Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for e2f2_e2f5

Z-value: 1.55

Motif logo

logo of logo of

Transcription factors associated with e2f2_e2f5

Gene Symbol Gene ID Gene Info
e2f2
ENSDARG00000079233 si_ch211-160f23.5
e2f5
ENSDARG00000038812 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e2f5dr11_v1_chr2_-_31686353_316864030.556.9e-09Click!
E2F2dr11_v1_chr17_-_27266053_272660530.431.7e-05Click!

Activity profile of e2f2_e2f5 motif

Sorted Z-values of e2f2_e2f5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_2892250 19.74 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr3_-_54607166 17.93 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr13_+_8255106 14.28 ENSDART00000080465
hells
helicase, lymphoid specific
chr11_-_11792766 13.90 ENSDART00000011657
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr20_+_39344889 13.89 ENSDART00000009164
esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr3_+_25999477 10.94 ENSDART00000024316
mcm5
minichromosome maintenance complex component 5
chr19_-_47571797 10.22 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr24_-_35561672 9.86 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr13_-_13030851 8.83 ENSDART00000009499
nsd2
nuclear receptor binding SET domain protein 2
chr1_+_19538299 8.43 ENSDART00000109416
smc2
structural maintenance of chromosomes 2
chr9_-_2892045 8.32 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr24_+_11908480 7.95 ENSDART00000024224
fen1
flap structure-specific endonuclease 1
chr7_+_55518519 7.17 ENSDART00000098476
ENSDART00000149915
cdt1
chromatin licensing and DNA replication factor 1
chr8_-_4760723 7.14 ENSDART00000064201
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr21_+_22558187 6.77 ENSDART00000167599
chek1
checkpoint kinase 1
chr19_-_47571456 6.65 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr1_-_8553165 6.11 ENSDART00000135197
ENSDART00000054981
zgc:112980
zgc:112980
chr24_+_11908833 6.08 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr15_-_17099560 5.64 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr10_-_21362071 5.60 ENSDART00000125167
avd
avidin
chr6_+_33931740 5.53 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr7_+_71535045 5.48 ENSDART00000047069
tyms
thymidylate synthetase
chr22_-_4439311 5.42 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr20_-_29498178 5.33 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr7_+_41812636 5.30 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr3_+_37112693 5.19 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
psmc3ip
PSMC3 interacting protein
chr20_+_23440632 5.08 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr20_-_29499363 5.06 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr9_+_22780901 4.96 ENSDART00000110992
ENSDART00000143972
rif1
replication timing regulatory factor 1
chr7_+_34236238 4.90 ENSDART00000052474
tipin
timeless interacting protein
chr24_+_23840821 4.83 ENSDART00000128595
ENSDART00000127188
pola1
polymerase (DNA directed), alpha 1
chr7_+_41812190 4.82 ENSDART00000113732
ENSDART00000174137
orc6
origin recognition complex, subunit 6
chr7_+_41812817 4.71 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr3_+_26244353 4.66 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr21_-_26490186 4.50 ENSDART00000009889
zgc:110540
zgc:110540
chr5_+_69950882 4.37 ENSDART00000097359
dnajc25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr5_-_54395488 4.34 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr5_+_12743640 4.33 ENSDART00000081411
pole
polymerase (DNA directed), epsilon
chr19_-_2582858 4.30 ENSDART00000113829
cdca7b
cell division cycle associated 7b
chr1_+_9199031 4.30 ENSDART00000092058
ENSDART00000182771
chtf18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr16_-_43335914 4.30 ENSDART00000111963
atad2
ATPase family, AAA domain containing 2
chr19_-_29294457 4.27 ENSDART00000130815
ENSDART00000103437
e2f3
E2F transcription factor 3
chr8_+_52415603 4.19 ENSDART00000021604
ENSDART00000191424
gins4
GINS complex subunit 4 (Sld5 homolog)
chr2_-_29923403 4.16 ENSDART00000144672
paxip1
PAX interacting (with transcription-activation domain) protein 1
chr7_-_69185124 4.09 ENSDART00000182217
ENSDART00000191359
usp10
ubiquitin specific peptidase 10
chr25_+_30196039 4.06 ENSDART00000005299
hsd17b12a
hydroxysteroid (17-beta) dehydrogenase 12a
chr25_-_35095129 4.01 ENSDART00000099866
ENSDART00000099868
kif15
kinesin family member 15
chr3_+_22335030 3.98 ENSDART00000055676
zgc:103564
zgc:103564
chr6_+_12968101 3.97 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr2_-_29923630 3.91 ENSDART00000158844
ENSDART00000031130
paxip1
PAX interacting (with transcription-activation domain) protein 1
chr20_+_35438300 3.91 ENSDART00000102504
ENSDART00000153249
tdrd6
tudor domain containing 6
chr2_-_38363017 3.79 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr18_-_5595546 3.68 ENSDART00000191825
cyp1a
cytochrome P450, family 1, subfamily A
chr1_-_46663997 3.62 ENSDART00000134450
ebpl
emopamil binding protein-like
chr22_-_10591876 3.60 ENSDART00000105846
si:dkey-42i9.8
si:dkey-42i9.8
chr2_-_44777592 3.60 ENSDART00000113351
ENSDART00000169310
ncapd2
non-SMC condensin I complex, subunit D2
chr13_-_35908275 3.57 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr24_-_11908115 3.50 ENSDART00000184329
tm9sf1
transmembrane 9 superfamily member 1
chr24_+_17345521 3.37 ENSDART00000024722
ENSDART00000154250
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr20_+_34770197 3.37 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr13_-_14929236 3.32 ENSDART00000020576
cdc25b
cell division cycle 25B
chr21_-_27413294 3.29 ENSDART00000131646
slc29a2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr4_-_5831522 3.25 ENSDART00000008898
foxm1
forkhead box M1
chr7_+_24814866 3.23 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr3_-_26244256 3.18 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr18_-_30499489 3.17 ENSDART00000033746
gins2
GINS complex subunit 2
chr4_+_1530287 3.00 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr2_-_44344321 2.98 ENSDART00000084174
lig1
ligase I, DNA, ATP-dependent
chr2_+_44512324 2.98 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr16_-_14587332 2.96 ENSDART00000012479
dscc1
DNA replication and sister chromatid cohesion 1
chr13_-_36863018 2.93 ENSDART00000023449
ENSDART00000149011
pygl
phosphorylase, glycogen, liver
chr4_+_18441988 2.77 ENSDART00000040827
ncaph2
non-SMC condensin II complex, subunit H2
chr19_+_9455218 2.72 ENSDART00000139385
si:ch211-288g17.3
si:ch211-288g17.3
chr9_-_12652984 2.72 ENSDART00000052256
sumo3b
small ubiquitin-like modifier 3b
chr13_-_35907768 2.71 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr5_+_58679071 2.71 ENSDART00000019561
zgc:171734
zgc:171734
chr8_-_13972626 2.70 ENSDART00000144296
serping1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr8_-_1219815 2.57 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr6_-_1762191 2.55 ENSDART00000167928
orc4
origin recognition complex, subunit 4
chr20_+_38201644 2.55 ENSDART00000022694
ehd3
EH-domain containing 3
chr9_-_30555725 2.55 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr5_+_32345187 2.47 ENSDART00000147132
c9
complement component 9
chr25_-_13403726 2.43 ENSDART00000056723
gins3
GINS complex subunit 3
chr19_-_2822372 2.38 ENSDART00000109130
ENSDART00000122385
recql4
RecQ helicase-like 4
chr15_-_19334448 2.36 ENSDART00000062576
thyn1
thymocyte nuclear protein 1
chr23_+_45339684 2.29 ENSDART00000149410
ENSDART00000102441
psip1b
PC4 and SFRS1 interacting protein 1b
chr16_+_28270037 2.25 ENSDART00000059035
mindy3
MINDY lysine 48 deubiquitinase 3
chr15_+_44184367 2.17 ENSDART00000162918
ENSDART00000110060
zgc:165514
zgc:165514
chr1_+_26677406 2.17 ENSDART00000183427
ENSDART00000180366
ENSDART00000181997
si:dkey-25o16.4
si:dkey-25o16.4
chr14_-_31715373 2.14 ENSDART00000127303
ENSDART00000173274
ENSDART00000173435
ENSDART00000172876
ENSDART00000173036
map7d3
MAP7 domain containing 3
chr22_-_10752471 2.14 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr7_+_24023653 2.13 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr14_-_35400671 2.06 ENSDART00000129676
lsm11
LSM11, U7 small nuclear RNA associated
chr18_+_14329231 2.05 ENSDART00000151641
zgc:173742
zgc:173742
chr5_-_33255759 2.05 ENSDART00000085531
prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr1_+_26676758 2.04 ENSDART00000152299
si:dkey-25o16.4
si:dkey-25o16.4
chr18_+_41560822 2.03 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr22_-_38274188 2.02 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr13_+_33462232 2.01 ENSDART00000177841
zgc:136302
zgc:136302
chr3_-_35865040 2.00 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr19_+_48060464 1.99 ENSDART00000123163
zgc:85936
zgc:85936
chr6_-_34838397 1.97 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr3_-_15679107 1.96 ENSDART00000080441
zgc:66443
zgc:66443
chr18_+_41561285 1.95 ENSDART00000169621
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr10_+_15255198 1.89 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr10_+_21434649 1.89 ENSDART00000193938
ENSDART00000064558
etf1b
eukaryotic translation termination factor 1b
chr1_-_23268569 1.88 ENSDART00000143948
rfc1
replication factor C (activator 1) 1
chr18_-_16924221 1.88 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr20_+_41801913 1.86 ENSDART00000139805
mcm9
minichromosome maintenance 9 homologous recombination repair factor
chr25_-_12824656 1.85 ENSDART00000171801
uba2
ubiquitin-like modifier activating enzyme 2
chr23_-_36449111 1.85 ENSDART00000110478
zgc:174906
zgc:174906
chr25_+_3326885 1.83 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr5_+_34549365 1.82 ENSDART00000009500
aif1l
allograft inflammatory factor 1-like
chr6_+_7533601 1.79 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr20_-_23439011 1.78 ENSDART00000022887
slc10a4
solute carrier family 10, member 4
chr5_+_34549845 1.77 ENSDART00000139317
aif1l
allograft inflammatory factor 1-like
chr5_-_32338866 1.77 ENSDART00000017956
ENSDART00000047670
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr20_+_44582318 1.76 ENSDART00000149000
ENSDART00000149775
ENSDART00000085416
atad2b
ATPase family, AAA domain containing 2B
chr23_+_17839187 1.75 ENSDART00000104647
prim1
DNA primase subunit 1
chr10_+_15255012 1.74 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr5_-_19014589 1.73 ENSDART00000002624
ranbp1
RAN binding protein 1
chr12_+_9499742 1.70 ENSDART00000044150
ENSDART00000136354
dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr20_-_9199721 1.69 ENSDART00000064140
ylpm1
YLP motif containing 1
chr19_-_44955710 1.69 ENSDART00000165246
CSMD3 (1 of many)
si:ch211-233f16.1
chr5_+_20453874 1.68 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr20_-_38827623 1.68 ENSDART00000153310
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr25_-_4482449 1.66 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr21_-_19916021 1.65 ENSDART00000065671
eri1
exoribonuclease 1
chr19_-_20403845 1.64 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr19_-_31007417 1.60 ENSDART00000048144
rbbp4
retinoblastoma binding protein 4
chr25_-_32363341 1.60 ENSDART00000153892
ENSDART00000114385
cep152
centrosomal protein 152
chr12_+_9499993 1.59 ENSDART00000135871
dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr1_-_20068155 1.59 ENSDART00000102993
mettl14
methyltransferase like 14
chr21_-_233282 1.59 ENSDART00000157684
bxdc2
brix domain containing 2
chr5_-_20491198 1.57 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr18_+_15271993 1.55 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr20_-_29633507 1.55 ENSDART00000040292
cpsf3
cleavage and polyadenylation specific factor 3
chr22_-_5822147 1.55 ENSDART00000011076
cers5
ceramide synthase 5
chr17_+_8799661 1.55 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr12_+_9183626 1.54 ENSDART00000020192
tubgcp2
tubulin, gamma complex associated protein 2
chr8_+_30112655 1.51 ENSDART00000099027
fancc
Fanconi anemia, complementation group C
chr6_+_32046202 1.50 ENSDART00000156552
si:dkey-148h10.5
si:dkey-148h10.5
chr14_-_30918662 1.49 ENSDART00000176631
si:ch211-126c2.4
si:ch211-126c2.4
chr25_+_186583 1.48 ENSDART00000161504
pclaf
PCNA clamp associated factor
chr17_+_4325693 1.44 ENSDART00000154264
mcm8
minichromosome maintenance 8 homologous recombination repair factor
chr8_-_12403077 1.43 ENSDART00000142150
phf19
PHD finger protein 19
chr9_+_29431763 1.42 ENSDART00000186095
ENSDART00000182640
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr13_-_36844945 1.42 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr20_+_43648369 1.42 ENSDART00000187930
ENSDART00000017269
parp1
poly (ADP-ribose) polymerase 1
chr1_+_14020445 1.41 ENSDART00000079716
hpf1
histone PARylation factor 1
chr15_+_44201056 1.40 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr21_-_19915757 1.40 ENSDART00000164317
eri1
exoribonuclease 1
chr3_+_19245804 1.39 ENSDART00000134514
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr10_+_33588715 1.36 ENSDART00000051198
mis18a
MIS18 kinetochore protein A
chr17_-_27266053 1.34 ENSDART00000110903
E2F2
si:ch211-160f23.5
chr8_+_20140321 1.34 ENSDART00000012120
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr18_+_18104235 1.33 ENSDART00000145342
cbln1
cerebellin 1 precursor
chr15_-_26538989 1.33 ENSDART00000032880
rpa1
replication protein A1
chr2_+_38055529 1.32 ENSDART00000145642
si:rp71-1g18.1
si:rp71-1g18.1
chr17_-_49407091 1.32 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr19_+_25465025 1.30 ENSDART00000018553
rpa3
replication protein A3
chr2_-_57941037 1.29 ENSDART00000131420
si:dkeyp-68b7.5
si:dkeyp-68b7.5
chr23_+_40410644 1.28 ENSDART00000056328
elovl4b
ELOVL fatty acid elongase 4b
chr3_-_45777226 1.28 ENSDART00000192849
h3f3b.1
H3 histone, family 3B.1
chr7_-_40657831 1.28 ENSDART00000084153
nom1
nucleolar protein with MIF4G domain 1
chr13_+_31402067 1.26 ENSDART00000019202
tdrd9
tudor domain containing 9
chr1_-_59216197 1.25 ENSDART00000062426
lpar2b
lysophosphatidic acid receptor 2b
chr5_+_69868911 1.25 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr20_+_21268795 1.24 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr21_+_26522571 1.24 ENSDART00000134617
adssl
adenylosuccinate synthase, like
chr10_+_4046448 1.22 ENSDART00000123086
ENSDART00000052268
pitpnb
phosphatidylinositol transfer protein, beta
chr9_+_21535885 1.22 ENSDART00000141408
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr4_-_15003854 1.21 ENSDART00000134701
ENSDART00000002401
klhdc10
kelch domain containing 10
chr23_+_24598910 1.16 ENSDART00000126510
ENSDART00000078796
kansl2
KAT8 regulatory NSL complex subunit 2
chr7_+_19851422 1.15 ENSDART00000142970
ENSDART00000190027
mus81
MUS81 structure-specific endonuclease subunit
chr20_+_46427984 1.15 ENSDART00000060706
ENSDART00000143858
rad51
RAD51 recombinase
chr12_+_13344896 1.15 ENSDART00000089017
rnasen
ribonuclease type III, nuclear
chr18_-_12858016 1.13 ENSDART00000130343
parp12a
poly (ADP-ribose) polymerase family, member 12a
chr5_-_42872712 1.12 ENSDART00000003947
flot2a
flotillin 2a
chr17_-_22573311 1.12 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exo1
exonuclease 1
chr6_-_33931696 1.10 ENSDART00000057290
prpf38a
pre-mRNA processing factor 38A
chr8_+_20415824 1.10 ENSDART00000009081
ENSDART00000145444
mob3a
MOB kinase activator 3A
chr14_+_46223458 1.07 ENSDART00000173428
cabp2b
calcium binding protein 2b
chr19_-_10214264 1.07 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr23_-_36305874 1.04 ENSDART00000147598
ENSDART00000146986
ENSDART00000086985
ENSDART00000133259
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr20_-_54075136 1.04 ENSDART00000074255
mgat2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr10_+_29849497 1.03 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr2_-_37134169 1.01 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr23_+_20518504 0.99 ENSDART00000114246
adnpb
activity-dependent neuroprotector homeobox b
chr12_+_17927871 0.99 ENSDART00000172062
trrap
transformation/transcription domain-associated protein
chr20_+_263056 0.96 ENSDART00000132669
tube1
tubulin, epsilon 1
chr24_-_41657005 0.95 ENSDART00000159109
CABZ01044099.1

chr2_+_8779164 0.95 ENSDART00000134308
zzz3
zinc finger, ZZ-type containing 3
chr8_-_24791060 0.95 ENSDART00000111617
rbm15
RNA binding motif protein 15
chr1_-_12126535 0.93 ENSDART00000164817
ENSDART00000015251
mttp
microsomal triglyceride transfer protein
chr6_+_9107063 0.93 ENSDART00000083820
vps16
vacuolar protein sorting protein 16
chr10_+_17681074 0.92 ENSDART00000057500
drg1
developmentally regulated GTP binding protein 1
chr21_-_23017478 0.92 ENSDART00000024309
rb1
retinoblastoma 1
chr7_-_44704910 0.91 ENSDART00000037850
dync1li2
dynein, cytoplasmic 1, light intermediate chain 2
chr9_+_28232522 0.91 ENSDART00000031761
fzd5
frizzled class receptor 5

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f2_e2f5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.9 GO:0034421 post-translational protein acetylation(GO:0034421)
3.8 37.6 GO:0044030 regulation of DNA methylation(GO:0044030)
3.0 32.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.9 8.8 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
2.9 20.5 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
2.4 17.0 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
2.4 19.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.3 29.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.9 5.6 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
1.8 24.5 GO:0006270 DNA replication initiation(GO:0006270)
1.6 6.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.4 4.3 GO:0006272 leading strand elongation(GO:0006272)
1.3 3.8 GO:0034969 histone arginine methylation(GO:0034969)
1.2 2.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.1 3.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
1.1 5.3 GO:0043111 replication fork arrest(GO:0043111)
1.1 4.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.0 3.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.9 2.7 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.9 7.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.8 4.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.8 29.7 GO:0048538 thymus development(GO:0048538)
0.6 3.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 4.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.6 1.7 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.5 3.3 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.5 3.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5 2.9 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 1.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 3.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 2.5 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 8.4 GO:0030261 chromosome condensation(GO:0030261)
0.4 1.6 GO:0098535 de novo centriole assembly(GO:0098535)
0.4 1.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 3.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.4 2.1 GO:0040016 embryonic cleavage(GO:0040016)
0.4 3.9 GO:0030719 P granule organization(GO:0030719)
0.3 1.7 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.3 1.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.3 1.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 1.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.3 5.6 GO:0060969 negative regulation of gene silencing(GO:0060969)
0.3 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 3.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.3 1.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.7 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 3.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.2 3.8 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.2 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704) cortisol metabolic process(GO:0034650)
0.2 4.4 GO:0031297 replication fork processing(GO:0031297)
0.2 1.8 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.2 2.4 GO:0006298 mismatch repair(GO:0006298)
0.2 0.9 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 2.9 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 0.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 1.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 0.8 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 3.3 GO:0032392 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.2 0.8 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) immunoglobulin V(D)J recombination(GO:0033152) T cell receptor V(D)J recombination(GO:0033153)
0.2 4.5 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.2 0.7 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 3.6 GO:0097178 ruffle assembly(GO:0097178)
0.2 2.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.4 GO:0021634 optic nerve formation(GO:0021634)
0.2 1.0 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 4.8 GO:0016925 protein sumoylation(GO:0016925)
0.2 0.7 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2 1.7 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 5.0 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.1 2.1 GO:0006265 DNA topological change(GO:0006265)
0.1 0.4 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 1.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 3.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.9 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 1.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.9 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.5 GO:0002312 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.1 1.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 2.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.6 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 1.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.6 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 2.4 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.1 1.5 GO:0007020 microtubule nucleation(GO:0007020)
0.1 6.8 GO:0016125 sterol metabolic process(GO:0016125)
0.1 1.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 1.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 3.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.3 GO:0014004 microglia differentiation(GO:0014004)
0.0 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.0 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 1.9 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 5.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 1.2 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 3.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.5 GO:0072576 liver morphogenesis(GO:0072576)
0.0 3.3 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 2.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.6 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.0 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 0.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 3.2 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.8 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.4 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 16.9 GO:0031261 DNA replication preinitiation complex(GO:0031261)
2.1 23.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.8 33.2 GO:0042555 MCM complex(GO:0042555)
1.3 6.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.3 3.9 GO:0033391 chromatoid body(GO:0033391)
1.2 3.7 GO:0098536 deuterosome(GO:0098536)
1.1 4.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.0 4.2 GO:0033186 CAF-1 complex(GO:0033186)
1.0 3.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.0 4.9 GO:0031298 replication fork protection complex(GO:0031298)
0.8 2.5 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.5 2.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 1.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.5 1.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 5.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 1.6 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 5.4 GO:0000792 heterochromatin(GO:0000792)
0.4 1.9 GO:0018444 translation release factor complex(GO:0018444)
0.3 2.8 GO:0000796 condensin complex(GO:0000796)
0.3 1.1 GO:0016600 flotillin complex(GO:0016600)
0.3 3.6 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.2 0.7 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.8 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 2.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 0.8 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 7.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 1.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.9 GO:0033263 CORVET complex(GO:0033263)
0.2 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 0.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 1.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.6 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.7 GO:0015030 Cajal body(GO:0015030)
0.1 1.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.0 GO:0000124 SAGA complex(GO:0000124)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 26.1 GO:0005730 nucleolus(GO:0005730)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 2.6 GO:0016605 PML body(GO:0016605)
0.1 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.1 17.7 GO:0000785 chromatin(GO:0000785)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.4 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 4.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 43.5 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.8 GO:0005819 spindle(GO:0005819)
0.0 1.4 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 112.1 GO:0005634 nucleus(GO:0005634)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 9.7 GO:0042175 endoplasmic reticulum membrane(GO:0005789) nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 3.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 27.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.6 64.1 GO:0003688 DNA replication origin binding(GO:0003688)
2.0 14.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.8 7.2 GO:0070182 DNA polymerase binding(GO:0070182)
1.4 18.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.3 3.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.1 5.6 GO:0009374 biotin binding(GO:0009374)
1.1 4.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.1 4.3 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
1.0 3.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.9 3.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.6 4.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.6 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 3.7 GO:0070330 aromatase activity(GO:0070330)
0.6 4.8 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.6 9.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.6 2.9 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.6 4.0 GO:0035173 histone kinase activity(GO:0035173)
0.6 1.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.5 1.6 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.5 3.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5 1.9 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.4 2.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 2.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 2.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.4 1.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.4 0.7 GO:0000217 DNA secondary structure binding(GO:0000217)
0.4 20.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.3 1.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 2.5 GO:0008494 translation activator activity(GO:0008494)
0.3 2.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 3.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.3 1.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.9 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.2 0.9 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.2 1.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 2.7 GO:0031386 protein tag(GO:0031386)
0.2 4.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.1 GO:0003917 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.1 5.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.3 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 13.7 GO:0016407 acetyltransferase activity(GO:0016407)
0.1 1.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.6 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.3 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.1 2.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.8 GO:0004067 asparaginase activity(GO:0004067)
0.1 3.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 2.1 GO:0017069 snRNA binding(GO:0017069)
0.1 2.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 4.3 GO:0031072 heat shock protein binding(GO:0031072)
0.1 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 10.3 GO:0042393 histone binding(GO:0042393)
0.1 1.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.3 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 3.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 3.8 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.4 GO:0004519 endonuclease activity(GO:0004519)
0.0 2.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 3.8 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 4.1 GO:0051015 actin filament binding(GO:0051015)
0.0 3.8 GO:0016887 ATPase activity(GO:0016887)
0.0 9.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.0 77.9 PID E2F PATHWAY E2F transcription factor network
0.4 12.0 PID AURORA B PATHWAY Aurora B signaling
0.3 14.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 13.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 6.6 PID ATR PATHWAY ATR signaling pathway
0.2 3.6 PID REELIN PATHWAY Reelin signaling pathway
0.2 4.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 3.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 6.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.3 PID BARD1 PATHWAY BARD1 signaling events
0.1 5.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 3.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 2.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 42.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
2.8 42.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
2.2 44.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.9 17.0 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.8 8.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.6 8.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.4 3.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 2.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 2.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 1.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 4.0 REACTOME KINESINS Genes involved in Kinesins
0.2 2.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 3.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 3.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 3.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.9 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.6 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 3.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.8 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.1 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 1.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis