Project
PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
Navigation
Downloads
Results for hnf4g
Z-value: 1.14
Motif logo
Transcription factors associated with hnf4g
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hnf4g | dr11_v1_chr24_-_23675446_23675446 | 0.70 | 3.7e-15 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_24818066 Show fit | 22.53 |
ENSDART00000143443
|
vitellogenin 6 |
|
| chr22_-_24738188 Show fit | 19.23 |
ENSDART00000050238
|
vitellogenin 1 |
|
| chr8_+_30699429 Show fit | 19.11 |
ENSDART00000005345
|
ureidopropionase, beta |
|
| chr21_-_27443995 Show fit | 18.77 |
ENSDART00000003508
|
complement component bfb |
|
| chr17_-_2590222 Show fit | 18.72 |
ENSDART00000185711
|
|
|
| chr17_-_2573021 Show fit | 18.11 |
ENSDART00000074181
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr15_-_16012963 Show fit | 17.04 |
ENSDART00000144138
|
HNF1 homeobox Ba |
|
| chr17_-_2578026 Show fit | 16.49 |
ENSDART00000065821
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr22_+_16022211 Show fit | 15.56 |
ENSDART00000062618
|
serpin peptidase inhibitor, clade C (antithrombin), member 1 |
|
| chr17_-_2584423 Show fit | 14.88 |
ENSDART00000013506
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hnf4g
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 64.0 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 1.1 | 41.8 | GO:0032355 | response to estradiol(GO:0032355) |
| 3.8 | 19.1 | GO:0019483 | beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) |
| 0.2 | 18.8 | GO:0006956 | complement activation(GO:0006956) |
| 2.8 | 17.0 | GO:0021571 | rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572) |
| 5.2 | 15.6 | GO:2000257 | regulation of protein activation cascade(GO:2000257) |
| 0.1 | 14.8 | GO:0002040 | sprouting angiogenesis(GO:0002040) |
| 0.2 | 11.8 | GO:0042737 | drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) |
| 1.1 | 10.9 | GO:1901571 | icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571) |
| 3.6 | 10.8 | GO:0034375 | high-density lipoprotein particle remodeling(GO:0034375) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 65.8 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 46.0 | GO:0005576 | extracellular region(GO:0005576) |
| 0.7 | 10.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 7.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 6.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.6 | 4.8 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.6 | 3.5 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.6 | 3.2 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.3 | 3.0 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.0 | 2.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.8 | 64.0 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 6.0 | 41.8 | GO:0045735 | nutrient reservoir activity(GO:0045735) |
| 0.3 | 25.7 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.0 | 24.3 | GO:0046983 | protein dimerization activity(GO:0046983) |
| 0.1 | 16.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.1 | 15.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 1.5 | 14.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 12.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.2 | 11.8 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.4 | 10.8 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 15.6 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 5.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 5.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.9 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 2.6 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 1.8 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 1.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 0.8 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.1 | PID BARD1 PATHWAY | BARD1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 19.1 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 1.3 | 15.6 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 1.0 | 12.5 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.9 | 7.4 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.5 | 7.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.3 | 5.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 1.1 | 4.4 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.2 | 3.2 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.5 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 2.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |