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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for foxd2_foxd5
Z-value: 1.94
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Transcription factors associated with foxd2_foxd5
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
foxd2
|
ENSDARG00000058133 | forkhead box D2 |
|
foxd5
|
ENSDARG00000042485 | forkhead box D5 |
|
foxd5
|
ENSDARG00000109712 | forkhead box D5 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| foxd2 | dr11_v1_chr8_+_19674369_19674369 | -0.48 | 1.2e-06 | Click! |
| foxd5 | dr11_v1_chr8_+_30452945_30452945 | -0.20 | 5.3e-02 | Click! |
Activity profile of foxd2_foxd5 motif
Sorted Z-values of foxd2_foxd5 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_34127005 | 58.92 |
ENSDART00000167384
ENSDART00000078065 |
f5
|
coagulation factor V |
| chr14_+_21107032 | 58.78 |
ENSDART00000138319
ENSDART00000139103 ENSDART00000184735 |
aldob
|
aldolase b, fructose-bisphosphate |
| chr4_-_25215968 | 55.84 |
ENSDART00000066932
ENSDART00000066933 |
itih2
|
inter-alpha-trypsin inhibitor heavy chain 2 |
| chr12_-_22524388 | 45.21 |
ENSDART00000020942
|
shbg
|
sex hormone-binding globulin |
| chr14_+_11458044 | 40.97 |
ENSDART00000186425
|
si:ch211-153b23.5
|
si:ch211-153b23.5 |
| chr14_+_11457500 | 40.68 |
ENSDART00000169202
|
si:ch211-153b23.5
|
si:ch211-153b23.5 |
| chr21_+_40092301 | 39.40 |
ENSDART00000145150
|
serpinf2a
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a |
| chr18_-_46354269 | 35.14 |
ENSDART00000010813
|
foxa3
|
forkhead box A3 |
| chr21_+_27416284 | 33.31 |
ENSDART00000077593
ENSDART00000108763 |
cfb
|
complement factor B |
| chr22_-_23668356 | 31.71 |
ENSDART00000167106
ENSDART00000159622 ENSDART00000163228 |
cfh
|
complement factor H |
| chr3_-_15081874 | 30.97 |
ENSDART00000192532
|
nme4
|
NME/NM23 nucleoside diphosphate kinase 4 |
| chr22_-_17595310 | 29.68 |
ENSDART00000099056
|
gpx4a
|
glutathione peroxidase 4a |
| chr5_+_26795465 | 27.56 |
ENSDART00000053001
|
tcn2
|
transcobalamin II |
| chr6_-_55864687 | 25.92 |
ENSDART00000160991
|
cyp24a1
|
cytochrome P450, family 24, subfamily A, polypeptide 1 |
| chr9_-_16109001 | 25.33 |
ENSDART00000053473
|
upp2
|
uridine phosphorylase 2 |
| chr16_+_23975930 | 25.30 |
ENSDART00000147858
ENSDART00000144347 ENSDART00000115270 |
apoc4
|
apolipoprotein C-IV |
| chr13_-_4707018 | 25.23 |
ENSDART00000128422
|
oit3
|
oncoprotein induced transcript 3 |
| chr3_-_45848043 | 24.00 |
ENSDART00000055132
|
igfals
|
insulin-like growth factor binding protein, acid labile subunit |
| chr3_-_45848257 | 23.59 |
ENSDART00000147198
|
igfals
|
insulin-like growth factor binding protein, acid labile subunit |
| chr18_-_6803424 | 21.51 |
ENSDART00000142647
|
si:dkey-266m15.5
|
si:dkey-266m15.5 |
| chr16_+_23976227 | 21.14 |
ENSDART00000193013
|
apoc4
|
apolipoprotein C-IV |
| chr3_-_50139860 | 19.52 |
ENSDART00000101563
|
btr02
|
bloodthirsty-related gene family, member 2 |
| chr2_-_37956768 | 18.62 |
ENSDART00000034595
|
cbln10
|
cerebellin 10 |
| chr22_-_38819603 | 18.54 |
ENSDART00000104437
|
si:ch211-262h13.5
|
si:ch211-262h13.5 |
| chr15_+_45563656 | 18.54 |
ENSDART00000157501
|
cldn15lb
|
claudin 15-like b |
| chr19_+_9277327 | 17.96 |
ENSDART00000104623
ENSDART00000151164 |
si:rp71-15k1.1
|
si:rp71-15k1.1 |
| chr3_+_36424055 | 16.99 |
ENSDART00000170318
|
si:ch1073-443f11.2
|
si:ch1073-443f11.2 |
| chr2_-_127945 | 16.25 |
ENSDART00000056453
|
igfbp1b
|
insulin-like growth factor binding protein 1b |
| chr15_+_45563491 | 16.25 |
ENSDART00000191169
|
cldn15lb
|
claudin 15-like b |
| chr15_-_34408777 | 14.57 |
ENSDART00000139934
|
agmo
|
alkylglycerol monooxygenase |
| chr2_-_37960688 | 14.14 |
ENSDART00000055565
|
cbln14
|
cerebellin 14 |
| chr7_+_21841037 | 13.53 |
ENSDART00000077503
|
tm4sf5
|
transmembrane 4 L six family member 5 |
| chr7_+_27603211 | 13.05 |
ENSDART00000148782
|
cyp2r1
|
cytochrome P450, family 2, subfamily R, polypeptide 1 |
| chr20_-_30369598 | 12.78 |
ENSDART00000144549
|
allc
|
allantoicase |
| chr12_+_46543572 | 12.26 |
ENSDART00000167510
|
hid1b
|
HID1 domain containing b |
| chr17_-_10838434 | 11.98 |
ENSDART00000064597
|
lgals3b
|
lectin, galactoside binding soluble 3b |
| chr1_-_30473422 | 11.74 |
ENSDART00000164202
|
igf2bp2b
|
insulin-like growth factor 2 mRNA binding protein 2b |
| chr10_+_26972755 | 11.33 |
ENSDART00000042162
|
tm7sf2
|
transmembrane 7 superfamily member 2 |
| chr10_+_26973063 | 10.98 |
ENSDART00000143162
ENSDART00000186210 |
tm7sf2
|
transmembrane 7 superfamily member 2 |
| chr20_-_49889111 | 10.68 |
ENSDART00000058858
|
kif13bb
|
kinesin family member 13Bb |
| chr17_+_21964472 | 10.64 |
ENSDART00000063704
ENSDART00000188904 |
crip3
|
cysteine-rich protein 3 |
| chr11_-_18819178 | 9.11 |
ENSDART00000080355
|
zgc:175264
|
zgc:175264 |
| chr12_-_3237561 | 9.02 |
ENSDART00000164665
|
si:ch1073-13h15.3
|
si:ch1073-13h15.3 |
| chr3_-_16289826 | 8.96 |
ENSDART00000131972
|
bckdhbl
|
branched chain keto acid dehydrogenase E1, beta polypeptide, like |
| chr14_-_4121052 | 8.82 |
ENSDART00000167074
|
irf2
|
interferon regulatory factor 2 |
| chr11_-_42752884 | 8.70 |
ENSDART00000186025
|
si:ch73-106k19.5
|
si:ch73-106k19.5 |
| chr8_-_13013123 | 8.70 |
ENSDART00000147802
|
dennd2da
|
DENN/MADD domain containing 2Da |
| chr16_-_13388821 | 7.75 |
ENSDART00000144062
|
grin2db
|
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b |
| chr14_-_4120636 | 7.66 |
ENSDART00000059230
|
irf2
|
interferon regulatory factor 2 |
| chr19_-_22387141 | 7.40 |
ENSDART00000151234
|
eppk1
|
epiplakin 1 |
| chr11_-_18818640 | 7.38 |
ENSDART00000191610
ENSDART00000190055 |
zgc:175264
|
zgc:175264 |
| chr4_-_12723585 | 7.21 |
ENSDART00000185639
|
mgst1.2
|
microsomal glutathione S-transferase 1.2 |
| chr16_-_38629208 | 6.72 |
ENSDART00000126705
|
eif3ea
|
eukaryotic translation initiation factor 3, subunit E, a |
| chr25_+_17423515 | 6.71 |
ENSDART00000061738
|
elmo3
|
engulfment and cell motility 3 |
| chr9_-_33063083 | 6.59 |
ENSDART00000048550
|
si:ch211-125e6.5
|
si:ch211-125e6.5 |
| chr2_-_6112862 | 6.48 |
ENSDART00000164269
|
prdx1
|
peroxiredoxin 1 |
| chr20_+_26881600 | 6.44 |
ENSDART00000174799
|
serpinb1
|
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| chr8_-_15150131 | 6.23 |
ENSDART00000138253
|
bcar3
|
BCAR3, NSP family adaptor protein |
| chr7_+_56703254 | 6.17 |
ENSDART00000184547
ENSDART00000004964 ENSDART00000147259 ENSDART00000134173 |
nqo1
|
NAD(P)H dehydrogenase, quinone 1 |
| chr12_+_2648043 | 5.71 |
ENSDART00000082220
|
gdf2
|
growth differentiation factor 2 |
| chr18_-_24988645 | 5.55 |
ENSDART00000136434
ENSDART00000085735 |
chd2
|
chromodomain helicase DNA binding protein 2 |
| chr9_+_3170101 | 5.11 |
ENSDART00000164878
ENSDART00000160567 ENSDART00000161216 |
dync1i2a
|
dynein, cytoplasmic 1, intermediate chain 2a |
| chr20_-_6532462 | 5.00 |
ENSDART00000054653
|
mcm3l
|
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like |
| chr6_-_43616936 | 5.00 |
ENSDART00000149301
|
foxp1b
|
forkhead box P1b |
| chr22_-_9728208 | 4.86 |
ENSDART00000185962
|
si:dkey-286j17.4
|
si:dkey-286j17.4 |
| chr20_-_13623882 | 4.64 |
ENSDART00000125218
ENSDART00000152499 |
sytl3
|
synaptotagmin-like 3 |
| chr2_+_23007675 | 4.64 |
ENSDART00000163649
|
mknk2a
|
MAP kinase interacting serine/threonine kinase 2a |
| chr8_+_28695914 | 4.62 |
ENSDART00000033386
|
ocstamp
|
osteoclast stimulatory transmembrane protein |
| chr12_+_23424108 | 4.60 |
ENSDART00000077732
|
bambia
|
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a |
| chr7_+_21180747 | 4.57 |
ENSDART00000185543
|
serpinh2
|
serine (or cysteine) peptidase inhibitor, clade H, member 2 |
| chr22_+_11756040 | 4.38 |
ENSDART00000105808
|
krt97
|
keratin 97 |
| chr12_-_18961289 | 4.29 |
ENSDART00000168405
|
ep300a
|
E1A binding protein p300 a |
| chr18_+_44532370 | 4.28 |
ENSDART00000086952
|
st14a
|
suppression of tumorigenicity 14 (colon carcinoma) a |
| chr4_+_57093908 | 4.23 |
ENSDART00000170198
|
si:ch211-238e22.5
|
si:ch211-238e22.5 |
| chr12_-_30583668 | 4.20 |
ENSDART00000153406
|
casp7
|
caspase 7, apoptosis-related cysteine peptidase |
| chr10_+_39248911 | 4.14 |
ENSDART00000170079
ENSDART00000167974 |
foxred1
|
FAD-dependent oxidoreductase domain containing 1 |
| chr11_+_14284866 | 4.07 |
ENSDART00000163729
|
si:ch211-262i1.3
|
si:ch211-262i1.3 |
| chr22_-_4439311 | 3.91 |
ENSDART00000169317
|
uhrf1
|
ubiquitin-like with PHD and ring finger domains 1 |
| chr18_-_41161828 | 3.89 |
ENSDART00000114993
|
CABZ01005876.1
|
|
| chr16_+_46492994 | 3.79 |
ENSDART00000134734
|
rpz5
|
rapunzel 5 |
| chr5_+_35398745 | 3.78 |
ENSDART00000098010
|
ptger4b
|
prostaglandin E receptor 4 (subtype EP4) b |
| chr7_-_12909352 | 3.62 |
ENSDART00000172901
|
sh3gl3a
|
SH3-domain GRB2-like 3a |
| chr7_-_35515931 | 3.60 |
ENSDART00000193324
|
irx6a
|
iroquois homeobox 6a |
| chr20_-_22778394 | 3.57 |
ENSDART00000152645
|
fip1l1a
|
FIP1 like 1a (S. cerevisiae) |
| chr6_+_40437987 | 3.56 |
ENSDART00000136487
|
ghrl
|
ghrelin/obestatin prepropeptide |
| chr15_+_6459847 | 3.35 |
ENSDART00000157250
ENSDART00000065824 |
bace2
|
beta-site APP-cleaving enzyme 2 |
| chr10_-_22491353 | 3.34 |
ENSDART00000180783
ENSDART00000159564 |
epob
|
erythropoietin b |
| chr2_-_43583896 | 3.31 |
ENSDART00000161711
|
itgb1b
|
integrin, beta 1b |
| chr19_+_32856907 | 3.24 |
ENSDART00000148232
|
rpl30
|
ribosomal protein L30 |
| chr5_-_14344647 | 3.05 |
ENSDART00000188456
|
tet3
|
tet methylcytosine dioxygenase 3 |
| chr2_-_4787566 | 3.02 |
ENSDART00000160663
ENSDART00000157808 |
tnk2b
|
tyrosine kinase, non-receptor, 2b |
| chr18_-_17077596 | 2.98 |
ENSDART00000111821
|
il17c
|
interleukin 17c |
| chr3_-_34724879 | 2.97 |
ENSDART00000177021
|
thraa
|
thyroid hormone receptor alpha a |
| chr12_-_20120702 | 2.95 |
ENSDART00000153387
ENSDART00000158412 ENSDART00000112768 |
ubald1a
|
UBA-like domain containing 1a |
| chr18_-_17077419 | 2.92 |
ENSDART00000148714
|
il17c
|
interleukin 17c |
| chr2_-_985417 | 2.90 |
ENSDART00000140540
|
si:ch211-241e1.3
|
si:ch211-241e1.3 |
| chr9_-_33081781 | 2.78 |
ENSDART00000165748
|
zgc:172053
|
zgc:172053 |
| chr8_+_19624589 | 2.74 |
ENSDART00000185698
|
slc35a3a
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a |
| chr6_+_54187643 | 2.73 |
ENSDART00000056830
|
pacsin1b
|
protein kinase C and casein kinase substrate in neurons 1b |
| chr7_+_22637515 | 2.73 |
ENSDART00000158698
|
si:dkey-112a7.5
|
si:dkey-112a7.5 |
| chr1_-_35924495 | 2.72 |
ENSDART00000184424
|
smad1
|
SMAD family member 1 |
| chr19_+_816208 | 2.72 |
ENSDART00000093304
|
nrm
|
nurim |
| chr6_-_39919982 | 2.72 |
ENSDART00000065091
ENSDART00000064903 |
sumf1
|
sulfatase modifying factor 1 |
| chr1_+_58332000 | 2.61 |
ENSDART00000145234
|
ggt1l2.1
|
gamma-glutamyltransferase 1 like 2.1 |
| chr6_-_35051671 | 2.59 |
ENSDART00000132788
|
uap1
|
UDP-N-acetylglucosamine pyrophosphorylase 1 |
| chr4_-_14470071 | 2.55 |
ENSDART00000143773
|
plxnb2a
|
plexin b2a |
| chr9_+_22364997 | 2.54 |
ENSDART00000188054
ENSDART00000046116 |
crygs3
|
crystallin, gamma S3 |
| chr17_+_10074360 | 2.53 |
ENSDART00000166649
|
srp54
|
signal recognition particle 54 |
| chr5_+_36650096 | 2.50 |
ENSDART00000111414
|
alkbh6
|
alkB homolog 6 |
| chr19_+_7043634 | 2.43 |
ENSDART00000133954
|
mhc1uka
|
major histocompatibility complex class I UKA |
| chr6_-_24053404 | 2.41 |
ENSDART00000168511
|
si:dkey-44g17.6
|
si:dkey-44g17.6 |
| chr22_+_24673168 | 2.40 |
ENSDART00000135257
|
si:rp71-23d18.8
|
si:rp71-23d18.8 |
| chr19_+_11984725 | 2.40 |
ENSDART00000185960
|
spag1a
|
sperm associated antigen 1a |
| chr17_+_26828027 | 2.37 |
ENSDART00000042060
|
jade1
|
jade family PHD finger 1 |
| chr5_+_26686639 | 2.36 |
ENSDART00000079064
|
tango2
|
transport and golgi organization 2 homolog (Drosophila) |
| chr18_+_49248389 | 2.32 |
ENSDART00000059285
ENSDART00000142004 ENSDART00000132751 |
yif1b
|
Yip1 interacting factor homolog B (S. cerevisiae) |
| chr23_+_28381260 | 2.31 |
ENSDART00000162722
|
zgc:153867
|
zgc:153867 |
| chr25_-_7759453 | 2.26 |
ENSDART00000142439
ENSDART00000021577 |
phf21ab
|
PHD finger protein 21Ab |
| chr8_+_23703464 | 2.22 |
ENSDART00000132584
|
ppardb
|
peroxisome proliferator-activated receptor delta b |
| chr5_-_67750907 | 2.18 |
ENSDART00000172097
|
b4galt4
|
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| chr20_-_3166168 | 2.18 |
ENSDART00000134137
|
si:ch73-212j7.3
|
si:ch73-212j7.3 |
| chr12_-_34887943 | 2.09 |
ENSDART00000027379
|
bicral
|
BRD4 interacting chromatin remodeling complex associated protein like |
| chr2_-_40191603 | 1.99 |
ENSDART00000180691
|
si:ch211-122l24.6
|
si:ch211-122l24.6 |
| chr15_-_15968883 | 1.99 |
ENSDART00000166583
ENSDART00000154042 |
synrg
|
synergin, gamma |
| chr5_-_29238889 | 1.99 |
ENSDART00000143098
|
si:dkey-61l1.4
|
si:dkey-61l1.4 |
| chr4_-_75505048 | 1.98 |
ENSDART00000163665
|
si:dkey-71l4.5
|
si:dkey-71l4.5 |
| chr19_-_3874986 | 1.98 |
ENSDART00000161830
|
thrap3b
|
thyroid hormone receptor associated protein 3b |
| chr6_-_35052145 | 1.96 |
ENSDART00000073970
ENSDART00000185790 |
uap1
|
UDP-N-acetylglucosamine pyrophosphorylase 1 |
| chr16_-_16619854 | 1.93 |
ENSDART00000150512
ENSDART00000191306 ENSDART00000181773 ENSDART00000183231 |
cyp21a2
|
cytochrome P450, family 21, subfamily A, polypeptide 2 |
| chr15_-_37829160 | 1.90 |
ENSDART00000099425
|
ctrl
|
chymotrypsin-like |
| chr21_-_9383974 | 1.86 |
ENSDART00000160932
|
sdad1
|
SDA1 domain containing 1 |
| chr21_-_9384374 | 1.85 |
ENSDART00000169275
|
sdad1
|
SDA1 domain containing 1 |
| chr3_-_41292569 | 1.84 |
ENSDART00000111856
|
sdk1a
|
sidekick cell adhesion molecule 1a |
| chr17_+_30448452 | 1.84 |
ENSDART00000153939
|
lpin1
|
lipin 1 |
| chr7_-_17600415 | 1.83 |
ENSDART00000080717
|
nitr6b
|
novel immune-type receptor 6b |
| chr3_-_12227359 | 1.79 |
ENSDART00000167356
|
tfap4
|
transcription factor AP-4 (activating enhancer binding protein 4) |
| chr5_+_54400971 | 1.76 |
ENSDART00000169695
|
bspry
|
B-box and SPRY domain containing |
| chr7_+_53156810 | 1.76 |
ENSDART00000189816
|
cdh29
|
cadherin 29 |
| chr9_-_12269847 | 1.70 |
ENSDART00000136558
ENSDART00000144734 ENSDART00000131766 ENSDART00000032344 |
nup35
|
nucleoporin 35 |
| chr1_-_10473630 | 1.59 |
ENSDART00000040116
|
tnrc5
|
trinucleotide repeat containing 5 |
| chr7_-_58776400 | 1.59 |
ENSDART00000167433
|
sox17
|
SRY (sex determining region Y)-box 17 |
| chr17_-_27266053 | 1.57 |
ENSDART00000110903
|
E2F2
|
si:ch211-160f23.5 |
| chr2_+_27855102 | 1.57 |
ENSDART00000150330
|
buc
|
bucky ball |
| chr6_-_40098641 | 1.56 |
ENSDART00000017402
|
ip6k2b
|
inositol hexakisphosphate kinase 2b |
| chr15_-_8191992 | 1.54 |
ENSDART00000155381
ENSDART00000190714 |
bach1a
|
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a |
| chr2_+_47906240 | 1.54 |
ENSDART00000122206
|
ftr23
|
finTRIM family, member 23 |
| chr16_+_52966812 | 1.53 |
ENSDART00000148435
ENSDART00000049099 ENSDART00000150117 |
trip13
|
thyroid hormone receptor interactor 13 |
| chr8_+_37749263 | 1.48 |
ENSDART00000108556
ENSDART00000147942 |
npm2a
|
nucleophosmin/nucleoplasmin, 2a |
| chr3_-_29506960 | 1.47 |
ENSDART00000141720
|
cyth4a
|
cytohesin 4a |
| chr9_-_23147026 | 1.45 |
ENSDART00000167266
|
lypd6b
|
LY6/PLAUR domain containing 6B |
| chr2_-_5135125 | 1.43 |
ENSDART00000164039
|
ptmab
|
prothymosin, alpha b |
| chr16_+_11724230 | 1.40 |
ENSDART00000060266
|
ceacam1
|
carcinoembryonic antigen-related cell adhesion molecule 1 |
| chr8_+_26410197 | 1.37 |
ENSDART00000145836
ENSDART00000053447 |
ifrd2
|
interferon-related developmental regulator 2 |
| chr17_+_8292892 | 1.37 |
ENSDART00000125728
|
si:ch211-236p5.3
|
si:ch211-236p5.3 |
| chr2_-_51221198 | 1.35 |
ENSDART00000166869
|
pigrl4.2
|
polymeric immunoglobulin receptor-like 4.2 |
| chr5_+_33070608 | 1.34 |
ENSDART00000135063
|
npffr2b
|
neuropeptide FF receptor 2b |
| chr23_-_4925641 | 1.32 |
ENSDART00000140861
ENSDART00000060718 |
taz
|
tafazzin |
| chr22_+_31059919 | 1.29 |
ENSDART00000077063
|
sec13
|
SEC13 homolog, nuclear pore and COPII coat complex component |
| chr15_+_28368823 | 1.27 |
ENSDART00000142298
|
slc43a2a
|
solute carrier family 43 (amino acid system L transporter), member 2a |
| chr19_-_1948236 | 1.27 |
ENSDART00000163344
|
znrf2a
|
zinc and ring finger 2a |
| chr2_-_9748039 | 1.26 |
ENSDART00000134870
|
si:ch1073-170o4.1
|
si:ch1073-170o4.1 |
| chr15_-_5309213 | 1.21 |
ENSDART00000174081
|
or120-1
|
odorant receptor, family E, subfamily 120, member 1 |
| chr9_-_21231297 | 1.21 |
ENSDART00000162578
|
pla1a
|
phospholipase A1 member A |
| chr14_-_41556720 | 1.20 |
ENSDART00000149244
|
itga6l
|
integrin, alpha 6, like |
| chr1_-_44581937 | 1.19 |
ENSDART00000009858
|
tmx2b
|
thioredoxin-related transmembrane protein 2b |
| chr9_-_37749973 | 1.16 |
ENSDART00000087663
|
sema5ba
|
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba |
| chr10_+_26597990 | 1.14 |
ENSDART00000079187
|
fhl1b
|
four and a half LIM domains 1b |
| chr6_-_8704702 | 1.13 |
ENSDART00000064149
|
nabp1b
|
nucleic acid binding protein 1b |
| chr7_+_33424044 | 1.10 |
ENSDART00000180260
|
glceb
|
glucuronic acid epimerase b |
| chr21_+_22558187 | 1.07 |
ENSDART00000167599
|
chek1
|
checkpoint kinase 1 |
| chr7_+_29513161 | 1.05 |
ENSDART00000191846
|
si:dkey-182o15.5
|
si:dkey-182o15.5 |
| chr24_+_13642126 | 1.04 |
ENSDART00000126769
|
trpa1b
|
transient receptor potential cation channel, subfamily A, member 1b |
| chr11_-_37880492 | 1.03 |
ENSDART00000102868
|
etnk2
|
ethanolamine kinase 2 |
| chr20_-_24165509 | 0.96 |
ENSDART00000124919
|
map3k7
|
mitogen-activated protein kinase kinase kinase 7 |
| chr16_-_19373310 | 0.95 |
ENSDART00000148294
|
dnah11
|
dynein, axonemal, heavy chain 11 |
| chr24_+_3478871 | 0.94 |
ENSDART00000111491
ENSDART00000134598 ENSDART00000142407 |
wdr37
|
WD repeat domain 37 |
| chr1_-_10620345 | 0.91 |
ENSDART00000131294
ENSDART00000140495 |
trpc5a
|
transient receptor potential cation channel, subfamily C, member 5a |
| chr6_+_30491129 | 0.91 |
ENSDART00000088142
|
wwc3
|
WWC family member 3 |
| chr18_-_37007294 | 0.87 |
ENSDART00000088309
|
map3k10
|
mitogen-activated protein kinase kinase kinase 10 |
| chr9_+_52398531 | 0.87 |
ENSDART00000126215
|
dap1b
|
death associated protein 1b |
| chr8_-_47329755 | 0.82 |
ENSDART00000060853
|
pex10
|
peroxisomal biogenesis factor 10 |
| chr6_+_2097690 | 0.82 |
ENSDART00000193770
|
tgm2b
|
transglutaminase 2b |
| chr13_+_25505580 | 0.81 |
ENSDART00000140634
|
inpp5f
|
inositol polyphosphate-5-phosphatase F |
| chr20_+_43083745 | 0.79 |
ENSDART00000139014
ENSDART00000153438 |
moxd1l
|
monooxygenase, DBH-like 1, like |
| chr5_-_51756210 | 0.70 |
ENSDART00000163464
|
lhfpl2b
|
LHFPL tetraspan subfamily member 2b |
| chr11_-_20987378 | 0.69 |
ENSDART00000110140
|
taf4a
|
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor |
| chr18_-_37007061 | 0.68 |
ENSDART00000136432
|
map3k10
|
mitogen-activated protein kinase kinase kinase 10 |
| chr1_-_21287724 | 0.67 |
ENSDART00000193900
|
npy1r
|
neuropeptide Y receptor Y1 |
| chr15_-_28677725 | 0.65 |
ENSDART00000060255
|
blmh
|
bleomycin hydrolase |
| chr8_-_44586981 | 0.64 |
ENSDART00000026831
ENSDART00000113945 |
rsph14
|
radial spoke head 14 homolog |
| chr11_+_6295370 | 0.58 |
ENSDART00000139882
|
ranbp3a
|
RAN binding protein 3a |
| chr10_-_8294965 | 0.56 |
ENSDART00000167380
|
plpp1a
|
phospholipid phosphatase 1a |
| chr21_-_32284532 | 0.55 |
ENSDART00000190676
|
clk4b
|
CDC-like kinase 4b |
| chr2_-_51507540 | 0.54 |
ENSDART00000166605
ENSDART00000161093 |
pigrl2.3
|
polymeric immunoglobulin receptor-like 2.3 |
| chr3_-_39208714 | 0.54 |
ENSDART00000125730
|
si:ch211-232p21.6
|
si:ch211-232p21.6 |
| chr8_-_24791060 | 0.54 |
ENSDART00000111617
|
rbm15
|
RNA binding motif protein 15 |
| chr11_-_13152215 | 0.53 |
ENSDART00000160989
ENSDART00000158239 |
elovl1b
|
ELOVL fatty acid elongase 1b |
| chr8_-_52594111 | 0.52 |
ENSDART00000167667
|
si:ch73-199g24.2
|
si:ch73-199g24.2 |
| chr4_-_6373735 | 0.52 |
ENSDART00000140100
|
MDFIC
|
si:ch73-156e19.1 |
| chr13_+_23897975 | 0.51 |
ENSDART00000002244
|
sf3b5
|
splicing factor 3b, subunit 5 |
Network of associatons between targets according to the STRING database.
First level regulatory network of foxd2_foxd5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.7 | 35.1 | GO:0048785 | hatching gland development(GO:0048785) |
| 9.2 | 27.6 | GO:0015889 | cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889) |
| 8.6 | 25.9 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 4.3 | 12.8 | GO:0000256 | allantoin catabolic process(GO:0000256) |
| 2.9 | 14.6 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 2.5 | 25.3 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206) |
| 2.4 | 12.0 | GO:0048245 | eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) |
| 2.3 | 46.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 2.2 | 13.1 | GO:0033280 | response to vitamin D(GO:0033280) vitamin D metabolic process(GO:0042359) vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305) |
| 2.0 | 47.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 1.9 | 31.0 | GO:0006228 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 1.5 | 16.3 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 1.3 | 34.8 | GO:0035622 | intrahepatic bile duct development(GO:0035622) |
| 1.1 | 10.7 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 1.1 | 7.4 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.8 | 63.5 | GO:0007599 | hemostasis(GO:0007599) |
| 0.8 | 69.0 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.8 | 3.8 | GO:0071380 | response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380) |
| 0.7 | 22.3 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.7 | 5.0 | GO:1902292 | cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975) |
| 0.6 | 6.5 | GO:0071451 | response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748) |
| 0.6 | 3.1 | GO:0032616 | interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656) |
| 0.5 | 3.3 | GO:0048823 | nucleate erythrocyte development(GO:0048823) |
| 0.4 | 3.9 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 0.4 | 1.3 | GO:0070278 | extracellular matrix constituent secretion(GO:0070278) |
| 0.4 | 7.8 | GO:0060079 | excitatory postsynaptic potential(GO:0060079) |
| 0.4 | 3.6 | GO:0098787 | mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.4 | 1.5 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.4 | 4.6 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.3 | 1.0 | GO:0050968 | chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968) |
| 0.3 | 33.3 | GO:0072376 | complement activation(GO:0006956) protein activation cascade(GO:0072376) |
| 0.3 | 2.6 | GO:0031179 | peptide modification(GO:0031179) |
| 0.3 | 3.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.3 | 3.0 | GO:0002154 | thyroid hormone mediated signaling pathway(GO:0002154) |
| 0.3 | 6.2 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
| 0.3 | 1.9 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.3 | 3.3 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.3 | 29.7 | GO:0006979 | response to oxidative stress(GO:0006979) |
| 0.3 | 2.4 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.3 | 0.8 | GO:0042420 | octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333) |
| 0.3 | 1.6 | GO:0060832 | oocyte animal/vegetal axis specification(GO:0060832) |
| 0.3 | 2.5 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.2 | 6.7 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.2 | 2.2 | GO:0010887 | negative regulation of cholesterol storage(GO:0010887) |
| 0.2 | 67.9 | GO:0006914 | autophagy(GO:0006914) |
| 0.2 | 4.1 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.2 | 3.3 | GO:0043114 | regulation of vascular permeability(GO:0043114) |
| 0.2 | 2.7 | GO:0090481 | pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.2 | 5.9 | GO:0071222 | cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222) |
| 0.2 | 4.2 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.2 | 1.2 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.2 | 2.9 | GO:1900006 | positive regulation of dendrite development(GO:1900006) |
| 0.2 | 1.3 | GO:2000479 | regulation of cAMP-dependent protein kinase activity(GO:2000479) |
| 0.1 | 1.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999) |
| 0.1 | 0.4 | GO:0003214 | cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218) |
| 0.1 | 1.3 | GO:0046471 | cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471) |
| 0.1 | 8.4 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.1 | 1.2 | GO:0050975 | sensory perception of touch(GO:0050975) |
| 0.1 | 1.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.3 | GO:0072020 | proximal straight tubule development(GO:0072020) |
| 0.1 | 0.6 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.1 | 1.1 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 2.4 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.1 | 6.7 | GO:0006909 | phagocytosis(GO:0006909) |
| 0.1 | 0.4 | GO:0097355 | protein localization to heterochromatin(GO:0097355) |
| 0.1 | 1.6 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
| 0.1 | 1.6 | GO:0007257 | activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507) |
| 0.1 | 6.5 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
| 0.1 | 5.1 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.1 | 1.6 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.1 | 37.8 | GO:0008283 | cell proliferation(GO:0008283) |
| 0.1 | 0.3 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 1.1 | GO:1990798 | pancreas regeneration(GO:1990798) |
| 0.1 | 1.8 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
| 0.1 | 0.6 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.3 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.0 | 0.8 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 1.3 | GO:0015807 | L-amino acid transport(GO:0015807) |
| 0.0 | 1.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.5 | GO:0035999 | tetrahydrofolate interconversion(GO:0035999) |
| 0.0 | 2.4 | GO:0009306 | protein secretion(GO:0009306) |
| 0.0 | 1.8 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 4.3 | GO:0001947 | heart looping(GO:0001947) |
| 0.0 | 0.2 | GO:0090497 | skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497) |
| 0.0 | 1.1 | GO:0010212 | response to ionizing radiation(GO:0010212) |
| 0.0 | 1.0 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 0.5 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 2.3 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 0.8 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 2.5 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 14.3 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.0 | 0.0 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.0 | 5.0 | GO:0046777 | protein autophosphorylation(GO:0046777) |
| 0.0 | 0.7 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 2.9 | GO:0030334 | regulation of cell migration(GO:0030334) |
| 0.0 | 1.8 | GO:0009617 | response to bacterium(GO:0009617) |
| 0.0 | 0.1 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 12.3 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 1.5 | 12.0 | GO:0001772 | immunological synapse(GO:0001772) |
| 1.3 | 6.7 | GO:0071540 | eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540) |
| 0.7 | 7.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.6 | 24.8 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.5 | 7.8 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.4 | 5.1 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.4 | 2.5 | GO:0048500 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.3 | 5.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.3 | 34.8 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.3 | 3.9 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.2 | 3.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.2 | 1.6 | GO:0032019 | mitochondrial cloud(GO:0032019) |
| 0.2 | 1.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 2.4 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.1 | 2.7 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.1 | 6.0 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 1.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 156.6 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 50.9 | GO:0005815 | microtubule organizing center(GO:0005815) |
| 0.1 | 2.0 | GO:0030130 | trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.1 | 8.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 1.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 64.6 | GO:0005576 | extracellular region(GO:0005576) |
| 0.1 | 2.3 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.3 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 0.8 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 3.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 2.1 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.1 | 2.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 3.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.0 | 0.9 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 2.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.3 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 0.7 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 3.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.5 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 1.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 2.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.8 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 1.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.3 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.0 | 0.1 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.7 | GO:0030286 | dynein complex(GO:0030286) |
| 0.0 | 16.7 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 1.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.5 | 25.9 | GO:0070643 | vitamin D 25-hydroxylase activity(GO:0070643) |
| 6.2 | 49.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 5.9 | 29.7 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 3.4 | 27.6 | GO:0031419 | cobalamin binding(GO:0031419) |
| 2.4 | 12.0 | GO:0019865 | IgE binding(GO:0019863) immunoglobulin binding(GO:0019865) |
| 1.6 | 14.6 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 1.5 | 16.3 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995) |
| 1.4 | 12.8 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 1.2 | 7.4 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 1.1 | 3.3 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 1.0 | 28.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.9 | 59.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.9 | 6.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.9 | 4.6 | GO:0003977 | UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977) |
| 0.9 | 104.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.9 | 22.3 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.7 | 3.3 | GO:0098639 | C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.7 | 43.4 | GO:0042562 | hormone binding(GO:0042562) |
| 0.5 | 2.5 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.5 | 9.0 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.4 | 3.1 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.4 | 5.1 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.4 | 15.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.4 | 7.8 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.4 | 3.8 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.3 | 25.3 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
| 0.3 | 2.6 | GO:0036374 | peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374) |
| 0.3 | 4.2 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.3 | 1.1 | GO:0047464 | heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464) |
| 0.3 | 2.7 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.3 | 0.8 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.3 | 1.3 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.2 | 1.4 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.2 | 6.2 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 0.2 | 34.8 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.2 | 7.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 13.1 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.2 | 5.0 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.2 | 1.6 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.2 | 4.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 3.4 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.2 | 1.2 | GO:0004984 | olfactory receptor activity(GO:0004984) odorant binding(GO:0005549) |
| 0.2 | 39.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 2.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 2.7 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.1 | 4.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 2.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 11.7 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.1 | 4.6 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 3.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 1.6 | GO:0000828 | inositol hexakisphosphate kinase activity(GO:0000828) |
| 0.1 | 1.9 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.1 | 0.3 | GO:0030623 | U5 snRNA binding(GO:0030623) |
| 0.1 | 2.2 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 56.4 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.1 | 2.2 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
| 0.1 | 6.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 8.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 0.5 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 0.1 | 1.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 5.0 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 1.2 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 1.1 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.0 | 1.2 | GO:0015036 | disulfide oxidoreductase activity(GO:0015036) |
| 0.0 | 0.8 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 2.5 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.7 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.0 | 1.0 | GO:0015278 | calcium-release channel activity(GO:0015278) |
| 0.0 | 0.7 | GO:0016251 | obsolete general RNA polymerase II transcription factor activity(GO:0016251) |
| 0.0 | 5.7 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 5.2 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 3.3 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) |
| 0.0 | 1.3 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 1.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.3 | GO:0032041 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.5 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 1.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 7.5 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 3.2 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 4.1 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 33.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 2.1 | 93.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 25.4 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.4 | 67.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.4 | 8.4 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.3 | 52.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 4.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 6.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.2 | 6.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 1.6 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 1.0 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 1.1 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 6.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 1.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 5.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.6 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 16.3 | 65.0 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 5.9 | 47.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 5.9 | 58.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 3.2 | 25.3 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 2.8 | 58.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 2.0 | 35.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 1.7 | 40.9 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 1.5 | 31.0 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.9 | 22.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.9 | 16.5 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.5 | 4.2 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 3.6 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.2 | 2.7 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.2 | 2.9 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.2 | 2.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 1.1 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 0.1 | 6.3 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 1.6 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.1 | 1.0 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 2.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 1.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 5.8 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 1.4 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 1.3 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.8 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |