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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxc13b+hoxd13a

Z-value: 1.18

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Transcription factors associated with hoxc13b+hoxd13a

Gene Symbol Gene ID Gene Info
hoxd13a
ENSDARG00000059256 homeobox D13a
hoxc13b
ENSDARG00000113877 homeobox C13b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc13bdr11_v1_chr11_+_2156430_2156430-0.595.8e-10Click!
hoxd13adr11_v1_chr9_-_1990323_19903230.188.8e-02Click!

Activity profile of hoxc13b+hoxd13a motif

Sorted Z-values of hoxc13b+hoxd13a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22637515 14.19 ENSDART00000158698
si:dkey-112a7.5
si:dkey-112a7.5
chr22_-_24297510 13.22 ENSDART00000163297
si:ch211-117l17.6
si:ch211-117l17.6
chr12_+_13256415 12.55 ENSDART00000144542
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr17_-_8886735 12.36 ENSDART00000121997
nkl.3
NK-lysin tandem duplicate 3
chr17_+_2549503 12.14 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr20_+_26683933 11.53 ENSDART00000139852
ENSDART00000077751
foxq1b
forkhead box Q1b
chr17_+_42274825 11.02 ENSDART00000020156
pax1a
paired box 1a
chr1_+_54650048 10.59 ENSDART00000141207
si:ch211-202h22.7
si:ch211-202h22.7
chr9_-_33081978 10.33 ENSDART00000100918
zgc:172053
zgc:172053
chr3_-_43872889 10.08 ENSDART00000170553
mslna
mesothelin a
chr1_-_59243542 9.61 ENSDART00000163021
mvb12a
multivesicular body subunit 12A
chr9_-_33063083 9.55 ENSDART00000048550
si:ch211-125e6.5
si:ch211-125e6.5
chr2_-_48196092 9.50 ENSDART00000139944
snorc
secondary ossification center associated regulator of chondrocyte maturation
chr1_+_45056371 8.57 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr17_-_37395460 8.56 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr2_+_37295088 8.53 ENSDART00000056519
gpr160
G protein-coupled receptor 160
chr18_-_48547564 8.44 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr24_-_40668208 8.39 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr4_-_77551860 8.28 ENSDART00000188176
AL935186.6

chr20_-_34127415 8.23 ENSDART00000010028
ptgs2b
prostaglandin-endoperoxide synthase 2b
chr10_+_35347993 8.17 ENSDART00000131350
si:dkey-259j3.5
si:dkey-259j3.5
chr25_+_29160102 8.14 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr14_+_10450216 8.11 ENSDART00000134814
cysltr1
cysteinyl leukotriene receptor 1
chr6_-_8360918 7.92 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr9_-_33081781 7.90 ENSDART00000165748
zgc:172053
zgc:172053
chr25_-_3867990 7.84 ENSDART00000075663
cracr2b
calcium release activated channel regulator 2B
chr9_-_23990416 7.79 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr24_-_40667800 7.68 ENSDART00000169315
smyhc1
slow myosin heavy chain 1
chr19_+_20778011 7.49 ENSDART00000024208
nutf2l
nuclear transport factor 2, like
chr15_-_35960250 7.23 ENSDART00000186765
col4a4
collagen, type IV, alpha 4
chr21_-_35419486 7.12 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr4_+_55758103 7.03 ENSDART00000185964
CT583728.23

chr18_+_48428713 6.97 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr13_-_34862452 6.88 ENSDART00000134573
ENSDART00000047552
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr12_-_30523216 6.58 ENSDART00000152896
ENSDART00000153191
plekhs1
pleckstrin homology domain containing, family S member 1
chr1_+_58282449 6.58 ENSDART00000131475
si:dkey-222h21.7
si:dkey-222h21.7
chr20_-_38758797 6.58 ENSDART00000061394
trim54
tripartite motif containing 54
chr22_+_24645325 6.50 ENSDART00000159531
lpar3
lysophosphatidic acid receptor 3
chr9_-_9992697 6.44 ENSDART00000123415
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr1_-_681116 6.43 ENSDART00000165894
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr25_+_34014523 6.23 ENSDART00000182856
anxa2a
annexin A2a
chr16_-_12060770 6.22 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
si:ch211-69g19.2
chr9_-_33062891 6.22 ENSDART00000161182
si:ch211-125e6.5
si:ch211-125e6.5
chr18_+_2228737 6.16 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr16_+_50969248 5.97 ENSDART00000172068
si:dkeyp-97a10.2
si:dkeyp-97a10.2
chr25_+_31277415 5.92 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr16_+_33144306 5.84 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr9_+_23770666 5.76 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr6_+_49771626 5.69 ENSDART00000134207
ctsz
cathepsin Z
chr6_+_49771372 5.68 ENSDART00000063251
ctsz
cathepsin Z
chr24_+_21621654 5.55 ENSDART00000002595
rpl21
ribosomal protein L21
chr4_-_20118468 5.53 ENSDART00000078587
si:dkey-159a18.1
si:dkey-159a18.1
chr16_+_33143503 5.33 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_37087583 5.16 ENSDART00000049900
tagln2
transgelin 2
chr25_+_31276842 5.11 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr24_-_40774028 5.09 ENSDART00000166578
CU633479.2

chr16_+_33144112 5.04 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_57480014 5.02 ENSDART00000135520
si:ch211-202f5.3
si:ch211-202f5.3
chr14_+_2487672 5.00 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr10_+_26612321 4.98 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr6_-_39764995 4.95 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr10_+_24690534 4.89 ENSDART00000079549
tpte
transmembrane phosphatase with tensin homology
chr3_-_25268751 4.88 ENSDART00000139423
mgat3a
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr4_-_74028161 4.87 ENSDART00000174062
LO018205.1

chr16_-_12060488 4.86 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr16_+_35594670 4.75 ENSDART00000163275
si:ch211-1i11.3
si:ch211-1i11.3
chr9_-_42730672 4.64 ENSDART00000136728
fkbp7
FK506 binding protein 7
chr17_+_20607487 4.64 ENSDART00000154123
si:ch73-288o11.5
si:ch73-288o11.5
chr24_-_25166416 4.64 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr18_-_35459605 4.56 ENSDART00000135691
itpkcb
inositol-trisphosphate 3-kinase Cb
chr16_-_36099492 4.52 ENSDART00000180905
CU499336.2

chr7_+_22688781 4.42 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr16_-_21038015 4.40 ENSDART00000059239
snx10b
sorting nexin 10b
chr4_-_26413391 4.39 ENSDART00000145955
b4galnt3a
beta-1,4-N-acetyl-galactosaminyl transferase 3a
chr9_-_1965727 4.37 ENSDART00000082354
hoxd9a
homeobox D9a
chr5_-_67365750 4.30 ENSDART00000062359
unga
uracil DNA glycosylase a
chr2_-_36914281 4.25 ENSDART00000008322
si:dkey-193b15.5
si:dkey-193b15.5
chr21_+_11503212 4.16 ENSDART00000146701
si:dkey-184p9.7
si:dkey-184p9.7
chr2_+_48282590 4.14 ENSDART00000035338
lpar5a
lysophosphatidic acid receptor 5a
chr24_-_35561672 4.14 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr4_-_30249792 4.05 ENSDART00000151833
ENSDART00000137564
ENSDART00000168249
si:dkey-265e15.2
si:dkey-265e15.2
chr18_-_43866001 4.05 ENSDART00000150218
treh
trehalase (brush-border membrane glycoprotein)
chr12_-_34435604 3.99 ENSDART00000115088
birc5a
baculoviral IAP repeat containing 5a
chr14_+_26247319 3.89 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr4_-_26095755 3.85 ENSDART00000100611
ENSDART00000191266
si:ch211-244b2.3
si:ch211-244b2.3
chr19_-_25081711 3.84 ENSDART00000058513
xkr8.3
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3
chr7_+_17861489 3.81 ENSDART00000173860
eml3
echinoderm microtubule associated protein like 3
chr8_-_12432604 3.80 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
traf1
TNF receptor-associated factor 1
chr14_+_21699129 3.76 ENSDART00000073707
stx3a
syntaxin 3A
chr9_+_23714406 3.76 ENSDART00000189445
gypc
glycophorin C (Gerbich blood group)
chr20_+_23238833 3.74 ENSDART00000074167
ociad2
OCIA domain containing 2
chr22_+_35205968 3.73 ENSDART00000150467
tsc22d2
TSC22 domain family 2
chr6_+_48206535 3.67 ENSDART00000075172
cttnbp2nla
CTTNBP2 N-terminal like a
chr5_-_67365006 3.67 ENSDART00000136116
unga
uracil DNA glycosylase a
chr6_+_34028532 3.62 ENSDART00000155827
si:ch73-185c24.2
si:ch73-185c24.2
chr22_+_18477934 3.62 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr15_-_41457898 3.54 ENSDART00000188847
nlrc9
NLR family CARD domain containing 9
chr25_+_24616717 3.53 ENSDART00000089113
abtb2b
ankyrin repeat and BTB (POZ) domain containing 2b
chr12_+_17154655 3.52 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr20_+_18993452 3.47 ENSDART00000025509
tdh
L-threonine dehydrogenase
chr22_-_22164338 3.43 ENSDART00000183840
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr2_-_36599044 3.38 ENSDART00000161829
tradv23.3.8
T-cell receptor alpha/delta variable 23.3.8
chr23_-_4933508 3.38 ENSDART00000137578
ENSDART00000141196
ngfa
nerve growth factor a (beta polypeptide)
chr24_-_18919562 3.30 ENSDART00000144244
ENSDART00000106188
ENSDART00000182518
cpa6
carboxypeptidase A6
chr25_-_3230187 3.26 ENSDART00000160545
cib1
calcium and integrin binding 1 (calmyrin)
chr6_+_7123980 3.26 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
si:ch211-237c6.4
chr20_-_2713120 3.26 ENSDART00000138753
ENSDART00000104606
rars2
arginyl-tRNA synthetase 2, mitochondrial (putative)
chr18_-_43866526 3.19 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr1_+_54626491 3.16 ENSDART00000136063
si:ch211-202h22.9
si:ch211-202h22.9
chr5_-_41841675 3.15 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr5_-_69621227 3.13 ENSDART00000178543
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr3_-_29506960 3.10 ENSDART00000141720
cyth4a
cytohesin 4a
chr3_-_57666996 3.10 ENSDART00000166855
timp2b
TIMP metallopeptidase inhibitor 2b
chr11_-_2478374 3.09 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr14_-_38872536 3.08 ENSDART00000184315
ENSDART00000127479
gsr
glutathione reductase
chr15_-_14193926 3.07 ENSDART00000162707
pnkp
polynucleotide kinase 3'-phosphatase
chr15_-_14194208 2.98 ENSDART00000188237
ENSDART00000183155
ENSDART00000165520
pnkp
polynucleotide kinase 3'-phosphatase
chr4_-_32458327 2.96 ENSDART00000182527
si:dkey-16p6.1
si:dkey-16p6.1
chr3_+_24618012 2.96 ENSDART00000111997
zgc:171506
zgc:171506
chr22_+_9764731 2.95 ENSDART00000161441
BX664625.4

chr11_-_1400507 2.95 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
rpl29
ribosomal protein L29
chr19_-_23249822 2.94 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr4_+_60430885 2.92 ENSDART00000184608
si:dkey-16p6.1
si:dkey-16p6.1
chr11_+_3254252 2.89 ENSDART00000123568
pmela
premelanosome protein a
chr19_+_19756425 2.82 ENSDART00000167606
hoxa3a
homeobox A3a
chr5_-_69620722 2.81 ENSDART00000097248
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr7_-_18508815 2.80 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr4_+_42419522 2.80 ENSDART00000135737
si:dkey-16p6.1
si:dkey-16p6.1
chr16_+_52343905 2.79 ENSDART00000131051
ifnlr1
interferon lambda receptor 1
chr7_+_30051880 2.65 ENSDART00000075609
pstpip1b
proline-serine-threonine phosphatase interacting protein 1b
chr16_-_16761164 2.65 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr14_-_46259523 2.63 ENSDART00000172890
si:ch211-113d11.8
si:ch211-113d11.8
chr8_+_23861461 2.61 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr14_+_26439227 2.59 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr3_-_31019715 2.59 ENSDART00000156687
ENSDART00000156127
ENSDART00000153945
si:dkeyp-71f10.5
si:dkeyp-71f10.5
chr15_-_41332865 2.59 ENSDART00000170014
si:dkey-121n8.7
si:dkey-121n8.7
chr15_-_41523225 2.57 ENSDART00000141202
ENSDART00000099290
ENSDART00000170395
ENSDART00000099437
si:dkey-230i18.2
si:dkey-121n8.7
nlrc9
si:dkey-230i18.2
si:dkey-121n8.7
NLR family CARD domain containing 9
chr25_+_4787431 2.55 ENSDART00000170640
myo5c
myosin VC
chr6_+_28051978 2.53 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr4_-_31984150 2.53 ENSDART00000162521
si:dkey-72l17.5
si:dkey-72l17.5
chr4_+_15944245 2.52 ENSDART00000134594
si:dkey-117n7.3
si:dkey-117n7.3
chr4_-_54381232 2.47 ENSDART00000157990
ENSDART00000169502
si:dkey-16p6.1
si:dkey-16p6.1
chr7_+_24881680 2.46 ENSDART00000058843
krcp
kelch repeat-containing protein
chr22_+_10676981 2.46 ENSDART00000138016
hyal2b
hyaluronoglucosaminidase 2b
chr17_+_12942634 2.45 ENSDART00000016597
nfkbiab
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr3_-_27065477 2.42 ENSDART00000185660
atf7ip2
activating transcription factor 7 interacting protein 2
chr3_-_23474416 2.40 ENSDART00000161672
si:dkey-225f5.5
si:dkey-225f5.5
chr23_+_43638982 2.40 ENSDART00000168646
slc10a7
solute carrier family 10, member 7
chr11_+_36675599 2.40 ENSDART00000170464
si:ch211-11c3.11
si:ch211-11c3.11
chr13_-_9598320 2.38 ENSDART00000184613
cpxm1a
carboxypeptidase X (M14 family), member 1a
chr7_-_18617187 2.35 ENSDART00000172419
si:ch211-119e14.1
si:ch211-119e14.1
chr8_+_18044257 2.33 ENSDART00000029255
glis1b
GLIS family zinc finger 1b
chr9_+_23003208 2.33 ENSDART00000021060
eaf2
ELL associated factor 2
chr6_+_6924637 2.32 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr23_+_36083529 2.32 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr19_+_7424347 2.31 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr18_+_40993369 2.31 ENSDART00000141162
si:dkey-283j8.1
si:dkey-283j8.1
chr24_+_5799764 2.31 ENSDART00000154482
si:ch211-157j23.2
si:ch211-157j23.2
chr22_+_5971404 2.28 ENSDART00000122153
BX322587.1

chr4_+_41835660 2.23 ENSDART00000171428
si:ch211-268b14.2
si:ch211-268b14.2
chr9_-_1959917 2.21 ENSDART00000082359
hoxd3a
homeobox D3a
chr5_+_32206378 2.16 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr21_-_40835069 2.15 ENSDART00000004686
limk1b
LIM domain kinase 1b
chr4_+_55059525 2.10 ENSDART00000128531
si:dkey-19c16.12
si:dkey-19c16.12
chr12_-_7157527 2.00 ENSDART00000152274
si:dkey-187i8.2
si:dkey-187i8.2
chr10_+_4987766 1.98 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr3_+_31058464 1.92 ENSDART00000153381
si:dkey-66i24.7
si:dkey-66i24.7
chr4_-_71210030 1.92 ENSDART00000186473
si:ch211-205a14.7
si:ch211-205a14.7
chr4_+_70913655 1.92 ENSDART00000180803
ENSDART00000185776
ENSDART00000193564
si:dkey-16p6.1
si:dkey-16p6.1
chr13_-_37649595 1.91 ENSDART00000115354
si:dkey-188i13.10
si:dkey-188i13.10
chr8_+_22277198 1.91 ENSDART00000005989
dffb
DNA fragmentation factor, beta polypeptide (caspase-activated DNase)
chr4_-_67980261 1.91 ENSDART00000182305
si:ch211-223k15.1
si:ch211-223k15.1
chr17_+_2727807 1.88 ENSDART00000178759
kcnk10b
potassium channel, subfamily K, member 10b
chr19_-_27550768 1.84 ENSDART00000142313
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr4_-_37693537 1.83 ENSDART00000167526
si:dkey-3p4.1
si:dkey-3p4.1
chr25_-_3892686 1.83 ENSDART00000043172
tmem258
transmembrane protein 258
chr5_-_24008997 1.83 ENSDART00000066645
eif1axa
eukaryotic translation initiation factor 1A, X-linked, a
chr6_-_39649504 1.81 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr1_+_230363 1.79 ENSDART00000153285
tfdp1b
transcription factor Dp-1, b
chr2_-_51644044 1.78 ENSDART00000157899
dad1
defender against cell death 1
chr20_-_54259780 1.77 ENSDART00000172631
fkbp3
FK506 binding protein 3
chr5_+_66132394 1.74 ENSDART00000073892
zgc:114041
zgc:114041
chr2_+_43749221 1.72 ENSDART00000142804
arhgap12a
Rho GTPase activating protein 12a
chr14_-_38873095 1.71 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
gsr
glutathione reductase
chr21_-_21641194 1.71 ENSDART00000010282
cbr1l
carbonyl reductase 1-like
chr10_-_31015535 1.70 ENSDART00000146116
panx3
pannexin 3
chr18_+_40993196 1.68 ENSDART00000115111
si:dkey-283j8.1
si:dkey-283j8.1
chr7_+_69653981 1.68 ENSDART00000090165
frem1a
Fras1 related extracellular matrix 1a
chr13_-_1349922 1.68 ENSDART00000140970
si:ch73-52p7.1
si:ch73-52p7.1
chr3_+_43102010 1.67 ENSDART00000162096
micall2a
mical-like 2a
chr20_+_14789305 1.65 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr4_-_71151245 1.64 ENSDART00000165415
si:dkey-193i10.4
si:dkey-193i10.4
chr13_+_45431660 1.63 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr7_+_4592867 1.62 ENSDART00000192614
si:dkey-83f18.15
si:dkey-83f18.15
chr11_+_3254524 1.61 ENSDART00000159459
pmela
premelanosome protein a
chr10_+_6907715 1.60 ENSDART00000041068
slc38a9
solute carrier family 38, member 9
chr17_-_10122204 1.59 ENSDART00000160751
BX088587.1

chr7_-_3639171 1.56 ENSDART00000064280
si:ch211-282j17.1
si:ch211-282j17.1
chr2_-_11504778 1.56 ENSDART00000186556
sdr16c5a
short chain dehydrogenase/reductase family 16C, member 5a
chr5_+_30520249 1.54 ENSDART00000013431
hmbsa
hydroxymethylbilane synthase a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc13b+hoxd13a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
2.9 8.6 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
2.4 7.2 GO:0005991 trehalose metabolic process(GO:0005991)
2.3 16.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.2 6.5 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
2.1 8.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.9 9.3 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
1.5 4.5 GO:0097435 fibril organization(GO:0097435)
0.8 3.8 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.6 6.9 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.6 4.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.6 4.1 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.5 3.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 4.9 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.4 4.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 3.5 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4 2.8 GO:0060017 parathyroid gland development(GO:0060017)
0.4 1.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.4 1.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 3.8 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3 1.0 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 2.0 GO:0070254 mucus secretion(GO:0070254)
0.3 1.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 4.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 4.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.3 3.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.3 1.9 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.3 1.3 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 1.5 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.2 5.9 GO:1990798 pancreas regeneration(GO:1990798)
0.2 0.7 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 1.7 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 0.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 1.2 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 3.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 1.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 4.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 2.9 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 0.8 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 7.2 GO:0030199 collagen fibril organization(GO:0030199)
0.2 3.8 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 4.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 14.2 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.2 1.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.0 GO:1902914 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 3.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 7.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 6.2 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.2 7.4 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.4 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.1 0.7 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 3.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 2.2 GO:0014823 response to activity(GO:0014823)
0.1 2.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 2.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 7.9 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 0.8 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 2.3 GO:0014812 muscle cell migration(GO:0014812)
0.1 0.7 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 2.1 GO:0008406 gonad development(GO:0008406)
0.1 4.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 7.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 4.0 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 0.8 GO:0044211 CTP salvage(GO:0044211)
0.1 0.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 1.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 8.6 GO:0001666 response to hypoxia(GO:0001666)
0.1 1.5 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 1.0 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.1 8.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 9.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 4.5 GO:0042493 response to drug(GO:0042493)
0.1 0.7 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.9 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 6.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 8.5 GO:0001503 ossification(GO:0001503)
0.1 1.5 GO:0042476 odontogenesis(GO:0042476)
0.1 1.3 GO:0006301 postreplication repair(GO:0006301)
0.1 2.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 5.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 8.7 GO:0051216 cartilage development(GO:0051216)
0.1 2.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 1.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 5.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 3.0 GO:0051028 mRNA transport(GO:0051028)
0.0 1.3 GO:0019915 lipid storage(GO:0019915)
0.0 1.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.7 GO:0033334 fin morphogenesis(GO:0033334)
0.0 2.8 GO:0048884 neuromast development(GO:0048884)
0.0 1.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 1.0 GO:0016441 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 1.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 2.7 GO:0006413 translational initiation(GO:0006413)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 5.3 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 7.3 GO:0001525 angiogenesis(GO:0001525)
0.0 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0045761 cAMP biosynthetic process(GO:0006171) regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 3.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 2.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.2 GO:0001570 vasculogenesis(GO:0001570)
0.0 5.4 GO:0006412 translation(GO:0006412)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 2.0 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 3.0 GO:0030041 actin filament polymerization(GO:0030041)
0.0 1.1 GO:0006518 peptide metabolic process(GO:0006518)
0.0 1.1 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.7 6.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.5 1.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 12.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 4.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 5.8 GO:0000813 ESCRT I complex(GO:0000813)
0.3 2.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.3 2.4 GO:0000974 Prp19 complex(GO:0000974)
0.3 3.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 11.0 GO:0005861 troponin complex(GO:0005861)
0.2 4.1 GO:0042555 MCM complex(GO:0042555)
0.2 1.5 GO:0030914 STAGA complex(GO:0030914)
0.2 26.5 GO:0016459 myosin complex(GO:0016459)
0.2 7.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 0.7 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 15.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 8.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 4.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 2.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 3.1 GO:0043186 P granule(GO:0043186)
0.1 6.2 GO:0005604 basement membrane(GO:0005604)
0.1 3.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 6.6 GO:0030018 Z disc(GO:0030018)
0.1 1.7 GO:0005921 gap junction(GO:0005921)
0.0 12.7 GO:0000323 lytic vacuole(GO:0000323)
0.0 11.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 15.3 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.2 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 2.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.3 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
2.4 7.2 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
2.1 8.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
2.0 6.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
1.4 8.1 GO:0004743 pyruvate kinase activity(GO:0004743)
1.2 8.1 GO:0004974 leukotriene receptor activity(GO:0004974)
1.0 7.9 GO:0003993 acid phosphatase activity(GO:0003993)
1.0 6.9 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9 4.4 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.8 4.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.8 3.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.7 12.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.7 3.5 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.6 5.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 3.0 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.5 6.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.5 6.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 4.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 1.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 2.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 5.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 4.0 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.3 0.9 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.3 4.6 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.3 3.4 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.3 1.5 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 2.9 GO:0005158 insulin receptor binding(GO:0005158)
0.2 3.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 3.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 5.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.6 GO:0000035 acyl binding(GO:0000035)
0.2 4.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 10.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.7 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 4.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 9.6 GO:0017124 SH3 domain binding(GO:0017124)
0.2 8.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 6.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 3.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.6 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 3.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.7 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 18.2 GO:0003774 motor activity(GO:0003774)
0.1 1.5 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 16.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 7.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.7 GO:0022829 wide pore channel activity(GO:0022829)
0.1 1.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 4.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 7.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 9.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 5.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 7.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 2.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 10.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 2.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 3.8 GO:0042277 peptide binding(GO:0042277)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 22.5 GO:0038023 signaling receptor activity(GO:0038023)
0.0 2.8 GO:0015293 symporter activity(GO:0015293)
0.0 3.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 1.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 3.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.0 GO:0004386 helicase activity(GO:0004386)
0.0 2.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.0 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2 4.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 8.1 PID ENDOTHELIN PATHWAY Endothelins
0.1 16.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 4.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 1.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 4.2 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.8 8.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.4 11.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 1.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 13.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 4.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 4.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 8.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 6.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 0.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.8 REACTOME TRANSLATION Genes involved in Translation
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination