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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxc6a+hoxc6b

Z-value: 0.54

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Transcription factors associated with hoxc6a+hoxc6b

Gene Symbol Gene ID Gene Info
hoxc6a
ENSDARG00000070343 homeobox C6a
hoxc6b
ENSDARG00000101954 homeobox C6b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc6bdr11_v1_chr11_+_2198831_2198831-0.381.5e-04Click!
hoxc6adr11_v1_chr23_+_36115541_36115541-0.302.9e-03Click!

Activity profile of hoxc6a+hoxc6b motif

Sorted Z-values of hoxc6a+hoxc6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_46779934 9.30 ENSDART00000085136
clcn2c
chloride channel 2c
chr8_-_36287046 4.67 ENSDART00000162877
si:busm1-194e12.11
si:busm1-194e12.11
chr18_+_13162728 4.64 ENSDART00000101472
tat
tyrosine aminotransferase
chr22_-_24791505 3.83 ENSDART00000136837
vtg4
vitellogenin 4
chr20_-_5291012 3.76 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr21_+_25236297 3.72 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr16_-_44945224 3.58 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr5_-_37103487 3.48 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr24_-_38110779 3.42 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr22_+_19552987 3.36 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr25_-_21031007 2.99 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr11_+_37250839 2.94 ENSDART00000170209
il17rc
interleukin 17 receptor C
chr8_+_52637507 2.74 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr21_-_44081540 2.62 ENSDART00000130833
FO704810.1

chr2_-_31833347 2.41 ENSDART00000109460
nol7
nucleolar protein 7
chr22_-_16154771 2.38 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr19_-_5769728 2.32 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr21_-_26490186 2.08 ENSDART00000009889
zgc:110540
zgc:110540
chr5_+_56023186 2.03 ENSDART00000156230
fzd9a
frizzled class receptor 9a
chr19_-_5769553 2.01 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr5_-_50992690 1.93 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr3_-_31254379 1.84 ENSDART00000189376
apnl
actinoporin-like protein
chr6_-_43283122 1.77 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr24_+_21514283 1.66 ENSDART00000007066
cdk8
cyclin-dependent kinase 8
chr15_-_17618800 1.64 ENSDART00000157185
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr12_-_4532066 1.62 ENSDART00000092687
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr16_-_42965192 1.59 ENSDART00000113714
mtx1a
metaxin 1a
chr24_+_12989727 1.55 ENSDART00000126842
ENSDART00000129309
flj11011l
hypothetical protein FLJ11011-like (H. sapiens)
chr4_+_57881965 1.54 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr2_-_17392799 1.50 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr3_-_19368435 1.50 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr2_-_59327299 1.47 ENSDART00000133734
ftr36
finTRIM family, member 36
chr21_+_45841731 1.46 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr19_+_1688727 1.40 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr8_-_39884359 1.35 ENSDART00000131372
mlec
malectin
chr2_+_15048410 1.34 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr13_-_52089003 1.34 ENSDART00000187600
tmem254
transmembrane protein 254
chr16_+_54209504 1.33 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr6_-_16717878 1.32 ENSDART00000153552
nomo
nodal modulator
chr13_+_646700 1.31 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr13_+_35339182 1.31 ENSDART00000019323
jag1b
jagged 1b
chr22_-_5252005 1.25 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr10_+_29850330 1.22 ENSDART00000168898
hspa8
heat shock protein 8
chr4_+_12966640 1.20 ENSDART00000113357
vhll
von Hippel-Lindau tumor suppressor like
chr16_+_29509133 1.18 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr11_+_1602916 1.18 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr1_+_32051581 1.15 ENSDART00000146602
sts
steroid sulfatase (microsomal), isozyme S
chr2_-_37140423 1.13 ENSDART00000144220
tspan37
tetraspanin 37
chr22_-_10121880 1.11 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr3_+_7808459 1.11 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr15_+_34592215 1.10 ENSDART00000099776
tspan13a
tetraspanin 13a
chr3_+_26342768 1.09 ENSDART00000163832
si:ch211-156b7.4
si:ch211-156b7.4
chr20_+_25586099 1.06 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr11_+_11974708 1.05 ENSDART00000125060
zgc:64002
zgc:64002
chr20_+_54309148 1.01 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr18_-_48983690 1.00 ENSDART00000182359
FO681288.3

chr2_-_17393216 1.00 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr3_-_31158382 0.98 ENSDART00000076764
ENSDART00000076796
smg1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr22_-_36530902 0.97 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr2_+_2169337 0.96 ENSDART00000179939
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr20_+_54299419 0.94 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr5_-_42904329 0.94 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr9_+_41080029 0.92 ENSDART00000141179
ENSDART00000019289
zgc:136439
zgc:136439
chr23_-_20051369 0.91 ENSDART00000049836
bgnb
biglycan b
chr14_-_48765262 0.90 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr20_+_54304800 0.88 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr7_-_8712148 0.88 ENSDART00000065488
tex261
testis expressed 261
chr24_+_19415124 0.87 ENSDART00000186931
sulf1
sulfatase 1
chr25_+_29474982 0.87 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr8_+_29635968 0.86 ENSDART00000139029
ENSDART00000091409
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr7_-_5375214 0.85 ENSDART00000033316
vangl2
VANGL planar cell polarity protein 2
chr5_+_41477954 0.84 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr17_-_16422654 0.84 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr22_+_508290 0.83 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr5_+_66433287 0.83 ENSDART00000170757
kntc1
kinetochore associated 1
chr14_+_4807207 0.82 ENSDART00000167145
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr6_+_35362225 0.80 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr5_+_41477526 0.78 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr19_+_10592778 0.77 ENSDART00000135488
ENSDART00000151624
si:dkey-211g8.5
si:dkey-211g8.5
chr7_+_19495905 0.76 ENSDART00000125584
ENSDART00000173774
si:ch211-212k18.8
si:ch211-212k18.8
chr4_-_5108844 0.74 ENSDART00000132666
ENSDART00000136096
tmem209
transmembrane protein 209
chr20_-_45812144 0.73 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr10_-_34916208 0.73 ENSDART00000187371
ccna1
cyclin A1
chr4_-_49582758 0.66 ENSDART00000180834
ENSDART00000187608
si:dkey-159n16.2
si:dkey-159n16.2
chr1_+_47499888 0.66 ENSDART00000027624
stn1
STN1, CST complex subunit
chr10_-_7386475 0.65 ENSDART00000167963
nrg1
neuregulin 1
chr18_+_13275735 0.65 ENSDART00000148127
plcg2
phospholipase C, gamma 2
chr14_-_46173265 0.65 ENSDART00000164321
zmp:0000000758
zmp:0000000758
chr13_+_33268657 0.64 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr10_+_11767791 0.63 ENSDART00000092047
ppwd1
peptidylprolyl isomerase domain and WD repeat containing 1
chr10_+_22527715 0.61 ENSDART00000134864
gigyf1b
GRB10 interacting GYF protein 1b
chr10_-_43771447 0.61 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr7_-_34448076 0.61 ENSDART00000170935
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr21_-_38853737 0.60 ENSDART00000184100
tlr22
toll-like receptor 22
chr25_+_22320738 0.58 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr14_+_21722235 0.57 ENSDART00000183667
stx3a
syntaxin 3A
chr7_+_4657987 0.56 ENSDART00000144321
ENSDART00000142344
si:dkey-83f18.2
si:dkey-83f18.2
chr22_-_20166660 0.56 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr9_-_32177117 0.56 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr9_-_30576522 0.56 ENSDART00000101085
morc3a
MORC family CW-type zinc finger 3a
chr21_+_43172506 0.55 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr24_+_13316737 0.55 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr19_+_43359075 0.54 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr4_-_46915962 0.54 ENSDART00000169555
si:ch211-134c10.1
si:ch211-134c10.1
chr1_-_51038885 0.53 ENSDART00000035150
spast
spastin
chr1_-_9195629 0.51 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr2_+_10878406 0.51 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr8_+_17775247 0.51 ENSDART00000112356
si:ch211-150o23.3
si:ch211-150o23.3
chr1_-_669717 0.50 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr24_+_28953089 0.50 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr9_-_42418470 0.48 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr6_+_25257728 0.48 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr6_+_12527725 0.47 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr4_-_75158035 0.45 ENSDART00000174353
CABZ01066312.1

chr24_-_40860603 0.45 ENSDART00000188032
CU633479.7

chr3_+_1637358 0.45 ENSDART00000180266
CR394546.5

chr23_-_36418708 0.42 ENSDART00000132273
znf740b
zinc finger protein 740b
chr10_-_11261565 0.42 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr5_+_32076109 0.42 ENSDART00000051357
ENSDART00000144510
zmat5
zinc finger, matrin-type 5
chr7_-_50410524 0.42 ENSDART00000083346
hypk
huntingtin interacting protein K
chr21_-_32301109 0.41 ENSDART00000139890
clk4b
CDC-like kinase 4b
chr20_+_25225112 0.41 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr5_+_65871688 0.41 ENSDART00000175217
FAM163B (1 of many)
family with sequence similarity 163 member B
chr7_-_66868543 0.40 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr5_+_61459422 0.40 ENSDART00000050902
polr2j
polymerase (RNA) II (DNA directed) polypeptide J
chr20_-_13660767 0.40 ENSDART00000127654
TAGAP
si:ch211-122h15.4
chr15_+_29140126 0.39 ENSDART00000060034
zgc:113149
zgc:113149
chr2_-_10877765 0.39 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr8_-_19246342 0.39 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
chr11_-_10456387 0.38 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr21_-_26028205 0.38 ENSDART00000034875
sdf2
stromal cell-derived factor 2
chr14_-_16082806 0.37 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr10_+_11261576 0.36 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr16_-_7793457 0.35 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr20_-_13660600 0.35 ENSDART00000063826
TAGAP
si:ch211-122h15.4
chr2_+_11923615 0.34 ENSDART00000126118
trove2
TROVE domain family, member 2
chr11_-_36156935 0.34 ENSDART00000124935
ENSDART00000138609
brk1
gpx1a
BRICK1, SCAR/WAVE actin-nucleating complex subunit
glutathione peroxidase 1a
chr15_-_2754056 0.33 ENSDART00000129380
ppp5c
protein phosphatase 5, catalytic subunit
chr1_+_27977297 0.33 ENSDART00000180692
ENSDART00000166819
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr8_+_36560019 0.32 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr10_-_26512993 0.31 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
si:dkey-5g14.1
chr11_-_10456553 0.30 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr19_+_43297546 0.28 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr15_-_43284021 0.27 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr16_+_40024883 0.27 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr7_+_66884570 0.26 ENSDART00000082664
sbf2
SET binding factor 2
chr25_-_27722614 0.26 ENSDART00000190154
zgc:153935
zgc:153935
chr7_+_19495379 0.26 ENSDART00000180514
si:ch211-212k18.8
si:ch211-212k18.8
chr15_+_857148 0.25 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr6_+_24398907 0.22 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr5_+_29851433 0.22 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr17_+_51682429 0.20 ENSDART00000004379
nol10
nucleolar protein 10
chr10_+_43039947 0.19 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr3_+_46635527 0.18 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr15_-_26931541 0.17 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr5_+_33498253 0.16 ENSDART00000140993
ms4a17c.2
membrane-spanning 4-domains, subfamily A, member 17c.2
chr4_+_2482046 0.16 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr1_+_57787642 0.16 ENSDART00000127091
si:dkey-1c7.2
si:dkey-1c7.2
chr11_+_11267493 0.16 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr20_+_38032143 0.16 ENSDART00000032161
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr22_+_2751887 0.15 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr20_-_34750045 0.14 ENSDART00000186130
znf395b
zinc finger protein 395b
chr8_-_30204650 0.13 ENSDART00000133209
zgc:162939
zgc:162939
chr10_-_26512742 0.12 ENSDART00000135951
si:dkey-5g14.1
si:dkey-5g14.1
chr4_+_59845617 0.12 ENSDART00000167626
ENSDART00000123157
si:dkey-196n19.2
si:dkey-196n19.2
chr6_+_7533601 0.11 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr7_-_67248829 0.10 ENSDART00000192442
znf143a
zinc finger protein 143a
chr5_-_51198430 0.10 ENSDART00000132503
ENSDART00000097473
ENSDART00000165870
snapc4
small nuclear RNA activating complex, polypeptide 4
chr23_-_35790235 0.10 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr7_+_7696665 0.10 ENSDART00000091099
ino80b
INO80 complex subunit B
chr7_+_24573721 0.09 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr20_-_34750363 0.08 ENSDART00000152845
znf395b
zinc finger protein 395b
chr3_+_28939759 0.07 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr13_+_9468535 0.07 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
HTRA2 (1 of many)
si:dkey-265c15.6
chr7_+_4694924 0.07 ENSDART00000144873
si:ch211-225k7.3
si:ch211-225k7.3
chr13_-_50366950 0.07 ENSDART00000098209
sirt1
sirtuin 1
chr18_+_35128685 0.06 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr19_+_7847920 0.04 ENSDART00000132454
si:dkeyp-85e10.1
si:dkeyp-85e10.1
chr7_-_46777876 0.04 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr3_+_23092762 0.04 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr1_+_58242498 0.04 ENSDART00000149091
ggt1l2.2
gamma-glutamyltransferase 1 like 2.2
chr7_+_66884291 0.03 ENSDART00000187499
sbf2
SET binding factor 2
chr24_+_9693951 0.03 ENSDART00000082411
topbp1
DNA topoisomerase II binding protein 1
chr4_-_11064073 0.03 ENSDART00000150760
si:dkey-21h14.8
si:dkey-21h14.8
chr21_-_5856050 0.02 ENSDART00000115367
CABZ01071020.1

chr19_+_43885770 0.02 ENSDART00000135599
lypla2
lysophospholipase II
chr13_+_15656042 0.02 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr6_+_49551614 0.02 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr1_+_22851261 0.02 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr23_+_45339684 0.02 ENSDART00000149410
ENSDART00000102441
psip1b
PC4 and SFRS1 interacting protein 1b
chr14_-_413273 0.01 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc6a+hoxc6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.6 GO:0002369 T cell cytokine production(GO:0002369)
0.5 2.6 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.4 2.2 GO:0000012 single strand break repair(GO:0000012)
0.3 3.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 9.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.3 1.8 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.2 0.6 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.2 0.8 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.2 1.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 0.6 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.2 1.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.2 0.5 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 0.9 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 1.0 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.4 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 1.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 3.9 GO:0032355 response to estradiol(GO:0032355)
0.1 1.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.8 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 1.3 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 1.8 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.9 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1 0.7 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.1 1.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.0 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.7 GO:0016233 telomere capping(GO:0016233)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.7 GO:0050821 protein stabilization(GO:0050821)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 1.5 GO:0051607 defense response to virus(GO:0051607)
0.0 1.1 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 3.4 GO:0050808 synapse organization(GO:0050808)
0.0 0.6 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 3.7 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 0.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 1.2 GO:0030891 VCB complex(GO:0030891)
0.2 1.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 8.0 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 3.8 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.5 3.8 GO:0045735 nutrient reservoir activity(GO:0045735)
0.5 9.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 2.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.3 3.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 2.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.3 0.8 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 0.9 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 3.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 0.6 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.5 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 4.5 GO:0008483 transaminase activity(GO:0008483)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 1.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 3.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 2.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.4 GO:0002039 p53 binding(GO:0002039)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.3 GO:0005112 Notch binding(GO:0005112)
0.1 1.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.9 GO:0050661 NADP binding(GO:0050661)
0.0 3.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 2.9 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 1.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 4.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase