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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for grhl1
Z-value: 4.15
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Transcription factors associated with grhl1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| grhl1 | dr11_v1_chr17_-_32413147_32413147 | 0.86 | 4.0e-28 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_12360409 Show fit | 87.74 |
ENSDART00000164596
|
transmembrane protease, serine 13a |
|
| chr9_-_30264415 Show fit | 86.84 |
ENSDART00000060150
|
MID1 interacting protein 1a |
|
| chr15_+_42560354 Show fit | 79.94 |
ENSDART00000059484
|
zgc:110333 |
|
| chr16_-_9675982 Show fit | 75.55 |
ENSDART00000113724
|
mal, T cell differentiation protein 2 (gene/pseudogene) |
|
| chr12_-_28794957 Show fit | 74.02 |
ENSDART00000020667
|
oxysterol binding protein-like 7 |
|
| chr21_+_11244068 Show fit | 71.31 |
ENSDART00000163432
|
AT-rich interaction domain 6 |
|
| chr7_+_22657566 Show fit | 69.46 |
ENSDART00000141048
|
plac8 onzin related protein 5 |
|
| chr24_+_38671054 Show fit | 65.02 |
ENSDART00000154214
|
si:ch73-70c5.1 |
|
| chr8_-_24252933 Show fit | 59.77 |
ENSDART00000057624
|
zgc:110353 |
|
| chr10_-_36793412 Show fit | 59.37 |
ENSDART00000185966
|
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of grhl1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 143.8 | GO:0006508 | proteolysis(GO:0006508) |
| 0.1 | 95.4 | GO:0005975 | carbohydrate metabolic process(GO:0005975) |
| 1.7 | 87.9 | GO:0036269 | swimming behavior(GO:0036269) |
| 1.5 | 86.8 | GO:0046890 | regulation of lipid biosynthetic process(GO:0046890) |
| 15.1 | 75.5 | GO:0045056 | transcytosis(GO:0045056) |
| 0.1 | 68.2 | GO:0015031 | protein transport(GO:0015031) |
| 0.3 | 66.5 | GO:0006869 | lipid transport(GO:0006869) |
| 3.1 | 59.4 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 1.3 | 57.5 | GO:0045103 | intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 56.9 | GO:0006357 | regulation of transcription from RNA polymerase II promoter(GO:0006357) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 369.5 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 171.3 | GO:0005634 | nucleus(GO:0005634) |
| 0.1 | 115.7 | GO:0005576 | extracellular region(GO:0005576) |
| 0.2 | 93.0 | GO:0009986 | cell surface(GO:0009986) |
| 0.7 | 75.5 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 4.9 | 74.0 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 69.9 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.2 | 59.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 59.4 | GO:0005874 | microtubule(GO:0005874) |
| 0.3 | 58.4 | GO:0098791 | Golgi subcompartment(GO:0098791) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 165.8 | GO:0000976 | transcription regulatory region sequence-specific DNA binding(GO:0000976) |
| 0.5 | 95.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 3.1 | 87.9 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.7 | 86.1 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 8.6 | 77.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 5.0 | 75.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 2.7 | 74.0 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 65.6 | GO:0008270 | zinc ion binding(GO:0008270) |
| 5.9 | 59.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 9.6 | 57.5 | GO:0019215 | intermediate filament binding(GO:0019215) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.4 | 13.8 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 2.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.3 | 87.9 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 2.8 | 45.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.6 | 29.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 2.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 2.2 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |