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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxm1

Z-value: 0.79

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Transcription factors associated with foxm1

Gene Symbol Gene ID Gene Info
foxm1
ENSDARG00000003200 forkhead box M1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxm1dr11_v1_chr4_-_5831522_58315220.321.7e-03Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_5291012 5.62 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr25_-_22187397 4.82 ENSDART00000123211
ENSDART00000139110
pkp3a
plakophilin 3a
chr16_+_21801277 4.46 ENSDART00000088407
trim108
tripartite motif containing 108
chr3_-_19561058 4.26 ENSDART00000079323
zgc:163079
zgc:163079
chr2_+_11205795 4.17 ENSDART00000019078
lhx8a
LIM homeobox 8a
chr12_+_17154655 4.17 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr24_+_20960216 4.00 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr18_+_17534627 3.41 ENSDART00000061007
mt2
metallothionein 2
chr5_-_24333684 3.22 ENSDART00000051553
znf703
zinc finger protein 703
chr14_-_26177156 3.21 ENSDART00000014149
fat2
FAT atypical cadherin 2
chr22_-_17671348 2.90 ENSDART00000137995
tjp3
tight junction protein 3
chr4_-_68913650 2.86 ENSDART00000184297
si:dkey-264f17.5
si:dkey-264f17.5
chr24_-_20915050 2.81 ENSDART00000133763
si:ch211-161h7.5
si:ch211-161h7.5
chr15_-_23761580 2.80 ENSDART00000137918
bbc3
BCL2 binding component 3
chr24_+_17007407 2.75 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr2_-_29996036 2.64 ENSDART00000020792
cnpy1
canopy1
chr14_+_20893065 2.63 ENSDART00000079452
lygl1
lysozyme g-like 1
chr19_-_340641 2.45 ENSDART00000183848
golph3l
golgi phosphoprotein 3-like
chr9_+_23770666 2.38 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr4_+_15944245 2.30 ENSDART00000134594
si:dkey-117n7.3
si:dkey-117n7.3
chr18_-_15932704 2.28 ENSDART00000127769
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr11_-_3646793 2.26 ENSDART00000077344
itih1
inter-alpha-trypsin inhibitor heavy chain 1
chr5_+_31214341 2.25 ENSDART00000133432
atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr14_-_22015232 2.18 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr14_+_31865099 2.17 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr9_-_38036984 2.16 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr14_+_45559268 2.15 ENSDART00000173152
RARRES3
zgc:154040
chr1_+_59088205 2.13 ENSDART00000150649
ENSDART00000100197
zgc:173915
zgc:173915
chr7_+_26629084 2.02 ENSDART00000101044
ENSDART00000173765
hsbp1a
heat shock factor binding protein 1a
chr3_-_37758487 2.02 ENSDART00000150938
si:dkey-260c8.6
si:dkey-260c8.6
chr7_+_15736230 2.01 ENSDART00000109942
mctp2b
multiple C2 domains, transmembrane 2b
chr13_-_22961605 1.95 ENSDART00000143112
ENSDART00000057641
tspan15
tetraspanin 15
chr20_-_39596338 1.93 ENSDART00000023531
hey2
hes-related family bHLH transcription factor with YRPW motif 2
chr20_-_22798794 1.90 ENSDART00000148084
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr21_+_37436907 1.90 ENSDART00000182611
ENSDART00000076328
pgrmc1
progesterone receptor membrane component 1
chr6_+_40523370 1.88 ENSDART00000033819
prkcda
protein kinase C, delta a
chr5_-_22082918 1.87 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr14_-_8453192 1.84 ENSDART00000136947
eif1ad
eukaryotic translation initiation factor 1A domain containing
chr20_+_25904199 1.84 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr20_+_16881883 1.80 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr11_-_3647014 1.77 ENSDART00000171786
itih1
inter-alpha-trypsin inhibitor heavy chain 1
chr6_+_40922572 1.77 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_-_67757188 1.76 ENSDART00000167168
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr4_-_12718367 1.75 ENSDART00000035259
mgst1.1
microsomal glutathione S-transferase 1.1
chr10_+_22891126 1.72 ENSDART00000057291
arrb2a
arrestin, beta 2a
chr3_+_1167026 1.69 ENSDART00000031823
ENSDART00000155340
triobpb
TRIO and F-actin binding protein b
chr25_-_24202576 1.68 ENSDART00000048507
uevld
UEV and lactate/malate dehyrogenase domains
chr6_-_14040136 1.65 ENSDART00000065361
ENSDART00000179765
etv5b
ets variant 5b
chr22_-_9934854 1.63 ENSDART00000136404
si:dkey-253d23.11
si:dkey-253d23.11
chr16_-_25841084 1.59 ENSDART00000159217
CR391937.1

chr1_-_51038885 1.57 ENSDART00000035150
spast
spastin
chr12_-_9516981 1.52 ENSDART00000106285
si:ch211-207i20.3
si:ch211-207i20.3
chr4_-_890220 1.52 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr22_+_835728 1.51 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr5_-_9948497 1.51 ENSDART00000183196
tor4ab
torsin family 4, member Ab
chr1_+_52137528 1.47 ENSDART00000007079
ENSDART00000074265
asna1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr2_-_39759059 1.45 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr1_+_58370526 1.43 ENSDART00000067775
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr15_+_37589698 1.43 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin37
lin-37 DREAM MuvB core complex component
chr21_-_13856689 1.41 ENSDART00000102197
fam129ba
family with sequence similarity 129, member Ba
chr14_-_33521071 1.41 ENSDART00000052789
c1galt1c1
C1GALT1-specific chaperone 1
chr15_-_41762530 1.39 ENSDART00000187125
ENSDART00000154971
ftr91
finTRIM family, member 91
chr12_-_33558879 1.39 ENSDART00000161167
mbtd1
mbt domain containing 1
chr4_+_25558849 1.39 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
zgc:195175
chr12_+_28888975 1.36 ENSDART00000076362
phkg2
phosphorylase kinase, gamma 2 (testis)
chr8_-_21071476 1.36 ENSDART00000184184
ENSDART00000100288
zgc:112962
zgc:112962
chr14_+_45565891 1.35 ENSDART00000133389
ENSDART00000025549
zgc:92249
zgc:92249
chr19_+_31904836 1.35 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr13_+_31550185 1.33 ENSDART00000127843
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr9_-_31108285 1.33 ENSDART00000003193
gpr183a
G protein-coupled receptor 183a
chr6_-_54444929 1.33 ENSDART00000154121
sys1
Sys1 golgi trafficking protein
chr6_+_18569453 1.32 ENSDART00000171338
rhot1b
ras homolog family member T1
chr2_+_58008980 1.32 ENSDART00000171264
si:ch211-155e24.3
si:ch211-155e24.3
chr7_-_51102479 1.32 ENSDART00000174023
col4a6
collagen, type IV, alpha 6
chr22_+_34615591 1.32 ENSDART00000189563
si:ch1073-214b20.2
si:ch1073-214b20.2
chr3_+_2719243 1.32 ENSDART00000189256
CR388047.3

chr7_-_20836625 1.31 ENSDART00000192566
cldn15a
claudin 15a
chr9_-_38368138 1.30 ENSDART00000059574
ccdc93
coiled-coil domain containing 93
chr13_+_33298338 1.29 ENSDART00000131892
ENSDART00000143895
iqcc
IQ motif containing C
chr18_+_27001115 1.26 ENSDART00000133547
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr6_+_56147812 1.25 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr4_-_43731342 1.25 ENSDART00000146627
si:ch211-226o13.3
si:ch211-226o13.3
chr3_-_49514874 1.21 ENSDART00000167179
asf1ba
anti-silencing function 1Ba histone chaperone
chr12_-_43428542 1.21 ENSDART00000192266
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr14_-_25577094 1.20 ENSDART00000163669
cplx2
complexin 2
chr22_+_17606863 1.20 ENSDART00000035670
polr2eb
polymerase (RNA) II (DNA directed) polypeptide E, b
chr2_-_59231017 1.19 ENSDART00000143980
ENSDART00000184190
ftr29
finTRIM family, member 29
chr4_-_22472653 1.17 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
kmt2e
lysine (K)-specific methyltransferase 2E
chr5_-_51902935 1.17 ENSDART00000182160
mtx3
metaxin 3
chr2_+_31838442 1.16 ENSDART00000066789
stard3nl
STARD3 N-terminal like
chr3_+_1107102 1.15 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr6_-_40922971 1.15 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr4_+_47445318 1.14 ENSDART00000183819
si:dkey-124l13.1
si:dkey-124l13.1
chr20_+_9124369 1.14 ENSDART00000064150
si:ch211-59d15.9
si:ch211-59d15.9
chr4_-_5691257 1.10 ENSDART00000110497
tmem63a
transmembrane protein 63A
chr15_-_14210382 1.09 ENSDART00000179599
CR925813.1

chr19_-_11966015 1.09 ENSDART00000123409
si:ch1073-296d18.1
si:ch1073-296d18.1
chr16_+_40131473 1.09 ENSDART00000155421
ENSDART00000134732
ENSDART00000138699
cenpw
si:ch211-195p4.4
centromere protein W
si:ch211-195p4.4
chr11_-_18017918 1.08 ENSDART00000040171
qrich1
glutamine-rich 1
chr18_+_18439332 1.08 ENSDART00000043843
siah1
siah E3 ubiquitin protein ligase 1
chr6_+_35362225 1.07 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr1_+_55535827 1.07 ENSDART00000152784
adgre16
adhesion G protein-coupled receptor E16
chr15_+_23534126 1.07 ENSDART00000152320
si:dkey-182i3.10
si:dkey-182i3.10
chr11_-_42418374 1.06 ENSDART00000160704
slmapa
sarcolemma associated protein a
chr21_-_23046606 1.06 ENSDART00000016167
zw10
zw10 kinetochore protein
chr17_-_50301313 1.06 ENSDART00000125772
si:ch73-50f9.4
si:ch73-50f9.4
chr10_+_8767541 1.06 ENSDART00000170272
itga1
integrin, alpha 1
chr17_-_7818944 1.06 ENSDART00000135538
ENSDART00000037541
rmnd1
required for meiotic nuclear division 1 homolog
chr11_-_36474306 1.03 ENSDART00000170678
ENSDART00000123591
usp48
ubiquitin specific peptidase 48
chr17_-_21162821 1.03 ENSDART00000157283
abhd12
abhydrolase domain containing 12
chr22_-_17606575 1.03 ENSDART00000183951
gpx4a
glutathione peroxidase 4a
chr16_+_46410520 1.03 ENSDART00000131072
rpz2
rapunzel 2
chr7_-_4125021 1.03 ENSDART00000167182
ENSDART00000173696
zgc:55733
zgc:55733
chr4_+_75577480 1.02 ENSDART00000188196
si:ch211-227e10.1
si:ch211-227e10.1
chr12_+_30234209 1.02 ENSDART00000102081
afap1l2
actin filament associated protein 1-like 2
chr4_-_23839789 1.02 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr8_+_40210398 1.01 ENSDART00000167612
rnf34a
ring finger protein 34a
chr7_+_60359347 1.00 ENSDART00000145201
ENSDART00000039827
ppp1r14bb
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr19_-_46018152 1.00 ENSDART00000159206
krit1
KRIT1, ankyrin repeat containing
chr3_-_33967767 1.00 ENSDART00000151493
ENSDART00000151160
ighv1-4
immunoglobulin heavy variable 1-4
chr14_+_901847 0.98 ENSDART00000166991
si:ch73-208h1.2
si:ch73-208h1.2
chr7_-_13906409 0.98 ENSDART00000062257
slc39a1
solute carrier family 39 (zinc transporter), member 1
chr14_-_16082806 0.98 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr5_-_51903243 0.97 ENSDART00000125535
mtx3
metaxin 3
chr16_+_25068576 0.97 ENSDART00000125838
im:7147486
im:7147486
chr18_+_44768829 0.96 ENSDART00000016271
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr13_+_5978809 0.95 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr3_-_54607166 0.95 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr8_-_22558773 0.94 ENSDART00000074309
porcnl
porcupine O-acyltransferase like
chr7_+_39401388 0.94 ENSDART00000144750
tnni2b.1
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr15_+_47362728 0.93 ENSDART00000180712
CABZ01099833.1

chr8_-_18211605 0.92 ENSDART00000114177
CT025742.1

chr3_+_32714157 0.92 ENSDART00000131774
setd1a
SET domain containing 1A
chr4_-_12718103 0.91 ENSDART00000144388
mgst1.1
microsomal glutathione S-transferase 1.1
chr7_+_4625915 0.90 ENSDART00000108557
si:ch211-225k7.3
si:ch211-225k7.3
chr13_+_44857087 0.89 ENSDART00000017770
zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr4_+_60492313 0.89 ENSDART00000191043
ENSDART00000191631
si:dkey-211i20.2
si:dkey-211i20.2
chr19_-_6134802 0.89 ENSDART00000140051
cica
capicua transcriptional repressor a
chr23_-_14990865 0.88 ENSDART00000147799
ndrg3b
ndrg family member 3b
chr4_-_12388535 0.88 ENSDART00000017180
rergla
RERG/RAS-like a
chr17_+_45639247 0.86 ENSDART00000153669
vcpkmt
valosin containing protein lysine (K) methyltransferase
chr5_-_38197080 0.86 ENSDART00000140708
si:ch211-284e13.9
si:ch211-284e13.9
chr4_+_67999732 0.85 ENSDART00000190597
si:ch211-133h13.1
si:ch211-133h13.1
chr4_+_75537772 0.85 ENSDART00000168380
si:ch211-227e10.1
si:ch211-227e10.1
chr4_+_29702703 0.84 ENSDART00000167771
si:ch211-214c20.1
si:ch211-214c20.1
chr16_+_25809235 0.84 ENSDART00000181196
irgq1
immunity-related GTPase family, q1
chr11_-_28614608 0.84 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr11_-_33618612 0.83 ENSDART00000033980
lims1
LIM and senescent cell antigen-like domains 1
chr20_-_30938184 0.83 ENSDART00000147359
ENSDART00000062552
wtap
WT1 associated protein
chr4_-_60790123 0.82 ENSDART00000137702
si:dkey-254e13.6
si:dkey-254e13.6
chr15_+_29393519 0.82 ENSDART00000193488
ENSDART00000112375
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr5_-_23596339 0.82 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr11_-_18107447 0.81 ENSDART00000187376
qrich1
glutamine-rich 1
chr3_+_60589157 0.81 ENSDART00000165367
mettl23
methyltransferase like 23
chr15_+_23784842 0.81 ENSDART00000192889
ENSDART00000138375
ift20
intraflagellar transport 20 homolog (Chlamydomonas)
chr15_-_37589600 0.80 ENSDART00000154641
proser3
proline and serine rich 3
chr7_+_4572727 0.80 ENSDART00000137830
si:dkey-83f18.7
si:dkey-83f18.7
chr5_+_50898849 0.79 ENSDART00000083317
arsk
arylsulfatase family, member K
chr22_+_5851122 0.79 ENSDART00000082044
zmp:0000001161
zmp:0000001161
chr15_-_23692359 0.76 ENSDART00000141618
ercc2
excision repair cross-complementation group 2
chr19_-_7832439 0.75 ENSDART00000104703
ENSDART00000132336
znf687b
zinc finger protein 687b
chr18_+_27000850 0.75 ENSDART00000188906
ENSDART00000086131
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr16_+_53125918 0.74 ENSDART00000102170
CABZ01053976.1

chr10_+_25272355 0.72 ENSDART00000140186
rab38b
RAB38b, member of RAS oncogene family
chr11_+_44502410 0.72 ENSDART00000172998
ero1b
endoplasmic reticulum oxidoreductase beta
chr17_-_11439815 0.71 ENSDART00000130105
psma3
proteasome subunit alpha 3
chr15_-_20710 0.69 ENSDART00000161218
cyp2y3
cytochrome P450, family 2, subfamily Y, polypeptide 3
chr15_-_44052927 0.67 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr2_-_10338759 0.65 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr1_+_12348213 0.65 ENSDART00000144920
ENSDART00000138759
ENSDART00000067082
clta
clathrin, light chain A
chr1_+_19538299 0.65 ENSDART00000109416
smc2
structural maintenance of chromosomes 2
chr19_+_7759354 0.65 ENSDART00000151400
ubap2l
ubiquitin associated protein 2-like
chr13_+_25421531 0.64 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr18_-_20458412 0.64 ENSDART00000012241
kif23
kinesin family member 23
chr4_+_70171984 0.64 ENSDART00000158100
si:dkey-3h2.4
si:dkey-3h2.4
chr10_-_42237304 0.63 ENSDART00000140341
tcf7l1a
transcription factor 7 like 1a
chr2_+_25840463 0.62 ENSDART00000125178
eif5a2
eukaryotic translation initiation factor 5A2
chr8_+_23147218 0.62 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr3_+_37112693 0.61 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
psmc3ip
PSMC3 interacting protein
chr18_-_20458840 0.60 ENSDART00000177125
kif23
kinesin family member 23
chr22_+_2254972 0.60 ENSDART00000144906
znf1157
zinc finger protein 1157
chr10_+_26834985 0.60 ENSDART00000147518
fam89b
family with sequence similarity 89, member B
chr1_+_40566978 0.59 ENSDART00000137047
ENSDART00000135578
scoca
short coiled-coil protein a
chr1_-_23268569 0.59 ENSDART00000143948
rfc1
replication factor C (activator 1) 1
chr21_-_22812417 0.58 ENSDART00000079151
ENSDART00000112175
trpc6a
transient receptor potential cation channel, subfamily C, member 6a
chr7_+_13995792 0.57 ENSDART00000091470
furina
furin (paired basic amino acid cleaving enzyme) a
chr23_+_39611688 0.57 ENSDART00000034690
otud3
OTU deubiquitinase 3
chr5_+_39099380 0.55 ENSDART00000166657
bmp2k
BMP2 inducible kinase
chr14_-_4177311 0.54 ENSDART00000128129
si:dkey-185e18.7
si:dkey-185e18.7
chr22_+_1734981 0.54 ENSDART00000158195
znf1159
zinc finger protein 1159
chr19_+_18627100 0.54 ENSDART00000167245
vps52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr12_-_48566778 0.53 ENSDART00000063442
cyp4f3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr3_-_37082618 0.53 ENSDART00000026701
ENSDART00000110716
tubg1
tubulin, gamma 1
chr24_+_18948665 0.53 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr14_+_8638353 0.52 ENSDART00000163240
si:dkeyp-115e12.6
si:dkeyp-115e12.6
chr6_-_29288155 0.52 ENSDART00000078630
nme7
NME/NM23 family member 7
chr6_-_19270484 0.52 ENSDART00000186894
ENSDART00000188709
zgc:174863
zgc:174863
chr4_-_36032177 0.52 ENSDART00000170143
zgc:174180
zgc:174180
chr17_+_10593398 0.51 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr9_+_22780901 0.50 ENSDART00000110992
ENSDART00000143972
rif1
replication timing regulatory factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 1.9 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.6 1.9 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.6 1.8 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.6 2.8 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.5 1.6 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.5 5.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 1.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.4 1.3 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.4 1.7 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.4 2.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.4 3.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.4 1.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.3 1.0 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.3 1.0 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.3 2.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 0.9 GO:0061355 Wnt protein secretion(GO:0061355)
0.3 1.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 2.9 GO:0030104 water homeostasis(GO:0030104)
0.3 1.4 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.3 1.1 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.2 1.0 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.2 3.4 GO:0010573 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575)
0.2 1.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 1.0 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 1.8 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 0.8 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.2 0.9 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 2.0 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 1.2 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 4.2 GO:0021884 forebrain neuron development(GO:0021884)
0.2 0.8 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.4 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 1.0 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:1903429 regulation of cell maturation(GO:1903429)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.2 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.1 2.2 GO:0010821 regulation of mitochondrion organization(GO:0010821)
0.1 1.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.3 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.8 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.6 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 2.2 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.1 2.6 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.1 3.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.3 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.3 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.9 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.3 GO:0090559 regulation of membrane permeability(GO:0090559)
0.0 1.1 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 6.1 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.5 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 1.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.9 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.6 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.7 GO:0032438 melanosome organization(GO:0032438)
0.0 0.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 3.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.7 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.5 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 0.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.4 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 1.1 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0003231 cardiac ventricle development(GO:0003231)
0.0 2.1 GO:0051604 protein maturation(GO:0051604)
0.0 2.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.8 GO:0003401 axis elongation(GO:0003401)
0.0 0.9 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 2.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005948 acetolactate synthase complex(GO:0005948)
0.3 4.8 GO:0030057 desmosome(GO:0030057)
0.2 1.9 GO:0001772 immunological synapse(GO:0001772)
0.2 1.3 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.8 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 3.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.4 GO:0035101 FACT complex(GO:0035101)
0.1 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 0.8 GO:0014704 intercalated disc(GO:0014704)
0.1 4.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.0 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 2.2 GO:0000776 kinetochore(GO:0000776)
0.0 1.1 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 2.8 GO:0005912 adherens junction(GO:0005912) anchoring junction(GO:0070161)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.7 2.6 GO:0003796 lysozyme activity(GO:0003796)
0.6 1.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.5 2.2 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.5 1.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 1.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 1.4 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.3 1.0 GO:0003984 acetolactate synthase activity(GO:0003984)
0.3 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 2.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 2.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 2.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 3.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.5 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 2.3 GO:0045296 cadherin binding(GO:0045296)
0.0 4.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 6.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0043022 translation elongation factor activity(GO:0003746) ribosome binding(GO:0043022)
0.0 0.9 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.1 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 4.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.7 PID AURORA B PATHWAY Aurora B signaling
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.3 REACTOME KINESINS Genes involved in Kinesins
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress