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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for dlx1a

Z-value: 1.32

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Transcription factors associated with dlx1a

Gene Symbol Gene ID Gene Info
dlx1a
ENSDARG00000013125 distal-less homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx1adr11_v1_chr9_+_3388099_33880990.019.1e-01Click!

Activity profile of dlx1a motif

Sorted Z-values of dlx1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_12011390 20.04 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr15_-_46779934 15.67 ENSDART00000085136
clcn2c
chloride channel 2c
chr15_-_12011202 13.11 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
si:dkey-202l22.6
chr5_+_56023186 10.36 ENSDART00000156230
fzd9a
frizzled class receptor 9a
chr24_-_27452488 10.22 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr4_+_73085993 10.11 ENSDART00000165749
si:ch73-170d6.2
si:ch73-170d6.2
chr12_+_22580579 9.62 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr22_-_30770751 9.44 ENSDART00000172115
AL831726.2

chr23_+_20110086 9.08 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr22_+_19407531 8.73 ENSDART00000141060
si:dkey-78l4.2
si:dkey-78l4.2
chr14_-_4145594 8.70 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr5_-_30615901 8.54 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr11_+_11504014 8.33 ENSDART00000104264
ENSDART00000134806
ENSDART00000132291
zgc:171226
zgc:171226
chr18_+_5490668 8.14 ENSDART00000167035
mibp2
muscle-specific beta 1 integrin binding protein 2
chr19_+_43297546 8.14 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr20_+_10538025 8.12 ENSDART00000129762
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr5_-_42904329 8.12 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr12_-_35830625 8.08 ENSDART00000180028
CU459056.1

chr19_-_5699703 8.04 ENSDART00000082050
zgc:174904
zgc:174904
chr6_+_39098397 7.87 ENSDART00000003716
ENSDART00000188655
prss60.2
protease, serine, 60.2
chr24_-_25166720 7.55 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr8_+_22516728 7.35 ENSDART00000146013
si:ch211-261n11.3
si:ch211-261n11.3
chr17_-_37395460 7.30 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr4_+_7391110 7.27 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr16_-_45094599 7.26 ENSDART00000155479
si:rp71-77l1.1
si:rp71-77l1.1
chr22_+_11775269 7.24 ENSDART00000140272
krt96
keratin 96
chr24_-_38110779 7.14 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr1_+_53842344 7.08 ENSDART00000114506
crfb17
cytokine receptor family member B17
chr16_+_23403602 7.08 ENSDART00000159848
s100w
S100 calcium binding protein W
chr16_-_17713859 7.05 ENSDART00000149275
zgc:174935
zgc:174935
chr19_+_43780970 6.98 ENSDART00000063870
rpl11
ribosomal protein L11
chr4_-_9891874 6.92 ENSDART00000067193
adm2a
adrenomedullin 2a
chr10_+_17776981 6.89 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr18_-_977075 6.62 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr10_+_42358426 6.60 ENSDART00000025691
dbnla
drebrin-like a
chr1_+_52392511 6.54 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr20_-_5291012 6.52 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr6_-_55399214 6.44 ENSDART00000168367
ctsa
cathepsin A
chr16_+_23431189 6.44 ENSDART00000004679
icn
ictacalcin
chr16_-_51271962 6.40 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr16_+_35916371 6.39 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr15_-_21877726 6.24 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr20_+_36812368 6.24 ENSDART00000062931
abracl
ABRA C-terminal like
chr12_-_4532066 6.22 ENSDART00000092687
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr10_-_22095505 6.15 ENSDART00000140210
ponzr10
plac8 onzin related protein 10
chr6_+_28752943 6.14 ENSDART00000078447
ENSDART00000146574
tprg1
tumor protein p63 regulated 1
chr20_+_38279523 6.13 ENSDART00000061311
ccl38a.5
chemokine (C-C motif) ligand 38, duplicate 5
chr20_+_10544100 6.12 ENSDART00000113927
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr25_+_13620555 6.07 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr7_+_6652967 6.02 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr1_-_58573646 6.00 ENSDART00000167777
adgre5b.3
adhesion G protein-coupled receptor E5b, duplicate 3
chr20_-_26822522 5.98 ENSDART00000146326
ENSDART00000046764
ENSDART00000103234
ENSDART00000143267
gmds
GDP-mannose 4,6-dehydratase
chr3_-_40973791 5.98 ENSDART00000136174
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr13_+_33688474 5.96 ENSDART00000161465
CABZ01087953.1

chr15_-_47848544 5.96 ENSDART00000098711
eif3k
eukaryotic translation initiation factor 3, subunit K
chr24_+_19415124 5.95 ENSDART00000186931
sulf1
sulfatase 1
chr25_+_31227747 5.88 ENSDART00000033872
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr5_-_55981288 5.88 ENSDART00000146616
si:dkey-189h5.6
si:dkey-189h5.6
chr22_-_10121880 5.81 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr23_-_5719453 5.80 ENSDART00000033093
lad1
ladinin
chr21_-_5205617 5.73 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr2_+_36112273 5.71 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr18_+_8912710 5.67 ENSDART00000142866
tmem243a
transmembrane protein 243, mitochondrial a
chr16_+_23404170 5.66 ENSDART00000170061
s100w
S100 calcium binding protein W
chr19_-_5372572 5.64 ENSDART00000151326
krt17
keratin 17
chr18_-_48550426 5.59 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr13_+_25397098 5.54 ENSDART00000132953
gsto2
glutathione S-transferase omega 2
chr24_-_34680956 5.42 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr1_-_18615063 5.41 ENSDART00000014916
klf3
Kruppel-like factor 3 (basic)
chr8_-_31107537 5.40 ENSDART00000098925
vgll4l
vestigial like 4 like
chr25_+_10410620 5.31 ENSDART00000151886
ehf
ets homologous factor
chr13_+_25396896 5.30 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr10_-_20445549 5.28 ENSDART00000064613
loxl2a
lysyl oxidase-like 2a
chr16_-_20312146 5.28 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr6_-_40842768 5.27 ENSDART00000076160
mustn1a
musculoskeletal, embryonic nuclear protein 1a
chr18_+_3037998 5.25 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr17_+_16046314 5.24 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr9_-_9415000 5.24 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr8_-_27656765 5.14 ENSDART00000078491
mov10b.2
Moloney leukemia virus 10b, tandem duplicate 2
chr20_-_33976305 5.12 ENSDART00000111022
sele
selectin E
chr23_-_24394719 5.12 ENSDART00000044918
epha2b
eph receptor A2 b
chr21_+_11244068 5.11 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr22_-_10541712 5.09 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr5_+_19343880 5.09 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr3_+_32492467 5.04 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr8_-_23612462 5.03 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr23_-_29569827 5.03 ENSDART00000078300
ENSDART00000133576
ENSDART00000158349
nmnat1-rbp7a
nmnat1
nmnat1-rbp7a readthrough
nicotinamide nucleotide adenylyltransferase 1
chr10_+_8690936 5.02 ENSDART00000144218
si:dkey-27b3.4
si:dkey-27b3.4
chr25_-_23526058 5.02 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr19_-_5669122 4.98 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr23_+_4709607 4.97 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr22_+_16308450 4.97 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr6_-_7720332 4.97 ENSDART00000135945
rpsa
ribosomal protein SA
chr19_+_41464870 4.94 ENSDART00000102778
dlx6a
distal-less homeobox 6a
chr18_-_48547564 4.93 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr1_+_45056371 4.90 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr21_+_43702016 4.90 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr20_-_8094718 4.89 ENSDART00000122902
si:ch211-232i5.3
si:ch211-232i5.3
chr25_-_21031007 4.87 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr20_-_49704915 4.86 ENSDART00000189232
COX7A2 (1 of many)
cytochrome c oxidase subunit 7A2
chr1_-_23308225 4.84 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr16_+_23975930 4.83 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr12_+_13319132 4.72 ENSDART00000049167
psme2
proteasome activator subunit 2
chr19_-_7690975 4.72 ENSDART00000151384
si:dkey-204a24.10
si:dkey-204a24.10
chr17_+_16046132 4.69 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr9_-_712308 4.65 ENSDART00000144625
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr12_-_48188928 4.64 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr21_+_19635486 4.61 ENSDART00000185736
fgf10a
fibroblast growth factor 10a
chr15_-_43625549 4.61 ENSDART00000168589
ctsc
cathepsin C
chr19_+_2590182 4.60 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr12_-_46176115 4.55 ENSDART00000152848
si:ch211-226h7.8
si:ch211-226h7.8
chr21_-_39024754 4.54 ENSDART00000056878
traf4b
tnf receptor-associated factor 4b
chr21_-_20932603 4.54 ENSDART00000138155
ENSDART00000079709
c6
complement component 6
chr16_+_23799622 4.49 ENSDART00000046922
rab13
RAB13, member RAS oncogene family
chr22_-_16154771 4.48 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr13_+_7442023 4.47 ENSDART00000080975
tnfaip2b
tumor necrosis factor, alpha-induced protein 2b
chr23_+_4689626 4.43 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr9_+_30421489 4.41 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr18_+_26422124 4.40 ENSDART00000060245
ctsh
cathepsin H
chr4_-_77218637 4.39 ENSDART00000174325
psmb10
proteasome subunit beta 10
chr23_-_33350990 4.38 ENSDART00000144831
si:ch211-226m16.2
si:ch211-226m16.2
chr8_-_36287046 4.36 ENSDART00000162877
si:busm1-194e12.11
si:busm1-194e12.11
chr5_+_6672870 4.35 ENSDART00000126598
pxna
paxillin a
chr3_-_18744511 4.34 ENSDART00000145539
zgc:113333
zgc:113333
chr17_+_24851951 4.29 ENSDART00000180746
cx35.4
connexin 35.4
chr12_-_25294096 4.28 ENSDART00000183398
hcar1-4
hydroxycarboxylic acid receptor 1-4
chr10_+_29840725 4.24 ENSDART00000127268
BX120005.1

chr19_+_823945 4.20 ENSDART00000142287
ppp1r18
protein phosphatase 1, regulatory subunit 18
chr13_-_31008275 4.17 ENSDART00000139394
wdfy4
WDFY family member 4
chr6_+_24398907 4.17 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr4_-_17669881 4.12 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr2_+_40181633 4.11 ENSDART00000185494
FP236331.1

chr16_+_42471455 4.10 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr15_-_33965440 4.10 ENSDART00000163841
lsr
lipolysis stimulated lipoprotein receptor
chr5_+_27897504 4.10 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr14_-_33481428 4.06 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr21_-_44081540 4.00 ENSDART00000130833
FO704810.1

chr5_+_27898226 3.95 ENSDART00000098604
ENSDART00000180251
adam28
ADAM metallopeptidase domain 28
chr22_+_16308806 3.94 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr23_+_39695827 3.94 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr21_+_25236297 3.94 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr13_-_330004 3.94 ENSDART00000093149
ddx21
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr10_+_21867307 3.91 ENSDART00000126629
cbln17
cerebellin 17
chr11_-_44194132 3.91 ENSDART00000182954
ENSDART00000111271
CABZ01080074.1

chr11_+_37250839 3.89 ENSDART00000170209
il17rc
interleukin 17 receptor C
chr6_+_41191482 3.88 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr11_-_11890001 3.87 ENSDART00000081544
wipf2a
WAS/WASL interacting protein family, member 2a
chr22_-_1079773 3.87 ENSDART00000136668
si:ch1073-15f12.3
si:ch1073-15f12.3
chr4_+_16715267 3.85 ENSDART00000143849
pkp2
plakophilin 2
chr13_+_646700 3.80 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr16_-_12688957 3.80 ENSDART00000147854
ENSDART00000184587
mfap5
microfibril associated protein 5
chr1_-_37377509 3.73 ENSDART00000113542
tnip2
TNFAIP3 interacting protein 2
chr23_-_1017605 3.69 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr12_-_26538823 3.68 ENSDART00000143213
acsf2
acyl-CoA synthetase family member 2
chr11_+_1602916 3.67 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr17_-_38291065 3.67 ENSDART00000152056
pax9
paired box 9
chr16_-_21810668 3.66 ENSDART00000156575
dicp3.3
diverse immunoglobulin domain-containing protein 3.3
chr1_-_9195629 3.65 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr5_+_27404946 3.65 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr21_-_11654422 3.64 ENSDART00000081614
ENSDART00000132699
cast
calpastatin
chr2_+_52232630 3.64 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr18_+_8912536 3.63 ENSDART00000134827
ENSDART00000061904
tmem243a
transmembrane protein 243, mitochondrial a
chr3_-_25268751 3.61 ENSDART00000139423
mgat3a
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr20_-_40755614 3.61 ENSDART00000061247
cx32.3
connexin 32.3
chr10_-_13343831 3.58 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr17_-_20118145 3.57 ENSDART00000149737
ENSDART00000165606
ryr2b
ryanodine receptor 2b (cardiac)
chr17_-_32413147 3.56 ENSDART00000149102
grhl1
grainyhead-like transcription factor 1
chr3_+_27798094 3.55 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr21_-_32060993 3.54 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr16_+_23976227 3.54 ENSDART00000193013
apoc4
apolipoprotein C-IV
chr24_+_21621654 3.54 ENSDART00000002595
rpl21
ribosomal protein L21
chr4_+_77709678 3.54 ENSDART00000036856
AL935186.1

chr19_-_340347 3.52 ENSDART00000139924
golph3l
golgi phosphoprotein 3-like
chr7_-_13648635 3.52 ENSDART00000148957
ENSDART00000130967
spg21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr4_+_6032640 3.52 ENSDART00000157487
tfec
transcription factor EC
chr11_-_6877973 3.51 ENSDART00000160271
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr16_-_26676685 3.51 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr19_+_770300 3.50 ENSDART00000062518
gstr
glutathione S-transferase rho
chr2_-_23768818 3.50 ENSDART00000148685
ENSDART00000191167
xirp1
xin actin binding repeat containing 1
chr1_+_58922027 3.48 ENSDART00000159479
trip10b
thyroid hormone receptor interactor 10b
chr18_+_8912113 3.48 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr6_+_12922002 3.48 ENSDART00000080350
ENSDART00000149018
cxcr4a
chemokine (C-X-C motif) receptor 4a
chr24_-_32582880 3.47 ENSDART00000186307
rdh12l
retinol dehydrogenase 12, like
chr13_+_35339182 3.46 ENSDART00000019323
jag1b
jagged 1b
chr10_+_17714866 3.44 ENSDART00000039969
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr23_+_19813677 3.42 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr9_+_41156818 3.41 ENSDART00000105764
ENSDART00000147052
stat4
signal transducer and activator of transcription 4
chr17_-_7733037 3.41 ENSDART00000064657
stx11a
syntaxin 11a
chr5_-_38777852 3.40 ENSDART00000131603
si:dkey-58f10.4
si:dkey-58f10.4
chr11_+_40812590 3.40 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr11_+_705727 3.40 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr22_-_10158038 3.39 ENSDART00000047444
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr6_-_43283122 3.38 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr3_-_29899172 3.38 ENSDART00000140518
ENSDART00000020311
rpl27
ribosomal protein L27
chr7_+_8361083 3.37 ENSDART00000102091
jac7
jacalin 7
chr20_+_35484070 3.35 ENSDART00000026234
ENSDART00000141675
mep1a.2
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr9_+_41080029 3.32 ENSDART00000141179
ENSDART00000019289
zgc:136439
zgc:136439
chr4_+_70151160 3.31 ENSDART00000111816
si:dkey-3h2.4
si:dkey-3h2.4
chr25_+_3104959 3.31 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr11_-_7380674 3.31 ENSDART00000014979
ENSDART00000103418
vtg3
vitellogenin 3, phosvitinless

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0002369 T cell cytokine production(GO:0002369)
2.4 7.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
1.6 4.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.6 6.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.5 6.0 GO:0021564 vagus nerve development(GO:0021564)
1.3 5.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.3 6.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.3 5.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.3 5.0 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
1.2 6.2 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.2 3.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
1.2 3.7 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
1.2 4.6 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.1 4.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.1 6.7 GO:0048194 Golgi vesicle budding(GO:0048194)
1.1 4.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
1.1 2.1 GO:0034377 plasma lipoprotein particle assembly(GO:0034377) protein-lipid complex assembly(GO:0065005)
1.1 5.3 GO:0035988 chondrocyte proliferation(GO:0035988)
1.0 5.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.0 15.7 GO:0030216 keratinocyte differentiation(GO:0030216)
1.0 2.9 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
1.0 5.8 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.9 2.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.9 6.8 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.8 2.5 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.8 3.3 GO:0030224 monocyte differentiation(GO:0030224)
0.8 5.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.8 5.6 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.8 2.4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.7 2.9 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.7 3.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.7 2.9 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.7 2.8 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.7 3.5 GO:0060231 mesenchymal to epithelial transition(GO:0060231) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.7 7.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.7 2.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.7 3.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.7 2.7 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.7 2.0 GO:0060923 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.6 4.3 GO:0061055 myotome development(GO:0061055)
0.6 3.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.6 3.0 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.6 5.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 3.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.6 3.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6 1.7 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.5 3.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 2.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.5 16.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.5 2.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.5 2.6 GO:0090527 actin filament reorganization(GO:0090527)
0.5 2.1 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.5 2.6 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.5 2.0 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.5 3.0 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.5 2.0 GO:0099563 modification of synaptic structure(GO:0099563)
0.5 2.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 1.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 1.9 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.5 24.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 1.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.5 2.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.4 9.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 4.5 GO:0051601 exocyst localization(GO:0051601)
0.4 2.7 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.4 25.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.4 6.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.4 2.6 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 2.5 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.4 2.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.4 1.6 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.4 4.3 GO:0006032 chitin catabolic process(GO:0006032)
0.4 7.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.4 4.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.4 2.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.4 1.1 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.4 1.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.4 5.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.4 26.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.4 8.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 6.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.3 3.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.3 1.7 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.3 1.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 1.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 4.3 GO:0009303 rRNA transcription(GO:0009303)
0.3 1.3 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.3 1.6 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.3 1.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 2.5 GO:0034063 stress granule assembly(GO:0034063)
0.3 1.6 GO:1902804 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 4.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.3 6.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 1.5 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.3 2.1 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3 8.0 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.3 3.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.3 2.6 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.3 2.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 1.4 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 2.0 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 0.8 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 10.1 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.3 1.1 GO:0015871 choline transport(GO:0015871)
0.3 1.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.3 0.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.3 2.7 GO:0031579 membrane raft assembly(GO:0001765) membrane raft organization(GO:0031579) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.3 2.6 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.3 1.3 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 5.0 GO:0006446 regulation of translational initiation(GO:0006446)
0.3 4.8 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.7 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 3.5 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.2 1.0 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 1.7 GO:0040016 embryonic cleavage(GO:0040016) positive regulation of myoblast fusion(GO:1901741)
0.2 4.8 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.2 1.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.2 0.7 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.2 7.4 GO:0051014 actin filament severing(GO:0051014)
0.2 5.4 GO:0035141 medial fin morphogenesis(GO:0035141)
0.2 0.7 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 1.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 2.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 3.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 1.3 GO:0097065 anterior head development(GO:0097065)
0.2 2.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.7 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.8 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 4.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.2 0.6 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.2 0.6 GO:0097435 fibril organization(GO:0097435)
0.2 5.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 2.2 GO:0050909 sensory perception of taste(GO:0050909)
0.2 6.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 10.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.2 1.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 1.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 1.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 1.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.2 1.7 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.2 3.7 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.2 10.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 3.4 GO:0060021 palate development(GO:0060021)
0.2 0.9 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 2.8 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 1.0 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.2 1.0 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 3.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 2.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 1.8 GO:0032264 IMP salvage(GO:0032264)
0.2 2.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 1.6 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 4.5 GO:0019835 cytolysis(GO:0019835)
0.2 4.6 GO:0006829 zinc II ion transport(GO:0006829)
0.2 0.9 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 8.8 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.2 2.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 5.0 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 5.2 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.3 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 8.6 GO:0001570 vasculogenesis(GO:0001570)
0.1 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.5 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.1 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.0 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 3.7 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 1.1 GO:0031179 peptide modification(GO:0031179)
0.1 2.0 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 3.3 GO:0032355 response to estradiol(GO:0032355)
0.1 0.7 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.5 GO:0051645 Golgi localization(GO:0051645)
0.1 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 2.0 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 1.0 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 1.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 5.3 GO:0050673 epithelial cell proliferation(GO:0050673)
0.1 0.6 GO:0046931 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.1 1.2 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 1.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.8 GO:0048665 neuron fate specification(GO:0048665)
0.1 1.2 GO:0001840 neural plate development(GO:0001840)
0.1 3.8 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.1 0.9 GO:1901998 toxin transport(GO:1901998)
0.1 1.2 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.2 GO:0051055 negative regulation of lipid biosynthetic process(GO:0051055)
0.1 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.9 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 1.0 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 1.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 1.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.5 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 6.2 GO:1990266 neutrophil migration(GO:1990266)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.6 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.6 GO:0036372 opsin transport(GO:0036372)
0.1 2.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 0.4 GO:1903076 regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.1 1.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 5.0 GO:0001666 response to hypoxia(GO:0001666)
0.1 0.9 GO:0042531 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 1.0 GO:0009651 response to salt stress(GO:0009651)
0.1 1.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 3.1 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 2.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.0 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.5 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 5.1 GO:0031101 fin regeneration(GO:0031101)
0.1 1.1 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
0.1 1.9 GO:0050821 protein stabilization(GO:0050821)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.7 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.1 1.5 GO:0007050 cell cycle arrest(GO:0007050)
0.1 7.3 GO:0042742 defense response to bacterium(GO:0042742)
0.1 4.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 6.8 GO:0006364 rRNA processing(GO:0006364)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.0 2.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 2.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 3.1 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.1 GO:1903726 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219) negative regulation of phospholipid metabolic process(GO:1903726)
0.0 12.8 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.8 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 2.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 2.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 3.5 GO:0031497 nucleosome assembly(GO:0006334) chromatin assembly(GO:0031497)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 2.4 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 3.6 GO:0001756 somitogenesis(GO:0001756)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 1.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.3 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 2.0 GO:0007492 endoderm development(GO:0007492)
0.0 0.4 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 2.6 GO:0001894 tissue homeostasis(GO:0001894)
0.0 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.8 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 2.1 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 3.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 0.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.3 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.3 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.1 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.0 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 2.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.7 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 3.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 2.3 GO:0008033 tRNA processing(GO:0008033)
0.0 1.4 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.5 GO:0006826 iron ion transport(GO:0006826)
0.0 26.7 GO:0006508 proteolysis(GO:0006508)
0.0 2.9 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.9 GO:0008366 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366) myelination(GO:0042552)
0.0 0.3 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 1.0 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.9 GO:0030218 erythrocyte differentiation(GO:0030218) erythrocyte homeostasis(GO:0034101)
0.0 0.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.5 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.1 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of hormone metabolic process(GO:0032350) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.5 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.3 GO:0060026 convergent extension(GO:0060026)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
1.3 5.2 GO:0019815 B cell receptor complex(GO:0019815)
1.2 4.9 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.2 3.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.2 4.7 GO:0008537 proteasome activator complex(GO:0008537)
1.1 3.4 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
1.0 3.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.9 3.5 GO:0033186 CAF-1 complex(GO:0033186)
0.8 3.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.7 2.0 GO:0005960 glycine cleavage complex(GO:0005960)
0.6 8.4 GO:0042627 chylomicron(GO:0042627)
0.6 25.3 GO:0005861 troponin complex(GO:0005861)
0.6 2.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.5 2.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 2.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.5 6.6 GO:0002102 podosome(GO:0002102)
0.4 8.8 GO:0031430 M band(GO:0031430)
0.4 2.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 3.4 GO:0071797 LUBAC complex(GO:0071797)
0.4 3.3 GO:0000974 Prp19 complex(GO:0000974)
0.4 2.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 2.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 4.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 3.8 GO:0014704 intercalated disc(GO:0014704)
0.3 1.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 7.5 GO:0045180 basal cortex(GO:0045180)
0.3 8.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 1.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 4.5 GO:0005579 membrane attack complex(GO:0005579)
0.3 13.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 0.8 GO:1990879 CST complex(GO:1990879)
0.3 0.8 GO:0034457 Mpp10 complex(GO:0034457)
0.3 3.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 2.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 3.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2 6.4 GO:0005839 proteasome core complex(GO:0005839)
0.2 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 13.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 2.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 2.1 GO:0045095 keratin filament(GO:0045095)
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 2.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 1.1 GO:0016589 NURF complex(GO:0016589)
0.2 5.8 GO:0043186 P granule(GO:0043186)
0.2 0.7 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.2 2.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 10.1 GO:0001726 ruffle(GO:0001726)
0.2 14.1 GO:0005882 intermediate filament(GO:0005882)
0.2 4.3 GO:0000145 exocyst(GO:0000145)
0.1 7.6 GO:0005902 microvillus(GO:0005902)
0.1 3.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 7.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 2.1 GO:0042555 MCM complex(GO:0042555)
0.1 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.3 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.1 2.6 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 11.5 GO:0044420 extracellular matrix component(GO:0044420)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 13.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 7.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 1.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 6.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 8.4 GO:0005795 Golgi stack(GO:0005795)
0.1 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 13.6 GO:0000323 lytic vacuole(GO:0000323)
0.1 4.7 GO:0030496 midbody(GO:0030496)
0.1 0.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.7 GO:0032040 small-subunit processome(GO:0032040)
0.1 4.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 9.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 14.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 87.0 GO:0005615 extracellular space(GO:0005615)
0.1 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 3.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 7.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 3.9 GO:0031201 SNARE complex(GO:0031201)
0.1 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 7.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0043596 nuclear replication fork(GO:0043596)
0.0 9.6 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 4.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 3.6 GO:0010008 endosome membrane(GO:0010008)
0.0 1.9 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 4.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 5.2 GO:0044431 Golgi apparatus part(GO:0044431)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
2.0 8.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.7 5.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
1.3 6.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.3 5.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.2 6.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.2 3.7 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
1.1 6.5 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
1.1 5.4 GO:0001223 transcription coactivator binding(GO:0001223)
1.1 7.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
1.0 4.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.9 15.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.8 5.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.8 2.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.8 4.1 GO:0009374 biotin binding(GO:0009374)
0.8 2.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.8 5.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.8 4.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.8 3.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.8 3.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.8 2.3 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.8 10.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 3.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.7 6.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.7 6.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 2.7 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.7 4.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.6 3.8 GO:0019215 intermediate filament binding(GO:0019215)
0.6 3.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 10.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 3.7 GO:0042169 SH2 domain binding(GO:0042169)
0.6 10.0 GO:0031730 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730)
0.6 1.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 1.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.5 6.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 2.7 GO:0039706 co-receptor binding(GO:0039706)
0.5 2.1 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.5 2.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.5 2.5 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.5 14.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 2.0 GO:0033149 FFAT motif binding(GO:0033149)
0.5 4.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 3.3 GO:0045735 nutrient reservoir activity(GO:0045735)
0.5 1.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.5 14.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.5 8.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 3.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 6.2 GO:0002020 protease binding(GO:0002020)
0.4 1.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.4 1.3 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.4 3.9 GO:0008494 translation activator activity(GO:0008494)
0.4 3.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.4 5.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 8.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.4 5.9 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4 8.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 4.3 GO:0004568 chitinase activity(GO:0004568)
0.4 1.2 GO:0072545 tyrosine binding(GO:0072545)
0.4 5.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 3.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.4 3.0 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.4 2.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.4 7.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 1.8 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.4 6.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.4 2.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 3.1 GO:0048039 ubiquinone binding(GO:0048039)
0.3 7.3 GO:0042056 chemoattractant activity(GO:0042056)
0.3 2.3 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.3 1.9 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.3 5.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.2 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.3 3.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 2.6 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.3 5.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.3 7.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 1.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 3.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 1.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169) lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.2 3.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 2.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 5.0 GO:0043236 laminin binding(GO:0043236)
0.2 27.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.1 GO:0005542 folic acid binding(GO:0005542)
0.2 2.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 1.8 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.7 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 1.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 2.6 GO:0031720 haptoglobin binding(GO:0031720)
0.2 1.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 3.8 GO:0002039 p53 binding(GO:0002039)
0.2 0.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 0.6 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.2 1.6 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 2.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 1.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 1.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 3.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 1.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 0.9 GO:0050699 WW domain binding(GO:0050699)
0.2 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 3.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 2.1 GO:0015929 hyalurononglucosaminidase activity(GO:0004415) hexosaminidase activity(GO:0015929)
0.2 0.8 GO:0008430 selenium binding(GO:0008430)
0.2 4.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 2.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 5.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 4.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 3.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.4 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.2 7.1 GO:0015485 cholesterol binding(GO:0015485)
0.2 3.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 29.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 2.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 3.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 2.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 9.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 3.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 2.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 6.9 GO:0043022 ribosome binding(GO:0043022)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.8 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 9.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 4.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 9.6 GO:0003724 RNA helicase activity(GO:0003724)
0.1 2.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0032052 bile acid binding(GO:0032052)
0.1 1.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 10.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 16.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 4.3 GO:0000049 tRNA binding(GO:0000049)
0.1 12.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 23.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 4.0 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.1 3.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 2.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 6.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 4.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.0 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 1.2 GO:0030507 spectrin binding(GO:0030507)
0.1 4.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 4.7 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.1 4.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 4.9 GO:0048029 monosaccharide binding(GO:0048029)
0.1 10.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.3 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 1.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.1 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 1.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.5 GO:0015198 oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673) dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 2.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 3.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 4.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 6.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 9.7 GO:0005179 hormone activity(GO:0005179)
0.1 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 20.5 GO:0051015 actin filament binding(GO:0051015)
0.1 10.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.8 GO:0019843 rRNA binding(GO:0019843)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 2.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 4.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.8 GO:0032190 acrosin binding(GO:0032190)
0.0 3.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 2.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 3.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 7.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 11.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.3 GO:0042562 hormone binding(GO:0042562)
0.0 19.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 1.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 3.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 3.6 GO:0042277 peptide binding(GO:0042277)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0008236 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.1 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 1.2 GO:0008170 N-methyltransferase activity(GO:0008170)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.4 5.8 PID CONE PATHWAY Visual signal transduction: Cones
0.4 8.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 8.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 1.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 9.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 3.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 3.4 PID IL23 PATHWAY IL23-mediated signaling events
0.2 8.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 5.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 4.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 27.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.8 PID RAS PATHWAY Regulation of Ras family activation
0.2 4.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 7.4 PID P53 REGULATION PATHWAY p53 pathway
0.1 5.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.8 PID FGF PATHWAY FGF signaling pathway
0.1 3.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID EPO PATHWAY EPO signaling pathway
0.1 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 6.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 4.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.3 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.6 7.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.6 4.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 4.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 22.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 2.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 8.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 5.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 4.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 1.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 2.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 2.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 4.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 3.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 19.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 9.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 10.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 2.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 12.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 1.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 2.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 2.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 3.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 2.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 3.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 1.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.1 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.1 3.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.4 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 1.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.7 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 1.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 6.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.0 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 3.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism