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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for gsx2+pnx

Z-value: 1.17

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Transcription factors associated with gsx2+pnx

Gene Symbol Gene ID Gene Info
pnx
ENSDARG00000025899 posterior neuron-specific homeobox
gsx2
ENSDARG00000043322 GS homeobox 2
gsx2
ENSDARG00000116417 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gsx2dr11_v1_chr20_-_22484621_22484621-0.251.5e-02Click!
pnxdr11_v1_chr10_+_2799285_27992850.056.1e-01Click!

Activity profile of gsx2+pnx motif

Sorted Z-values of gsx2+pnx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_51597677 17.50 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr20_+_26966725 16.33 ENSDART00000029781
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr25_+_29160102 15.45 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr2_+_55982300 14.86 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr23_+_20110086 13.77 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr25_+_31267268 13.64 ENSDART00000181239
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr13_+_22479988 12.24 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr25_+_35019693 11.10 ENSDART00000046218
flnca
filamin C, gamma a (actin binding protein 280)
chr25_+_31277415 10.13 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr15_-_12011390 9.82 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr6_-_54815886 9.07 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr19_-_25119443 9.00 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr9_-_22834860 8.55 ENSDART00000146486
neb
nebulin
chr12_-_33357655 8.25 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr12_+_22580579 8.14 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr22_+_16308450 8.12 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr19_+_2631565 8.08 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr25_+_5035343 8.04 ENSDART00000011751
parvb
parvin, beta
chr19_-_2861444 7.97 ENSDART00000169053
clec3bb
C-type lectin domain family 3, member Bb
chr17_-_37395460 7.78 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr1_-_14332283 6.79 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr23_-_31512496 6.29 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr16_-_42933332 6.27 ENSDART00000057305
thbs3a
thrombospondin 3a
chr7_-_71758307 6.25 ENSDART00000161067
ENSDART00000165253
myom1b
myomesin 1b
chr22_+_19407531 6.17 ENSDART00000141060
si:dkey-78l4.2
si:dkey-78l4.2
chr15_-_12011202 6.10 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
si:dkey-202l22.6
chr9_-_6372535 5.95 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr25_+_31276842 5.95 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr24_+_3307857 5.89 ENSDART00000106527
gyg1b
glycogenin 1b
chr6_-_40581376 5.58 ENSDART00000185412
tspo
translocator protein
chr22_-_30770751 5.51 ENSDART00000172115
AL831726.2

chr4_+_76575585 5.47 ENSDART00000131588
ms4a17a.11
membrane-spanning 4-domains, subfamily A, member 17A.11
chr2_-_2957970 5.46 ENSDART00000162505
si:ch1073-82l19.1
si:ch1073-82l19.1
chr24_+_19415124 5.37 ENSDART00000186931
sulf1
sulfatase 1
chr21_-_5205617 5.29 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr3_+_59784632 5.25 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr6_+_6924637 4.95 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr4_+_9011448 4.93 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr7_-_51368681 4.92 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr8_+_22516728 4.88 ENSDART00000146013
si:ch211-261n11.3
si:ch211-261n11.3
chr18_+_48423973 4.86 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr4_+_73085993 4.76 ENSDART00000165749
si:ch73-170d6.2
si:ch73-170d6.2
chr3_-_15734358 4.65 ENSDART00000137325
mvp
major vault protein
chr9_-_813511 4.59 ENSDART00000082368
marco
macrophage receptor with collagenous structure
chr11_-_2131280 4.54 ENSDART00000008409
calcoco1b
calcium binding and coiled-coil domain 1b
chr20_-_35578435 4.51 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr15_-_36533322 4.50 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr4_+_22480169 4.42 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr19_-_7690975 4.39 ENSDART00000151384
si:dkey-204a24.10
si:dkey-204a24.10
chr6_-_7720332 4.38 ENSDART00000135945
rpsa
ribosomal protein SA
chr3_-_15734530 4.35 ENSDART00000141142
mvp
major vault protein
chr18_-_46256560 4.35 ENSDART00000171375
si:dkey-244a7.1
si:dkey-244a7.1
chr18_-_46258612 4.25 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr21_+_18997511 4.18 ENSDART00000145591
rpl17
ribosomal protein L17
chr7_-_48667056 4.01 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr14_+_924876 3.98 ENSDART00000183908
myoz3a
myozenin 3a
chr19_-_38611814 3.89 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr20_-_1378514 3.87 ENSDART00000181830
scara5
scavenger receptor class A, member 5 (putative)
chr17_+_16046314 3.81 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr16_+_13818500 3.81 ENSDART00000135245
flcn
folliculin
chr4_+_77943184 3.81 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr9_-_14683574 3.80 ENSDART00000144022
pard3bb
par-3 family cell polarity regulator beta b
chr11_+_44135351 3.76 ENSDART00000182914
FO704721.1

chr5_+_40485503 3.72 ENSDART00000051055
ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr12_-_33354409 3.70 ENSDART00000178515
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr15_+_934660 3.66 ENSDART00000154248
si:dkey-77f5.10
si:dkey-77f5.10
chr10_+_32104305 3.64 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr20_-_9462433 3.59 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr23_-_969844 3.54 ENSDART00000127037
cdh26.2
cadherin 26, tandem duplicate 2
chr12_+_20352400 3.54 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr20_-_14925281 3.49 ENSDART00000152641
dnm3a
dynamin 3a
chr18_-_48547564 3.47 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr8_-_31107537 3.45 ENSDART00000098925
vgll4l
vestigial like 4 like
chr22_+_19218733 3.38 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
si:dkey-21e2.7
chr24_+_37640626 3.34 ENSDART00000008047
wdr24
WD repeat domain 24
chr19_-_5669122 3.33 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr21_+_43328685 3.33 ENSDART00000109620
ENSDART00000139668
sept8a
septin 8a
chr6_-_19271210 3.30 ENSDART00000163628
ENSDART00000159124
zgc:174863
zgc:174863
chr13_+_35637048 3.30 ENSDART00000085037
thbs2a
thrombospondin 2a
chr13_-_35808904 3.29 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr15_-_4528326 3.27 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr2_+_30368800 3.09 ENSDART00000179564
pi15b
peptidase inhibitor 15b
chr3_+_18398876 3.07 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr12_-_4532066 2.97 ENSDART00000092687
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr13_-_36798204 2.96 ENSDART00000012357
sav1
salvador family WW domain containing protein 1
chr3_-_34084387 2.96 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr18_+_23408073 2.95 ENSDART00000136489
mctp2a
multiple C2 domains, transmembrane 2a
chr11_+_38280454 2.95 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr6_+_50381347 2.91 ENSDART00000055504
cyc1
cytochrome c-1
chr1_-_513762 2.91 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr24_+_22485710 2.85 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr3_+_27798094 2.85 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr23_+_44374041 2.83 ENSDART00000136056
ephb4b
eph receptor B4b
chr24_+_22731228 2.80 ENSDART00000146733
si:dkey-225k4.1
si:dkey-225k4.1
chr7_-_30174882 2.79 ENSDART00000110409
frmd5
FERM domain containing 5
chr25_-_12937727 2.77 ENSDART00000172643
ccl39.6
chemokine (C-C motif) ligand 39, duplicate 6
chr13_+_35637875 2.63 ENSDART00000180657
thbs2a
thrombospondin 2a
chr2_-_37140423 2.62 ENSDART00000144220
tspan37
tetraspanin 37
chr21_-_22827548 2.62 ENSDART00000079161
angptl5
angiopoietin-like 5
chr2_+_30369116 2.56 ENSDART00000142137
pi15b
peptidase inhibitor 15b
chr1_-_58505626 2.56 ENSDART00000171304
si:ch73-236c18.8
si:ch73-236c18.8
chr25_+_28825657 2.55 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr16_-_51288178 2.49 ENSDART00000079864
zgc:173729
zgc:173729
chr19_+_43780970 2.46 ENSDART00000063870
rpl11
ribosomal protein L11
chr1_-_51719110 2.42 ENSDART00000190574
rnaseh2a
ribonuclease H2, subunit A
chr20_+_25225112 2.41 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr17_+_44697604 2.38 ENSDART00000156625
pgfb
placental growth factor b
chr16_+_13818743 2.37 ENSDART00000090191
flcn
folliculin
chr24_-_37640705 2.35 ENSDART00000066583
zgc:112496
zgc:112496
chr6_+_41191482 2.32 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr4_+_58576146 2.30 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr24_+_6107901 2.29 ENSDART00000156419
si:ch211-37e10.2
si:ch211-37e10.2
chr3_-_23643751 2.26 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr5_-_61624693 2.23 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr16_-_54498109 2.22 ENSDART00000083713
clk2b
CDC-like kinase 2b
chr9_-_5263947 2.18 ENSDART00000088342
cytip
cytohesin 1 interacting protein
chr16_-_51271962 2.18 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr3_+_32112004 2.16 ENSDART00000105272
zgc:173593
zgc:173593
chr6_-_33878665 2.16 ENSDART00000129916
tmem69
transmembrane protein 69
chr4_+_74929427 2.16 ENSDART00000174082
nup50
nucleoporin 50
chr7_+_38936132 2.15 ENSDART00000173945
creb3l1
cAMP responsive element binding protein 3-like 1
chr25_-_13490744 2.15 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr20_-_14924858 2.13 ENSDART00000047039
dnm3a
dynamin 3a
chr15_+_31701716 2.10 ENSDART00000113370
b3glcta
beta 3-glucosyltransferase a
chr9_+_30421489 2.10 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr8_-_15129573 2.08 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr21_-_26490186 2.06 ENSDART00000009889
zgc:110540
zgc:110540
chr17_+_12865746 2.06 ENSDART00000157083
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr9_+_38372216 2.00 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr20_-_29864390 1.99 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr1_-_19502322 1.99 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr10_-_42297889 1.96 ENSDART00000099262
tcf7l1a
transcription factor 7 like 1a
chr8_+_20776654 1.96 ENSDART00000135850
nfic
nuclear factor I/C
chr21_+_1381276 1.94 ENSDART00000192907
TCF4
transcription factor 4
chr1_-_59287410 1.93 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr17_+_43908428 1.91 ENSDART00000180332
msh4
mutS homolog 4
chr1_-_57629639 1.89 ENSDART00000158984
zmp:0000001289
zmp:0000001289
chr19_-_3724605 1.88 ENSDART00000123757
smim13
small integral membrane protein 13
chr4_+_306036 1.87 ENSDART00000103659
msgn1
mesogenin 1
chr6_+_24420523 1.86 ENSDART00000185461
tgfbr3
transforming growth factor, beta receptor III
chr10_-_15963903 1.84 ENSDART00000142357
si:dkey-3h23.3
si:dkey-3h23.3
chr2_+_10007113 1.84 ENSDART00000155213
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr3_-_18744511 1.83 ENSDART00000145539
zgc:113333
zgc:113333
chr1_+_513986 1.83 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr1_+_58116900 1.80 ENSDART00000160436
si:ch211-15j1.5
si:ch211-15j1.5
chr15_+_5088210 1.79 ENSDART00000183423
mxf
myxovirus (influenza virus) resistance F
chr1_-_58963395 1.76 ENSDART00000130415
CABZ01115881.1

chr19_+_3826782 1.76 ENSDART00000169222
oscp1a
organic solute carrier partner 1a
chr11_+_43043171 1.75 ENSDART00000180344
CABZ01092982.1

chr14_-_4145594 1.74 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr5_+_69747417 1.73 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr3_-_50443607 1.71 ENSDART00000074036
rcvrna
recoverin a
chr21_-_45077429 1.71 ENSDART00000187268
ENSDART00000191003
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr9_+_43799829 1.70 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr24_-_36680261 1.69 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr12_-_46112892 1.68 ENSDART00000187128
ENSDART00000114268
zgc:153932
zgc:153932
chr14_-_14640401 1.66 ENSDART00000168027
ENSDART00000167521
znf185
zinc finger protein 185 with LIM domain
chr23_+_4741543 1.64 ENSDART00000144761
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
chr14_+_5385855 1.58 ENSDART00000031508
lbx2
ladybird homeobox 2
chr15_+_5277761 1.56 ENSDART00000153954
si:ch1073-166e24.4
si:ch1073-166e24.4
chr2_+_1714640 1.56 ENSDART00000086761
ENSDART00000111613
adgrl2b.1
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr16_-_31754102 1.53 ENSDART00000185043
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr8_+_52619365 1.52 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr8_+_29986265 1.52 ENSDART00000148258
ptch1
patched 1
chr9_+_711638 1.51 ENSDART00000191964
ybey
ybeY metallopeptidase
chr19_+_1831911 1.50 ENSDART00000166653
ptk2aa
protein tyrosine kinase 2aa
chr21_-_45076778 1.49 ENSDART00000181525
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr8_-_53044300 1.48 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr15_+_41027466 1.46 ENSDART00000075940
mtnr1ba
melatonin receptor type 1Ba
chr12_+_3571770 1.46 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr19_-_657439 1.44 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr24_-_6078222 1.42 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr6_+_52927651 1.41 ENSDART00000141094
si:dkeyp-3f10.11
si:dkeyp-3f10.11
chr14_-_14643190 1.41 ENSDART00000167119
znf185
zinc finger protein 185 with LIM domain
chr20_+_46513651 1.39 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr4_+_71582090 1.39 ENSDART00000192034
si:dkey-27n6.4
si:dkey-27n6.4
chr24_+_12894282 1.38 ENSDART00000061301
si:dkeyp-28d2.4
si:dkeyp-28d2.4
chr12_+_48803098 1.38 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr13_+_35339182 1.37 ENSDART00000019323
jag1b
jagged 1b
chr8_+_25034544 1.37 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr7_-_24046999 1.34 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr3_-_34113838 1.33 ENSDART00000151216
ighv4-2
immunoglobulin heavy variable 4-2
chr10_-_44508249 1.33 ENSDART00000160018
DUSP26
dual specificity phosphatase 26
chr21_+_25198637 1.32 ENSDART00000164972
si:dkey-183i3.6
si:dkey-183i3.6
chr16_-_26855936 1.31 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr24_+_40905100 1.30 ENSDART00000167854
scn12ab
sodium channel, voltage gated, type XII, alpha b
chr18_+_3332999 1.30 ENSDART00000160857
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr12_-_28363111 1.28 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr3_-_58798377 1.28 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr20_-_37813863 1.28 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr12_+_46745239 1.26 ENSDART00000057179
plaub
plasminogen activator, urokinase b
chr20_+_53181017 1.26 ENSDART00000189692
ENSDART00000177109
FIG4
FIG4 phosphoinositide 5-phosphatase
chr10_-_13343831 1.26 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr15_-_2493771 1.25 ENSDART00000184906
neu4
sialidase 4
chr15_-_18200358 1.24 ENSDART00000158569
si:ch211-247l8.8
si:ch211-247l8.8
chr9_-_3934963 1.23 ENSDART00000062336
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr4_-_65192202 1.21 ENSDART00000168129
si:dkey-14o6.1
si:dkey-14o6.1
chr9_-_50001606 1.17 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr1_+_52392511 1.16 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr7_-_17297156 1.15 ENSDART00000161336
nitr11a
novel immune-type receptor 11a

Network of associatons between targets according to the STRING database.

First level regulatory network of gsx2+pnx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
2.0 6.0 GO:0070314 G1 to G0 transition(GO:0070314)
1.6 4.9 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.5 16.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
1.4 8.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
1.3 17.5 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.3 6.3 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
1.2 11.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
1.0 52.6 GO:0003009 skeletal muscle contraction(GO:0003009)
1.0 3.0 GO:0002369 T cell cytokine production(GO:0002369)
1.0 3.8 GO:0051660 establishment of centrosome localization(GO:0051660)
0.9 6.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.8 2.4 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.7 2.1 GO:0006089 lactate metabolic process(GO:0006089)
0.7 6.3 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.7 5.4 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.6 1.9 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.6 2.9 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.6 4.0 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.6 3.9 GO:0070207 protein homotrimerization(GO:0070207)
0.5 3.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 2.0 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.5 2.0 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.5 1.4 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.4 3.8 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.4 7.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.4 6.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3 8.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 1.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 2.6 GO:0046070 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.3 1.6 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.3 2.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 2.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.3 1.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.3 8.1 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.3 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 1.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 0.7 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.2 1.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.2 2.4 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 2.3 GO:0007608 sensory perception of smell(GO:0007608)
0.2 1.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 15.4 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.2 8.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 4.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 8.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.2 0.8 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.2 2.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.9 GO:0000710 meiotic mismatch repair(GO:0000710)
0.2 8.8 GO:0031102 neuron projection regeneration(GO:0031102)
0.2 3.5 GO:0015671 oxygen transport(GO:0015671)
0.2 0.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 8.0 GO:0030282 bone mineralization(GO:0030282)
0.2 1.7 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 1.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.2 1.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 0.8 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.2 5.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 5.9 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 5.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 11.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.5 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 2.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.5 GO:0001774 microglial cell activation(GO:0001774)
0.1 1.3 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.9 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 1.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 14.6 GO:0001756 somitogenesis(GO:0001756)
0.1 7.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 5.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.9 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.7 GO:0006415 translational termination(GO:0006415)
0.1 0.9 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 3.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 3.7 GO:0022900 electron transport chain(GO:0022900)
0.1 3.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.6 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 3.1 GO:0006414 translational elongation(GO:0006414)
0.1 4.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.9 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.2 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 2.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 2.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 3.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.6 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 3.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 3.1 GO:0042742 defense response to bacterium(GO:0042742)
0.0 2.2 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 2.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.7 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 1.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.7 GO:1990266 neutrophil migration(GO:1990266)
0.0 1.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 6.0 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 1.8 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.0 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.9 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0043967 histone H4 acetylation(GO:0043967)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 52.6 GO:0005861 troponin complex(GO:0005861)
0.7 14.4 GO:0031430 M band(GO:0031430)
0.6 4.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.6 2.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 7.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.4 5.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 2.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 33.9 GO:0030018 Z disc(GO:0030018)
0.3 3.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 2.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 8.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.8 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 7.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 11.9 GO:0001726 ruffle(GO:0001726)
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 6.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 7.6 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 5.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0071797 LUBAC complex(GO:0071797)
0.1 11.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 3.3 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.9 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 1.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 5.4 GO:0005795 Golgi stack(GO:0005795)
0.1 5.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 2.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 5.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 8.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.0 2.7 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 20.8 GO:0005739 mitochondrion(GO:0005739)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.9 GO:0009986 cell surface(GO:0009986)
0.0 19.6 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 15.4 GO:0004743 pyruvate kinase activity(GO:0004743)
2.1 14.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
1.3 17.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.2 17.4 GO:0051879 Hsp90 protein binding(GO:0051879)
1.0 11.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.8 2.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.7 2.9 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.7 3.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.6 12.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.5 4.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 13.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 3.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 2.6 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.4 4.0 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.4 1.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.3 2.3 GO:0005549 odorant binding(GO:0005549)
0.3 5.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 3.5 GO:0031720 haptoglobin binding(GO:0031720)
0.3 2.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.3 2.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.3 2.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 1.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 3.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.7 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.2 2.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 1.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 4.4 GO:0043236 laminin binding(GO:0043236)
0.2 1.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 2.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 0.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 3.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 12.8 GO:0008201 heparin binding(GO:0008201)
0.1 8.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 5.3 GO:0019843 rRNA binding(GO:0019843)
0.1 5.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 1.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 10.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 23.5 GO:0051015 actin filament binding(GO:0051015)
0.1 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.1 16.7 GO:0003779 actin binding(GO:0003779)
0.1 1.4 GO:0005112 Notch binding(GO:0005112)
0.1 6.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.9 GO:0009055 electron carrier activity(GO:0009055)
0.1 2.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 3.7 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 1.3 GO:0051020 GTPase binding(GO:0051020)
0.0 4.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 4.1 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 6.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.6 GO:0045296 cadherin binding(GO:0045296)
0.0 1.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 2.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 3.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 9.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 1.6 GO:0004519 endonuclease activity(GO:0004519)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 3.9 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 13.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 9.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 7.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 5.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 6.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.6 8.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 8.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 11.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 19.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 3.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.6 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 1.0 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway