ISMARA results: glis2a+glis2b

Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation

Downloads

Results for glis2a+glis2b

Z-value: 0.48

Motif logo

Transcription factors associated with glis2a+glis2b

Gene Symbol	Gene ID	Gene Info
glis2a NCBI UniProt	ENSDARG00000078388	GLIS family zinc finger 2a
glis2b NCBI UniProt	ENSDARG00000100232	GLIS family zinc finger 2b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
glis2b	dr11_v1_chr3_+_12334509_12334509	-0.20	4.9e-02	Click!
glis2a	dr11_v1_chr22_-_26558166_26558166	0.11	3.1e-01	Click!

Activity profile of glis2a+glis2b motif

Sorted Z-values of glis2a+glis2b motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_4070058 Show fit	5.75	ENSDART00000042200	aldoab NCBI UniProt Show fit	aldolase a, fructose-bisphosphate, b
chr24_+_25471196 Show fit	5.20	ENSDART00000066625	smpx NCBI UniProt Show fit	small muscle protein, X-linked
chr23_-_17470146 Show fit	2.84	ENSDART00000002398	trim101 NCBI UniProt Show fit	tripartite motif containing 101
chr23_-_45705525 Show fit	2.75	ENSDART00000148959	ednrab NCBI UniProt Show fit	endothelin receptor type Ab
chr23_+_42810055 Show fit	2.05	ENSDART00000186647	myl9a NCBI UniProt Show fit	myosin, light chain 9a, regulatory
chr7_+_18364176 Show fit	2.02	ENSDART00000171606 ENSDART00000186368	cd248a NCBI UniProt Show fit	CD248 molecule, endosialin a
chr2_-_30987538 Show fit	1.99	ENSDART00000148157	emilin2a NCBI UniProt Show fit	elastin microfibril interfacer 2a
chr9_+_20781047 Show fit	1.86	ENSDART00000139174	fam46c NCBI UniProt Show fit	family with sequence similarity 46, member C
chr17_-_20717845 Show fit	1.85	ENSDART00000150037	ank3b NCBI UniProt Show fit	ankyrin 3b
chr25_+_13191615 Show fit	1.61	ENSDART00000168849	si:ch211-147m6.2 NCBI UniProt Show fit	si:ch211-147m6.2

Showing 1 to 10 of 75 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of glis2a+glis2b

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.7	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4	2.8	GO:0003319	cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.4	1.6	GO:0060585	regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3	1.4	GO:0006116	NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0	1.2	GO:0071560	transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.2	1.1	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0	1.1	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.3	1.0	GO:0090008	hypoblast development(GO:0090008)
0.1	1.0	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2	0.7	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)

Showing 1 to 10 of 23 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	5.2	GO:0043034	costamere(GO:0043034)
0.0	3.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.2	1.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	1.3	GO:0030427	site of polarized growth(GO:0030427)
0.1	0.8	GO:0032133	chromosome passenger complex(GO:0032133)
0.2	0.6	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.4	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Showing 1 to 10 of 11 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.7	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.4	2.8	GO:0004962	endothelin receptor activity(GO:0004962)
0.7	2.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.4	1.6	GO:0031708	endothelin B receptor binding(GO:0031708)
0.3	1.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	1.1	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.1	1.0	GO:0038064	protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1	1.0	GO:0070697	activin receptor binding(GO:0070697)
0.0	0.7	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.6	GO:0043015	gamma-tubulin binding(GO:0043015)

Showing 1 to 10 of 18 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	PID ENDOTHELIN PATHWAY	Endothelins
0.1	1.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.0	PID GLYPICAN 1PATHWAY	Glypican 1 network

Showing 1 to 3 of 3 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	1.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	0.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.6	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling

Showing 1 to 7 of 7 entries

Results for glis2a+glis2b

Z-value: 0.48

Motif logo

Transcription factors associated with glis2a+glis2b

Activity-expression correlation:

Activity profile of glis2a+glis2b motif

Sorted Z-values of glis2a+glis2b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of glis2a+glis2b

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: