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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for eve1+evx1

Z-value: 0.70

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Transcription factors associated with eve1+evx1

Gene Symbol Gene ID Gene Info
eve1
ENSDARG00000056012 even-skipped-like1
evx1
ENSDARG00000099365 even-skipped homeobox 1
evx1
ENSDARG00000100087 even-skipped homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
evx1dr11_v1_chr19_-_19721556_19721556-0.431.2e-05Click!
eve1dr11_v1_chr3_-_23643751_236438300.151.6e-01Click!

Activity profile of eve1+evx1 motif

Sorted Z-values of eve1+evx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_2414063 13.49 ENSDART00000073621
zgc:152945
zgc:152945
chr3_+_1005059 9.97 ENSDART00000132460
zgc:172051
zgc:172051
chr10_+_21867307 9.79 ENSDART00000126629
cbln17
cerebellin 17
chr16_-_54455573 9.67 ENSDART00000075275
pklr
pyruvate kinase L/R
chr20_-_40755614 8.01 ENSDART00000061247
cx32.3
connexin 32.3
chr25_+_3327071 7.44 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr20_-_23426339 7.16 ENSDART00000004625
zar1
zygote arrest 1
chr21_+_25777425 6.37 ENSDART00000021620
cldnd
claudin d
chr10_+_25726694 5.14 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr9_-_35633827 4.75 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr7_+_69019851 4.69 ENSDART00000162891
CABZ01057488.1

chr19_+_31585917 4.47 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr5_-_42904329 4.29 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr18_+_1837668 4.00 ENSDART00000164210
CABZ01079192.1

chr1_+_55758257 3.78 ENSDART00000139312
tecrb
trans-2,3-enoyl-CoA reductase b
chr21_-_19919020 3.68 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr19_-_18313303 3.57 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
si:dkey-208k4.2
chr2_-_15324837 3.57 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr17_-_23446760 3.45 ENSDART00000104715
pcgf5a
polycomb group ring finger 5a
chr16_-_42056137 3.17 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr11_-_45152702 3.02 ENSDART00000168066
afmid
arylformamidase
chr10_+_7709724 2.96 ENSDART00000097670
ggcx
gamma-glutamyl carboxylase
chr8_-_21372446 2.77 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr2_+_6253246 2.74 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr25_-_11378623 2.72 ENSDART00000166586
enc2
ectodermal-neural cortex 2
chr10_-_21362071 2.68 ENSDART00000125167
avd
avidin
chr3_+_13624815 2.67 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr6_+_28208973 2.60 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr10_-_21362320 2.45 ENSDART00000189789
avd
avidin
chr15_-_23793641 2.42 ENSDART00000122891
tmem97
transmembrane protein 97
chr2_-_57076687 2.41 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr6_-_40352215 2.36 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr3_+_17537352 2.30 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr24_+_1023839 2.29 ENSDART00000082526
zgc:111976
zgc:111976
chr10_+_36345176 2.07 ENSDART00000099397
or105-1
odorant receptor, family C, subfamily 105, member 1
chr10_-_44560165 2.00 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr1_-_47071979 1.97 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr15_+_29662401 1.92 ENSDART00000135540
nrip1a
nuclear receptor interacting protein 1a
chr2_-_50225411 1.91 ENSDART00000147117
ENSDART00000000042
mcm6l
MCM6 minichromosome maintenance deficient 6, like
chr20_+_41021054 1.76 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr8_-_21142550 1.72 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr25_-_25384045 1.62 ENSDART00000150631
zgc:123278
zgc:123278
chr2_+_31492662 1.56 ENSDART00000123495
cacnb2b
calcium channel, voltage-dependent, beta 2b
chr10_+_35257651 1.48 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr23_+_4646194 1.40 ENSDART00000092344
LO017700.1

chr12_-_24060358 1.38 ENSDART00000050831
chac2
ChaC, cation transport regulator homolog 2 (E. coli)
chr7_-_24046999 1.38 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr5_+_19314574 1.37 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr6_+_41200500 1.32 ENSDART00000000678
opn1mw4
opsin 1 (cone pigments), medium-wave-sensitive, 4
chr19_+_5543072 1.31 ENSDART00000082080
jupb
junction plakoglobin b
chr19_-_657439 1.30 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr8_-_27656765 1.19 ENSDART00000078491
mov10b.2
Moloney leukemia virus 10b, tandem duplicate 2
chr12_+_46582168 1.18 ENSDART00000189402
ush1gb
Usher syndrome 1Gb (autosomal recessive)
chr13_-_21660203 1.18 ENSDART00000100925
mxtx1
mix-type homeobox gene 1
chr17_-_23616626 1.18 ENSDART00000104730
ifit14
interferon-induced protein with tetratricopeptide repeats 14
chr23_+_33963619 1.13 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr7_+_30787903 1.13 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr10_+_17714866 1.05 ENSDART00000039969
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr19_+_15443540 1.04 ENSDART00000193355
lin28a
lin-28 homolog A (C. elegans)
chr22_-_12746539 1.03 ENSDART00000175374
plcd4a
phospholipase C, delta 4a
chr15_+_5360407 1.03 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr22_+_20427170 1.01 ENSDART00000136744
foxq2
forkhead box Q2
chr12_+_46582727 1.00 ENSDART00000149326
ush1gb
Usher syndrome 1Gb (autosomal recessive)
chr11_+_45323455 0.99 ENSDART00000189249
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr16_-_29458806 0.99 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr1_-_17715493 0.98 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr10_-_35257458 0.98 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr9_-_53666031 0.97 ENSDART00000126314
pcdh8
protocadherin 8
chr5_+_23242370 0.97 ENSDART00000051532
agtr2
angiotensin II receptor, type 2
chr10_-_41664427 0.96 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr16_+_35661331 0.95 ENSDART00000161725
map7d1a
MAP7 domain containing 1a
chr8_+_53423408 0.94 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr4_+_12612723 0.93 ENSDART00000133767
lmo3
LIM domain only 3
chr22_+_17205608 0.90 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr18_+_50461981 0.88 ENSDART00000158761
CU896640.1

chr7_-_1504382 0.87 ENSDART00000172770
si:zfos-405g10.4
si:zfos-405g10.4
chr12_-_32426685 0.85 ENSDART00000105574
enpp7.2
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2
chr25_+_35891342 0.83 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr15_-_16177603 0.81 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr10_+_518546 0.81 ENSDART00000128275
npffr1l3
neuropeptide FF receptor 1 like 3
chr8_-_50888806 0.77 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr16_+_35661771 0.77 ENSDART00000161393
map7d1a
MAP7 domain containing 1a
chr23_+_7548797 0.76 ENSDART00000006765
tm9sf4
transmembrane 9 superfamily protein member 4
chr18_-_12052132 0.76 ENSDART00000074361
zgc:110789
zgc:110789
chr8_-_39822917 0.74 ENSDART00000067843
zgc:162025
zgc:162025
chr2_-_21819421 0.73 ENSDART00000121586
chd7
chromodomain helicase DNA binding protein 7
chr11_+_31864921 0.72 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr9_-_24031461 0.71 ENSDART00000021218
rpe
ribulose-5-phosphate-3-epimerase
chr12_-_35830625 0.70 ENSDART00000180028
CU459056.1

chr10_+_3049636 0.70 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
rasgrf2a
Ras protein-specific guanine nucleotide-releasing factor 2a
chr21_-_27185915 0.70 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr10_+_40561692 0.70 ENSDART00000147757
taar18h
trace amine associated receptor 18h
chr11_+_35171406 0.69 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr20_+_37294112 0.69 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr13_+_38814521 0.69 ENSDART00000110976
col19a1
collagen, type XIX, alpha 1
chr23_-_33361425 0.66 ENSDART00000031638
slc48a1a
solute carrier family 48 (heme transporter), member 1a
chr21_+_1381276 0.66 ENSDART00000192907
TCF4
transcription factor 4
chr16_+_17389116 0.66 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr5_+_27137473 0.65 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr25_+_26923193 0.64 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr9_-_24030795 0.64 ENSDART00000144163
rpe
ribulose-5-phosphate-3-epimerase
chr23_-_20051369 0.64 ENSDART00000049836
bgnb
biglycan b
chr6_+_41191482 0.64 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr4_+_12612145 0.63 ENSDART00000181201
lmo3
LIM domain only 3
chr9_-_202805 0.63 ENSDART00000182260
CABZ01067557.1

chr23_-_31913231 0.63 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr21_+_10773522 0.63 ENSDART00000143257
znf532
zinc finger protein 532
chr25_-_6049339 0.60 ENSDART00000075184
snx1a
sorting nexin 1a
chr5_+_64732270 0.60 ENSDART00000134241
olfm1a
olfactomedin 1a
chr1_+_11977426 0.58 ENSDART00000103399
tspan5b
tetraspanin 5b
chr21_+_40292801 0.58 ENSDART00000174220
si:ch211-218m3.16
si:ch211-218m3.16
chr14_-_8625845 0.57 ENSDART00000054760
zgc:162144
zgc:162144
chr25_+_14507567 0.57 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr1_-_9195629 0.57 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr2_+_30464829 0.57 ENSDART00000181432
neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr2_-_32826108 0.56 ENSDART00000098834
prpf4ba
pre-mRNA processing factor 4Ba
chr24_-_25004553 0.56 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr15_+_5293785 0.55 ENSDART00000163157
or121-1
odorant receptor, family E, subfamily 121, member 1
chr15_+_5299404 0.54 ENSDART00000155410
or122-2
odorant receptor, family E, subfamily 122, member 2
chr10_-_11385155 0.54 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr21_+_43404945 0.53 ENSDART00000142234
frmd7
FERM domain containing 7
chr6_+_515181 0.52 ENSDART00000171374
CACNA1I (1 of many)
si:ch73-379f7.5
chr6_-_55585423 0.52 ENSDART00000157129
slc12a5a
solute carrier family 12 (potassium/chloride transporter), member 5a
chr4_+_52356485 0.51 ENSDART00000170639
zgc:173705
zgc:173705
chr2_-_10896745 0.51 ENSDART00000114609
cdcp2
CUB domain containing protein 2
chr2_-_16380283 0.50 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr16_+_31804590 0.49 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr15_+_31481939 0.49 ENSDART00000134306
or102-5
odorant receptor, family C, subfamily 102, member 5
chr23_-_19230627 0.49 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr12_-_33817114 0.48 ENSDART00000161265
twnk
twinkle mtDNA helicase
chr22_-_27709692 0.47 ENSDART00000172458
CR547131.1

chr2_+_30465102 0.47 ENSDART00000188404
neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr4_+_306036 0.47 ENSDART00000103659
msgn1
mesogenin 1
chr11_+_36231248 0.47 ENSDART00000131104
GPR62 (1 of many)
si:ch211-213o11.11
chr11_-_44876005 0.46 ENSDART00000192006
opn6a
opsin 6, group member a
chr7_-_17816478 0.46 ENSDART00000149403
ecsit
ECSIT signalling integrator
chr12_-_19007834 0.46 ENSDART00000153248
chadlb
chondroadherin-like b
chr23_+_44374041 0.46 ENSDART00000136056
ephb4b
eph receptor B4b
chr23_-_17484555 0.45 ENSDART00000187181
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr6_-_57655030 0.45 ENSDART00000155438
cbfa2t2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr21_-_44772738 0.44 ENSDART00000026178
kif4
kinesin family member 4
chr2_-_11258547 0.43 ENSDART00000165803
ENSDART00000193817
slc44a5a
solute carrier family 44, member 5a
chr9_-_54361357 0.43 ENSDART00000149813
rad50
RAD50 homolog, double strand break repair protein
chr20_+_22067337 0.43 ENSDART00000152636
clocka
clock circadian regulator a
chr19_+_40856807 0.42 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_-_32825917 0.42 ENSDART00000180409
prpf4ba
pre-mRNA processing factor 4Ba
chr10_+_41765944 0.42 ENSDART00000171484
rnf34b
ring finger protein 34b
chr23_-_44219902 0.41 ENSDART00000185874
zgc:158659
zgc:158659
chr17_+_21295132 0.41 ENSDART00000103845
eno4
enolase family member 4
chr9_-_19161982 0.40 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr1_+_51191049 0.40 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr7_-_39537292 0.40 ENSDART00000173965
otog
otogelin
chr6_+_41039166 0.38 ENSDART00000125659
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr7_-_27685365 0.38 ENSDART00000188342
calca
calcitonin/calcitonin-related polypeptide, alpha
chr21_-_3853204 0.37 ENSDART00000188829
st6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr15_+_9053059 0.37 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr3_+_22035863 0.36 ENSDART00000177169
cdc27
cell division cycle 27
chr22_-_881080 0.36 ENSDART00000185489
cept1b
choline/ethanolamine phosphotransferase 1b
chr7_-_17816175 0.36 ENSDART00000091272
ENSDART00000173757
ecsit
ECSIT signalling integrator
chr18_+_9615147 0.35 ENSDART00000160284
pclob
piccolo presynaptic cytomatrix protein b
chr6_+_9870192 0.35 ENSDART00000150894
MPP4 (1 of many)
si:ch211-222n4.6
chr6_+_39232245 0.33 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr21_+_34814444 0.33 ENSDART00000161816
wdr55
WD repeat domain 55
chr21_-_18993110 0.32 ENSDART00000144086
si:ch211-222n4.6
si:ch211-222n4.6
chr4_+_11464255 0.31 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr8_+_2438638 0.29 ENSDART00000141263
ENKD1
si:ch211-220d9.3
chr10_+_36184751 0.28 ENSDART00000162639
or108-2
odorant receptor, family D, subfamily 108, member 2
chr3_-_8399774 0.27 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
rbfox3b
RNA binding fox-1 homolog 3b
chr3_+_54047342 0.27 ENSDART00000178486
olfm2a
olfactomedin 2a
chr8_+_52503340 0.26 ENSDART00000168838
si:ch1073-392o20.1
si:ch1073-392o20.1
chr23_-_18130264 0.26 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr18_+_11970987 0.24 ENSDART00000144111
si:dkeyp-2c8.3
si:dkeyp-2c8.3
chr2_-_1443692 0.23 ENSDART00000004533
rpe65a
retinal pigment epithelium-specific protein 65a
chr18_+_11506561 0.21 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr23_+_40460333 0.21 ENSDART00000184658
soga3b
SOGA family member 3b
chr22_-_38934989 0.19 ENSDART00000008365
ncbp2
nuclear cap binding protein subunit 2
chr3_+_33341640 0.17 ENSDART00000186352
pyya
peptide YYa
chr17_-_28198099 0.17 ENSDART00000156143
htr1d
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr15_-_22074315 0.16 ENSDART00000149830
drd2a
dopamine receptor D2a
chr5_-_68782641 0.16 ENSDART00000141699
mepce
methylphosphate capping enzyme
chr2_+_29795833 0.15 ENSDART00000056750
si:ch211-207d6.2
si:ch211-207d6.2
chr4_+_13586689 0.11 ENSDART00000067161
ENSDART00000138201
tnpo3
transportin 3
chr3_+_32832538 0.10 ENSDART00000139410
cd2bp2
CD2 (cytoplasmic tail) binding protein 2
chr11_+_42726712 0.09 ENSDART00000028955
tdrd3
tudor domain containing 3
chr6_-_6487876 0.09 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr19_+_40856534 0.08 ENSDART00000051950
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr4_+_11384891 0.06 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr25_-_37262220 0.04 ENSDART00000153789
ENSDART00000155182
rfwd3
ring finger and WD repeat domain 3
chr8_-_52562672 0.04 ENSDART00000159333
ENSDART00000159974
si:ch73-199g24.2
si:ch73-199g24.2
chr11_+_28476298 0.04 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr23_+_31912882 0.04 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr5_+_64732036 0.03 ENSDART00000073950
olfm1a
olfactomedin 1a
chr9_+_350680 0.02 ENSDART00000172517
bpifcl
BPI fold containing family C, like

Network of associatons between targets according to the STRING database.

First level regulatory network of eve1+evx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.2 3.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.9 2.7 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.8 2.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 2.3 GO:0042755 eating behavior(GO:0042755)
0.5 3.0 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.5 1.4 GO:0019323 pentose catabolic process(GO:0019323)
0.4 1.2 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.4 3.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.4 1.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.3 5.9 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 1.0 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.3 4.3 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.3 1.3 GO:0002159 desmosome assembly(GO:0002159)
0.2 3.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 2.2 GO:0050957 equilibrioception(GO:0050957)
0.2 1.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 7.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 2.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 4.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 1.9 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.5 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 10.1 GO:0006096 glycolytic process(GO:0006096)
0.1 2.0 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 1.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.7 GO:0097065 anterior head development(GO:0097065)
0.1 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 7.2 GO:0017148 negative regulation of translation(GO:0017148)
0.1 0.6 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 0.7 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.2 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.5 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.4 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0042044 fluid transport(GO:0042044)
0.1 0.7 GO:0009303 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.2 GO:0016116 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.2 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 2.4 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.3 GO:0060465 pharynx development(GO:0060465)
0.0 1.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 2.4 GO:0007602 phototransduction(GO:0007602)
0.0 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.2 GO:0001757 somite specification(GO:0001757)
0.0 1.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.0 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 2.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.4 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.7 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 7.4 GO:0019752 carboxylic acid metabolic process(GO:0019752)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 3.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.9 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.3 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0030904 retromer complex(GO:0030904)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.2 GO:0043186 P granule(GO:0043186)
0.0 4.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.4 GO:0005930 axoneme(GO:0005930)
0.0 0.2 GO:0034518 RNA cap binding complex(GO:0034518)
0.0 8.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.7 GO:0004743 pyruvate kinase activity(GO:0004743)
1.1 4.3 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.1 7.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.0 5.1 GO:0009374 biotin binding(GO:0009374)
1.0 3.0 GO:0004061 arylformamidase activity(GO:0004061)
0.9 2.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.8 2.4 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.8 2.4 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.7 3.0 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.5 2.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.4 1.2 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.4 1.9 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 5.9 GO:0032190 acrosin binding(GO:0032190)
0.3 1.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 3.7 GO:2001069 glycogen binding(GO:2001069)
0.2 1.7 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.0 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.2 1.8 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 1.0 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 7.3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 5.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.2 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691) single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0051020 GTPase binding(GO:0051020)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 8.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 4.8 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 3.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 4.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 3.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 3.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation