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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxn1

Z-value: 0.82

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Transcription factors associated with foxn1

Gene Symbol Gene ID Gene Info
foxn1
ENSDARG00000011879 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxn1dr11_v1_chr15_-_28148314_28148314-0.122.5e-01Click!

Activity profile of foxn1 motif

Sorted Z-values of foxn1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_19103490 5.79 ENSDART00000060561
csdc2a
cold shock domain containing C2, RNA binding a
chr13_+_51579851 5.37 ENSDART00000163847
nkx6.2
NK6 homeobox 2
chr23_+_19590006 4.92 ENSDART00000021231
slmapb
sarcolemma associated protein b
chr7_+_23907692 4.80 ENSDART00000045479
syt4
synaptotagmin IV
chr3_-_35602233 4.73 ENSDART00000055269
gng13b
guanine nucleotide binding protein (G protein), gamma 13b
chr3_+_33340939 4.62 ENSDART00000128786
pyya
peptide YYa
chr24_-_29997145 4.41 ENSDART00000135094
palmdb
palmdelphin b
chr19_-_21832441 4.39 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
mbpa
myelin basic protein a
chr14_+_8275115 4.29 ENSDART00000129055
nrg2b
neuregulin 2b
chr25_+_12640211 4.26 ENSDART00000165108
jph3
junctophilin 3
chr1_+_19930520 4.23 ENSDART00000158344
apbb2b
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr10_+_21668606 4.16 ENSDART00000185751
CT737184.2

chr4_+_2619132 4.03 ENSDART00000128807
gpr22a
G protein-coupled receptor 22a
chr8_+_6967108 3.95 ENSDART00000004588
asic1a
acid-sensing (proton-gated) ion channel 1a
chr17_-_46457622 3.81 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr12_+_26467847 3.81 ENSDART00000022495
ndel1a
nudE neurodevelopment protein 1-like 1a
chr17_-_45552602 3.74 ENSDART00000154844
ENSDART00000034432
susd4
sushi domain containing 4
chr21_-_35325466 3.70 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr7_+_23495986 3.65 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr5_-_29643381 3.42 ENSDART00000034849
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr23_-_27345425 3.39 ENSDART00000022042
ENSDART00000191870
scn8aa
sodium channel, voltage gated, type VIII, alpha subunit a
chr17_+_44780166 3.33 ENSDART00000156260
tmem63c
transmembrane protein 63C
chr2_-_2096055 3.32 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr17_+_29345606 3.26 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr15_-_22147860 3.18 ENSDART00000149784
scn3b
sodium channel, voltage-gated, type III, beta
chr12_-_35988586 3.15 ENSDART00000157746
pde6gb
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b
chr10_+_37500234 3.13 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr20_-_4738101 3.12 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
papola
poly(A) polymerase alpha
chr5_-_31901468 3.09 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr13_-_51247529 3.07 ENSDART00000191774
ENSDART00000083788
AL929217.1

chr19_-_27966526 3.06 ENSDART00000141896
ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr20_-_28884800 3.05 ENSDART00000134564
ENSDART00000132127
ENSDART00000135506
ENSDART00000075515
srsf5b
serine/arginine-rich splicing factor 5b
chr1_+_34203817 3.02 ENSDART00000191432
ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr12_+_9703172 2.99 ENSDART00000091489
ppp1r9bb
protein phosphatase 1, regulatory subunit 9Bb
chr6_-_42377307 2.98 ENSDART00000129302
emc3
ER membrane protein complex subunit 3
chr15_-_15449929 2.97 ENSDART00000101918
proca1
protein interacting with cyclin A1
chr5_-_52216170 2.96 ENSDART00000158542
ENSDART00000192981
lnpep
leucyl/cystinyl aminopeptidase
chr8_-_25846188 2.95 ENSDART00000128829
efhd2
EF-hand domain family, member D2
chr21_-_14251306 2.94 ENSDART00000114715
ENSDART00000181380
man1b1a
mannosidase, alpha, class 1B, member 1a
chr4_-_12102025 2.93 ENSDART00000048391
ENSDART00000023894
braf
B-Raf proto-oncogene, serine/threonine kinase
chr18_-_39787040 2.87 ENSDART00000169916
dmxl2
Dmx-like 2
chr21_-_43606502 2.84 ENSDART00000151030
si:ch73-362m14.4
si:ch73-362m14.4
chr18_+_328689 2.83 ENSDART00000167841
ss18l2
synovial sarcoma translocation gene on chromosome 18-like 2
chr16_+_50741154 2.74 ENSDART00000101627
IGLON5
zgc:110372
chr1_-_21483832 2.73 ENSDART00000102790
glrba
glycine receptor, beta a
chr13_+_24287093 2.71 ENSDART00000058628
ccsapb
centriole, cilia and spindle-associated protein b
chr8_+_35172594 2.70 ENSDART00000177146
BX897670.1

chr17_-_7861219 2.68 ENSDART00000148604
syne1b
spectrin repeat containing, nuclear envelope 1b
chr9_-_48296469 2.66 ENSDART00000058255
bbs5
Bardet-Biedl syndrome 5
chr1_+_33969015 2.63 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr20_-_6196989 2.62 ENSDART00000013343
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr9_-_28399071 2.58 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr1_-_6494384 2.54 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr16_+_23531583 2.51 ENSDART00000146708
adar
adenosine deaminase, RNA-specific
chr11_+_6819050 2.47 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr17_+_37301860 2.45 ENSDART00000181531
ENSDART00000075978
elmsan1b
ELM2 and Myb/SANT-like domain containing 1b
chr15_+_15516612 2.38 ENSDART00000016024
traf4a
tnf receptor-associated factor 4a
chr2_+_42871831 2.36 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr14_-_2361692 2.32 ENSDART00000167696
PCDHGC3 (1 of many)
si:ch73-233f7.4
chr5_+_11812089 2.30 ENSDART00000111359
fbxo21
F-box protein 21
chr1_+_34295925 2.28 ENSDART00000075584
kctd12.2
potassium channel tetramerisation domain containing 12.2
chr25_-_25142387 2.27 ENSDART00000031814
tsg101a
tumor susceptibility 101a
chr11_-_5563498 2.26 ENSDART00000160835
pex11g
peroxisomal biogenesis factor 11 gamma
chr19_+_5135113 2.21 ENSDART00000151310
si:dkey-89b17.4
si:dkey-89b17.4
chr16_-_7362806 2.19 ENSDART00000166776
foxo6a
forkhead box O6 a
chr1_+_40237276 2.17 ENSDART00000037553
faah2a
fatty acid amide hydrolase 2a
chr16_-_6205790 2.15 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr7_+_21859337 2.11 ENSDART00000159626
si:dkey-85k7.7
si:dkey-85k7.7
chr13_+_35925490 2.10 ENSDART00000046115
mfsd2aa
major facilitator superfamily domain containing 2aa
chr19_+_5134624 2.09 ENSDART00000151324
si:dkey-89b17.4
si:dkey-89b17.4
chr21_+_21279159 2.09 ENSDART00000148346
itpkca
inositol-trisphosphate 3-kinase Ca
chr24_-_38374744 2.08 ENSDART00000007208
lrrc4bb
leucine rich repeat containing 4Bb
chr5_+_26075230 2.05 ENSDART00000098473
klf9
Kruppel-like factor 9
chr9_+_21793565 2.05 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr10_+_36695597 2.05 ENSDART00000169015
ENSDART00000171392
rab6a
RAB6A, member RAS oncogene family
chr4_-_8152746 2.03 ENSDART00000012928
ENSDART00000177482
wnk1b
WNK lysine deficient protein kinase 1b
chr1_+_31725154 1.99 ENSDART00000112333
ENSDART00000189801
cnnm2b
cyclin and CBS domain divalent metal cation transport mediator 2b
chr2_-_16359042 1.96 ENSDART00000057216
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr23_-_10786400 1.92 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr23_+_23485858 1.88 ENSDART00000114067
agrn
agrin
chr19_-_27966780 1.87 ENSDART00000110016
ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr11_-_38083397 1.85 ENSDART00000086516
ENSDART00000184033
klhdc8a
kelch domain containing 8A
chr21_+_3093419 1.84 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr11_+_23933016 1.82 ENSDART00000000486
cntn2
contactin 2
chr2_+_37480669 1.78 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr16_-_31351419 1.77 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr4_-_1497384 1.74 ENSDART00000093236
zmp:0000000711
zmp:0000000711
chr7_+_22801465 1.72 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr20_-_31808779 1.71 ENSDART00000133788
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr7_-_12869545 1.70 ENSDART00000163045
sh3gl3a
SH3-domain GRB2-like 3a
chr6_-_37469775 1.68 ENSDART00000156546
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr12_-_13318944 1.68 ENSDART00000152201
ENSDART00000041394
emc9
ER membrane protein complex subunit 9
chr11_-_22371105 1.67 ENSDART00000146873
tmem183a
transmembrane protein 183A
chr6_+_39493864 1.66 ENSDART00000086263
mettl7a
methyltransferase like 7A
chr19_+_26681848 1.64 ENSDART00000138322
si:dkey-27c15.3
si:dkey-27c15.3
chr8_+_52530889 1.64 ENSDART00000127729
ENSDART00000170360
ENSDART00000162687
stambpb
STAM binding protein b
chr5_-_19932621 1.64 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr22_-_11614973 1.63 ENSDART00000063135
pcyt2
phosphate cytidylyltransferase 2, ethanolamine
chr8_-_43158486 1.62 ENSDART00000134801
ccdc92
coiled-coil domain containing 92
chr13_+_18321140 1.62 ENSDART00000180947
eif4e1c
eukaryotic translation initiation factor 4E family member 1c
chr3_-_32180796 1.61 ENSDART00000133191
ENSDART00000055308
pih1d1
PIH1 domain containing 1
chr7_+_17782436 1.61 ENSDART00000173793
ENSDART00000165110
si:dkey-28a3.2
si:dkey-28a3.2
chr9_-_24046287 1.60 ENSDART00000184313
ackr3a
atypical chemokine receptor 3a
chr1_-_45041272 1.60 ENSDART00000190615
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr3_+_34919810 1.57 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr15_-_23908779 1.56 ENSDART00000088808
usp32
ubiquitin specific peptidase 32
chr23_-_35347714 1.55 ENSDART00000161770
ENSDART00000165615
cpne9
copine family member IX
chr5_-_52215926 1.55 ENSDART00000163973
ENSDART00000193602
lnpep
leucyl/cystinyl aminopeptidase
chr21_+_21743599 1.54 ENSDART00000101700
pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr11_-_19694334 1.53 ENSDART00000054735
SYNPR
si:dkey-30j16.3
chr13_-_27916439 1.53 ENSDART00000139081
ENSDART00000087097
ogfrl1
opioid growth factor receptor-like 1
chr2_-_56131312 1.53 ENSDART00000097755
jund
JunD proto-oncogene, AP-1 transcription factor subunit
chr5_+_1219187 1.48 ENSDART00000129490
gb:bc139872
expressed sequence BC139872
chr1_+_41690402 1.47 ENSDART00000177298
fbxo41
F-box protein 41
chr5_-_54554583 1.45 ENSDART00000158865
ENSDART00000158069
ssna1
Sjogren syndrome nuclear autoantigen 1
chr21_+_1119046 1.43 ENSDART00000184678
CABZ01088049.1

chr12_-_10674606 1.43 ENSDART00000157919
med24
mediator complex subunit 24
chr15_+_2421432 1.41 ENSDART00000193772
hephl1a
hephaestin-like 1a
chr16_+_26547152 1.41 ENSDART00000141393
ptpn3
protein tyrosine phosphatase, non-receptor type 3
chr13_-_21650404 1.39 ENSDART00000078352
tspan14
tetraspanin 14
chr24_+_19210001 1.38 ENSDART00000179373
ENSDART00000139299
zgc:162928
zgc:162928
chr2_+_16696052 1.37 ENSDART00000022356
ENSDART00000164329
ppp1r7
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr17_+_10593398 1.36 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr8_-_24113575 1.36 ENSDART00000099692
ENSDART00000186211
dclre1b
DNA cross-link repair 1B
chr12_+_49100365 1.34 ENSDART00000171905
CABZ01075125.1

chr6_-_29612269 1.32 ENSDART00000104293
pex5la
peroxisomal biogenesis factor 5-like a
chr15_-_6976851 1.32 ENSDART00000158474
ENSDART00000168943
ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr17_+_43032529 1.32 ENSDART00000055611
ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr11_-_23687158 1.31 ENSDART00000189599
pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr10_+_29137482 1.30 ENSDART00000178280
picalma
phosphatidylinositol binding clathrin assembly protein a
chr7_-_19146925 1.29 ENSDART00000142924
ENSDART00000009695
kirrel1a
kirre like nephrin family adhesion molecule 1a
chr24_+_4373355 1.28 ENSDART00000179062
ENSDART00000093256
ENSDART00000138943
ccny
cyclin Y
chr8_+_668184 1.28 ENSDART00000183788
rnf165b
ring finger protein 165b
chr22_+_1786230 1.28 ENSDART00000169318
ENSDART00000164948
znf1154
zinc finger protein 1154
chr3_-_22216771 1.27 ENSDART00000130546
maptb
microtubule-associated protein tau b
chr13_+_1439152 1.27 ENSDART00000159047
si:ch211-165e15.1
si:ch211-165e15.1
chr7_-_47850702 1.27 ENSDART00000109511
si:ch211-186j3.6
si:ch211-186j3.6
chr18_+_19990412 1.24 ENSDART00000155054
ENSDART00000090310
pias1b
protein inhibitor of activated STAT, 1b
chr16_+_32136550 1.23 ENSDART00000147526
sphk2
sphingosine kinase 2
chr4_-_73049281 1.22 ENSDART00000169165
LO018021.1

chr15_-_40267485 1.22 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr12_-_4632519 1.20 ENSDART00000110514
prr12a
proline rich 12a
chr7_+_24006875 1.19 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr21_-_14175838 1.18 ENSDART00000111659
whrna
whirlin a
chr18_-_5103931 1.18 ENSDART00000188091
pdcd10a
programmed cell death 10a
chr6_-_35106425 1.16 ENSDART00000165139
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr8_+_36500061 1.16 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr8_-_37043900 1.15 ENSDART00000139567
renbp
renin binding protein
chr3_+_17951790 1.15 ENSDART00000164663
aclya
ATP citrate lyase a
chr17_-_53022822 1.15 ENSDART00000103434
zgc:154061
zgc:154061
chr8_-_18582922 1.15 ENSDART00000123917
tmem47
transmembrane protein 47
chr10_-_43928937 1.15 ENSDART00000168014
ENSDART00000086220
mctp1b
multiple C2 domains, transmembrane 1b
chr15_+_2421729 1.14 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr6_+_51932267 1.14 ENSDART00000156256
angpt4
angiopoietin 4
chr16_-_2390931 1.13 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr17_-_23895026 1.11 ENSDART00000122108
pdzd8
PDZ domain containing 8
chr12_+_19320657 1.10 ENSDART00000100075
ENSDART00000066389
tmem184ba
transmembrane protein 184ba
chr6_+_20647155 1.09 ENSDART00000193477
slc19a1
solute carrier family 19 (folate transporter), member 1
chr15_+_19335646 1.09 ENSDART00000062569
acad8
acyl-CoA dehydrogenase family, member 8
chr6_+_34038963 1.09 ENSDART00000057732
ENSDART00000192496
ap1m3
adaptor-related protein complex 1, mu 3 subunit
chr19_+_29303847 1.08 ENSDART00000009149
maco1a
macoilin 1a
chr1_-_50791280 1.06 ENSDART00000181224
CABZ01031870.1

chr10_-_36825984 1.05 ENSDART00000111104
phf12a
PHD finger protein 12a
chr8_+_18010978 1.03 ENSDART00000039887
ENSDART00000144532
ssbp3b
single stranded DNA binding protein 3b
chr4_+_76441200 1.02 ENSDART00000125751
si:dkey-16p6.1
si:dkey-16p6.1
chr20_+_52442870 1.01 ENSDART00000163100
arhgap39
Rho GTPase activating protein 39
chr1_-_41982582 1.00 ENSDART00000014678
adra1d
adrenoceptor alpha 1D
chr8_-_21071711 1.00 ENSDART00000111600
ENSDART00000135204
ENSDART00000131371
ENSDART00000146532
ENSDART00000137606
zgc:112962
zgc:112962
chr10_+_42374957 0.98 ENSDART00000147926
COX5B
zgc:86599
chr9_-_785444 0.98 ENSDART00000012506
en1a
engrailed homeobox 1a
chr18_-_16937008 0.95 ENSDART00000100117
ENSDART00000022640
ENSDART00000136541
znf143b
zinc finger protein 143b
chr6_+_33885828 0.92 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr6_+_10450000 0.92 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr13_+_19884631 0.90 ENSDART00000089533
atrnl1a
attractin-like 1a
chr6_-_45949121 0.90 ENSDART00000058555
tardbp
TAR DNA binding protein
chr6_+_6491013 0.87 ENSDART00000140827
bcl11ab
B cell CLL/lymphoma 11Ab
chr24_-_18179535 0.87 ENSDART00000186112
cntnap2a
contactin associated protein like 2a
chr20_+_54333774 0.86 ENSDART00000144633
cipcb
CLOCK-interacting pacemaker b
chr17_+_38476300 0.85 ENSDART00000123298
stard9
StAR-related lipid transfer (START) domain containing 9
chr25_+_36405021 0.85 ENSDART00000152801
ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr4_+_12013043 0.85 ENSDART00000130692
cry1aa
cryptochrome circadian clock 1aa
chr1_+_44523516 0.85 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr3_+_15773991 0.84 ENSDART00000089923
znf652
zinc finger protein 652
chr18_+_16715864 0.84 ENSDART00000079758
eif4g2b
eukaryotic translation initiation factor 4, gamma 2b
chr2_+_22531185 0.83 ENSDART00000171959
hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr20_-_18915376 0.83 ENSDART00000063725
xkr6b
XK, Kell blood group complex subunit-related family, member 6b
chr19_+_10473612 0.81 ENSDART00000125718
si:ch211-171h4.7
si:ch211-171h4.7
chr8_-_21071476 0.81 ENSDART00000184184
ENSDART00000100288
zgc:112962
zgc:112962
chr22_-_6651382 0.81 ENSDART00000124308
si:ch211-209l18.4
si:ch211-209l18.4
chr22_-_38459316 0.80 ENSDART00000149683
ENSDART00000098461
ptk7a
protein tyrosine kinase 7a
chr8_+_18010568 0.80 ENSDART00000121984
ssbp3b
single stranded DNA binding protein 3b
chr6_+_7977611 0.80 ENSDART00000112290
palm3
paralemmin 3
chr5_+_23045096 0.80 ENSDART00000171719
atrxl
alpha thalassemia/mental retardation syndrome X-linked, like
chr6_+_59832786 0.79 ENSDART00000154985
ENSDART00000102148
ddx3b
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr9_-_2594410 0.78 ENSDART00000188306
ENSDART00000164276
sp9
sp9 transcription factor
chr8_-_5220125 0.76 ENSDART00000035676
bnip3la
BCL2 interacting protein 3 like a
chr5_+_36415978 0.76 ENSDART00000084464
fam155b
family with sequence similarity 155, member B
chr9_-_41090048 0.75 ENSDART00000131681
ENSDART00000182552
asnsd1
asparagine synthetase domain containing 1
chr7_-_29571615 0.75 ENSDART00000019140
rorab
RAR-related orphan receptor A, paralog b
chr5_+_35463688 0.75 ENSDART00000142525
ENSDART00000131286
erlin2
ER lipid raft associated 2

Network of associatons between targets according to the STRING database.

First level regulatory network of foxn1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
1.0 2.9 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.8 3.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.8 2.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.8 3.2 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.7 2.1 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.7 2.7 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.6 3.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.6 1.9 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.6 1.8 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.6 2.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.6 4.0 GO:0070207 protein homotrimerization(GO:0070207)
0.5 2.7 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.5 3.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.5 2.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.5 1.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.5 2.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.5 2.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.4 6.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 4.7 GO:0050909 sensory perception of taste(GO:0050909)
0.4 3.0 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.4 1.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.4 2.3 GO:0016559 peroxisome fission(GO:0016559)
0.4 1.1 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.4 1.1 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.4 1.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 5.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.3 2.6 GO:0021634 optic nerve formation(GO:0021634)
0.3 1.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.3 1.4 GO:0031627 telomeric loop formation(GO:0031627)
0.3 1.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.3 0.8 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2 1.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 1.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 0.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 1.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 0.9 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.2 3.0 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 2.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 1.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 3.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 2.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 2.0 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.9 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 4.6 GO:0007631 feeding behavior(GO:0007631)
0.2 0.8 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 4.5 GO:0043171 peptide catabolic process(GO:0043171)
0.2 1.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 4.0 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 1.0 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 1.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.3 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 2.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.0 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 2.6 GO:0006825 copper ion transport(GO:0006825)
0.1 3.1 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 4.8 GO:0061512 protein localization to cilium(GO:0061512)
0.1 6.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 2.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 2.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.5 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.5 GO:0046329 negative regulation of JUN kinase activity(GO:0043508) negative regulation of JNK cascade(GO:0046329)
0.1 2.3 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.6 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 3.0 GO:0003094 glomerular filtration(GO:0003094)
0.1 5.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 1.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.8 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.5 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 1.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.3 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.2 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.7 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.9 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.9 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 1.7 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.6 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.2 GO:1903573 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 2.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 1.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 3.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 4.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.6 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 2.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 2.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 3.3 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 4.8 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.9 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.6 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.7 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.3 GO:0015908 fatty acid transport(GO:0015908)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0043291 RAVE complex(GO:0043291)
0.7 2.7 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.5 3.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 1.8 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.4 4.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 6.5 GO:0031209 SCAR complex(GO:0031209)
0.4 1.6 GO:0097255 R2TP complex(GO:0097255)
0.4 1.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.4 2.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.3 2.7 GO:0034464 BBSome(GO:0034464)
0.3 1.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 2.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 1.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.3 6.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 4.4 GO:0043209 myelin sheath(GO:0043209)
0.2 3.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.2 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.1 2.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.1 GO:0005844 polysome(GO:0005844)
0.1 1.2 GO:0060170 ciliary membrane(GO:0060170)
0.1 3.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 4.7 GO:0005871 kinesin complex(GO:0005871)
0.1 2.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 3.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 1.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 8.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 4.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0016234 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.6 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 2.4 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 2.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.9 2.6 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.8 4.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.8 3.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.7 6.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 1.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.4 3.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 1.1 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.3 3.0 GO:0032977 membrane insertase activity(GO:0032977)
0.3 2.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 2.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3 4.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 3.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 2.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 4.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 1.5 GO:0004985 opioid receptor activity(GO:0004985)
0.2 4.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 3.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 2.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 3.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 4.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 2.0 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 1.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.7 GO:0045159 myosin II binding(GO:0045159)
0.1 4.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 2.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 4.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 3.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.9 GO:0043236 laminin binding(GO:0043236)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 5.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.1 GO:0031267 small GTPase binding(GO:0031267)
0.0 4.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 3.8 GO:0042277 peptide binding(GO:0042277)
0.0 4.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 8.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 5.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0051879 Hsp70 protein binding(GO:0030544) Hsp90 protein binding(GO:0051879)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.0 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.6 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 2.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.6 GO:0004536 deoxyribonuclease activity(GO:0004536)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 4.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.7 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 2.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 3.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.8 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 3.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules