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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hnf4a+hnf4b

Z-value: 4.57

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Transcription factors associated with hnf4a+hnf4b

Gene Symbol Gene ID Gene Info
hnf4a
ENSDARG00000021494 hepatocyte nuclear factor 4, alpha
hnf4b
ENSDARG00000104742 hepatic nuclear factor 4, beta
hnf4a
ENSDARG00000112985 hepatocyte nuclear factor 4, alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf4adr11_v1_chr23_+_25832689_258326890.904.9e-34Click!
CABZ01057488.1dr11_v1_chr7_+_69019851_690198510.886.9e-31Click!

Activity profile of hnf4a+hnf4b motif

Sorted Z-values of hnf4a+hnf4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23913943 156.24 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr20_+_1412193 139.48 ENSDART00000064419
leg1.1
liver-enriched gene 1, tandem duplicate 1
chr20_+_1398564 115.45 ENSDART00000002242
leg1.2
liver-enriched gene 1, tandem duplicate 2
chr1_+_17900306 109.48 ENSDART00000089480
cyp4v8
cytochrome P450, family 4, subfamily V, polypeptide 8
chr15_-_26552393 101.89 ENSDART00000150152
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr1_+_53374454 88.09 ENSDART00000038807
ucp1
uncoupling protein 1
chr15_-_26552652 87.13 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr16_+_23923746 86.54 ENSDART00000137962
si:dkey-7f3.14
si:dkey-7f3.14
chr17_-_30702411 86.30 ENSDART00000114358
zgc:194392
zgc:194392
chr19_+_9277327 85.66 ENSDART00000104623
ENSDART00000151164
si:rp71-15k1.1
si:rp71-15k1.1
chr2_-_37960688 83.10 ENSDART00000055565
cbln14
cerebellin 14
chr7_+_25036188 78.50 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr2_-_37956768 72.62 ENSDART00000034595
cbln10
cerebellin 10
chr10_+_17026870 72.41 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr13_-_22843562 71.98 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr8_-_30791266 70.51 ENSDART00000062220
gstt1a
glutathione S-transferase theta 1a
chr22_-_20126230 68.70 ENSDART00000138688
creb3l3a
cAMP responsive element binding protein 3-like 3a
chr9_-_9982696 68.03 ENSDART00000192548
ENSDART00000125852
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr18_+_17611627 67.91 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr8_+_30699429 66.82 ENSDART00000005345
upb1
ureidopropionase, beta
chr20_-_40754794 64.67 ENSDART00000187251
cx32.3
connexin 32.3
chr8_+_1766206 64.35 ENSDART00000021820
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr14_+_21107032 63.72 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr22_+_37888249 63.64 ENSDART00000076082
fetub
fetuin B
chr16_+_23947196 61.79 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr21_-_27443995 61.58 ENSDART00000003508
bfb
complement component bfb
chr16_-_17197546 61.49 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr25_-_20049449 60.77 ENSDART00000104315
zgc:136858
zgc:136858
chr16_+_23924040 60.28 ENSDART00000161124
si:dkey-7f3.14
si:dkey-7f3.14
chr8_-_37263524 59.74 ENSDART00000061327
rh50
Rh50-like protein
chr12_-_6172154 58.85 ENSDART00000185434
a1cf
apobec1 complementation factor
chr10_-_322769 58.66 ENSDART00000165244
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr3_-_45848257 57.34 ENSDART00000147198
igfals
insulin-like growth factor binding protein, acid labile subunit
chr17_+_20173882 57.19 ENSDART00000155379
si:ch211-248a14.8
si:ch211-248a14.8
chr18_+_40462445 54.91 ENSDART00000087645
ugt5c2
UDP glucuronosyltransferase 5 family, polypeptide C2
chr16_-_17200120 54.79 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr22_-_24818066 51.46 ENSDART00000143443
vtg6
vitellogenin 6
chr10_+_26747755 50.37 ENSDART00000100329
f9b
coagulation factor IXb
chr7_+_52135791 49.40 ENSDART00000098705
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr8_+_39802506 48.47 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr2_+_22659787 47.40 ENSDART00000043956
zgc:161973
zgc:161973
chr2_+_3533458 47.21 ENSDART00000133007
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr2_-_37967368 45.87 ENSDART00000050345
cbln9
cerebellin 9
chr3_+_16762483 45.19 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr25_-_26758253 44.69 ENSDART00000123004
si:dkeyp-73b11.8
si:dkeyp-73b11.8
chr6_-_1768724 43.70 ENSDART00000162488
ENSDART00000163613
zgc:158417
zgc:158417
chr13_-_40726865 42.79 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr16_+_23921610 42.28 ENSDART00000143855
apoa4b.3
apolipoprotein A-IV b, tandem duplicate 3
chr18_+_18861359 42.27 ENSDART00000144605
pllp
plasmolipin
chr23_-_27702561 42.18 ENSDART00000053876
dnajc22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr17_+_20174044 41.90 ENSDART00000156028
si:ch211-248a14.8
si:ch211-248a14.8
chr13_+_50375800 40.35 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr5_-_69940868 38.84 ENSDART00000185924
ENSDART00000097357
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr16_+_32029090 37.75 ENSDART00000041054
tmc4
transmembrane channel-like 4
chr24_-_17047918 37.45 ENSDART00000020204
msrb2
methionine sulfoxide reductase B2
chr2_-_24407933 35.15 ENSDART00000088584
si:dkey-208k22.6
si:dkey-208k22.6
chr2_+_3533117 35.09 ENSDART00000132572
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr6_+_27624023 34.57 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr5_-_62317496 33.63 ENSDART00000180089
zgc:85789
zgc:85789
chr16_+_23921777 33.08 ENSDART00000163213
apoa4b.3
apolipoprotein A-IV b, tandem duplicate 3
chr17_-_49407091 32.35 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr20_+_54304800 30.77 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr23_-_24488696 30.66 ENSDART00000155593
tmem82
transmembrane protein 82
chr16_-_25607266 30.57 ENSDART00000192602
zgc:110410
zgc:110410
chr23_-_44786844 30.33 ENSDART00000148669
si:ch73-269m23.5
si:ch73-269m23.5
chr8_-_65189 29.94 ENSDART00000168412
hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
chr5_-_3839285 29.01 ENSDART00000122292
mlxipl
MLX interacting protein like
chr13_+_8696825 28.99 ENSDART00000109059
ttc7a
tetratricopeptide repeat domain 7A
chr24_-_36727922 28.42 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr3_+_12744083 28.07 ENSDART00000158554
ENSDART00000169545
cyp2k21
cytochrome P450, family 2, subfamily k, polypeptide 21
chr17_-_2584423 28.06 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr15_-_24178893 27.44 ENSDART00000077980
pipox
pipecolic acid oxidase
chr19_+_31532043 27.33 ENSDART00000136289
tmem64
transmembrane protein 64
chr5_-_3885727 26.90 ENSDART00000143250
mlxipl
MLX interacting protein like
chr12_-_5120339 25.97 ENSDART00000168759
rbp4
retinol binding protein 4, plasma
chr18_-_43866001 25.33 ENSDART00000150218
treh
trehalase (brush-border membrane glycoprotein)
chr23_+_9522942 25.32 ENSDART00000137751
osbpl2b
oxysterol binding protein-like 2b
chr1_-_9641845 25.22 ENSDART00000121490
ENSDART00000159411
ugt5b2
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr6_-_2627488 24.98 ENSDART00000044089
ENSDART00000158333
ENSDART00000155109
hyi
hydroxypyruvate isomerase
chr3_-_3496738 24.91 ENSDART00000186849
CABZ01040998.1

chr16_+_16969060 24.62 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr9_-_9977827 24.60 ENSDART00000187315
ENSDART00000010246
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr12_-_5120175 24.29 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr15_+_15403560 23.80 ENSDART00000049831
dhrs11b
dehydrogenase/reductase (SDR family) member 11b
chr20_+_2281933 22.85 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr22_+_21549419 22.74 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr2_-_5728843 22.51 ENSDART00000014020
sst2
somatostatin 2
chr16_+_16968682 22.29 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr19_-_27564458 22.12 ENSDART00000123155
si:dkeyp-46h3.6
si:dkeyp-46h3.6
chr21_+_8533533 22.04 ENSDART00000077924
FO834888.1

chr7_-_24520866 21.76 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr20_-_43741159 21.69 ENSDART00000192621
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr12_-_31457301 21.36 ENSDART00000043887
ENSDART00000148603
acsl5
acyl-CoA synthetase long chain family member 5
chr11_+_30296332 21.35 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr17_+_450956 21.31 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr15_+_26603395 20.90 ENSDART00000188667
slc47a3
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr18_-_43866526 20.88 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr17_-_2573021 20.72 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr16_-_25606889 20.60 ENSDART00000077447
ENSDART00000131528
zgc:110410
zgc:110410
chr10_-_11385155 20.33 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr8_-_8698607 20.12 ENSDART00000046712
zgc:86609
zgc:86609
chr15_-_1885247 19.57 ENSDART00000149703
porb
P450 (cytochrome) oxidoreductase b
chr24_-_26369185 19.53 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr17_+_15216022 19.46 ENSDART00000138831
gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr23_+_9522781 19.19 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr17_-_2578026 19.17 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr9_+_8380728 18.55 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr16_+_54875530 18.32 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr21_-_30111134 18.27 ENSDART00000014223
slc23a1
solute carrier family 23 (ascorbic acid transporter), member 1
chr1_-_12064715 18.11 ENSDART00000143628
ENSDART00000103406
pla2g12a
phospholipase A2, group XIIA
chr17_-_2595736 18.03 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr8_+_6576940 17.99 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr2_-_24407732 17.81 ENSDART00000180612
ENSDART00000153688
ENSDART00000179913
si:dkey-208k22.6
si:dkey-208k22.6
chr4_-_19693978 17.79 ENSDART00000100974
ENSDART00000040405
snd1
staphylococcal nuclease and tudor domain containing 1
chr11_+_14281100 17.70 ENSDART00000193664
ENSDART00000161597
si:ch211-262i1.3
si:ch211-262i1.3
chr14_+_9009600 17.51 ENSDART00000133904
si:ch211-274f20.2
si:ch211-274f20.2
chr8_+_47099033 16.97 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr17_-_17948587 16.93 ENSDART00000090447
hhipl1
HHIP-like 1
chr17_-_2590222 16.88 ENSDART00000185711
CR759892.1

chr3_-_50139860 16.76 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr18_-_46183462 16.61 ENSDART00000021192
kcnk6
potassium channel, subfamily K, member 6
chr2_+_6067371 16.37 ENSDART00000053868
ENSDART00000145244
aldh9a1b
aldehyde dehydrogenase 9 family, member A1b
chr8_-_25329967 15.94 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr6_+_53429228 15.24 ENSDART00000165067
abhd14b
abhydrolase domain containing 14B
chr7_-_52417060 15.24 ENSDART00000148579
myzap
myocardial zonula adherens protein
chr1_+_24387659 15.21 ENSDART00000130356
qdprb2
quinoid dihydropteridine reductase b2
chr8_-_20838342 14.97 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr5_-_20205075 14.74 ENSDART00000051611
dao.3
D-amino-acid oxidase, tandem duplicate 3
chr22_+_29994093 14.10 ENSDART00000104778
si:dkey-286j15.3
si:dkey-286j15.3
chr8_-_33154677 13.85 ENSDART00000133300
zbtb34
zinc finger and BTB domain containing 34
chr12_-_33706726 13.69 ENSDART00000153135
myo15b
myosin XVB
chr23_+_46183410 13.51 ENSDART00000167596
ENSDART00000151149
ENSDART00000150896
btr31
bloodthirsty-related gene family, member 31
chr21_+_25236297 13.22 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr20_-_46128590 12.95 ENSDART00000123744
taar1b
trace amine associated receptor 1b
chr2_-_22927958 12.81 ENSDART00000141621
myo7bb
myosin VIIBb
chr22_+_24645325 12.80 ENSDART00000159531
lpar3
lysophosphatidic acid receptor 3
chr9_-_38036984 12.55 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr2_+_24536762 12.51 ENSDART00000144149
angptl4
angiopoietin-like 4
chr22_+_15323930 12.34 ENSDART00000142416
si:dkey-236e20.3
si:dkey-236e20.3
chr5_+_31959954 12.24 ENSDART00000142826
myo1hb
myosin IHb
chr2_-_22927581 12.08 ENSDART00000109515
myo7bb
myosin VIIBb
chr15_+_6459847 11.91 ENSDART00000157250
ENSDART00000065824
bace2
beta-site APP-cleaving enzyme 2
chr3_-_23643751 11.86 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr3_+_39099716 11.80 ENSDART00000083388
tmem98
transmembrane protein 98
chr7_-_26457208 11.29 ENSDART00000173519
zgc:172079
zgc:172079
chr6_-_43047774 11.22 ENSDART00000161722
glyctk
glycerate kinase
chr22_+_15331214 11.19 ENSDART00000136566
sult3st4
sulfotransferase family 3, cytosolic sulfotransferase 4
chr4_+_1283068 11.01 ENSDART00000167233
chrm2a
cholinergic receptor, muscarinic 2a
chr21_-_37194669 10.95 ENSDART00000192748
fgfr4
fibroblast growth factor receptor 4
chr10_+_8875195 10.88 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr9_+_21383620 10.73 ENSDART00000130023
ENSDART00000062656
ENSDART00000180081
cryl1
crystallin, lambda 1
chr20_+_5106568 10.65 ENSDART00000028039
cyp46a1.1
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1
chr7_+_24520518 10.52 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr3_+_31662126 10.42 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr5_+_9218318 10.18 ENSDART00000137774
si:ch211-12e13.1
si:ch211-12e13.1
chr15_-_30857350 9.91 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr11_-_24347644 9.88 ENSDART00000089777
si:ch211-15p9.2
si:ch211-15p9.2
chr19_-_18130567 9.50 ENSDART00000190659
ENSDART00000022803
snx10a
sorting nexin 10a
chr6_+_28051978 9.43 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr25_-_12803723 9.35 ENSDART00000158787
ca5a
carbonic anhydrase Va
chr22_-_11648094 9.28 ENSDART00000191791
dpp4
dipeptidyl-peptidase 4
chr5_-_44843738 8.82 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr24_-_32150276 8.51 ENSDART00000166212
cubn
cubilin (intrinsic factor-cobalamin receptor)
chr18_-_7400075 8.41 ENSDART00000101250
si:dkey-30c15.13
si:dkey-30c15.13
chr20_+_43379029 8.36 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr12_-_20362041 8.25 ENSDART00000184145
ENSDART00000105952
aqp8a.2
aquaporin 8a, tandem duplicate 2
chr21_-_13055195 8.12 ENSDART00000133517
myorg
myogenesis regulating glycosidase (putative)
chr18_+_26829086 7.96 ENSDART00000098356
slc28a1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr22_-_24992532 7.91 ENSDART00000102751
si:dkey-179j5.5
si:dkey-179j5.5
chr3_-_15470944 7.88 ENSDART00000185302
spns1
spinster homolog 1 (Drosophila)
chr21_-_37194365 7.88 ENSDART00000100286
fgfr4
fibroblast growth factor receptor 4
chr12_+_22607761 7.87 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr25_+_5288665 7.80 ENSDART00000169540
CABZ01039861.1

chr13_-_303137 7.79 ENSDART00000099131
chs1
chitin synthase 1
chr20_+_39250673 7.62 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr11_-_30364847 7.58 ENSDART00000078387
pecr
peroxisomal trans-2-enoyl-CoA reductase
chr2_-_38261272 7.52 ENSDART00000143743
si:ch211-14a17.10
si:ch211-14a17.10
chr13_+_5013572 6.88 ENSDART00000162425
psap
prosaposin
chr23_-_21758253 6.82 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr15_+_34069746 6.40 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr22_-_7050 6.39 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr7_+_26100024 6.36 ENSDART00000173726
si:ch211-196f2.3
si:ch211-196f2.3
chr25_+_418932 6.31 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr6_+_55819038 5.92 ENSDART00000108786
si:ch211-81n22.1
si:ch211-81n22.1
chr4_+_35590588 5.82 ENSDART00000183582
si:dkeyp-4c4.2
si:dkeyp-4c4.2
chr6_-_35046735 5.81 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr18_+_26829362 5.80 ENSDART00000132728
slc28a1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr3_+_27770110 5.61 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr20_-_26937453 5.60 ENSDART00000139756
ftr97
finTRIM family, member 97
chr15_+_19797918 5.56 ENSDART00000113314
si:ch211-229d2.5
si:ch211-229d2.5
chr2_+_28453338 5.49 ENSDART00000020456
mmp15b
matrix metallopeptidase 15b
chr17_+_23926796 5.27 ENSDART00000021177
pex13
peroxisomal biogenesis factor 13
chr5_+_32815745 5.11 ENSDART00000181535
crata
carnitine O-acetyltransferase a
chr7_+_73444325 5.02 ENSDART00000123016
si:ch211-142d6.2
si:ch211-142d6.2
chr10_+_8197827 4.90 ENSDART00000026244
mtrex
Mtr4 exosome RNA helicase
chr19_-_27564980 4.82 ENSDART00000171967
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr5_-_24112175 4.77 ENSDART00000131595
si:ch211-114c12.5
si:ch211-114c12.5
chr2_+_47249179 4.65 ENSDART00000144438
si:ch211-284d12.3
si:ch211-284d12.3
chr22_-_16400484 4.60 ENSDART00000135987
lama3
laminin, alpha 3
chr20_-_26936887 4.46 ENSDART00000160827
ftr79
finTRIM family, member 79

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4a+hnf4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
36.5 109.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
22.6 67.9 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
15.4 46.2 GO:0005991 trehalose metabolic process(GO:0005991)
13.9 139.5 GO:1990402 embryonic liver development(GO:1990402)
13.4 66.8 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
11.0 88.1 GO:1990845 adaptive thermogenesis(GO:1990845)
9.4 37.5 GO:0030091 protein repair(GO:0030091)
7.5 59.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
7.2 50.3 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
7.1 21.4 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
6.9 27.4 GO:0046440 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
6.3 18.8 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
6.1 18.3 GO:0015882 L-ascorbic acid transport(GO:0015882)
5.1 86.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
4.3 12.8 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
4.2 58.9 GO:0016556 mRNA modification(GO:0016556)
3.7 14.7 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
3.6 317.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
3.6 25.0 GO:0046487 glyoxylate metabolic process(GO:0046487)
3.5 55.3 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
3.2 116.3 GO:0050821 protein stabilization(GO:0050821)
3.1 40.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.0 72.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.8 11.0 GO:0010459 cardiac conduction system development(GO:0003161) negative regulation of heart rate(GO:0010459)
2.7 15.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
2.5 7.6 GO:1903173 fatty alcohol metabolic process(GO:1903173)
2.5 9.9 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
2.3 16.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
2.2 32.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
2.1 51.5 GO:0032355 response to estradiol(GO:0032355)
2.0 86.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
1.9 25.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.9 9.5 GO:0070986 left/right axis specification(GO:0070986)
1.7 48.5 GO:0003323 type B pancreatic cell development(GO:0003323)
1.6 12.5 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
1.6 65.6 GO:0006749 glutathione metabolic process(GO:0006749)
1.6 7.8 GO:0046349 amino sugar biosynthetic process(GO:0046349)
1.5 10.6 GO:0006707 steroid catabolic process(GO:0006706) cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.5 15.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.4 218.0 GO:0042157 lipoprotein metabolic process(GO:0042157)
1.2 11.9 GO:0050435 beta-amyloid metabolic process(GO:0050435)
1.1 3.3 GO:0045218 zonula adherens maintenance(GO:0045218)
1.0 5.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.0 11.9 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
1.0 6.8 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.9 49.4 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.9 13.8 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.9 18.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.9 42.3 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.9 7.9 GO:0090398 cellular senescence(GO:0090398)
0.8 3.4 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.8 112.2 GO:0055123 digestive system development(GO:0055123)
0.7 50.4 GO:0007596 blood coagulation(GO:0007596)
0.6 61.6 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.6 9.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.6 4.2 GO:0032475 otolith formation(GO:0032475)
0.6 2.9 GO:2000562 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5 5.3 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.5 48.1 GO:0007605 sensory perception of sound(GO:0007605)
0.5 12.6 GO:0030497 fatty acid elongation(GO:0030497)
0.4 12.2 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.4 10.6 GO:0051923 sulfation(GO:0051923)
0.4 2.9 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.3 3.7 GO:0036368 cone photoresponse recovery(GO:0036368)
0.3 4.2 GO:0030534 adult behavior(GO:0030534)
0.3 11.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.3 22.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 49.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.2 2.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 1.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 5.5 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 4.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 3.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 28.0 GO:0006869 lipid transport(GO:0006869)
0.1 4.1 GO:0006826 iron ion transport(GO:0006826)
0.1 16.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.0 GO:0042664 negative regulation of cell fate specification(GO:0009996) negative regulation of endodermal cell fate specification(GO:0042664)
0.1 6.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 61.1 GO:0016567 protein ubiquitination(GO:0016567)
0.1 3.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 2.7 GO:0030488 tRNA methylation(GO:0030488)
0.1 4.0 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.1 11.5 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.1 19.6 GO:0009725 response to hormone(GO:0009725)
0.1 0.6 GO:0098927 protein targeting to lysosome(GO:0006622) early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.3 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 4.6 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 7.6 GO:0016197 endosomal transport(GO:0016197)
0.0 3.7 GO:0006364 rRNA processing(GO:0006364)
0.0 7.1 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 2.5 GO:0006401 RNA catabolic process(GO:0006401)
0.0 6.4 GO:0006412 translation(GO:0006412)
0.0 2.8 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 2.5 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.2 53.0 GO:0061689 tricellular tight junction(GO:0061689)
4.5 67.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
2.2 17.8 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.8 20.1 GO:0072546 ER membrane protein complex(GO:0072546)
1.8 5.3 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
1.5 9.3 GO:0031258 lamellipodium membrane(GO:0031258)
1.2 3.7 GO:0034457 Mpp10 complex(GO:0034457)
1.0 7.8 GO:0030428 cell septum(GO:0030428)
0.7 24.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.7 889.8 GO:0005615 extracellular space(GO:0005615)
0.5 3.3 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.5 55.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.5 328.9 GO:0005576 extracellular region(GO:0005576)
0.5 20.1 GO:0005902 microvillus(GO:0005902)
0.4 15.9 GO:0032587 ruffle membrane(GO:0032587)
0.3 19.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.3 4.2 GO:0005922 connexon complex(GO:0005922)
0.3 24.9 GO:0016459 myosin complex(GO:0016459)
0.2 109.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.2 163.3 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.2 103.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 5.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 4.4 GO:0005811 lipid particle(GO:0005811)
0.1 819.8 GO:0016021 integral component of membrane(GO:0016021)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 45.4 GO:0005739 mitochondrion(GO:0005739)
0.0 2.9 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
29.1 116.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
22.0 88.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
15.4 46.2 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
14.3 42.8 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
9.4 37.5 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
8.0 63.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
7.8 86.0 GO:0035804 structural constituent of egg coat(GO:0035804)
7.4 51.5 GO:0045735 nutrient reservoir activity(GO:0045735)
7.2 50.3 GO:0034632 retinol transporter activity(GO:0034632)
6.8 40.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
5.6 45.2 GO:0016803 ether hydrolase activity(GO:0016803)
5.5 16.4 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
4.9 19.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
4.6 32.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
4.6 27.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
4.2 245.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
4.0 71.9 GO:0035497 cAMP response element binding(GO:0035497)
3.8 15.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
3.7 14.7 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
3.1 12.6 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
2.9 8.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
2.8 67.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
2.8 42.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.8 11.2 GO:0008887 glycerate kinase activity(GO:0008887)
2.6 297.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.5 9.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.4 59.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
1.9 21.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
1.8 10.6 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
1.6 63.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
1.6 54.0 GO:0004364 glutathione transferase activity(GO:0004364)
1.5 30.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.5 40.0 GO:0015248 sterol transporter activity(GO:0015248)
1.4 18.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.4 40.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.4 5.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
1.3 18.4 GO:0042910 xenobiotic transporter activity(GO:0042910)
1.3 5.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
1.2 77.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.2 8.2 GO:0015250 water channel activity(GO:0015250)
1.2 5.8 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
1.1 37.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.1 3.3 GO:0070097 delta-catenin binding(GO:0070097)
1.0 88.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
1.0 11.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.0 7.8 GO:0004100 chitin synthase activity(GO:0004100)
0.9 22.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.9 109.5 GO:0004497 monooxygenase activity(GO:0004497)
0.9 12.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.8 4.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.8 20.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.8 10.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.8 53.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.6 11.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 9.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.5 9.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 3.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 101.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 21.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 62.1 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.4 3.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.4 16.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.4 2.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.3 19.5 GO:0048029 monosaccharide binding(GO:0048029)
0.3 52.2 GO:0016853 isomerase activity(GO:0016853)
0.3 197.1 GO:0008289 lipid binding(GO:0008289)
0.3 2.9 GO:0016936 galactoside binding(GO:0016936)
0.3 7.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 53.4 GO:0030246 carbohydrate binding(GO:0030246)
0.2 13.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 3.7 GO:0030515 snoRNA binding(GO:0030515)
0.2 104.9 GO:0046983 protein dimerization activity(GO:0046983)
0.2 13.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 14.4 GO:0051082 unfolded protein binding(GO:0051082)
0.1 8.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 22.5 GO:0005179 hormone activity(GO:0005179)
0.1 3.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 24.9 GO:0003774 motor activity(GO:0003774)
0.1 11.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.9 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 4.0 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 57.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 6.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 8.1 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 4.9 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 1.2 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 28.5 GO:0005525 GTP binding(GO:0005525)
0.0 5.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 4.4 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 6.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 24.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 10.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.5 GO:0008080 N-acetyltransferase activity(GO:0008080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 112.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.8 116.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.5 3.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.4 64.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 4.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 49.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 17.8 PID CMYB PATHWAY C-MYB transcription factor network
0.3 11.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.3 6.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 12.1 PID FGF PATHWAY FGF signaling pathway
0.1 3.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 12.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 180.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
8.4 66.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
7.7 46.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
7.2 57.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
6.4 76.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
4.5 18.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
4.3 34.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
4.3 29.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
2.8 16.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
2.7 48.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
2.7 21.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
2.1 18.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.1 19.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.1 71.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.8 9.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.7 12.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6 52.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.4 5.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 18.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 3.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 49.6 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.2 24.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 4.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 6.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 12.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 7.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 10.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 6.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation