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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for esrrd+esrrga_esrrb_esrra+esrrgb

Z-value: 1.58

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Transcription factors associated with esrrd+esrrga_esrrb_esrra+esrrgb

Gene Symbol Gene ID Gene Info
esrrga
ENSDARG00000004861 estrogen-related receptor gamma a
esrrd
ENSDARG00000015064 estrogen-related receptor delta
esrrb
ENSDARG00000100847 estrogen-related receptor beta
esrrgb
ENSDARG00000011696 estrogen-related receptor gamma b
esrra
ENSDARG00000069266 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
esrrgbdr11_v1_chr20_-_46817223_46817223-0.541.6e-08Click!
esrrddr11_v1_chr18_-_48992363_48992363-0.495.5e-07Click!
esrrbdr11_v1_chr17_-_29902187_29902187-0.321.7e-03Click!
esrradr11_v1_chr21_+_26606741_26606741-0.205.8e-02Click!

Activity profile of esrrd+esrrga_esrrb_esrra+esrrgb motif

Sorted Z-values of esrrd+esrrga_esrrb_esrra+esrrgb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39568290 29.93 ENSDART00000020741
aldoaa
aldolase a, fructose-bisphosphate, a
chr2_-_24289641 29.26 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr16_-_17197546 28.87 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr15_+_20403903 21.61 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr6_-_15653494 21.60 ENSDART00000038133
trim63a
tripartite motif containing 63a
chr23_+_44611864 18.11 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr13_+_50375800 16.62 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr6_-_10835849 15.57 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr19_-_32487469 15.07 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr21_+_5080789 14.35 ENSDART00000024199
atp5fa1
ATP synthase F1 subunit alpha
chr9_-_42861080 13.51 ENSDART00000193688
ttn.1
titin, tandem duplicate 1
chr2_+_30916188 12.95 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr11_-_25213651 12.90 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr4_+_2620751 12.65 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr6_-_1514767 12.28 ENSDART00000067586
chchd6b
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr14_+_1014109 12.13 ENSDART00000157945
f8
coagulation factor VIII, procoagulant component
chr5_-_37886063 11.43 ENSDART00000131378
ENSDART00000132152
si:ch211-139a5.9
si:ch211-139a5.9
chr2_+_55982940 11.00 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr6_-_39764995 10.64 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr6_-_39765546 10.29 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr18_-_226800 10.13 ENSDART00000165180
tarsl2
threonyl-tRNA synthetase-like 2
chr3_+_1182315 9.95 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr15_+_404891 9.83 ENSDART00000155682
nipsnap2
nipsnap homolog 2
chr12_-_47648538 9.75 ENSDART00000108477
fh
fumarate hydratase
chr14_-_33454595 9.25 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr9_-_42873700 9.14 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr23_+_18722715 8.70 ENSDART00000137438
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr24_-_23974559 8.61 ENSDART00000080510
ENSDART00000135242
ndufb4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4
chr3_-_60142530 8.56 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr2_+_55982300 8.55 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr3_+_24207243 8.53 ENSDART00000023454
ENSDART00000136400
adsl
adenylosuccinate lyase
chr23_+_18722915 8.36 ENSDART00000025057
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr12_-_26415499 8.29 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr25_+_25124684 8.16 ENSDART00000167542
ldha
lactate dehydrogenase A4
chr10_+_22775253 8.08 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr8_-_17997845 8.08 ENSDART00000121660
acot11b
acyl-CoA thioesterase 11b
chr9_-_1970071 7.99 ENSDART00000080608
hoxd10a
homeobox D10a
chr21_+_5882300 7.90 ENSDART00000165065
uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr6_+_40714811 7.61 ENSDART00000153868
ccdc36
coiled-coil domain containing 36
chr23_-_21515182 7.24 ENSDART00000142000
rnf207b
ring finger protein 207b
chr16_-_5721386 7.23 ENSDART00000136655
ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr21_+_15704556 7.06 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr1_+_580642 6.99 ENSDART00000147633
mrpl39
mitochondrial ribosomal protein L39
chr6_+_28124393 6.73 ENSDART00000089195
gpr17
G protein-coupled receptor 17
chr5_-_24044877 6.54 ENSDART00000161131
pdha1a
pyruvate dehydrogenase E1 alpha 1 subunit a
chr7_+_20475788 6.36 ENSDART00000171155
si:dkey-19b23.13
si:dkey-19b23.13
chr15_-_23645810 6.29 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr3_+_58167288 6.16 ENSDART00000155874
ENSDART00000010395
uqcrc2a
ubiquinol-cytochrome c reductase core protein 2a
chr14_+_30340251 6.14 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr16_-_50229193 6.13 ENSDART00000161782
ENSDART00000010081
etfb
electron-transfer-flavoprotein, beta polypeptide
chr22_+_25720725 6.08 ENSDART00000150778
si:dkeyp-98a7.8
si:dkeyp-98a7.8
chr19_+_712127 6.08 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr11_+_30513656 5.94 ENSDART00000008594
tmem178
transmembrane protein 178
chr5_-_24044724 5.87 ENSDART00000023784
pdha1a
pyruvate dehydrogenase E1 alpha 1 subunit a
chr12_-_25201576 5.80 ENSDART00000077188
cox7a3
cytochrome c oxidase subunit VIIa polypeptide 3
chr6_+_22337081 5.79 ENSDART00000128047
ENSDART00000138930
uqcrc1
ubiquinol-cytochrome c reductase core protein 1
chr10_-_42685512 5.72 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr18_+_30508729 5.68 ENSDART00000185140
cox4i1
cytochrome c oxidase subunit IV isoform 1
chr16_+_16826504 5.65 ENSDART00000108691
kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
chr6_+_52235441 5.58 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr11_+_21076872 5.57 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr9_+_22359919 5.31 ENSDART00000009591
crygs4
crystallin, gamma S4
chr15_+_11427620 5.16 ENSDART00000168688
ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr24_-_6024466 5.13 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr8_+_45338073 5.08 ENSDART00000185024
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr18_+_30507839 5.08 ENSDART00000026866
cox4i1
cytochrome c oxidase subunit IV isoform 1
chr14_-_29826659 5.00 ENSDART00000138413
sorbs2b
sorbin and SH3 domain containing 2b
chr22_+_19453822 4.86 ENSDART00000141371
si:dkey-78l4.6
si:dkey-78l4.6
chr19_+_30990815 4.81 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr3_-_13599482 4.72 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr14_-_35892767 4.70 ENSDART00000052648
tmem144b
transmembrane protein 144b
chr9_-_21067971 4.64 ENSDART00000004333
tbx15
T-box 15
chr11_+_29671661 4.63 ENSDART00000024318
ENSDART00000165024
rnf207a
ring finger protein 207a
chr11_-_11471857 4.63 ENSDART00000030103
krt94
keratin 94
chr1_+_51221320 4.60 ENSDART00000138878
ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr7_+_22293894 4.57 ENSDART00000056790
tmem256
transmembrane protein 256
chr10_+_8437930 4.52 ENSDART00000074553
pptc7b
PTC7 protein phosphatase homolog b
chr20_-_52967878 4.51 ENSDART00000164460
gata4
GATA binding protein 4
chr1_+_29862074 4.40 ENSDART00000133905
ENSDART00000136786
ENSDART00000135252
pcca
propionyl CoA carboxylase, alpha polypeptide
chr11_+_13207898 4.28 ENSDART00000060310
atp5f1b
ATP synthase F1 subunit beta
chr5_+_61738276 4.28 ENSDART00000186256
RASL10B
RAS like family 10 member B
chr23_+_36087219 4.26 ENSDART00000154825
hoxc3a
homeobox C3a
chr6_-_33878665 4.26 ENSDART00000129916
tmem69
transmembrane protein 69
chr16_-_46578523 4.15 ENSDART00000131061
si:dkey-152b24.6
si:dkey-152b24.6
chr17_-_26610814 4.14 ENSDART00000133402
ENSDART00000016608
mrpl57
mitochondrial ribosomal protein L57
chr11_+_11201096 4.12 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr1_-_21287724 4.05 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr3_+_2669813 4.04 ENSDART00000014205
CR388047.1

chr6_+_50381665 4.04 ENSDART00000141128
cyc1
cytochrome c-1
chr1_-_55262763 4.02 ENSDART00000152769
si:ch211-286b5.4
si:ch211-286b5.4
chr18_+_5273953 4.02 ENSDART00000165073
slc12a1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr6_+_29402997 4.02 ENSDART00000104298
ndufb5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5
chr1_-_52167509 3.99 ENSDART00000184935
BX901942.2

chr10_+_9410304 3.92 ENSDART00000080843
ndufa8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr1_-_58868306 3.91 ENSDART00000166615
dnm2b
dynamin 2b
chr1_-_35653560 3.91 ENSDART00000142154
frem3
Fras1 related extracellular matrix 3
chr18_-_24988645 3.89 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr10_+_22782522 3.88 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr13_-_12660318 3.83 ENSDART00000008498
adh8a
alcohol dehydrogenase 8a
chr21_-_22669669 3.71 ENSDART00000101784
gig2j
grass carp reovirus (GCRV)-induced gene 2j
chr18_+_5547185 3.69 ENSDART00000193977
nnt2
nicotinamide nucleotide transhydrogenase 2
chr14_-_36412473 3.66 ENSDART00000128244
ENSDART00000138376
asb5a
ankyrin repeat and SOCS box containing 5a
chr20_-_10487951 3.57 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr17_+_23554932 3.50 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr6_+_42693114 3.49 ENSDART00000154353
si:ch211-207d10.2
si:ch211-207d10.2
chr10_+_7671260 3.47 ENSDART00000157608
fam136a
family with sequence similarity 136, member A
chr24_+_2495197 3.44 ENSDART00000146887
f13a1a.1
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr21_-_22681534 3.44 ENSDART00000159233
gig2f
grass carp reovirus (GCRV)-induced gene 2f
chr12_-_33359052 3.42 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr20_+_218886 3.42 ENSDART00000002661
lama4
laminin, alpha 4
chr3_+_39566999 3.42 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr7_+_32605705 3.41 ENSDART00000173841
fshb
follicle stimulating hormone, beta polypeptide
chr22_+_24215007 3.36 ENSDART00000162227
glrx2
glutaredoxin 2
chr11_+_18175893 3.29 ENSDART00000177625
zgc:173545
zgc:173545
chr19_-_7291733 3.25 ENSDART00000015559
sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr9_-_1986014 3.24 ENSDART00000142842
hoxd12a
homeobox D12a
chr8_+_20825987 3.22 ENSDART00000133309
si:ch211-133l5.4
si:ch211-133l5.4
chr6_+_42693288 3.19 ENSDART00000155010
si:ch211-207d10.2
si:ch211-207d10.2
chr8_+_37111643 3.18 ENSDART00000061336
ren
renin
chr10_-_40514643 3.17 ENSDART00000140705
taar19k
trace amine associated receptor 19k
chr3_+_61185660 3.11 ENSDART00000167114
CR352263.1

chr6_-_10912424 3.06 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr25_+_36311333 3.05 ENSDART00000190174
hist1h2a2
histone cluster 1 H2A family member 2
chr10_-_36691681 3.03 ENSDART00000122375
mrpl48
mitochondrial ribosomal protein L48
chr11_+_705727 3.03 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr25_-_29316193 3.02 ENSDART00000088249
hcn4l
hyperpolarization activated cyclic nucleotide-gated potassium channel 4l
chr11_+_18037729 2.96 ENSDART00000111624
zgc:175135
zgc:175135
chr8_-_17926814 2.96 ENSDART00000147344
lhx8b
LIM homeobox 8b
chr24_+_25471196 2.96 ENSDART00000066625
smpx
small muscle protein, X-linked
chr8_-_17926620 2.94 ENSDART00000187864
lhx8b
LIM homeobox 8b
chr13_+_30572172 2.92 ENSDART00000010052
ENSDART00000144417
ppifa
peptidylprolyl isomerase Fa
chr23_+_24272421 2.91 ENSDART00000029974
clcnk
chloride channel K
chr5_+_39936896 2.90 ENSDART00000135126
si:ch73-138i16.1
si:ch73-138i16.1
chr7_-_58130703 2.90 ENSDART00000172082
ank2b
ankyrin 2b, neuronal
chr9_+_30464641 2.89 ENSDART00000128357
gja5a
gap junction protein, alpha 5a
chr3_+_20001608 2.87 ENSDART00000137944
asb16
ankyrin repeat and SOCS box containing 16
chr3_+_13624815 2.83 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr22_-_38258053 2.83 ENSDART00000132516
elavl2
ELAV like neuron-specific RNA binding protein 2
chr1_-_27743985 2.82 ENSDART00000165515
si:dkey-29d5.2
si:dkey-29d5.2
chr10_-_57270 2.78 ENSDART00000058411
hlcs
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr10_+_10677697 2.77 ENSDART00000188705
fam163b
family with sequence similarity 163, member B
chr13_-_42724645 2.77 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr23_+_16430559 2.77 ENSDART00000112436
ntsr1
neurotensin receptor 1 (high affinity)
chr2_-_127945 2.77 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr23_+_16469530 2.75 ENSDART00000132898
ntsr1
neurotensin receptor 1 (high affinity)
chr3_+_3454610 2.74 ENSDART00000024900
zgc:165453
zgc:165453
chr11_+_18053333 2.74 ENSDART00000075750
zgc:175135
zgc:175135
chr13_-_9311253 2.73 ENSDART00000058056
mrps26
mitochondrial ribosomal protein S26
chr11_-_22361306 2.72 ENSDART00000180688
ENSDART00000182200
ENSDART00000006580
tfeb
transcription factor EB
chr9_+_27371240 2.69 ENSDART00000060337
tlr20.3
toll-like receptor 20, tandem duplicate 3
chr23_-_35082494 2.69 ENSDART00000189809
BX294434.1

chr6_+_50381347 2.68 ENSDART00000055504
cyc1
cytochrome c-1
chr25_-_29080063 2.68 ENSDART00000181911
ENSDART00000138087
cox5aa
cytochrome c oxidase subunit Vaa
chr2_+_30249977 2.68 ENSDART00000109160
ENSDART00000135171
tmem70
transmembrane protein 70
chr1_+_9994811 2.64 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr18_-_39636348 2.64 ENSDART00000129828
cyp19a1a
cytochrome P450, family 19, subfamily A, polypeptide 1a
chr9_+_32930622 2.55 ENSDART00000100928
cnga4
cyclic nucleotide gated channel alpha 4
chr25_-_19648154 2.50 ENSDART00000148570
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr2_-_5199431 2.50 ENSDART00000063384
phb2a
prohibitin 2a
chr18_+_8340886 2.46 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr14_+_46020571 2.45 ENSDART00000157617
ENSDART00000083928
c1qtnf2
C1q and TNF related 2
chr17_-_36818176 2.45 ENSDART00000061762
myo6b
myosin VIb
chr25_+_16214854 2.45 ENSDART00000109672
ENSDART00000190093
mical2b
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr14_-_38878356 2.44 ENSDART00000173082
ENSDART00000039788
uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr24_-_21847945 2.44 ENSDART00000189097
CR352265.4

chr11_+_18130300 2.43 ENSDART00000169146
zgc:175135
zgc:175135
chr2_+_30032303 2.43 ENSDART00000151841
rbm33b
RNA binding motif protein 33b
chr6_+_27418541 2.42 ENSDART00000187410
crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr18_+_7456888 2.38 ENSDART00000081468
terb1
telomere repeat binding bouquet formation protein 1
chr22_-_7050 2.38 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr21_-_25416391 2.37 ENSDART00000114081
sms
spermine synthase
chr7_-_24046999 2.36 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr11_+_18157260 2.36 ENSDART00000144659
zgc:173545
zgc:173545
chr9_+_22003942 2.36 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr6_-_54180699 2.35 ENSDART00000045901
rps10
ribosomal protein S10
chr15_-_7598542 2.34 ENSDART00000173092
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr23_-_10017245 2.34 ENSDART00000131669
plxnb1a
plexin b1a
chr16_+_20871021 2.34 ENSDART00000006429
hibadhb
3-hydroxyisobutyrate dehydrogenase b
chr9_+_29548195 2.32 ENSDART00000176057
rnf17
ring finger protein 17
chr19_-_5103313 2.31 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr7_+_35068036 2.31 ENSDART00000022139
zgc:136461
zgc:136461
chr18_+_27926839 2.25 ENSDART00000191835
hipk3b
homeodomain interacting protein kinase 3b
chr11_-_12198765 2.23 ENSDART00000104203
ENSDART00000128364
ENSDART00000166887
ENSDART00000041533
krt95
kertain 95
chr7_+_9981757 2.19 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr13_-_2520843 2.18 ENSDART00000187313
ENSDART00000170333
cox20
COX20 cytochrome c oxidase assembly factor
chr8_+_37749263 2.18 ENSDART00000108556
ENSDART00000147942
npm2a
nucleophosmin/nucleoplasmin, 2a
chr1_-_55810730 2.18 ENSDART00000100551
zgc:136908
zgc:136908
chr3_-_34136368 2.17 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr18_+_910992 2.16 ENSDART00000161206
ENSDART00000167229
pkma
pyruvate kinase M1/2a
chr21_-_20381481 2.16 ENSDART00000115236
atp5mea
ATP synthase membrane subunit ea
chr16_+_25259313 2.15 ENSDART00000058938
fbxo32
F-box protein 32
chr2_+_53359234 2.15 ENSDART00000147581
celf5b
cugbp, Elav-like family member 5b
chr1_-_55248496 2.14 ENSDART00000098615
nanos3
nanos homolog 3
chr10_-_24937070 2.14 ENSDART00000064459
si:ch211-214k5.3
si:ch211-214k5.3
chr2_+_42191592 2.12 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr13_+_36633355 2.12 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr9_+_27379193 2.11 ENSDART00000142656
tlr20.4
toll-like receptor 20, tandem duplicate 4
chr11_+_5842632 2.11 ENSDART00000111374
ENSDART00000158599
ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
chr6_+_19383267 2.11 ENSDART00000166549
mchr1a
melanin-concentrating hormone receptor 1a
chr21_+_25221940 2.09 ENSDART00000108972
sycn.1
syncollin, tandem duplicate 1

Network of associatons between targets according to the STRING database.

First level regulatory network of esrrd+esrrga_esrrb_esrra+esrrgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 20.8 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
2.7 8.1 GO:0051154 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
2.4 7.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
2.4 14.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
2.3 18.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
2.2 53.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.2 6.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.1 27.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.0 5.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.7 17.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.7 41.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.4 22.6 GO:0048769 sarcomerogenesis(GO:0048769)
1.3 4.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.3 3.9 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
1.2 4.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
1.1 3.2 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
1.0 3.0 GO:0098543 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
1.0 9.8 GO:0006108 malate metabolic process(GO:0006108)
1.0 4.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.0 7.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.9 8.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.9 2.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.9 3.7 GO:0006740 NADPH regeneration(GO:0006740)
0.9 2.6 GO:0030237 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.8 27.8 GO:0050821 protein stabilization(GO:0050821)
0.8 14.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.8 4.5 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.7 2.9 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.7 2.2 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.7 2.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.7 2.6 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.6 2.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.6 2.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 1.7 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.5 3.8 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.5 1.6 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.5 2.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 2.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.5 3.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 4.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.5 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.5 3.4 GO:0030728 ovulation(GO:0030728)
0.5 13.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.5 12.1 GO:0030168 platelet activation(GO:0030168)
0.5 1.8 GO:0006844 acyl carnitine transport(GO:0006844)
0.5 12.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.4 1.8 GO:0006531 aspartate metabolic process(GO:0006531)
0.4 1.2 GO:0006089 lactate metabolic process(GO:0006089)
0.4 2.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 1.2 GO:0009750 response to fructose(GO:0009750)
0.4 1.2 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.4 2.4 GO:0006574 valine catabolic process(GO:0006574)
0.4 1.9 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.4 1.4 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 1.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 1.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 3.6 GO:0016486 peptide hormone processing(GO:0016486)
0.3 0.9 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 8.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.3 1.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 5.4 GO:0006119 oxidative phosphorylation(GO:0006119)
0.3 2.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 5.0 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 7.1 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.2 6.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 5.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.2 5.9 GO:0021884 forebrain neuron development(GO:0021884)
0.2 0.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 2.3 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 0.9 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.2 0.7 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 6.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 2.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 1.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 1.4 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 3.4 GO:0016203 muscle attachment(GO:0016203)
0.2 1.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.5 GO:0007567 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.2 0.4 GO:0002513 tolerance induction(GO:0002507) tolerance induction to self antigen(GO:0002513)
0.2 0.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.2 0.5 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 0.7 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 3.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 2.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 1.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 2.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 0.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 3.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.2 6.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.0 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.2 3.4 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.2 2.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.2 0.6 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.2 1.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.3 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 1.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 3.0 GO:0002027 regulation of heart rate(GO:0002027)
0.1 7.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 1.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 2.5 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.8 GO:0006788 heme oxidation(GO:0006788)
0.1 4.3 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.6 GO:0043029 T cell homeostasis(GO:0043029)
0.1 1.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 2.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 11.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.3 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 2.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 2.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 2.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 11.8 GO:0006979 response to oxidative stress(GO:0006979)
0.1 13.2 GO:0006936 muscle contraction(GO:0006936)
0.1 0.8 GO:0035094 response to nicotine(GO:0035094)
0.1 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.8 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 8.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 4.9 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 2.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 4.4 GO:0051592 response to calcium ion(GO:0051592)
0.1 0.6 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 1.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 6.2 GO:0009615 response to virus(GO:0009615)
0.1 3.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.4 GO:0035889 otolith tethering(GO:0035889)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.7 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.6 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 21.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.2 GO:0060074 synapse maturation(GO:0060074)
0.1 2.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.3 GO:0060343 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.1 1.0 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 1.2 GO:0006415 translational termination(GO:0006415)
0.1 1.2 GO:0015671 oxygen transport(GO:0015671)
0.1 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.5 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 1.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.6 GO:0003139 secondary heart field specification(GO:0003139)
0.1 0.8 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.8 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 1.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 2.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.6 GO:0048919 posterior lateral line neuromast development(GO:0048919)
0.0 1.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 6.5 GO:0055001 muscle cell development(GO:0055001)
0.0 1.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.6 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 1.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 1.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.5 GO:0022900 electron transport chain(GO:0022900)
0.0 0.8 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 1.0 GO:0001707 mesoderm formation(GO:0001707)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.2 GO:0042471 ear morphogenesis(GO:0042471)
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.0 1.9 GO:0007283 spermatogenesis(GO:0007283)
0.0 1.3 GO:0001666 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 0.9 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.3 GO:0021782 glial cell development(GO:0021782)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0007129 synapsis(GO:0007129)
0.0 0.3 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.1 GO:0031349 positive regulation of defense response(GO:0031349) positive regulation of innate immune response(GO:0045089)
0.0 1.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.0 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 20.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.4 14.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.3 18.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
2.0 5.9 GO:1902560 GMP reductase complex(GO:1902560)
1.8 20.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.7 17.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.4 21.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.1 75.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
1.1 12.3 GO:0061617 MICOS complex(GO:0061617)
1.0 20.0 GO:0031430 M band(GO:0031430)
0.7 11.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.6 1.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 2.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.4 51.8 GO:0016459 myosin complex(GO:0016459)
0.4 1.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 1.7 GO:0070062 extracellular exosome(GO:0070062)
0.3 3.9 GO:0070187 telosome(GO:0070187)
0.3 2.5 GO:0070449 elongin complex(GO:0070449)
0.2 1.7 GO:0035253 ciliary rootlet(GO:0035253)
0.2 0.9 GO:0097268 cytoophidium(GO:0097268)
0.2 1.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.7 GO:0097189 apoptotic body(GO:0097189)
0.2 15.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 48.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 2.9 GO:0005922 connexon complex(GO:0005922)
0.2 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 2.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.2 2.9 GO:0030315 T-tubule(GO:0030315)
0.2 14.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 3.6 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 0.6 GO:0031673 H zone(GO:0031673)
0.1 1.9 GO:0042627 chylomicron(GO:0042627)
0.1 8.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.2 GO:0031526 brush border membrane(GO:0031526)
0.1 7.1 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.7 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 12.5 GO:0030017 sarcomere(GO:0030017)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 3.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 9.4 GO:0005882 intermediate filament(GO:0005882)
0.1 12.1 GO:0005840 ribosome(GO:0005840)
0.1 2.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.1 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 47.1 GO:0005739 mitochondrion(GO:0005739)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.1 GO:0043186 P granule(GO:0043186)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.2 GO:0016605 PML body(GO:0016605)
0.1 3.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 1.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 52.6 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 11.9 GO:0000785 chromatin(GO:0000785)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0005903 brush border(GO:0005903)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0098862 cluster of actin-based cell projections(GO:0098862)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 19.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 12.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 26.9 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
4.2 33.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.6 14.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
2.9 14.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.8 19.6 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
2.3 18.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.1 8.5 GO:0016842 amidine-lyase activity(GO:0016842)
2.0 5.9 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
1.9 54.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.8 20.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.2 1.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.1 3.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
1.1 7.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.1 23.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.0 4.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.0 3.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.9 3.7 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.8 11.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.8 3.8 GO:0051903 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.7 2.9 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.7 2.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.7 3.4 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.6 2.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.6 6.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 2.4 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.5 4.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.5 2.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.5 13.0 GO:0009055 electron carrier activity(GO:0009055)
0.5 3.7 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.5 2.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.5 1.8 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.4 4.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.4 1.8 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 2.6 GO:0070330 aromatase activity(GO:0070330)
0.4 2.4 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.4 1.2 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.4 1.9 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.4 1.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 5.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 2.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.4 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.4 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.3 5.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.3 3.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 9.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 4.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.3 0.8 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.3 7.7 GO:0030165 PDZ domain binding(GO:0030165)
0.2 0.7 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 1.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 2.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 1.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 1.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 0.9 GO:0003883 CTP synthase activity(GO:0003883)
0.2 3.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 4.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 4.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 1.6 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 0.6 GO:0042806 fucose binding(GO:0042806)
0.2 1.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 53.0 GO:0003774 motor activity(GO:0003774)
0.2 2.9 GO:0005243 gap junction channel activity(GO:0005243)
0.2 5.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 4.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.6 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 1.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 2.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.5 GO:0004990 oxytocin receptor activity(GO:0004990)
0.2 8.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.4 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 11.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 1.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 1.9 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 1.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 4.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.0 GO:0030552 cAMP binding(GO:0030552)
0.2 1.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 2.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 9.4 GO:0005507 copper ion binding(GO:0005507)
0.1 0.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 5.0 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 0.6 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 1.3 GO:0015250 water channel activity(GO:0015250)
0.1 10.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 6.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.2 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.0 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.8 GO:0032052 bile acid binding(GO:0032052)
0.1 3.2 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.1 1.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.7 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.6 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.3 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 7.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 6.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.2 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 1.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 2.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 9.3 GO:0042277 peptide binding(GO:0042277)
0.1 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.5 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.6 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 9.5 GO:0005179 hormone activity(GO:0005179)
0.1 0.7 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 13.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.4 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 11.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.8 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.1 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 3.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 5.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.8 GO:0051087 chaperone binding(GO:0051087)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 12.5 GO:0051015 actin filament binding(GO:0051015)
0.0 1.7 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 2.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 2.3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.3 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.5 GO:0031720 haptoglobin binding(GO:0031720)
0.0 5.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 18.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 1.7 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 36.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 5.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 7.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 1.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 45.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.5 85.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.8 12.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 10.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.7 13.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.6 6.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.6 0.6 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.6 8.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.6 5.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.5 5.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 3.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 4.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 4.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 8.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 4.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 1.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 9.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 1.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 4.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER