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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for gsc

Z-value: 0.57

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Transcription factors associated with gsc

Gene Symbol Gene ID Gene Info
gsc
ENSDARG00000059073 goosecoid
gsc
ENSDARG00000111184 goosecoid
gsc
ENSDARG00000115937 goosecoid

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gscdr11_v1_chr17_-_19345521_193455210.381.6e-04Click!

Activity profile of gsc motif

Sorted Z-values of gsc motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_36378494 6.35 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr3_-_32170850 5.35 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr19_+_24882845 4.93 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr22_+_34701848 4.75 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr2_-_30784198 4.32 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr6_+_48618512 3.98 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr18_+_49969568 3.66 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr22_+_5103349 3.43 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr3_+_34919810 3.07 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr16_+_32059785 2.95 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr17_-_16965809 2.94 ENSDART00000153697
nrxn3a
neurexin 3a
chr4_-_7212875 2.60 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr7_-_57933736 2.58 ENSDART00000142580
ank2b
ankyrin 2b, neuronal
chr10_-_22845485 2.54 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr3_+_26144765 2.50 ENSDART00000146267
ENSDART00000043932
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr20_-_18736281 2.48 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr23_-_5759242 2.45 ENSDART00000055087
phlda3
pleckstrin homology-like domain, family A, member 3
chr6_-_35401282 2.37 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chrM_+_12897 2.36 ENSDART00000093622
mt-nd5
NADH dehydrogenase 5, mitochondrial
chr20_-_25436389 2.36 ENSDART00000153266
itsn2a
intersectin 2a
chr5_-_28625515 2.36 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tnc
tenascin C
chr7_-_49594995 2.35 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr14_+_34966598 2.33 ENSDART00000004550
rnf145a
ring finger protein 145a
chr14_-_29799993 2.32 ENSDART00000133775
ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr19_+_2631565 2.32 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr1_-_45177373 2.19 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr17_+_35097024 2.14 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr23_+_13814978 2.14 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr5_+_43072951 2.12 ENSDART00000193905
ENSDART00000026020
wdr54
WD repeat domain 54
chr18_-_36135799 2.09 ENSDART00000059344
b3gat1a
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr6_-_345503 2.02 ENSDART00000168901
pde6ha
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr24_-_24271629 1.85 ENSDART00000135060
rps6ka3b
ribosomal protein S6 kinase, polypeptide 3b
chr25_+_16079913 1.84 ENSDART00000146350
far1
fatty acyl CoA reductase 1
chr8_-_25814263 1.84 ENSDART00000143397
taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_-_10705916 1.84 ENSDART00000164038
FO704786.1

chr18_+_7639401 1.81 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr17_-_32426392 1.79 ENSDART00000148455
ENSDART00000149885
ENSDART00000179314
grhl1
grainyhead-like transcription factor 1
chr21_-_35419486 1.75 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr10_-_22249444 1.75 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr16_+_42829735 1.73 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr1_-_45146834 1.71 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr25_+_16080181 1.70 ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr11_-_29563437 1.66 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr23_-_23256726 1.64 ENSDART00000131353
si:dkey-98j1.5
si:dkey-98j1.5
chr16_+_42830152 1.63 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr24_-_38079261 1.61 ENSDART00000105662
crp1
C-reactive protein 1
chr10_-_25628555 1.60 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr3_-_28828242 1.60 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr12_+_41991635 1.57 ENSDART00000186161
ENSDART00000192510
TCERG1L
transcription elongation regulator 1 like
chr17_-_20979077 1.56 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr23_+_6232895 1.51 ENSDART00000139795
syt2a
synaptotagmin IIa
chr10_-_37075361 1.50 ENSDART00000132023
myo18aa
myosin XVIIIAa
chr9_+_32073606 1.49 ENSDART00000184170
ENSDART00000180355
ENSDART00000110204
ENSDART00000123278
pikfyve
phosphoinositide kinase, FYVE finger containing
chr11_+_36180349 1.49 ENSDART00000012940
grm2b
glutamate receptor, metabotropic 2b
chr21_+_33187992 1.47 ENSDART00000162745
ENSDART00000188388
BX072577.1

chr11_+_29671661 1.45 ENSDART00000024318
ENSDART00000165024
rnf207a
ring finger protein 207a
chr6_-_59381391 1.44 ENSDART00000157066
ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr7_+_52887701 1.43 ENSDART00000109973
tp53bp1
tumor protein p53 binding protein, 1
chr13_-_31622195 1.41 ENSDART00000057432
six1a
SIX homeobox 1a
chr16_+_25095483 1.39 ENSDART00000155032
si:ch211-261d7.3
si:ch211-261d7.3
chr19_-_41069573 1.38 ENSDART00000111982
ENSDART00000193142
sgce
sarcoglycan, epsilon
chr2_-_31664615 1.35 ENSDART00000190546
ENSDART00000111810
si:ch211-106h4.9
si:ch211-106h4.9
chr5_+_59494079 1.33 ENSDART00000148727
gtf2ird1
GTF2I repeat domain containing 1
chr5_+_1278092 1.32 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr9_+_32978302 1.32 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr12_+_47044707 1.32 ENSDART00000186506
zranb1a
zinc finger, RAN-binding domain containing 1a
chr13_-_39947335 1.28 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr19_-_42291355 1.26 ENSDART00000150919
ENSDART00000151034
si:ch211-191i18.2
si:ch211-191i18.2
chr1_+_16573982 1.25 ENSDART00000166317
mtus1b
microtubule associated tumor suppressor 1b
chr17_-_15657029 1.21 ENSDART00000153925
fut9a
fucosyltransferase 9a
chr13_-_36525982 1.17 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr7_-_50517023 1.17 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr5_-_14390445 1.15 ENSDART00000026120
ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr19_-_32518556 1.14 ENSDART00000103410
zbtb8b
zinc finger and BTB domain containing 8B
chr10_+_29260096 1.14 ENSDART00000088973
sytl2a
synaptotagmin-like 2a
chr18_-_17531483 1.14 ENSDART00000061000
bbs2
Bardet-Biedl syndrome 2
chr5_+_24287927 1.13 ENSDART00000143563
zdhhc23a
zinc finger, DHHC-type containing 23a
chr9_-_48296469 1.09 ENSDART00000058255
bbs5
Bardet-Biedl syndrome 5
chr20_-_9963713 1.07 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr10_-_20453995 1.06 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
si:ch211-113d22.2
chr10_-_41400049 1.04 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr19_+_2275019 1.04 ENSDART00000136138
itgb8
integrin, beta 8
chr5_+_31791001 1.03 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr19_+_42693855 1.03 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr15_-_26887028 0.95 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr12_+_35587971 0.94 ENSDART00000166072
ENSDART00000181861
ENSDART00000158043
chmp6b
charged multivesicular body protein 6b
chr2_-_32387441 0.94 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr20_+_37866686 0.93 ENSDART00000036546
vash2
vasohibin 2
chr5_+_60518611 0.93 ENSDART00000130565
ENSDART00000186310
tmem132e
transmembrane protein 132E
chr20_+_37866861 0.92 ENSDART00000153220
vash2
vasohibin 2
chr12_-_19119176 0.91 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr24_-_6501211 0.90 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
gpr158a
G protein-coupled receptor 158a
chr3_+_34220194 0.90 ENSDART00000145859
slc25a23b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr16_-_20932896 0.89 ENSDART00000180646
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr1_+_38362412 0.89 ENSDART00000075086
cep44
centrosomal protein 44
chr17_-_33414781 0.86 ENSDART00000142203
ENSDART00000034638
ccdc28a
coiled-coil domain containing 28A
chr7_-_18656069 0.85 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr2_-_52365251 0.85 ENSDART00000097716
tle2c
transducin like enhancer of split 2c
chr17_-_50010121 0.84 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr10_-_7988396 0.84 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr23_-_21797517 0.83 ENSDART00000110041
lrrc38a
leucine rich repeat containing 38a
chr13_+_39182099 0.82 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr7_-_12821277 0.82 ENSDART00000091584
zgc:158785
zgc:158785
chr3_-_16227490 0.79 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr14_+_5861435 0.79 ENSDART00000041279
ENSDART00000147341
tubb4b
tubulin, beta 4B class IVb
chr2_+_24199073 0.79 ENSDART00000144110
map4l
microtubule associated protein 4 like
chr3_-_10970502 0.78 ENSDART00000127500
CR382337.1

chr14_+_44545092 0.77 ENSDART00000175454
lingo2a
leucine rich repeat and Ig domain containing 2a
chr4_+_14926948 0.77 ENSDART00000019647
psmc2
proteasome 26S subunit, ATPase 2
chr3_+_41922114 0.76 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_4797512 0.76 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr2_-_57264262 0.75 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
mbd3a
methyl-CpG binding domain protein 3a
chr18_-_1228688 0.73 ENSDART00000064403
nptnb
neuroplastin b
chr13_+_3954540 0.73 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr23_+_17509794 0.72 ENSDART00000148457
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr21_-_20945658 0.72 ENSDART00000079701
rnf180
ring finger protein 180
chr1_+_47091468 0.70 ENSDART00000036783
cryzl1
crystallin, zeta (quinone reductase)-like 1
chr23_-_28294763 0.70 ENSDART00000139537
znf385a
zinc finger protein 385A
chr12_-_10038870 0.70 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr7_-_20103384 0.70 ENSDART00000052902
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr2_-_42071558 0.70 ENSDART00000142792
cspp1b
centrosome and spindle pole associated protein 1b
chr21_+_15756549 0.69 ENSDART00000026903
ptpra
protein tyrosine phosphatase, receptor type, A
chr15_-_15469079 0.69 ENSDART00000132637
ENSDART00000004220
rab34a
RAB34, member RAS oncogene family a
chr10_+_22134606 0.68 ENSDART00000155228
si:dkey-4c2.11
si:dkey-4c2.11
chr20_+_32473584 0.67 ENSDART00000192449
ostm1
osteopetrosis associated transmembrane protein 1
chr18_-_6943577 0.65 ENSDART00000132399
si:dkey-266m15.6
si:dkey-266m15.6
chr4_+_33012407 0.62 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr2_-_1569250 0.59 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr15_-_15468326 0.58 ENSDART00000161192
rab34a
RAB34, member RAS oncogene family a
chr16_+_29555801 0.58 ENSDART00000169425
ensab
endosulfine alpha b
chr15_-_23508214 0.58 ENSDART00000115051
abcg4b
ATP-binding cassette, sub-family G (WHITE), member 4b
chr12_+_7865470 0.57 ENSDART00000161683
BX548028.1

chr2_+_36828243 0.57 ENSDART00000135754
ENSDART00000140474
nrd1a
nardilysin a (N-arginine dibasic convertase)
chr3_+_26322596 0.56 ENSDART00000172700
si:ch211-156b7.5
si:ch211-156b7.5
chr15_+_45640906 0.56 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr9_+_10770880 0.56 ENSDART00000003543
ENSDART00000178966
gmppaa
GDP-mannose pyrophosphorylase Aa
chr12_+_5530247 0.56 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr19_+_35799384 0.55 ENSDART00000076023
angpt2b
angiopoietin 2b
chr14_-_46395408 0.54 ENSDART00000147537
bbs7
Bardet-Biedl syndrome 7
chr24_+_37825634 0.52 ENSDART00000129889
ift140
intraflagellar transport 140 homolog (Chlamydomonas)
chr15_+_45591669 0.51 ENSDART00000157459
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr19_+_18799319 0.51 ENSDART00000171843
ddah2
dimethylarginine dimethylaminohydrolase 2
chr2_+_28995776 0.50 ENSDART00000138733
cdh12a
cadherin 12, type 2a (N-cadherin 2)
chr1_+_41690402 0.50 ENSDART00000177298
fbxo41
F-box protein 41
chr2_-_5356686 0.50 ENSDART00000124290
MFN1
mitofusin 1
chr10_+_32104305 0.49 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr4_-_14926637 0.48 ENSDART00000110199
prdm4
PR domain containing 4
chr24_-_24060632 0.48 ENSDART00000090514
abcc13
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr5_+_28973264 0.48 ENSDART00000005638
stxbp1b
syntaxin binding protein 1b
chr3_-_16227683 0.48 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr10_+_13279079 0.45 ENSDART00000135082
tmem267
transmembrane protein 267
chr24_-_1303553 0.45 ENSDART00000190984
nrp1a
neuropilin 1a
chr3_+_52475058 0.44 ENSDART00000035867
si:ch211-241f5.3
si:ch211-241f5.3
chr14_+_7699443 0.43 ENSDART00000123139
brd8
bromodomain containing 8
chr2_+_4146299 0.42 ENSDART00000173418
mib1
mindbomb E3 ubiquitin protein ligase 1
chr25_-_32381642 0.42 ENSDART00000133872
ENSDART00000006124
cops2
COP9 signalosome subunit 2
chr8_+_14381272 0.41 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr8_+_18615938 0.41 ENSDART00000089161
si:ch211-232d19.4
si:ch211-232d19.4
chr19_-_42238003 0.40 ENSDART00000151022
si:ch211-191i18.4
si:ch211-191i18.4
chr5_+_28972935 0.40 ENSDART00000193274
stxbp1b
syntaxin binding protein 1b
chr2_-_30055432 0.40 ENSDART00000056747
shhb
sonic hedgehog b
chr19_+_3140313 0.39 ENSDART00000125504
zgc:86598
zgc:86598
chr23_-_9855627 0.39 ENSDART00000180159
prkcbp1l
protein kinase C binding protein 1, like
chr25_-_32751982 0.37 ENSDART00000012862
isl2a
ISL LIM homeobox 2a
chr8_+_4337312 0.37 ENSDART00000182228
myl2b
myosin, light chain 2b, regulatory, cardiac, slow
chr18_+_45114392 0.36 ENSDART00000172328
large2
LARGE xylosyl- and glucuronyltransferase 2
chr22_+_35205546 0.35 ENSDART00000189203
tsc22d2
TSC22 domain family 2
chr22_-_22147375 0.35 ENSDART00000149304
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr7_-_21905851 0.33 ENSDART00000111066
ENSDART00000020288
epoa
erythropoietin a
chr15_+_42995381 0.32 ENSDART00000152222
acsl3a
acyl-CoA synthetase long chain family member 3a
chr4_-_760560 0.32 ENSDART00000103601
agbl5
ATP/GTP binding protein-like 5
chr1_+_16574312 0.30 ENSDART00000187067
mtus1b
microtubule associated tumor suppressor 1b
chr25_+_7299488 0.29 ENSDART00000184836
hmg20a
high mobility group 20A
chr5_+_26199537 0.29 ENSDART00000144303
zgc:86811
zgc:86811
chr7_+_66884291 0.27 ENSDART00000187499
sbf2
SET binding factor 2
chr7_+_30970045 0.26 ENSDART00000155974
tjp1a
tight junction protein 1a
chr5_+_67371650 0.25 ENSDART00000142156
sebox
SEBOX homeobox
chr22_-_26100282 0.24 ENSDART00000166075
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr2_-_9818640 0.22 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr1_-_9109699 0.21 ENSDART00000147833
vap
vascular associated protein
chr19_+_4061699 0.21 ENSDART00000158309
ENSDART00000166512
btr25
btr26
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr2_+_36828746 0.20 ENSDART00000186638
nrd1a
nardilysin a (N-arginine dibasic convertase)
chr1_-_17650223 0.20 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr23_-_18981595 0.20 ENSDART00000147617
bcl2l1
bcl2-like 1
chr20_+_34671386 0.20 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr9_-_14084743 0.19 ENSDART00000056105
fer1l6
fer-1-like family member 6
chr6_-_19270484 0.19 ENSDART00000186894
ENSDART00000188709
zgc:174863
zgc:174863
chr18_+_21951551 0.19 ENSDART00000146261
ranbp10
RAN binding protein 10
chr7_+_66884570 0.17 ENSDART00000082664
sbf2
SET binding factor 2
chr20_-_14680897 0.17 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr3_+_23703704 0.16 ENSDART00000024256
hoxb6a
homeobox B6a
chr11_+_15613218 0.16 ENSDART00000066033
gdf11
growth differentiation factor 11
chr17_-_14559576 0.15 ENSDART00000162452
daam1a
dishevelled associated activator of morphogenesis 1a
chr24_+_37533728 0.14 ENSDART00000061203
rhot2
ras homolog family member T2
chr5_-_26199505 0.14 ENSDART00000132950
rad17
RAD17 checkpoint clamp loader component
chr1_-_7894255 0.14 ENSDART00000167126
ENSDART00000145460
radil
Ras association and DIL domains
chr19_-_42238440 0.13 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr6_+_41186320 0.13 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr17_+_24632440 0.12 ENSDART00000157092
map4k3b
mitogen-activated protein kinase kinase kinase kinase 3b
chr23_-_36313431 0.11 ENSDART00000125860
nfe2
nuclear factor, erythroid 2

Network of associatons between targets according to the STRING database.

First level regulatory network of gsc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.8 5.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 2.5 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.6 2.4 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.5 2.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.4 1.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 1.4 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.3 2.0 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.3 3.4 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 1.8 GO:0003334 keratinocyte development(GO:0003334)
0.3 0.5 GO:0045428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.3 1.1 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.3 1.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 2.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 2.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 0.8 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.7 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.2 2.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 1.7 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.2 1.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 1.7 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.8 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0055016 hypochord development(GO:0055016)
0.1 1.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 3.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.5 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 3.9 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 0.8 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 2.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 1.2 GO:0036065 fucosylation(GO:0036065)
0.1 0.6 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.3 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 1.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.2 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.1 4.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 1.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 3.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.7 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.4 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 1.0 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.7 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.9 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.0 GO:0007099 centriole replication(GO:0007099)
0.0 1.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 6.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 2.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 1.6 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.7 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.6 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.8 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.6 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.8 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.2 GO:0030878 thyroid gland development(GO:0030878)
0.0 1.5 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 3.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 2.4 GO:0016197 endosomal transport(GO:0016197)
0.0 3.1 GO:0001525 angiogenesis(GO:0001525)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0031673 H zone(GO:0031673)
0.5 5.7 GO:0044295 axonal growth cone(GO:0044295)
0.3 2.8 GO:0034464 BBSome(GO:0034464)
0.3 4.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 1.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 2.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.6 GO:0030315 T-tubule(GO:0030315)
0.2 3.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 7.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 1.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 2.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.1 GO:0005813 centrosome(GO:0005813)
0.0 0.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 2.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 3.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 1.4 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.3 7.4 GO:0005523 tropomyosin binding(GO:0005523)
0.3 3.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 0.9 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 2.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 2.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 2.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 4.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 3.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.7 GO:0005035 death receptor activity(GO:0005035)
0.1 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 3.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 4.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 6.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.0 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 4.5 GO:0003924 GTPase activity(GO:0003924)
0.0 3.5 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.6 PID ATM PATHWAY ATM pathway
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 5.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus