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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for emx2+emx3

Z-value: 1.11

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Transcription factors associated with emx2+emx3

Gene Symbol Gene ID Gene Info
emx3
ENSDARG00000020417 empty spiracles homeobox 3
emx2
ENSDARG00000039701 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
emx2dr11_v1_chr13_+_19322686_19322686-0.671.1e-13Click!
emx3dr11_v1_chr14_-_26377044_26377044-0.663.6e-13Click!

Activity profile of emx2+emx3 motif

Sorted Z-values of emx2+emx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31277415 13.24 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr11_+_11200550 12.45 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr25_+_31276842 11.71 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr12_-_17712393 11.64 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr1_-_18811517 9.23 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr19_-_10330778 9.13 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
ccdc106b
coiled-coil domain containing 106b
chr22_-_31060579 9.10 ENSDART00000182376
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr11_-_6452444 8.92 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr5_-_71705191 8.82 ENSDART00000187767
ak1
adenylate kinase 1
chr20_+_54309148 8.53 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr25_+_22320738 8.36 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr19_+_46158078 8.22 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr10_-_44560165 8.16 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr20_+_54299419 8.10 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr7_+_59020972 7.77 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr19_-_25149598 7.65 ENSDART00000162917
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr5_+_35458190 7.04 ENSDART00000051313
fbp1b
fructose-1,6-bisphosphatase 1b
chr20_+_54304800 6.72 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr8_-_23780334 6.65 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr2_+_41926707 6.39 ENSDART00000023208
zgc:110183
zgc:110183
chr23_+_32101202 6.28 ENSDART00000000992
zgc:56699
zgc:56699
chr24_+_39105051 6.27 ENSDART00000115297
mss51
MSS51 mitochondrial translational activator
chr4_+_25654686 6.25 ENSDART00000100714
acot16
acyl-CoA thioesterase 16
chr19_-_25149034 6.06 ENSDART00000148432
ENSDART00000175266
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr13_-_31622195 5.87 ENSDART00000057432
six1a
SIX homeobox 1a
chr23_+_26026383 5.46 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_-_10599062 5.41 ENSDART00000048003
tspan12
tetraspanin 12
chr4_+_9467049 5.34 ENSDART00000012659
zgc:55888
zgc:55888
chr6_-_46742455 5.33 ENSDART00000011970
zgc:66479
zgc:66479
chr21_+_18997511 5.29 ENSDART00000145591
rpl17
ribosomal protein L17
chr17_-_4245902 5.15 ENSDART00000151851
gdf3
growth differentiation factor 3
chr23_-_35064785 5.15 ENSDART00000172240
BX294434.1

chr16_+_1100559 5.09 ENSDART00000092657
adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr16_-_38118003 4.92 ENSDART00000058667
si:dkey-23o4.6
si:dkey-23o4.6
chr10_+_563252 4.89 ENSDART00000192123
bmp10l
bone morphogenetic protein 10, like
chr5_+_2815021 4.65 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr9_-_7390388 4.59 ENSDART00000132392
slc23a3
solute carrier family 23, member 3
chr20_-_43663494 4.54 ENSDART00000144564
BX470188.1

chr8_-_2616326 4.53 ENSDART00000027214
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr11_-_45171139 4.50 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
syngr2b
synaptogyrin 2b
chr15_+_34934568 4.50 ENSDART00000165210
zgc:66024
zgc:66024
chr23_-_19686791 4.49 ENSDART00000161973
zgc:193598
zgc:193598
chr2_+_19522082 4.42 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr19_-_20403845 4.40 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr20_-_40755614 4.35 ENSDART00000061247
cx32.3
connexin 32.3
chr19_-_20403507 4.27 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr22_+_17261801 4.10 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr12_+_30653047 4.07 ENSDART00000148562
thbs2b
thrombospondin 2b
chr9_-_5318873 3.91 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr3_-_59297532 3.89 ENSDART00000187991
CABZ01053748.1

chr15_-_14625373 3.85 ENSDART00000171841
slc5a2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr18_-_40708537 3.68 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr9_+_29548195 3.68 ENSDART00000176057
rnf17
ring finger protein 17
chr21_+_5882300 3.54 ENSDART00000165065
uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_-_19446529 3.51 ENSDART00000192353
sb:cb649
sb:cb649
chr7_+_19016023 3.45 ENSDART00000185212
CU972454.5

chr19_-_20403318 3.45 ENSDART00000136826
dazl
deleted in azoospermia-like
chr2_+_19578446 3.42 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr17_+_6469419 3.41 ENSDART00000191729
COQ8A (1 of many)
si:dkey-36g24.3
chr7_+_4474880 3.38 ENSDART00000143528
si:dkey-83f18.14
si:dkey-83f18.14
chr4_+_22480169 3.32 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr8_-_53044300 3.28 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr23_+_32039386 3.28 ENSDART00000133801
mylk2
myosin light chain kinase 2
chr14_+_46313396 3.26 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr16_+_32736588 3.26 ENSDART00000075191
ENSDART00000168358
zgc:172323
zgc:172323
chr6_+_49926115 3.20 ENSDART00000018523
ahcy
adenosylhomocysteinase
chr1_-_29139141 3.18 ENSDART00000075546
ENSDART00000133246
hsf2bp
heat shock transcription factor 2 binding protein
chr17_+_5985933 3.18 ENSDART00000190844
zgc:194275
zgc:194275
chr12_+_20587179 3.15 ENSDART00000170127
arsg
arylsulfatase G
chr18_+_5490668 3.14 ENSDART00000167035
mibp2
muscle-specific beta 1 integrin binding protein 2
chr7_+_4694762 3.14 ENSDART00000132862
si:ch211-225k7.3
si:ch211-225k7.3
chr3_+_23029484 3.06 ENSDART00000187900
nags
N-acetylglutamate synthase
chr25_-_28674739 3.06 ENSDART00000067073
lrrc10
leucine rich repeat containing 10
chr9_+_24065855 3.06 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr5_+_33498253 3.05 ENSDART00000140993
ms4a17c.2
membrane-spanning 4-domains, subfamily A, member 17c.2
chr17_+_8799661 3.01 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr5_+_6954162 2.96 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr3_-_12026741 2.94 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr2_-_19520324 2.93 ENSDART00000079877
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr19_+_43780970 2.93 ENSDART00000063870
rpl11
ribosomal protein L11
chr2_+_19633493 2.92 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr13_+_7442023 2.87 ENSDART00000080975
tnfaip2b
tumor necrosis factor, alpha-induced protein 2b
chr10_+_24468922 2.82 ENSDART00000008248
ENSDART00000183510
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr25_+_14092871 2.81 ENSDART00000067239
guca1g
guanylate cyclase activator 1g
chr17_+_12285285 2.80 ENSDART00000154336
pimr174
Pim proto-oncogene, serine/threonine kinase, related 174
chr2_+_14992879 2.78 ENSDART00000137546
pimr55
Pim proto-oncogene, serine/threonine kinase, related 55
chr1_-_55785722 2.75 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr3_+_40164129 2.73 ENSDART00000102526
gfer
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr2_-_19520690 2.72 ENSDART00000133559
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr18_-_977075 2.72 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr6_+_612594 2.72 ENSDART00000150903
kynu
kynureninase
chr25_-_13188678 2.72 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr4_+_7817996 2.71 ENSDART00000166809
si:ch1073-67j19.1
si:ch1073-67j19.1
chr10_+_35257651 2.69 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr4_-_948776 2.68 ENSDART00000023483
sim1b
single-minded family bHLH transcription factor 1b
chr10_-_34916208 2.67 ENSDART00000187371
ccna1
cyclin A1
chr7_+_4694924 2.67 ENSDART00000144873
si:ch211-225k7.3
si:ch211-225k7.3
chr5_+_44944778 2.63 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
dmrt1
doublesex and mab-3 related transcription factor 1
chr18_-_6766354 2.60 ENSDART00000132611
adm2b
adrenomedullin 2b
chr2_+_19578079 2.58 ENSDART00000144413
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr11_-_10456387 2.57 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr6_-_2627488 2.51 ENSDART00000044089
ENSDART00000158333
ENSDART00000155109
hyi
hydroxypyruvate isomerase
chr10_+_26990095 2.51 ENSDART00000064111
faub
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr15_+_11427620 2.50 ENSDART00000168688
ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr14_+_29941445 2.50 ENSDART00000181761
fam149a
family with sequence similarity 149 member A
chr2_-_19576640 2.47 ENSDART00000141021
pimr51
Pim proto-oncogene, serine/threonine kinase, related 51
chr9_+_28598577 2.45 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
si:ch73-7i4.1
chr12_-_29305533 2.45 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr24_-_25184553 2.43 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr13_+_35528607 2.36 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr23_+_4709607 2.33 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr14_+_29941266 2.32 ENSDART00000112757
fam149a
family with sequence similarity 149 member A
chr18_-_25279323 2.32 ENSDART00000191547
plin1
perilipin 1
chr20_+_46202188 2.31 ENSDART00000100523
taar13c
trace amine associated receptor 13c
chr20_+_37393134 2.30 ENSDART00000128321
adgrg6
adhesion G protein-coupled receptor G6
chr25_-_27621268 2.30 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr10_-_35257458 2.30 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr18_+_45483282 2.29 ENSDART00000183725
cngb1a
cyclic nucleotide gated channel beta 1a
chr2_+_15100742 2.27 ENSDART00000027171
f3b
coagulation factor IIIb
chr11_+_30091155 2.27 ENSDART00000158691
si:ch211-161f7.2
si:ch211-161f7.2
chr21_+_6394929 2.24 ENSDART00000138600
si:ch211-225g23.1
si:ch211-225g23.1
chr21_-_37933833 2.22 ENSDART00000184138
ENSDART00000177664
FO704750.1

chr9_-_22355391 2.22 ENSDART00000009115
crygm3
crystallin, gamma M3
chr15_-_39955785 2.21 ENSDART00000154556
msh5
mutS homolog 5
chr3_+_23029934 2.21 ENSDART00000110343
nags
N-acetylglutamate synthase
chr2_+_45548890 2.19 ENSDART00000113994
fndc7a
fibronectin type III domain containing 7a
chr4_-_72513569 2.19 ENSDART00000174130
CR788316.4

chr12_-_314899 2.19 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr23_-_306796 2.19 ENSDART00000143125
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr18_+_33264609 2.19 ENSDART00000050639
v2ra20
vomeronasal 2 receptor, a20
chr1_-_513762 2.17 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr20_+_46183505 2.17 ENSDART00000060799
taar13b
trace amine associated receptor 13b
chr24_+_42004640 2.17 ENSDART00000171380
top1mt
DNA topoisomerase I mitochondrial
chr19_+_31873308 2.13 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
si:dkeyp-34f6.4
chr13_-_15082024 2.10 ENSDART00000157482
sfxn5a
sideroflexin 5a
chr23_-_16484383 2.10 ENSDART00000187839
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr7_-_38638809 2.09 ENSDART00000144341
c6ast4
six-cysteine containing astacin protease 4
chr16_-_50897887 2.08 ENSDART00000156985
si:ch73-90p23.1
si:ch73-90p23.1
chr12_+_31775182 2.06 ENSDART00000192235
lrrc59
leucine rich repeat containing 59
chr17_+_23584268 2.05 ENSDART00000192675
slc16a12a
solute carrier family 16, member 12a
chr1_-_9629705 2.05 ENSDART00000166601
ENSDART00000164079
ugt5b5
UDP glucuronosyltransferase 5 family, polypeptide B5
chr13_-_52089003 2.04 ENSDART00000187600
tmem254
transmembrane protein 254
chr7_-_38638276 2.04 ENSDART00000074463
c6ast4
six-cysteine containing astacin protease 4
chr11_-_10456553 2.02 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr9_+_48761455 2.00 ENSDART00000139631
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr12_+_45238292 1.96 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr23_+_41679586 1.96 ENSDART00000067662
CU914487.1

chr12_+_9250107 1.95 ENSDART00000152249
pimr46
Pim proto-oncogene, serine/threonine kinase, related 46
chr16_+_30483043 1.95 ENSDART00000188034
pear1
platelet endothelial aggregation receptor 1
chr8_-_24803111 1.95 ENSDART00000186281
BX324132.3

chr23_-_19140781 1.93 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr24_+_39468178 1.92 ENSDART00000183613
dnah3
dynein axonemal heavy chain 3
chr10_-_17550239 1.91 ENSDART00000057513
ska1
spindle and kinetochore associated complex subunit 1
chr1_+_40158146 1.91 ENSDART00000145694
si:ch211-113e8.9
si:ch211-113e8.9
chr23_-_44965582 1.91 ENSDART00000163367
tfr2
transferrin receptor 2
chr18_+_33521609 1.90 ENSDART00000147592
v2rh7
vomeronasal 2 receptor, h7
chr22_+_31207226 1.90 ENSDART00000180016
grip2b
glutamate receptor interacting protein 2b
chr19_-_2822372 1.89 ENSDART00000109130
ENSDART00000122385
recql4
RecQ helicase-like 4
chr20_+_11731039 1.88 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr3_-_23643751 1.87 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr8_-_47770365 1.86 ENSDART00000146775
kank3
KN motif and ankyrin repeat domains 3
chr9_-_22147567 1.85 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr17_-_11357851 1.85 ENSDART00000153915
si:ch211-185a18.2
si:ch211-185a18.2
chr5_+_72194444 1.82 ENSDART00000165436
ddx54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr2_+_20406399 1.82 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr15_+_17728180 1.82 ENSDART00000081105
si:ch211-213d14.1
si:ch211-213d14.1
chr3_+_52545014 1.82 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr10_+_31222433 1.81 ENSDART00000185080
tmem218
transmembrane protein 218
chr21_-_38618540 1.79 ENSDART00000036600
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_-_17235891 1.79 ENSDART00000144251
artnb
artemin b
chr5_+_37903790 1.79 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr15_+_5299404 1.78 ENSDART00000155410
or122-2
odorant receptor, family E, subfamily 122, member 2
chr7_+_15659280 1.78 ENSDART00000173414
mef2ab
myocyte enhancer factor 2ab
chr6_+_39905021 1.78 ENSDART00000064904
endou
endonuclease, polyU-specific
chr25_+_13157165 1.77 ENSDART00000155653
si:dkeyp-50b9.1
si:dkeyp-50b9.1
chr15_-_5740358 1.76 ENSDART00000183563
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr21_-_45363871 1.76 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
PPP2CA
zgc:56064
chr3_-_34052882 1.75 ENSDART00000151463
ighv11-1
immunoglobulin heavy variable 11-1
chr20_+_37457642 1.75 ENSDART00000132771
adgrg6
adhesion G protein-coupled receptor G6
chr5_+_60934345 1.74 ENSDART00000179772
rph3al
rabphilin 3A-like (without C2 domains)
chr22_+_19366866 1.73 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr6_+_14980761 1.72 ENSDART00000087782
mrps9
mitochondrial ribosomal protein S9
chr2_+_37227011 1.72 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr23_+_19691146 1.72 ENSDART00000143001
si:dkey-93l1.6
si:dkey-93l1.6
chr22_+_31207799 1.72 ENSDART00000133267
grip2b
glutamate receptor interacting protein 2b
chr8_+_53080515 1.71 ENSDART00000143009
wdr46
WD repeat domain 46
chr5_+_27434601 1.71 ENSDART00000064701
loxl2b
lysyl oxidase-like 2b
chr15_-_40157513 1.71 ENSDART00000184014
si:ch211-281l24.3
si:ch211-281l24.3
chr6_+_7533601 1.70 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr8_-_22273819 1.69 ENSDART00000121513
nphp4
nephronophthisis 4
chr5_-_48268049 1.69 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr23_-_14766902 1.68 ENSDART00000168113
gss
glutathione synthetase
chr9_-_22099536 1.68 ENSDART00000101923
CR391987.1

chr2_+_30182431 1.67 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr12_-_48188928 1.66 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr6_+_60004871 1.66 ENSDART00000179832
CABZ01079267.1

chr19_+_25154066 1.66 ENSDART00000163220
si:ch211-239d6.2
si:ch211-239d6.2
chr8_+_20679759 1.66 ENSDART00000088668
nfic
nuclear factor I/C
chr15_+_5343186 1.66 ENSDART00000170086
CABZ01018874.1

chr6_-_52788213 1.64 ENSDART00000179880
rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like

Network of associatons between targets according to the STRING database.

First level regulatory network of emx2+emx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0010265 SCF complex assembly(GO:0010265)
2.3 7.0 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
2.0 12.1 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.7 8.4 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
1.5 6.0 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
1.4 4.1 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
1.3 5.4 GO:0006526 arginine biosynthetic process(GO:0006526)
1.3 8.8 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.9 2.7 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.9 2.6 GO:0030238 male sex determination(GO:0030238)
0.8 4.0 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.8 4.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.7 2.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.7 2.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.5 8.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.5 1.6 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.5 3.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 2.0 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.5 1.9 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.4 2.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.4 22.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 1.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.4 1.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.4 1.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.4 4.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.4 1.6 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.4 1.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.4 4.6 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.4 1.8 GO:1903726 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.4 2.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.4 1.8 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.4 1.8 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.4 3.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 5.5 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 1.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 2.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 1.3 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.3 7.8 GO:0030497 fatty acid elongation(GO:0030497)
0.3 0.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.3 1.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.3 3.3 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.3 1.2 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3 2.9 GO:0051601 exocyst localization(GO:0051601)
0.3 1.1 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.3 7.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.3 1.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.3 3.6 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.3 3.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 1.0 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 2.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.9 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2 0.9 GO:1903232 melanosome assembly(GO:1903232)
0.2 2.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 3.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.2 2.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 1.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 8.2 GO:0071711 basement membrane organization(GO:0071711)
0.2 2.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 3.0 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.2 0.6 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 1.9 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 1.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 1.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.7 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.2 0.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 0.7 GO:0032475 otolith formation(GO:0032475)
0.2 1.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 1.4 GO:0051013 microtubule severing(GO:0051013)
0.2 2.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 1.0 GO:0035889 otolith tethering(GO:0035889)
0.2 3.0 GO:0031297 replication fork processing(GO:0031297)
0.1 2.9 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 1.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 2.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 2.2 GO:0006265 DNA topological change(GO:0006265)
0.1 1.0 GO:2001286 optomotor response(GO:0071632) caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.4 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 1.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 1.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.9 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 4.9 GO:0060840 artery development(GO:0060840)
0.1 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.8 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 1.4 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.7 GO:0031179 peptide modification(GO:0031179)
0.1 0.4 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.1 4.1 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.1 30.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 2.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 8.5 GO:0007283 spermatogenesis(GO:0007283)
0.1 2.8 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.7 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 6.3 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 13.5 GO:0007601 visual perception(GO:0007601)
0.1 0.8 GO:0032264 IMP salvage(GO:0032264)
0.1 0.8 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.8 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 0.2 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 1.5 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 2.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.4 GO:1990798 pancreas regeneration(GO:1990798)
0.1 1.3 GO:0015671 oxygen transport(GO:0015671)
0.1 5.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.3 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.1 0.8 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.5 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 7.2 GO:0006936 muscle contraction(GO:0006936)
0.1 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.2 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.9 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 2.1 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 1.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 1.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.2 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0002031 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 1.7 GO:0060914 heart formation(GO:0060914)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 1.0 GO:0001878 response to yeast(GO:0001878)
0.0 1.9 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 2.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444) mitochondrial calcium ion homeostasis(GO:0051560)
0.0 1.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.7 GO:0060119 inner ear receptor cell development(GO:0060119)
0.0 0.6 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.5 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.5 GO:0006364 rRNA processing(GO:0006364)
0.0 2.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0033391 chromatoid body(GO:0033391)
1.4 5.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.9 2.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.6 12.5 GO:0031430 M band(GO:0031430)
0.5 22.5 GO:0005861 troponin complex(GO:0005861)
0.4 3.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 3.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 0.9 GO:0034457 Mpp10 complex(GO:0034457)
0.3 0.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.9 GO:0036156 inner dynein arm(GO:0036156)
0.3 2.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 0.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.9 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 8.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.8 GO:0016460 myosin II complex(GO:0016460)
0.2 0.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.2 1.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.6 GO:0043291 RAVE complex(GO:0043291)
0.1 1.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 8.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.7 GO:0097546 ciliary base(GO:0097546)
0.1 1.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 4.0 GO:0005811 lipid particle(GO:0005811)
0.1 1.9 GO:0000145 exocyst(GO:0000145)
0.1 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 9.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 17.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 7.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.4 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 2.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 11.1 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.3 GO:0030286 dynein complex(GO:0030286)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 6.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 21.5 GO:0005576 extracellular region(GO:0005576)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.9 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 3.2 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
2.7 8.2 GO:0008179 adenylate cyclase binding(GO:0008179)
2.3 7.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.9 7.8 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.8 5.3 GO:0034618 arginine binding(GO:0034618)
1.5 4.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
1.3 12.1 GO:0008494 translation activator activity(GO:0008494)
1.1 3.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.9 2.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.7 8.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 3.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 2.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5 2.2 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.5 2.2 GO:0033149 FFAT motif binding(GO:0033149)
0.5 2.0 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.5 1.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.4 3.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 5.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 1.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 1.1 GO:0004061 arylformamidase activity(GO:0004061)
0.4 1.8 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.4 2.8 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 2.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.3 5.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 2.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 1.3 GO:0070052 collagen V binding(GO:0070052)
0.3 1.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.3 1.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.3 6.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.3 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 3.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.7 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 5.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 2.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 2.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 2.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 0.8 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.2 1.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.2 2.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 4.1 GO:0043236 laminin binding(GO:0043236)
0.2 0.8 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 0.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.0 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 3.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.0 GO:0019843 rRNA binding(GO:0019843)
0.1 2.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 7.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 1.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 8.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 3.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.7 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 3.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.0 GO:0070628 proteasome binding(GO:0070628)
0.1 0.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 10.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 12.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 11.9 GO:0042393 histone binding(GO:0042393)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 8.5 GO:0008083 growth factor activity(GO:0008083)
0.0 1.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.2 GO:0005112 Notch binding(GO:0005112)
0.0 1.2 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.6 GO:2001069 glycogen binding(GO:2001069)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 11.9 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 1.0 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 3.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 4.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 2.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 14.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 2.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 1.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 4.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 3.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 7.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 2.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 3.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 3.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 9.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 4.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 1.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 8.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 3.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 4.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 8.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.8 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism