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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxh1+foxq1a+foxq1b

Z-value: 1.34

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Transcription factors associated with foxh1+foxq1a+foxq1b

Gene Symbol Gene ID Gene Info
foxq1a
ENSDARG00000030896 forkhead box Q1a
foxq1b
ENSDARG00000055395 forkhead box Q1b
foxh1
ENSDARG00000055630 forkhead box H1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxh1dr11_v1_chr12_-_13729263_137292630.643.4e-12Click!
foxq1bdr11_v1_chr20_+_26683933_266839400.422.0e-05Click!
foxq1adr11_v1_chr2_-_722156_7221700.232.8e-02Click!

Activity profile of foxh1+foxq1a+foxq1b motif

Sorted Z-values of foxh1+foxq1a+foxq1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_37837245 41.27 ENSDART00000171617
epd
ependymin
chr17_+_15534815 19.29 ENSDART00000159426
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr4_+_8797197 12.37 ENSDART00000158671
sult4a1
sulfotransferase family 4A, member 1
chr9_+_31282161 11.97 ENSDART00000010774
zic2a
zic family member 2 (odd-paired homolog, Drosophila), a
chr16_-_28856112 11.65 ENSDART00000078543
syt11b
synaptotagmin XIb
chr3_+_29714775 10.68 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr14_+_33458294 9.24 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr6_-_9792004 9.17 ENSDART00000081129
cdk15
cyclin-dependent kinase 15
chr14_-_24410673 9.09 ENSDART00000125923
cxcl14
chemokine (C-X-C motif) ligand 14
chr1_+_35790082 8.21 ENSDART00000085051
hhip
hedgehog interacting protein
chr21_+_22630627 7.63 ENSDART00000193092
si:dkeyp-69c1.7
si:dkeyp-69c1.7
chr1_+_9290103 7.61 ENSDART00000055009
uncx4.1
Unc4.1 homeobox (C. elegans)
chr4_+_12111154 7.02 ENSDART00000036779
tmem178b
transmembrane protein 178B
chr21_-_32487061 6.90 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
si:dkeyp-72g9.4
chr5_+_1278092 6.83 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr8_+_39634114 6.83 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr7_-_26076970 6.69 ENSDART00000101120
zgc:92664
zgc:92664
chr11_-_8126223 6.57 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
ttll7
tubulin tyrosine ligase-like family, member 7
chr9_+_18716485 6.45 ENSDART00000135125
serp2
stress-associated endoplasmic reticulum protein family member 2
chr1_+_24076243 6.42 ENSDART00000014608
mab21l2
mab-21-like 2
chr14_+_28486213 6.24 ENSDART00000161852
stag2b
stromal antigen 2b
chr15_+_7992906 6.17 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr2_-_55298075 6.15 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr20_+_33294428 6.15 ENSDART00000024104
mycn
MYCN proto-oncogene, bHLH transcription factor
chr16_+_31853919 6.14 ENSDART00000133886
atn1
atrophin 1
chr2_-_44282796 5.98 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr22_-_29689981 5.91 ENSDART00000009223
pdcd4b
programmed cell death 4b
chr18_-_17001056 5.89 ENSDART00000112627
tph2
tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)
chr15_+_23550890 5.89 ENSDART00000009796
ENSDART00000152720
MARK4
si:dkey-31m14.7
chr14_-_40389699 5.80 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr2_-_36933472 5.78 ENSDART00000170405
BX470229.2

chr19_-_17526735 5.77 ENSDART00000189391
thrb
thyroid hormone receptor beta
chr2_+_31957554 5.66 ENSDART00000012413
ankhb
ANKH inorganic pyrophosphate transport regulator b
chr8_-_16592491 5.60 ENSDART00000101655
calr
calreticulin
chr22_-_29906764 5.42 ENSDART00000019786
smc3
structural maintenance of chromosomes 3
chr5_+_49744713 5.42 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr11_+_37612214 5.41 ENSDART00000172899
ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr11_+_24046179 5.40 ENSDART00000006703
maf1
MAF1 homolog, negative regulator of RNA polymerase III
chr14_-_21219659 5.30 ENSDART00000089867
ppp2r2cb
protein phosphatase 2, regulatory subunit B, gamma b
chr17_+_24590177 5.29 ENSDART00000092941
rlf
rearranged L-myc fusion
chr1_+_44711446 5.19 ENSDART00000193481
ENSDART00000003895
ssrp1b
structure specific recognition protein 1b
chr17_-_19022990 5.19 ENSDART00000154186
flrt2
fibronectin leucine rich transmembrane protein 2
chr5_-_28767573 5.12 ENSDART00000158299
ENSDART00000043466
traf2a
Tnf receptor-associated factor 2a
chr7_+_28724919 5.12 ENSDART00000011324
ccdc102a
coiled-coil domain containing 102A
chr5_+_19712011 5.10 ENSDART00000131924
fam222a
family with sequence similarity 222, member A
chr3_-_49138004 5.08 ENSDART00000167173
gipc1
GIPC PDZ domain containing family, member 1
chr3_+_34821327 5.08 ENSDART00000055262
cdk5r1a
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr19_+_26718074 5.07 ENSDART00000134455
zgc:100906
zgc:100906
chr25_-_7925269 5.04 ENSDART00000014274
glcea
glucuronic acid epimerase a
chr17_-_42213285 4.99 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr16_+_25116827 4.88 ENSDART00000163244
si:ch211-261d7.6
si:ch211-261d7.6
chr3_-_39696066 4.88 ENSDART00000015393
b9d1
B9 protein domain 1
chr10_+_42678520 4.83 ENSDART00000182496
rhobtb2b
Rho-related BTB domain containing 2b
chr3_-_42086577 4.76 ENSDART00000083111
ENSDART00000187312
ttyh3a
tweety family member 3a
chr17_+_28005763 4.74 ENSDART00000155838
luzp1
leucine zipper protein 1
chr1_+_53321878 4.71 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr2_-_44283554 4.60 ENSDART00000184684
mpz
myelin protein zero
chr17_-_44440832 4.59 ENSDART00000148786
exoc5
exocyst complex component 5
chr22_+_24559947 4.56 ENSDART00000169847
wdr47b
WD repeat domain 47b
chr18_+_7286788 4.51 ENSDART00000022998
ANO2 (1 of many)
si:ch73-86n2.1
chr14_+_34966598 4.49 ENSDART00000004550
rnf145a
ring finger protein 145a
chr4_-_12102025 4.49 ENSDART00000048391
ENSDART00000023894
braf
B-Raf proto-oncogene, serine/threonine kinase
chr9_+_20554896 4.46 ENSDART00000144248
man1a2
mannosidase, alpha, class 1A, member 2
chr8_-_44223473 4.40 ENSDART00000098525
stx2b
syntaxin 2b
chr25_+_7229046 4.31 ENSDART00000149965
ENSDART00000041820
lingo1a
leucine rich repeat and Ig domain containing 1a
chr1_-_53756851 4.27 ENSDART00000122445
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr2_+_24199073 4.22 ENSDART00000144110
map4l
microtubule associated protein 4 like
chr20_-_9963713 4.21 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr19_+_5143128 4.16 ENSDART00000138011
ENSDART00000108541
si:dkey-89b17.4
si:dkey-89b17.4
chr6_-_6423885 4.14 ENSDART00000092257
si:ch211-194e18.2
si:ch211-194e18.2
chr14_-_33177935 4.10 ENSDART00000180583
ENSDART00000078856
dlg3
discs, large homolog 3 (Drosophila)
chr8_-_44223899 4.05 ENSDART00000143020
stx2b
syntaxin 2b
chr3_-_39695856 4.05 ENSDART00000148247
b9d1
B9 protein domain 1
chr13_-_27675212 4.03 ENSDART00000141035
rims1a
regulating synaptic membrane exocytosis 1a
chr3_+_59864872 4.01 ENSDART00000102014
mcrip1
MAPK regulated corepressor interacting protein 1
chr1_+_46194333 3.97 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr21_+_17542473 3.86 ENSDART00000005750
ENSDART00000141326
stom
stomatin
chr14_-_32403554 3.83 ENSDART00000172873
ENSDART00000173408
ENSDART00000173114
ENSDART00000185594
ENSDART00000186762
ENSDART00000010982
fgf13a
fibroblast growth factor 13a
chr7_+_22801465 3.77 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr8_-_11324143 3.65 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr8_-_13210959 3.64 ENSDART00000142224
si:ch73-61d6.3
si:ch73-61d6.3
chr11_+_37612672 3.63 ENSDART00000157993
hp1bp3
heterochromatin protein 1, binding protein 3
chr2_+_8649293 3.47 ENSDART00000081442
ENSDART00000186024
fubp1
far upstream element (FUSE) binding protein 1
chr12_-_34887943 3.42 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr12_-_31422433 3.38 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vti1a
vesicle transport through interaction with t-SNAREs 1A
chr1_+_44710955 3.36 ENSDART00000131296
ENSDART00000142187
ssrp1b
structure specific recognition protein 1b
chr7_+_33279108 3.34 ENSDART00000084530
coro2ba
coronin, actin binding protein, 2Ba
chr25_+_388258 3.33 ENSDART00000166834
rfx7b
regulatory factor X7b
chr23_+_6795531 3.30 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr3_+_22442445 3.29 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr24_+_39586701 3.28 ENSDART00000136447
si:dkey-161j23.7
si:dkey-161j23.7
chr3_+_40289418 3.27 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr3_+_54047342 3.26 ENSDART00000178486
olfm2a
olfactomedin 2a
chr11_-_27057572 3.26 ENSDART00000043091
iqsec1b
IQ motif and Sec7 domain 1b
chr18_+_20034023 3.25 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr17_-_18888959 3.16 ENSDART00000080029
ak7b
adenylate kinase 7b
chr18_-_34156765 3.14 ENSDART00000059400
c18h3orf33
c18h3orf33 homolog (H. sapiens)
chr4_+_15011341 3.14 ENSDART00000124452
ube2h
ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
chr25_-_20024829 3.14 ENSDART00000140182
ENSDART00000174776
cnot4a
CCR4-NOT transcription complex, subunit 4a
chr24_+_32472155 3.10 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr24_+_7336807 3.09 ENSDART00000137010
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr4_+_75200467 3.01 ENSDART00000122593
CABZ01043955.1

chr9_-_30494727 3.01 ENSDART00000148729
si:dkey-229b18.3
si:dkey-229b18.3
chr7_+_30240791 3.00 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr16_-_42461263 2.92 ENSDART00000109259
smarcc1a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr17_+_25856671 2.92 ENSDART00000064817
wapla
WAPL cohesin release factor a
chr25_-_4717462 2.92 ENSDART00000012603
drd4a
dopamine receptor D4a
chr13_+_25286538 2.89 ENSDART00000180282
chuk
conserved helix-loop-helix ubiquitous kinase
chr16_+_46410520 2.89 ENSDART00000131072
rpz2
rapunzel 2
chr17_-_12764360 2.88 ENSDART00000003418
brms1la
breast cancer metastasis-suppressor 1-like a
chr6_-_19341184 2.88 ENSDART00000168236
ENSDART00000167674
mif4gda
MIF4G domain containing a
chr3_+_18062871 2.85 ENSDART00000112384
ankrd40
ankyrin repeat domain 40
chr7_-_53117131 2.83 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr3_-_35554809 2.82 ENSDART00000010944
dctn5
dynactin 5
chr24_+_11381400 2.80 ENSDART00000058703
ackr4b
atypical chemokine receptor 4b
chr10_+_20180163 2.76 ENSDART00000080016
ppp3ccb
protein phosphatase 3, catalytic subunit, gamma isozyme, b
chr11_+_7580079 2.75 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adgrl2a
adhesion G protein-coupled receptor L2a
chr6_+_33881372 2.74 ENSDART00000165710
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr7_+_29080684 2.73 ENSDART00000173709
ENSDART00000173576
acd
ACD, shelterin complex subunit and telomerase recruitment factor
chr24_+_26039464 2.72 ENSDART00000131017
tnk2a
tyrosine kinase, non-receptor, 2a
chr17_-_29902187 2.67 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr1_+_40237276 2.67 ENSDART00000037553
faah2a
fatty acid amide hydrolase 2a
chr10_+_43039947 2.66 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr6_+_40874206 2.63 ENSDART00000004295
zgc:112163
zgc:112163
chr15_+_29662401 2.63 ENSDART00000135540
nrip1a
nuclear receptor interacting protein 1a
chr4_-_17642168 2.62 ENSDART00000007030
klhl42
kelch-like family, member 42
chr23_-_27857051 2.61 ENSDART00000043462
ENSDART00000137861
acvrl1
activin A receptor like type 1
chr13_+_39182099 2.61 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr16_-_21692024 2.61 ENSDART00000123597
si:ch211-154o6.2
si:ch211-154o6.2
chr14_-_21218891 2.60 ENSDART00000158294
ppp2r2cb
protein phosphatase 2, regulatory subunit B, gamma b
chr5_-_13766651 2.59 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr15_+_21712328 2.57 ENSDART00000192553
NKAPD1
zgc:162339
chr1_-_45580787 2.57 ENSDART00000135089
atf7ip
activating transcription factor 7 interacting protein
chr8_-_7847921 2.49 ENSDART00000188094
zgc:113363
zgc:113363
chr1_+_19083501 2.46 ENSDART00000002886
ENSDART00000131948
exosc9
exosome component 9
chr9_+_34397516 2.44 ENSDART00000011304
ENSDART00000192973
med14
mediator complex subunit 14
chr14_-_38809561 2.43 ENSDART00000159159
sil1
SIL1 nucleotide exchange factor
chr20_-_16156419 2.41 ENSDART00000037420
ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr9_+_17306162 2.38 ENSDART00000075926
scel
sciellin
chr3_+_34234029 2.35 ENSDART00000044859
znf207a
zinc finger protein 207, a
chr2_+_6126086 2.35 ENSDART00000179962
fzr1b
fizzy/cell division cycle 20 related 1b
chr21_-_13225402 2.33 ENSDART00000080347
wdr34
WD repeat domain 34
chr16_+_9580699 2.32 ENSDART00000165565
taf2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr18_+_40354998 2.30 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr3_-_43356082 2.28 ENSDART00000171213
uncx
UNC homeobox
chr25_+_24291156 2.27 ENSDART00000083407
b4galnt4a
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr8_+_4803906 2.26 ENSDART00000045533
tmem127
transmembrane protein 127
chr22_+_39054012 2.23 ENSDART00000191326
ip6k1
inositol hexakisphosphate kinase 1
chr12_-_28537615 2.22 ENSDART00000067762
MYO1D
si:ch211-94l19.4
chr9_+_34397843 2.20 ENSDART00000146314
med14
mediator complex subunit 14
chr12_+_22823219 2.16 ENSDART00000153199
ENSDART00000192571
afap1
actin filament associated protein 1
chr6_+_11250316 2.14 ENSDART00000137122
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr14_-_30960470 2.14 ENSDART00000129989
si:ch211-191o15.6
si:ch211-191o15.6
chr17_-_11417551 2.10 ENSDART00000128291
arid4a
AT rich interactive domain 4A (RBP1-like)
chr2_-_6482240 2.07 ENSDART00000132623
rgs13
regulator of G protein signaling 13
chr12_-_5455936 2.05 ENSDART00000109305
tbc1d12b
TBC1 domain family, member 12b
chr7_+_24153070 2.04 ENSDART00000076735
lrp10
low density lipoprotein receptor-related protein 10
chr21_-_2707768 2.03 ENSDART00000165384
CABZ01101739.1

chr12_+_18906939 2.03 ENSDART00000186074
josd1
Josephin domain containing 1
chr6_+_54680730 1.97 ENSDART00000074602
smpd2b
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr5_+_6755466 1.94 ENSDART00000163247
ENSDART00000114293
areg
amphiregulin
chr22_-_15437242 1.90 ENSDART00000063719
rpp21
ribonuclease P 21 subunit
chr10_-_20669635 1.89 ENSDART00000131361
kcnip3b
Kv channel interacting protein 3b, calsenilin
chr17_+_34244345 1.84 ENSDART00000006058
eif2s1a
eukaryotic translation initiation factor 2, subunit 1 alpha a
chr18_-_45761868 1.80 ENSDART00000025423
cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr23_-_41762956 1.79 ENSDART00000128302
stk35
serine/threonine kinase 35
chr15_+_42285643 1.77 ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr6_+_11250033 1.75 ENSDART00000065411
ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr3_+_50172452 1.73 ENSDART00000191224
epn3a
epsin 3a
chr23_+_2191773 1.71 ENSDART00000190876
ENSDART00000126768
cc2d2a
coiled-coil and C2 domain containing 2A
chr18_+_6039141 1.71 ENSDART00000138972
si:ch73-386h18.1
si:ch73-386h18.1
chr1_+_14658801 1.70 ENSDART00000192194
CR847936.1

chr18_+_40355408 1.70 ENSDART00000167134
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr16_-_9675982 1.68 ENSDART00000113724
mal2
mal, T cell differentiation protein 2 (gene/pseudogene)
chr12_+_32729470 1.63 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr13_-_23956178 1.63 ENSDART00000133646
phactr2
phosphatase and actin regulator 2
chr21_+_26733529 1.61 ENSDART00000168379
pcxa
pyruvate carboxylase a
chr11_+_24348425 1.59 ENSDART00000089747
nfs1
NFS1 cysteine desulfurase
chr10_-_27009413 1.57 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
uqcc3
ubiquinol-cytochrome c reductase complex assembly factor 3
chr11_+_22134540 1.53 ENSDART00000190502
MDFI
si:dkey-91m3.1
chr7_-_54679595 1.49 ENSDART00000165320
ccnd1
cyclin D1
chr9_+_7030016 1.48 ENSDART00000148047
ENSDART00000148181
inpp4aa
inositol polyphosphate-4-phosphatase type I Aa
chr3_+_23488652 1.47 ENSDART00000126282
nr1d1
nuclear receptor subfamily 1, group d, member 1
chr1_-_23370395 1.45 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
pds5a
PDS5 cohesin associated factor A
chr12_+_18906407 1.41 ENSDART00000105854
josd1
Josephin domain containing 1
chr4_-_1908179 1.40 ENSDART00000139586
ano6
anoctamin 6
chr13_-_31377299 1.39 ENSDART00000026692
ubtd1a
ubiquitin domain containing 1a
chr12_-_26609347 1.39 ENSDART00000035925
kctd2
potassium channel tetramerization domain containing 2
chr18_+_13077800 1.37 ENSDART00000161153
GAN
gigaxonin
chr14_-_15990361 1.33 ENSDART00000168075
trim105
tripartite motif containing 105
chr17_+_44441042 1.32 ENSDART00000142123
ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr18_-_29925717 1.32 ENSDART00000099281
mhc2dbb
major histocompatibility complex class II DBB gene
chr7_+_24494299 1.30 ENSDART00000087568
nelfa
negative elongation factor complex member A
chr13_-_23956361 1.29 ENSDART00000101150
phactr2
phosphatase and actin regulator 2
chr19_+_20177887 1.29 ENSDART00000008595
tra2a
transformer 2 alpha homolog
chr12_+_19408373 1.27 ENSDART00000114248
snx29
sorting nexin 29
chr15_-_19334448 1.26 ENSDART00000062576
thyn1
thymocyte nuclear protein 1
chr10_+_25355308 1.20 ENSDART00000100415
map3k7cl
map3k7 C-terminal like
chr15_+_32642878 1.18 ENSDART00000159932
trpc4b
transient receptor potential cation channel, subfamily C, member 4b
chr12_-_34716037 1.17 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxh1+foxq1a+foxq1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.0 12.0 GO:0021846 cell proliferation in forebrain(GO:0021846)
1.5 6.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
1.4 5.8 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
1.1 19.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
1.0 9.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.0 5.9 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
1.0 2.9 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.9 2.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.8 2.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.8 3.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.8 7.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.7 3.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.7 2.6 GO:0034405 response to fluid shear stress(GO:0034405)
0.6 6.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.6 10.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.6 5.4 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.6 2.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.6 1.7 GO:0045056 transcytosis(GO:0045056)
0.5 3.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.5 9.0 GO:0070828 heterochromatin organization(GO:0070828)
0.5 1.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 2.8 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.5 1.4 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.4 12.4 GO:0051923 sulfation(GO:0051923)
0.4 5.0 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.4 4.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.4 3.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 2.6 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4 6.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 3.3 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.4 3.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.4 6.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 14.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 41.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.3 1.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 8.5 GO:0007340 acrosome reaction(GO:0007340)
0.3 4.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 5.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.3 12.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.3 3.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 5.9 GO:0003171 atrioventricular valve development(GO:0003171)
0.3 6.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 1.6 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 5.1 GO:0048844 artery morphogenesis(GO:0048844)
0.2 5.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 7.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 6.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.2 0.7 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 3.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 1.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.6 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.2 0.8 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 5.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 4.6 GO:0019827 stem cell population maintenance(GO:0019827)
0.2 4.0 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.8 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 4.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 4.8 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 5.8 GO:0001841 neural tube formation(GO:0001841)
0.1 2.0 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 7.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 0.5 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.5 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.6 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.6 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.3 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 4.3 GO:0031103 axon regeneration(GO:0031103)
0.1 3.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 2.0 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.1 2.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 3.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 4.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 5.4 GO:1902275 regulation of chromatin organization(GO:1902275)
0.1 1.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.4 GO:0070254 mucus secretion(GO:0070254)
0.1 1.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 11.2 GO:0060326 cell chemotaxis(GO:0060326)
0.1 0.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.9 GO:0016575 histone deacetylation(GO:0016575)
0.1 11.1 GO:0006814 sodium ion transport(GO:0006814)
0.1 2.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 4.9 GO:0010506 regulation of autophagy(GO:0010506)
0.0 3.2 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 0.8 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.9 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 7.6 GO:0030334 regulation of cell migration(GO:0030334)
0.0 1.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 3.6 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 9.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 3.1 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 2.7 GO:0006497 protein lipidation(GO:0006497)
0.0 4.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 3.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.9 GO:0006821 chloride transport(GO:0006821)
0.0 1.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 6.2 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.7 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.1 GO:0008544 epidermis development(GO:0008544)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.7 GO:0016589 NURF complex(GO:0016589)
1.0 5.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.9 9.2 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.8 8.5 GO:0035101 FACT complex(GO:0035101)
0.7 4.6 GO:0070847 core mediator complex(GO:0070847)
0.6 10.6 GO:0043209 myelin sheath(GO:0043209)
0.6 8.9 GO:0036038 MKS complex(GO:0036038)
0.5 2.6 GO:0070724 BMP receptor complex(GO:0070724)
0.5 2.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 11.7 GO:0008278 cohesin complex(GO:0008278)
0.5 2.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 1.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.5 2.8 GO:0005955 calcineurin complex(GO:0005955)
0.4 6.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.4 8.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 4.2 GO:0005922 connexon complex(GO:0005922)
0.3 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 6.1 GO:0070822 Sin3-type complex(GO:0070822)
0.2 7.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 10.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 6.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 2.5 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 2.9 GO:0071564 npBAF complex(GO:0071564)
0.2 2.7 GO:0070187 telosome(GO:0070187)
0.2 1.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 4.6 GO:0000145 exocyst(GO:0000145)
0.2 3.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 1.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 3.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 3.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 10.1 GO:0032432 actin filament bundle(GO:0032432)
0.1 2.8 GO:0030057 desmosome(GO:0030057)
0.1 1.3 GO:0032021 NELF complex(GO:0032021)
0.1 4.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 3.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.0 GO:0071914 prominosome(GO:0071914)
0.1 2.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 3.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 30.7 GO:0005764 lysosome(GO:0005764)
0.1 3.4 GO:0031902 late endosome membrane(GO:0031902)
0.1 5.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.1 3.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 9.0 GO:0000786 nucleosome(GO:0000786)
0.1 4.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 3.8 GO:0030426 growth cone(GO:0030426)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 4.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 11.6 GO:0070382 exocytic vesicle(GO:0070382)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 5.6 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.0 GO:0055037 recycling endosome(GO:0055037)
0.0 2.4 GO:0000776 kinetochore(GO:0000776)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.9 GO:0000785 chromatin(GO:0000785)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 15.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 2.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)
0.0 6.6 GO:0043005 neuron projection(GO:0043005)
0.0 13.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0043621 protein self-association(GO:0043621)
1.5 8.9 GO:0008158 hedgehog receptor activity(GO:0008158)
1.4 5.8 GO:0070324 thyroid hormone binding(GO:0070324)
1.3 5.0 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
1.2 5.9 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
1.1 5.7 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.9 9.2 GO:0030332 cyclin binding(GO:0030332)
0.9 2.7 GO:0019777 Atg12 transferase activity(GO:0019777)
0.8 4.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.7 2.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.6 3.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.6 3.1 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.5 1.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.5 4.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 1.6 GO:1901612 cardiolipin binding(GO:1901612)
0.5 6.6 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.5 2.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 2.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.4 4.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 5.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.3 17.6 GO:0031491 nucleosome binding(GO:0031491)
0.3 2.9 GO:0008494 translation activator activity(GO:0008494)
0.3 6.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 11.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 0.7 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 2.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 2.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 2.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 3.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 12.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 1.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 14.5 GO:0016247 channel regulator activity(GO:0016247)
0.2 1.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 5.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 9.1 GO:0008009 chemokine activity(GO:0008009)
0.1 1.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 11.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 3.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 7.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 7.6 GO:0005178 integrin binding(GO:0005178)
0.1 4.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 2.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 19.3 GO:0005516 calmodulin binding(GO:0005516)
0.1 10.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 3.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 4.0 GO:0044325 ion channel binding(GO:0044325)
0.1 2.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 5.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 5.6 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 2.1 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 3.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 3.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 11.4 GO:0008017 microtubule binding(GO:0008017)
0.0 31.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 7.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.2 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.7 GO:0030276 clathrin binding(GO:0030276)
0.0 4.2 GO:0015293 symporter activity(GO:0015293)
0.0 1.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 4.1 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.5 GO:0003682 chromatin binding(GO:0003682)
0.0 5.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 1.6 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 5.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 7.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.6 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.2 PID ATM PATHWAY ATM pathway
0.0 1.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.9 2.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.6 5.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 4.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.4 4.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 2.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 4.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 9.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 2.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 4.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 5.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 4.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 4.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA