ISMARA results: hic1

Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation

Downloads

Results for hic1

Z-value: 0.91

Motif logo

Transcription factors associated with hic1

Gene Symbol	Gene ID	Gene Info
hic1 NCBI UniProt	ENSDARG00000055493	hypermethylated in cancer 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
hic1	dr11_v1_chr15_+_25683069_25683069	-0.25	1.6e-02	Click!

Activity profile of hic1 motif

Sorted Z-values of hic1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_55728559 Show fit	13.15	ENSDART00000186201	CT583728.14 NCBI UniProt Show fit
chr4_+_55778679 Show fit	12.42	ENSDART00000183009	CT583728.19 NCBI UniProt Show fit
chr4_+_55794876 Show fit	12.42	ENSDART00000189043	CT583728.17 NCBI UniProt Show fit
chr4_+_55810436 Show fit	12.42	ENSDART00000182875	CT583728.16 NCBI UniProt Show fit
chr4_-_68568233 Show fit	12.42	ENSDART00000184284	BX548011.1 NCBI UniProt Show fit
chr4_-_77561679 Show fit	11.62	ENSDART00000180809	AL935186.9 NCBI UniProt Show fit
chr14_-_21064199 Show fit	10.64	ENSDART00000172099	si:dkey-74k8.3 NCBI UniProt Show fit	si:dkey-74k8.3
chr14_-_21063977 Show fit	9.83	ENSDART00000164373	si:dkey-74k8.3 NCBI UniProt Show fit	si:dkey-74k8.3
chr6_+_28203 Show fit	9.76	ENSDART00000191561	CZQB01141835.1 NCBI UniProt Show fit
chr4_-_77557279 Show fit	8.63	ENSDART00000180113	AL935186.10 NCBI UniProt Show fit

Showing 1 to 10 of 52 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of hic1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
4.1	20.5	GO:0010332	response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2	7.0	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	6.5	GO:0001947	heart looping(GO:0001947)
0.1	5.7	GO:0007596	blood coagulation(GO:0007596)
0.3	4.6	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.9	4.3	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	3.8	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.8	3.2	GO:0006114	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1	2.4	GO:0014003	oligodendrocyte development(GO:0014003)
0.4	2.2	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)

Showing 1 to 10 of 23 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.3	4.6	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	4.3	GO:0005730	nucleolus(GO:0005730)
0.1	1.9	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.8	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)

Showing 1 to 6 of 6 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.0	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.8	6.5	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	5.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.3	4.6	GO:0043994	H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.3	4.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2	3.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	2.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	2.0	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	1.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.9	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)

Showing 1 to 10 of 13 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.3	5.7	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	3.8	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	2.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Showing 1 to 7 of 7 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis

Showing 1 to 2 of 2 entries

Results for hic1

Z-value: 0.91

Motif logo

Transcription factors associated with hic1

Activity-expression correlation:

Activity profile of hic1 motif

Sorted Z-values of hic1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of hic1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: