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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxa5a

Z-value: 0.37

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Transcription factors associated with hoxa5a

Gene Symbol Gene ID Gene Info
hoxa5a
ENSDARG00000102501 homeobox A5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa5adr11_v1_chr19_+_19759577_197595770.122.5e-01Click!

Activity profile of hoxa5a motif

Sorted Z-values of hoxa5a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_34065573 2.11 ENSDART00000186946
pbx3b
pre-B-cell leukemia homeobox 3b
chr13_+_27316632 1.70 ENSDART00000016121
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr14_-_30490763 1.63 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
micu3b
mitochondrial calcium uptake family, member 3b
chr3_-_62380146 1.36 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr7_-_69983462 1.34 ENSDART00000123380
KCNIP4
potassium voltage-gated channel interacting protein 4
chr5_-_71460556 1.34 ENSDART00000108804
brinp1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr13_+_27316934 1.31 ENSDART00000164533
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr15_-_28200049 1.27 ENSDART00000004200
sarm1
sterile alpha and TIR motif containing 1
chr24_+_11105786 1.18 ENSDART00000175182
prlh2
prolactin releasing hormone 2
chr6_-_39475304 1.12 ENSDART00000022761
scn8ab
sodium channel, voltage gated, type VIII, alpha subunit b
chr25_-_20523927 1.08 ENSDART00000114448
si:ch211-269c21.2
si:ch211-269c21.2
chr3_-_30061985 1.06 ENSDART00000189583
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr12_+_28574863 1.02 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr21_+_11509461 0.98 ENSDART00000134620
entpd2b
ectonucleoside triphosphate diphosphohydrolase 2b
chr1_-_11850353 0.98 ENSDART00000033361
ttyh3b
tweety family member 3b
chr3_-_59981476 0.96 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr2_-_49978227 0.95 ENSDART00000142835
hecw1b
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b
chr20_+_52774730 0.94 ENSDART00000014606
phactr1
phosphatase and actin regulator 1
chr8_+_47571211 0.94 ENSDART00000131460
plch2a
phospholipase C, eta 2a
chr25_-_23745765 0.90 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr15_+_1372343 0.90 ENSDART00000152285
schip1
schwannomin interacting protein 1
chr10_+_21576909 0.90 ENSDART00000168604
ENSDART00000166533
pcdh1a3
protocadherin 1 alpha 3
chr18_+_11506561 0.90 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr20_+_572037 0.87 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
smyd2b
SET and MYND domain containing 2b
chr10_+_39091353 0.82 ENSDART00000125986
si:ch73-1a9.4
si:ch73-1a9.4
chr22_-_20695237 0.81 ENSDART00000112722
org
oogenesis-related gene
chr8_-_18262149 0.80 ENSDART00000143000
rnf220b
ring finger protein 220b
chr9_+_52492639 0.78 ENSDART00000078939
march4
membrane-associated ring finger (C3HC4) 4
chr15_-_16679517 0.76 ENSDART00000177384
caln1
calneuron 1
chr8_-_36287046 0.76 ENSDART00000162877
si:busm1-194e12.11
si:busm1-194e12.11
chr13_-_32626247 0.74 ENSDART00000100663
wdr35
WD repeat domain 35
chr8_-_50888806 0.71 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr2_+_37430917 0.71 ENSDART00000140558
phc3
polyhomeotic homolog 3 (Drosophila)
chr14_-_2322484 0.69 ENSDART00000167806
si:ch73-379j16.2
si:ch73-379j16.2
chr7_-_27685365 0.69 ENSDART00000188342
calca
calcitonin/calcitonin-related polypeptide, alpha
chr1_-_14332283 0.68 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr21_-_35325466 0.68 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr14_+_6159162 0.68 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr19_-_47570672 0.67 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr1_-_20273227 0.66 ENSDART00000146084
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr11_-_38083397 0.64 ENSDART00000086516
ENSDART00000184033
klhdc8a
kelch domain containing 8A
chr7_+_3357973 0.63 ENSDART00000172853
si:ch211-285c6.5
si:ch211-285c6.5
chr19_+_19600297 0.63 ENSDART00000160134
ENSDART00000183493
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr7_-_55648336 0.63 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr6_-_39489190 0.63 ENSDART00000151299
scn8ab
sodium channel, voltage gated, type VIII, alpha subunit b
chr19_+_712127 0.62 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr3_-_55404985 0.61 ENSDART00000154274
mafga
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
chr7_-_41964877 0.60 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neto2b
neuropilin (NRP) and tolloid (TLL)-like 2b
chr23_-_31506854 0.59 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
eya4
EYA transcriptional coactivator and phosphatase 4
chr11_+_18183220 0.56 ENSDART00000113468
LO018315.10

chr9_-_34937025 0.56 ENSDART00000137888
cdc16
cell division cycle 16 homolog (S. cerevisiae)
chr10_+_5025696 0.56 ENSDART00000031165
enoph1
enolase-phosphatase 1
chr16_-_23379464 0.56 ENSDART00000045891
trim46a
tripartite motif containing 46a
chr17_-_43558494 0.55 ENSDART00000103830
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr11_-_42980535 0.55 ENSDART00000181160
ENSDART00000192064
CABZ01069998.1

chr24_+_11106402 0.55 ENSDART00000146697
prlh2
prolactin releasing hormone 2
chr17_-_12966907 0.55 ENSDART00000022874
psma6a
proteasome subunit alpha 6a
chr21_+_22400951 0.53 ENSDART00000134592
lmbrd2b
LMBR1 domain containing 2b
chr4_-_10599062 0.52 ENSDART00000048003
tspan12
tetraspanin 12
chr4_-_20232974 0.52 ENSDART00000193353
stk38l
serine/threonine kinase 38 like
chr24_-_9300160 0.51 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr7_-_6604623 0.51 ENSDART00000172874
kcnj10a
potassium inwardly-rectifying channel, subfamily J, member 10a
chr11_+_43751263 0.50 ENSDART00000163843
zgc:153431
zgc:153431
chr8_+_43053519 0.50 ENSDART00000147178
prnpa
prion protein a
chr19_-_22568203 0.49 ENSDART00000182888
pleca
plectin a
chr23_+_32028574 0.48 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr15_-_47956388 0.48 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr18_+_1154189 0.47 ENSDART00000135090
si:ch1073-75f15.2
si:ch1073-75f15.2
chr2_-_33645411 0.46 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr11_-_16021424 0.46 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
zgc:173544
chr12_+_3078221 0.45 ENSDART00000148835
ENSDART00000149427
sgca
sarcoglycan, alpha
chr3_+_17346502 0.45 ENSDART00000187786
ENSDART00000131584
si:ch211-210g13.5
si:ch211-210g13.5
chr8_+_35212233 0.44 ENSDART00000111021
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr13_+_29771463 0.44 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
pax2a
paired box 2a
chr21_-_4922981 0.43 ENSDART00000191819
ENSDART00000113556
ENSDART00000193269
ENSDART00000182961
kcnt1
potassium channel, subfamily T, member 1
chr23_+_40109353 0.43 ENSDART00000149249
ghrhrl
growth hormone releasing hormone receptor, like
chr3_+_24595922 0.42 ENSDART00000169405
si:dkey-68o6.5
si:dkey-68o6.5
chr19_-_41052408 0.42 ENSDART00000151120
sgce
sarcoglycan, epsilon
chr17_+_6828550 0.41 ENSDART00000153777
si:ch73-242m19.1
si:ch73-242m19.1
chr21_+_35327589 0.40 ENSDART00000145191
ENSDART00000132743
rars
arginyl-tRNA synthetase
chr13_-_17729474 0.40 ENSDART00000013011
vdac2
voltage-dependent anion channel 2
chr2_+_13462305 0.40 ENSDART00000149309
ENSDART00000080900
cfap57
cilia and flagella associated protein 57
chr7_-_33961551 0.39 ENSDART00000100104
skor1a
SKI family transcriptional corepressor 1a
chr2_+_56657804 0.39 ENSDART00000113964
POLR2E (1 of many)
RNA polymerase II subunit E
chr15_-_15469079 0.39 ENSDART00000132637
ENSDART00000004220
rab34a
RAB34, member RAS oncogene family a
chr8_-_30779101 0.38 ENSDART00000062229
p2rx7
purinergic receptor P2X, ligand-gated ion channel, 7
chr21_-_2130241 0.38 ENSDART00000167648
ENSDART00000163781
si:rp71-1h20.5
si:rp71-1h20.5
chr10_+_44700103 0.37 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr4_+_22480169 0.37 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr7_-_47850702 0.36 ENSDART00000109511
si:ch211-186j3.6
si:ch211-186j3.6
chr5_+_59392183 0.36 ENSDART00000082983
ENSDART00000180882
clip2
CAP-GLY domain containing linker protein 2
chr4_-_2036620 0.36 ENSDART00000150490
si:dkey-97m3.1
si:dkey-97m3.1
chr2_+_6127593 0.36 ENSDART00000184007
fzr1b
fizzy/cell division cycle 20 related 1b
chr19_+_21919856 0.35 ENSDART00000187306
ENSDART00000138544
galr1a
galanin receptor 1a
chr1_-_44000940 0.34 ENSDART00000134932
ENSDART00000138447
zgc:66472
zgc:66472
chr17_-_43391499 0.34 ENSDART00000189280
itpk1b
inositol-tetrakisphosphate 1-kinase b
chr3_-_32898626 0.32 ENSDART00000103201
kat7a
K(lysine) acetyltransferase 7a
chr22_+_19366866 0.32 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr7_-_40630698 0.32 ENSDART00000134547
ube3c
ubiquitin protein ligase E3C
chr9_+_44721808 0.32 ENSDART00000190578
nckap1
NCK-associated protein 1
chr11_-_8782871 0.32 ENSDART00000158546
si:ch211-51h4.2
si:ch211-51h4.2
chr11_+_23810148 0.32 ENSDART00000127846
nfasca
neurofascin homolog (chicken) a
chr21_-_25668153 0.32 ENSDART00000192062
tmem179b
transmembrane protein 179B
chr5_-_20814576 0.31 ENSDART00000098682
ENSDART00000147639
si:ch211-225b11.1
si:ch211-225b11.1
chr23_-_16981899 0.31 ENSDART00000125472
ENSDART00000142297
ENSDART00000143180
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr13_-_12006007 0.31 ENSDART00000111438
mgea5
meningioma expressed antigen 5 (hyaluronidase)
chr21_+_45510448 0.30 ENSDART00000160494
ENSDART00000167914
fnip1
folliculin interacting protein 1
chr10_+_44699734 0.29 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr17_-_8656155 0.29 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr5_+_39537195 0.28 ENSDART00000051256
fgf5
fibroblast growth factor 5
chr21_-_2348838 0.28 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr5_+_31791001 0.28 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr24_-_31123365 0.27 ENSDART00000182947
tmem56a
transmembrane protein 56a
chr11_+_25257022 0.27 ENSDART00000156052
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr1_-_10647307 0.26 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr11_-_3613558 0.26 ENSDART00000163578
dnajc16l
DnaJ (Hsp40) homolog, subfamily C, member 16 like
chr5_+_31283576 0.26 ENSDART00000133743
camkk1a
calcium/calmodulin-dependent protein kinase kinase 1, alpha a
chr13_-_37383625 0.25 ENSDART00000192888
ENSDART00000100322
ENSDART00000138934
kcnh5b
potassium voltage-gated channel, subfamily H (eag-related), member 5b
chr10_+_16069987 0.25 ENSDART00000043936
megf10
multiple EGF-like-domains 10
chr7_+_38809241 0.24 ENSDART00000190979
harbi1
harbinger transposase derived 1
chr22_+_1700552 0.24 ENSDART00000166185
znf1154
zinc finger protein 1154
chr24_-_21404367 0.23 ENSDART00000152093
atp8a2
ATPase phospholipid transporting 8A2
chr10_-_1961576 0.23 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr9_-_1459985 0.23 ENSDART00000124777
osbpl6
oxysterol binding protein-like 6
chr18_+_41313999 0.23 ENSDART00000048985
veph1
ventricular zone expressed PH domain-containing 1
chr15_-_25613114 0.23 ENSDART00000182431
ENSDART00000187405
taok1a
TAO kinase 1a
chr25_-_10622449 0.22 ENSDART00000155375
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr25_-_24233884 0.22 ENSDART00000146419
si:dkey-11e23.9
si:dkey-11e23.9
chr15_+_897280 0.21 ENSDART00000155470
znf1012
zinc finger protein 1012
chr7_+_6480212 0.21 ENSDART00000173320
si:cabz01036022.1
si:cabz01036022.1
chr15_-_1844048 0.21 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_+_38913621 0.20 ENSDART00000137112
fras1
Fraser extracellular matrix complex subunit 1
chr15_+_38887467 0.20 ENSDART00000185222
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr9_-_12269847 0.20 ENSDART00000136558
ENSDART00000144734
ENSDART00000131766
ENSDART00000032344
nup35
nucleoporin 35
chr1_-_45614481 0.20 ENSDART00000148413
atf7ip
activating transcription factor 7 interacting protein
chr5_+_66433287 0.20 ENSDART00000170757
kntc1
kinetochore associated 1
chr3_-_18410968 0.19 ENSDART00000041842
ndufb10
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr5_-_67783593 0.19 ENSDART00000010934
casr
calcium-sensing receptor
chr2_+_5300405 0.19 ENSDART00000019925
GNB4
G protein subunit beta 4
chr24_+_35981471 0.19 ENSDART00000157373
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr11_-_35575791 0.18 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema3fb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr6_-_9236309 0.18 ENSDART00000160397
ENSDART00000164603
iqcb1
IQ motif containing B1
chr14_-_38826739 0.18 ENSDART00000187633
spdl1
spindle apparatus coiled-coil protein 1
chr22_+_37631234 0.18 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr25_-_3627130 0.18 ENSDART00000171863
si:ch211-272n13.3
si:ch211-272n13.3
chr22_+_1462177 0.17 ENSDART00000164685
si:dkeyp-53d3.5
si:dkeyp-53d3.5
chr15_-_23692359 0.17 ENSDART00000141618
ercc2
excision repair cross-complementation group 2
chr21_-_44772738 0.16 ENSDART00000026178
kif4
kinesin family member 4
chr21_-_2299002 0.16 ENSDART00000168712
si:ch73-299h12.6
si:ch73-299h12.6
chr24_+_39277043 0.16 ENSDART00000165458
MPRIP
si:ch73-103b11.2
chr14_-_16151055 0.16 ENSDART00000162431
ptcd3
pentatricopeptide repeat domain 3
chr15_+_23799461 0.16 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr4_-_65037243 0.16 ENSDART00000170059
si:ch211-283l16.1
si:ch211-283l16.1
chr21_-_2952789 0.16 ENSDART00000182898
znf971
zinc finger protein 971
chr14_-_10762629 0.15 ENSDART00000061928
fgf16
fibroblast growth factor 16
chr16_-_41059919 0.14 ENSDART00000188803
si:dkey-201i6.8
si:dkey-201i6.8
chr12_-_31461412 0.13 ENSDART00000175929
ENSDART00000186342
acsl5
acyl-CoA synthetase long chain family member 5
chr1_-_11973341 0.13 ENSDART00000159981
ENSDART00000066638
grk4
G protein-coupled receptor kinase 4
chr13_-_12005429 0.13 ENSDART00000180302
mgea5
meningioma expressed antigen 5 (hyaluronidase)
chr14_-_33859149 0.13 ENSDART00000163877
ocrl
oculocerebrorenal syndrome of Lowe
chr8_-_11146687 0.13 ENSDART00000189626
asb13b
ankyrin repeat and SOCS box containing 13b
chr25_+_20694177 0.12 ENSDART00000073648
kxd1
KxDL motif containing 1
chr9_-_746317 0.12 ENSDART00000129632
ENSDART00000130720
usp37
ubiquitin specific peptidase 37
chr7_+_34290051 0.12 ENSDART00000123498
fibinb
fin bud initiation factor b
chr18_+_30370339 0.11 ENSDART00000158871
gse1
Gse1 coiled-coil protein
chr23_-_6765653 0.11 ENSDART00000192310
FP102169.1

chr7_-_24149670 0.11 ENSDART00000005884
mmp14a
matrix metallopeptidase 14a (membrane-inserted)
chr17_-_200316 0.10 ENSDART00000190561
CABZ01083778.1

chr22_+_17784414 0.09 ENSDART00000188189
ENSDART00000145260
tm6sf2
transmembrane 6 superfamily member 2
chr2_-_38204845 0.09 ENSDART00000142342
acin1a
apoptotic chromatin condensation inducer 1a
chr2_-_1468258 0.09 ENSDART00000114431
gpaa1
glycosylphosphatidylinositol anchor attachment 1
chr3_+_27606505 0.09 ENSDART00000150953
usp7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr21_-_25618175 0.09 ENSDART00000133512
fosl1b
FOS-like antigen 1b
chr2_+_31597841 0.09 ENSDART00000162181
si:ch211-106h4.4
si:ch211-106h4.4
chr16_-_25085327 0.08 ENSDART00000077661
prss1
protease, serine 1
chr2_+_32846602 0.08 ENSDART00000056649
tmem53
transmembrane protein 53
chr22_+_2844865 0.08 ENSDART00000139123
si:dkey-20i20.4
si:dkey-20i20.4
chr13_-_8601184 0.08 ENSDART00000045086
prkceb
protein kinase C, epsilon b
chr16_-_2390931 0.08 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr7_+_23577723 0.08 ENSDART00000049885
si:dkey-172j4.3
si:dkey-172j4.3
chr16_-_48074540 0.07 ENSDART00000187258
ENSDART00000186694
CSMD3 (1 of many)
si:ch211-236p22.1
chr4_+_57099307 0.07 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr7_-_25930594 0.06 ENSDART00000192834
BX005022.1

chr2_+_32826235 0.06 ENSDART00000143127
si:dkey-154p10.3
si:dkey-154p10.3
chr2_-_43942595 0.06 ENSDART00000147925
si:ch211-195h23.4
si:ch211-195h23.4
chr17_+_50248152 0.06 ENSDART00000153998
zc2hc1c
zinc finger, C2HC-type containing 1C
chr6_-_2134581 0.06 ENSDART00000175478
vstm2l
V-set and transmembrane domain containing 2 like
chr2_+_37897079 0.06 ENSDART00000141784
tep1
telomerase-associated protein 1
chr17_-_22324727 0.06 ENSDART00000160341
CU104709.1

chr3_-_30388525 0.06 ENSDART00000183790
lrrc4ba
leucine rich repeat containing 4Ba
chr2_-_37803614 0.05 ENSDART00000154124
nfatc4
nuclear factor of activated T cells 4
chr19_+_11432330 0.05 ENSDART00000188065
PQLC1
PQ loop repeat containing 1
chr9_-_30220818 0.05 ENSDART00000140929
si:dkey-100n23.3
si:dkey-100n23.3
chr8_-_42594380 0.05 ENSDART00000140126
ENSDART00000135238
ENSDART00000192764
dok2
docking protein 2
chr19_-_11248982 0.04 ENSDART00000091237
irgf3
immunity-related GTPase family, f3
chr20_-_23041275 0.04 ENSDART00000188200
BX511028.1

chr23_-_46034609 0.04 ENSDART00000158712
zgc:65873
zgc:65873
chr8_-_4892913 0.04 ENSDART00000126808
igsf9b
immunoglobulin superfamily, member 9b
chr16_+_23531583 0.03 ENSDART00000146708
adar
adenosine deaminase, RNA-specific
chr19_-_47832853 0.03 ENSDART00000170988
ago4
argonaute RISC catalytic component 4

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 0.6 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.2 1.0 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 1.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.9 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 2.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0090008 hypoblast development(GO:0090008)
0.1 0.5 GO:0036268 swimming(GO:0036268)
0.1 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.6 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.4 GO:0021588 cerebellum formation(GO:0021588) anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.5 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 0.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 3.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:1902001 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.3 GO:0061550 cranial ganglion development(GO:0061550)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0036372 opsin transport(GO:0036372)
0.0 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.4 GO:0030800 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.0 0.2 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 1.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 1.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.5 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.2 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0019226 transmission of nerve impulse(GO:0019226)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.6 GO:1990246 uniplex complex(GO:1990246)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.6 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031716 calcitonin receptor binding(GO:0031716)
0.2 0.6 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.3 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.7 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 3.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.8 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor