17i16.6
chr21_+_27448856 0.46 ENSDART00000100784
cfbl
complement factor b-like
chr11_+_44579865 0.43 ENSDART00000173425
nid1b
nidogen 1b
chr21_-_28901095 0.38 ENSDART00000180820
cxxc5a
CXXC finger protein 5a
chr22_-_6988102 0.33 ENSDART00000185618
fgfr1bl
fibroblast growth factor receptor 1b, like
chr1_-_55166511 0.32 ENSDART00000150430
ENSDART00000035725
pane1
proliferation associated nuclear element
chr21_+_29179887 0.27 ENSDART00000161941
si:ch211-57b15.1
si:ch211-57b15.1
chr21_-_7995994 0.24 ENSDART00000151632
zgc:171965
zgc:171965
chr18_+_1145571 0.23 ENSDART00000135055
rec114
REC114 meiotic recombination protein
chr11_-_438492 0.23 ENSDART00000137121
ENSDART00000133784
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr17_+_3390772 0.21 ENSDART00000160073
sntg2
syntrophin, gamma 2
chr11_-_438294 0.10 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr5_+_23136544 0.07 ENSDART00000003428
ENSDART00000109340
ENSDART00000171039
ENSDART00000178821
prps1a
phosphoribosyl pyrophosphate synthetase 1A
chr3_-_19200571 0.06 ENSDART00000131503
ENSDART00000012335
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr17_+_26803470 0.05 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2
chr1_+_41690402 0.04 ENSDART00000177298
fbxo41
F-box protein 41
chr4_-_17278904 0.01 ENSDART00000178686
ENSDART00000135730
lrmp
lymphoid-restricted membrane protein

Network of associatons between targets according to the STRING database.

First level regulatory network of cxxc1a+cxxc1b+mbd1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions