PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
hoxb6a Links NCBI UniProt	ENSDARG00000010630	homeobox B6a
hoxb6b Links NCBI UniProt	ENSDARG00000026513	homeobox B6b
hoxb6b Links NCBI UniProt	ENSDARG00000111786	homeobox B6b

Gene	Promoter	Pearson corr. coef.	P-value	Plot
hoxb6b	dr11_v1_chr12_+_27127139_27127139	0.51	1.1e-07	Click!
hoxb6a	dr11_v1_chr3_+_23703704_23703704	0.23	2.4e-02	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_25916530 Show fit	78.82	ENSDART00000186386	sncgb Links NCBI UniProt Show fit	synuclein, gamma b (breast cancer-specific protein 1)
chr8_-_49431939 Show fit	75.54	ENSDART00000011453 ENSDART00000088240 ENSDART00000114173	sypb Links NCBI UniProt Show fit	synaptophysin b
chr9_-_32753535 Show fit	68.04	ENSDART00000060006	olig2 Links NCBI UniProt Show fit	oligodendrocyte lineage transcription factor 2
chr20_+_34915945 Show fit	66.28	ENSDART00000153064	snap25a Links NCBI UniProt Show fit	synaptosomal-associated protein, 25a
chr2_-_54387550 Show fit	62.83	ENSDART00000097388	napgb Links NCBI UniProt Show fit	N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr10_-_17745345 Show fit	61.74	ENSDART00000132690 ENSDART00000135376	si:dkey-200l5.4 Links NCBI UniProt Show fit	si:dkey-200l5.4
chr21_-_21373242 Show fit	57.87	ENSDART00000079629	ppm1nb Links NCBI UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr22_-_13851297 Show fit	57.34	ENSDART00000080306	s100b Links NCBI UniProt Show fit	S100 calcium binding protein, beta (neural)
chr4_-_7212875 Show fit	57.06	ENSDART00000161297	lrrn3b Links NCBI UniProt Show fit	leucine rich repeat neuronal 3b
chr5_-_29643930 Show fit	56.90	ENSDART00000161250	grin1b Links NCBI UniProt Show fit	glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr14_+_35748385 Show fit	56.73	ENSDART00000064617 ENSDART00000074671 ENSDART00000172803	gria2b Links NCBI UniProt Show fit	glutamate receptor, ionotropic, AMPA 2b
chr21_-_22114625 Show fit	54.81	ENSDART00000177426 ENSDART00000135410	elmod1 Links NCBI UniProt Show fit	ELMO/CED-12 domain containing 1
chr11_+_25735478 Show fit	53.79	ENSDART00000103566	si:dkey-183j2.10 Links NCBI UniProt Show fit	si:dkey-183j2.10
chr9_+_31282161 Show fit	52.33	ENSDART00000010774	zic2a Links NCBI UniProt Show fit	zic family member 2 (odd-paired homolog, Drosophila), a
chr21_-_22115136 Show fit	51.58	ENSDART00000134715 ENSDART00000089246 ENSDART00000139789	elmod1 Links NCBI UniProt Show fit	ELMO/CED-12 domain containing 1
chr24_-_6158933 Show fit	50.73	ENSDART00000021609	gad2 Links NCBI UniProt Show fit	glutamate decarboxylase 2
chr5_+_58372164 Show fit	50.73	ENSDART00000057910	nrgna Links NCBI UniProt Show fit	neurogranin (protein kinase C substrate, RC3) a
chr21_+_13861589 Show fit	48.99	ENSDART00000015629 ENSDART00000171306	stxbp1a Links NCBI UniProt Show fit	syntaxin binding protein 1a
chr22_+_18389271 Show fit	47.99	ENSDART00000088270	yjefn3 Links NCBI UniProt Show fit	YjeF N-terminal domain containing 3
chr14_+_35748206 Show fit	47.63	ENSDART00000177391	gria2b Links NCBI UniProt Show fit	glutamate receptor, ionotropic, AMPA 2b
chr16_-_16182319 Show fit	47.48	ENSDART00000103815	stmn2a Links NCBI UniProt Show fit	stathmin 2a
chr23_-_11870962 Show fit	47.42	ENSDART00000143481	si:dkey-178k16.1 Links NCBI UniProt Show fit	si:dkey-178k16.1
chr9_-_44295071 Show fit	47.35	ENSDART00000011837	neurod1 Links NCBI UniProt Show fit	neuronal differentiation 1
chr13_+_36764715 Show fit	46.30	ENSDART00000111832 ENSDART00000085230	atl1 Links NCBI UniProt Show fit	atlastin GTPase 1
chr4_+_5506952 Show fit	46.06	ENSDART00000032857 ENSDART00000160222	mapk11 Links NCBI UniProt Show fit	mitogen-activated protein kinase 11
chr23_-_30431333 Show fit	45.79	ENSDART00000146633	camta1a Links NCBI UniProt Show fit	calmodulin binding transcription activator 1a
chr10_+_21804772 Show fit	45.35	ENSDART00000162194	pcdh1g31 Links NCBI UniProt Show fit	protocadherin 1 gamma 31
chr20_-_34801181 Show fit	45.32	ENSDART00000048375 ENSDART00000132426	stmn4 Links NCBI UniProt Show fit	stathmin-like 4
chr4_+_12615836 Show fit	44.84	ENSDART00000003583	lmo3 Links NCBI UniProt Show fit	LIM domain only 3
chr15_+_43166511 Show fit	44.64	ENSDART00000011737	flj13639 Links NCBI UniProt Show fit	flj13639
chr4_+_11375894 Show fit	44.24	ENSDART00000190471 ENSDART00000143963	pcloa Links NCBI UniProt Show fit	piccolo presynaptic cytomatrix protein a
chr14_+_34966598 Show fit	44.06	ENSDART00000004550	rnf145a Links NCBI UniProt Show fit	ring finger protein 145a
chr9_-_54840124 Show fit	44.01	ENSDART00000137214 ENSDART00000085693	gpm6bb Links NCBI UniProt Show fit	glycoprotein M6Bb
chr20_-_25671342 Show fit	43.91	ENSDART00000182775	si:dkeyp-117h8.2 Links NCBI UniProt Show fit	si:dkeyp-117h8.2
chr21_-_42007213 Show fit	43.82	ENSDART00000188804 ENSDART00000092821 ENSDART00000165743	gabrg2 Links NCBI UniProt Show fit	gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr13_+_11436130 Show fit	43.67	ENSDART00000169895	zbtb18 Links NCBI UniProt Show fit	zinc finger and BTB domain containing 18
chr15_-_44512461 Show fit	43.57	ENSDART00000155456	gria4a Links NCBI UniProt Show fit	glutamate receptor, ionotropic, AMPA 4a
chr17_-_16965809 Show fit	43.30	ENSDART00000153697	nrxn3a Links NCBI UniProt Show fit	neurexin 3a
chr8_+_31248917 Show fit	43.04	ENSDART00000112170	unm_hu7912 Links NCBI UniProt Show fit	un-named hu7912
chr1_-_14234076 Show fit	42.76	ENSDART00000040049	camk2d2 Links NCBI UniProt Show fit	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr17_-_26926577 Show fit	42.64	ENSDART00000050202	rcan3 Links NCBI UniProt Show fit	regulator of calcineurin 3
chr12_+_24344963 Show fit	42.01	ENSDART00000191648 ENSDART00000183180 ENSDART00000088178 ENSDART00000189696	nrxn1a Links NCBI UniProt Show fit	neurexin 1a
chr14_+_35806605 Show fit	41.91	ENSDART00000173093	gria2b Links NCBI UniProt Show fit	glutamate receptor, ionotropic, AMPA 2b
chr2_+_31833997 Show fit	41.76	ENSDART00000066788	epdr1 Links NCBI UniProt Show fit	ependymin related 1
chr14_-_36378494 Show fit	41.75	ENSDART00000058503	gpm6aa Links NCBI UniProt Show fit	glycoprotein M6Aa
chr19_-_9472893 Show fit	41.55	ENSDART00000045565 ENSDART00000137505	vamp1 Links NCBI UniProt Show fit	vesicle-associated membrane protein 1
chr21_+_28958471 Show fit	41.12	ENSDART00000144331 ENSDART00000005929	ppp3ca Links NCBI UniProt Show fit	protein phosphatase 3, catalytic subunit, alpha isozyme
chr6_-_10320676 Show fit	40.97	ENSDART00000151247	scn1lab Links NCBI UniProt Show fit	sodium channel, voltage-gated, type I like, alpha b
chr24_-_24849091 Show fit	40.68	ENSDART00000133649 ENSDART00000038290	crhb Links NCBI UniProt Show fit	corticotropin releasing hormone b
chr13_+_27314795 Show fit	40.59	ENSDART00000128726	eef1a1a Links NCBI UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1a
chr8_+_31119548 Show fit	40.36	ENSDART00000136578	syn1 Links NCBI UniProt Show fit	synapsin I
chr1_+_25801648 Show fit	39.98	ENSDART00000129471	gucy1b1 Links NCBI UniProt Show fit	guanylate cyclase 1 soluble subunit beta 1
chr5_+_64732036 Show fit	39.96	ENSDART00000073950	olfm1a Links NCBI UniProt Show fit	olfactomedin 1a
chr2_+_34967022 Show fit	39.60	ENSDART00000134926	astn1 Links NCBI UniProt Show fit	astrotactin 1
chr10_-_22845485 Show fit	39.51	ENSDART00000079454	vamp2 Links NCBI UniProt Show fit	vesicle-associated membrane protein 2
chr20_+_34717403 Show fit	39.39	ENSDART00000034252	pnocb Links NCBI UniProt Show fit	prepronociceptin b
chr7_-_49594995 Show fit	39.17	ENSDART00000174161 ENSDART00000109147	brsk2b Links NCBI UniProt Show fit	BR serine/threonine kinase 2b
chr20_+_27020201 Show fit	38.94	ENSDART00000126919 ENSDART00000016014	chga Links NCBI UniProt Show fit	chromogranin A
chr5_-_23362602 Show fit	38.82	ENSDART00000137120	gria3a Links NCBI UniProt Show fit	glutamate receptor, ionotropic, AMPA 3a
chr12_-_10300101 Show fit	38.71	ENSDART00000126428	mpp2b Links NCBI UniProt Show fit	membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr24_-_15648636 Show fit	38.42	ENSDART00000136200	cbln2b Links NCBI UniProt Show fit	cerebellin 2b precursor
chr23_+_20563779 Show fit	38.37	ENSDART00000146008	camkvl Links NCBI UniProt Show fit	CaM kinase-like vesicle-associated, like
chr25_-_13381854 Show fit	38.36	ENSDART00000164621 ENSDART00000169129	ndrg4 Links NCBI UniProt Show fit	NDRG family member 4
chr16_+_37582872 Show fit	38.33	ENSDART00000169331	adgrb1a Links NCBI UniProt Show fit	adhesion G protein-coupled receptor B1a
chr17_-_12389259 Show fit	38.31	ENSDART00000185724	snap25b Links NCBI UniProt Show fit	synaptosomal-associated protein, 25b
chr22_-_11493236 Show fit	38.18	ENSDART00000002691	tspan7b Links NCBI UniProt Show fit	tetraspanin 7b
chr8_-_34052019 Show fit	38.17	ENSDART00000040126 ENSDART00000159208 ENSDART00000048994 ENSDART00000098822	pbx3b Links NCBI UniProt Show fit	pre-B-cell leukemia homeobox 3b
chr18_-_38088099 Show fit	37.78	ENSDART00000146120	luzp2 Links NCBI UniProt Show fit	leucine zipper protein 2
chr6_+_3828560 Show fit	37.30	ENSDART00000185273 ENSDART00000179091	gad1b Links NCBI UniProt Show fit	glutamate decarboxylase 1b
chr24_-_33756003 Show fit	37.10	ENSDART00000079283	tmeff1b Links NCBI UniProt Show fit	transmembrane protein with EGF-like and two follistatin-like domains 1b
chr15_-_24869826 Show fit	37.08	ENSDART00000127047	tusc5a Links NCBI UniProt Show fit	tumor suppressor candidate 5a
chr15_+_22267847 Show fit	37.05	ENSDART00000110665	spa17 Links NCBI UniProt Show fit	sperm autoantigenic protein 17
chr16_-_12173554 Show fit	36.97	ENSDART00000110567 ENSDART00000155935	clstn3 Links NCBI UniProt Show fit	calsyntenin 3
chr11_+_35364445 Show fit	36.87	ENSDART00000125766	camkvb Links NCBI UniProt Show fit	CaM kinase-like vesicle-associated b
chr5_-_23280098 Show fit	36.80	ENSDART00000126540 ENSDART00000051533	plp1b Links NCBI UniProt Show fit	proteolipid protein 1b
chr7_-_45076131 Show fit	36.66	ENSDART00000110590	zgc:194678 Links NCBI UniProt Show fit	zgc:194678
chr3_-_28665291 Show fit	36.46	ENSDART00000151670	fbxl16 Links NCBI UniProt Show fit	F-box and leucine-rich repeat protein 16
chr7_+_25059845 Show fit	36.45	ENSDART00000077215	ppp2r5b Links NCBI UniProt Show fit	protein phosphatase 2, regulatory subunit B', beta
chr21_+_22630297 Show fit	36.44	ENSDART00000147175	si:dkeyp-69c1.7 Links NCBI UniProt Show fit	si:dkeyp-69c1.7
chr19_+_10396042 Show fit	36.19	ENSDART00000028048 ENSDART00000151735	necap1 Links NCBI UniProt Show fit	NECAP endocytosis associated 1
chr24_+_2519761 Show fit	35.82	ENSDART00000106619	nrn1a Links NCBI UniProt Show fit	neuritin 1a
chr13_+_27951688 Show fit	35.68	ENSDART00000050303	b3gat2 Links NCBI UniProt Show fit	beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr13_-_29420885 Show fit	35.63	ENSDART00000024225	chata Links NCBI UniProt Show fit	choline O-acetyltransferase a
chr16_-_26074529 Show fit	35.56	ENSDART00000148653 ENSDART00000148923	tmem145 Links NCBI UniProt Show fit	transmembrane protein 145
chr10_+_21576909 Show fit	35.26	ENSDART00000168604 ENSDART00000166533	pcdh1a3 Links NCBI UniProt Show fit	protocadherin 1 alpha 3
chr25_-_32869794 Show fit	35.23	ENSDART00000162784	tmem266 Links NCBI UniProt Show fit	transmembrane protein 266
chr6_-_41229787 Show fit	35.18	ENSDART00000065013	synpr Links NCBI UniProt Show fit	synaptoporin
chr14_-_32258759 Show fit	35.13	ENSDART00000052949	fgf13a Links NCBI UniProt Show fit	fibroblast growth factor 13a
chr20_-_45661049 Show fit	35.06	ENSDART00000124582 ENSDART00000131251	napbb Links NCBI UniProt Show fit	N-ethylmaleimide-sensitive factor attachment protein, beta b
chr3_+_54047342 Show fit	34.92	ENSDART00000178486	olfm2a Links NCBI UniProt Show fit	olfactomedin 2a
chr8_-_14052349 Show fit	34.42	ENSDART00000135811	atp2b3a Links NCBI UniProt Show fit	ATPase plasma membrane Ca2+ transporting 3a
chr17_+_33495194 Show fit	34.40	ENSDART00000033691	pth2 Links NCBI UniProt Show fit	parathyroid hormone 2
chr20_-_29474859 Show fit	34.31	ENSDART00000152906 ENSDART00000045249	scg5 Links NCBI UniProt Show fit	secretogranin V
chr15_-_12545683 Show fit	34.29	ENSDART00000162807	scn2b Links NCBI UniProt Show fit	sodium channel, voltage-gated, type II, beta
chr7_-_35708450 Show fit	33.98	ENSDART00000193886	irx5a Links NCBI UniProt Show fit	iroquois homeobox 5a
chr7_-_31932723 Show fit	33.90	ENSDART00000014843	bdnf Links NCBI UniProt Show fit	brain-derived neurotrophic factor
chr3_-_18711288 Show fit	33.89	ENSDART00000183885	grid2ipa Links NCBI UniProt Show fit	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr7_-_52842605 Show fit	33.86	ENSDART00000083002	map1aa Links NCBI UniProt Show fit	microtubule-associated protein 1Aa
chr17_-_37214196 Show fit	33.79	ENSDART00000128715	kif3cb Links NCBI UniProt Show fit	kinesin family member 3Cb
chr8_+_47633438 Show fit	33.71	ENSDART00000139096	si:ch211-251b21.1 Links NCBI UniProt Show fit	si:ch211-251b21.1
chr14_-_18672561 Show fit	33.68	ENSDART00000166730 ENSDART00000006998	slitrk4 Links NCBI UniProt Show fit	SLIT and NTRK-like family, member 4
chr20_+_30490682 Show fit	33.67	ENSDART00000184871	myt1la Links NCBI UniProt Show fit	myelin transcription factor 1-like, a
chr6_-_35472923 Show fit	33.43	ENSDART00000185907	rgs8 Links NCBI UniProt Show fit	regulator of G protein signaling 8
chr16_-_25519762 Show fit	33.35	ENSDART00000146479 ENSDART00000142062	dtnbp1a Links NCBI UniProt Show fit	dystrobrevin binding protein 1a
chr19_+_24882845 Show fit	33.32	ENSDART00000010580	si:ch211-195b13.1 Links NCBI UniProt Show fit	si:ch211-195b13.1
chr7_+_30787903 Show fit	33.30	ENSDART00000174000	apba2b Links NCBI UniProt Show fit	amyloid beta (A4) precursor protein-binding, family A, member 2b
chr23_+_28693278 Show fit	33.24	ENSDART00000078148	smc1a Links NCBI UniProt Show fit	structural maintenance of chromosomes 1A
chr16_+_46111849 Show fit	32.87	ENSDART00000172232	sv2a Links NCBI UniProt Show fit	synaptic vesicle glycoprotein 2A
chr14_-_49063157 Show fit	32.87	ENSDART00000021260	sept8b Links NCBI UniProt Show fit	septin 8b
chr6_+_24817852 Show fit	32.79	ENSDART00000165609	barhl2 Links NCBI UniProt Show fit	BarH-like homeobox 2
chr6_+_29860776 Show fit	32.57	ENSDART00000028406	dlg1 Links NCBI UniProt Show fit	discs, large homolog 1 (Drosophila)
chr15_-_27710513 Show fit	32.33	ENSDART00000005641 ENSDART00000134373	lhx1a Links NCBI UniProt Show fit	LIM homeobox 1a
chr12_+_18681477 Show fit	32.25	ENSDART00000127981 ENSDART00000143979	rgs9b Links NCBI UniProt Show fit	regulator of G protein signaling 9b
chr11_+_39672874 Show fit	32.14	ENSDART00000046663 ENSDART00000157659	camta1b Links NCBI UniProt Show fit	calmodulin binding transcription activator 1b
chr17_-_36936649 Show fit	32.11	ENSDART00000145236	dpysl5a Links NCBI UniProt Show fit	dihydropyrimidinase-like 5a
chr17_+_5915875 Show fit	32.11	ENSDART00000184179	fndc4b Links NCBI UniProt Show fit	fibronectin type III domain containing 4b
chr7_-_28148310 Show fit	32.10	ENSDART00000044208	lmo1 Links NCBI UniProt Show fit	LIM domain only 1
chr24_-_8730913 Show fit	31.97	ENSDART00000187228 ENSDART00000082349 ENSDART00000186660	tfap2a Links NCBI UniProt Show fit	transcription factor AP-2 alpha
chr1_+_45085194 Show fit	31.91	ENSDART00000193863	si:ch211-151p13.8 Links NCBI UniProt Show fit	si:ch211-151p13.8
chr13_+_11440389 Show fit	31.91	ENSDART00000186463	zbtb18 Links NCBI UniProt Show fit	zinc finger and BTB domain containing 18
chr14_+_44545092 Show fit	31.82	ENSDART00000175454	lingo2a Links NCBI UniProt Show fit	leucine rich repeat and Ig domain containing 2a
chr10_+_15777258 Show fit	31.79	ENSDART00000140511	apba1b Links NCBI UniProt Show fit	amyloid beta (A4) precursor protein-binding, family A, member 1b
chr10_+_21650828 Show fit	31.75	ENSDART00000160754	pcdh1g1 Links NCBI UniProt Show fit	protocadherin 1 gamma 1
chr8_+_16025554 Show fit	31.63	ENSDART00000110171	elavl4 Links NCBI UniProt Show fit	ELAV like neuron-specific RNA binding protein 4
chr21_-_42007482 Show fit	31.55	ENSDART00000075740	gabrg2 Links NCBI UniProt Show fit	gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_-_26782573 Show fit	31.54	ENSDART00000090611	sh3gl2a Links NCBI UniProt Show fit	SH3 domain containing GRB2 like 2a, endophilin A1
chr18_-_8313686 Show fit	31.52	ENSDART00000182187	mapk8ip2 Links NCBI UniProt Show fit	mitogen-activated protein kinase 8 interacting protein 2
chr1_+_16397063 Show fit	31.49	ENSDART00000159794	micu3a Links NCBI UniProt Show fit	mitochondrial calcium uptake family, member 3a
chr21_-_27010796 Show fit	31.43	ENSDART00000065398 ENSDART00000144342 ENSDART00000126542	ppp1r14ba Links NCBI UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr2_+_34967210 Show fit	31.34	ENSDART00000141796	astn1 Links NCBI UniProt Show fit	astrotactin 1
chr17_-_37156520 Show fit	31.34	ENSDART00000145669	dtnbb Links NCBI UniProt Show fit	dystrobrevin, beta b
chr24_-_7699356 Show fit	31.16	ENSDART00000013117	syt5b Links NCBI UniProt Show fit	synaptotagmin Vb
chr7_+_61050329 Show fit	31.16	ENSDART00000115355	nwd2 Links NCBI UniProt Show fit	NACHT and WD repeat domain containing 2
chr1_-_56223913 Show fit	31.14	ENSDART00000019573	zgc:65894 Links NCBI UniProt Show fit	zgc:65894
chr22_+_5103349 Show fit	31.00	ENSDART00000083474	atcaya Links NCBI UniProt Show fit	ataxia, cerebellar, Cayman type a
chr4_-_5302866 Show fit	30.98	ENSDART00000138590	SNAP91 (1 of many) Links NCBI UniProt Show fit	si:ch211-214j24.9
chr10_+_29698467 Show fit	30.92	ENSDART00000163402	dlg2 Links NCBI UniProt Show fit	discs, large homolog 2 (Drosophila)
chr3_+_29714775 Show fit	30.90	ENSDART00000041388	cacng2a Links NCBI UniProt Show fit	calcium channel, voltage-dependent, gamma subunit 2a
chr8_+_22582146 Show fit	30.66	ENSDART00000157655 ENSDART00000189892	CT583651.2 Links NCBI UniProt Show fit
chr20_-_20821783 Show fit	30.66	ENSDART00000152577 ENSDART00000027603 ENSDART00000145601	ckbb Links NCBI UniProt Show fit	creatine kinase, brain b
chr25_+_7670683 Show fit	30.64	ENSDART00000040275	kcnj11l Links NCBI UniProt Show fit	potassium inwardly-rectifying channel, subfamily J, member 11, like
chr12_+_5081759 Show fit	30.51	ENSDART00000164178	prrt2 Links NCBI UniProt Show fit	proline-rich transmembrane protein 2
chr10_+_21563986 Show fit	30.37	ENSDART00000100600	pcdh1a6 Links NCBI UniProt Show fit	protocadherin 1 alpha 6
chr19_-_31522625 Show fit	30.37	ENSDART00000158438 ENSDART00000035049	necab1 Links NCBI UniProt Show fit	N-terminal EF-hand calcium binding protein 1
chr3_-_28075756 Show fit	30.13	ENSDART00000122037	rbfox1 Links NCBI UniProt Show fit	RNA binding fox-1 homolog 1
chr15_+_36115955 Show fit	30.01	ENSDART00000032702	sst1.2 Links NCBI UniProt Show fit	somatostatin 1, tandem duplicate 2
chr9_+_44430974 Show fit	29.97	ENSDART00000056846	ppp1r1c Links NCBI UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_-_46398584 Show fit	29.82	ENSDART00000193098	camk1a Links NCBI UniProt Show fit	calcium/calmodulin-dependent protein kinase Ia
chr21_-_43949208 Show fit	29.67	ENSDART00000150983	camk2a Links NCBI UniProt Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr14_-_43000836 Show fit	29.63	ENSDART00000162714	pcdh10b Links NCBI UniProt Show fit	protocadherin 10b
chr1_-_22412042 Show fit	29.60	ENSDART00000074678	chrnb3a Links NCBI UniProt Show fit	cholinergic receptor, nicotinic, beta polypeptide 3a
chr13_+_38430466 Show fit	29.52	ENSDART00000132691	adgrb3 Links NCBI UniProt Show fit	adhesion G protein-coupled receptor B3
chr20_-_28800999 Show fit	29.30	ENSDART00000049462	rab15 Links NCBI UniProt Show fit	RAB15, member RAS oncogene family
chr13_+_16522608 Show fit	29.11	ENSDART00000182838 ENSDART00000143200	kcnma1a Links NCBI UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr17_+_31185276 Show fit	29.08	ENSDART00000062887	disp2 Links NCBI UniProt Show fit	dispatched homolog 2 (Drosophila)
chr1_+_25783801 Show fit	28.92	ENSDART00000102455	gucy1a1 Links NCBI UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr14_-_34044369 Show fit	28.79	ENSDART00000149396 ENSDART00000123607 ENSDART00000190746	cyfip2 Links NCBI UniProt Show fit	cytoplasmic FMR1 interacting protein 2
chr3_-_32320537 Show fit	28.77	ENSDART00000113550 ENSDART00000168483	si:dkey-16p21.7 Links NCBI UniProt Show fit	si:dkey-16p21.7
chr19_+_14921000 Show fit	28.75	ENSDART00000144052	oprd1a Links NCBI UniProt Show fit	opioid receptor, delta 1a
chr6_-_38419318 Show fit	28.73	ENSDART00000138026	gabra5 Links NCBI UniProt Show fit	gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr4_-_193762 Show fit	28.69	ENSDART00000169667	ptpro Links NCBI UniProt Show fit	protein tyrosine phosphatase, receptor type, O
chr1_+_34203817 Show fit	28.60	ENSDART00000191432 ENSDART00000046094	arl6 Links NCBI UniProt Show fit	ADP-ribosylation factor-like 6
chr6_-_24358732 Show fit	28.46	ENSDART00000159595	ephx4 Links NCBI UniProt Show fit	epoxide hydrolase 4
chr1_-_23557877 Show fit	28.45	ENSDART00000145942	fam184b Links NCBI UniProt Show fit	family with sequence similarity 184, member B
chr17_-_45552602 Show fit	28.45	ENSDART00000154844 ENSDART00000034432	susd4 Links NCBI UniProt Show fit	sushi domain containing 4
chr21_-_39639954 Show fit	28.44	ENSDART00000026766	aldocb Links NCBI UniProt Show fit	aldolase C, fructose-bisphosphate, b
chr4_+_17279966 Show fit	28.37	ENSDART00000067005 ENSDART00000137487	bcat1 Links NCBI UniProt Show fit	branched chain amino-acid transaminase 1, cytosolic
chr23_-_29667716 Show fit	28.35	ENSDART00000158302 ENSDART00000133902	clstn1 Links NCBI UniProt Show fit	calsyntenin 1
chr3_-_28120092 Show fit	28.34	ENSDART00000151143	rbfox1 Links NCBI UniProt Show fit	RNA binding fox-1 homolog 1
chr17_-_22010668 Show fit	28.31	ENSDART00000031998	slc22a7b.1 Links NCBI UniProt Show fit	solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr10_-_24371312 Show fit	28.31	ENSDART00000149362	pitpnab Links NCBI UniProt Show fit	phosphatidylinositol transfer protein, alpha b
chr1_-_38815361 Show fit	28.23	ENSDART00000148790 ENSDART00000148572 ENSDART00000149080	asb5b Links NCBI UniProt Show fit	ankyrin repeat and SOCS box containing 5b
chr1_+_40023640 Show fit	28.22	ENSDART00000101623	lgi2b Links NCBI UniProt Show fit	leucine-rich repeat LGI family, member 2b
chr2_+_24199276 Show fit	28.19	ENSDART00000140575	map4l Links NCBI UniProt Show fit	microtubule associated protein 4 like
chr14_-_34276574 Show fit	28.02	ENSDART00000021437	gria1a Links NCBI UniProt Show fit	glutamate receptor, ionotropic, AMPA 1a
chr5_-_32323136 Show fit	27.86	ENSDART00000110804	hspb15 Links NCBI UniProt Show fit	heat shock protein, alpha-crystallin-related, b15
chr1_+_11977426 Show fit	27.85	ENSDART00000103399	tspan5b Links NCBI UniProt Show fit	tetraspanin 5b
chr5_-_3627110 Show fit	27.71	ENSDART00000156071	si:zfos-375h5.1 Links NCBI UniProt Show fit	si:zfos-375h5.1
chr20_-_10120442 Show fit	27.67	ENSDART00000144970	meis2b Links NCBI UniProt Show fit	Meis homeobox 2b
chr23_-_14918276 Show fit	27.64	ENSDART00000179831	ndrg3b Links NCBI UniProt Show fit	ndrg family member 3b
chr9_-_1702648 Show fit	27.63	ENSDART00000102934	hnrnpa3 Links NCBI UniProt Show fit	heterogeneous nuclear ribonucleoprotein A3
chr13_+_7292061 Show fit	27.54	ENSDART00000179504	CABZ01072077.1 Links NCBI UniProt Show fit	Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr19_-_32641725 Show fit	27.40	ENSDART00000165006 ENSDART00000188185	hpca Links NCBI UniProt Show fit	hippocalcin
chr3_+_46628885 Show fit	27.33	ENSDART00000006602	pde4a Links NCBI UniProt Show fit	phosphodiesterase 4A, cAMP-specific
chr24_+_14713776 Show fit	27.33	ENSDART00000134475	gdap1 Links NCBI UniProt Show fit	ganglioside induced differentiation associated protein 1
chr1_+_7679328 Show fit	27.14	ENSDART00000163488 ENSDART00000190070	en1b Links NCBI UniProt Show fit	engrailed homeobox 1b
chr2_+_24199073 Show fit	27.12	ENSDART00000144110	map4l Links NCBI UniProt Show fit	microtubule associated protein 4 like
chr23_-_29505463 Show fit	27.10	ENSDART00000050915	kif1b Links NCBI UniProt Show fit	kinesin family member 1B
chr21_-_30545121 Show fit	27.10	ENSDART00000019199	rab39ba Links NCBI UniProt Show fit	RAB39B, member RAS oncogene family a
chr13_-_33000649 Show fit	27.08	ENSDART00000133677	rbm25a Links NCBI UniProt Show fit	RNA binding motif protein 25a
chr16_-_20435475 Show fit	27.00	ENSDART00000139776	chn2 Links NCBI UniProt Show fit	chimerin 2
chr20_+_16743056 Show fit	26.99	ENSDART00000050308	calm1b Links NCBI UniProt Show fit	calmodulin 1b
chr19_-_17658160 Show fit	26.88	ENSDART00000151766 ENSDART00000170790 ENSDART00000186678 ENSDART00000188045 ENSDART00000176980 ENSDART00000166313 ENSDART00000188589	thrb Links NCBI UniProt Show fit	thyroid hormone receptor beta
chr14_-_33872092 Show fit	26.77	ENSDART00000111903	si:ch73-335m24.2 Links NCBI UniProt Show fit	si:ch73-335m24.2
chr10_+_21588002 Show fit	26.63	ENSDART00000100596	pcdh1a6 Links NCBI UniProt Show fit	protocadherin 1 alpha 6
chr10_+_21559605 Show fit	26.58	ENSDART00000123648 ENSDART00000108584	pcdh1a3 Links NCBI UniProt Show fit pcdh1a3 Links NCBI UniProt Show fit	protocadherin 1 alpha 3 protocadherin 1 alpha 3
chr20_-_26042070 Show fit	26.53	ENSDART00000140255	si:dkey-12h9.6 Links NCBI UniProt Show fit	si:dkey-12h9.6
chr16_+_32059785 Show fit	26.50	ENSDART00000134459	si:dkey-40m6.8 Links NCBI UniProt Show fit	si:dkey-40m6.8
chr12_+_24344611 Show fit	26.18	ENSDART00000093094	nrxn1a Links NCBI UniProt Show fit	neurexin 1a
chr14_-_2264494 Show fit	25.90	ENSDART00000191149	pcdh2ab9 Links NCBI UniProt Show fit	protocadherin 2 alpha b 9

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
29.3	88.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
24.4	121.8	GO:0070208	protein heterotrimerization(GO:0070208)
17.0	68.0	GO:0021742	abducens nucleus development(GO:0021742)
16.3	146.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
16.2	32.3	GO:0061213	regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
14.7	44.0	GO:0051580	regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
14.6	43.9	GO:0048917	posterior lateral line ganglion development(GO:0048917)
14.4	143.7	GO:1904071	presynaptic active zone assembly(GO:1904071)
13.7	41.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
13.6	40.7	GO:0035902	response to immobilization stress(GO:0035902)
13.5	53.8	GO:0060155	secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
13.0	38.9	GO:0002792	negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
12.3	37.0	GO:0021611	facial nerve formation(GO:0021611)
12.0	48.0	GO:0010874	regulation of cholesterol efflux(GO:0010874)
11.9	35.6	GO:0008292	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
11.4	45.5	GO:0009098	leucine biosynthetic process(GO:0009098)
11.1	55.3	GO:0016322	neuron remodeling(GO:0016322)
10.9	43.6	GO:0060074	synapse maturation(GO:0060074)
10.2	10.2	GO:0032652	interleukin-1 production(GO:0032612) regulation of interleukin-1 production(GO:0032652)
10.0	40.0	GO:0099543	trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
9.5	28.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
8.8	35.1	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
8.4	33.4	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
8.3	50.0	GO:0021767	mammillary body development(GO:0021767)
8.3	24.8	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
8.2	8.2	GO:0060031	mediolateral intercalation(GO:0060031)
8.2	32.6	GO:0038003	opioid receptor signaling pathway(GO:0038003)
8.1	24.2	GO:0021530	spinal cord oligodendrocyte cell fate specification(GO:0021530)
7.6	22.8	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
7.5	15.0	GO:0001692	histamine metabolic process(GO:0001692)
7.5	52.3	GO:0033278	cell proliferation in midbrain(GO:0033278)
7.3	132.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
7.1	21.3	GO:1901232	regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
6.9	34.3	GO:0061072	iris morphogenesis(GO:0061072)
6.7	20.2	GO:0042416	dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
6.3	143.9	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
6.0	24.2	GO:0003322	pancreatic A cell development(GO:0003322)
6.0	18.1	GO:0046069	cGMP catabolic process(GO:0046069)
5.9	11.8	GO:0002093	auditory receptor cell morphogenesis(GO:0002093)
5.8	52.4	GO:0060118	vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
5.7	23.0	GO:0046166	methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
5.7	11.5	GO:0051196	regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
5.7	102.1	GO:0072160	pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
5.7	17.0	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
5.5	149.1	GO:0016082	synaptic vesicle priming(GO:0016082)
5.4	32.4	GO:0061303	cornea development in camera-type eye(GO:0061303)
5.3	63.9	GO:0035094	response to nicotine(GO:0035094)
5.1	15.4	GO:0021960	anterior commissure morphogenesis(GO:0021960)
5.1	15.2	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
4.9	34.2	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
4.8	67.8	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
4.8	38.5	GO:0021794	thalamus development(GO:0021794)
4.8	24.0	GO:0023041	neuronal signal transduction(GO:0023041)
4.8	14.4	GO:0030858	positive regulation of epithelial cell differentiation(GO:0030858)
4.8	71.8	GO:0035493	SNARE complex assembly(GO:0035493)
4.5	13.5	GO:0061187	regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
4.5	13.4	GO:0031642	negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
4.5	71.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
4.4	40.0	GO:0061075	positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
4.4	35.5	GO:0006543	glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
4.4	39.9	GO:0045920	negative regulation of exocytosis(GO:0045920)
4.4	79.3	GO:0051932	synaptic transmission, GABAergic(GO:0051932)
4.4	13.2	GO:0060986	regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986)
4.4	79.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
4.4	43.7	GO:0071300	cellular response to retinoic acid(GO:0071300)
4.3	30.4	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
4.3	17.3	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
4.3	13.0	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
4.3	30.0	GO:0061635	regulation of protein complex stability(GO:0061635)
4.3	17.1	GO:0046552	retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
4.1	53.5	GO:0046314	phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
4.1	12.3	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
4.0	16.0	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
4.0	23.9	GO:0003232	bulbus arteriosus development(GO:0003232)
4.0	31.9	GO:0032889	regulation of vacuole fusion, non-autophagic(GO:0032889)
4.0	43.8	GO:0006798	polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
4.0	71.4	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208)
3.9	74.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
3.8	15.3	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
3.8	26.8	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
3.8	26.7	GO:0032732	positive regulation of interleukin-1 production(GO:0032732)
3.7	29.7	GO:0021553	olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
3.7	44.4	GO:0031338	regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
3.7	25.9	GO:0010996	response to auditory stimulus(GO:0010996)
3.7	59.1	GO:0048923	posterior lateral line neuromast hair cell differentiation(GO:0048923)
3.6	17.8	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
3.5	170.2	GO:0007019	microtubule depolymerization(GO:0007019)
3.5	28.2	GO:0043092	amino acid import(GO:0043090) L-amino acid import(GO:0043092)
3.4	82.7	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
3.4	16.8	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
3.3	23.4	GO:0070571	negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
3.3	36.7	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
3.3	13.3	GO:0010226	response to lithium ion(GO:0010226)
3.3	26.6	GO:0046958	learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
3.3	26.4	GO:0090594	inflammatory response to wounding(GO:0090594)
3.3	13.0	GO:0061549	sympathetic ganglion development(GO:0061549)
3.2	13.0	GO:0072116	kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
3.2	38.9	GO:0045773	positive regulation of axon extension(GO:0045773)
3.2	16.2	GO:0033119	negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
3.2	109.9	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
3.2	19.4	GO:0014015	positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
3.2	28.5	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
3.2	9.5	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
3.1	12.5	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
3.1	12.5	GO:0015677	copper ion import(GO:0015677)
3.1	25.0	GO:0072498	embryonic skeletal joint development(GO:0072498)
3.1	49.9	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
3.1	43.0	GO:0046883	regulation of hormone secretion(GO:0046883)
3.1	9.2	GO:0019695	choline metabolic process(GO:0019695)
3.0	15.1	GO:0060055	endothelial cell chemotaxis(GO:0035767) angiogenesis involved in wound healing(GO:0060055)
3.0	9.0	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
3.0	75.0	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
3.0	15.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
3.0	11.8	GO:0019532	oxalate transport(GO:0019532)
3.0	20.7	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
2.9	20.6	GO:0070073	clustering of voltage-gated calcium channels(GO:0070073)
2.9	20.6	GO:2001270	negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.9	8.7	GO:0046113	nucleobase catabolic process(GO:0046113)
2.9	99.9	GO:0050708	regulation of protein secretion(GO:0050708)
2.8	5.6	GO:0048588	developmental cell growth(GO:0048588)
2.8	56.2	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
2.8	8.4	GO:0034770	histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
2.8	25.1	GO:0035372	protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
2.8	22.1	GO:1902262	apoptotic process involved in patterning of blood vessels(GO:1902262)
2.7	13.6	GO:0014896	muscle hypertrophy(GO:0014896)
2.7	16.3	GO:2000582	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.7	8.1	GO:0010312	detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
2.7	29.8	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.7	5.4	GO:0033337	dorsal fin development(GO:0033337)
2.7	13.5	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
2.7	8.0	GO:0010893	positive regulation of steroid biosynthetic process(GO:0010893)
2.6	7.9	GO:0003403	optic vesicle formation(GO:0003403)
2.6	15.8	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
2.6	39.4	GO:0042670	retinal cone cell differentiation(GO:0042670)
2.6	7.8	GO:1990120	messenger ribonucleoprotein complex assembly(GO:1990120)
2.6	10.3	GO:0051012	microtubule sliding(GO:0051012)
2.6	25.7	GO:0044805	late nucleophagy(GO:0044805)
2.6	7.7	GO:0060292	long term synaptic depression(GO:0060292)
2.6	23.0	GO:0001964	startle response(GO:0001964)
2.6	20.4	GO:0006895	Golgi to endosome transport(GO:0006895)
2.5	53.5	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.5	20.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
2.5	12.6	GO:0007624	ultradian rhythm(GO:0007624)
2.5	9.9	GO:0071387	cellular response to cortisol stimulus(GO:0071387)
2.5	19.6	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
2.5	27.0	GO:0016199	axon midline choice point recognition(GO:0016199)
2.4	24.0	GO:0045666	positive regulation of neuron differentiation(GO:0045666)
2.4	43.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
2.4	7.2	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
2.4	19.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
2.4	47.2	GO:0097061	dendritic spine organization(GO:0097061)
2.3	155.0	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
2.3	57.6	GO:0099645	protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
2.3	11.5	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
2.3	211.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
2.3	22.9	GO:0061588	calcium activated phospholipid scrambling(GO:0061588)
2.3	27.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
2.3	15.8	GO:1990504	dense core granule exocytosis(GO:1990504)
2.2	15.7	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.2	17.9	GO:2000272	negative regulation of receptor activity(GO:2000272)
2.2	24.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
2.2	13.3	GO:0048795	swim bladder morphogenesis(GO:0048795)
2.2	28.8	GO:0097120	receptor localization to synapse(GO:0097120)
2.2	17.6	GO:0035264	multicellular organism growth(GO:0035264)
2.2	41.7	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
2.2	10.8	GO:0034553	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.1	32.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
2.1	23.1	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
2.1	10.5	GO:0071881	adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
2.1	21.0	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
2.1	6.3	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.0	6.1	GO:1902571	regulation of serine-type peptidase activity(GO:1902571)
2.0	18.0	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011)
2.0	69.4	GO:0043652	engulfment of apoptotic cell(GO:0043652)
2.0	9.9	GO:0022029	forebrain cell migration(GO:0021885) telencephalon cell migration(GO:0022029)
2.0	5.9	GO:1902534	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
2.0	33.5	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
2.0	7.8	GO:0048339	paraxial mesoderm development(GO:0048339)
2.0	15.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
2.0	462.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.9	7.8	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.9	17.3	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
1.9	11.4	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
1.9	33.9	GO:1902287	semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.9	11.3	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
1.9	22.3	GO:0042407	cristae formation(GO:0042407)
1.8	7.4	GO:0035124	embryonic caudal fin morphogenesis(GO:0035124)
1.8	5.5	GO:0035973	aggrephagy(GO:0035973)
1.8	7.4	GO:1902042	regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.8	12.8	GO:0021871	forebrain regionalization(GO:0021871)
1.8	51.1	GO:0070831	basement membrane assembly(GO:0070831)
1.8	5.5	GO:0032780	negative regulation of ATPase activity(GO:0032780)
1.8	17.7	GO:0048935	peripheral nervous system neuron development(GO:0048935)
1.8	12.3	GO:0042311	vasodilation(GO:0042311)
1.7	10.5	GO:1990108	protein linear deubiquitination(GO:1990108)
1.7	8.7	GO:0055016	hypochord development(GO:0055016)
1.7	13.8	GO:0046323	glucose import(GO:0046323)
1.7	17.1	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.7	12.0	GO:0036268	swimming(GO:0036268)
1.7	17.0	GO:0046548	retinal rod cell development(GO:0046548)
1.7	8.5	GO:1901909	diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.7	23.3	GO:0007622	rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
1.7	26.5	GO:0008053	mitochondrial fusion(GO:0008053)
1.7	33.0	GO:0040023	nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
1.6	26.4	GO:0036065	fucosylation(GO:0036065)
1.6	21.4	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
1.6	4.9	GO:1903332	regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
1.6	11.3	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.6	19.3	GO:0017121	phospholipid scrambling(GO:0017121)
1.6	38.0	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
1.6	31.4	GO:0006198	cAMP catabolic process(GO:0006198)
1.6	31.2	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.5	12.3	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.5	10.6	GO:0050848	regulation of calcium-mediated signaling(GO:0050848)
1.5	22.7	GO:0045116	protein neddylation(GO:0045116)
1.5	10.4	GO:0099560	synaptic membrane adhesion(GO:0099560)
1.5	5.9	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
1.5	39.4	GO:0048263	determination of dorsal identity(GO:0048263)
1.5	55.3	GO:0032400	melanosome localization(GO:0032400)
1.5	8.7	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
1.4	11.4	GO:0071557	histone H3-K27 demethylation(GO:0071557)
1.4	22.7	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
1.4	19.7	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.4	2.8	GO:0048211	Golgi vesicle docking(GO:0048211)
1.4	22.4	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
1.4	6.9	GO:0030431	sleep(GO:0030431)
1.4	9.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.4	2.7	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
1.4	5.5	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
1.4	40.6	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.3	5.3	GO:0050955	thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
1.3	18.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
1.3	8.0	GO:0071569	protein ufmylation(GO:0071569)
1.3	26.3	GO:0033344	cholesterol efflux(GO:0033344)
1.3	9.2	GO:0007288	sperm axoneme assembly(GO:0007288)
1.3	17.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
1.3	7.7	GO:0000455	enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
1.3	16.6	GO:0045851	vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
1.3	6.4	GO:0003422	growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
1.3	3.8	GO:0008344	adult locomotory behavior(GO:0008344)
1.3	3.8	GO:0003404	optic vesicle morphogenesis(GO:0003404)
1.3	7.6	GO:0015846	polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
1.3	7.6	GO:0097198	histone H3-K36 trimethylation(GO:0097198)
1.3	3.8	GO:0000338	protein deneddylation(GO:0000338)
1.2	8.7	GO:0007634	optokinetic behavior(GO:0007634)
1.2	11.2	GO:0015886	heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
1.2	4.9	GO:0032790	ribosome disassembly(GO:0032790)
1.2	20.6	GO:0015693	magnesium ion transport(GO:0015693)
1.2	23.1	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
1.2	21.7	GO:0019228	neuronal action potential(GO:0019228)
1.2	6.0	GO:0046485	ether lipid metabolic process(GO:0046485)
1.2	13.2	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
1.2	4.8	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
1.2	3.5	GO:0018872	arsonoacetate metabolic process(GO:0018872)
1.2	18.9	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
1.2	3.5	GO:0001779	natural killer cell differentiation(GO:0001779)
1.2	31.2	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
1.1	8.0	GO:1902093	positive regulation of sperm motility(GO:1902093)
1.1	9.1	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.1	7.9	GO:0018344	protein geranylgeranylation(GO:0018344)
1.1	15.7	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
1.1	5.6	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
1.1	13.4	GO:0039020	pronephric nephron tubule development(GO:0039020)
1.1	28.7	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
1.1	40.4	GO:0036269	swimming behavior(GO:0036269)
1.1	27.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
1.1	23.8	GO:0030032	lamellipodium assembly(GO:0030032)
1.1	15.1	GO:0036158	outer dynein arm assembly(GO:0036158)
1.1	2.2	GO:0048798	swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
1.1	21.3	GO:0015872	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) dopamine transport(GO:0015872)
1.1	3.2	GO:0038084	vascular endothelial growth factor signaling pathway(GO:0038084)
1.0	42.8	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
1.0	245.4	GO:0043547	positive regulation of GTPase activity(GO:0043547)
1.0	4.1	GO:0061709	reticulophagy(GO:0061709)
1.0	288.5	GO:0099536	synaptic signaling(GO:0099536)
1.0	8.0	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.0	15.0	GO:0070286	axonemal dynein complex assembly(GO:0070286)
1.0	8.9	GO:1902547	regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
1.0	20.7	GO:0007020	microtubule nucleation(GO:0007020)
1.0	7.9	GO:0002279	mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation involved in immune response(GO:0033006) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
1.0	8.8	GO:0002690	mast cell chemotaxis(GO:0002551) positive regulation of leukocyte chemotaxis(GO:0002690) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
1.0	2.9	GO:0050666	regulation of sulfur amino acid metabolic process(GO:0031335) regulation of sulfur metabolic process(GO:0042762) regulation of homocysteine metabolic process(GO:0050666)
1.0	34.9	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.0	5.8	GO:2001224	positive regulation of neuron migration(GO:2001224)
1.0	27.8	GO:0021587	cerebellum morphogenesis(GO:0021587)
1.0	3.8	GO:0048321	axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
1.0	8.6	GO:0006465	signal peptide processing(GO:0006465)
0.9	4.7	GO:0032418	lysosome localization(GO:0032418)
0.9	14.2	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.9	8.5	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.9	3.7	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.9	6.5	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.9	4.6	GO:0010586	miRNA metabolic process(GO:0010586)
0.9	20.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.9	2.8	GO:0048569	post-embryonic organ development(GO:0048569)
0.9	8.2	GO:0098789	mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.9	33.8	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.9	2.7	GO:0061462	protein localization to lysosome(GO:0061462)
0.9	4.5	GO:0030242	pexophagy(GO:0030242)
0.9	4.5	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.9	9.9	GO:0021592	fourth ventricle development(GO:0021592)
0.9	2.7	GO:0071918	urea transmembrane transport(GO:0071918)
0.9	2.7	GO:0051095	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.9	6.2	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.9	19.6	GO:0000187	activation of MAPK activity(GO:0000187)
0.9	6.2	GO:0097009	energy homeostasis(GO:0097009)
0.9	13.1	GO:0051127	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.9	12.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.9	7.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.9	31.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.9	457.5	GO:0031175	neuron projection development(GO:0031175)
0.8	11.9	GO:0014003	oligodendrocyte development(GO:0014003)
0.8	62.0	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.8	6.7	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.8	8.4	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.8	7.5	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.8	24.8	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.8	3.3	GO:0014909	smooth muscle cell migration(GO:0014909)
0.8	10.5	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.8	42.1	GO:0015914	phospholipid transport(GO:0015914)
0.8	23.4	GO:0060319	primitive erythrocyte differentiation(GO:0060319)
0.8	2.4	GO:0060765	androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.8	9.6	GO:0006020	inositol metabolic process(GO:0006020)
0.8	16.8	GO:1901214	regulation of neuron death(GO:1901214)
0.8	3.9	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.8	3.1	GO:2000178	negative regulation of neural precursor cell proliferation(GO:2000178)
0.8	15.5	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8	7.7	GO:0006868	glutamine transport(GO:0006868)
0.8	6.2	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.8	9.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.8	5.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.8	3.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.8	1.5	GO:0071042	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.7	37.4	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.7	3.7	GO:0046850	regulation of bone remodeling(GO:0046850)
0.7	31.5	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.7	13.1	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.7	8.7	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.7	3.6	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.7	7.3	GO:0015800	acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.7	3.6	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.7	58.0	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.7	3.6	GO:0000012	single strand break repair(GO:0000012)
0.7	31.2	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.7	11.8	GO:0021761	limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.7	15.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.7	114.6	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)
0.7	6.1	GO:0070475	rRNA base methylation(GO:0070475)
0.6	8.4	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6	11.0	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.6	2.6	GO:0001839	neural plate morphogenesis(GO:0001839)
0.6	1.9	GO:0009193	ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.6	4.4	GO:0016540	protein autoprocessing(GO:0016540)
0.6	6.9	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.6	53.3	GO:0072659	protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.6	12.5	GO:0032456	endocytic recycling(GO:0032456)
0.6	16.1	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.6	4.3	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.6	9.3	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.6	14.9	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.6	2.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.6	7.3	GO:0000154	rRNA modification(GO:0000154)
0.6	8.4	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.6	12.0	GO:0055064	chloride ion homeostasis(GO:0055064)
0.6	2.4	GO:0035521	monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6	12.0	GO:0048634	regulation of muscle organ development(GO:0048634)
0.6	16.2	GO:0032482	Rab protein signal transduction(GO:0032482)
0.6	7.2	GO:0031057	negative regulation of histone modification(GO:0031057)
0.6	2.4	GO:0046168	NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.6	2.4	GO:0038161	prolactin signaling pathway(GO:0038161)
0.6	29.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.6	7.7	GO:0048854	brain morphogenesis(GO:0048854)
0.6	2.4	GO:0051645	Golgi localization(GO:0051645)
0.6	4.7	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.6	7.1	GO:0009648	photoperiodism(GO:0009648)
0.6	6.4	GO:0046683	response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.6	4.6	GO:0070654	sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.6	59.9	GO:0051260	protein homooligomerization(GO:0051260)
0.6	10.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.6	11.5	GO:1990035	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.6	10.8	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.6	9.5	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.6	2.8	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.5	7.1	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.5	2.7	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.5	7.5	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.5	8.6	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.5	32.6	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.5	3.2	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centriole replication(GO:0046600) negative regulation of centrosome cycle(GO:0046606)
0.5	1.6	GO:0050748	N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.5	11.1	GO:0035082	axoneme assembly(GO:0035082)
0.5	19.7	GO:0046328	regulation of JNK cascade(GO:0046328)
0.5	2.1	GO:0003400	regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.5	21.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.5	5.6	GO:0046847	filopodium assembly(GO:0046847)
0.5	13.6	GO:0035118	embryonic pectoral fin morphogenesis(GO:0035118)
0.5	17.5	GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.5	3.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.5	3.8	GO:0044211	CTP salvage(GO:0044211)
0.5	10.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.5	26.8	GO:0003341	cilium movement(GO:0003341)
0.5	0.9	GO:1904357	negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.5	5.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.5	6.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.5	1.4	GO:0070417	cellular response to cold(GO:0070417)
0.5	2.3	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.5	2.7	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5	6.3	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.4	1.8	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.4	1.3	GO:0010664	negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.4	30.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.4	1.3	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4	4.7	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.4	2.9	GO:0016266	O-glycan processing(GO:0016266)
0.4	3.4	GO:0006566	threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4	1.7	GO:0070555	response to interleukin-1(GO:0070555) cellular response to interleukin-1(GO:0071347)
0.4	18.8	GO:0043484	regulation of RNA splicing(GO:0043484)
0.4	0.4	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.4	2.8	GO:0045444	fat cell differentiation(GO:0045444)
0.4	9.7	GO:0030322	stabilization of membrane potential(GO:0030322)
0.4	5.8	GO:0002574	thrombocyte differentiation(GO:0002574)
0.4	1.5	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.4	3.0	GO:0021772	olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.4	32.2	GO:0006475	internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394)
0.4	4.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.4	6.8	GO:1901663	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.4	2.8	GO:0006478	protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.3	29.6	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.3	6.9	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.3	4.4	GO:1902017	regulation of cilium assembly(GO:1902017)
0.3	17.9	GO:0099518	vesicle cytoskeletal trafficking(GO:0099518)
0.3	43.2	GO:0007018	microtubule-based movement(GO:0007018)
0.3	3.0	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3	19.4	GO:0019722	calcium-mediated signaling(GO:0019722)
0.3	5.8	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.3	11.5	GO:0031647	regulation of protein stability(GO:0031647)
0.3	4.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	4.6	GO:0006265	DNA topological change(GO:0006265)
0.3	17.4	GO:0006476	protein deacetylation(GO:0006476)
0.3	8.2	GO:0060968	regulation of gene silencing(GO:0060968)
0.3	2.1	GO:2000404	regulation of T cell migration(GO:2000404)
0.3	2.1	GO:0097477	spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3	12.3	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3	2.0	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.3	1.7	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.3	1.7	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3	27.6	GO:0070588	calcium ion transmembrane transport(GO:0070588)
0.3	1.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.3	9.4	GO:0016126	sterol biosynthetic process(GO:0016126)
0.3	5.9	GO:0003094	glomerular filtration(GO:0003094)
0.3	10.9	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.3	9.0	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.3	50.0	GO:0006470	protein dephosphorylation(GO:0006470)
0.3	2.8	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2	1.5	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2	11.3	GO:0007338	single fertilization(GO:0007338)
0.2	12.6	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.2	5.3	GO:0043249	erythrocyte maturation(GO:0043249)
0.2	1.7	GO:0072554	endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.2	1.6	GO:0031179	peptide modification(GO:0031179)
0.2	0.6	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2	3.1	GO:0030705	cytoskeleton-dependent intracellular transport(GO:0030705)
0.2	5.3	GO:0007062	sister chromatid cohesion(GO:0007062)
0.2	2.8	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.2	5.0	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.2	6.5	GO:0034111	negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.2	3.2	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.2	1.6	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2	1.0	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.2	5.5	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.2	2.0	GO:0018345	protein palmitoylation(GO:0018345)
0.2	4.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	7.9	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.2	1.9	GO:0006513	protein monoubiquitination(GO:0006513)
0.2	3.3	GO:0035195	gene silencing by miRNA(GO:0035195)
0.2	6.2	GO:0043087	regulation of GTPase activity(GO:0043087)
0.2	1.8	GO:0097178	ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.1	2.2	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	0.3	GO:0038171	cannabinoid signaling pathway(GO:0038171)
0.1	1.4	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.1	0.6	GO:0051788	response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1	1.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	3.4	GO:0016574	histone ubiquitination(GO:0016574)
0.1	1.3	GO:0038203	TORC2 signaling(GO:0038203)
0.1	8.8	GO:0016579	protein deubiquitination(GO:0016579)
0.1	1.0	GO:0019430	response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1	0.4	GO:0035138	pectoral fin morphogenesis(GO:0035138)
0.1	1.4	GO:0032438	melanosome organization(GO:0032438)
0.1	0.7	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	0.7	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1	0.4	GO:0015740	C4-dicarboxylate transport(GO:0015740)
0.1	0.5	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	1.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.4	GO:0039689	viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.1	1.4	GO:0016926	protein desumoylation(GO:0016926)
0.1	0.9	GO:1901072	glucosamine-containing compound catabolic process(GO:1901072)
0.1	0.6	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	1.8	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.1	0.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	4.8	GO:0010506	regulation of autophagy(GO:0010506)
0.1	2.4	GO:0030488	tRNA methylation(GO:0030488)
0.1	13.5	GO:0006486	protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1	20.1	GO:0046777	protein autophosphorylation(GO:0046777)
0.1	0.1	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.1	1.7	GO:0006672	ceramide metabolic process(GO:0006672)
0.1	1.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.1	0.2	GO:0042148	strand invasion(GO:0042148)
0.1	4.0	GO:0007034	vacuolar transport(GO:0007034)
0.1	0.9	GO:0031503	protein complex localization(GO:0031503)
0.0	0.7	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.5	GO:0006536	glutamate metabolic process(GO:0006536)
0.0	0.2	GO:1900048	positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0	0.6	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.1	GO:0006517	protein deglycosylation(GO:0006517)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.3	109.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
17.4	104.6	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
14.4	143.7	GO:0098982	GABA-ergic synapse(GO:0098982)
11.0	66.2	GO:0005955	calcineurin complex(GO:0005955)
9.6	57.3	GO:0043083	synaptic cleft(GO:0043083)
9.5	28.4	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
8.8	35.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
7.5	22.6	GO:0030906	retromer, cargo-selective complex(GO:0030906)
7.4	14.7	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
7.3	7.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
7.1	21.2	GO:0008275	gamma-tubulin small complex(GO:0008275)
6.9	234.5	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
6.3	278.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
5.8	17.5	GO:0032839	dendrite cytoplasm(GO:0032839)
5.6	55.7	GO:0042583	chromaffin granule(GO:0042583)
5.5	5.5	GO:0042575	DNA polymerase complex(GO:0042575)
4.9	59.1	GO:0044295	axonal growth cone(GO:0044295)
4.7	198.5	GO:0030426	growth cone(GO:0030426)
4.6	346.7	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
4.6	142.8	GO:0043679	axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
4.4	88.6	GO:0031594	neuromuscular junction(GO:0031594)
4.3	13.0	GO:0098826	endoplasmic reticulum tubular network membrane(GO:0098826)
4.2	62.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
4.0	31.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
3.8	50.0	GO:1990246	uniplex complex(GO:1990246)
3.8	91.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
3.3	13.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
3.3	23.2	GO:0043194	axon initial segment(GO:0043194)
3.1	21.8	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
3.1	49.0	GO:0031209	SCAR complex(GO:0031209)
3.0	35.6	GO:0030893	meiotic cohesin complex(GO:0030893)
2.9	23.5	GO:0044232	organelle membrane contact site(GO:0044232)
2.9	20.2	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.9	23.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
2.8	50.5	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
2.7	2.7	GO:0071564	npBAF complex(GO:0071564)
2.6	21.2	GO:0016586	RSC complex(GO:0016586)
2.6	23.6	GO:0030122	AP-2 adaptor complex(GO:0030122)
2.6	18.2	GO:0033270	paranode region of axon(GO:0033270)
2.6	7.8	GO:0042382	paraspeckles(GO:0042382)
2.6	10.3	GO:0008247	1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
2.6	23.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
2.5	19.8	GO:0034464	BBSome(GO:0034464)
2.5	7.4	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.4	16.8	GO:0033010	paranodal junction(GO:0033010)
2.4	165.1	GO:0031201	SNARE complex(GO:0031201)
2.3	217.8	GO:0008021	synaptic vesicle(GO:0008021)
2.3	22.6	GO:0036449	microtubule minus-end(GO:0036449)
2.2	36.8	GO:0043209	myelin sheath(GO:0043209)
2.2	8.7	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
2.2	154.9	GO:0043025	neuronal cell body(GO:0043025)
2.1	27.7	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
2.1	6.4	GO:0032591	dendritic spine membrane(GO:0032591)
2.1	40.3	GO:0098831	presynaptic active zone cytoplasmic component(GO:0098831)
2.1	12.7	GO:0030877	beta-catenin destruction complex(GO:0030877)
2.1	128.5	GO:0034704	calcium channel complex(GO:0034704)
2.1	6.3	GO:0005828	kinetochore microtubule(GO:0005828)
2.1	34.9	GO:0030008	TRAPP complex(GO:0030008)
2.0	50.8	GO:0005921	gap junction(GO:0005921)
2.0	41.9	GO:0002116	semaphorin receptor complex(GO:0002116)
2.0	7.9	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
2.0	15.8	GO:0005614	interstitial matrix(GO:0005614)
1.9	44.5	GO:0048786	presynaptic active zone(GO:0048786)
1.9	20.4	GO:0061617	MICOS complex(GO:0061617)
1.8	9.0	GO:0008091	spectrin(GO:0008091)
1.8	113.5	GO:0031225	anchored component of membrane(GO:0031225)
1.8	25.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.8	17.9	GO:0045171	intercellular bridge(GO:0045171)
1.8	214.4	GO:0045211	postsynaptic membrane(GO:0045211)
1.8	31.6	GO:0005640	nuclear outer membrane(GO:0005640)
1.7	98.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
1.6	185.1	GO:0014069	postsynaptic density(GO:0014069)
1.6	31.0	GO:0044666	MLL3/4 complex(GO:0044666)
1.6	45.6	GO:0098978	glutamatergic synapse(GO:0098978)
1.6	48.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
1.6	109.0	GO:0030141	secretory granule(GO:0030141)
1.6	4.9	GO:0072380	TRC complex(GO:0072380)
1.6	35.3	GO:0043256	basal lamina(GO:0005605) laminin complex(GO:0043256)
1.5	26.3	GO:0060170	ciliary membrane(GO:0060170)
1.5	40.8	GO:0000407	pre-autophagosomal structure(GO:0000407)
1.5	29.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
1.5	7.4	GO:0070724	BMP receptor complex(GO:0070724)
1.5	33.7	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.4	17.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
1.4	10.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
1.4	5.5	GO:0046695	SLIK (SAGA-like) complex(GO:0046695)
1.4	112.9	GO:0005871	kinesin complex(GO:0005871)
1.3	13.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
1.3	3.9	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
1.3	10.4	GO:0032783	ELL-EAF complex(GO:0032783)
1.3	551.7	GO:0043005	neuron projection(GO:0043005)
1.3	6.4	GO:0005673	transcription factor TFIIE complex(GO:0005673)
1.3	8.9	GO:0001650	fibrillar center(GO:0001650)
1.2	15.0	GO:0030126	COPI vesicle coat(GO:0030126)
1.2	27.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
1.2	26.9	GO:0030125	clathrin vesicle coat(GO:0030125)
1.2	8.5	GO:0000172	ribonuclease MRP complex(GO:0000172)
1.2	21.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
1.2	4.8	GO:0097268	cytoophidium(GO:0097268)
1.2	9.5	GO:0001401	mitochondrial sorting and assembly machinery complex(GO:0001401)
1.2	13.0	GO:0000124	SAGA complex(GO:0000124)
1.2	5.8	GO:0071203	WASH complex(GO:0071203)
1.1	9.1	GO:0071914	prominosome(GO:0071914)
1.1	5.5	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
1.1	6.6	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
1.1	10.9	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.1	2.1	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
1.1	15.8	GO:0098802	plasma membrane receptor complex(GO:0098802)
1.0	10.4	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.0	12.4	GO:0036038	MKS complex(GO:0036038)
1.0	4.1	GO:0005880	nuclear microtubule(GO:0005880)
1.0	3.1	GO:0031417	NatC complex(GO:0031417)
1.0	20.0	GO:0034399	nuclear periphery(GO:0034399)
1.0	8.0	GO:0097225	sperm midpiece(GO:0097225)
1.0	119.1	GO:0045202	synapse(GO:0045202)
1.0	31.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.0	6.8	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
1.0	23.4	GO:0005844	polysome(GO:0005844)
0.9	2.7	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.9	2.7	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.8	3.4	GO:0016589	NURF complex(GO:0016589)
0.8	79.9	GO:0005802	trans-Golgi network(GO:0005802)
0.8	3.3	GO:0070319	Golgi to plasma membrane transport vesicle(GO:0070319)
0.8	18.0	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.8	3.2	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.8	3.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.8	7.0	GO:0071797	LUBAC complex(GO:0071797)
0.8	10.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.7	19.2	GO:0000145	exocyst(GO:0000145)
0.7	3.5	GO:0033503	HULC complex(GO:0033503)
0.7	4.7	GO:0031083	BLOC-1 complex(GO:0031083)
0.7	12.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.6	5.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.6	1.9	GO:1990879	CST complex(GO:1990879)
0.6	2.5	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.6	3.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.6	4.3	GO:0070847	core mediator complex(GO:0070847)
0.6	9.1	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.6	1.2	GO:0035253	ciliary rootlet(GO:0035253)
0.6	7.0	GO:0000815	ESCRT III complex(GO:0000815)
0.6	7.5	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.6	4.6	GO:0030670	endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.6	12.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.5	7.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.5	16.2	GO:0030286	dynein complex(GO:0030286)
0.5	1.6	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.5	10.8	GO:0070822	Sin3-type complex(GO:0070822)
0.5	14.5	GO:0000922	spindle pole(GO:0000922)
0.5	2.9	GO:0071986	Ragulator complex(GO:0071986)
0.5	2.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.4	6.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.4	1.3	GO:0032040	small-subunit processome(GO:0032040)
0.4	24.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.4	5.3	GO:0008278	cohesin complex(GO:0008278)
0.4	4.8	GO:0005675	holo TFIIH complex(GO:0005675)
0.4	1.7	GO:0097519	DNA recombinase complex(GO:0097519)
0.4	40.7	GO:0005770	late endosome(GO:0005770)
0.4	12.0	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.4	33.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.4	25.5	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.4	51.3	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.4	2.3	GO:0005845	mRNA cap binding complex(GO:0005845)
0.4	5.3	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.4	9.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.4	7.0	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.4	13.9	GO:0031970	mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.4	8.9	GO:0000421	autophagosome membrane(GO:0000421)
0.3	2.4	GO:0035517	PR-DUB complex(GO:0035517)
0.3	4.6	GO:0030056	hemidesmosome(GO:0030056)
0.3	2.3	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3	13.7	GO:0030659	cytoplasmic vesicle membrane(GO:0030659)
0.3	2.9	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.3	11.9	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3	4.0	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.3	14.1	GO:0031514	motile cilium(GO:0031514)
0.3	64.8	GO:0005768	endosome(GO:0005768)
0.3	319.7	GO:0031226	intrinsic component of plasma membrane(GO:0031226)
0.3	13.4	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3	6.6	GO:0071565	nBAF complex(GO:0071565)
0.3	3.9	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.3	74.4	GO:0000139	Golgi membrane(GO:0000139)
0.3	1.3	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.2	22.6	GO:0005874	microtubule(GO:0005874)
0.2	2.4	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	89.5	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.2	0.6	GO:0070578	RISC-loading complex(GO:0070578)
0.2	2.0	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2	1.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	11.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.2	4.5	GO:0035861	site of double-strand break(GO:0035861)
0.2	2.4	GO:0032993	protein-DNA complex(GO:0032993)
0.2	12.6	GO:0005925	focal adhesion(GO:0005925)
0.1	3.0	GO:0030175	filopodium(GO:0030175)
0.1	1.5	GO:0000176	nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	0.7	GO:0055087	Ski complex(GO:0055087)
0.1	1.6	GO:0030427	site of polarized growth(GO:0030427)
0.1	658.6	GO:0005634	nucleus(GO:0005634)
0.1	0.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	1.3	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.6	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.2	GO:0043514	interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0	0.6	GO:0005902	microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
33.3	99.8	GO:1903136	cuprous ion binding(GO:1903136)
29.3	88.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
27.3	109.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
18.2	273.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
16.3	97.9	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
15.8	63.4	GO:0044548	S100 protein binding(GO:0044548)
14.4	201.1	GO:0008503	benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
11.4	45.5	GO:0052656	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
11.0	66.2	GO:0033192	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
9.7	29.1	GO:0050135	NAD(P)+ nucleosidase activity(GO:0050135)
9.7	174.5	GO:0098882	structural constituent of presynaptic active zone(GO:0098882)
9.6	385.5	GO:0017075	syntaxin-1 binding(GO:0017075)
9.6	28.7	GO:0038046	enkephalin receptor activity(GO:0038046)
8.9	35.7	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
7.5	89.7	GO:0004157	dihydropyrimidinase activity(GO:0004157)
7.1	42.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
6.7	26.9	GO:0070324	thyroid hormone binding(GO:0070324)
5.8	23.2	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
5.7	23.0	GO:0004807	triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
4.9	14.7	GO:0042165	neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
4.8	24.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
4.8	14.4	GO:0031716	calcitonin receptor binding(GO:0031716)
4.6	23.1	GO:0008046	axon guidance receptor activity(GO:0008046)
4.6	41.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
4.5	58.5	GO:0031628	opioid receptor binding(GO:0031628)
4.5	13.4	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
4.4	17.8	GO:0002151	G-quadruplex RNA binding(GO:0002151)
4.4	21.8	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
4.3	103.6	GO:0001540	beta-amyloid binding(GO:0001540)
4.3	72.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
4.1	74.5	GO:0004383	guanylate cyclase activity(GO:0004383)
4.1	53.5	GO:0004111	creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
4.1	12.3	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
4.1	8.1	GO:0008200	ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
4.0	28.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
4.0	31.9	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
4.0	43.8	GO:0004309	exopolyphosphatase activity(GO:0004309)
3.9	35.5	GO:0004359	glutaminase activity(GO:0004359)
3.9	189.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
3.9	15.7	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
3.9	27.2	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
3.8	23.0	GO:0030331	estrogen receptor binding(GO:0030331)
3.8	49.1	GO:0005165	nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
3.8	64.1	GO:0045159	myosin II binding(GO:0045159)
3.7	51.9	GO:0008327	methyl-CpG binding(GO:0008327)
3.7	77.9	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
3.6	28.4	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
3.5	14.2	GO:0050333	thiamin-triphosphatase activity(GO:0050333)
3.5	31.4	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
3.4	91.9	GO:0017080	sodium channel regulator activity(GO:0017080)
3.4	16.9	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
3.3	9.9	GO:1990226	histone methyltransferase binding(GO:1990226)
3.3	16.5	GO:0070004	cysteine-type exopeptidase activity(GO:0070004)
3.3	42.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
3.1	62.8	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
3.1	15.7	GO:0070300	phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611)
3.1	12.5	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
3.1	9.4	GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
3.0	36.4	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
3.0	9.0	GO:0016436	rRNA (uridine) methyltransferase activity(GO:0016436)
3.0	12.0	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
2.9	26.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.9	8.7	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.9	86.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
2.9	23.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
2.9	11.5	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
2.9	17.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.8	54.0	GO:0008301	DNA binding, bending(GO:0008301)
2.8	14.2	GO:0033842	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
2.8	45.3	GO:0048018	receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
2.8	8.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
2.7	39.9	GO:0019211	phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
2.6	23.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.6	44.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
2.5	53.5	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.5	42.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
2.5	15.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
2.5	12.5	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
2.5	22.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
2.5	36.8	GO:0019911	structural constituent of myelin sheath(GO:0019911)
2.4	7.3	GO:0052834	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
2.4	24.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
2.4	7.2	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
2.4	9.6	GO:0001607	neuromedin U receptor activity(GO:0001607)
2.4	9.6	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
2.4	7.2	GO:0061599	molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
2.4	12.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
2.4	19.1	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
2.4	14.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.4	30.6	GO:0016413	O-acetyltransferase activity(GO:0016413)
2.2	4.5	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
2.2	19.8	GO:0048039	ubiquinone binding(GO:0048039)
2.2	83.0	GO:0030145	manganese ion binding(GO:0030145)
2.2	15.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.1	6.3	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.1	56.3	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
2.1	31.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
2.1	26.8	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
2.0	12.3	GO:0033781	cholesterol 24-hydroxylase activity(GO:0033781)
2.0	6.1	GO:0001729	ceramide kinase activity(GO:0001729)
2.0	57.0	GO:0004089	carbonate dehydratase activity(GO:0004089)
2.0	10.2	GO:0008743	L-threonine 3-dehydrogenase activity(GO:0008743)
2.0	10.2	GO:1902387	ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
2.0	97.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
2.0	6.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
2.0	8.1	GO:0033149	FFAT motif binding(GO:0033149)
2.0	28.2	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
2.0	28.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
2.0	26.0	GO:0030507	spectrin binding(GO:0030507)
2.0	7.9	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
2.0	27.5	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.9	60.1	GO:0017154	semaphorin receptor activity(GO:0017154)
1.9	32.4	GO:0008417	fucosyltransferase activity(GO:0008417)
1.9	1.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
1.9	5.6	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.8	11.1	GO:0097363	protein O-GlcNAc transferase activity(GO:0097363)
1.8	11.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.8	19.6	GO:0005326	neurotransmitter transporter activity(GO:0005326)
1.8	10.7	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
1.8	21.3	GO:0051011	microtubule minus-end binding(GO:0051011)
1.8	42.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
1.8	14.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.8	10.5	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
1.7	34.6	GO:0022829	wide pore channel activity(GO:0022829)
1.7	8.5	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.7	6.7	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.7	33.4	GO:0016917	GABA receptor activity(GO:0016917)
1.7	57.9	GO:0051010	microtubule plus-end binding(GO:0051010)
1.6	26.3	GO:0017136	histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
1.6	25.9	GO:0042910	xenobiotic transporter activity(GO:0042910)
1.6	19.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.6	4.7	GO:0004061	arylformamidase activity(GO:0004061)
1.6	14.0	GO:0030547	receptor inhibitor activity(GO:0030547)
1.5	6.2	GO:0031782	type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
1.5	23.1	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
1.5	50.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.5	33.1	GO:0050321	tau-protein kinase activity(GO:0050321)
1.5	13.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.5	47.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
1.5	13.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.5	13.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.5	24.7	GO:0005272	sodium channel activity(GO:0005272)
1.5	7.3	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.4	5.8	GO:0033745	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
1.4	32.7	GO:0016854	racemase and epimerase activity(GO:0016854)
1.4	18.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
1.4	19.7	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.4	21.8	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
1.4	48.6	GO:0019003	GDP binding(GO:0019003)
1.3	144.1	GO:0005516	calmodulin binding(GO:0005516)
1.3	8.0	GO:0008158	hedgehog receptor activity(GO:0008158)
1.3	10.6	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
1.3	25.0	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
1.3	3.9	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
1.3	6.5	GO:0004307	diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
1.3	3.9	GO:0042903	tubulin deacetylase activity(GO:0042903)
1.3	5.1	GO:0017020	myosin phosphatase regulator activity(GO:0017020)
1.3	7.6	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
1.2	1.2	GO:0046624	sphingolipid transporter activity(GO:0046624)
1.2	27.4	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.2	4.8	GO:0003883	CTP synthase activity(GO:0003883)
1.2	3.5	GO:0030791	arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
1.2	60.0	GO:0019905	syntaxin binding(GO:0019905)
1.2	41.9	GO:0004707	MAP kinase activity(GO:0004707)
1.1	4.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
1.1	11.4	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
1.1	13.7	GO:0043014	alpha-tubulin binding(GO:0043014)
1.1	8.0	GO:0004995	tachykinin receptor activity(GO:0004995)
1.1	8.0	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
1.1	3.4	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
1.1	7.8	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
1.1	26.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.1	5.4	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.1	7.6	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
1.1	7.5	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1	7.5	GO:0016918	retinal binding(GO:0016918)
1.1	35.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
1.1	14.9	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
1.0	99.7	GO:0045296	cadherin binding(GO:0045296)
1.0	23.9	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
1.0	12.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
1.0	23.9	GO:0008378	galactosyltransferase activity(GO:0008378)
1.0	7.8	GO:0015232	heme transporter activity(GO:0015232)
1.0	7.7	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.9	25.5	GO:0004016	adenylate cyclase activity(GO:0004016)
0.9	29.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.9	6.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.9	4.6	GO:0034595	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.9	19.2	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.9	20.5	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.9	281.0	GO:0015631	tubulin binding(GO:0015631)
0.9	11.3	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.9	3.5	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.9	1.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.9	26.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.8	5.1	GO:0030619	U1 snRNA binding(GO:0030619)
0.8	6.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8	2.5	GO:0071568	UFM1 transferase activity(GO:0071568)
0.8	8.2	GO:0005042	netrin receptor activity(GO:0005042)
0.8	5.7	GO:0035254	glutamate receptor binding(GO:0035254)
0.8	4.9	GO:0019107	myristoyltransferase activity(GO:0019107)
0.8	9.7	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.8	8.8	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.8	7.2	GO:0005113	patched binding(GO:0005113)
0.8	4.0	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.8	31.0	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.8	65.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.8	46.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.8	17.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.8	6.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.8	3.1	GO:0051059	NF-kappaB binding(GO:0051059)
0.8	2.3	GO:0047690	aspartyltransferase activity(GO:0047690)
0.8	2.3	GO:0070735	protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.8	3.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.8	6.8	GO:0035925	AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8	1.5	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.8	5.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.8	33.8	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.7	3.7	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7	14.8	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.7	8.8	GO:0048495	Roundabout binding(GO:0048495)
0.7	18.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.7	5.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.7	17.5	GO:0031267	small GTPase binding(GO:0031267)
0.7	7.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.7	10.9	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.7	3.6	GO:0031841	neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.7	4.3	GO:0043531	ADP binding(GO:0043531)
0.7	8.5	GO:0005158	insulin receptor binding(GO:0005158)
0.7	11.4	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.7	283.0	GO:0003712	transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.7	64.0	GO:0022832	voltage-gated channel activity(GO:0022832)
0.7	4.6	GO:0030371	translation repressor activity(GO:0030371)
0.7	235.5	GO:0005096	GTPase activator activity(GO:0005096)
0.7	2.0	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.6	3.9	GO:0004985	opioid receptor activity(GO:0004985)
0.6	9.7	GO:0035064	methylated histone binding(GO:0035064)
0.6	200.5	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.6	8.9	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.6	7.6	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.6	13.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.6	7.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.6	11.1	GO:0033691	sialic acid binding(GO:0033691)
0.6	24.0	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.6	2.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6	3.6	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.6	24.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6	2.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.6	2.4	GO:0004925	prolactin receptor activity(GO:0004925)
0.6	5.4	GO:0008013	beta-catenin binding(GO:0008013)
0.6	2.9	GO:0004122	cystathionine beta-synthase activity(GO:0004122)
0.6	18.7	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.6	194.0	GO:0003924	GTPase activity(GO:0003924)
0.5	11.5	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.5	38.8	GO:0042802	identical protein binding(GO:0042802)
0.5	7.6	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.5	6.4	GO:0005231	extracellular ATP-gated cation channel activity(GO:0004931) excitatory extracellular ligand-gated ion channel activity(GO:0005231) ATP-gated ion channel activity(GO:0035381)
0.5	0.5	GO:0003994	aconitate hydratase activity(GO:0003994)
0.5	1.6	GO:0004788	thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.5	15.7	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.5	8.7	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.5	8.6	GO:0002039	p53 binding(GO:0002039)
0.5	5.3	GO:0015278	calcium-release channel activity(GO:0015278)
0.5	14.1	GO:0005254	chloride channel activity(GO:0005254)
0.5	2.4	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5	4.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.5	11.0	GO:0035591	signaling adaptor activity(GO:0035591)
0.5	4.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.5	3.8	GO:0004849	uridine kinase activity(GO:0004849)
0.5	0.9	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.5	17.3	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.5	3.3	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5	3.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.5	9.3	GO:0097602	cullin family protein binding(GO:0097602)
0.5	12.7	GO:0031490	chromatin DNA binding(GO:0031490)
0.4	405.2	GO:0005509	calcium ion binding(GO:0005509)
0.4	5.3	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4	13.2	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.4	13.0	GO:0044325	ion channel binding(GO:0044325)
0.4	18.9	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.4	1.7	GO:0008488	gamma-glutamyl carboxylase activity(GO:0008488)
0.4	2.9	GO:0035252	UDP-xylosyltransferase activity(GO:0035252)
0.4	4.6	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.4	1.6	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4	5.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.4	2.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.4	4.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4	2.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.4	1.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.4	2.8	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.4	2.8	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.3	5.8	GO:0015026	coreceptor activity(GO:0015026)
0.3	36.7	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.3	2.0	GO:0004997	thyrotropin-releasing hormone receptor activity(GO:0004997)
0.3	9.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	16.5	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.3	34.3	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3	3.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3	4.8	GO:0016018	drug binding(GO:0008144) cyclosporin A binding(GO:0016018)
0.3	0.6	GO:0070883	pre-miRNA binding(GO:0070883)
0.3	1.5	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.3	3.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	6.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	1.5	GO:1990757	anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.3	2.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3	2.6	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.3	3.7	GO:0030544	Hsp70 protein binding(GO:0030544)
0.3	11.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.3	5.8	GO:0051018	protein kinase A binding(GO:0051018)
0.3	4.9	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.3	1.9	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3	3.0	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.3	7.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.2	1.0	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.2	1.7	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2	59.0	GO:0003682	chromatin binding(GO:0003682)
0.2	108.3	GO:0046983	protein dimerization activity(GO:0046983)
0.2	2.6	GO:0043495	protein anchor(GO:0043495)
0.2	1.8	GO:0004994	somatostatin receptor activity(GO:0004994)
0.2	2.7	GO:0070491	repressing transcription factor binding(GO:0070491)
0.2	3.4	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2	1.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2	1.0	GO:0043560	insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2	11.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	3.3	GO:0035497	cAMP response element binding(GO:0035497)
0.2	0.5	GO:0004771	sterol esterase activity(GO:0004771)
0.2	1.6	GO:0036374	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2	2.0	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	396.6	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2	8.4	GO:0000146	microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.2	3.0	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.2	9.0	GO:0008170	N-methyltransferase activity(GO:0008170)
0.2	8.0	GO:0071949	FAD binding(GO:0071949)
0.2	3.0	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.6	GO:0017064	fatty acid amide hydrolase activity(GO:0017064)
0.1	2.1	GO:0016408	C-acyltransferase activity(GO:0016408)
0.1	2.3	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.6	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	4.2	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	3.0	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	0.5	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	13.0	GO:0003690	double-stranded DNA binding(GO:0003690)
0.1	66.0	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.1	0.2	GO:0005521	lamin binding(GO:0005521)
0.1	31.7	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	2.4	GO:0005548	phospholipid transporter activity(GO:0005548)
0.1	0.8	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	1.5	GO:0019213	deacetylase activity(GO:0019213)
0.1	11.1	GO:0005179	hormone activity(GO:0005179)
0.1	0.4	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.1	0.6	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	1.4	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	0.3	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1	0.9	GO:0004568	chitinase activity(GO:0004568)
0.1	12.0	GO:0019901	protein kinase binding(GO:0019901)
0.1	0.8	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.7	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.1	2.9	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.1	0.8	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.6	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	1.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.3	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.1	2.0	GO:0019239	deaminase activity(GO:0019239)
0.1	0.9	GO:0022840	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1	1.8	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	2.2	GO:0030276	clathrin binding(GO:0030276)
0.1	12.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.2	GO:0042164	interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0	1.4	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.8	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.3	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.5	GO:0016836	hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.0	84.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
3.4	26.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
3.1	36.8	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
2.2	65.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
2.0	42.6	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
2.0	44.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
2.0	39.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
1.9	27.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
1.7	74.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
1.7	48.6	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.7	35.0	PID EPHA FWDPATHWAY	EPHA forward signaling
1.6	12.9	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
1.5	42.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
1.4	13.9	PID S1P S1P1 PATHWAY	S1P1 pathway
1.4	28.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
1.3	10.6	PID REELIN PATHWAY	Reelin signaling pathway
1.3	44.9	ST G ALPHA I PATHWAY	G alpha i Pathway
1.3	17.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
1.2	54.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
1.1	37.2	PID ATM PATHWAY	ATM pathway
1.1	22.8	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.0	7.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
1.0	24.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
1.0	3.9	ST ADRENERGIC	Adrenergic Pathway
1.0	15.6	PID RHOA PATHWAY	RhoA signaling pathway
0.9	20.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.9	8.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.8	18.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.8	13.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.8	10.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.8	12.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.8	45.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.7	6.0	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.7	2.9	PID IGF1 PATHWAY	IGF1 pathway
0.7	2.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.7	8.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7	21.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.6	26.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.6	4.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.6	6.6	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.6	21.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.6	7.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.6	1.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.4	13.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.4	6.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.4	6.8	PID ARF 3PATHWAY	Arf1 pathway
0.3	6.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	1.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	10.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	2.8	PID FOXO PATHWAY	FoxO family signaling
0.2	3.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	1.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	3.8	PID NOTCH PATHWAY	Notch signaling pathway
0.1	1.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.0	79.9	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
13.5	202.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
9.9	29.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
7.7	53.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
5.7	51.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
5.7	79.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
5.4	65.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
5.0	5.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
4.4	26.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
3.6	29.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
3.5	38.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
3.4	41.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
3.2	45.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
3.2	19.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
3.0	27.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
2.6	15.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
2.5	27.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.4	24.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
2.3	20.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
2.2	21.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
2.1	8.5	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
2.1	33.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
2.0	37.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
1.9	7.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
1.9	21.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
1.9	17.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
1.9	19.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
1.8	37.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.6	42.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
1.6	11.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.5	14.9	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
1.5	35.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
1.3	44.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
1.2	15.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
1.1	59.0	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
1.1	7.7	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
1.1	35.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
1.1	12.7	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
1.0	5.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.9	2.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.9	1.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.9	28.3	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.8	5.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.8	57.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.8	8.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.8	43.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.8	12.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.7	12.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.7	3.6	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.7	12.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.7	9.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6	2.5	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.6	3.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.6	26.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.6	3.5	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.6	20.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.5	5.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.5	6.0	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.5	7.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.5	18.8	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5	6.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.5	7.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5	5.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.4	12.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.4	12.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.4	15.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.4	4.7	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.4	32.4	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.4	4.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.4	40.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.4	9.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4	4.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.4	4.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3	9.1	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
0.3	21.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	13.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.3	6.6	REACTOME KINESINS	Genes involved in Kinesins
0.3	3.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.3	5.9	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3	4.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3	3.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	12.7	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.2	1.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.2	4.4	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.2	2.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.2	1.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	3.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	4.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	1.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	11.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	5.9	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.2	1.9	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2	1.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	2.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.1	1.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	6.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	4.3	REACTOME MEIOSIS	Genes involved in Meiosis
0.1	1.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	6.0	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.1	1.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	1.0	REACTOME PROTEIN FOLDING	Genes involved in Protein folding