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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hey2_hey1+heyl

Z-value: 1.01

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Transcription factors associated with hey2_hey1+heyl

Gene Symbol Gene ID Gene Info
hey2
ENSDARG00000013441 hes-related family bHLH transcription factor with YRPW motif 2
heyl
ENSDARG00000055798 hes related family bHLH transcription factor with YRPW motif like
hey1
ENSDARG00000070538 hes-related family bHLH transcription factor with YRPW motif 1
heyl
ENSDARG00000112770 hes related family bHLH transcription factor with YRPW motif like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hey2dr11_v1_chr20_-_39596338_39596338-0.448.2e-06Click!
heyldr11_v1_chr19_+_32553874_32553874-0.278.4e-03Click!
hey1dr11_v1_chr19_-_31802296_31802296-0.103.3e-01Click!

Activity profile of hey2_hey1+heyl motif

Sorted Z-values of hey2_hey1+heyl motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_60147517 11.54 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr14_+_35748385 10.73 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr14_+_35748206 10.68 ENSDART00000177391
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr20_+_34915945 10.65 ENSDART00000153064
snap25a
synaptosomal-associated protein, 25a
chr7_-_40993456 9.80 ENSDART00000031700
en2a
engrailed homeobox 2a
chr7_+_38717624 8.70 ENSDART00000132522
syt13
synaptotagmin XIII
chr2_+_29976419 8.47 ENSDART00000056748
en2b
engrailed homeobox 2b
chr7_-_30082931 7.63 ENSDART00000075600
tspan3b
tetraspanin 3b
chr8_+_21146262 7.17 ENSDART00000045684
porcn
porcupine O-acyltransferase
chr18_-_226800 7.05 ENSDART00000165180
tarsl2
threonyl-tRNA synthetase-like 2
chr2_+_21090317 6.76 ENSDART00000109568
ENSDART00000139633
pip4k2ab
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr12_-_15620090 6.46 ENSDART00000038032
acbd4
acyl-CoA binding domain containing 4
chr21_+_6780340 6.14 ENSDART00000139493
ENSDART00000140478
olfm1b
olfactomedin 1b
chr23_-_24856025 5.99 ENSDART00000142171
syt6a
synaptotagmin VIa
chr17_-_17948587 5.98 ENSDART00000090447
hhipl1
HHIP-like 1
chr1_-_39943596 5.90 ENSDART00000149730
stox2a
storkhead box 2a
chr3_-_62380146 5.85 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr22_-_12160283 5.66 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr21_+_31150438 5.61 ENSDART00000065366
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_22597362 5.53 ENSDART00000131242
cygb2
cytoglobin 2
chr21_-_42100471 5.44 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr21_+_31150773 5.43 ENSDART00000126205
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr2_-_9489611 5.33 ENSDART00000146715
st6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr2_+_20331445 5.26 ENSDART00000186880
plppr4a
phospholipid phosphatase related 4a
chr17_+_24318753 5.22 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr18_-_19103929 5.18 ENSDART00000188370
ENSDART00000177621
dennd4a
DENN/MADD domain containing 4A
chr10_-_41450367 5.10 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr11_+_45299447 4.92 ENSDART00000172999
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr15_+_16897554 4.73 ENSDART00000154679
ypel2b
yippee-like 2b
chr11_-_3959889 4.69 ENSDART00000159683
pbrm1
polybromo 1
chr18_+_14693682 4.46 ENSDART00000132249
uri1
URI1, prefoldin-like chaperone
chr23_-_21463788 4.40 ENSDART00000079265
her4.4
hairy-related 4, tandem duplicate 4
chr11_-_3552067 4.37 ENSDART00000163656
CAMK2N1
si:dkey-33m11.6
chr20_+_19212962 4.29 ENSDART00000063706
fndc4a
fibronectin type III domain containing 4a
chr12_+_24342303 4.26 ENSDART00000111239
nrxn1a
neurexin 1a
chr4_-_16824231 4.20 ENSDART00000014007
gys2
glycogen synthase 2
chr7_+_38750871 4.09 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr1_-_50859053 4.07 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr14_-_30387894 4.03 ENSDART00000176136
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr15_+_1148074 4.00 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
mlf1
myeloid leukemia factor 1
chr2_+_6181383 3.97 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr20_+_50115335 3.81 ENSDART00000031139
slc24a4b
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr4_+_5180650 3.61 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr4_-_16824556 3.60 ENSDART00000165289
ENSDART00000185839
gys2
glycogen synthase 2
chr17_-_7440397 3.60 ENSDART00000162597
grm1b
glutamate receptor, metabotropic 1b
chr20_-_14665002 3.56 ENSDART00000152816
scrn2
secernin 2
chr22_-_15569736 3.55 ENSDART00000132334
ankmy1
ankyrin repeat and MYND domain containing 1
chr19_-_5103313 3.53 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr9_-_785444 3.49 ENSDART00000012506
en1a
engrailed homeobox 1a
chr4_-_17391091 3.48 ENSDART00000056002
th2
tyrosine hydroxylase 2
chr25_+_37268900 3.45 ENSDART00000156737
si:dkey-234i14.6
si:dkey-234i14.6
chr9_+_42066030 3.39 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr14_-_32016615 3.38 ENSDART00000105761
zic3
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr11_-_3959477 3.34 ENSDART00000045971
pbrm1
polybromo 1
chr9_-_44295071 3.32 ENSDART00000011837
neurod1
neuronal differentiation 1
chr24_-_8732519 3.32 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr19_+_42469058 3.28 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr18_+_10784730 3.26 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr22_+_3238474 3.21 ENSDART00000157954
si:ch1073-178p5.3
si:ch1073-178p5.3
chr20_-_9436521 3.16 ENSDART00000133000
zgc:101840
zgc:101840
chr1_-_22834824 3.10 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr12_-_7607114 3.08 ENSDART00000158095
slc16a9b
solute carrier family 16, member 9b
chr9_+_45789887 3.08 ENSDART00000135202
si:dkey-34f9.3
si:dkey-34f9.3
chr25_+_25123385 3.00 ENSDART00000163892
ldha
lactate dehydrogenase A4
chr22_-_20105969 2.98 ENSDART00000088687
rxfp3.2b
relaxin/insulin-like family peptide receptor 3.2b
chr7_+_29167744 2.91 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr22_+_17261801 2.90 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr25_+_17689565 2.89 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr10_+_21559605 2.86 ENSDART00000123648
ENSDART00000108584
pcdh1a3
pcdh1a3
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr20_+_23440632 2.86 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr16_+_50741154 2.84 ENSDART00000101627
IGLON5
zgc:110372
chr10_-_7913591 2.82 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr5_-_18897482 2.80 ENSDART00000010101
ENSDART00000099434
aacs
acetoacetyl-CoA synthetase
chr14_+_2095394 2.79 ENSDART00000186847
CT573264.2

chr10_+_10677697 2.78 ENSDART00000188705
fam163b
family with sequence similarity 163, member B
chr14_+_24215046 2.72 ENSDART00000079215
stc2a
stanniocalcin 2a
chr19_+_9111550 2.71 ENSDART00000088336
setdb1a
SET domain, bifurcated 1a
chr25_+_3328487 2.70 ENSDART00000181143
ldhbb
lactate dehydrogenase Bb
chr8_+_17184602 2.66 ENSDART00000050228
ENSDART00000140531
dimt1l
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr24_-_6678640 2.62 ENSDART00000042478
enkur
enkurin, TRPC channel interacting protein
chr7_+_31319876 2.62 ENSDART00000187611
fam189a1
family with sequence similarity 189, member A1
chr18_-_9046805 2.61 ENSDART00000134224
grm3
glutamate receptor, metabotropic 3
chr24_+_39135419 2.61 ENSDART00000180941
tbc1d24
TBC1 domain family, member 24
chr18_+_5875268 2.56 ENSDART00000177784
ENSDART00000122009
wdr59
WD repeat domain 59
chr17_+_25414033 2.53 ENSDART00000001691
tdh2
L-threonine dehydrogenase 2
chr13_-_40316367 2.52 ENSDART00000009343
pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr8_-_23081511 2.49 ENSDART00000142015
ENSDART00000135764
ENSDART00000147021
si:dkey-70p6.1
si:dkey-70p6.1
chr2_-_44720551 2.49 ENSDART00000146380
map6d1
MAP6 domain containing 1
chr19_+_6938289 2.48 ENSDART00000139122
ENSDART00000178832
flot1b
flotillin 1b
chr24_+_2519761 2.44 ENSDART00000106619
nrn1a
neuritin 1a
chr3_+_1015867 2.43 ENSDART00000109912
si:ch1073-464p5.5
si:ch1073-464p5.5
chr14_+_41409697 2.41 ENSDART00000173335
bcorl1
BCL6 corepressor-like 1
chr18_+_6126506 2.40 ENSDART00000125725
si:ch1073-390k14.1
si:ch1073-390k14.1
chr16_-_29458806 2.38 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr19_-_30565122 2.38 ENSDART00000185650
hpcal4
hippocalcin like 4
chr8_+_25247245 2.37 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr7_-_30174882 2.36 ENSDART00000110409
frmd5
FERM domain containing 5
chr19_+_33732487 2.35 ENSDART00000010294
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr24_-_22702017 2.33 ENSDART00000179403
ctnnd2a
catenin (cadherin-associated protein), delta 2a
chr25_+_16945348 2.32 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr19_+_43563179 2.32 ENSDART00000151478
cd164l2
CD164 sialomucin-like 2
chr11_-_37411492 2.31 ENSDART00000166468
erc2
ELKS/RAB6-interacting/CAST family member 2
chr5_+_63785339 2.25 ENSDART00000050871
rgs3b
regulator of G protein signaling 3b
chr4_-_5302866 2.20 ENSDART00000138590
SNAP91 (1 of many)
si:ch211-214j24.9
chr17_+_52612866 2.20 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr2_+_49860722 2.20 ENSDART00000144060
rpl37
ribosomal protein L37
chr18_+_17428258 2.18 ENSDART00000010452
zgc:91860
zgc:91860
chr20_+_42537768 2.17 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
si:dkeyp-93d12.1
chr1_+_7956030 2.15 ENSDART00000159655
CR855320.1

chr16_-_560574 2.12 ENSDART00000148452
irx2a
iroquois homeobox 2a
chr9_+_10014817 2.11 ENSDART00000132065
nxph2a
neurexophilin 2a
chr4_+_36489448 2.11 ENSDART00000143181
znf1149
zinc finger protein 1149
chr9_-_35557397 2.10 ENSDART00000100681
ncam2
neural cell adhesion molecule 2
chr20_-_35246150 2.09 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr2_+_40294313 2.09 ENSDART00000037292
epha4b
eph receptor A4b
chr25_-_21092222 2.09 ENSDART00000154765
prr5a
proline rich 5a (renal)
chr18_+_6479963 2.09 ENSDART00000092752
ENSDART00000136333
wash1
WAS protein family homolog 1
chr23_+_21459263 2.07 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr2_+_18988407 2.07 ENSDART00000170216
glula
glutamate-ammonia ligase (glutamine synthase) a
chr12_-_30359498 2.06 ENSDART00000152981
ENSDART00000189988
tdrd1
tudor domain containing 1
chr10_+_23022263 2.02 ENSDART00000138955
si:dkey-175g6.2
si:dkey-175g6.2
chr5_+_43470544 2.00 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr22_+_438714 1.97 ENSDART00000136491
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr7_+_48999723 1.96 ENSDART00000182699
ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr10_+_17026870 1.96 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr16_+_36906693 1.95 ENSDART00000160645
si:ch73-215d9.1
si:ch73-215d9.1
chr12_-_33359654 1.93 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_+_25019387 1.93 ENSDART00000142601
stag1a
stromal antigen 1a
chr2_+_301898 1.92 ENSDART00000157246
znf1008
zinc finger protein 1008
chr11_+_25638172 1.92 ENSDART00000114226
ENSDART00000143677
grm6b
glutamate receptor, metabotropic 6b
chr14_+_36223097 1.90 ENSDART00000186872
pitx2
paired-like homeodomain 2
chr6_-_44711942 1.87 ENSDART00000055035
cntn3b
contactin 3b
chr12_-_6159545 1.86 ENSDART00000152487
rltgr
RAMP-like triterpene glycoside receptor
chr20_-_48485354 1.85 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr8_-_42238543 1.84 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr13_+_29771463 1.83 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
pax2a
paired box 2a
chr17_-_42213285 1.78 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr9_+_10014514 1.77 ENSDART00000185590
nxph2a
neurexophilin 2a
chr1_-_54420133 1.76 ENSDART00000190295
CABZ01043826.1

chr5_-_61349059 1.72 ENSDART00000136553
si:ch211-209a2.2
si:ch211-209a2.2
chr1_-_23588996 1.70 ENSDART00000102600
lcorl
ligand dependent nuclear receptor corepressor-like
chr5_+_1965296 1.70 ENSDART00000156224
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr9_+_36314867 1.69 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr9_-_403767 1.68 ENSDART00000167743
si:dkey-11f4.7
si:dkey-11f4.7
chr1_+_17695426 1.68 ENSDART00000103236
ankrd37
ankyrin repeat domain 37
chr19_+_33732188 1.66 ENSDART00000151192
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_7735153 1.66 ENSDART00000151545
slc25a38b
solute carrier family 25, member 38b
chr12_+_33038757 1.66 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr7_+_47243564 1.66 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr7_+_29163762 1.66 ENSDART00000173762
slc38a8b
solute carrier family 38, member 8b
chr10_-_16028082 1.65 ENSDART00000122540
aldh7a1
aldehyde dehydrogenase 7 family, member A1
chr18_-_11184584 1.64 ENSDART00000040500
tspan9a
tetraspanin 9a
chr21_+_40498628 1.63 ENSDART00000163454
coro6
coronin 6
chr6_-_16456093 1.62 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr8_-_19649617 1.62 ENSDART00000189033
fam78bb
family with sequence similarity 78, member B b
chr12_-_30359031 1.60 ENSDART00000192628
tdrd1
tudor domain containing 1
chr6_+_49021703 1.59 ENSDART00000149394
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr3_+_32526263 1.58 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr25_-_35113891 1.57 ENSDART00000190724
zgc:165555
zgc:165555
chr23_-_10786400 1.55 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr2_-_54639964 1.53 ENSDART00000100103
acss2l
acyl-CoA synthetase short chain family member 2 like
chr11_+_29770966 1.53 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr22_-_38034852 1.51 ENSDART00000104613
pex6
peroxisomal biogenesis factor 6
chr6_-_57539141 1.51 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr18_+_19990412 1.51 ENSDART00000155054
ENSDART00000090310
pias1b
protein inhibitor of activated STAT, 1b
chr5_-_13167097 1.49 ENSDART00000149700
ENSDART00000030213
mapk1
mitogen-activated protein kinase 1
chr11_-_43948885 1.48 ENSDART00000164522
CABZ01074203.1

chr5_+_45990046 1.48 ENSDART00000084024
sv2c
synaptic vesicle glycoprotein 2C
chr1_+_12195700 1.47 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr22_-_38035084 1.47 ENSDART00000145029
pex6
peroxisomal biogenesis factor 6
chr3_+_20156956 1.46 ENSDART00000125281
ngfra
nerve growth factor receptor a (TNFR superfamily, member 16)
chr18_+_27489595 1.46 ENSDART00000182018
tp53i11b
tumor protein p53 inducible protein 11b
chr13_+_27768898 1.46 ENSDART00000029521
asrgl1
asparaginase like 1
chr6_-_42111937 1.44 ENSDART00000181772
grm2a
glutamate receptor, metabotropic 2a
chr7_+_20031202 1.42 ENSDART00000052904
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr2_-_49860723 1.40 ENSDART00000083690
blvra
biliverdin reductase A
chr5_-_27994679 1.40 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr4_-_211714 1.39 ENSDART00000172566
ptpro
protein tyrosine phosphatase, receptor type, O
chr5_+_27583445 1.39 ENSDART00000136488
zmat4a
zinc finger, matrin-type 4a
chr21_-_41617372 1.39 ENSDART00000187171
BX005397.1

chr6_+_13117093 1.39 ENSDART00000138668
casp8l1
caspase 8, apoptosis-related cysteine peptidase, like 1
chr2_-_10188598 1.37 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr15_-_11956981 1.37 ENSDART00000164163
si:dkey-202l22.3
si:dkey-202l22.3
chr18_-_21218851 1.37 ENSDART00000060160
calb2a
calbindin 2a
chr8_-_25761544 1.36 ENSDART00000078152
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr1_-_25438934 1.35 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr6_+_48978202 1.35 ENSDART00000150023
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr10_+_2684958 1.35 ENSDART00000112019
setd9
SET domain containing 9
chr11_+_24800156 1.35 ENSDART00000131976
adipor1a
adiponectin receptor 1a
chr3_+_32526799 1.35 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr23_+_32101361 1.33 ENSDART00000138849
zgc:56699
zgc:56699
chr7_+_22543963 1.32 ENSDART00000101528
chrnb1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr3_+_40841897 1.31 ENSDART00000150081
ENSDART00000126096
mmd2a
monocyte to macrophage differentiation-associated 2a
chr13_+_30572172 1.31 ENSDART00000010052
ENSDART00000144417
ppifa
peptidylprolyl isomerase Fa
chr19_-_23550179 1.31 ENSDART00000136959
pimr75
Pim proto-oncogene, serine/threonine kinase, related 75
chr2_+_22659787 1.31 ENSDART00000043956
zgc:161973
zgc:161973
chr6_-_10591607 1.30 ENSDART00000151376
dnah9l
dynein, axonemal, heavy polypeptide 9 like
chr10_-_6775271 1.30 ENSDART00000110735
zgc:194281
zgc:194281
chr18_-_20466061 1.30 ENSDART00000060311
paqr5a
progestin and adipoQ receptor family member Va
chr8_-_31606514 1.30 ENSDART00000018886
ghra
growth hormone receptor a

Network of associatons between targets according to the STRING database.

First level regulatory network of hey2_hey1+heyl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0061355 Wnt protein secretion(GO:0061355)
1.4 11.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.2 3.5 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
1.1 4.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.1 13.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
1.1 5.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.8 2.5 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.8 2.3 GO:0042245 RNA repair(GO:0042245)
0.7 8.0 GO:0030719 P granule organization(GO:0030719)
0.7 2.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.7 4.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.7 4.0 GO:0089718 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.6 1.8 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.6 4.1 GO:0006953 acute-phase response(GO:0006953) positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.6 1.7 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.4 5.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 1.2 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.4 1.9 GO:0061072 iris morphogenesis(GO:0061072)
0.4 1.5 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.3 5.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 10.7 GO:0016082 synaptic vesicle priming(GO:0016082)
0.3 1.4 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.3 14.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 2.5 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.3 4.1 GO:0021754 facial nucleus development(GO:0021754)
0.3 2.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 5.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 0.9 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.3 2.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.3 9.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 2.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.3 5.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.3 1.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.3 5.5 GO:0015671 oxygen transport(GO:0015671)
0.3 2.1 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.3 1.5 GO:0001919 regulation of receptor recycling(GO:0001919)
0.3 1.5 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 3.2 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.2 1.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.8 GO:0021588 cerebellum formation(GO:0021588)
0.2 2.3 GO:0045117 azole transport(GO:0045117)
0.2 4.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 2.3 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.2 2.7 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 4.4 GO:0009749 response to glucose(GO:0009749)
0.2 4.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.0 GO:0021516 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.2 0.6 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.2 2.1 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 0.5 GO:0042766 nucleosome mobilization(GO:0042766)
0.2 8.4 GO:0030901 midbrain development(GO:0030901)
0.2 0.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 2.4 GO:0032264 IMP salvage(GO:0032264)
0.2 9.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.2 1.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.6 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.5 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 1.2 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 2.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.2 2.7 GO:0031167 rRNA methylation(GO:0031167)
0.1 1.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.0 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:0034553 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 1.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.5 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.4 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.9 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 3.4 GO:0006829 zinc II ion transport(GO:0006829)
0.1 2.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.9 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.3 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.7 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 0.5 GO:0036088 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.1 0.4 GO:0016038 absorption of visible light(GO:0016038)
0.1 1.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.9 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.6 GO:0086011 membrane repolarization during action potential(GO:0086011) membrane repolarization during cardiac muscle cell action potential(GO:0086013) cardiac muscle cell membrane repolarization(GO:0099622)
0.1 1.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0048478 replication fork protection(GO:0048478)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 2.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 6.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 3.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.1 2.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 1.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 0.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 4.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 1.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.2 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.9 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.2 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 0.8 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 5.2 GO:0001666 response to hypoxia(GO:0001666)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 1.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0003151 outflow tract morphogenesis(GO:0003151) rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661) atrial cardiac muscle cell development(GO:0055014)
0.0 6.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 2.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.9 GO:0007286 spermatid development(GO:0007286)
0.0 3.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 3.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 12.0 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 3.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.0 GO:0050821 protein stabilization(GO:0050821)
0.0 0.7 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 1.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 4.7 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.2 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.4 GO:0032094 response to food(GO:0032094)
0.0 11.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 2.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 1.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.8 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 1.1 GO:0010906 regulation of carbohydrate metabolic process(GO:0006109) regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 1.0 GO:0001878 response to yeast(GO:0001878)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 2.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.3 GO:0014074 response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.4 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 3.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.8 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.6 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.5 GO:0007266 Rho protein signal transduction(GO:0007266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.1 17.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.0 8.0 GO:0016586 RSC complex(GO:0016586)
1.0 5.9 GO:0070062 extracellular exosome(GO:0070062)
1.0 2.9 GO:0033391 chromatoid body(GO:0033391)
0.6 2.5 GO:0016600 flotillin complex(GO:0016600)
0.5 2.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.5 21.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 1.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.4 1.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.4 2.1 GO:0071203 WASH complex(GO:0071203)
0.3 2.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.8 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 1.4 GO:0071546 pi-body(GO:0071546)
0.2 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 5.4 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.2 7.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 4.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 3.4 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.6 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 3.5 GO:0043204 perikaryon(GO:0043204)
0.1 2.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.4 GO:0043195 terminal bouton(GO:0043195)
0.1 2.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.7 GO:0043186 P granule(GO:0043186)
0.1 4.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 14.7 GO:0070382 exocytic vesicle(GO:0070382)
0.1 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 3.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.3 GO:0008278 cohesin complex(GO:0008278)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.7 GO:0044545 NSL complex(GO:0044545)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 11.9 GO:0045202 synapse(GO:0045202)
0.0 1.2 GO:0016342 catenin complex(GO:0016342)
0.0 1.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 8.5 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 1.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 20.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.4 21.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.4 11.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.1 4.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.9 11.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.8 5.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.8 5.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.7 3.6 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.7 3.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.7 5.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 3.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.6 2.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.6 4.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.6 4.0 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 3.6 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.5 2.5 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.5 2.0 GO:0004903 growth hormone receptor activity(GO:0004903)
0.5 5.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 4.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 3.1 GO:0030274 LIM domain binding(GO:0030274)
0.4 1.3 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.4 3.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 3.2 GO:0004067 asparaginase activity(GO:0004067)
0.4 5.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.4 1.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 14.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 2.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 2.3 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.3 1.9 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.3 0.8 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.3 10.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 1.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 6.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 0.7 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 5.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.6 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.2 5.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 1.5 GO:0043121 neurotrophin binding(GO:0043121)
0.2 1.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.5 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 6.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.2 1.4 GO:0034584 piRNA binding(GO:0034584)
0.2 0.8 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 0.5 GO:0052834 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 2.8 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.2 1.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 2.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.0 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 2.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 6.5 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 4.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 3.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 6.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.0 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 1.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 3.3 GO:0071949 FAD binding(GO:0071949)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 3.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 3.2 GO:0015297 antiporter activity(GO:0015297)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 41.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.3 GO:0019239 deaminase activity(GO:0019239)
0.0 4.6 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 1.7 GO:0022834 ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.0 0.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 2.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 9.3 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 7.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 16.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.8 11.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.5 4.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 5.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 2.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 6.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 1.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 1.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation