Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for hoxc12a+hoxc12b

Z-value: 1.09

Motif logo

logo of

Transcription factors associated with hoxc12a+hoxc12b

Gene Symbol Gene ID Gene Info
hoxc12a
ENSDARG00000070352 homeobox C12a
hoxc12b
ENSDARG00000103133 homeobox C12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc12bdr11_v1_chr11_+_2172335_21723350.103.6e-01Click!
hoxc12adr11_v1_chr23_+_36063599_36063599-0.065.8e-01Click!

Activity profile of hoxc12a+hoxc12b motif

Sorted Z-values of hoxc12a+hoxc12b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_35691889 22.25 ENSDART00000074685
glrbb
glycine receptor, beta b
chr21_-_19018455 19.95 ENSDART00000080256
nefma
neurofilament, medium polypeptide a
chr21_+_13861589 19.95 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr25_-_11057753 17.46 ENSDART00000186551
sv2bb
synaptic vesicle glycoprotein 2Bb
chr23_-_4855122 14.72 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr10_+_21776911 13.71 ENSDART00000163077
ENSDART00000186093
pcdh1g22
protocadherin 1 gamma 22
chr1_-_26782573 13.04 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr8_-_14049404 12.94 ENSDART00000093117
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr19_-_10243148 12.80 ENSDART00000148073
shisa7b
shisa family member 7
chr1_-_8101495 12.28 ENSDART00000161938
si:dkeyp-9d4.3
si:dkeyp-9d4.3
chr12_+_27129659 11.03 ENSDART00000076161
hoxb5b
homeobox B5b
chr21_-_4032650 10.87 ENSDART00000151648
ntng2b
netrin g2b
chr23_-_12015139 10.63 ENSDART00000110627
ENSDART00000193988
ENSDART00000184528
si:dkey-178k16.1
si:dkey-178k16.1
chr15_-_19250543 10.34 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr6_+_49412754 9.06 ENSDART00000027398
kcna2a
potassium voltage-gated channel, shaker-related subfamily, member 2a
chr25_+_21176937 8.94 ENSDART00000163751
ENSDART00000188930
ENSDART00000187155
erc1a
ELKS/RAB6-interacting/CAST family member 1a
chr10_+_21660447 8.47 ENSDART00000164519
pcdh1g3
protocadherin 1 gamma 3
chr14_+_32022272 8.31 ENSDART00000105760
zic6
zic family member 6
chr23_-_39849155 7.44 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr13_-_24447332 7.18 ENSDART00000043004
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_-_23996133 7.18 ENSDART00000173761
si:dkey-183c6.8
si:dkey-183c6.8
chr20_-_47422469 7.16 ENSDART00000021341
kif3ca
kinesin family member 3Ca
chr25_-_7999756 7.15 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr21_+_20715020 7.10 ENSDART00000015224
gadd45gb.1
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr23_-_12014931 7.07 ENSDART00000134652
si:dkey-178k16.1
si:dkey-178k16.1
chr1_-_22834824 7.03 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr24_-_6898302 7.02 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr19_+_26718074 6.91 ENSDART00000134455
zgc:100906
zgc:100906
chr2_-_39759059 6.89 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr24_-_40009446 6.82 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr14_+_45883687 6.75 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr4_+_20318127 6.72 ENSDART00000028856
ENSDART00000132909
cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr3_-_27868183 6.53 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr7_-_32833153 6.39 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr10_-_31805923 6.39 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr24_-_38374744 6.29 ENSDART00000007208
lrrc4bb
leucine rich repeat containing 4Bb
chr18_-_2433011 6.27 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr25_-_18002937 6.18 ENSDART00000149696
cep290
centrosomal protein 290
chr5_-_21065094 6.08 ENSDART00000143785
si:dkey-13n15.2
si:dkey-13n15.2
chr25_+_7670683 6.01 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr20_-_44576949 6.01 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr14_-_48348973 5.98 ENSDART00000185822
CABZ01080056.1

chr23_-_28025943 5.92 ENSDART00000181146
sp5l
Sp5 transcription factor-like
chr5_+_36611128 5.85 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr11_+_42730639 5.56 ENSDART00000165297
zgc:194981
zgc:194981
chr5_-_69499486 5.48 ENSDART00000023983
ENSDART00000180293
psat1
phosphoserine aminotransferase 1
chr7_+_59739164 5.28 ENSDART00000110412
gpr78b
G protein-coupled receptor 78b
chr10_+_15967643 5.25 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr18_+_31280984 5.17 ENSDART00000170285
ENSDART00000150608
ENSDART00000159720
def8
differentially expressed in FDCP 8 homolog (mouse)
chr7_-_43840418 4.93 ENSDART00000174592
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_-_18830722 4.89 ENSDART00000165330
ENSDART00000165698
pbx1a
pre-B-cell leukemia homeobox 1a
chr9_-_10145795 4.86 ENSDART00000004745
ENSDART00000143295
hnmt
histamine N-methyltransferase
chr6_-_53334259 4.66 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr13_+_29925397 4.60 ENSDART00000123482
cuedc2
CUE domain containing 2
chr15_-_20412286 4.53 ENSDART00000008589
chp2
calcineurin-like EF-hand protein 2
chr6_-_28943056 4.49 ENSDART00000065138
tbc1d23
TBC1 domain family, member 23
chr4_-_13156971 4.44 ENSDART00000182164
grip1
glutamate receptor interacting protein 1
chr25_-_18002498 4.36 ENSDART00000158688
cep290
centrosomal protein 290
chr5_-_32489796 4.33 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr15_-_14552101 4.20 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr3_+_24190207 4.16 ENSDART00000034762
prr15la
proline rich 15-like a
chr12_-_48552716 4.13 ENSDART00000063438
LO017829.1
Danio rerio testis expressed 47 (tex47), mRNA.
chr5_-_51819027 3.98 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr6_+_49551614 3.75 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr11_+_43751263 3.74 ENSDART00000163843
zgc:153431
zgc:153431
chr7_+_27898091 3.56 ENSDART00000186451
ENSDART00000173510
tub
tubby bipartite transcription factor
chr8_-_19649617 3.54 ENSDART00000189033
fam78bb
family with sequence similarity 78, member B b
chr11_-_37717709 3.44 ENSDART00000177280
yod1
YOD1 deubiquitinase
chr16_+_5184402 3.36 ENSDART00000156685
soga3a
SOGA family member 3a
chr7_+_29167744 3.30 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr18_+_18000887 3.24 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr3_+_36284986 3.05 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr1_-_22370660 3.04 ENSDART00000127506
si:ch73-380n15.2
si:ch73-380n15.2
chr1_+_31019165 3.02 ENSDART00000102210
itga6b
integrin, alpha 6b
chr1_+_36437585 2.97 ENSDART00000189182
pou4f2
POU class 4 homeobox 2
chr15_+_5132439 2.94 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr23_+_23658474 2.91 ENSDART00000162838
agrn
agrin
chr9_-_38399432 2.89 ENSDART00000148268
znf142
zinc finger protein 142
chr2_-_37134169 2.89 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr15_-_6863150 2.86 ENSDART00000153815
meis3
myeloid ecotropic viral integration site 3
chr6_-_14038804 2.84 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr9_+_22634073 2.70 ENSDART00000181822
etv5a
ets variant 5a
chr5_-_31856681 2.68 ENSDART00000187817
pkn3
protein kinase N3
chr1_-_22803147 2.67 ENSDART00000086867
tapt1b
transmembrane anterior posterior transformation 1b
chr21_-_25618175 2.44 ENSDART00000133512
fosl1b
FOS-like antigen 1b
chr16_-_31452416 2.43 ENSDART00000140880
ENSDART00000008297
ENSDART00000147373
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr15_-_23942861 2.34 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr13_+_39182099 2.32 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr6_+_40775800 2.26 ENSDART00000085090
si:ch211-157b11.8
si:ch211-157b11.8
chr16_+_38659475 2.24 ENSDART00000023238
emc2
ER membrane protein complex subunit 2
chr1_-_7894255 2.23 ENSDART00000167126
ENSDART00000145460
radil
Ras association and DIL domains
chr13_-_18119696 2.17 ENSDART00000148125
washc2c
WASH complex subunit 2C
chr6_-_53281518 2.15 ENSDART00000157621
rbm5
RNA binding motif protein 5
chr8_+_52442785 2.12 ENSDART00000189958
zgc:77112
zgc:77112
chr22_+_15308526 2.08 ENSDART00000188280
CU104797.1

chr15_-_39820491 2.06 ENSDART00000097134
robo1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr16_-_6205790 2.05 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr6_-_13709591 2.04 ENSDART00000151771
chpfb
chondroitin polymerizing factor b
chr2_+_30103285 2.02 ENSDART00000019417
dnajb6a
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr3_+_23707691 2.00 ENSDART00000025449
hoxb5a
homeobox B5a
chr20_+_38837238 2.00 ENSDART00000061334
ift172
intraflagellar transport 172
chr3_-_48612078 1.99 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr6_-_54816567 1.98 ENSDART00000150079
tnni1b
troponin I type 1b (skeletal, slow)
chrM_+_3803 1.96 ENSDART00000093596
mt-nd1
NADH dehydrogenase 1, mitochondrial
chr15_+_29116063 1.94 ENSDART00000016112
ENSDART00000153609
ENSDART00000155630
capns1b
calpain, small subunit 1 b
chr13_+_3880882 1.94 ENSDART00000169595
timm23b
translocase of inner mitochondrial membrane 23 homolog b (yeast)
chr5_+_17624463 1.93 ENSDART00000183869
ENSDART00000081064
fbrsl1
fibrosin-like 1
chr10_-_15910974 1.91 ENSDART00000148169
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr9_-_29039506 1.84 ENSDART00000100744
tmem177
transmembrane protein 177
chr2_+_54696042 1.84 ENSDART00000074270
ankrd12
ankyrin repeat domain 12
chr23_+_36115541 1.81 ENSDART00000130090
hoxc6a
homeobox C6a
chr15_+_44093286 1.79 ENSDART00000114352
zgc:112998
zgc:112998
chr4_-_28958601 1.77 ENSDART00000111294
zgc:174315
zgc:174315
chr4_-_23082985 1.72 ENSDART00000133644
magi2a
membrane associated guanylate kinase, WW and PDZ domain containing 2a
chr11_-_26832685 1.71 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr20_+_27240388 1.68 ENSDART00000123950
si:dkey-85n7.6
si:dkey-85n7.6
chr23_-_19434199 1.53 ENSDART00000132543
klhdc8b
kelch domain containing 8B
chr11_-_18557929 1.50 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
dido1
death inducer-obliterator 1
chr3_-_18737126 1.49 ENSDART00000055767
e4f1
E4F transcription factor 1
chr25_+_17920668 1.48 ENSDART00000093358
borcs5
BLOC-1 related complex subunit 5
chr21_-_4539899 1.47 ENSDART00000112460
dolk
dolichol kinase
chr6_-_34838397 1.45 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr20_+_34671386 1.44 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr13_-_9875538 1.42 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr5_-_31857345 1.41 ENSDART00000112546
pkn3
protein kinase N3
chr13_-_32577386 1.40 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr4_-_73520581 1.34 ENSDART00000171513
si:ch73-266f23.1
si:ch73-266f23.1
chr14_-_32866351 1.33 ENSDART00000166133
ENSDART00000172545
ube2a
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr21_+_13128180 1.28 ENSDART00000081426
odf2a
outer dense fiber of sperm tails 2a
chr24_+_21540842 1.26 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr6_-_9236309 1.22 ENSDART00000160397
ENSDART00000164603
iqcb1
IQ motif containing B1
chr17_-_23727978 1.21 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr3_+_59851537 1.20 ENSDART00000180997
CU693479.1

chr7_-_23873173 1.20 ENSDART00000101408
zgc:162171
zgc:162171
chr2_+_31330358 1.17 ENSDART00000178066
clul1
clusterin-like 1 (retinal)
chr20_-_19530751 1.15 ENSDART00000148574
eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr2_-_37874647 1.14 ENSDART00000039386
zgc:66427
zgc:66427
chr24_-_17029374 1.12 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr21_-_22357985 1.10 ENSDART00000101751
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr22_-_31517300 1.10 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr2_-_22966076 1.06 ENSDART00000143412
ENSDART00000146014
ENSDART00000183443
ENSDART00000191056
ENSDART00000183539
sap130b
Sin3A-associated protein b
chr7_+_30240791 1.01 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr16_-_47426482 0.98 ENSDART00000148631
ENSDART00000149723
sept7b
septin 7b
chr4_-_69127091 0.98 ENSDART00000136092
si:ch211-209j12.3
si:ch211-209j12.3
chr12_-_28910419 0.92 ENSDART00000153278
ENSDART00000152937
CCDC189
si:ch73-81k8.2
chr15_-_28262632 0.89 ENSDART00000134601
ENSDART00000175022
prpf8
pre-mRNA processing factor 8
chr10_-_36825984 0.88 ENSDART00000111104
phf12a
PHD finger protein 12a
chr24_-_24797455 0.85 ENSDART00000138741
pde7a
phosphodiesterase 7A
chr17_+_49500820 0.84 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr5_-_54395488 0.77 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr12_-_26851726 0.74 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr4_-_30712588 0.74 ENSDART00000142393
si:dkey-16p19.5
si:dkey-16p19.5
chr15_-_2754056 0.74 ENSDART00000129380
ppp5c
protein phosphatase 5, catalytic subunit
chr13_-_3351708 0.70 ENSDART00000042875
si:ch73-193i2.2
si:ch73-193i2.2
chr10_-_20357013 0.69 ENSDART00000080143
sfrp1b
secreted frizzled-related protein 1b
chr19_+_26640096 0.68 ENSDART00000067793
ints3
integrator complex subunit 3
chr3_+_28953274 0.66 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr22_-_10440688 0.65 ENSDART00000111962
nol8
nucleolar protein 8
chr2_+_23039041 0.62 ENSDART00000056921
csnk1g2a
casein kinase 1, gamma 2a
chr1_-_34612613 0.62 ENSDART00000004361
klf5a
Kruppel-like factor 5a
chr18_-_31105391 0.58 ENSDART00000039495
pdcd5
programmed cell death 5
chr14_-_26425416 0.56 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr5_+_51909740 0.55 ENSDART00000162541
thbs4a
thrombospondin 4a
chr24_-_21913426 0.55 ENSDART00000081178
c1qtnf9
C1q and TNF related 9
chr6_-_28222592 0.53 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr6_+_52869892 0.48 ENSDART00000146143
si:dkeyp-3f10.16
si:dkeyp-3f10.16
chr20_+_48803248 0.48 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr3_-_40254634 0.47 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr22_+_17192767 0.40 ENSDART00000130810
ENSDART00000183006
atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
chr6_+_2174082 0.39 ENSDART00000073936
acvr1bb
activin A receptor type 1Bb
chr25_-_35996141 0.38 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr9_+_44034790 0.38 ENSDART00000166110
ENSDART00000176954
itga4
integrin alpha 4
chr22_+_10440991 0.36 ENSDART00000064805
cenpp
centromere protein P
chr14_-_31060082 0.29 ENSDART00000111601
ENSDART00000161113
mbnl3
muscleblind-like splicing regulator 3
chr7_-_30624435 0.20 ENSDART00000173828
rnf111
ring finger protein 111
chr9_-_9242777 0.19 ENSDART00000021191
u2af1
U2 small nuclear RNA auxiliary factor 1
chr17_+_21295132 0.18 ENSDART00000103845
eno4
enolase family member 4
chr13_+_8892784 0.13 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr5_+_32490238 0.12 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr10_+_31222433 0.12 ENSDART00000185080
tmem218
transmembrane protein 218
chr14_-_36863432 0.12 ENSDART00000158052
rnf130
ring finger protein 130
chr12_+_46696867 0.10 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exoc7
exocyst complex component 7
chr20_-_23657304 0.07 ENSDART00000016913
cbr4
carbonyl reductase 4
chr3_-_10749691 0.07 ENSDART00000183088
CU210890.1

chr22_+_17286841 0.05 ENSDART00000133176
FAM163A
si:dkey-171o17.8
chr12_-_11560794 0.02 ENSDART00000149098
ENSDART00000169975
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc12a+hoxc12b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 21.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.3 6.9 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.8 5.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.8 10.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
1.6 4.9 GO:0001692 histamine metabolic process(GO:0001692)
1.5 4.5 GO:1990403 embryonic brain development(GO:1990403)
1.5 22.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
1.4 6.8 GO:0046677 response to antibiotic(GO:0046677)
1.3 6.7 GO:0014896 muscle hypertrophy(GO:0014896)
1.3 11.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.3 6.5 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
1.0 2.9 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.9 2.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.9 3.4 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.8 11.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.8 4.9 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.8 8.9 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.8 6.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.8 7.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.8 9.1 GO:0030431 sleep(GO:0030431)
0.7 2.0 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.6 2.9 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.6 4.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 1.5 GO:1902803 regulation of synaptic vesicle transport(GO:1902803)
0.5 1.4 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.5 19.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.5 4.7 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.4 6.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.4 10.9 GO:0070831 basement membrane assembly(GO:0070831)
0.4 6.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.3 4.4 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.3 2.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.3 2.1 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.3 3.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 2.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 33.3 GO:0006836 neurotransmitter transport(GO:0006836)
0.2 7.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 14.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 5.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 2.8 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 3.0 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 1.2 GO:0036372 opsin transport(GO:0036372)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.7 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 4.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 2.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 4.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.1 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 1.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 22.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.1 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 8.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 3.6 GO:0061512 protein localization to cilium(GO:0061512)
0.1 8.3 GO:0021510 spinal cord development(GO:0021510)
0.1 2.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 6.0 GO:0010107 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.1 0.7 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 14.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 0.4 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 3.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 2.9 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 13.6 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 3.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.7 GO:0043113 receptor clustering(GO:0043113)
0.0 4.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 2.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.9 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.3 GO:0016574 histone ubiquitination(GO:0016574)
0.0 2.0 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.7 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:0030878 thyroid gland development(GO:0030878)
0.0 5.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 3.4 GO:0010506 regulation of autophagy(GO:0010506)
0.0 8.8 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 7.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 3.0 GO:0021782 glial cell development(GO:0021782)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.1 GO:1901655 cellular response to ketone(GO:1901655)
0.0 1.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.4 GO:0032924 activin receptor signaling pathway(GO:0032924)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 20.0 GO:0005883 neurofilament(GO:0005883)
1.0 10.5 GO:0034451 centriolar satellite(GO:0034451)
0.9 4.5 GO:0071203 WASH complex(GO:0071203)
0.7 11.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.7 9.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.6 6.4 GO:0030904 retromer complex(GO:0030904)
0.5 10.9 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.4 6.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 3.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 1.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.3 2.0 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.3 8.9 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.3 6.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 17.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 1.3 GO:0033503 HULC complex(GO:0033503)
0.3 3.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 19.9 GO:0030141 secretory granule(GO:0030141)
0.2 2.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 2.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 5.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 9.2 GO:0005871 kinesin complex(GO:0005871)
0.1 2.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 7.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 6.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 22.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 4.9 GO:0016342 catenin complex(GO:0016342)
0.1 1.9 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 14.4 GO:0030424 axon(GO:0030424)
0.1 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 4.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.0 GO:0005861 troponin complex(GO:0005861)
0.0 2.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.9 GO:0008305 integrin complex(GO:0008305)
0.0 1.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.7 GO:0005769 early endosome(GO:0005769)
0.0 38.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 4.9 GO:0005929 cilium(GO:0005929)
0.0 6.3 GO:0045202 synapse(GO:0045202)
0.0 3.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 3.8 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 22.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.3 6.9 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.4 6.8 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 14.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.0 3.0 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
1.0 7.0 GO:0030274 LIM domain binding(GO:0030274)
0.8 7.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.8 7.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.8 4.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.5 19.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 8.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.5 6.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.4 12.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 6.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 1.7 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.4 12.0 GO:0008483 transaminase activity(GO:0008483)
0.4 2.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 4.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 7.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 4.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 4.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 1.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.3 0.9 GO:0030623 U5 snRNA binding(GO:0030623)
0.2 2.2 GO:0032977 membrane insertase activity(GO:0032977)
0.2 2.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 2.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 2.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 6.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 5.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 9.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 3.6 GO:0043236 laminin binding(GO:0043236)
0.2 4.1 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 7.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.1 GO:2001069 glycogen binding(GO:2001069)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 5.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 2.2 GO:0051020 GTPase binding(GO:0051020)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 7.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 4.9 GO:0045296 cadherin binding(GO:0045296)
0.1 1.9 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.1 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 7.2 GO:0015293 symporter activity(GO:0015293)
0.0 6.1 GO:0000149 SNARE binding(GO:0000149)
0.0 1.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 3.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 3.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 16.3 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 10.7 GO:0008289 lipid binding(GO:0008289)
0.0 18.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 5.7 GO:0003924 GTPase activity(GO:0003924)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 4.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 8.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 5.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.5 6.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 7.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 4.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 10.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 2.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 3.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination