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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for ets2

Z-value: 0.98

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Transcription factors associated with ets2

Gene Symbol Gene ID Gene Info
ets2
ENSDARG00000103980 v-ets avian erythroblastosis virus E26 oncogene homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ets2dr11_v1_chr10_+_187760_1877640.372.4e-04Click!

Activity profile of ets2 motif

Sorted Z-values of ets2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25765734 10.83 ENSDART00000021664
cldnb
claudin b
chr15_-_29598679 10.53 ENSDART00000155153
si:ch211-207n23.2
si:ch211-207n23.2
chr1_-_37383539 9.76 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr8_+_3379815 9.74 ENSDART00000155995
FUT9 (1 of many)
zgc:136963
chr15_-_2652640 7.12 ENSDART00000146094
cldnf
claudin f
chr16_+_38201840 6.97 ENSDART00000044971
myo1eb
myosin IE, b
chr11_+_25278772 6.46 ENSDART00000188630
cyldb
cylindromatosis (turban tumor syndrome), b
chr1_-_37383741 6.37 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr5_-_55981288 6.24 ENSDART00000146616
si:dkey-189h5.6
si:dkey-189h5.6
chr15_-_29598444 6.13 ENSDART00000154847
si:ch211-207n23.2
si:ch211-207n23.2
chr8_-_31107537 6.09 ENSDART00000098925
vgll4l
vestigial like 4 like
chr6_+_112579 5.96 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr15_+_15779184 5.94 ENSDART00000156902
si:ch211-33e4.2
si:ch211-33e4.2
chr6_-_40657653 5.86 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr21_+_30351256 5.66 ENSDART00000078341
foxi3a
forkhead box I3a
chr16_+_35401543 5.66 ENSDART00000171608
rab42b
RAB42, member RAS oncogene family
chr14_-_14643190 5.65 ENSDART00000167119
znf185
zinc finger protein 185 with LIM domain
chr3_-_27647845 5.58 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr5_+_56026031 5.48 ENSDART00000050970
fzd9a
frizzled class receptor 9a
chr18_+_36631923 5.38 ENSDART00000098980
znf296
zinc finger protein 296
chr22_-_1079773 5.24 ENSDART00000136668
si:ch1073-15f12.3
si:ch1073-15f12.3
chr17_-_2039511 5.21 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr12_+_22576404 5.11 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr16_-_25233515 5.03 ENSDART00000058943
zgc:110182
zgc:110182
chr21_+_30794351 4.94 ENSDART00000139486
zgc:158225
zgc:158225
chr6_-_49063085 4.91 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr14_+_20911310 4.79 ENSDART00000160318
lygl2
lysozyme g-like 2
chr7_-_34262080 4.75 ENSDART00000183246
si:ch211-98n17.5
si:ch211-98n17.5
chr9_-_23807032 4.64 ENSDART00000027443
esyt3
extended synaptotagmin-like protein 3
chr13_+_30696286 4.44 ENSDART00000192411
cxcl18a.1
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr4_-_992063 4.26 ENSDART00000181630
ENSDART00000183898
ENSDART00000160902
naga
N-acetylgalactosaminidase, alpha
chr10_+_8875195 4.24 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr1_-_8653385 4.17 ENSDART00000193041
actb1
actin, beta 1
chr1_-_44796531 4.13 ENSDART00000144511
si:dkey-9i23.6
si:dkey-9i23.6
chr10_+_3127809 4.06 ENSDART00000185500
ckmt2a
creatine kinase, mitochondrial 2a (sarcomeric)
chr10_-_8046764 4.03 ENSDART00000099031
zgc:136254
zgc:136254
chr7_-_57637779 4.00 ENSDART00000028017
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr22_+_19220459 3.99 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr4_+_842010 3.96 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr21_+_28747069 3.86 ENSDART00000014058
zgc:100829
zgc:100829
chr7_-_53117131 3.83 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr15_-_3277635 3.77 ENSDART00000189094
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr3_+_59880317 3.74 ENSDART00000166922
ENSDART00000108647
alyref
Aly/REF export factor
chr9_-_105135 3.68 ENSDART00000180126
FQ377903.3

chr15_+_20239141 3.66 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr8_+_44783424 3.63 ENSDART00000025875
si:ch1073-459j12.1
si:ch1073-459j12.1
chr17_-_24890843 3.60 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
gale
UDP-galactose-4-epimerase
chr12_-_49149800 3.59 ENSDART00000182290
bub3
BUB3 mitotic checkpoint protein
chr4_+_12966640 3.58 ENSDART00000113357
vhll
von Hippel-Lindau tumor suppressor like
chr17_-_21368775 3.58 ENSDART00000058027
shtn1
shootin 1
chr11_+_44135351 3.56 ENSDART00000182914
FO704721.1

chr19_-_48312109 3.55 ENSDART00000161103
si:ch73-359m17.9
si:ch73-359m17.9
chr1_-_48933 3.54 ENSDART00000171162
ildr1a
immunoglobulin-like domain containing receptor 1a
chr4_+_7698862 3.53 ENSDART00000009909
elk3
ELK3, ETS-domain protein
chr5_+_6672870 3.50 ENSDART00000126598
pxna
paxillin a
chr20_-_35554451 3.45 ENSDART00000189085
adgrf7
adhesion G protein-coupled receptor F7
chr9_+_13999620 3.41 ENSDART00000143229
cd28l
cd28-like molecule
chr21_+_27448856 3.40 ENSDART00000100784
cfbl
complement factor b-like
chr25_-_13553055 3.31 ENSDART00000103831
ENSDART00000139290
ano10b
anoctamin 10b
chr13_-_25767210 3.29 ENSDART00000131792
pdlim1
PDZ and LIM domain 1 (elfin)
chr21_+_28747236 3.27 ENSDART00000137874
zgc:100829
zgc:100829
chr15_-_43284021 3.24 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_+_26667475 3.23 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
si:ch73-52f15.5
chr10_+_2582254 3.23 ENSDART00000016103
nxnl2
nucleoredoxin like 2
chr19_+_3849378 3.18 ENSDART00000166218
ENSDART00000159228
oscp1a
organic solute carrier partner 1a
chr13_-_36582341 3.15 ENSDART00000137335
lgals3a
lectin, galactoside binding soluble 3a
chr13_-_33321058 3.15 ENSDART00000112084
si:dkey-71p21.13
si:dkey-71p21.13
chr19_-_1855368 3.14 ENSDART00000029646
rplp1
ribosomal protein, large, P1
chr7_+_73295890 3.13 ENSDART00000174331
ENSDART00000174250
CABZ01083442.1

chr9_-_33062891 3.12 ENSDART00000161182
si:ch211-125e6.5
si:ch211-125e6.5
chr16_-_39570832 3.11 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr14_-_9128919 3.10 ENSDART00000108641
sh2d1ab
SH2 domain containing 1A duplicate b
chr19_+_43297546 3.09 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr4_+_76671012 3.06 ENSDART00000005585
ms4a17a.2
membrane-spanning 4-domains, subfamily A, member 17a.2
chr18_+_25653599 3.04 ENSDART00000007856
fkbp16
FK506 binding protein 16
chr21_+_261490 3.03 ENSDART00000177919
jak2a
Janus kinase 2a
chr22_-_193234 3.02 ENSDART00000131067
fbxo42
F-box protein 42
chr14_-_40797117 2.99 ENSDART00000122369
elf1
E74-like ETS transcription factor 1
chr18_+_3140682 2.98 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr3_-_16537441 2.97 ENSDART00000080749
ENSDART00000133824
eps8l1
eps8-like1
chr9_-_33081781 2.96 ENSDART00000165748
zgc:172053
zgc:172053
chr13_-_34858500 2.90 ENSDART00000184843
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr4_+_76787274 2.90 ENSDART00000156344
si:ch73-56d11.3
si:ch73-56d11.3
chr2_+_48282590 2.86 ENSDART00000035338
lpar5a
lysophosphatidic acid receptor 5a
chr11_+_22109887 2.86 ENSDART00000122136
MDFI
si:dkey-91m3.1
chr5_-_42272517 2.85 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr10_-_8053385 2.80 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr4_+_7677318 2.80 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr22_+_20710434 2.79 ENSDART00000135521
peak3
PEAK family member 3
chr15_+_12436220 2.75 ENSDART00000169894
tmprss4a
transmembrane protease, serine 4a
chr23_+_27675581 2.75 ENSDART00000127198
rps26
ribosomal protein S26
chr9_-_33081978 2.72 ENSDART00000100918
zgc:172053
zgc:172053
chr21_-_25295087 2.72 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr8_-_50135492 2.69 ENSDART00000149398
si:ch73-132k15.2
si:ch73-132k15.2
chr25_+_7598778 2.66 ENSDART00000104701
FO704779.1

chr20_+_54304800 2.62 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr6_-_49215790 2.62 ENSDART00000103376
ENSDART00000132347
ENSDART00000132131
ENSDART00000143252
ENSDART00000065033
ngfb
nerve growth factor b (beta polypeptide)
chr7_+_67467702 2.62 ENSDART00000168460
ENSDART00000170322
rpl13
ribosomal protein L13
chr9_-_42484444 2.61 ENSDART00000048320
ENSDART00000047653
tfpia
tissue factor pathway inhibitor a
chr3_-_36364903 2.58 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr17_+_45395846 2.57 ENSDART00000058793
nenf
neudesin neurotrophic factor
chr7_-_51639699 2.55 ENSDART00000128917
rps4x
ribosomal protein S4, X-linked
chr1_+_36674584 2.55 ENSDART00000186772
ENSDART00000192274
ednraa
endothelin receptor type Aa
chr8_+_25629941 2.55 ENSDART00000186925
wasa
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr8_-_4586696 2.54 ENSDART00000143511
ENSDART00000134324
gp1bb
glycoprotein Ib (platelet), beta polypeptide
chr5_-_32336613 2.54 ENSDART00000139732
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr1_+_59314675 2.54 ENSDART00000161872
ENSDART00000160658
ENSDART00000169792
ENSDART00000160735
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr12_-_44122412 2.53 ENSDART00000169094
si:ch73-329n5.3
si:ch73-329n5.3
chr22_+_5687615 2.51 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr10_+_9553935 2.47 ENSDART00000028855
si:ch211-243g18.2
si:ch211-243g18.2
chr20_+_19175031 2.47 ENSDART00000138028
blk
BLK proto-oncogene, Src family tyrosine kinase
chr3_-_3723494 2.47 ENSDART00000056023
si:dkey-217f16.1
si:dkey-217f16.1
chr7_-_66133786 2.44 ENSDART00000154961
btbd10b
BTB (POZ) domain containing 10b
chr11_+_18037729 2.43 ENSDART00000111624
zgc:175135
zgc:175135
chr9_-_56232296 2.43 ENSDART00000149554
rpl31
ribosomal protein L31
chr7_+_26545502 2.40 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr3_+_43826018 2.40 ENSDART00000166197
ENSDART00000165145
litaf
lipopolysaccharide-induced TNF factor
chr1_-_40735381 2.39 ENSDART00000093269
zgc:153642
zgc:153642
chr5_+_50953240 2.39 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr16_+_38277339 2.38 ENSDART00000085143
bnipl
BCL2 interacting protein like
chr1_-_18772241 2.38 ENSDART00000147645
ENSDART00000133194
ENSDART00000147525
ENSDART00000191493
tbc1d1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr14_-_5678457 2.37 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr6_+_49881864 2.33 ENSDART00000075040
tubb1
tubulin, beta 1 class VI
chr5_-_54712159 2.33 ENSDART00000149207
ccnb1
cyclin B1
chr1_-_18848955 2.31 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr20_+_54079341 2.30 ENSDART00000060444
rps29
ribosomal protein S29
chr18_+_27598755 2.30 ENSDART00000193808
cd82b
CD82 molecule b
chr5_-_37047147 2.30 ENSDART00000097712
ENSDART00000158974
ftr99
finTRIM family, member 99
chr12_-_49168398 2.29 ENSDART00000186608
FO704624.1

chr10_-_8053753 2.29 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr3_-_34528306 2.28 ENSDART00000023039
sept9a
septin 9a
chr11_+_18157260 2.28 ENSDART00000144659
zgc:173545
zgc:173545
chr19_+_43523690 2.26 ENSDART00000113031
wasf2
WAS protein family, member 2
chr13_+_15933168 2.25 ENSDART00000131390
fignl1
fidgetin-like 1
chr11_-_18384534 2.20 ENSDART00000156499
prkcdb
protein kinase C, delta b
chr13_+_28580357 2.18 ENSDART00000007211
wbp1la
WW domain binding protein 1-like a
chr23_-_45022681 2.18 ENSDART00000102640
ctc1
CTS telomere maintenance complex component 1
chr6_-_1223551 2.17 ENSDART00000182112
CABZ01063034.1

chr20_+_54312970 2.16 ENSDART00000024598
ENSDART00000193172
zp2.5
zona pellucida glycoprotein 2, tandem duplicate 5
chr20_+_54290356 2.15 ENSDART00000173347
zp2.2
zona pellucida glycoprotein 2, tandem duplicate 2
chr5_+_46277593 2.14 ENSDART00000045598
zgc:110626
zgc:110626
chr14_+_34501245 2.14 ENSDART00000131424
lcp2b
lymphocyte cytosolic protein 2b
chr16_-_10316359 2.13 ENSDART00000104025
flot1b
flotillin 1b
chr11_+_18183220 2.13 ENSDART00000113468
LO018315.10

chr13_-_280827 2.11 ENSDART00000144819
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr19_+_1873059 2.10 ENSDART00000145246
snrpd1
small nuclear ribonucleoprotein D1 polypeptide
chr25_+_5068442 2.10 ENSDART00000097522
parvg
parvin, gamma
chr15_+_436776 2.07 ENSDART00000008504
med17
mediator complex subunit 17
chr19_+_48024457 2.07 ENSDART00000163823
kpnb1
karyopherin (importin) beta 1
chr13_-_22961605 2.05 ENSDART00000143112
ENSDART00000057641
tspan15
tetraspanin 15
chr9_-_9419704 2.05 ENSDART00000138996
si:ch211-214p13.9
si:ch211-214p13.9
chr14_-_897874 2.04 ENSDART00000167395
rgs14a
regulator of G protein signaling 14a
chr3_+_56574623 2.02 ENSDART00000130877
rac1b
Rac family small GTPase 1b
chr1_+_26622214 2.01 ENSDART00000182040
ENSDART00000152643
coro2a
coronin, actin binding protein, 2A
chr20_+_54309148 2.00 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr7_-_24112484 2.00 ENSDART00000111923
ajuba
ajuba LIM protein
chr3_-_45777226 1.98 ENSDART00000192849
h3f3b.1
H3 histone, family 3B.1
chr20_-_26937453 1.97 ENSDART00000139756
ftr97
finTRIM family, member 97
chr11_+_18053333 1.96 ENSDART00000075750
zgc:175135
zgc:175135
chr1_+_38142715 1.95 ENSDART00000079928
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr4_-_149334 1.95 ENSDART00000163280
tbk1
TANK-binding kinase 1
chr19_+_47476908 1.93 ENSDART00000157886
zgc:114119
zgc:114119
chr11_+_141504 1.93 ENSDART00000086166
NCKAP1L
zgc:172352
chr21_-_3796461 1.92 ENSDART00000021976
nsa2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr5_+_40837539 1.92 ENSDART00000188279
si:dkey-3h3.3
si:dkey-3h3.3
chr20_+_54299419 1.92 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr14_-_52408307 1.90 ENSDART00000167045
ENSDART00000162719
ENSDART00000160293
polr2b
polymerase (RNA) II (DNA directed) polypeptide B
chr17_+_132555 1.89 ENSDART00000158159
zgc:77287
zgc:77287
chr22_-_22337382 1.88 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr3_-_16719244 1.88 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr10_-_20650302 1.88 ENSDART00000142028
ENSDART00000064662
rassf2b
Ras association (RalGDS/AF-6) domain family member 2b
chr14_+_23709543 1.87 ENSDART00000136909
gnpda1
glucosamine-6-phosphate deaminase 1
chr9_+_31752628 1.87 ENSDART00000060054
itgbl1
integrin, beta-like 1
chr3_+_23742868 1.87 ENSDART00000153512
hoxb3a
homeobox B3a
chr4_+_77957611 1.85 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr16_-_40426837 1.85 ENSDART00000193690
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr3_-_61116258 1.84 ENSDART00000009194
ENSDART00000156978
aimp2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr7_-_54098631 1.83 ENSDART00000165499
rps17
ribosomal protein S17
chr16_+_13965923 1.83 ENSDART00000103857
zgc:162509
zgc:162509
chr7_-_26603743 1.82 ENSDART00000099003
plscr3b
phospholipid scramblase 3b
chr9_+_13985567 1.82 ENSDART00000102296
cd28
CD28 molecule
chr15_+_11883804 1.81 ENSDART00000163255
gpr184
G protein-coupled receptor 184
chr25_-_37465064 1.81 ENSDART00000186128
zgc:158366
zgc:158366
chr19_-_79202 1.80 ENSDART00000166009
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr12_+_763051 1.80 ENSDART00000152579
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr19_-_43757568 1.79 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr11_+_18130300 1.79 ENSDART00000169146
zgc:175135
zgc:175135
chr23_+_9560797 1.79 ENSDART00000180014
adrm1
adhesion regulating molecule 1
chr8_+_21254192 1.79 ENSDART00000167718
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr7_-_66877058 1.78 ENSDART00000155954
adma
adrenomedullin a
chr2_+_22495274 1.78 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 VRAC subunit Da
chr9_+_48819280 1.77 ENSDART00000112555
spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr23_-_19682971 1.77 ENSDART00000048891
zgc:193598
zgc:193598
chr5_+_21181047 1.76 ENSDART00000088506
arhgap25
Rho GTPase activating protein 25
chr16_-_9802449 1.76 ENSDART00000081208
tapbpl
TAP binding protein (tapasin)-like
chr2_+_13069168 1.76 ENSDART00000192832
prkag2b
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr11_+_8129536 1.76 ENSDART00000158112
ENSDART00000011183
prkacba
protein kinase, cAMP-dependent, catalytic, beta a
chr6_+_39360377 1.75 ENSDART00000028260
ENSDART00000151322
zgc:77517
zgc:77517
chr19_+_3206263 1.74 ENSDART00000020344
zgc:86598
zgc:86598
chr8_-_17184482 1.72 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ets2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.4 5.7 GO:0009957 epidermal cell fate specification(GO:0009957)
1.3 5.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
1.3 3.8 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.9 4.3 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.8 2.5 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.8 2.5 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.8 4.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.7 3.6 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.7 2.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.7 2.0 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.6 6.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.6 2.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.6 4.3 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.6 3.6 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.6 2.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.5 2.5 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 1.5 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.5 2.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 1.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.5 2.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 2.5 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.4 2.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.4 1.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.4 8.6 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.4 1.9 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.4 17.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3 2.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.7 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.3 1.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 10.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 4.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 2.5 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.3 2.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 1.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 4.1 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 1.6 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.3 0.9 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.3 4.3 GO:0061055 myotome development(GO:0061055)
0.3 1.1 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.3 2.8 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 1.1 GO:0046324 regulation of glucose import(GO:0046324)
0.3 0.8 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.3 0.8 GO:0035046 pronuclear migration(GO:0035046)
0.3 4.1 GO:0043248 proteasome assembly(GO:0043248)
0.3 1.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 2.9 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 1.2 GO:0043111 replication fork arrest(GO:0043111)
0.2 2.6 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.2 0.7 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 0.9 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 2.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 0.8 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.2 1.5 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 0.6 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.2 6.3 GO:0051014 actin filament severing(GO:0051014)
0.2 1.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.2 1.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.2 7.0 GO:0003094 glomerular filtration(GO:0003094)
0.2 5.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 1.5 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2 0.7 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.2 1.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 2.6 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.2 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 1.5 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 2.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.4 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 2.2 GO:0008354 germ cell migration(GO:0008354)
0.1 1.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 3.1 GO:0006301 postreplication repair(GO:0006301)
0.1 7.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.7 GO:0000012 single strand break repair(GO:0000012)
0.1 2.5 GO:0030183 B cell differentiation(GO:0030183)
0.1 5.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.9 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 1.5 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.2 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 3.4 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 4.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.4 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1 0.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.9 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 3.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.6 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0060631 regulation of meiosis I(GO:0060631)
0.1 1.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.6 GO:0007405 neuroblast proliferation(GO:0007405)
0.1 7.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.3 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 6.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 3.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0010039 response to iron ion(GO:0010039)
0.1 1.8 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.5 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 1.7 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.7 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.4 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.6 GO:0031179 peptide modification(GO:0031179)
0.1 1.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.5 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 1.3 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.1 1.5 GO:0097320 membrane tubulation(GO:0097320)
0.1 3.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.0 GO:0035476 angioblast cell migration(GO:0035476)
0.1 5.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.3 GO:0014005 microglia development(GO:0014005)
0.1 0.5 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 3.7 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 2.6 GO:0030217 T cell differentiation(GO:0030217)
0.1 4.8 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.8 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.8 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.4 GO:0061056 sclerotome development(GO:0061056)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.7 GO:0046688 response to copper ion(GO:0046688)
0.0 2.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 3.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.8 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 2.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 2.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.0 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.1 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 3.3 GO:0006401 RNA catabolic process(GO:0006401)
0.0 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.4 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:1901655 cellular response to ketone(GO:1901655)
0.0 3.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.0 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.2 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.4 GO:0060021 palate development(GO:0060021)
0.0 0.8 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 1.5 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 5.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.6 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.0 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.9 GO:0007596 blood coagulation(GO:0007596)
0.0 6.9 GO:0006412 translation(GO:0006412)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0051597 release of cytochrome c from mitochondria(GO:0001836) response to methylmercury(GO:0051597)
0.0 0.9 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.2 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.9 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 3.5 GO:0045087 innate immune response(GO:0045087)
0.0 1.0 GO:0010469 regulation of receptor activity(GO:0010469)
0.0 0.9 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.9 GO:0001754 eye photoreceptor cell differentiation(GO:0001754)
0.0 1.6 GO:0051216 cartilage development(GO:0051216)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0034709 methylosome(GO:0034709)
0.9 3.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.8 4.2 GO:0097433 dense body(GO:0097433)
0.8 2.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.7 2.9 GO:0019815 B cell receptor complex(GO:0019815)
0.7 2.2 GO:1990879 CST complex(GO:1990879)
0.6 2.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.6 3.6 GO:0030891 VCB complex(GO:0030891)
0.6 1.7 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.5 4.3 GO:0001772 immunological synapse(GO:0001772)
0.5 2.1 GO:0016600 flotillin complex(GO:0016600)
0.4 2.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 2.0 GO:1990071 TRAPPII protein complex(GO:1990071)
0.4 0.8 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.4 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.1 GO:0010369 chromocenter(GO:0010369)
0.3 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 0.9 GO:0070578 RISC-loading complex(GO:0070578)
0.3 3.6 GO:0044295 axonal growth cone(GO:0044295)
0.3 3.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 2.1 GO:0070847 core mediator complex(GO:0070847)
0.3 1.8 GO:0031262 Ndc80 complex(GO:0031262)
0.3 2.9 GO:0005688 U6 snRNP(GO:0005688)
0.3 2.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.3 2.6 GO:0031526 brush border membrane(GO:0031526)
0.3 7.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.3 GO:1990923 PET complex(GO:1990923)
0.2 1.2 GO:0031298 replication fork protection complex(GO:0031298)
0.2 1.7 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 0.6 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.2 0.8 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 3.8 GO:0030057 desmosome(GO:0030057)
0.2 1.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 1.0 GO:0070390 transcription export complex 2(GO:0070390)
0.2 9.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 2.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 9.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 2.3 GO:0031209 SCAR complex(GO:0031209)
0.1 7.0 GO:0005902 microvillus(GO:0005902)
0.1 0.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 16.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.0 GO:0000796 condensin complex(GO:0000796)
0.1 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 12.6 GO:0000776 kinetochore(GO:0000776)
0.1 0.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 16.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 1.8 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 4.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.1 1.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.4 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 0.3 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 10.2 GO:0005925 focal adhesion(GO:0005925)
0.1 5.8 GO:0030027 lamellipodium(GO:0030027)
0.1 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 2.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 5.5 GO:0005604 basement membrane(GO:0005604)
0.1 1.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 1.0 GO:0098844 dendritic spine head(GO:0044327) postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 7.3 GO:0005764 lysosome(GO:0005764)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 6.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 11.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.8 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 4.3 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.2 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.6 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.0 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 6.2 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 30.0 GO:0005576 extracellular region(GO:0005576)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0030426 growth cone(GO:0030426)
0.0 1.7 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0004557 alpha-galactosidase activity(GO:0004557)
1.2 6.1 GO:0001223 transcription coactivator binding(GO:0001223)
1.2 3.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
1.2 4.8 GO:0003796 lysozyme activity(GO:0003796)
0.9 4.3 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.9 2.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.8 4.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.6 6.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.6 3.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 1.7 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.5 0.5 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 1.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.5 3.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.5 7.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.5 0.9 GO:0070883 pre-miRNA binding(GO:0070883)
0.5 5.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 1.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 3.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.4 1.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.4 1.1 GO:0070051 fibrinogen binding(GO:0070051)
0.4 2.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.4 2.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 1.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 5.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 1.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 4.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 6.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 0.8 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.3 2.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 0.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.3 1.0 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.3 2.5 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 2.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.6 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.2 1.5 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.2 3.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 2.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 1.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 3.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 2.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.6 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 0.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 6.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.9 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 1.4 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 8.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 1.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 1.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 3.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 1.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 1.3 GO:0034584 piRNA binding(GO:0034584)
0.2 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 2.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 6.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 2.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.9 GO:0035198 miRNA binding(GO:0035198)
0.1 1.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 20.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.7 GO:0019809 spermidine binding(GO:0019809)
0.1 0.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 8.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.4 GO:0008009 chemokine activity(GO:0008009)
0.1 1.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.4 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 4.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.2 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 9.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.0 GO:0051117 ATPase binding(GO:0051117)
0.1 1.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 2.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.8 GO:0016208 AMP binding(GO:0016208)
0.1 0.5 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 2.8 GO:0005178 integrin binding(GO:0005178)
0.1 1.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 6.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 16.7 GO:0051015 actin filament binding(GO:0051015)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 3.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 9.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 6.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.7 GO:0003779 actin binding(GO:0003779)
0.0 0.8 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 1.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 2.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 4.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 7.4 PID P73PATHWAY p73 transcription factor network
0.1 3.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 3.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.1 PID ATR PATHWAY ATR signaling pathway
0.1 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 6.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5 2.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.4 2.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 7.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.3 2.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 10.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.3 4.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.3 4.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 1.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 1.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 9.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 2.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 1.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 9.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 4.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 0.3 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 1.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 2.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation