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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for gata3

Z-value: 2.02

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Transcription factors associated with gata3

Gene Symbol Gene ID Gene Info
gata3
ENSDARG00000016526 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata3dr11_v1_chr4_-_25064510_250645100.151.4e-01Click!

Activity profile of gata3 motif

Sorted Z-values of gata3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_49159207 75.81 ENSDART00000041942
tspan2a
tetraspanin 2a
chr20_+_9828769 47.25 ENSDART00000160480
ENSDART00000053844
ENSDART00000080691
stxbp6l
syntaxin binding protein 6 (amisyn), like
chr16_-_29437373 42.97 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr7_+_13382852 32.95 ENSDART00000166318
dagla
diacylglycerol lipase, alpha
chr21_-_43079161 32.30 ENSDART00000144151
jakmip2
janus kinase and microtubule interacting protein 2
chr15_+_40008370 29.99 ENSDART00000063783
itm2ca
integral membrane protein 2Ca
chr19_-_32710922 29.57 ENSDART00000004034
hpca
hippocalcin
chr12_+_5189776 28.71 ENSDART00000081298
lgi1b
leucine-rich, glioma inactivated 1b
chr9_-_35557397 28.10 ENSDART00000100681
ncam2
neural cell adhesion molecule 2
chr7_-_13381129 27.00 ENSDART00000164326
si:ch73-119p20.1
si:ch73-119p20.1
chr11_+_36989696 26.62 ENSDART00000045888
tkta
transketolase a
chr20_-_4766645 25.89 ENSDART00000147071
ENSDART00000152398
ak7a
adenylate kinase 7a
chr25_-_11088839 25.29 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr21_+_24287403 24.35 ENSDART00000111169
cadm1a
cell adhesion molecule 1a
chr7_-_24699985 24.11 ENSDART00000052802
calb2b
calbindin 2b
chr13_-_46991577 23.45 ENSDART00000114748
vip
vasoactive intestinal peptide
chr16_-_35532937 23.15 ENSDART00000193209
ctps1b
CTP synthase 1b
chr14_+_6546516 22.73 ENSDART00000097214
adam19b
ADAM metallopeptidase domain 19b
chr17_-_37214196 21.97 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr14_+_50770537 21.96 ENSDART00000158723
sncb
synuclein, beta
chr12_+_28986308 21.67 ENSDART00000153178
si:rp71-1c10.8
si:rp71-1c10.8
chr11_+_34824099 21.54 ENSDART00000037017
ENSDART00000146944
slc38a3a
solute carrier family 38, member 3a
chr25_-_19433244 21.17 ENSDART00000154778
map1ab
microtubule-associated protein 1Ab
chr25_+_7461624 20.97 ENSDART00000170569
syt12
synaptotagmin XII
chr23_-_39849155 19.77 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr11_-_1131569 19.48 ENSDART00000173228
slc6a11b
solute carrier family 6 (neurotransmitter transporter), member 11b
chr17_-_21280185 18.83 ENSDART00000123198
hspa12a
heat shock protein 12A
chr19_-_36675023 18.15 ENSDART00000132471
csmd2
CUB and Sushi multiple domains 2
chr15_-_16704417 17.48 ENSDART00000155163
caln1
calneuron 1
chr7_+_24049776 16.98 ENSDART00000166559
efs
embryonal Fyn-associated substrate
chr5_-_2282256 16.83 ENSDART00000064012
ca4a
carbonic anhydrase IV a
chr6_-_15604157 16.00 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr9_-_51370293 15.04 ENSDART00000084806
slc4a10b
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr19_+_12444943 14.95 ENSDART00000135706
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr9_+_29603649 14.74 ENSDART00000140477
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr4_+_6643421 14.67 ENSDART00000099462
gpr85
G protein-coupled receptor 85
chr15_-_15357178 14.30 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr17_-_8173380 13.91 ENSDART00000148520
syne1b
spectrin repeat containing, nuclear envelope 1b
chr6_-_15604417 13.89 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr5_+_44655148 13.55 ENSDART00000124059
dapk1
death-associated protein kinase 1
chr21_+_43561650 13.52 ENSDART00000085071
gpr185a
G protein-coupled receptor 185 a
chr3_-_15352303 13.13 ENSDART00000104338
ENSDART00000145919
ENSDART00000132135
pitpnbl
phosphatidylinositol transfer protein, beta, like
chr10_-_31175744 13.05 ENSDART00000191728
pknox2
pbx/knotted 1 homeobox 2
chr14_-_32016615 12.83 ENSDART00000105761
zic3
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr5_-_11943750 12.44 ENSDART00000074979
rnft2
ring finger protein, transmembrane 2
chr18_-_34143189 12.43 ENSDART00000079341
plch1
phospholipase C, eta 1
chr7_-_37622370 12.35 ENSDART00000173523
nkd1
naked cuticle homolog 1 (Drosophila)
chr25_+_32157326 12.29 ENSDART00000112588
tjp1b
tight junction protein 1b
chr10_-_2527342 11.98 ENSDART00000184168
CU856539.1

chr11_-_36020005 11.26 ENSDART00000031993
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr11_-_2700397 11.14 ENSDART00000082511
si:ch211-160o17.6
si:ch211-160o17.6
chr7_+_50053339 11.14 ENSDART00000174308
LRRC4C (1 of many)
si:dkey-6l15.1
chr22_+_15507218 11.06 ENSDART00000125450
gpc1a
glypican 1a
chr4_+_4267451 11.05 ENSDART00000192069
ano2
anoctamin 2
chr20_-_9462433 10.88 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr6_+_37623693 10.79 ENSDART00000144812
ENSDART00000182709
tubgcp5
tubulin, gamma complex associated protein 5
chr1_-_23557877 10.72 ENSDART00000145942
fam184b
family with sequence similarity 184, member B
chr6_+_54142311 10.55 ENSDART00000154115
hmga1b
high mobility group AT-hook 1b
chr19_-_3092493 10.53 ENSDART00000184800
si:ch211-80h18.1
si:ch211-80h18.1
chr5_+_44654535 10.46 ENSDART00000182190
ENSDART00000181872
dapk1
death-associated protein kinase 1
chr7_-_52334840 10.44 ENSDART00000174173
CR938716.1

chr16_-_13730152 10.29 ENSDART00000138772
ttyh1
tweety family member 1
chr10_+_22003750 10.16 ENSDART00000109420
kcnip1b
Kv channel interacting protein 1 b
chr23_-_41762956 9.82 ENSDART00000128302
stk35
serine/threonine kinase 35
chr3_-_13146631 9.80 ENSDART00000172460
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr15_-_33896159 9.69 ENSDART00000159791
mag
myelin associated glycoprotein
chr13_+_35745572 9.66 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr7_-_72067475 9.66 ENSDART00000017763
LO018380.1

chr17_+_15033822 9.66 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr14_+_7140997 9.31 ENSDART00000170994
ENSDART00000129898
ctsf
cathepsin F
chr14_+_4276394 9.20 ENSDART00000038301
gnpda2
glucosamine-6-phosphate deaminase 2
chr4_+_4889257 9.16 ENSDART00000175651
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr6_-_9792004 9.09 ENSDART00000081129
cdk15
cyclin-dependent kinase 15
chr17_+_28882977 8.98 ENSDART00000153937
prkd1
protein kinase D1
chr6_+_45346808 8.85 ENSDART00000186327
LO017951.1

chr4_-_14315855 8.82 ENSDART00000133325
nell2b
neural EGFL like 2b
chr2_+_47623202 8.82 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr2_+_9552456 8.73 ENSDART00000056896
dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr11_+_25735478 8.63 ENSDART00000103566
si:dkey-183j2.10
si:dkey-183j2.10
chr7_-_48173440 8.49 ENSDART00000124075
mtss1lb
metastasis suppressor 1-like b
chr21_-_43022048 8.36 ENSDART00000138329
dpysl3
dihydropyrimidinase-like 3
chr14_-_36397768 8.16 ENSDART00000185199
ENSDART00000052562
spata4
spermatogenesis associated 4
chr8_+_26859639 8.13 ENSDART00000133440
prdm2a
PR domain containing 2, with ZNF domain a
chr3_-_21137362 8.09 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr10_-_5568379 8.04 ENSDART00000164558
ENSDART00000005292
syk
spleen tyrosine kinase
chr18_+_16963881 7.97 ENSDART00000147583
si:ch211-242e8.1
si:ch211-242e8.1
chr14_-_30642819 7.90 ENSDART00000078154
npas4a
neuronal PAS domain protein 4a
chr12_+_36413886 7.81 ENSDART00000126325
si:ch211-250n8.1
si:ch211-250n8.1
chr1_-_14258409 7.74 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr17_+_50524573 7.68 ENSDART00000187974
CR382385.1

chr9_+_38962017 7.63 ENSDART00000140436
map2
microtubule-associated protein 2
chr14_-_1565317 7.45 ENSDART00000169496
CABZ01064248.1

chr18_+_3169579 7.45 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr23_-_19953089 7.29 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr16_-_52736549 7.25 ENSDART00000146607
azin1a
antizyme inhibitor 1a
chr19_-_45985989 7.15 ENSDART00000165897
si:ch211-153f2.3
si:ch211-153f2.3
chr2_+_48303142 7.12 ENSDART00000023040
hes6
hes family bHLH transcription factor 6
chr17_-_20897250 7.09 ENSDART00000088106
ank3b
ankyrin 3b
chr6_-_29105727 7.06 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr23_-_16692312 7.04 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr10_+_44581378 7.03 ENSDART00000190331
sez6l
seizure related 6 homolog (mouse)-like
chr25_+_336503 6.91 ENSDART00000160395
CU929262.1

chr20_-_40119872 6.82 ENSDART00000191569
nkain2
sodium/potassium transporting ATPase interacting 2
chr11_+_34824262 6.80 ENSDART00000103157
slc38a3a
solute carrier family 38, member 3a
chr17_+_26569601 6.78 ENSDART00000153897
ndnfl
neuron-derived neurotrophic factor , like
chr17_+_32343121 6.74 ENSDART00000156051
dhx32b
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr4_-_20051141 6.71 ENSDART00000066963
atp6v1f
ATPase H+ transporting V1 subunit F
chr3_-_46818001 6.68 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr6_-_43092175 6.57 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr12_+_33151246 6.53 ENSDART00000162681
rbfox3a
RNA binding fox-1 homolog 3a
chr18_+_2837563 6.45 ENSDART00000171495
ENSDART00000160228
fam168a
family with sequence similarity 168, member A
chr25_-_24074500 6.40 ENSDART00000040410
th
tyrosine hydroxylase
chr18_+_25003207 6.39 ENSDART00000099476
ENSDART00000132285
fam174b
family with sequence similarity 174, member B
chr5_+_15667874 6.37 ENSDART00000127015
srrm4
serine/arginine repetitive matrix 4
chr12_+_38770654 6.34 ENSDART00000155367
kif19
kinesin family member 19
chr19_+_30662529 6.28 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr4_+_17336557 6.20 ENSDART00000111650
pmch
pro-melanin-concentrating hormone
chr9_+_52411530 6.18 ENSDART00000163684
nme8
NME/NM23 family member 8
chr14_+_44545092 6.12 ENSDART00000175454
lingo2a
leucine rich repeat and Ig domain containing 2a
chr22_+_17237219 6.02 ENSDART00000090069
axdnd1
axonemal dynein light chain domain containing 1
chr22_-_24984733 5.87 ENSDART00000142147
ENSDART00000187284
dnal4b
dynein, axonemal, light chain 4b
chr20_-_7648325 5.85 ENSDART00000186541
CR848049.1

chr17_-_26604549 5.82 ENSDART00000174773
fam149b1
family with sequence similarity 149, member B1
chr18_-_14734678 5.76 ENSDART00000142462
tshz3a
teashirt zinc finger homeobox 3a
chr4_+_11458078 5.69 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr19_+_15571290 5.60 ENSDART00000131134
foxo6b
forkhead box O6 b
chr24_+_2519761 5.59 ENSDART00000106619
nrn1a
neuritin 1a
chr20_-_35841570 5.57 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr17_+_16873417 5.47 ENSDART00000146276
dio2
iodothyronine deiodinase 2
chr13_+_31648271 5.45 ENSDART00000006648
mnat1
MNAT CDK-activating kinase assembly factor 1
chr16_+_14029283 5.42 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr19_+_42219165 5.40 ENSDART00000163192
CU896644.1

chr25_-_13842618 5.39 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr14_-_7885707 5.38 ENSDART00000029981
ppp3cb
protein phosphatase 3, catalytic subunit, beta isozyme
chr2_+_3472832 5.33 ENSDART00000115278
cx47.1
connexin 47.1
chr19_-_5254699 5.32 ENSDART00000081951
stx1b
syntaxin 1B
chr23_-_32334208 5.29 ENSDART00000053472
rnf41
ring finger protein 41
chr8_+_41647539 5.27 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
si:ch211-158d24.4
chr15_+_28685892 5.24 ENSDART00000155815
ENSDART00000060244
nova2
neuro-oncological ventral antigen 2
chr25_-_29988352 5.24 ENSDART00000067059
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr21_+_33249478 5.17 ENSDART00000169972
si:ch211-151g22.1
si:ch211-151g22.1
chr22_+_3232925 5.15 ENSDART00000166754
CU929402.1

chr11_+_39672874 5.13 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr18_-_6460102 5.12 ENSDART00000137037
iqsec3b
IQ motif and Sec7 domain 3b
chr14_+_20156477 5.10 ENSDART00000123434
fmr1
fragile X mental retardation 1
chr2_+_22694382 5.07 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr17_-_26926577 5.05 ENSDART00000050202
rcan3
regulator of calcineurin 3
chr7_+_20629411 4.96 ENSDART00000173710
si:dkey-19b23.15
si:dkey-19b23.15
chr22_+_15438513 4.93 ENSDART00000010846
gpc5b
glypican 5b
chr18_-_20822045 4.91 ENSDART00000100743
cttnbp2
cortactin binding protein 2
chr16_-_41515662 4.90 ENSDART00000166201
ENSDART00000127243
siglec15l
sialic acid binding Ig-like lectin 15, like
chr7_+_32722227 4.89 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr4_-_25485404 4.88 ENSDART00000041402
pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr8_-_21268303 4.87 ENSDART00000067211
gpr37l1b
G protein-coupled receptor 37 like 1b
chr17_-_48705993 4.87 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr11_-_10798021 4.82 ENSDART00000167112
ENSDART00000179725
ENSDART00000091923
ENSDART00000185825
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr16_-_16590780 4.79 ENSDART00000059841
si:ch211-257p13.3
si:ch211-257p13.3
chr19_+_7552699 4.79 ENSDART00000180788
ENSDART00000115058
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr2_-_41620112 4.74 ENSDART00000138822
ENSDART00000004816
zgc:110158
zgc:110158
chr10_-_36592486 4.74 ENSDART00000131693
slc1a3b
solute carrier family 1 (glial high affinity glutamate transporter), member 3b
chr16_-_29480335 4.64 ENSDART00000148930
lingo4b
leucine rich repeat and Ig domain containing 4b
chr15_+_31735931 4.63 ENSDART00000185681
ENSDART00000149137
rxfp2b
relaxin/insulin-like family peptide receptor 2b
chr10_+_9595575 4.60 ENSDART00000091780
ENSDART00000184287
rc3h2
ring finger and CCCH-type domains 2
chr2_+_6181383 4.59 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr10_-_22845485 4.59 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr4_+_21129752 4.58 ENSDART00000169764
syt1a
synaptotagmin Ia
chr24_-_38079261 4.57 ENSDART00000105662
crp1
C-reactive protein 1
chr10_+_21786656 4.56 ENSDART00000185851
ENSDART00000167219
pcdh1g26
protocadherin 1 gamma 26
chr8_-_22698651 4.56 ENSDART00000181411
iqsec2a
IQ motif and Sec7 domain 2a
chr20_-_47422469 4.55 ENSDART00000021341
kif3ca
kinesin family member 3Ca
chr10_-_35542071 4.54 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr7_+_25858380 4.53 ENSDART00000148780
ENSDART00000079218
mtmr1a
myotubularin related protein 1a
chr18_-_34061477 4.53 ENSDART00000135965
plch1
phospholipase C, eta 1
chr13_+_25433774 4.49 ENSDART00000141255
si:dkey-51a16.9
si:dkey-51a16.9
chr18_+_28102620 4.47 ENSDART00000132342
kiaa1549lb
KIAA1549-like b
chr17_-_43466317 4.42 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr24_+_22759451 4.40 ENSDART00000135392
si:dkey-7n6.2
si:dkey-7n6.2
chr21_+_25643880 4.40 ENSDART00000192392
ENSDART00000145091
tmem151a
transmembrane protein 151A
chr15_+_41815703 4.38 ENSDART00000059508
pxylp1
2-phosphoxylose phosphatase 1
chr2_+_53204750 4.38 ENSDART00000163644
zgc:165603
zgc:165603
chr1_+_7517454 4.37 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr7_+_48460239 4.36 ENSDART00000052113
lingo1b
leucine rich repeat and Ig domain containing 1b
chr1_-_14234076 4.36 ENSDART00000040049
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr5_+_64368770 4.35 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr7_+_529522 4.34 ENSDART00000190811
nrxn2b
neurexin 2b
chr4_-_11163112 4.34 ENSDART00000188854
prmt8b
protein arginine methyltransferase 8b
chr15_+_28119284 4.32 ENSDART00000188366
unc119a
unc-119 homolog a (C. elegans)
chr19_-_12322356 4.31 ENSDART00000016128
ncaldb
neurocalcin delta b
chr3_-_18711288 4.26 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr23_-_35694171 4.25 ENSDART00000077539
tuba1c
tubulin, alpha 1c
chr6_+_8172227 4.25 ENSDART00000146106
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr20_-_34801181 4.25 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr3_+_33340939 4.23 ENSDART00000128786
pyya
peptide YYa
chr11_-_6188413 4.23 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr16_+_221739 4.22 ENSDART00000180243
nrsn1
neurensin 1
chr6_-_11792152 4.20 ENSDART00000183403
march7
membrane-associated ring finger (C3HC4) 7
chr9_-_48296469 4.20 ENSDART00000058255
bbs5
Bardet-Biedl syndrome 5
chr11_+_13423776 4.19 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr17_-_14726824 4.19 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr15_+_21744680 4.17 ENSDART00000016860
ppp2r1bb
protein phosphatase 2, regulatory subunit A, beta b

Network of associatons between targets according to the STRING database.

First level regulatory network of gata3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 32.9 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
7.5 30.0 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
6.9 27.5 GO:0006867 asparagine transport(GO:0006867)
6.0 24.1 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
5.9 23.5 GO:0048242 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
5.8 23.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
5.3 26.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
4.1 12.3 GO:0016264 gap junction assembly(GO:0016264)
3.4 13.6 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
3.1 9.2 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
2.7 8.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
2.6 12.8 GO:0090527 actin filament reorganization(GO:0090527)
2.4 7.1 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
2.1 6.4 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
2.0 8.1 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
1.9 13.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
1.9 5.6 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
1.8 9.2 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
1.8 10.5 GO:0003232 bulbus arteriosus development(GO:0003232)
1.6 12.7 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.5 9.0 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
1.5 48.6 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
1.3 7.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.2 7.3 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
1.2 7.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.1 29.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
1.1 8.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.1 5.6 GO:1901207 regulation of heart looping(GO:1901207)
1.1 5.5 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
1.1 3.2 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
1.0 4.2 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
1.0 3.1 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.0 9.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.0 21.6 GO:0060291 long-term synaptic potentiation(GO:0060291)
1.0 3.8 GO:0060074 synapse maturation(GO:0060074)
1.0 4.8 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.9 4.4 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.9 6.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.8 22.0 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.8 13.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.8 8.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.8 0.8 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.8 17.6 GO:0015701 bicarbonate transport(GO:0015701)
0.7 4.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.7 20.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.7 2.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.7 42.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.7 2.8 GO:0030091 protein repair(GO:0030091)
0.7 8.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.7 2.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.7 29.6 GO:0048854 brain morphogenesis(GO:0048854)
0.7 4.0 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.7 2.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.6 3.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.6 3.2 GO:0061551 trigeminal ganglion development(GO:0061551)
0.6 3.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.6 3.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.6 13.9 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.6 4.3 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.6 1.8 GO:0019695 choline metabolic process(GO:0019695)
0.6 3.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.6 2.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.6 6.8 GO:0021754 facial nucleus development(GO:0021754)
0.5 1.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 5.9 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.5 3.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 1.6 GO:0044321 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.5 3.1 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.5 3.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.5 1.0 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.5 2.4 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.5 7.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.5 11.0 GO:0007020 microtubule nucleation(GO:0007020)
0.5 3.8 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.5 1.4 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 4.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.5 2.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.4 31.8 GO:0021549 cerebellum development(GO:0021549)
0.4 11.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.4 1.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.4 1.3 GO:0015074 DNA integration(GO:0015074)
0.4 3.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.4 1.7 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.4 3.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.4 1.6 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.4 2.8 GO:0070207 protein homotrimerization(GO:0070207)
0.4 0.8 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.4 2.0 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.4 7.8 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.4 3.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.4 0.8 GO:0060688 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4 8.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 2.3 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.4 1.1 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.4 2.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 1.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.4 4.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.4 5.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 1.0 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.3 1.0 GO:0003403 optic vesicle formation(GO:0003403)
0.3 1.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 0.7 GO:0021576 hindbrain formation(GO:0021576)
0.3 15.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 1.3 GO:0046951 cellular ketone body metabolic process(GO:0046950) ketone body biosynthetic process(GO:0046951) ketone body metabolic process(GO:1902224)
0.3 3.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 2.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 4.2 GO:0007631 feeding behavior(GO:0007631)
0.3 2.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 2.2 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.3 0.6 GO:0034204 lipid translocation(GO:0034204)
0.3 1.6 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.3 14.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3 13.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 1.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.3 0.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.3 1.5 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.3 1.5 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.3 2.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.3 0.9 GO:0033335 anal fin development(GO:0033335)
0.3 10.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 2.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.3 4.6 GO:0008354 germ cell migration(GO:0008354)
0.3 1.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 3.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 9.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.3 3.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.3 1.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.1 GO:0010259 multicellular organism aging(GO:0010259)
0.3 1.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.3 1.3 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.3 4.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 2.9 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 1.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.3 19.3 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.3 0.8 GO:2001222 regulation of neuron migration(GO:2001222)
0.3 4.3 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.2 21.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.2 1.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 3.3 GO:0060325 face morphogenesis(GO:0060325)
0.2 7.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 4.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 0.7 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.2 1.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 0.9 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.2 5.0 GO:0006491 N-glycan processing(GO:0006491)
0.2 1.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 3.0 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 1.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 7.0 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.2 1.1 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.2 0.7 GO:0090085 regulation of protein deubiquitination(GO:0090085) positive regulation of protein deubiquitination(GO:1903003)
0.2 20.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 4.1 GO:0050795 regulation of behavior(GO:0050795)
0.2 3.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.9 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.2 2.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 1.9 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.2 3.4 GO:0006265 DNA topological change(GO:0006265)
0.2 0.4 GO:0071514 genetic imprinting(GO:0071514)
0.2 26.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.2 3.5 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.2 2.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 1.0 GO:0006000 fructose metabolic process(GO:0006000)
0.2 48.0 GO:0007018 microtubule-based movement(GO:0007018)
0.2 2.4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 0.8 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.2 4.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.2 0.8 GO:0007413 axonal fasciculation(GO:0007413)
0.2 1.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 7.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 0.6 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 16.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 17.4 GO:0001666 response to hypoxia(GO:0001666)
0.2 2.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 15.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.2 2.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 2.0 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 2.9 GO:0046549 retinal cone cell development(GO:0046549)
0.2 2.9 GO:0055075 potassium ion homeostasis(GO:0055075)
0.2 8.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 1.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2 1.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.2 1.6 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.2 3.1 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.2 2.9 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 0.5 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.2 2.9 GO:0015693 magnesium ion transport(GO:0015693)
0.2 5.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 2.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 8.5 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 9.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 0.5 GO:0061182 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.2 11.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 8.0 GO:0048484 enteric nervous system development(GO:0048484)
0.2 0.5 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.2 2.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 8.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 3.2 GO:0030641 regulation of pH(GO:0006885) regulation of cellular pH(GO:0030641)
0.1 9.4 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.6 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 1.3 GO:0007080 establishment of mitotic spindle orientation(GO:0000132) mitotic metaphase plate congression(GO:0007080)
0.1 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 1.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.7 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 0.9 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1 2.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 2.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 1.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 1.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 3.6 GO:0007416 synapse assembly(GO:0007416)
0.1 5.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.1 3.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 12.6 GO:0021782 glial cell development(GO:0021782)
0.1 0.8 GO:0044319 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.1 0.8 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.6 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 1.9 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 1.1 GO:0061709 reticulophagy(GO:0061709)
0.1 2.5 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 1.3 GO:0007398 ectoderm development(GO:0007398)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 7.6 GO:0007030 Golgi organization(GO:0007030)
0.1 2.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 1.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 3.4 GO:0042552 myelination(GO:0042552)
0.1 10.7 GO:0006821 chloride transport(GO:0006821)
0.1 0.5 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.3 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.6 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 2.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 17.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.1 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 2.7 GO:0032400 melanosome localization(GO:0032400)
0.1 0.7 GO:0060465 pharynx development(GO:0060465)
0.1 1.0 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 2.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 2.1 GO:0070831 basement membrane assembly(GO:0070831)
0.1 3.9 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 2.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 3.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.4 GO:0055016 hypochord development(GO:0055016)
0.1 0.7 GO:0030325 adrenal gland development(GO:0030325)
0.1 2.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.5 GO:0051030 snRNA transport(GO:0051030)
0.1 1.0 GO:0007634 optokinetic behavior(GO:0007634)
0.1 1.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.6 GO:0003315 heart rudiment morphogenesis(GO:0003314) heart rudiment formation(GO:0003315)
0.1 4.3 GO:0070509 calcium ion import(GO:0070509)
0.1 3.6 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.1 0.9 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 1.0 GO:0070828 heterochromatin organization(GO:0070828)
0.1 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289) regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.4 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.5 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.3 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.4 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 1.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.8 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 0.3 GO:0032418 lysosome localization(GO:0032418)
0.1 1.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 0.3 GO:0043111 replication fork arrest(GO:0043111)
0.1 3.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 7.0 GO:0051260 protein homooligomerization(GO:0051260)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.6 GO:0097009 energy homeostasis(GO:0097009)
0.1 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.2 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 1.6 GO:0001764 neuron migration(GO:0001764)
0.1 0.2 GO:0044107 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1 1.6 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 2.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.3 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135) positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.4 GO:0016246 RNA interference(GO:0016246)
0.1 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.1 0.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.2 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.3 GO:0007589 body fluid secretion(GO:0007589)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.5 GO:0007530 sex determination(GO:0007530)
0.0 2.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.4 GO:0061512 protein localization to cilium(GO:0061512)
0.0 5.1 GO:0007610 behavior(GO:0007610)
0.0 1.4 GO:0010906 regulation of carbohydrate metabolic process(GO:0006109) regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.5 GO:0035108 limb morphogenesis(GO:0035108)
0.0 1.6 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.9 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.3 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 1.0 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.8 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 3.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.0 GO:0006623 protein targeting to vacuole(GO:0006623) establishment of protein localization to vacuole(GO:0072666)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 6.8 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.0 5.0 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.6 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 2.7 GO:0043410 positive regulation of MAPK cascade(GO:0043410)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.0 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.2 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0035196 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918) cellular response to dsRNA(GO:0071359)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 1.5 GO:0023014 MAPK cascade(GO:0000165) signal transduction by protein phosphorylation(GO:0023014)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0035992 tendon formation(GO:0035992)
0.0 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0036353 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.0 1.9 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 1.1 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.9 GO:0009566 single fertilization(GO:0007338) fertilization(GO:0009566)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 14.5 GO:0006468 protein phosphorylation(GO:0006468)
0.0 0.4 GO:0002068 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.5 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.0 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 2.6 GO:0042325 regulation of phosphorylation(GO:0042325)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.2 GO:0097268 cytoophidium(GO:0097268)
2.7 10.8 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
2.6 10.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.7 48.5 GO:0000145 exocyst(GO:0000145)
1.5 13.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.5 8.9 GO:0005955 calcineurin complex(GO:0005955)
1.5 10.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.4 4.3 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
1.3 5.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
1.2 46.7 GO:0043679 axon terminus(GO:0043679)
1.1 22.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.1 3.2 GO:0043291 RAVE complex(GO:0043291)
0.9 4.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.8 32.6 GO:0043204 perikaryon(GO:0043204)
0.8 13.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.7 3.0 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.7 2.9 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.7 2.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 4.0 GO:0000801 central element(GO:0000801)
0.6 11.3 GO:0030667 secretory granule membrane(GO:0030667)
0.6 4.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 4.2 GO:0034464 BBSome(GO:0034464)
0.5 8.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 40.8 GO:0043025 neuronal cell body(GO:0043025)
0.5 5.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.5 1.5 GO:0032584 growth cone membrane(GO:0032584)
0.5 41.2 GO:0005871 kinesin complex(GO:0005871)
0.5 4.5 GO:0036449 microtubule minus-end(GO:0036449)
0.5 2.7 GO:0070062 extracellular exosome(GO:0070062)
0.4 14.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 4.1 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.4 1.9 GO:0071439 clathrin complex(GO:0071439)
0.4 11.2 GO:0030286 dynein complex(GO:0030286)
0.4 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.4 2.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.4 3.7 GO:0005688 U6 snRNP(GO:0005688)
0.4 2.9 GO:0072487 MSL complex(GO:0072487)
0.4 2.2 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 5.0 GO:0048179 activin receptor complex(GO:0048179)
0.3 3.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.3 13.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 9.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.3 1.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 31.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 2.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.3 0.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3 21.0 GO:0097014 ciliary plasm(GO:0097014)
0.3 9.5 GO:0030426 growth cone(GO:0030426)
0.3 17.8 GO:0031901 early endosome membrane(GO:0031901)
0.3 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.3 6.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 5.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 2.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 0.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 1.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 1.6 GO:0035517 PR-DUB complex(GO:0035517)
0.2 1.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 1.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.8 GO:0071914 prominosome(GO:0071914)
0.2 1.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 0.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 20.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.2 124.8 GO:0043005 neuron projection(GO:0043005)
0.2 3.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 6.7 GO:0014069 postsynaptic density(GO:0014069)
0.2 1.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 19.8 GO:0005925 focal adhesion(GO:0005925)
0.2 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 10.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.4 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 2.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 4.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 3.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 12.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.1 2.1 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 5.6 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.1 106.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 9.3 GO:0005681 spliceosomal complex(GO:0005681)
0.1 4.3 GO:0016342 catenin complex(GO:0016342)
0.1 1.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0001650 fibrillar center(GO:0001650)
0.1 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 59.3 GO:0005794 Golgi apparatus(GO:0005794)
0.1 0.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.7 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:0070449 elongin complex(GO:0070449)
0.1 1.1 GO:0005771 multivesicular body(GO:0005771)
0.1 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 1.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 0.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 2.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.7 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 3.8 GO:0043235 receptor complex(GO:0043235)
0.0 4.7 GO:0005874 microtubule(GO:0005874)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882) intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0060293 germ plasm(GO:0060293)
0.0 7.0 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.0 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 22.0 GO:1903136 cuprous ion binding(GO:1903136)
5.8 23.2 GO:0003883 CTP synthase activity(GO:0003883)
5.2 25.9 GO:0004127 cytidylate kinase activity(GO:0004127)
4.6 27.5 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
3.5 21.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
3.1 9.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
3.0 15.0 GO:0070412 R-SMAD binding(GO:0070412)
3.0 32.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
2.6 10.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
2.2 19.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.9 13.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.9 13.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.6 8.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
1.5 21.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.5 19.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.5 8.9 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
1.2 30.0 GO:0001540 beta-amyloid binding(GO:0001540)
1.2 7.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.1 10.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.1 9.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.1 23.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.9 48.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.9 11.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.9 7.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.9 9.1 GO:0030332 cyclin binding(GO:0030332)
0.9 4.4 GO:0043295 glutathione binding(GO:0043295)
0.8 4.2 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.8 5.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 4.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.7 15.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.7 6.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.7 3.5 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.7 42.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 2.8 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.7 6.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7 6.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.7 3.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.7 4.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.6 3.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.6 15.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.6 5.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.6 3.1 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.6 4.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.6 7.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.6 3.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.6 20.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.6 6.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.6 2.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.6 2.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.6 5.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 2.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 9.7 GO:0033691 sialic acid binding(GO:0033691)
0.5 3.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.5 22.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.5 3.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.5 11.9 GO:0030371 translation repressor activity(GO:0030371)
0.5 1.5 GO:0043621 protein self-association(GO:0043621)
0.5 11.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.5 1.4 GO:0097643 amylin receptor activity(GO:0097643)
0.5 1.4 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 1.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.4 3.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 2.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 3.0 GO:0019809 spermidine binding(GO:0019809)
0.4 3.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 5.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 1.2 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.4 5.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 1.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 1.9 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 2.6 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.4 43.2 GO:0003777 microtubule motor activity(GO:0003777)
0.4 3.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.4 1.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4 1.4 GO:0031697 adrenergic receptor binding(GO:0031690) beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.3 1.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.3 2.0 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.3 15.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 3.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 5.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 1.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 2.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.3 0.9 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.3 3.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.3 2.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 1.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.3 8.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 1.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 3.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 0.8 GO:0001729 ceramide kinase activity(GO:0001729) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 2.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 2.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 1.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.3 6.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 1.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 1.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.3 3.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 2.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 3.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 63.8 GO:0008017 microtubule binding(GO:0008017)
0.2 2.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 4.1 GO:0001671 ATPase activator activity(GO:0001671)
0.2 6.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 1.9 GO:0016530 metallochaperone activity(GO:0016530)
0.2 1.2 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 9.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 3.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 1.4 GO:0019202 amino acid kinase activity(GO:0019202)
0.2 0.9 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.2 1.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.7 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 3.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.3 GO:0008126 acetylesterase activity(GO:0008126)
0.2 8.7 GO:0051087 chaperone binding(GO:0051087)
0.2 6.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.9 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.0 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 0.6 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 1.7 GO:0004985 opioid receptor activity(GO:0004985)
0.2 5.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 3.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.2 5.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 4.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 15.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 0.7 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.2 6.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 2.7 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.2 2.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 2.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 0.8 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 2.2 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 5.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 5.3 GO:0015631 tubulin binding(GO:0015631)
0.1 2.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 3.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 5.2 GO:0019003 GDP binding(GO:0019003)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 4.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.4 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 4.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 19.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.5 GO:0031005 filamin binding(GO:0031005)
0.1 2.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 3.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.5 GO:0045503 dynein light chain binding(GO:0045503)
0.1 2.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 10.1 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 5.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 2.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 21.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 5.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.2 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.4 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 0.8 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 3.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 3.7 GO:0044325 ion channel binding(GO:0044325)
0.1 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.4 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 0.3 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 1.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.0 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.1 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.3 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.7 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 1.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.2 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.2 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.1 1.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 9.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.1 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.6 GO:0043548 insulin receptor binding(GO:0005158) phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.3 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 19.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.4 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.6 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 29.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 11.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 30.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 2.4 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0004532 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 6.5 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 5.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.0 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 2.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 23.4 PID IFNG PATHWAY IFN-gamma pathway
0.9 33.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.8 11.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.7 8.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.7 8.4 PID IGF1 PATHWAY IGF1 pathway
0.7 8.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.7 17.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.7 7.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.6 19.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 10.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 5.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 7.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 4.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 2.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 4.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 3.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 9.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 8.4 PID LKB1 PATHWAY LKB1 signaling events
0.2 1.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 3.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 5.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 1.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 6.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 6.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 4.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.4 PID BMP PATHWAY BMP receptor signaling
0.1 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.3 PID INSULIN PATHWAY Insulin Pathway
0.1 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 11.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.6 PID P73PATHWAY p73 transcription factor network
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 24.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.5 4.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.3 22.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.2 32.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
1.1 7.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
1.1 10.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.1 11.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 24.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
1.0 10.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.8 6.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.8 8.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.6 1.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 4.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 5.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.5 6.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 4.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 9.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 8.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 5.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 9.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 2.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 5.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 4.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 9.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 3.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 2.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 10.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 4.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 8.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 2.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 7.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 3.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 4.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules