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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxj2

Z-value: 0.87

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Transcription factors associated with foxj2

Gene Symbol Gene ID Gene Info
foxj2
ENSDARG00000057680 forkhead box J2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxj2dr11_v1_chr16_-_12784373_127843730.671.3e-13Click!

Activity profile of foxj2 motif

Sorted Z-values of foxj2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_45177373 13.49 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr19_-_48340774 12.93 ENSDART00000168065
si:ch73-359m17.5
si:ch73-359m17.5
chr14_+_20911310 8.21 ENSDART00000160318
lygl2
lysozyme g-like 2
chr8_+_32406885 8.16 ENSDART00000167600
epgn
epithelial mitogen homolog (mouse)
chr15_+_42573909 8.10 ENSDART00000181801
CLDN8 (1 of many)
zgc:110333
chr4_+_26357221 8.07 ENSDART00000187684
ENSDART00000101545
ENSDART00000148296
ENSDART00000171433
tnni1d
troponin I, skeletal, slow d
chr5_-_63302944 8.00 ENSDART00000047110
gsnb
gelsolin b
chr5_-_24201437 7.93 ENSDART00000114113
sox19a
SRY (sex determining region Y)-box 19a
chr15_-_29598444 6.48 ENSDART00000154847
si:ch211-207n23.2
si:ch211-207n23.2
chr9_-_6380653 6.15 ENSDART00000078523
ecrg4a
esophageal cancer related gene 4a
chr18_-_44316920 6.05 ENSDART00000098599
si:ch211-151h10.2
si:ch211-151h10.2
chr4_-_16353733 5.95 ENSDART00000186785
lum
lumican
chr10_-_15672862 5.77 ENSDART00000109231
mamdc2b
MAM domain containing 2b
chr4_+_76671012 5.22 ENSDART00000005585
ms4a17a.2
membrane-spanning 4-domains, subfamily A, member 17a.2
chr11_+_37768298 5.12 ENSDART00000166886
sox13
SRY (sex determining region Y)-box 13
chr8_-_46457233 4.50 ENSDART00000113214
sult1st7
sulfotransferase family 1, cytosolic sulfotransferase 7
chr16_+_35916371 4.38 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr15_-_9002155 4.34 ENSDART00000126708
rhoub
ras homolog family member Ub
chr22_-_28653074 4.34 ENSDART00000154717
col8a1b
collagen, type VIII, alpha 1b
chr18_-_15911394 4.27 ENSDART00000091339
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr12_-_44018667 4.24 ENSDART00000170692
si:dkey-201i2.4
si:dkey-201i2.4
chr19_+_18739085 4.07 ENSDART00000188868
spaca4l
sperm acrosome associated 4 like
chr18_+_35742838 3.91 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr16_+_44768361 3.55 ENSDART00000036302
upk1a
uroplakin 1a
chr7_-_28413224 3.48 ENSDART00000076502
rerglb
RERG/RAS-like b
chr18_+_25225524 3.37 ENSDART00000055563
si:dkeyp-59c12.1
si:dkeyp-59c12.1
chr15_+_11883804 3.37 ENSDART00000163255
gpr184
G protein-coupled receptor 184
chr23_-_27822920 3.35 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr14_+_21699129 3.30 ENSDART00000073707
stx3a
syntaxin 3A
chr8_-_39838660 3.24 ENSDART00000139266
ftr98
finTRIM family, member 98
chr13_-_377256 3.18 ENSDART00000137398
ch1073-291c23.1
ch1073-291c23.1
chr2_-_36918709 3.09 ENSDART00000084876
zgc:153654
zgc:153654
chr3_+_32112004 3.04 ENSDART00000105272
zgc:173593
zgc:173593
chr1_+_17527931 3.00 ENSDART00000131927
casp3a
caspase 3, apoptosis-related cysteine peptidase a
chr21_+_45757317 2.93 ENSDART00000163152
h2afy
H2A histone family, member Y
chr16_+_33143503 2.92 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_46277593 2.81 ENSDART00000045598
zgc:110626
zgc:110626
chr25_-_35182347 2.79 ENSDART00000115210
ano9a
anoctamin 9a
chr19_+_19767567 2.78 ENSDART00000169074
hoxa3a
homeobox A3a
chr7_-_28549361 2.76 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
st5
suppression of tumorigenicity 5
chr23_-_17450746 2.64 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tpd52l2b
tumor protein D52-like 2b
chr20_+_34770197 2.54 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr6_-_14004772 2.54 ENSDART00000185629
zgc:92027
zgc:92027
chr14_-_5690363 2.52 ENSDART00000144539
tlx2
T cell leukemia homeobox 2
chr7_-_43840680 2.51 ENSDART00000002279
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_-_1948236 2.42 ENSDART00000163344
znrf2a
zinc and ring finger 2a
chr6_+_7466223 2.33 ENSDART00000148908
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr3_-_57762247 2.23 ENSDART00000156522
cant1a
calcium activated nucleotidase 1a
chr15_-_23761580 2.23 ENSDART00000137918
bbc3
BCL2 binding component 3
chr12_-_17479078 2.21 ENSDART00000079115
papss2b
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr19_+_6990970 2.18 ENSDART00000158758
ENSDART00000160482
ENSDART00000193566
kifc1
kinesin family member C1
chr4_-_12795436 2.14 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr15_-_4415917 2.12 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr1_-_49947290 2.09 ENSDART00000141476
sgms2
sphingomyelin synthase 2
chr14_+_21699414 2.07 ENSDART00000169942
stx3a
syntaxin 3A
chr25_+_29160102 2.02 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr14_-_34633960 2.00 ENSDART00000128869
ENSDART00000179977
afap1l1a
actin filament associated protein 1-like 1a
chr18_+_7553950 1.88 ENSDART00000193420
ENSDART00000062143
zgc:77650
zgc:77650
chr5_+_63302660 1.75 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr16_+_10422836 1.73 ENSDART00000161568
ino80e
INO80 complex subunit E
chr15_+_21254800 1.71 ENSDART00000142902
usf1
upstream transcription factor 1
chr24_+_38201089 1.69 ENSDART00000132338
igl3v2
immunoglobulin light 3 variable 2
chr8_+_10305400 1.69 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr18_+_17534627 1.67 ENSDART00000061007
mt2
metallothionein 2
chr20_-_33966148 1.65 ENSDART00000148111
selp
selectin P
chr4_+_8168514 1.64 ENSDART00000150830
ninj2
ninjurin 2
chr2_-_51507540 1.64 ENSDART00000166605
ENSDART00000161093
pigrl2.3
polymeric immunoglobulin receptor-like 2.3
chr9_-_34842414 1.62 ENSDART00000126348
BX601644.1
Danio rerio cytokine receptor-like factor 2 (crlf2), mRNA.
chr4_-_19884440 1.62 ENSDART00000182979
ENSDART00000105967
cacna2d1a
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr5_-_69212184 1.59 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr4_-_12795030 1.58 ENSDART00000150427
b2m
beta-2-microglobulin
chr19_+_20177887 1.57 ENSDART00000008595
tra2a
transformer 2 alpha homolog
chr25_-_13789955 1.54 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
ckap5
cytoskeleton associated protein 5
chr1_-_54938137 1.54 ENSDART00000147212
crtac1a
cartilage acidic protein 1a
chr16_+_10318893 1.53 ENSDART00000055380
tubb5
tubulin, beta 5
chr16_+_54210554 1.48 ENSDART00000172622
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr13_-_25476920 1.47 ENSDART00000131403
tial1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr17_-_53439866 1.46 ENSDART00000154826
mycbp
c-myc binding protein
chr17_+_51743908 1.35 ENSDART00000149039
ENSDART00000148869
odc1
ornithine decarboxylase 1
chr2_+_39618951 1.35 ENSDART00000077108
zgc:136870
zgc:136870
chr8_-_43750062 1.35 ENSDART00000142243
ulk1a
unc-51 like autophagy activating kinase 1a
chr7_-_17337233 1.33 ENSDART00000050236
ENSDART00000102141
nitr8
novel immune-type receptor 8
chr3_+_13862753 1.33 ENSDART00000168315
ilf3b
interleukin enhancer binding factor 3b
chr7_-_43840418 1.32 ENSDART00000174592
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr15_-_29162193 1.30 ENSDART00000138449
ENSDART00000099885
xaf1
XIAP associated factor 1
chr19_-_35492693 1.29 ENSDART00000135838
ENSDART00000051745
ENSDART00000177052
ptp4a2b
protein tyrosine phosphatase type IVA, member 2b
chr13_-_869808 1.29 ENSDART00000189029
AL929536.6

chr6_-_29288155 1.28 ENSDART00000078630
nme7
NME/NM23 family member 7
chr17_+_33415319 1.27 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr16_+_13818500 1.27 ENSDART00000135245
flcn
folliculin
chr4_-_19883985 1.26 ENSDART00000014440
cacna2d1a
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr15_-_28860282 1.25 ENSDART00000156738
gpr4
G protein-coupled receptor 4
chr5_+_42957503 1.24 ENSDART00000192885
mob1ba
MOB kinase activator 1Ba
chr9_+_8942258 1.20 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr10_-_11261565 1.18 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr13_-_15986871 1.18 ENSDART00000189394
ikzf1
IKAROS family zinc finger 1 (Ikaros)
chr17_+_5985933 1.17 ENSDART00000190844
zgc:194275
zgc:194275
chr17_+_15534815 1.15 ENSDART00000159426
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr22_+_4442473 1.14 ENSDART00000170751
ticam1
toll-like receptor adaptor molecule 1
chr15_-_36357889 1.13 ENSDART00000156377
si:dkey-23k10.5
si:dkey-23k10.5
chr11_-_11878099 1.12 ENSDART00000188314
wipf2a
WAS/WASL interacting protein family, member 2a
chr19_-_1920613 1.12 ENSDART00000186176
si:ch211-149a19.3
si:ch211-149a19.3
chr1_+_40566978 1.10 ENSDART00000137047
ENSDART00000135578
scoca
short coiled-coil protein a
chr18_+_41561285 1.09 ENSDART00000169621
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr17_+_33415542 1.09 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr3_-_55328548 1.08 ENSDART00000082944
dock6
dedicator of cytokinesis 6
chr13_+_30421472 1.07 ENSDART00000143569
zmiz1a
zinc finger, MIZ-type containing 1a
chr4_-_31700186 1.03 ENSDART00000183986
ENSDART00000180890
si:dkey-16p6.1
si:dkey-16p6.1
chr6_-_18393476 1.03 ENSDART00000168309
trim25
tripartite motif containing 25
chr8_-_10949847 1.02 ENSDART00000123209
pqlc2
PQ loop repeat containing 2
chr21_+_38732945 1.00 ENSDART00000076157
rab24
RAB24, member RAS oncogene family
chr3_+_32129632 0.99 ENSDART00000174522
zgc:109934
zgc:109934
chr25_-_37465064 0.97 ENSDART00000186128
zgc:158366
zgc:158366
chr18_+_41560822 0.97 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr2_+_22602301 0.96 ENSDART00000038514
sept2
septin 2
chr10_+_15025006 0.94 ENSDART00000145192
ENSDART00000140084
si:dkey-88l16.5
si:dkey-88l16.5
chr2_-_38337122 0.93 ENSDART00000076523
ENSDART00000187473
slc7a8b
solute carrier family 7 (amino acid transporter light chain, L system), member 8b
chr14_+_35279343 0.90 ENSDART00000187750
clint1a
clathrin interactor 1a
chr3_-_62194512 0.90 ENSDART00000074174
tbl3
transducin (beta)-like 3
chr12_+_5977777 0.87 ENSDART00000152302
si:ch211-131k2.2
si:ch211-131k2.2
chr16_-_41646164 0.86 ENSDART00000184257
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr3_+_34159192 0.85 ENSDART00000151119
carm1
coactivator-associated arginine methyltransferase 1
chr25_+_17920361 0.85 ENSDART00000185644
borcs5
BLOC-1 related complex subunit 5
chr6_+_11829867 0.85 ENSDART00000151044
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr4_-_75681004 0.84 ENSDART00000186296
si:dkey-71l4.5
si:dkey-71l4.5
chr25_-_3217115 0.84 ENSDART00000032390
gtf2h1
general transcription factor IIH, polypeptide 1
chr4_+_13586455 0.81 ENSDART00000187230
tnpo3
transportin 3
chr19_+_48018802 0.80 ENSDART00000161339
ENSDART00000166978
UBE2M
si:ch1073-205c8.3
chr12_-_8817999 0.80 ENSDART00000113148
jmjd1cb
jumonji domain containing 1Cb
chr6_+_12527725 0.80 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr7_-_20464468 0.79 ENSDART00000134700
cnpy4
canopy4
chr24_+_17345521 0.78 ENSDART00000024722
ENSDART00000154250
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr18_+_20034023 0.78 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr4_+_14727212 0.76 ENSDART00000158094
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr4_+_43700319 0.76 ENSDART00000141967
si:ch211-226o13.1
si:ch211-226o13.1
chr13_+_31687973 0.76 ENSDART00000076479
slc38a6
solute carrier family 38, member 6
chr23_-_41762956 0.73 ENSDART00000128302
stk35
serine/threonine kinase 35
chr12_-_33706726 0.72 ENSDART00000153135
myo15b
myosin XVB
chr4_+_14727018 0.71 ENSDART00000124189
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr19_-_6134802 0.70 ENSDART00000140051
cica
capicua transcriptional repressor a
chr17_+_38602790 0.70 ENSDART00000062010
ccdc88c
coiled-coil domain containing 88C
chr2_-_42492201 0.69 ENSDART00000180762
ENSDART00000009093
esyt2a
extended synaptotagmin-like protein 2a
chr19_+_4856351 0.67 ENSDART00000093402
cdk12
cyclin-dependent kinase 12
chr16_+_45922175 0.67 ENSDART00000018253
rbm8a
RNA binding motif protein 8A
chr10_+_42898103 0.66 ENSDART00000015872
zcchc9
zinc finger, CCHC domain containing 9
chr3_-_31893008 0.65 ENSDART00000127297
ddx42
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr23_+_20640875 0.63 ENSDART00000147382
uba1
ubiquitin-like modifier activating enzyme 1
chr16_-_5154024 0.63 ENSDART00000132069
ENSDART00000060635
dctn3
dynactin 3 (p22)
chr8_-_11202378 0.63 ENSDART00000147817
ENSDART00000174039
fam208b
family with sequence similarity 208, member B
chr23_-_10914275 0.63 ENSDART00000112965
pdzrn3a
PDZ domain containing RING finger 3a
chr22_-_718615 0.62 ENSDART00000149320
arl8a
ADP-ribosylation factor-like 8A
chr23_-_1571682 0.61 ENSDART00000013635
fbxo30b
F-box protein 30b
chr1_-_26444075 0.60 ENSDART00000125690
ints12
integrator complex subunit 12
chr22_+_2254972 0.60 ENSDART00000144906
znf1157
zinc finger protein 1157
chr23_+_40275601 0.59 ENSDART00000076876
fam46ab
family with sequence similarity 46, member Ab
chr17_-_28797395 0.58 ENSDART00000134735
scfd1
sec1 family domain containing 1
chr12_+_11352630 0.58 ENSDART00000129495
si:rp71-19m20.1
si:rp71-19m20.1
chr10_+_45031398 0.58 ENSDART00000160536
gnsb
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr17_-_39761086 0.56 ENSDART00000032410
gpr132a
G protein-coupled receptor 132a
chr1_-_9940494 0.56 ENSDART00000138726
tmem8a
transmembrane protein 8A
chr7_+_9904627 0.53 ENSDART00000172824
cers3a
ceramide synthase 3a
chr14_+_6991142 0.50 ENSDART00000157635
ENSDART00000059918
hnrnph1
heterogeneous nuclear ribonucleoprotein H1
chr4_+_13586689 0.50 ENSDART00000067161
ENSDART00000138201
tnpo3
transportin 3
chr1_+_9994811 0.49 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr23_+_45966436 0.48 ENSDART00000172160
CABZ01069338.1

chr17_-_681142 0.48 ENSDART00000165583
soul3
heme-binding protein soul3
chr10_-_42776344 0.47 ENSDART00000190653
ENSDART00000130229
wdr45
WD repeat domain 45
chr23_-_41762797 0.47 ENSDART00000186564
stk35
serine/threonine kinase 35
chr23_-_27607039 0.47 ENSDART00000183639
phf8
PHD finger protein 8
chr8_-_38477817 0.45 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr10_-_11261386 0.44 ENSDART00000189946
ptbp3
polypyrimidine tract binding protein 3
chr13_+_47007075 0.44 ENSDART00000109247
ENSDART00000183205
ENSDART00000180924
ENSDART00000133146
anapc1
anaphase promoting complex subunit 1
chr25_+_3217419 0.44 ENSDART00000104859
rccd1
RCC1 domain containing 1
chr23_+_40275400 0.43 ENSDART00000184259
fam46ab
family with sequence similarity 46, member Ab
chr10_+_36029537 0.43 ENSDART00000165386
hmgb1a
high mobility group box 1a
chr18_+_38885309 0.43 ENSDART00000041597
arpp19a
cAMP-regulated phosphoprotein 19a
chr3_+_28860283 0.42 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr8_-_1278937 0.41 ENSDART00000112130
ENSDART00000179683
aaed1
AhpC/TSA antioxidant enzyme domain containing 1
chr6_+_29288006 0.41 ENSDART00000043496
zgc:172121
zgc:172121
chr19_+_46222428 0.40 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr19_-_11846958 0.40 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr15_+_618081 0.37 ENSDART00000181518
si:ch211-210b2.1
si:ch211-210b2.1
chr15_-_5901514 0.36 ENSDART00000155252
si:ch73-281n10.2
si:ch73-281n10.2
chr14_-_25577094 0.36 ENSDART00000163669
cplx2
complexin 2
chr5_+_12590403 0.35 ENSDART00000133167
si:dkey-98f17.5
si:dkey-98f17.5
chr3_+_59864872 0.34 ENSDART00000102014
mcrip1
MAPK regulated corepressor interacting protein 1
chr25_+_17920668 0.34 ENSDART00000093358
borcs5
BLOC-1 related complex subunit 5
chr9_-_32158288 0.33 ENSDART00000037182
ankrd44
ankyrin repeat domain 44
chr16_-_20870143 0.32 ENSDART00000169541
ENSDART00000040727
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr11_-_45420212 0.32 ENSDART00000182042
ENSDART00000163185
ankrd13c
ankyrin repeat domain 13C
chr22_-_9728208 0.32 ENSDART00000185962
si:dkey-286j17.4
si:dkey-286j17.4
chr5_+_22970617 0.29 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr19_-_15229421 0.27 ENSDART00000055619
phactr4a
phosphatase and actin regulator 4a
chr3_+_14571813 0.26 ENSDART00000146728
ENSDART00000171731
znf653
zinc finger protein 653
chr12_-_9790485 0.26 ENSDART00000027321
prdm9
PR domain containing 9
chr18_+_3338228 0.25 ENSDART00000161520
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr2_-_29996036 0.24 ENSDART00000020792
cnpy1
canopy1
chr13_-_10431476 0.23 ENSDART00000133968
camkmt
calmodulin-lysine N-methyltransferase
chr3_-_37588855 0.22 ENSDART00000149258
arf2a
ADP-ribosylation factor 2a
chr15_-_617797 0.22 ENSDART00000154224
si:ch73-144d13.7
si:ch73-144d13.7

Network of associatons between targets according to the STRING database.

First level regulatory network of foxj2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
2.1 6.2 GO:0070314 G1 to G0 transition(GO:0070314)
1.1 5.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.0 3.0 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.9 8.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.7 2.2 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.5 4.3 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.4 2.2 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 2.8 GO:0060017 parathyroid gland development(GO:0060017)
0.4 1.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 1.1 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.4 2.5 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.4 1.8 GO:0010447 response to acidic pH(GO:0010447)
0.3 1.0 GO:0039531 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.3 3.3 GO:0001709 cell fate determination(GO:0001709)
0.3 0.9 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.3 1.5 GO:0000012 single strand break repair(GO:0000012)
0.3 1.7 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.3 3.7 GO:0045824 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.3 8.0 GO:0051014 actin filament severing(GO:0051014)
0.2 1.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 0.9 GO:0055071 manganese ion homeostasis(GO:0055071)
0.2 1.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 8.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.5 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 6.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 1.2 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 4.1 GO:0007286 spermatid development(GO:0007286)
0.1 1.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.7 GO:0051597 response to methylmercury(GO:0051597)
0.1 3.3 GO:0051923 sulfation(GO:0051923)
0.1 6.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 2.1 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 3.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.1 1.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 1.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 1.3 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 2.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.8 GO:0006868 glutamine transport(GO:0006868)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 0.9 GO:0045682 regulation of epidermis development(GO:0045682)
0.1 1.7 GO:0007634 optokinetic behavior(GO:0007634)
0.1 1.2 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 2.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.4 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.1 2.2 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 3.9 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.3 GO:0030217 T cell differentiation(GO:0030217)
0.0 4.2 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 3.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 2.0 GO:0006096 glycolytic process(GO:0006096)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0048909 anterior lateral line nerve development(GO:0048909) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 1.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 3.8 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.4 GO:0009409 response to cold(GO:0009409)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.3 GO:0051607 defense response to virus(GO:0051607)
0.0 1.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 1.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 4.3 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.1 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 2.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 1.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 1.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 3.3 GO:0048179 activin receptor complex(GO:0048179)
0.2 5.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 8.1 GO:0005861 troponin complex(GO:0005861)
0.1 2.0 GO:0002102 podosome(GO:0002102)
0.1 2.5 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.7 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.7 GO:0031201 SNARE complex(GO:0031201)
0.0 4.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 2.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 10.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.9 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.6 GO:0005912 adherens junction(GO:0005912)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.2 GO:0003796 lysozyme activity(GO:0003796)
0.7 2.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.6 3.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 4.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.5 2.3 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.4 1.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.3 8.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 2.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 2.1 GO:0035173 histone kinase activity(GO:0035173)
0.3 0.9 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.2 0.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.9 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.2 8.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.3 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 3.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 3.4 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.1 1.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 1.3 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 7.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.7 GO:0030332 cyclin binding(GO:0030332)
0.1 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 2.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 4.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 14.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 6.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 2.5 PID ALK2 PATHWAY ALK2 signaling events
0.2 3.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.5 PID AURORA A PATHWAY Aurora A signaling
0.1 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 8.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 6.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 4.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling