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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxa4a+hoxc3a

Z-value: 0.67

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Transcription factors associated with hoxa4a+hoxc3a

Gene Symbol Gene ID Gene Info
hoxc3a
ENSDARG00000070339 homeobox C3a
hoxa4a
ENSDARG00000103862 homeobox A4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa3adr11_v1_chr19_+_19777437_197774370.295.2e-03Click!
hoxc3adr11_v1_chr23_+_36106790_36106790-0.141.9e-01Click!

Activity profile of hoxa4a+hoxc3a motif

Sorted Z-values of hoxa4a+hoxc3a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_20110086 7.31 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr19_-_5369486 4.42 ENSDART00000105004
krt17
keratin 17
chr22_-_10459880 4.20 ENSDART00000064801
ogn
osteoglycin
chr5_-_71705191 3.79 ENSDART00000187767
ak1
adenylate kinase 1
chr15_-_12011390 3.58 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr4_+_73085993 3.54 ENSDART00000165749
si:ch73-170d6.2
si:ch73-170d6.2
chr21_-_32060993 3.42 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr11_-_1550709 3.24 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr2_+_11205795 3.23 ENSDART00000019078
lhx8a
LIM homeobox 8a
chr15_-_46779934 3.22 ENSDART00000085136
clcn2c
chloride channel 2c
chr5_+_56023186 3.20 ENSDART00000156230
fzd9a
frizzled class receptor 9a
chr6_-_54815886 3.14 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr10_-_22095505 3.03 ENSDART00000140210
ponzr10
plac8 onzin related protein 10
chr7_+_31891110 2.99 ENSDART00000173883
mybpc3
myosin binding protein C, cardiac
chr22_+_19407531 2.74 ENSDART00000141060
si:dkey-78l4.2
si:dkey-78l4.2
chr17_+_16046314 2.71 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr25_+_29160102 2.69 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr12_-_464007 2.51 ENSDART00000106669
dhrs7cb
dehydrogenase/reductase (SDR family) member 7Cb
chr25_+_5035343 2.38 ENSDART00000011751
parvb
parvin, beta
chr12_-_33357655 2.37 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr8_-_23780334 2.35 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr2_+_6253246 2.30 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr17_+_16046132 2.23 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr3_+_27798094 2.22 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr19_+_2631565 2.21 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr24_+_22731228 2.21 ENSDART00000146733
si:dkey-225k4.1
si:dkey-225k4.1
chr22_+_6254194 2.19 ENSDART00000112388
ENSDART00000135176
rnasel4
ribonuclease like 4
chr8_+_22516728 2.15 ENSDART00000146013
si:ch211-261n11.3
si:ch211-261n11.3
chr8_-_36287046 2.11 ENSDART00000162877
si:busm1-194e12.11
si:busm1-194e12.11
chr10_-_35257458 2.10 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr21_+_25777425 1.95 ENSDART00000021620
cldnd
claudin d
chr17_-_37395460 1.91 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr25_+_37293312 1.86 ENSDART00000086737
ENSDART00000161595
si:dkey-234i14.9
si:dkey-234i14.9
chr24_-_33291784 1.84 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr18_-_48550426 1.80 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr3_-_16784280 1.78 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
si:dkey-30j10.5
chr9_+_44994214 1.74 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr24_+_19415124 1.74 ENSDART00000186931
sulf1
sulfatase 1
chr18_-_46258612 1.71 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr24_-_40744672 1.71 ENSDART00000160672
CU633479.1

chr7_-_71389375 1.68 ENSDART00000128928
CABZ01074298.1

chr22_-_38621438 1.68 ENSDART00000098330
nppc
natriuretic peptide C
chr19_+_41464870 1.68 ENSDART00000102778
dlx6a
distal-less homeobox 6a
chr9_-_35633827 1.65 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr19_-_25149598 1.65 ENSDART00000162917
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr24_-_27452488 1.65 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr20_-_9462433 1.65 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr19_-_5103141 1.64 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr8_-_31107537 1.63 ENSDART00000098925
vgll4l
vestigial like 4 like
chr2_+_5371492 1.62 ENSDART00000139762
si:ch1073-184j22.1
si:ch1073-184j22.1
chr8_+_31717175 1.62 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr10_-_21362071 1.61 ENSDART00000125167
avd
avidin
chr6_+_28208973 1.60 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr10_-_21362320 1.60 ENSDART00000189789
avd
avidin
chr12_+_22580579 1.59 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr18_-_40708537 1.57 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr18_-_48547564 1.57 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr16_-_42056137 1.55 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr18_+_23408073 1.50 ENSDART00000136489
mctp2a
multiple C2 domains, transmembrane 2a
chr24_-_25166720 1.49 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr20_+_36812368 1.48 ENSDART00000062931
abracl
ABRA C-terminal like
chr19_-_5103313 1.43 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr9_+_31795343 1.43 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr18_+_924949 1.43 ENSDART00000170888
ENSDART00000193163
pkma
pyruvate kinase M1/2a
chr17_+_16429826 1.40 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr22_-_30770751 1.38 ENSDART00000172115
AL831726.2

chr23_+_28322986 1.38 ENSDART00000134710
birc5b
baculoviral IAP repeat containing 5b
chr22_-_10121880 1.38 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr12_+_23912074 1.37 ENSDART00000152864
svila
supervillin a
chr16_-_20312146 1.32 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr14_+_46313396 1.31 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr7_+_34620418 1.30 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr19_+_46158078 1.30 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr20_-_37813863 1.27 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr3_+_18555899 1.27 ENSDART00000163036
ENSDART00000158791
cbx4
chromobox homolog 4 (Pc class homolog, Drosophila)
chr5_+_32206378 1.26 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr25_+_36292057 1.24 ENSDART00000152329
bmb
brambleberry
chr19_+_43297546 1.22 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr10_+_33393829 1.22 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr3_-_15734358 1.21 ENSDART00000137325
mvp
major vault protein
chr21_-_43015383 1.21 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr2_-_15324837 1.21 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr3_+_1182315 1.19 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr21_-_26490186 1.19 ENSDART00000009889
zgc:110540
zgc:110540
chr12_-_46176115 1.18 ENSDART00000152848
si:ch211-226h7.8
si:ch211-226h7.8
chr12_-_48188928 1.17 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr20_+_29209615 1.17 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr20_-_23426339 1.16 ENSDART00000004625
zar1
zygote arrest 1
chr3_-_34084387 1.16 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr20_-_29864390 1.15 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr1_+_53842344 1.14 ENSDART00000114506
crfb17
cytokine receptor family member B17
chr5_+_63302660 1.13 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr16_+_23799622 1.13 ENSDART00000046922
rab13
RAB13, member RAS oncogene family
chr22_+_19366866 1.13 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr22_+_737211 1.13 ENSDART00000017305
znf76
zinc finger protein 76
chr14_-_1355544 1.12 ENSDART00000060417
cetn4
centrin 4
chr13_-_35808904 1.11 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr11_-_2131280 1.11 ENSDART00000008409
calcoco1b
calcium binding and coiled-coil domain 1b
chr19_+_26923274 1.11 ENSDART00000148439
ENSDART00000148877
nelfe
negative elongation factor complex member E
chr10_+_15025006 1.09 ENSDART00000145192
ENSDART00000140084
si:dkey-88l16.5
si:dkey-88l16.5
chr17_+_8799451 1.09 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr9_+_38372216 1.09 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr23_-_36446307 1.08 ENSDART00000136623
zgc:174906
zgc:174906
chr24_-_9300160 1.08 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr2_+_20793982 1.08 ENSDART00000014785
prg4a
proteoglycan 4a
chr9_+_30421489 1.08 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr10_+_15024772 1.07 ENSDART00000135667
si:dkey-88l16.5
si:dkey-88l16.5
chr15_-_43284021 1.06 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_+_44699734 1.06 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr6_+_7414215 1.05 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr5_-_4418555 1.05 ENSDART00000170158
apooa
apolipoprotein O, a
chr3_-_15734530 1.05 ENSDART00000141142
mvp
major vault protein
chr7_-_59165640 1.04 ENSDART00000170853
haus6
HAUS augmin-like complex, subunit 6
chr11_+_37250839 1.03 ENSDART00000170209
il17rc
interleukin 17 receptor C
chr1_+_513986 1.03 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr2_+_36112273 0.99 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr4_+_77943184 0.99 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr3_-_16719244 0.98 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_11988065 0.98 ENSDART00000005140
med27
mediator complex subunit 27
chr24_+_1023839 0.97 ENSDART00000082526
zgc:111976
zgc:111976
chr17_-_49978986 0.97 ENSDART00000154728
col12a1a
collagen, type XII, alpha 1a
chr21_+_15592426 0.97 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr8_-_23776399 0.95 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr23_+_45966436 0.94 ENSDART00000172160
CABZ01069338.1

chr13_+_9432501 0.93 ENSDART00000058064
zgc:123321
zgc:123321
chr16_-_51271962 0.93 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr23_+_2728095 0.92 ENSDART00000066086
zgc:114123
zgc:114123
chr19_+_4888491 0.91 ENSDART00000151540
cdk12
cyclin-dependent kinase 12
chr22_-_20166660 0.91 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr16_+_54209504 0.90 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr20_+_29209767 0.89 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr1_-_55248496 0.89 ENSDART00000098615
nanos3
nanos homolog 3
chr13_+_4871886 0.88 ENSDART00000132301
micu1
mitochondrial calcium uptake 1
chr11_-_20096018 0.86 ENSDART00000030420
ogfrl2
opioid growth factor receptor-like 2
chr10_+_44700103 0.86 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr6_+_21001264 0.85 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr22_-_21476836 0.85 ENSDART00000135977
s1pr3a
sphingosine-1-phosphate receptor 3a
chr5_+_66433287 0.85 ENSDART00000170757
kntc1
kinetochore associated 1
chr3_-_27713180 0.84 ENSDART00000180151
CR394572.1

chr13_+_33117528 0.84 ENSDART00000085719
si:ch211-10a23.2
si:ch211-10a23.2
chr10_-_2971407 0.83 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr6_+_16468776 0.82 ENSDART00000109151
ENSDART00000114667
zgc:161969
zgc:161969
chr14_+_3038473 0.81 ENSDART00000026021
ENSDART00000150000
cd74a
CD74 molecule, major histocompatibility complex, class II invariant chain a
chr8_+_30664077 0.80 ENSDART00000138750
adora2aa
adenosine A2a receptor a
chr10_+_31951338 0.79 ENSDART00000019416
lhfpl6
LHFPL tetraspan subfamily member 6
chr23_-_24394719 0.78 ENSDART00000044918
epha2b
eph receptor A2 b
chr24_-_37640705 0.78 ENSDART00000066583
zgc:112496
zgc:112496
chr24_-_36680261 0.78 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr2_+_10007113 0.78 ENSDART00000155213
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr7_+_17816006 0.78 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr24_+_17260001 0.77 ENSDART00000066765
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr4_+_21129752 0.77 ENSDART00000169764
syt1a
synaptotagmin Ia
chr22_+_14051894 0.77 ENSDART00000142548
aox6
aldehyde oxidase 6
chr14_-_413273 0.76 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr6_-_55399214 0.75 ENSDART00000168367
ctsa
cathepsin A
chr21_-_37075542 0.75 ENSDART00000129439
BX649250.1

chr14_-_25935167 0.74 ENSDART00000139855
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_54497730 0.73 ENSDART00000157722
tmem203
transmembrane protein 203
chr21_-_14251306 0.73 ENSDART00000114715
ENSDART00000181380
man1b1a
mannosidase, alpha, class 1B, member 1a
chr11_-_11791718 0.72 ENSDART00000180476
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr7_-_28148310 0.71 ENSDART00000044208
lmo1
LIM domain only 1
chr8_-_38355268 0.70 ENSDART00000129597
sorbs3
sorbin and SH3 domain containing 3
chr1_-_51710225 0.70 ENSDART00000057601
ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr19_-_5358443 0.70 ENSDART00000105036
cyt1l
type I cytokeratin, enveloping layer, like
chr15_+_12429206 0.70 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr5_-_3927692 0.69 ENSDART00000146840
ENSDART00000058346
c1qbp
complement component 1, q subcomponent binding protein
chr3_-_12930217 0.69 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr3_+_1637358 0.69 ENSDART00000180266
CR394546.5

chr24_+_16547035 0.69 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_+_17775247 0.69 ENSDART00000112356
si:ch211-150o23.3
si:ch211-150o23.3
chr9_+_18829360 0.69 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr7_-_8052829 0.68 ENSDART00000172931
si:ch211-163c2.2
si:ch211-163c2.2
chr24_+_36204028 0.68 ENSDART00000063832
ENSDART00000155260
rbbp8
retinoblastoma binding protein 8
chr7_+_22543963 0.68 ENSDART00000101528
chrnb1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr9_-_710896 0.68 ENSDART00000180478
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr1_+_54952540 0.68 ENSDART00000182944
r3hcc1l
R3H domain and coiled-coil containing 1-like
chr24_+_17260329 0.68 ENSDART00000129554
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr18_+_27571448 0.68 ENSDART00000147886
cd82b
CD82 molecule b
chr11_+_44356504 0.67 ENSDART00000160678
srsf7b
serine/arginine-rich splicing factor 7b
chr3_-_402714 0.67 ENSDART00000134062
ENSDART00000105659
mhc1zja
major histocompatibility complex class I ZJA
chr3_-_20040636 0.66 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr13_+_45431660 0.66 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr14_+_33329420 0.66 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr20_+_29209926 0.66 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr8_-_52229462 0.66 ENSDART00000185949
ENSDART00000051825
tcf7l1b
transcription factor 7 like 1b
chr16_+_13818500 0.66 ENSDART00000135245
flcn
folliculin
chr12_-_19119176 0.65 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr22_-_6229275 0.65 ENSDART00000146045
ENSDART00000179730
si:ch211-274k16.2
si:ch211-274k16.2
chr23_+_31107685 0.64 ENSDART00000103448
tbx18
T-box 18
chr5_+_40485503 0.64 ENSDART00000051055
ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr22_+_18156000 0.64 ENSDART00000143483
ENSDART00000136133
nr2c2ap
nuclear receptor 2C2-associated protein
chr7_+_36898850 0.63 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr6_+_6797520 0.63 ENSDART00000150967
si:ch211-85n16.3
si:ch211-85n16.3
chr21_+_28958471 0.62 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_24165371 0.62 ENSDART00000173472
si:ch211-216p19.5
si:ch211-216p19.5
chr23_+_29885019 0.62 ENSDART00000167059
aurkaip1
aurora kinase A interacting protein 1
chr11_+_44356707 0.62 ENSDART00000165219
srsf7b
serine/arginine-rich splicing factor 7b
chr7_-_4125021 0.61 ENSDART00000167182
ENSDART00000173696
zgc:55733
zgc:55733
chr9_-_27398369 0.60 ENSDART00000186499
tex30
testis expressed 30
chr12_-_44019561 0.59 ENSDART00000165900
si:dkey-31i7.1
si:dkey-31i7.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa4a+hoxc3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.6 1.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 1.9 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.6 3.0 GO:0003210 cardiac atrium formation(GO:0003210)
0.5 1.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 2.9 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.4 2.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 1.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 1.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.3 0.8 GO:0060907 dendritic cell antigen processing and presentation(GO:0002468) macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 1.2 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 1.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 1.4 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.2 0.7 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.2 3.8 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 1.7 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.2 10.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.2 0.9 GO:0000012 single strand break repair(GO:0000012)
0.2 0.7 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.2 1.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 1.5 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.2 0.5 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.9 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 1.1 GO:0072091 forebrain anterior/posterior pattern specification(GO:0021797) regulation of stem cell proliferation(GO:0072091)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.4 GO:0097435 fibril organization(GO:0097435)
0.1 0.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.7 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.1 0.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.5 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 1.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 3.0 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.9 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.6 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 3.0 GO:0051014 actin filament severing(GO:0051014)
0.1 3.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 1.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.8 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.1 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.0 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.5 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.3 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 2.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 1.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.4 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.7 GO:0035141 medial fin morphogenesis(GO:0035141)
0.1 1.3 GO:0014823 response to activity(GO:0014823)
0.1 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.1 4.1 GO:0006096 glycolytic process(GO:0006096)
0.1 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.0 GO:0046549 retinal cone cell development(GO:0046549)
0.1 3.2 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 3.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 3.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 2.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.0 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.2 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 4.5 GO:0031101 fin regeneration(GO:0031101)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0031179 peptide modification(GO:0031179)
0.0 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 2.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.5 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.6 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.2 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 1.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0051297 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.2 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:1903828 negative regulation of cellular protein localization(GO:1903828)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.4 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.6 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.2 10.5 GO:0005861 troponin complex(GO:0005861)
0.2 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.5 GO:0032021 NELF complex(GO:0032021)
0.2 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0055087 Ski complex(GO:0055087)
0.1 1.0 GO:0035060 brahma complex(GO:0035060)
0.1 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.9 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 0.7 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.6 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818)
0.1 2.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 5.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.5 GO:0043186 P granule(GO:0043186)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 3.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 2.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.4 GO:0009986 cell surface(GO:0009986)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 3.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.0 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 3.4 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.7 4.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 3.2 GO:0009374 biotin binding(GO:0009374)
0.4 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 1.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 1.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.3 3.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 7.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 0.8 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 3.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.7 GO:0070336 flap-structured DNA binding(GO:0070336)
0.2 3.8 GO:0032190 acrosin binding(GO:0032190)
0.2 2.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.7 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 3.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 3.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.3 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.9 GO:0030332 cyclin binding(GO:0030332)
0.1 1.0 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.7 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.4 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.7 GO:0008494 translation activator activity(GO:0008494)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.7 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.1 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 3.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 2.2 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.8 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 8.0 GO:0005525 GTP binding(GO:0005525)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.9 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.1 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase