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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hnf4g

Z-value: 1.14

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Transcription factors associated with hnf4g

Gene Symbol Gene ID Gene Info
hnf4g
ENSDARG00000071565 hepatocyte nuclear factor 4, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf4gdr11_v1_chr24_-_23675446_236754460.703.7e-15Click!

Activity profile of hnf4g motif

Sorted Z-values of hnf4g motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_24818066 22.53 ENSDART00000143443
vtg6
vitellogenin 6
chr22_-_24738188 19.23 ENSDART00000050238
vtg1
vitellogenin 1
chr8_+_30699429 19.11 ENSDART00000005345
upb1
ureidopropionase, beta
chr21_-_27443995 18.77 ENSDART00000003508
bfb
complement component bfb
chr17_-_2590222 18.72 ENSDART00000185711
CR759892.1

chr17_-_2573021 18.11 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr15_-_16012963 17.04 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr17_-_2578026 16.49 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr22_+_16022211 15.56 ENSDART00000062618
serpinc1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_-_2584423 14.88 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr6_-_607063 14.83 ENSDART00000189900
lgals2b
lectin, galactoside-binding, soluble, 2b
chr4_-_77114795 14.63 ENSDART00000144849
CU467646.2

chr17_-_2595736 14.57 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr10_+_19569052 14.14 ENSDART00000058425
CABZ01059627.1

chr17_+_20173882 13.22 ENSDART00000155379
si:ch211-248a14.8
si:ch211-248a14.8
chr9_+_8380728 12.10 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr18_+_17611627 10.77 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr17_-_30702411 9.93 ENSDART00000114358
zgc:194392
zgc:194392
chr20_-_25522911 8.50 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr16_+_26846495 7.87 ENSDART00000078124
trim35-29
tripartite motif containing 35-29
chr8_-_49207319 7.47 ENSDART00000022870
fam110a
family with sequence similarity 110, member A
chr6_+_27624023 7.38 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr4_-_17725008 7.33 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr17_+_20174044 7.29 ENSDART00000156028
si:ch211-248a14.8
si:ch211-248a14.8
chr5_-_69180587 7.13 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr13_-_40726865 7.12 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr13_+_50375800 7.01 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr3_+_16762483 6.86 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr8_+_24745041 6.59 ENSDART00000148872
slc16a4
solute carrier family 16, member 4
chr7_-_24520866 6.58 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr5_-_69180227 5.96 ENSDART00000154816
zgc:171967
zgc:171967
chr8_+_39802506 5.79 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr5_-_62317496 5.66 ENSDART00000180089
zgc:85789
zgc:85789
chr23_+_19790962 5.39 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr11_-_5563498 4.76 ENSDART00000160835
pex11g
peroxisomal biogenesis factor 11 gamma
chr9_+_29994439 4.56 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr1_-_12064715 4.36 ENSDART00000143628
ENSDART00000103406
pla2g12a
phospholipase A2, group XIIA
chr16_+_11623956 4.26 ENSDART00000137788
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr8_-_20838342 4.24 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr17_-_6076266 4.21 ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr1_-_9644630 4.13 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr22_-_24992532 4.09 ENSDART00000102751
si:dkey-179j5.5
si:dkey-179j5.5
chr17_+_50701748 3.52 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr21_-_43428040 3.29 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr3_+_12764894 3.27 ENSDART00000166071
cyp2k16
cytochrome P450, family 2, subfamily K, polypeptide16
chr9_-_44953664 3.19 ENSDART00000188558
ENSDART00000185210
vil1
villin 1
chr24_+_7828097 3.10 ENSDART00000134975
zgc:101569
zgc:101569
chr7_-_52417060 3.09 ENSDART00000148579
myzap
myocardial zonula adherens protein
chr14_-_16810401 3.04 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_-_46128590 3.01 ENSDART00000123744
taar1b
trace amine associated receptor 1b
chr12_-_10567188 2.92 ENSDART00000144283
myof
myoferlin
chr13_-_35908275 2.88 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr7_-_26518086 2.81 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr16_+_11660839 2.75 ENSDART00000193911
ENSDART00000143683
si:dkey-250k15.10
si:dkey-250k15.10
chr21_-_31290582 2.60 ENSDART00000065362
ca4c
carbonic anhydrase IV c
chr17_-_6076084 2.58 ENSDART00000058890
ephx2
epoxide hydrolase 2, cytoplasmic
chr4_-_170120 2.57 ENSDART00000171333
eps8
epidermal growth factor receptor pathway substrate 8
chr2_-_10877765 2.51 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr23_+_2740741 2.50 ENSDART00000134938
zgc:114123
zgc:114123
chr13_-_35907768 2.49 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr14_+_9009600 2.43 ENSDART00000133904
si:ch211-274f20.2
si:ch211-274f20.2
chr21_-_11856143 2.37 ENSDART00000151204
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr25_+_29472361 2.36 ENSDART00000154857
il17rel
interleukin 17 receptor E-like
chr9_+_1138802 2.19 ENSDART00000191130
ENSDART00000187308
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr21_-_5879897 2.08 ENSDART00000184034
rpl35
ribosomal protein L35
chr15_-_31366742 2.05 ENSDART00000125585
or111-3
odorant receptor, family D, subfamily 111, member 3
chr12_-_33706726 2.05 ENSDART00000153135
myo15b
myosin XVB
chr19_-_25519310 1.86 ENSDART00000089882
C1GALT1 (1 of many)
si:dkey-202e17.1
chr9_+_1138323 1.83 ENSDART00000190352
ENSDART00000190387
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr15_-_30857350 1.80 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr7_+_29115890 1.79 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr7_-_29341233 1.76 ENSDART00000140938
ENSDART00000147251
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr24_-_32150276 1.76 ENSDART00000166212
cubn
cubilin (intrinsic factor-cobalamin receptor)
chr6_+_59029485 1.68 ENSDART00000050140
CABZ01088367.1

chr22_-_11438627 1.68 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr3_-_27868183 1.64 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr24_-_36175365 1.61 ENSDART00000065338
pak1ip1
PAK1 interacting protein 1
chr15_+_34069746 1.57 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr20_-_49657134 1.57 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr16_+_9495583 1.42 ENSDART00000150750
ENSDART00000150457
pimr208
Pim proto-oncogene, serine/threonine kinase, related 208
chr1_-_57129179 1.38 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
si:ch73-94k4.2
chr22_-_20376488 1.38 ENSDART00000140187
zbtb7a
zinc finger and BTB domain containing 7a
chr9_+_48415043 1.32 ENSDART00000159930
lrp2a
low density lipoprotein receptor-related protein 2a
chr1_-_9485939 1.31 ENSDART00000157814
micall2b
mical-like 2b
chr4_+_57099307 1.28 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr15_+_8192715 1.26 ENSDART00000156442
ENSDART00000077660
mipep
mitochondrial intermediate peptidase
chr21_-_43474012 1.23 ENSDART00000065104
tmem185
transmembrane protein 185
chr4_+_21741228 1.23 ENSDART00000112035
ENSDART00000127664
myf5
myogenic factor 5
chr16_+_54875530 1.20 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr7_+_24520518 1.19 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr23_-_40776046 1.17 ENSDART00000136230
DUPD1 (1 of many)
si:dkeyp-27c8.1
chr4_-_72468168 1.16 ENSDART00000182995
ENSDART00000174067
CR788316.1

chr7_+_24951552 1.08 ENSDART00000173644
mark2b
MAP/microtubule affinity-regulating kinase 2b
chr11_+_19068442 1.08 ENSDART00000171766
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr2_+_37897079 1.01 ENSDART00000141784
tep1
telomerase-associated protein 1
chr23_+_44461493 0.99 ENSDART00000149854
si:ch1073-228j22.1
si:ch1073-228j22.1
chr6_-_46474483 0.98 ENSDART00000155761
rdh20
retinol dehydrogenase 20
chr25_+_8316953 0.97 ENSDART00000154598
muc2.2
mucin 2.2, oligomeric mucus/gel-forming
chr6_-_10788065 0.91 ENSDART00000190968
wipf1b
WAS/WASL interacting protein family, member 1b
chr13_-_50309969 0.90 ENSDART00000191597
CU928131.1

chr7_-_29115772 0.90 ENSDART00000076386
fbxl8
F-box and leucine-rich repeat protein 8
chr20_+_29436601 0.83 ENSDART00000136804
fmn1
formin 1
chr5_-_65319387 0.83 ENSDART00000164649
col27a1b
collagen, type XXVII, alpha 1b
chr7_-_39738460 0.77 ENSDART00000052201
ccdc96
coiled-coil domain containing 96
chr1_-_59169815 0.70 ENSDART00000100163
wu:fk65c09
wu:fk65c09
chr20_+_43379029 0.69 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr19_+_10536093 0.65 ENSDART00000138706
si:dkey-211g8.1
si:dkey-211g8.1
chr12_+_22607761 0.64 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr13_-_303137 0.64 ENSDART00000099131
chs1
chitin synthase 1
chr25_+_5288665 0.63 ENSDART00000169540
CABZ01039861.1

chr17_+_2734331 0.61 ENSDART00000067542
kcnk10b
potassium channel, subfamily K, member 10b
chr15_-_2632891 0.56 ENSDART00000081840
cldnj
claudin j
chr25_+_22216723 0.51 ENSDART00000051291
hexa
hexosaminidase A (alpha polypeptide)
chr5_-_30080332 0.50 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr12_+_33916939 0.43 ENSDART00000149292
trim8b
tripartite motif containing 8b
chr1_-_52167509 0.41 ENSDART00000184935
BX901942.2

chr7_+_31398775 0.38 ENSDART00000124820
si:ch211-150j10.4
si:ch211-150j10.4
chr4_+_53145525 0.34 ENSDART00000166960
si:dkey-8o9.2
si:dkey-8o9.2
chr8_+_23390844 0.26 ENSDART00000184556
si:dkey-16n15.6
si:dkey-16n15.6
chr16_+_48460873 0.18 ENSDART00000159902
ext1a
exostosin glycosyltransferase 1a
chr8_-_22157301 0.17 ENSDART00000158383
nphp4
nephronophthisis 4
chr20_+_539852 0.15 ENSDART00000185994
dse
dermatan sulfate epimerase
chr11_-_27827442 0.15 ENSDART00000121847
ENSDART00000132018
ENSDART00000145744
ENSDART00000134677
ENSDART00000130800
cstf1
cleavage stimulation factor, 3' pre-RNA, subunit 1
chr23_+_17437554 0.13 ENSDART00000184282
BX649300.3

chr19_+_18983900 0.09 ENSDART00000161005
cmtm8a
CKLF-like MARVEL transmembrane domain containing 8a
chr23_-_2448234 0.07 ENSDART00000082097
LO018513.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4g

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.6 GO:2000257 regulation of protein activation cascade(GO:2000257)
3.8 19.1 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
3.8 64.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
3.6 10.8 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
2.8 17.0 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
1.1 10.9 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
1.1 41.8 GO:0032355 response to estradiol(GO:0032355)
0.8 3.2 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.8 4.8 GO:0016559 peroxisome fission(GO:0016559)
0.6 1.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 7.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 4.0 GO:0006857 oligopeptide transport(GO:0006857)
0.3 1.6 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 2.5 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.3 6.8 GO:0060841 venous blood vessel development(GO:0060841)
0.2 11.8 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 3.0 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 5.8 GO:0003323 type B pancreatic cell development(GO:0003323)
0.2 18.8 GO:0006956 complement activation(GO:0006956)
0.1 2.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.3 GO:0070293 renal absorption(GO:0070293)
0.1 0.6 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 2.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 3.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 14.8 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 6.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 2.8 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 1.6 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 3.8 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.1 1.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 2.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.5 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 7.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 2.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.7 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 1.8 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.8 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 1.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.3 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 6.6 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.9 GO:0030048 actin filament-based movement(GO:0030048)
0.0 2.8 GO:0060047 heart contraction(GO:0060047)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 3.2 GO:0032433 filopodium tip(GO:0032433)
0.6 4.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6 3.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 3.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 65.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.6 GO:0030428 cell septum(GO:0030428)
0.1 6.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 46.0 GO:0005576 extracellular region(GO:0005576)
0.0 7.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 41.8 GO:0045735 nutrient reservoir activity(GO:0045735)
5.8 64.0 GO:0035804 structural constituent of egg coat(GO:0035804)
2.4 7.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
2.3 6.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.5 14.8 GO:0016936 galactoside binding(GO:0016936)
1.5 7.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
1.4 6.9 GO:0016803 ether hydrolase activity(GO:0016803)
1.1 4.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 4.0 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.5 7.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.4 10.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 1.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 25.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.3 7.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.0 GO:0051117 ATPase binding(GO:0051117)
0.2 2.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 11.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 3.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 15.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.6 GO:0004100 chitin synthase activity(GO:0004100)
0.1 16.2 GO:0030246 carbohydrate binding(GO:0030246)
0.1 3.5 GO:0005178 integrin binding(GO:0005178)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 12.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 2.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 24.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 3.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0004875 complement receptor activity(GO:0004875)
0.0 2.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.3 GO:0042562 hormone binding(GO:0042562)
0.0 2.6 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 5.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 2.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 19.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.3 15.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.1 4.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.0 12.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.9 7.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.5 7.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 5.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 3.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation