Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for hoxb10a+hoxc10a

Z-value: 0.76

Motif logo

logo of

Transcription factors associated with hoxb10a+hoxc10a

Gene Symbol Gene ID Gene Info
hoxb10a
ENSDARG00000011579 homeobox B10a
hoxc10a
ENSDARG00000070348 homeobox C10a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb10adr11_v1_chr3_+_23669267_23669267-0.214.3e-02Click!
hoxc10adr11_v1_chr23_+_36083529_36083617-0.205.1e-02Click!

Activity profile of hoxb10a+hoxc10a motif

Sorted Z-values of hoxb10a+hoxc10a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_20373058 8.35 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr1_-_38195012 7.37 ENSDART00000020409
hand2
heart and neural crest derivatives expressed 2
chr6_-_30485009 7.02 ENSDART00000025698
zgc:153311
zgc:153311
chr20_+_26538137 6.73 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr6_+_36877968 6.32 ENSDART00000155187
traf3ip2l
TRAF3 interacting protein 2-like
chr14_+_30279391 6.26 ENSDART00000172794
fgl1
fibrinogen-like 1
chr8_+_3379815 5.87 ENSDART00000155995
FUT9 (1 of many)
zgc:136963
chr24_-_27473771 5.49 ENSDART00000139874
cxl34b.11
CX chemokine ligand 34b, duplicate 11
chr10_+_26612321 5.13 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr23_+_39606108 4.91 ENSDART00000109464
g0s2
G0/G1 switch 2
chr24_-_27452488 4.77 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr5_+_15202495 4.76 ENSDART00000144915
tbx1
T-box 1
chr23_+_10146542 4.73 ENSDART00000048073
zgc:171775
zgc:171775
chr4_+_7391110 4.66 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr13_-_12660318 4.58 ENSDART00000008498
adh8a
alcohol dehydrogenase 8a
chr21_-_25756119 4.50 ENSDART00000002341
cldnc
claudin c
chr17_+_27456804 4.27 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr7_+_48761875 4.12 ENSDART00000003690
acana
aggrecan a
chr25_+_4750972 3.98 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr4_+_7391400 3.90 ENSDART00000169111
ENSDART00000186395
tnni4a
troponin I4a
chr19_+_2590182 3.87 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr16_-_45917322 3.69 ENSDART00000060822
afp4
antifreeze protein type IV
chr19_+_19762183 3.66 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr11_-_6265574 3.49 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr12_-_22400999 3.48 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr7_+_22688781 3.45 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr5_-_24174956 3.39 ENSDART00000137631
si:ch211-137i24.10
si:ch211-137i24.10
chr17_+_45395846 3.38 ENSDART00000058793
nenf
neudesin neurotrophic factor
chr23_+_17417539 3.38 ENSDART00000182605
BX649300.2

chr19_-_15855427 3.37 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr21_-_2415808 3.36 ENSDART00000171179
si:ch211-241b2.5
si:ch211-241b2.5
chr20_-_32045057 3.35 ENSDART00000152970
ENSDART00000034248
rab32a
RAB32a, member RAS oncogene family
chr13_-_50108337 3.35 ENSDART00000133308
nid1a
nidogen 1a
chr16_-_21038015 3.28 ENSDART00000059239
snx10b
sorting nexin 10b
chr5_-_26181863 3.28 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr13_-_42749916 3.04 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr6_+_13045885 2.99 ENSDART00000104757
casp8
caspase 8, apoptosis-related cysteine peptidase
chr19_-_47571456 2.96 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr16_-_7443388 2.85 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr24_-_27461295 2.81 ENSDART00000110748
ccl34b.9
chemokine (C-C motif) ligand 34b, duplicate 9
chr7_-_16562200 2.79 ENSDART00000169093
ENSDART00000173491
csrp3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr15_-_4580763 2.75 ENSDART00000008170
rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr13_-_35984530 2.74 ENSDART00000143488
si:ch211-67f13.8
si:ch211-67f13.8
chr23_+_7379728 2.73 ENSDART00000012194
gata5
GATA binding protein 5
chr1_-_37377509 2.65 ENSDART00000113542
tnip2
TNFAIP3 interacting protein 2
chr23_+_24085531 2.56 ENSDART00000139710
ttll10
tubulin tyrosine ligase-like family, member 10
chr12_+_46543572 2.55 ENSDART00000167510
hid1b
HID1 domain containing b
chr1_+_1915967 2.54 ENSDART00000131463
si:ch211-132g1.1
si:ch211-132g1.1
chr5_-_57723929 2.52 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr24_+_12913329 2.44 ENSDART00000141829
si:dkeyp-28d2.4
si:dkeyp-28d2.4
chr16_+_50969248 2.33 ENSDART00000172068
si:dkeyp-97a10.2
si:dkeyp-97a10.2
chr16_+_25535993 2.29 ENSDART00000077436
mylipb
myosin regulatory light chain interacting protein b
chr20_+_6543674 2.07 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr14_-_31488100 2.00 ENSDART00000186246
cab39l1
calcium binding protein 39, like 1
chr6_+_27624023 1.98 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr17_+_33453689 1.98 ENSDART00000156894
rin3
Ras and Rab interactor 3
chr19_+_17385561 1.95 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
rpl15
ribosomal protein L15
chr7_+_34296789 1.90 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr18_-_17513426 1.87 ENSDART00000146725
b3gnt9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr3_+_35812040 1.86 ENSDART00000075903
ENSDART00000147712
crlf3
cytokine receptor-like factor 3
chr10_+_36650222 1.85 ENSDART00000126963
ucp3
uncoupling protein 3
chr7_-_60096318 1.80 ENSDART00000189125
BX511067.1

chr11_-_18253111 1.80 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr20_+_52546186 1.80 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr7_+_60111581 1.78 ENSDART00000087093
hspa12b
heat shock protein 12B
chr25_+_29474982 1.77 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr8_+_2487250 1.76 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr13_+_24584401 1.71 ENSDART00000057599
fuom
fucose mutarotase
chr6_+_41191482 1.69 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr3_+_46764278 1.69 ENSDART00000136051
ENSDART00000164930
prkcsh
protein kinase C substrate 80K-H
chr20_-_29499363 1.68 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr20_-_33961697 1.67 ENSDART00000061765
selp
selectin P
chr16_+_25664387 1.59 ENSDART00000184394
nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr19_+_19761966 1.57 ENSDART00000163697
hoxa3a
homeobox A3a
chr6_-_28222592 1.54 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr8_-_19487327 1.54 ENSDART00000111710
edem3
ER degradation enhancer, mannosidase alpha-like 3
chr7_+_58179513 1.54 ENSDART00000123117
ggh
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr23_-_43718067 1.52 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr4_-_14191717 1.52 ENSDART00000147928
pus7l
pseudouridylate synthase 7-like
chr20_-_33966148 1.51 ENSDART00000148111
selp
selectin P
chr10_+_2587234 1.48 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr4_+_51552434 1.47 ENSDART00000165016
si:dkey-165e24.1
si:dkey-165e24.1
chr16_+_25664078 1.47 ENSDART00000154024
nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr7_+_24165371 1.45 ENSDART00000173472
si:ch211-216p19.5
si:ch211-216p19.5
chr20_-_25533739 1.44 ENSDART00000063064
cyp2ad6
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr5_-_36597612 1.43 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr6_+_30703828 1.42 ENSDART00000104628
insl5a
insulin-like 5a
chr2_-_55298075 1.40 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr4_-_14191434 1.39 ENSDART00000142374
ENSDART00000136730
pus7l
pseudouridylate synthase 7-like
chr10_-_35002731 1.37 ENSDART00000131279
alg5
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
chr16_-_41646164 1.36 ENSDART00000184257
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr18_-_15329454 1.32 ENSDART00000191903
ENSDART00000019818
ric8b
RIC8 guanine nucleotide exchange factor B
chr23_+_25354856 1.31 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3
chr2_-_6039757 1.31 ENSDART00000013079
scp2a
sterol carrier protein 2a
chr11_+_14284866 1.26 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr21_-_32781612 1.20 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr1_-_9249943 1.19 ENSDART00000055011
zgc:136472
zgc:136472
chr10_+_5234327 1.18 ENSDART00000133927
ENSDART00000063120
sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr5_-_54712159 1.16 ENSDART00000149207
ccnb1
cyclin B1
chr17_+_17764979 1.15 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr18_+_41232719 1.14 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr13_-_26799244 1.11 ENSDART00000036419
vrk2
vaccinia related kinase 2
chr2_-_28420415 1.10 ENSDART00000183857
CABZ01056051.1

chr19_-_47571797 1.06 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr19_+_28187480 1.01 ENSDART00000183825
irx4b
iroquois homeobox 4b
chr4_-_14192254 0.99 ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr2_+_52847049 0.97 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr14_+_23717165 0.96 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr14_+_21159693 0.95 ENSDART00000192678
zgc:136929
zgc:136929
chr1_-_35924495 0.94 ENSDART00000184424
smad1
SMAD family member 1
chr2_-_35566938 0.91 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tnn
tenascin N
chr23_+_27068225 0.91 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr1_+_51407520 0.89 ENSDART00000074294
actr2a
ARP2 actin related protein 2a homolog
chr17_+_47090497 0.87 ENSDART00000169038
ENSDART00000159292
zgc:103755
zgc:103755
chr25_-_31898552 0.87 ENSDART00000156128
si:ch73-330k17.3
si:ch73-330k17.3
chr11_+_36683859 0.85 ENSDART00000170102
si:ch211-11c3.12
si:ch211-11c3.12
chr4_-_56898328 0.85 ENSDART00000169189
si:dkey-269o24.6
si:dkey-269o24.6
chr10_+_44692272 0.83 ENSDART00000157458
ubc
ubiquitin C
chr12_-_13155653 0.82 ENSDART00000152467
cxl34c
CX chemokine ligand 34c
chr22_-_4644484 0.81 ENSDART00000167748
fbn2b
fibrillin 2b
chr25_-_13614863 0.77 ENSDART00000121859
fa2h
fatty acid 2-hydroxylase
chr23_+_43718115 0.76 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr25_+_20089986 0.76 ENSDART00000143441
ENSDART00000184073
tnni4b.2
troponin I4b, tandem duplicate 2
chr9_+_38588081 0.75 ENSDART00000031127
ENSDART00000131784
snx4
sorting nexin 4
chr2_-_38287987 0.74 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr21_-_14826066 0.72 ENSDART00000067001
noc4l
nucleolar complex associated 4 homolog
chr4_+_2267641 0.70 ENSDART00000165503
si:ch73-89b15.3
si:ch73-89b15.3
chr5_-_23715861 0.70 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr15_-_1843831 0.70 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_+_19191787 0.69 ENSDART00000152892
slc16a8
solute carrier family 16 (monocarboxylate transporter), member 8
chr2_+_35595454 0.67 ENSDART00000098734
cacybp
calcyclin binding protein
chr8_+_2487883 0.67 ENSDART00000101841
dynll1
dynein, light chain, LC8-type 1
chr6_+_13083146 0.65 ENSDART00000172158
l3hypdh
trans-L-3-hydroxyproline dehydratase
chr6_+_35362225 0.65 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr20_+_16173618 0.64 ENSDART00000192109
ENSDART00000104112
ENSDART00000129633
zyg11
zyg-11 homolog (C. elegans)
chr16_+_13883872 0.63 ENSDART00000101304
ENSDART00000136005
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr13_-_50546634 0.62 ENSDART00000192127
CU570781.2

chr5_-_42883761 0.61 ENSDART00000167374
BX323596.2

chr13_+_45431660 0.60 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr19_+_7759354 0.57 ENSDART00000151400
ubap2l
ubiquitin associated protein 2-like
chr7_-_41338923 0.55 ENSDART00000099138
ncf2
neutrophil cytosolic factor 2
chr2_+_24374305 0.53 ENSDART00000022379
nr2f6a
nuclear receptor subfamily 2, group F, member 6a
chr3_-_31069776 0.52 ENSDART00000167462
elob
elongin B
chr23_-_9807546 0.51 ENSDART00000136740
ENSDART00000004474
mapre1b
microtubule-associated protein, RP/EB family, member 1b
chr12_-_13337033 0.51 ENSDART00000105903
ENSDART00000139786
lsm5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr20_-_51186524 0.51 ENSDART00000027836
ENSDART00000114407
rbm25b
RNA binding motif protein 25b
chr13_-_37519774 0.51 ENSDART00000141420
ENSDART00000185478
sgpp1
sphingosine-1-phosphate phosphatase 1
chr1_+_2301961 0.51 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_-_47090440 0.48 ENSDART00000163542
CABZ01056321.1

chr3_+_32933663 0.47 ENSDART00000112742
nbr1b
neighbor of brca1 gene 1b
chr8_+_18588551 0.47 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr7_+_27317174 0.45 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr24_+_1042594 0.44 ENSDART00000109117
si:dkey-192l18.9
si:dkey-192l18.9
chr13_+_9612395 0.44 ENSDART00000136689
ENSDART00000138362
slf2
SMC5-SMC6 complex localization factor 2
chr20_+_9763364 0.43 ENSDART00000053834
psmc6
proteasome 26S subunit, ATPase 6
chr15_-_28860282 0.41 ENSDART00000156738
gpr4
G protein-coupled receptor 4
chr21_-_26520629 0.41 ENSDART00000142731
rce1b
Ras converting CAAX endopeptidase 1b
chr14_-_33613794 0.40 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr5_+_30588856 0.40 ENSDART00000086661
dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr6_-_37749711 0.38 ENSDART00000078324
nipa1
non imprinted in Prader-Willi/Angelman syndrome 1
chr13_+_22295905 0.37 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr8_+_30709685 0.35 ENSDART00000133989
upb1
ureidopropionase, beta
chr19_-_10881486 0.35 ENSDART00000168852
ENSDART00000160438
PSMD4 (1 of many)
psmd4a
proteasome 26S subunit, non-ATPase 4
proteasome 26S subunit, non-ATPase 4a
chr24_-_12689571 0.35 ENSDART00000015517
pdcd6
programmed cell death 6
chr23_-_24047054 0.35 ENSDART00000184308
ENSDART00000185902
CR925720.1

chr17_+_47116500 0.32 ENSDART00000186627
CLIP4
si:dkeyp-47f9.4
chr12_+_31638045 0.32 ENSDART00000184216
ENSDART00000183645
ENSDART00000153129
dnmbp
dynamin binding protein
chr17_-_2690083 0.31 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr19_-_22843480 0.31 ENSDART00000052503
nudcd1
NudC domain containing 1
chr12_-_26430507 0.30 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr21_+_20396858 0.30 ENSDART00000003299
ENSDART00000146615
zgc:103482
zgc:103482
chr21_-_27251112 0.30 ENSDART00000137667
mark2a
MAP/microtubule affinity-regulating kinase 2a
chr12_+_34051848 0.29 ENSDART00000153276
cyth1b
cytohesin 1b
chr11_-_24016761 0.28 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chia.3
chitinase, acidic.3
chr3_-_32873641 0.28 ENSDART00000075277
zgc:113090
zgc:113090
chr7_-_69025306 0.25 ENSDART00000180796
CABZ01057488.2

chr6_-_39653972 0.24 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr2_-_45663945 0.24 ENSDART00000075080
prpf38b
pre-mRNA processing factor 38B
chr4_+_44954486 0.23 ENSDART00000150875
si:dkeyp-100h4.8
si:dkeyp-100h4.8
chr10_-_2713228 0.23 ENSDART00000123754
ENSDART00000126236
mier3a
mesoderm induction early response 1, family member 3 a
chr5_-_50371205 0.22 ENSDART00000157800
si:ch73-280o22.2
si:ch73-280o22.2
chr12_-_19091214 0.22 ENSDART00000153225
si:ch73-139e5.4
si:ch73-139e5.4
chr6_-_12588044 0.21 ENSDART00000047896
slc15a1b
solute carrier family 15 (oligopeptide transporter), member 1b
chr21_+_4313039 0.21 ENSDART00000141146
HTRA2 (1 of many)
si:dkey-84o3.4
chr22_+_1779401 0.20 ENSDART00000170126
znf1154
zinc finger protein 1154
chr18_+_7363242 0.16 ENSDART00000133375
si:dkey-30c15.17
si:dkey-30c15.17
chr9_-_1939232 0.16 ENSDART00000146131
hoxd3a
homeobox D3a
chr1_-_39983730 0.16 ENSDART00000160066
ing2
inhibitor of growth family, member 2
chr14_-_30967284 0.15 ENSDART00000149435
il2rgb
interleukin 2 receptor, gamma b
chr22_-_8594846 0.15 ENSDART00000081690
ENSDART00000192241
si:ch73-27e22.1
si:ch73-27e22.1
chr10_-_10969444 0.14 ENSDART00000138041
exd3
exonuclease 3'-5' domain containing 3
chr16_+_39271123 0.13 ENSDART00000043823
ENSDART00000141801
osbpl10b
oxysterol binding protein-like 10b
chr5_-_57289872 0.12 ENSDART00000189893
ENSDART00000050957
fer
fer (fps/fes related) tyrosine kinase
chr15_-_5212930 0.11 ENSDART00000136845
or128-6
odorant receptor, family E, subfamily 128, member 6
chr14_+_23593989 0.11 ENSDART00000163682
med12
mediator complex subunit 12
chr7_-_29341233 0.10 ENSDART00000140938
ENSDART00000147251
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr8_+_8860902 0.10 ENSDART00000144986
otud5a
OTU deubiquitinase 5a
chr1_+_40801448 0.10 ENSDART00000187394
cpz
carboxypeptidase Z
chr12_+_17603528 0.10 ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr5_+_24245682 0.09 ENSDART00000049003
atp6v1aa
ATPase H+ transporting V1 subunit Aa

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb10a+hoxc10a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0003156 regulation of organ formation(GO:0003156)
1.2 7.4 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
1.2 3.5 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
1.0 3.0 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.9 2.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.7 5.2 GO:0060017 parathyroid gland development(GO:0060017)
0.7 2.8 GO:0035994 response to muscle stretch(GO:0035994)
0.7 4.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.7 2.7 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.7 4.6 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.5 3.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.5 5.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 2.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.4 2.8 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 1.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 3.4 GO:0060036 notochord cell vacuolation(GO:0060036)
0.4 1.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.4 1.4 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.3 3.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.3 1.7 GO:0006004 fucose metabolic process(GO:0006004)
0.3 1.4 GO:0055071 manganese ion homeostasis(GO:0055071)
0.3 1.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 0.8 GO:2000136 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.3 1.3 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.3 3.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 1.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.2 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.2 5.1 GO:1990798 pancreas regeneration(GO:1990798)
0.2 2.0 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.2 6.3 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.2 3.3 GO:0042693 muscle cell fate commitment(GO:0042693)
0.2 1.1 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 1.3 GO:0070285 pigment cell development(GO:0070285)
0.2 9.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 7.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 3.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 1.5 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 1.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.7 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.9 GO:0006833 water transport(GO:0006833)
0.1 1.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 3.7 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.9 GO:2001032 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 3.1 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 6.7 GO:0048278 vesicle docking(GO:0048278)
0.1 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.7 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.5 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 4.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.4 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 2.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.4 GO:1902622 Rac protein signal transduction(GO:0016601) regulation of neutrophil migration(GO:1902622)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 4.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 1.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 1.0 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 2.3 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 10.6 GO:0006955 immune response(GO:0006955)
0.0 0.9 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.2 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 1.0 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 3.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 1.7 GO:0017177 glucosidase II complex(GO:0017177)
0.4 1.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.3 6.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 1.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.7 GO:0030689 Noc complex(GO:0030689)
0.2 9.3 GO:0005861 troponin complex(GO:0005861)
0.2 2.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 3.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 5.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.4 GO:0005604 basement membrane(GO:0005604)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 6.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 31.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.3 GO:0015250 water channel activity(GO:0015250)
0.9 4.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.8 5.7 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 1.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 1.7 GO:0042806 fucose binding(GO:0042806)
0.5 1.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 7.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.3 1.2 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.2 0.7 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.2 3.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 3.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 9.8 GO:0008009 chemokine activity(GO:0008009)
0.2 3.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 1.0 GO:0050699 WW domain binding(GO:0050699)
0.2 2.5 GO:0016408 C-acyltransferase activity(GO:0016408)
0.2 2.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.5 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 2.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 4.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.8 GO:0042805 actinin binding(GO:0042805)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 3.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 5.1 GO:0044325 ion channel binding(GO:0044325)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.5 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 3.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 2.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.7 GO:0032190 acrosin binding(GO:0032190)
0.0 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 4.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 3.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0043130 ubiquitin binding(GO:0043130)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 4.9 PID E2F PATHWAY E2F transcription factor network
0.1 2.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 5.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 5.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 2.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 3.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 5.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 3.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C