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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for elf2a+elf2b

Z-value: 3.05

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Transcription factors associated with elf2a+elf2b

Gene Symbol Gene ID Gene Info
elf2a
ENSDARG00000019459 E74-like factor 2a (ets domain transcription factor)
elf2b
ENSDARG00000079626 E74-like factor 2b (ets domain transcription factor)
elf2b
ENSDARG00000117064 E74-like factor 2b (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf2bdr11_v1_chr1_-_13989643_139896430.827.5e-24Click!
elf2adr11_v1_chr14_-_46070802_460708020.802.1e-22Click!

Activity profile of elf2a+elf2b motif

Sorted Z-values of elf2a+elf2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_6982499 22.52 ENSDART00000101525
si:dkey-266m15.6
si:dkey-266m15.6
chr1_-_45177373 22.46 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr4_-_76383223 19.55 ENSDART00000161866
ENSDART00000168456
ENSDART00000174287
ENSDART00000174048
zgc:123107
zgc:123107
chr15_+_42573909 19.51 ENSDART00000181801
CLDN8 (1 of many)
zgc:110333
chr16_-_45001842 18.53 ENSDART00000037797
sult2st3
sulfotransferase family 2, cytosolic sulfotransferase 3
chr22_+_5478353 17.75 ENSDART00000160596
tppp
tubulin polymerization promoting protein
chr1_-_26026956 17.18 ENSDART00000102346
si:ch211-145b13.6
si:ch211-145b13.6
chr14_-_33277743 15.85 ENSDART00000048130
stard14
START domain containing 14
chr24_-_26328721 13.96 ENSDART00000125468
apodb
apolipoprotein Db
chr15_-_2652640 13.95 ENSDART00000146094
cldnf
claudin f
chr11_-_3865472 13.64 ENSDART00000161426
gata2a
GATA binding protein 2a
chr2_+_49457626 13.55 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr19_+_43359075 13.00 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr3_+_32492467 12.95 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr1_-_26027327 12.93 ENSDART00000171292
ENSDART00000170878
si:ch211-145b13.6
si:ch211-145b13.6
chr14_+_20911310 12.62 ENSDART00000160318
lygl2
lysozyme g-like 2
chr14_-_33278084 12.61 ENSDART00000132850
stard14
START domain containing 14
chr3_+_32416948 12.42 ENSDART00000157324
ENSDART00000154267
ENSDART00000186094
ENSDART00000155860
ENSDART00000156986
prrg2
proline rich Gla (G-carboxyglutamic acid) 2
chr12_+_22576404 12.22 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr16_+_17715243 12.21 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr15_+_36445350 11.73 ENSDART00000154552
si:dkey-262k9.2
si:dkey-262k9.2
chr1_-_37383539 11.48 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr4_+_18843015 11.43 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
bik
BCL2 interacting killer
chr20_+_46040666 11.37 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr2_+_20967673 11.34 ENSDART00000057174
arpc5a
actin related protein 2/3 complex, subunit 5A
chr21_+_30794351 11.25 ENSDART00000139486
zgc:158225
zgc:158225
chr15_+_3808996 11.24 ENSDART00000110227
RNF14 (1 of many)
ring finger protein 14
chr5_+_27404946 11.20 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr14_-_32876280 11.14 ENSDART00000173168
si:rp71-46j2.7
si:rp71-46j2.7
chr3_-_32337653 11.07 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr17_-_26935339 11.05 ENSDART00000139946
nipal3
NIPA-like domain containing 3
chr3_-_27647845 11.02 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr13_-_36391496 10.98 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr17_-_8886735 10.67 ENSDART00000121997
nkl.3
NK-lysin tandem duplicate 3
chr3_-_27646070 10.61 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
si:ch211-157c3.4
chr22_+_21549419 10.60 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr11_-_11890001 10.60 ENSDART00000081544
wipf2a
WAS/WASL interacting protein family, member 2a
chr3_+_53240562 10.56 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr3_-_39488482 10.48 ENSDART00000135192
zgc:100868
zgc:100868
chr16_-_31976269 10.25 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr8_-_21052371 10.22 ENSDART00000136561
si:dkeyp-82a1.6
si:dkeyp-82a1.6
chr16_+_11818126 10.22 ENSDART00000145727
cxcr3.2
chemokine (C-X-C motif) receptor 3, tandem duplicate 2
chr5_+_56026031 10.14 ENSDART00000050970
fzd9a
frizzled class receptor 9a
chr6_-_39313027 10.09 ENSDART00000012644
krt4
keratin 4
chr1_+_56180416 10.00 ENSDART00000089358
crb3b
crumbs homolog 3b
chr3_+_5331428 9.99 ENSDART00000156561
si:ch73-106l15.4
si:ch73-106l15.4
chr5_-_12587053 9.88 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr5_-_37116265 9.83 ENSDART00000057613
il13ra2
interleukin 13 receptor, alpha 2
chr1_-_37383741 9.82 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr6_+_18142623 9.79 ENSDART00000169431
ENSDART00000158841
si:dkey-237i9.8
si:dkey-237i9.8
chr7_-_25133783 9.61 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr2_+_49457449 9.49 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr19_-_11015238 9.46 ENSDART00000010997
tpm3
tropomyosin 3
chr4_-_18954001 9.44 ENSDART00000144814
si:dkey-31f5.8
si:dkey-31f5.8
chr22_-_26353916 9.41 ENSDART00000077958
capn2b
calpain 2, (m/II) large subunit b
chr9_-_3400727 9.38 ENSDART00000183979
ENSDART00000111386
dlx2a
distal-less homeobox 2a
chr20_-_5369105 9.24 ENSDART00000114316
sptlc2b
serine palmitoyltransferase, long chain base subunit 2b
chr4_+_22680442 9.23 ENSDART00000036531
gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr24_-_31306724 9.17 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr12_-_22355430 9.07 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
nsfb
N-ethylmaleimide-sensitive factor b
chr7_+_71764883 9.06 ENSDART00000166865
myl12.1
myosin, light chain 12, genome duplicate 1
chr16_+_35918463 8.97 ENSDART00000160608
sh3d21
SH3 domain containing 21
chr23_+_18779043 8.97 ENSDART00000158267
emp3b
epithelial membrane protein 3b
chr14_-_34059681 8.83 ENSDART00000003993
itk
IL2 inducible T cell kinase
chr11_+_37265692 8.83 ENSDART00000184691
il17rc
interleukin 17 receptor C
chr8_+_3426522 8.72 ENSDART00000159466
CU929199.1

chr24_-_11076400 8.72 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr22_+_5687615 8.61 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr17_+_34805897 8.56 ENSDART00000137090
ENSDART00000077626
id2a
inhibitor of DNA binding 2a
chr5_-_42272517 8.52 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr20_-_40717900 8.44 ENSDART00000181663
cx43
connexin 43
chr17_-_8862424 8.41 ENSDART00000064633
nkl.4
NK-lysin tandem duplicate 4
chr17_-_30666037 8.39 ENSDART00000156509
alkal2b
ALK and LTK ligand 2b
chr2_+_19163965 8.37 ENSDART00000166073
elovl1a
ELOVL fatty acid elongase 1a
chr6_-_49063085 8.33 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr14_+_31865099 8.28 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr18_-_35459996 8.24 ENSDART00000141023
itpkcb
inositol-trisphosphate 3-kinase Cb
chr8_+_32406885 8.24 ENSDART00000167600
epgn
epithelial mitogen homolog (mouse)
chr18_-_17485419 8.19 ENSDART00000018764
foxl1
forkhead box L1
chr3_+_34846201 8.19 ENSDART00000055263
itga3a
integrin, alpha 3a
chr16_+_7242610 8.17 ENSDART00000081477
sri
sorcin
chr6_+_34038963 8.09 ENSDART00000057732
ENSDART00000192496
ap1m3
adaptor-related protein complex 1, mu 3 subunit
chr1_-_50247 8.00 ENSDART00000168428
ildr1a
immunoglobulin-like domain containing receptor 1a
chr6_-_21616659 7.92 ENSDART00000074256
ppp1r12c
protein phosphatase 1, regulatory subunit 12C
chr14_+_31865324 7.91 ENSDART00000039880
tm9sf5
transmembrane 9 superfamily protein member 5
chr5_+_4366431 7.87 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr21_-_8085635 7.85 ENSDART00000082790
si:dkey-163m14.2
si:dkey-163m14.2
chr12_-_7234915 7.75 ENSDART00000048866
ipmkb
inositol polyphosphate multikinase b
chr22_-_11833317 7.74 ENSDART00000125423
ENSDART00000000192
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr22_+_35068046 7.73 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr17_+_50261603 7.73 ENSDART00000154503
ENSDART00000154467
syncripl
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr23_+_36653376 7.73 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr23_+_10146542 7.67 ENSDART00000048073
zgc:171775
zgc:171775
chr12_-_33789006 7.66 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr19_-_9522548 7.64 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr21_+_22738939 7.60 ENSDART00000151342
ENSDART00000079145
arhgap42a
Rho GTPase activating protein 42a
chr25_+_33202294 7.56 ENSDART00000131098
TPM1 (1 of many)
zgc:171719
chr14_-_22015232 7.55 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr2_+_6243144 7.52 ENSDART00000058258
gng5
guanine nucleotide binding protein (G protein), gamma 5
chr21_+_22985078 7.47 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr6_-_8489810 7.45 ENSDART00000124643
rasal3
RAS protein activator like 3
chr25_-_22191983 7.40 ENSDART00000191181
pkp3a
plakophilin 3a
chr1_-_44581937 7.38 ENSDART00000009858
tmx2b
thioredoxin-related transmembrane protein 2b
chr23_-_5818992 7.38 ENSDART00000148730
csrp1a
cysteine and glycine-rich protein 1a
chr3_+_26814030 7.33 ENSDART00000180128
socs1a
suppressor of cytokine signaling 1a
chr17_-_25382367 7.30 ENSDART00000162306
ENSDART00000165282
lck
LCK proto-oncogene, Src family tyrosine kinase
chr16_-_21038015 7.29 ENSDART00000059239
snx10b
sorting nexin 10b
chr5_+_32141790 7.26 ENSDART00000041504
tescb
tescalcin b
chr13_-_25484659 7.22 ENSDART00000135321
ENSDART00000022799
tial1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr21_+_38638979 7.17 ENSDART00000143373
rbmx2
RNA binding motif protein, X-linked 2
chr6_+_23810529 7.14 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr24_+_25069609 7.14 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr1_-_25486471 7.13 ENSDART00000134200
ENSDART00000141892
ENSDART00000102501
arfip1
ADP-ribosylation factor interacting protein 1 (arfaptin 1)
chr19_-_29853402 7.11 ENSDART00000024292
ENSDART00000188508
txlna
taxilin alpha
chr8_+_36554816 7.04 ENSDART00000126687
sf3a1
splicing factor 3a, subunit 1
chr16_+_38277339 6.99 ENSDART00000085143
bnipl
BCL2 interacting protein like
chr1_+_54737353 6.99 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr25_+_7784582 6.94 ENSDART00000155016
dgkzb
diacylglycerol kinase, zeta b
chr23_-_5719453 6.93 ENSDART00000033093
lad1
ladinin
chr8_+_25359394 6.93 ENSDART00000111248
si:dkey-183p4.10
si:dkey-183p4.10
chr3_+_36424055 6.87 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr16_-_25233515 6.76 ENSDART00000058943
zgc:110182
zgc:110182
chr15_-_28904371 6.74 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr5_+_15203421 6.69 ENSDART00000040826
tbx1
T-box 1
chr23_-_5101847 6.69 ENSDART00000122240
etv7
ets variant 7
chr21_-_43328056 6.68 ENSDART00000114955
sowahaa
sosondowah ankyrin repeat domain family member Aa
chr11_-_36263886 6.67 ENSDART00000140397
nfya
nuclear transcription factor Y, alpha
chr1_-_45146834 6.64 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr10_+_8875195 6.63 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr19_-_27006764 6.62 ENSDART00000089540
sacm1la
SAC1 like phosphatidylinositide phosphatase a
chr14_-_2602445 6.61 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr9_-_25989989 6.59 ENSDART00000090052
arhgap15
Rho GTPase activating protein 15
chr5_-_37959874 6.57 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr6_+_49095646 6.51 ENSDART00000103385
slc25a55a
solute carrier family 25, member 55a
chr9_-_42484444 6.51 ENSDART00000048320
ENSDART00000047653
tfpia
tissue factor pathway inhibitor a
chr4_-_16354292 6.51 ENSDART00000139919
lum
lumican
chr13_+_24402406 6.48 ENSDART00000043002
rab1ab
RAB1A, member RAS oncogene family b
chr25_+_753364 6.48 ENSDART00000183804
TWF1 (1 of many)
twinfilin actin binding protein 1
chr9_-_48077034 6.45 ENSDART00000099803
arpc2
actin related protein 2/3 complex, subunit 2
chr25_+_34014523 6.45 ENSDART00000182856
anxa2a
annexin A2a
chr1_+_25650917 6.40 ENSDART00000054235
plrg1
pleiotropic regulator 1
chr20_+_26916639 6.40 ENSDART00000077787
serpinb1l2
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 2
chr4_-_12323228 6.38 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr20_-_32045057 6.38 ENSDART00000152970
ENSDART00000034248
rab32a
RAB32a, member RAS oncogene family
chr20_+_37844035 6.38 ENSDART00000041397
flvcr1
feline leukemia virus subgroup C cellular receptor 1
chr7_+_74141297 6.37 ENSDART00000164992
rbpms
RNA binding protein with multiple splicing
chr16_-_26232411 6.37 ENSDART00000139355
arhgef1b
Rho guanine nucleotide exchange factor (GEF) 1b
chr20_-_26937453 6.35 ENSDART00000139756
ftr97
finTRIM family, member 97
chr3_+_3598555 6.34 ENSDART00000191152
CR589947.3

chr14_+_26224541 6.34 ENSDART00000128971
gm2a
GM2 ganglioside activator
chr23_+_43638982 6.34 ENSDART00000168646
slc10a7
solute carrier family 10, member 7
chr23_+_20669149 6.33 ENSDART00000138936
arhgef3l
Rho guanine nucleotide exchange factor (GEF) 3, like
chr16_+_13427967 6.29 ENSDART00000038196
zgc:101640
zgc:101640
chr9_+_426392 6.28 ENSDART00000172515
bzw1b
basic leucine zipper and W2 domains 1b
chr1_+_38142715 6.27 ENSDART00000079928
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr16_+_3982590 6.20 ENSDART00000149295
zc3h12a
zinc finger CCCH-type containing 12A
chr24_-_8409641 6.17 ENSDART00000149662
ENSDART00000149025
slc35b3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr5_-_30984010 6.16 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr17_-_2039511 6.16 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr20_+_41021054 6.15 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr10_-_108952 6.14 ENSDART00000127228
ttc3
tetratricopeptide repeat domain 3
chr21_+_45626136 6.14 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr16_+_33144306 6.13 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr11_-_25853212 6.13 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr19_+_10331325 6.11 ENSDART00000143930
tmem238a
transmembrane protein 238a
chr5_+_23024033 6.10 ENSDART00000171199
chmp1b
chromatin modifying protein 1B
chr15_+_7057050 6.06 ENSDART00000061828
foxl2a
forkhead box L2a
chr18_+_44532370 6.05 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr3_+_43825785 6.03 ENSDART00000157619
litaf
lipopolysaccharide-induced TNF factor
chr24_-_6078222 6.01 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr21_+_11778823 6.00 ENSDART00000031786
glrx
glutaredoxin (thioltransferase)
chr1_-_18848955 5.99 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr17_+_25397070 5.97 ENSDART00000164254
zgc:154055
zgc:154055
chr8_-_4694458 5.97 ENSDART00000019828
zgc:63587
zgc:63587
chr18_+_48423973 5.96 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr9_-_33081781 5.95 ENSDART00000165748
zgc:172053
zgc:172053
chr4_+_12966640 5.95 ENSDART00000113357
vhll
von Hippel-Lindau tumor suppressor like
chr3_+_36616713 5.93 ENSDART00000158284
pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr17_+_45395846 5.91 ENSDART00000058793
nenf
neudesin neurotrophic factor
chr19_-_325584 5.90 ENSDART00000134266
gpd1c
glycerol-3-phosphate dehydrogenase 1c
chr18_+_27001115 5.90 ENSDART00000133547
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr23_+_26009266 5.90 ENSDART00000054025
si:dkey-78k11.9
si:dkey-78k11.9
chr25_-_16724913 5.90 ENSDART00000157075
galnt8a.2
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 2
chr21_-_15200556 5.90 ENSDART00000141809
sfswap
splicing factor SWAP
chr18_+_18982077 5.89 ENSDART00000006300
hacd3
3-hydroxyacyl-CoA dehydratase 3
chr24_-_25004553 5.88 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr1_-_38170997 5.87 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr14_+_52440161 5.85 ENSDART00000168437
b4galt1l
DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like
chr3_+_46479705 5.84 ENSDART00000181564
tyk2
tyrosine kinase 2
chr10_+_5234327 5.83 ENSDART00000133927
ENSDART00000063120
sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr16_+_26680508 5.82 ENSDART00000142215
ENSDART00000159064
virma
vir like m6A methyltransferase associated
chr5_+_37087583 5.81 ENSDART00000049900
tagln2
transgelin 2
chr11_+_43740949 5.80 ENSDART00000189296
CU862021.1

chr13_+_1155536 5.79 ENSDART00000148356
perp
PERP, TP53 apoptosis effector
chr17_-_30635298 5.79 ENSDART00000155478
sh3yl1
SH3 and SYLF domain containing 1
chr11_-_21404358 5.74 ENSDART00000129062
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr11_-_13126505 5.74 ENSDART00000158377
elovl1b
ELOVL fatty acid elongase 1b
chr10_+_27096043 5.73 ENSDART00000064107
ENSDART00000159751
cxadr
CXADR, Ig-like cell adhesion molecule
chr15_-_28085480 5.72 ENSDART00000060304
ENSDART00000192239
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr9_-_4075620 5.72 ENSDART00000046903
mylka
myosin, light chain kinase a

Network of associatons between targets according to the STRING database.

First level regulatory network of elf2a+elf2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0002369 T cell cytokine production(GO:0002369)
4.5 13.6 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
4.2 12.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
3.6 3.6 GO:0051125 regulation of actin nucleation(GO:0051125)
3.4 10.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
3.3 19.5 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
3.1 3.1 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
3.0 12.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
2.8 30.9 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
2.8 11.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.6 13.1 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
2.3 9.1 GO:0048211 Golgi vesicle docking(GO:0048211)
2.2 6.7 GO:0003156 regulation of organ formation(GO:0003156)
2.0 14.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
2.0 8.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
2.0 6.1 GO:0048496 maintenance of organ identity(GO:0048496)
2.0 5.9 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.9 7.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
1.8 19.6 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
1.7 5.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.7 6.8 GO:0051645 Golgi localization(GO:0051645)
1.6 4.9 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
1.6 6.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.6 6.4 GO:0097037 heme export(GO:0097037)
1.6 6.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.6 4.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.6 4.7 GO:0034421 post-translational protein acetylation(GO:0034421)
1.5 4.6 GO:0070914 UV-damage excision repair(GO:0070914)
1.5 5.9 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
1.5 4.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.5 4.4 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
1.4 5.8 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
1.4 8.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
1.4 4.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.4 2.8 GO:0033337 dorsal fin development(GO:0033337)
1.4 5.6 GO:0046324 regulation of glucose import(GO:0046324)
1.4 4.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
1.4 4.2 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
1.4 7.0 GO:0007220 Notch receptor processing(GO:0007220)
1.4 8.4 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
1.3 4.0 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
1.3 3.9 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.3 2.6 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.2 7.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.2 41.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
1.2 3.6 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.2 3.6 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
1.2 3.5 GO:0006089 lactate metabolic process(GO:0006089)
1.2 19.6 GO:0015693 magnesium ion transport(GO:0015693)
1.1 3.4 GO:1905072 cardiac jelly development(GO:1905072)
1.1 4.6 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
1.1 7.9 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
1.1 3.3 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
1.1 20.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.1 3.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.1 5.4 GO:0051639 actin filament network formation(GO:0051639)
1.1 4.4 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.1 3.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
1.1 9.5 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
1.0 4.2 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
1.0 4.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.0 7.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.0 3.0 GO:0060912 cardiac cell fate specification(GO:0060912)
1.0 2.0 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
1.0 3.0 GO:0000390 spliceosomal complex disassembly(GO:0000390)
1.0 5.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.0 4.9 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.0 4.9 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
1.0 7.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.0 3.9 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.9 3.7 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.9 23.1 GO:0030497 fatty acid elongation(GO:0030497)
0.9 5.5 GO:0010269 response to selenium ion(GO:0010269)
0.9 6.4 GO:0060036 notochord cell vacuolation(GO:0060036)
0.9 2.7 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.9 6.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.9 9.6 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.9 22.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.9 3.4 GO:0010259 multicellular organism aging(GO:0010259)
0.9 5.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.9 2.6 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.9 4.3 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.9 15.4 GO:0051764 actin crosslink formation(GO:0051764)
0.8 16.9 GO:0007032 endosome organization(GO:0007032)
0.8 3.4 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.8 9.2 GO:0045453 bone resorption(GO:0045453)
0.8 4.9 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.8 4.0 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.8 3.2 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.8 6.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.8 4.0 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.8 1.6 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.8 3.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.8 4.7 GO:0032447 protein urmylation(GO:0032447)
0.8 15.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.8 3.8 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.7 30.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.7 3.6 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.7 5.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.7 3.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.7 16.4 GO:1901654 response to ketone(GO:1901654)
0.7 2.8 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.7 2.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.7 4.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.7 3.4 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.7 4.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.7 4.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.7 6.5 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.6 15.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.6 1.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6 2.6 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.6 1.9 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.6 3.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.6 3.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.6 1.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.6 4.8 GO:0042554 superoxide anion generation(GO:0042554)
0.6 2.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.6 13.6 GO:0007568 aging(GO:0007568)
0.6 1.8 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.6 2.3 GO:0006740 NADPH regeneration(GO:0006740)
0.6 15.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.6 1.7 GO:0060031 mediolateral intercalation(GO:0060031)
0.6 8.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.6 5.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.6 2.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.6 2.3 GO:0048618 embryonic digestive tract morphogenesis(GO:0048557) post-embryonic foregut morphogenesis(GO:0048618) adenohypophysis morphogenesis(GO:0048855)
0.6 1.7 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.6 3.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6 8.3 GO:0007398 ectoderm development(GO:0007398)
0.5 1.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.5 12.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.5 4.3 GO:0009791 post-embryonic development(GO:0009791)
0.5 1.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.5 3.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.5 11.1 GO:0048246 macrophage chemotaxis(GO:0048246)
0.5 19.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.5 5.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.5 6.0 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.5 4.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.5 7.9 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.5 6.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.5 3.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.5 2.4 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.5 2.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.5 8.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.5 6.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.5 4.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.5 1.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.5 3.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.5 4.6 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.5 4.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.5 3.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 4.9 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 2.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.4 4.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.4 2.2 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.4 3.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.4 4.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.4 10.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.4 1.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 11.7 GO:0090148 membrane fission(GO:0090148)
0.4 3.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.4 2.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 11.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.4 1.7 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.4 1.3 GO:0035046 pronuclear migration(GO:0035046)
0.4 3.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.4 1.7 GO:0071922 regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922)
0.4 3.3 GO:0036372 opsin transport(GO:0036372)
0.4 4.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.4 10.1 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.4 2.0 GO:0001839 neural plate morphogenesis(GO:0001839)
0.4 13.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.4 1.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.4 3.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 3.2 GO:0051013 microtubule severing(GO:0051013)
0.4 3.2 GO:0044211 CTP salvage(GO:0044211)
0.4 2.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 2.3 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.4 1.9 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.4 1.5 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.4 1.1 GO:0009264 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.4 1.9 GO:0060876 semicircular canal formation(GO:0060876)
0.4 8.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 2.2 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4 2.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 11.0 GO:0030199 collagen fibril organization(GO:0030199)
0.4 4.8 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.4 5.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.4 1.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.4 3.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.4 18.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.4 2.5 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.4 2.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.4 8.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.4 1.1 GO:0019348 dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.4 8.1 GO:0006491 N-glycan processing(GO:0006491)
0.3 6.9 GO:0030183 B cell differentiation(GO:0030183)
0.3 5.5 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 7.2 GO:0006825 copper ion transport(GO:0006825)
0.3 2.4 GO:0045619 regulation of lymphocyte differentiation(GO:0045619)
0.3 2.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.3 2.0 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.3 1.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.3 5.7 GO:0042574 retinal metabolic process(GO:0042574)
0.3 22.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 5.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 2.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 1.6 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 3.6 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.3 1.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.3 1.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 88.2 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.3 2.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.3 4.5 GO:0016926 protein desumoylation(GO:0016926)
0.3 15.5 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.3 8.1 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.3 1.9 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.3 1.9 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.3 6.7 GO:0042098 T cell proliferation(GO:0042098) regulation of T cell proliferation(GO:0042129)
0.3 1.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.3 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.3 4.7 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.3 26.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.3 1.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 0.9 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 9.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.3 8.7 GO:0048264 determination of ventral identity(GO:0048264)
0.3 2.1 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.3 6.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.3 9.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 6.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 1.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 4.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.3 13.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3 2.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 25.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.3 11.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.3 2.8 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 2.5 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.3 3.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 6.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.3 4.4 GO:0048844 artery morphogenesis(GO:0048844)
0.3 3.8 GO:0019985 translesion synthesis(GO:0019985)
0.3 2.4 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 12.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.3 0.3 GO:0042726 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.3 0.8 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.3 2.9 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.3 2.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.3 4.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 5.5 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.3 4.5 GO:0010737 protein kinase A signaling(GO:0010737)
0.3 1.0 GO:0061011 gall bladder development(GO:0061010) hepatic duct development(GO:0061011)
0.3 0.5 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.3 16.0 GO:0051607 defense response to virus(GO:0051607)
0.3 2.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.3 10.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 3.3 GO:0014812 muscle cell migration(GO:0014812)
0.3 0.8 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 11.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 5.7 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.2 4.9 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.2 1.7 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.2 3.2 GO:0042026 protein refolding(GO:0042026)
0.2 1.2 GO:0016233 telomere capping(GO:0016233)
0.2 2.2 GO:1901998 toxin transport(GO:1901998)
0.2 1.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 5.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 4.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.2 3.3 GO:0034661 ncRNA catabolic process(GO:0034661)
0.2 6.6 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.2 8.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.9 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.2 17.2 GO:0030048 actin filament-based movement(GO:0030048)
0.2 6.2 GO:0016925 protein sumoylation(GO:0016925)
0.2 2.5 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 5.0 GO:0007520 myoblast fusion(GO:0007520)
0.2 6.3 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.2 0.7 GO:0070126 mitochondrial translational termination(GO:0070126)
0.2 1.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 8.7 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.2 2.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 1.5 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 3.0 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.2 5.7 GO:0009395 phospholipid catabolic process(GO:0009395)
0.2 5.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 1.7 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 3.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 4.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.2 4.0 GO:0008643 carbohydrate transport(GO:0008643)
0.2 12.3 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.2 2.6 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.2 1.4 GO:0010574 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 3.3 GO:0045010 actin nucleation(GO:0045010)
0.2 9.4 GO:0006986 response to unfolded protein(GO:0006986)
0.2 1.7 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 6.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.2 9.5 GO:0030336 negative regulation of cell migration(GO:0030336)
0.2 7.5 GO:0006402 mRNA catabolic process(GO:0006402)
0.2 4.8 GO:1903311 regulation of mRNA metabolic process(GO:1903311)
0.2 1.6 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 2.0 GO:0006270 DNA replication initiation(GO:0006270)
0.2 8.7 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.2 6.0 GO:0048278 vesicle docking(GO:0048278)
0.2 13.2 GO:0007043 cell-cell junction assembly(GO:0007043)
0.2 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.2 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.2 0.7 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.2 1.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 4.4 GO:0009636 response to toxic substance(GO:0009636)
0.2 1.7 GO:0051601 exocyst localization(GO:0051601)
0.2 4.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.2 4.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 4.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 15.8 GO:0008380 RNA splicing(GO:0008380)
0.2 1.6 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.2 3.9 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.2 3.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 0.3 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.2 6.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 14.2 GO:0042246 tissue regeneration(GO:0042246)
0.2 7.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.2 3.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2 20.7 GO:0006338 chromatin remodeling(GO:0006338)
0.1 4.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 5.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 16.5 GO:0008544 epidermis development(GO:0008544)
0.1 3.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.9 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 1.0 GO:0009188 ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.1 4.7 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.9 GO:1905145 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.8 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 3.6 GO:0030098 lymphocyte differentiation(GO:0030098)
0.1 3.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 2.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 4.7 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 20.7 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1 2.8 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135)
0.1 1.7 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 5.7 GO:0030282 bone mineralization(GO:0030282)
0.1 2.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 4.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 1.0 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 2.8 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 3.4 GO:0043542 endothelial cell migration(GO:0043542)
0.1 8.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 1.6 GO:0034508 centromere complex assembly(GO:0034508)
0.1 1.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 12.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.7 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) regulation of oligodendrocyte differentiation(GO:0048713) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 3.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.6 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.4 GO:1904018 positive regulation of vasculature development(GO:1904018)
0.1 1.6 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.1 1.9 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 1.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 4.6 GO:1902275 regulation of chromatin organization(GO:1902275)
0.1 0.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 1.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 2.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 3.7 GO:0008360 regulation of cell shape(GO:0008360)
0.1 3.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 22.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 0.5 GO:0031116 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.1 6.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 1.7 GO:0033260 nuclear DNA replication(GO:0033260)
0.1 6.9 GO:0016236 macroautophagy(GO:0016236)
0.1 3.8 GO:0010469 regulation of receptor activity(GO:0010469)
0.1 4.7 GO:0007416 synapse assembly(GO:0007416)
0.1 4.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.1 1.1 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.1 1.7 GO:0036269 swimming behavior(GO:0036269)
0.1 1.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.4 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 1.0 GO:0070085 glycosylation(GO:0070085)
0.1 2.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 2.2 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 0.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.1 GO:0051055 negative regulation of lipid biosynthetic process(GO:0051055)
0.1 10.6 GO:0006869 lipid transport(GO:0006869)
0.1 0.8 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 3.7 GO:0016573 histone acetylation(GO:0016573)
0.1 1.0 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 5.1 GO:0006302 double-strand break repair(GO:0006302)
0.0 1.5 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 1.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0032418 lysosome localization(GO:0032418)
0.0 0.8 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 1.0 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 7.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 2.5 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.7 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.5 GO:0046683 response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.0 2.0 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.0 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 2.6 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 1.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.1 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 1.1 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 4.6 GO:0072657 protein localization to membrane(GO:0072657)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 2.0 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 1.3 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 2.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.0 GO:0018393 internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.2 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.2 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0046051 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0060030 dorsal convergence(GO:0060030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0034709 methylosome(GO:0034709)
2.4 19.5 GO:0042613 MHC class II protein complex(GO:0042613)
2.0 28.5 GO:0000815 ESCRT III complex(GO:0000815)
1.8 9.1 GO:0071439 clathrin complex(GO:0071439)
1.6 9.9 GO:0031258 lamellipodium membrane(GO:0031258)
1.6 4.9 GO:0031251 PAN complex(GO:0031251)
1.6 4.9 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
1.6 12.8 GO:0070765 gamma-secretase complex(GO:0070765)
1.5 6.1 GO:0019815 B cell receptor complex(GO:0019815)
1.5 9.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.5 6.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
1.5 31.5 GO:0005686 U2 snRNP(GO:0005686)
1.5 7.4 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
1.4 13.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.3 23.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.3 7.9 GO:0019008 molybdopterin synthase complex(GO:0019008)
1.2 10.8 GO:0000974 Prp19 complex(GO:0000974)
1.2 13.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.2 4.8 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.2 4.6 GO:0005688 U6 snRNP(GO:0005688)
1.2 8.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.0 6.0 GO:0030891 VCB complex(GO:0030891)
1.0 4.0 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.9 2.8 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.9 2.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.9 4.6 GO:0033263 CORVET complex(GO:0033263)
0.9 10.1 GO:0045095 keratin filament(GO:0045095)
0.9 5.5 GO:0070695 FHF complex(GO:0070695)
0.9 4.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.9 14.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.9 12.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.8 4.9 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.8 7.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.8 14.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.8 4.5 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.7 3.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.7 5.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.7 4.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.7 12.5 GO:0030057 desmosome(GO:0030057)
0.7 7.5 GO:0035101 FACT complex(GO:0035101)
0.7 14.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.7 12.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6 3.9 GO:0071986 Ragulator complex(GO:0071986)
0.6 4.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 3.6 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.6 3.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.6 2.3 GO:0097255 R2TP complex(GO:0097255)
0.6 4.0 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.6 2.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.6 2.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.6 5.0 GO:0031526 brush border membrane(GO:0031526)
0.5 4.9 GO:0005771 multivesicular body(GO:0005771)
0.5 3.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 4.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 7.4 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.5 22.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.5 7.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 29.9 GO:0031901 early endosome membrane(GO:0031901)
0.5 5.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 16.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.5 65.2 GO:0010008 endosome membrane(GO:0010008)
0.5 5.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.5 34.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.5 17.1 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.4 9.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 1.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 1.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 7.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 3.4 GO:0031984 organelle subcompartment(GO:0031984)
0.4 47.1 GO:0016607 nuclear speck(GO:0016607)
0.4 3.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 7.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.4 5.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.4 7.6 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.4 1.2 GO:0034457 Mpp10 complex(GO:0034457)
0.4 1.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.4 0.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.4 2.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 5.8 GO:0070187 telosome(GO:0070187)
0.4 3.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 52.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.4 4.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.4 2.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 2.8 GO:0000812 Swr1 complex(GO:0000812)
0.4 3.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 26.5 GO:0001726 ruffle(GO:0001726)
0.3 1.7 GO:0031501 mannosyltransferase complex(GO:0031501)
0.3 4.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 2.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 4.1 GO:0005876 spindle microtubule(GO:0005876)
0.3 1.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 3.4 GO:0005903 brush border(GO:0005903)
0.3 1.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 7.8 GO:0071141 SMAD protein complex(GO:0071141)
0.3 5.4 GO:0005801 cis-Golgi network(GO:0005801)
0.3 2.2 GO:0035517 PR-DUB complex(GO:0035517)
0.3 4.3 GO:0030008 TRAPP complex(GO:0030008)
0.3 0.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 8.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 1.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 8.5 GO:0005795 Golgi stack(GO:0005795)
0.3 1.1 GO:0043291 RAVE complex(GO:0043291)
0.3 94.6 GO:0000139 Golgi membrane(GO:0000139)
0.3 1.4 GO:0070390 transcription export complex 2(GO:0070390)
0.3 12.1 GO:0008305 integrin complex(GO:0008305)
0.3 5.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 3.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 2.4 GO:0016272 prefoldin complex(GO:0016272)
0.3 3.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 7.4 GO:0032040 small-subunit processome(GO:0032040)
0.3 11.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 0.8 GO:0044327 dendritic spine head(GO:0044327)
0.3 4.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 7.9 GO:0005902 microvillus(GO:0005902)
0.3 13.7 GO:0016592 mediator complex(GO:0016592)
0.2 1.9 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 1.4 GO:0070876 SOSS complex(GO:0070876)
0.2 1.7 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 0.9 GO:0005787 signal peptidase complex(GO:0005787)
0.2 4.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 4.8 GO:0030667 secretory granule membrane(GO:0030667)
0.2 3.4 GO:0036038 MKS complex(GO:0036038)
0.2 1.7 GO:0016586 RSC complex(GO:0016586)
0.2 3.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 17.2 GO:0005925 focal adhesion(GO:0005925)
0.2 3.1 GO:0005869 dynactin complex(GO:0005869)
0.2 1.5 GO:0015030 Cajal body(GO:0015030)
0.2 0.7 GO:0016460 myosin II complex(GO:0016460)
0.2 1.1 GO:0030870 Mre11 complex(GO:0030870)
0.2 16.9 GO:0005681 spliceosomal complex(GO:0005681)
0.2 13.1 GO:0098791 Golgi subcompartment(GO:0098791)
0.2 6.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 1.0 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 3.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 3.7 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.2 7.3 GO:0005811 lipid particle(GO:0005811)
0.2 3.6 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 3.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.3 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.3 GO:0044440 endosomal part(GO:0044440)
0.1 1.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 13.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 34.7 GO:0005794 Golgi apparatus(GO:0005794)
0.1 10.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 5.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.9 GO:0000145 exocyst(GO:0000145)
0.1 6.0 GO:0030141 secretory granule(GO:0030141)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 2.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.7 GO:0034708 methyltransferase complex(GO:0034708)
0.1 4.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 34.4 GO:0009986 cell surface(GO:0009986)
0.1 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 7.1 GO:0005774 vacuolar membrane(GO:0005774)
0.1 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818)
0.1 4.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.1 13.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.7 GO:0097346 INO80-type complex(GO:0097346)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 6.2 GO:0005764 lysosome(GO:0005764)
0.0 2.5 GO:0030027 lamellipodium(GO:0030027)
0.0 1.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.0 GO:0005769 early endosome(GO:0005769)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 9.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.6 GO:0005770 late endosome(GO:0005770)
0.0 2.4 GO:0005604 basement membrane(GO:0005604)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 13.5 GO:0005654 nucleoplasm(GO:0005654)
0.0 2.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 22.1 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
3.2 12.6 GO:0003796 lysozyme activity(GO:0003796)
3.2 9.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
3.0 8.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
2.8 30.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
2.8 19.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
2.6 7.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
2.3 9.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
2.2 6.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
2.0 7.9 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
2.0 7.9 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.9 5.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.8 5.3 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
1.7 12.1 GO:0019809 spermidine binding(GO:0019809)
1.6 4.9 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
1.6 12.8 GO:0003993 acid phosphatase activity(GO:0003993)
1.6 4.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.6 6.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.5 7.7 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
1.5 7.4 GO:0016531 copper chaperone activity(GO:0016531)
1.5 5.9 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.5 5.9 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.5 17.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 8.4 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
1.3 4.0 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
1.3 3.9 GO:0051765 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
1.2 3.7 GO:0045545 syndecan binding(GO:0045545)
1.2 4.9 GO:0051380 norepinephrine binding(GO:0051380)
1.2 3.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.2 3.6 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.2 8.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.2 20.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.1 4.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.1 4.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.1 7.9 GO:0035173 histone kinase activity(GO:0035173)
1.1 5.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
1.0 6.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.0 7.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.0 3.0 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
1.0 7.9 GO:0015057 thrombin receptor activity(GO:0015057)
1.0 19.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.0 8.6 GO:0016783 sulfurtransferase activity(GO:0016783)
1.0 2.9 GO:0031704 apelin receptor binding(GO:0031704)
1.0 3.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.9 2.8 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.9 9.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 7.2 GO:0015232 heme transporter activity(GO:0015232)
0.9 8.8 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.9 6.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.9 14.7 GO:0045159 myosin II binding(GO:0045159)
0.9 4.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.9 8.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.9 2.6 GO:0030623 U5 snRNA binding(GO:0030623)
0.8 8.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.8 4.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.8 3.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.8 6.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.8 17.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.8 4.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 2.4 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.8 7.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.8 6.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.8 8.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.8 11.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 2.9 GO:0008169 C-methyltransferase activity(GO:0008169)
0.7 10.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.7 14.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.7 4.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.7 7.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.7 2.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 2.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.7 9.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.7 2.6 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.6 9.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 0.6 GO:0031386 protein tag(GO:0031386)
0.6 1.9 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.6 1.9 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.6 10.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 1.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.6 10.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.6 4.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.6 1.8 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.6 3.0 GO:0004001 adenosine kinase activity(GO:0004001)
0.6 2.9 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.6 2.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.6 3.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.6 4.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.6 4.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.6 3.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.6 5.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 6.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.5 4.8 GO:0051920 peroxiredoxin activity(GO:0051920)
0.5 4.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.5 41.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.5 2.0 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.5 23.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 3.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.5 1.5 GO:0043621 protein self-association(GO:0043621)
0.5 6.4 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.5 2.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 17.7 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.5 7.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.5 19.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 1.9 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.5 3.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 4.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 1.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 3.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 1.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.5 5.9 GO:0008301 DNA binding, bending(GO:0008301)
0.4 1.8 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.4 4.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 3.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 2.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 1.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.4 4.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.4 7.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.4 11.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 4.7 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.4 3.2 GO:0019206 uridine kinase activity(GO:0004849) nucleoside kinase activity(GO:0019206)
0.4 2.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 1.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.4 3.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.4 1.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 1.9 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.4 0.8 GO:0070883 pre-miRNA binding(GO:0070883)
0.4 3.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.4 1.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 5.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.4 12.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.4 3.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.4 2.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 3.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.4 2.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 3.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.4 8.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 18.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.4 4.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 9.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 5.6 GO:0002039 p53 binding(GO:0002039)
0.3 1.0 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.3 5.5 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.3 9.9 GO:0051018 protein kinase A binding(GO:0051018)
0.3 1.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 2.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 2.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.3 1.7 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 3.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 6.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 7.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.3 7.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 1.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.3 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 4.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 9.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 4.1 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.3 1.5 GO:0032183 SUMO binding(GO:0032183)
0.3 7.2 GO:0031267 small GTPase binding(GO:0031267)
0.3 4.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 12.9 GO:0008013 beta-catenin binding(GO:0008013)
0.3 1.5 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.3 4.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 7.9 GO:0015248 sterol transporter activity(GO:0015248)
0.3 9.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 6.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 19.3 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.3 2.0 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3 10.1 GO:0004707 MAP kinase activity(GO:0004707)
0.3 10.3 GO:0019003 GDP binding(GO:0019003)
0.3 1.4 GO:0008430 selenium binding(GO:0008430)
0.3 6.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 1.9 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.3 5.3 GO:0097602 cullin family protein binding(GO:0097602)
0.3 2.7 GO:0030332 cyclin binding(GO:0030332)
0.3 1.1 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 3.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 3.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 2.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 1.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 2.2 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.2 5.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 3.4 GO:0015026 coreceptor activity(GO:0015026)
0.2 28.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.9 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 3.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 2.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 4.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 4.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 2.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 2.7 GO:0005158 insulin receptor binding(GO:0005158)
0.2 3.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 7.6 GO:0035064 methylated histone binding(GO:0035064)
0.2 2.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 2.0 GO:0050700 CARD domain binding(GO:0050700)
0.2 19.5 GO:0019905 syntaxin binding(GO:0019905)
0.2 1.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.9 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 18.2 GO:0000149 SNARE binding(GO:0000149)
0.2 11.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 3.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.9 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 2.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.2 1.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 2.2 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 3.8 GO:0070411 I-SMAD binding(GO:0070411)
0.2 5.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 43.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.7 GO:0004359 glutaminase activity(GO:0004359)
0.2 2.0 GO:0002020 protease binding(GO:0002020)
0.2 3.0 GO:0030145 manganese ion binding(GO:0030145)
0.2 0.5 GO:0035197 siRNA binding(GO:0035197)
0.2 0.5 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.2 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 5.3 GO:0030165 PDZ domain binding(GO:0030165)
0.2 2.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 5.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 61.4 GO:0005096 GTPase activator activity(GO:0005096)
0.2 2.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 6.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 6.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.6 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 1.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 2.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 3.8 GO:0000339 RNA cap binding(GO:0000339)
0.2 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 5.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 3.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 7.2 GO:0031491 nucleosome binding(GO:0031491)
0.1 17.3 GO:0060090 binding, bridging(GO:0060090)
0.1 3.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 6.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 6.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 3.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 9.7 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 11.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 10.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.4 GO:0001016 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 6.3 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1 3.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 60.5 GO:0008289 lipid binding(GO:0008289)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 7.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 7.5 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 5.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 10.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 4.4 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 5.2 GO:0019955 cytokine binding(GO:0019955)
0.1 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 3.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 19.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.1 GO:0016209 antioxidant activity(GO:0016209)
0.1 24.0 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1 3.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 3.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 17.8 GO:0003924 GTPase activity(GO:0003924)
0.1 1.0 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 9.6 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 3.4 GO:0045296 cadherin binding(GO:0045296)
0.0 1.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 2.3 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 6.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 26.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.5 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 1.5 GO:0004620 phospholipase activity(GO:0004620)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.6 GO:0046332 SMAD binding(GO:0046332)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 8.9 GO:0003723 RNA binding(GO:0003723)
0.0 0.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.6 GO:0016790 thiolester hydrolase activity(GO:0016790)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 15.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.0 13.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.9 5.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.9 13.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.9 45.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.7 28.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.7 4.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 19.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.6 15.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.6 12.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.6 9.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.6 7.7 PID ALK2 PATHWAY ALK2 signaling events
0.5 16.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.5 4.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5 6.3 PID ARF6 PATHWAY Arf6 signaling events
0.5 3.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 7.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.5 1.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.5 4.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.4 12.2 PID CD40 PATHWAY CD40/CD40L signaling
0.4 11.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 7.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3 18.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 2.5 PID BCR 5PATHWAY BCR signaling pathway
0.3 4.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 3.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.3 3.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 2.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.3 5.3 PID ARF 3PATHWAY Arf1 pathway
0.3 9.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 2.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 11.1 PID NOTCH PATHWAY Notch signaling pathway
0.3 10.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 10.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 2.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 2.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 6.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 5.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 3.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 2.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 2.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 4.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID P73PATHWAY p73 transcription factor network
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.3 14.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
1.3 7.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
1.2 19.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
1.2 9.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.1 18.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.1 2.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.1 12.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.0 14.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.0 11.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.0 8.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.9 11.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.8 5.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.8 13.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.8 10.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.8 3.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.8 21.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.7 6.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7 23.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.7 6.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.7 1.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.7 3.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.7 4.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.6 4.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.6 4.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.6 8.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6 7.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.6 6.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.5 11.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.5 9.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 8.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.5 11.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.5 11.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.5 10.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 3.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 1.9 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.5 18.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.5 4.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.5 4.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 5.0 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.4 3.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 1.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 4.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 6.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.4 4.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 6.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.4 11.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.4 1.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 3.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 5.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 4.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.3 4.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 6.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 7.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 3.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 2.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.3 17.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 23.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 7.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.3 3.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 5.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 29.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 5.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 3.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 5.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 7.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 12.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.2 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 3.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.7 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 6.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 2.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 1.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.2 5.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.2 5.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 3.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 7.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 5.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 4.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 8.6 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 3.1 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 4.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling