Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for hoxb8a+hoxb8b

Z-value: 1.13

Motif logo

logo of

Transcription factors associated with hoxb8a+hoxb8b

Gene Symbol Gene ID Gene Info
hoxb8b
ENSDARG00000054025 homeobox B8b
hoxb8a
ENSDARG00000056027 homeobox B8a
hoxb8b
ENSDARG00000111056 homeobox B8b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb8bdr11_v1_chr12_+_27117609_271176090.431.4e-05Click!
hoxb8adr11_v1_chr3_+_23687909_236879090.294.9e-03Click!

Activity profile of hoxb8a+hoxb8b motif

Sorted Z-values of hoxb8a+hoxb8b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_39011514 25.09 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr18_+_13792490 20.73 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr2_+_33368414 20.13 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr15_+_4632782 19.43 ENSDART00000156012
si:dkey-35i13.1
si:dkey-35i13.1
chr16_+_10776688 19.42 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr9_+_42066030 16.56 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr18_-_38088099 16.55 ENSDART00000146120
luzp2
leucine zipper protein 2
chr2_-_9646857 16.49 ENSDART00000056901
zgc:153615
zgc:153615
chr1_+_16144615 15.05 ENSDART00000054707
tusc3
tumor suppressor candidate 3
chr8_-_34052019 14.62 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr23_-_11870962 13.39 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr20_+_20672163 12.89 ENSDART00000027758
rtn1b
reticulon 1b
chr18_+_21408794 12.80 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr22_+_18389271 12.34 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr13_-_30027730 11.63 ENSDART00000044009
scdb
stearoyl-CoA desaturase b
chr2_+_47623202 11.32 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr1_-_9277986 11.03 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubn1
ubinuclein 1
chr9_-_23217196 10.82 ENSDART00000083567
kif5c
kinesin family member 5C
chr13_+_23282549 10.14 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr18_+_783936 10.02 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr10_+_23060391 9.80 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr17_+_19626479 9.29 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr3_-_34337969 9.15 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr7_-_69983948 8.96 ENSDART00000185827
KCNIP4
potassium voltage-gated channel interacting protein 4
chr11_+_6819050 8.60 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr20_-_29420713 8.47 ENSDART00000147464
ryr3
ryanodine receptor 3
chr6_+_14949950 8.31 ENSDART00000149202
ENSDART00000149949
pou3f3b
POU class 3 homeobox 3b
chr1_-_23157583 8.08 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr24_-_6898302 8.01 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr14_+_25465346 7.90 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr20_-_19590378 7.77 ENSDART00000152588
baalcb
brain and acute leukemia, cytoplasmic b
chr12_-_11457625 7.61 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr8_-_34051548 7.51 ENSDART00000105204
pbx3b
pre-B-cell leukemia homeobox 3b
chr17_+_15535501 7.51 ENSDART00000002932
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr4_+_13810811 7.47 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr16_+_17389116 7.47 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr24_-_28259127 7.44 ENSDART00000149589
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr12_+_39685485 7.33 ENSDART00000163403
LO017650.1

chr11_-_13341483 7.06 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr25_+_15647750 7.01 ENSDART00000137375
spon1b
spondin 1b
chr19_-_3123963 6.77 ENSDART00000122816
si:ch211-80h18.1
si:ch211-80h18.1
chr1_-_19215336 6.55 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr12_-_3756405 6.51 ENSDART00000150839
fam57bb
family with sequence similarity 57, member Bb
chr8_-_52413032 6.45 ENSDART00000183039
CABZ01070469.1

chr24_+_41915878 6.16 ENSDART00000171523
TMEM200C
transmembrane protein 200C
chr11_-_3959889 5.83 ENSDART00000159683
pbrm1
polybromo 1
chr14_+_6954579 5.74 ENSDART00000060998
nme5
NME/NM23 family member 5
chr13_+_36622100 5.72 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr2_+_37480669 5.66 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr24_+_24461341 5.62 ENSDART00000147658
bhlhe22
basic helix-loop-helix family, member e22
chr21_-_26918901 5.55 ENSDART00000100685
lrfn4a
leucine rich repeat and fibronectin type III domain containing 4a
chr2_+_35240764 5.36 ENSDART00000015827
tnr
tenascin R (restrictin, janusin)
chr9_+_38075851 5.34 ENSDART00000135314
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr11_-_44030962 5.32 ENSDART00000171910
FP016005.1

chr25_+_15647993 5.29 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr5_-_24869213 5.25 ENSDART00000112287
ENSDART00000144635
gas2l1
growth arrest-specific 2 like 1
chr24_+_5840258 5.25 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr7_+_38811800 5.19 ENSDART00000052322
zgc:110699
zgc:110699
chr24_+_24461558 5.12 ENSDART00000182424
bhlhe22
basic helix-loop-helix family, member e22
chr21_+_22878991 5.09 ENSDART00000186399
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr5_-_34185115 5.02 ENSDART00000192771
fibcd1
fibrinogen C domain containing 1
chr15_+_28116129 5.01 ENSDART00000185157
unc119a
unc-119 homolog a (C. elegans)
chr23_+_21479958 4.97 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
si:dkey-1c11.1
chr6_-_18960105 4.95 ENSDART00000185278
ENSDART00000162968
sept9b
septin 9b
chr2_-_10188598 4.90 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr15_-_5467477 4.88 ENSDART00000123839
arrb1
arrestin, beta 1
chr21_-_31241254 4.81 ENSDART00000065365
tpst1l
tyrosylprotein sulfotransferase 1, like
chr7_-_40959867 4.71 ENSDART00000174009
rbm33a
RNA binding motif protein 33a
chr13_+_22316746 4.67 ENSDART00000188968
usp54a
ubiquitin specific peptidase 54a
chr13_-_5569562 4.58 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr19_+_37925616 4.55 ENSDART00000148348
nxph1
neurexophilin 1
chr7_-_31938938 4.54 ENSDART00000132353
bdnf
brain-derived neurotrophic factor
chr2_+_2223837 4.50 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr10_+_26571174 4.48 ENSDART00000148617
ENSDART00000112956
slc9a6b
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr13_-_8776474 4.44 ENSDART00000122371
STPG4
si:ch211-93n23.7
chr9_-_20372977 4.40 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr18_+_10840071 4.34 ENSDART00000014496
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr24_-_40009446 4.33 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr7_+_42460302 4.32 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr21_-_23308286 4.29 ENSDART00000184419
zbtb16a
zinc finger and BTB domain containing 16a
chr7_-_18598661 4.09 ENSDART00000182109
DTX4
si:ch211-119e14.2
chr11_-_3959477 4.06 ENSDART00000045971
pbrm1
polybromo 1
chr18_+_17959681 3.97 ENSDART00000142700
znf423
zinc finger protein 423
chr7_+_13382852 3.91 ENSDART00000166318
dagla
diacylglycerol lipase, alpha
chr4_+_12292274 3.84 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr14_+_35237613 3.81 ENSDART00000163465
ebf3a
early B cell factor 3a
chr6_+_52804267 3.75 ENSDART00000065681
matn4
matrilin 4
chr2_-_54039293 3.64 ENSDART00000166013
abhd8a
abhydrolase domain containing 8a
chr18_-_8857137 3.61 ENSDART00000126331
prrt4
proline-rich transmembrane protein 4
chr23_-_32304650 3.59 ENSDART00000143772
ENSDART00000085642
ENSDART00000188989
dgkaa
diacylglycerol kinase, alpha a
chr11_-_13341051 3.44 ENSDART00000121872
mast3b
microtubule associated serine/threonine kinase 3b
chr12_+_22404108 3.44 ENSDART00000153055
hdlbpb
high density lipoprotein binding protein b
chr21_+_22878834 3.44 ENSDART00000065562
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr5_+_61361815 3.40 ENSDART00000009507
gatsl2
GATS protein-like 2
chr2_+_38608290 3.34 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr4_-_4261673 3.18 ENSDART00000150694
cd9b
CD9 molecule b
chr13_-_5568928 3.07 ENSDART00000192679
meis1b
Meis homeobox 1 b
chr3_-_33574576 3.05 ENSDART00000184881
CR847537.1

chr15_+_8767650 3.01 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr9_-_15789526 2.91 ENSDART00000141318
si:dkey-103d23.3
si:dkey-103d23.3
chr12_-_43428542 2.90 ENSDART00000192266
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr18_+_50890749 2.79 ENSDART00000174109
si:ch1073-450f2.1
si:ch1073-450f2.1
chr3_+_59784632 2.77 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr3_-_16227490 2.74 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr2_-_24962820 2.73 ENSDART00000182767
hltf
helicase-like transcription factor
chr6_+_45347219 2.72 ENSDART00000188240
LO017951.1

chr12_+_38770654 2.69 ENSDART00000155367
kif19
kinesin family member 19
chr10_+_43039947 2.66 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr3_-_16227683 2.61 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr2_+_45068366 2.56 ENSDART00000142175
si:dkey-76d14.2
si:dkey-76d14.2
chr20_-_8443425 2.48 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr1_-_21901589 2.45 ENSDART00000140553
frmpd1a
FERM and PDZ domain containing 1a
chr6_-_53144336 2.44 ENSDART00000154429
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr4_+_7391110 2.43 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr10_+_36026576 2.36 ENSDART00000193786
hmgb1a
high mobility group box 1a
chr20_-_32188897 2.24 ENSDART00000133887
si:ch211-51a19.5
si:ch211-51a19.5
chr13_+_8604710 2.24 ENSDART00000091097
socs5b
suppressor of cytokine signaling 5b
chr4_+_20954929 2.21 ENSDART00000143674
nav3
neuron navigator 3
chr24_+_28953089 2.20 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr17_-_38778826 2.18 ENSDART00000168182
ENSDART00000124041
ENSDART00000136921
dglucy
D-glutamate cyclase
chr4_+_30363474 2.15 ENSDART00000168421
si:dkey-199m13.7
si:dkey-199m13.7
chr21_+_43669943 2.08 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr11_+_23265157 1.97 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr4_-_30362840 1.95 ENSDART00000165929
znf1083
zinc finger protein 1083
chr19_+_12444943 1.91 ENSDART00000135706
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr24_-_7826489 1.83 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr7_-_46777876 1.83 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr23_+_5490854 1.81 ENSDART00000175403
tulp1a
tubby like protein 1a
chr11_+_3281899 1.81 ENSDART00000181012
mmp19
matrix metallopeptidase 19
chr20_+_54274431 1.79 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr12_+_18458502 1.79 ENSDART00000108745
rnf151
ring finger protein 151
chr11_+_36243774 1.75 ENSDART00000023323
zgc:172270
zgc:172270
chr19_-_41518922 1.70 ENSDART00000164483
ENSDART00000062080
chrac1
chromatin accessibility complex 1
chr4_+_21867522 1.64 ENSDART00000140400
acss3
acyl-CoA synthetase short chain family member 3
chr9_+_19529951 1.56 ENSDART00000125416
pknox1.1
pbx/knotted 1 homeobox 1.1
chr20_+_20751425 1.49 ENSDART00000177048
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr5_+_19094153 1.48 ENSDART00000186525
ENSDART00000064752
unc13ba
unc-13 homolog Ba (C. elegans)
chr1_+_55104376 1.41 ENSDART00000150492
aftpha
aftiphilin a
chr1_+_23784905 1.32 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr2_+_3809226 1.31 ENSDART00000147261
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr12_-_28848015 1.29 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr7_-_59159253 1.26 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr17_-_19626357 1.25 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr14_+_36231126 1.21 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr17_-_26507289 1.19 ENSDART00000155616
ccser2a
coiled-coil serine-rich protein 2a
chr1_-_8980665 1.16 ENSDART00000148182
si:ch73-191k20.3
si:ch73-191k20.3
chr15_-_30450898 1.12 ENSDART00000156584
msi2b
musashi RNA-binding protein 2b
chr6_-_53281518 1.08 ENSDART00000157621
rbm5
RNA binding motif protein 5
chr13_+_15581270 1.07 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr4_+_17655872 0.99 ENSDART00000066999
washc3
WASH complex subunit 3
chr5_+_19094462 0.96 ENSDART00000190596
unc13ba
unc-13 homolog Ba (C. elegans)
chr4_-_9909371 0.92 ENSDART00000102656
si:dkey-22l11.6
si:dkey-22l11.6
chr6_-_53143667 0.91 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr1_-_27014872 0.91 ENSDART00000147414
ENSDART00000134032
ENSDART00000192087
ENSDART00000189111
ENSDART00000187348
ENSDART00000187248
cntln
centlein, centrosomal protein
chr24_+_34113424 0.86 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr2_-_9259283 0.77 ENSDART00000133092
st6galnac5a
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr24_+_18948665 0.75 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_-_40959667 0.73 ENSDART00000084070
rbm33a
RNA binding motif protein 33a
chr2_+_10821127 0.72 ENSDART00000145770
ENSDART00000174629
ENSDART00000081094
glmna
glomulin, FKBP associated protein a
chr19_-_27830818 0.72 ENSDART00000131767
papd7
PAP associated domain containing 7
chr10_-_8197049 0.69 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr18_+_34225520 0.68 ENSDART00000126115
v2rl1
vomeronasal 2 receptor, l1
chr19_+_5480327 0.66 ENSDART00000148794
jupb
junction plakoglobin b
chr4_+_54618332 0.66 ENSDART00000171824
si:ch211-227e10.2
si:ch211-227e10.2
chr5_-_32813933 0.63 ENSDART00000050041
ENSDART00000135864
ptpa
protein phosphatase 2 phosphatase activator
chr7_+_31879649 0.62 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr4_-_31311871 0.60 ENSDART00000163681
ENSDART00000168598
si:dkey-43f9.4
si:dkey-43f9.4
chr13_+_30912385 0.58 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr19_-_17303500 0.58 ENSDART00000162355
sf3a3
splicing factor 3a, subunit 3
chr6_-_28345002 0.54 ENSDART00000158955
si:busm1-105l16.2
si:busm1-105l16.2
chr2_-_24603325 0.52 ENSDART00000113356
crtc1a
CREB regulated transcription coactivator 1a
chr8_+_18588551 0.48 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr17_-_8570257 0.48 ENSDART00000154713
ENSDART00000121488
fzd3b
frizzled class receptor 3b
chr11_+_24002503 0.48 ENSDART00000164702
chia.2
chitinase, acidic.2
chr17_+_10501647 0.47 ENSDART00000140391
tyro3
TYRO3 protein tyrosine kinase
chr21_+_22423286 0.46 ENSDART00000133190
capslb
calcyphosine-like b
chr21_-_27338639 0.46 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr6_+_23931236 0.44 ENSDART00000166079
gadd45ab
growth arrest and DNA-damage-inducible, alpha, b
chr3_-_13599482 0.43 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr5_+_31959954 0.41 ENSDART00000142826
myo1hb
myosin IHb
chr8_-_22514918 0.39 ENSDART00000021514
ENSDART00000189272
apex2
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr16_-_31451282 0.37 ENSDART00000192354
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr20_-_2949028 0.29 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cdk19
cyclin-dependent kinase 19
chr1_+_26071869 0.27 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr18_+_27218737 0.24 ENSDART00000111450
plekha7a
pleckstrin homology domain containing, family A member 7a
chr12_-_26406323 0.23 ENSDART00000131896
myoz1b
myozenin 1b
chr10_-_27741793 0.23 ENSDART00000129369
ENSDART00000192440
ENSDART00000189808
ENSDART00000138149
auts2a
si:dkey-33o22.1
autism susceptibility candidate 2a
si:dkey-33o22.1
chr23_-_21534738 0.21 ENSDART00000134587
rcc2
regulator of chromosome condensation 2
chr19_+_28256076 0.19 ENSDART00000133354
irx4b
iroquois homeobox 4b
chr16_-_31451720 0.17 ENSDART00000146886
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr4_+_13428993 0.16 ENSDART00000067151
si:dkey-39a18.1
si:dkey-39a18.1
chr11_-_2838699 0.16 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr23_-_30960506 0.11 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr7_+_31879986 0.07 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr1_+_51191049 0.07 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr4_+_50463619 0.02 ENSDART00000150365
BX663613.1

chr4_+_43408004 0.01 ENSDART00000150476
si:dkeyp-53e4.2
si:dkeyp-53e4.2

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb8a+hoxb8b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 20.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
3.1 12.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
2.9 11.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
2.9 8.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.7 16.5 GO:0035332 positive regulation of hippo signaling(GO:0035332)
2.6 20.7 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
2.4 9.8 GO:0006843 mitochondrial citrate transport(GO:0006843)
1.9 5.7 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.8 12.8 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
1.5 10.8 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.2 4.9 GO:0060300 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
1.2 8.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.1 5.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.1 10.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.0 19.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
1.0 3.9 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.9 15.1 GO:0015693 magnesium ion transport(GO:0015693)
0.9 4.3 GO:0046677 response to antibiotic(GO:0046677)
0.6 5.0 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.6 7.5 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.6 4.8 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.6 9.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.6 9.0 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.4 1.3 GO:0007414 axonal defasciculation(GO:0007414)
0.4 2.4 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.4 4.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 4.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 3.0 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.4 1.8 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 4.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.3 2.5 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 3.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.3 2.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 5.2 GO:0051764 actin crosslink formation(GO:0051764)
0.3 1.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3 10.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 8.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.3 4.9 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 4.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.6 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.2 7.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 13.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 6.1 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 1.7 GO:0031579 membrane raft assembly(GO:0001765) membrane raft organization(GO:0031579) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.2 9.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.2 4.3 GO:0006828 manganese ion transport(GO:0006828)
0.2 8.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.2 2.2 GO:0072576 liver morphogenesis(GO:0072576)
0.2 3.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 0.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.9 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 2.4 GO:0009409 response to cold(GO:0009409)
0.1 11.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 3.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 2.2 GO:0006536 glutamate metabolic process(GO:0006536)
0.1 0.7 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.1 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 4.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 2.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.8 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 4.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 9.7 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 2.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.5 GO:0006032 chitin catabolic process(GO:0006032)
0.0 1.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 24.3 GO:0007420 brain development(GO:0007420)
0.0 3.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.7 GO:0006497 protein lipidation(GO:0006497)
0.0 7.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.5 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.0 1.5 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.5 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 2.2 GO:0031016 pancreas development(GO:0031016)
0.0 0.5 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 2.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.6 GO:0051297 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 10.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.4 5.7 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
1.2 9.9 GO:0016586 RSC complex(GO:0016586)
1.2 8.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.1 15.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.6 7.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 5.0 GO:0045171 intercellular bridge(GO:0045171)
0.4 20.8 GO:0016342 catenin complex(GO:0016342)
0.3 1.3 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.3 3.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 1.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 4.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 1.0 GO:0071203 WASH complex(GO:0071203)
0.2 13.5 GO:0005871 kinesin complex(GO:0005871)
0.1 4.6 GO:0005844 polysome(GO:0005844)
0.1 1.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 9.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 4.9 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 7.5 GO:0032432 actin filament bundle(GO:0032432)
0.1 9.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.8 GO:0005869 dynactin complex(GO:0005869)
0.1 2.4 GO:0043195 terminal bouton(GO:0043195)
0.1 12.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 7.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 4.3 GO:0034703 cation channel complex(GO:0034703)
0.1 19.1 GO:0030424 axon(GO:0030424)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.2 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 2.4 GO:0005861 troponin complex(GO:0005861)
0.1 5.2 GO:0005884 actin filament(GO:0005884)
0.1 3.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 4.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 6.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 10.8 GO:0005739 mitochondrion(GO:0005739)
0.0 16.7 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.6 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.9 19.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.7 8.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
1.4 20.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.9 2.7 GO:0019777 Atg12 transferase activity(GO:0019777)
0.9 4.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 5.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 4.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.6 2.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.5 12.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.5 10.1 GO:0008143 poly(A) binding(GO:0008143)
0.4 8.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 1.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 13.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 4.5 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.4 8.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 10.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 3.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 2.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 5.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 4.5 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.3 7.4 GO:0016208 AMP binding(GO:0016208)
0.3 7.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 20.8 GO:0045296 cadherin binding(GO:0045296)
0.2 5.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 4.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 32.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 3.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 3.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 4.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 19.2 GO:0003924 GTPase activity(GO:0003924)
0.0 2.2 GO:0009975 cyclase activity(GO:0009975)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 14.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 8.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 6.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 11.7 GO:0003682 chromatin binding(GO:0003682)
0.0 2.1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 4.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 7.2 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.0 GO:0005125 cytokine activity(GO:0005125)
0.0 1.7 GO:0060090 binding, bridging(GO:0060090)
0.0 15.3 GO:0003723 RNA binding(GO:0003723)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 10.0 GO:0003779 actin binding(GO:0003779)
0.0 20.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 9.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 8.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 20.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.9 20.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 8.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.4 9.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 3.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 2.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 12.7 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 1.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 3.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives