Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for hoxd3a

Z-value: 0.36

Motif logo

logo of

Transcription factors associated with hoxd3a

Gene Symbol Gene ID Gene Info
hoxd3a
ENSDARG00000059280 homeobox D3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd3adr11_v1_chr9_-_1949915_19499150.205.1e-02Click!

Activity profile of hoxd3a motif

Sorted Z-values of hoxd3a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_29160102 4.88 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr25_+_31276842 4.37 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr1_+_52392511 1.97 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr8_-_31107537 1.84 ENSDART00000098925
vgll4l
vestigial like 4 like
chr19_+_2631565 1.77 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr18_+_3037998 1.75 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr12_+_22580579 1.48 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr4_+_73085993 1.47 ENSDART00000165749
si:ch73-170d6.2
si:ch73-170d6.2
chr21_-_35419486 1.46 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr9_-_21918963 1.45 ENSDART00000090782
lmo7a
LIM domain 7a
chr17_+_16046314 1.44 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr19_-_7690975 1.42 ENSDART00000151384
si:dkey-204a24.10
si:dkey-204a24.10
chr22_+_16308450 1.31 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr4_+_58576146 1.21 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr5_+_30384554 1.16 ENSDART00000135483
zgc:158412
zgc:158412
chr20_-_7072487 1.08 ENSDART00000145954
si:ch211-121a2.2
si:ch211-121a2.2
chr7_-_48667056 1.08 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr13_-_35808904 1.02 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr19_+_41464870 1.00 ENSDART00000102778
dlx6a
distal-less homeobox 6a
chr3_+_27798094 0.91 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr11_+_2391649 0.80 ENSDART00000104571
igfbp6a
insulin-like growth factor binding protein 6a
chr19_-_6988837 0.79 ENSDART00000145741
ENSDART00000167640
znf384l
zinc finger protein 384 like
chr19_+_11217279 0.78 ENSDART00000181859
si:ch73-109i22.2
si:ch73-109i22.2
chr16_+_5251768 0.77 ENSDART00000144558
plecb
plectin b
chr6_+_19948043 0.74 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr15_+_31899312 0.72 ENSDART00000155315
frya
furry homolog a (Drosophila)
chr19_-_10971230 0.71 ENSDART00000166196
LO018584.1

chr6_-_40029423 0.68 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr3_-_34084387 0.67 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr20_-_14925281 0.65 ENSDART00000152641
dnm3a
dynamin 3a
chr11_+_2391469 0.64 ENSDART00000182121
igfbp6a
insulin-like growth factor binding protein 6a
chr6_+_41191482 0.63 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr5_+_28160503 0.62 ENSDART00000051516
tacr1a
tachykinin receptor 1a
chr15_+_41027466 0.59 ENSDART00000075940
mtnr1ba
melatonin receptor type 1Ba
chr20_+_35484070 0.58 ENSDART00000026234
ENSDART00000141675
mep1a.2
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr10_+_39091353 0.56 ENSDART00000125986
si:ch73-1a9.4
si:ch73-1a9.4
chr1_+_56755536 0.47 ENSDART00000157727
CABZ01049361.1

chr22_-_10117918 0.46 ENSDART00000177475
ENSDART00000128590
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr10_+_39091716 0.44 ENSDART00000193072
si:ch73-1a9.4
si:ch73-1a9.4
chr14_+_30762131 0.42 ENSDART00000145039
si:ch211-145o7.3
si:ch211-145o7.3
chr14_+_5385855 0.41 ENSDART00000031508
lbx2
ladybird homeobox 2
chr15_-_35252522 0.39 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr4_-_71210030 0.39 ENSDART00000186473
si:ch211-205a14.7
si:ch211-205a14.7
chr8_+_25034544 0.39 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr10_+_39084354 0.37 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr7_-_46777876 0.35 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr7_+_24165371 0.33 ENSDART00000173472
si:ch211-216p19.5
si:ch211-216p19.5
chr9_+_22364997 0.32 ENSDART00000188054
ENSDART00000046116
crygs3
crystallin, gamma S3
chr20_-_37813863 0.30 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr20_-_14924858 0.26 ENSDART00000047039
dnm3a
dynamin 3a
chr17_-_29311835 0.25 ENSDART00000104224
tecpr2
tectonin beta-propeller repeat containing 2
chr23_+_579893 0.25 ENSDART00000189098
BX323461.1

chr16_+_31804590 0.25 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr20_+_539852 0.21 ENSDART00000185994
dse
dermatan sulfate epimerase
chr8_+_22405477 0.15 ENSDART00000148267
si:dkey-23c22.7
si:dkey-23c22.7
chr14_+_22591624 0.15 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr14_-_2933185 0.14 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr10_-_5847655 0.13 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr6_+_3280939 0.13 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr7_-_7797654 0.12 ENSDART00000084503
ENSDART00000192779
ENSDART00000173079
trmt10b
tRNA methyltransferase 10B
chr22_-_209741 0.12 ENSDART00000171954
ora1
olfactory receptor class A related 1
chr8_+_17078692 0.11 ENSDART00000023206
plk2b
polo-like kinase 2b (Drosophila)
chr7_-_12464412 0.10 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr13_-_7233811 0.09 ENSDART00000162026
ninl
ninein-like
chr10_-_41400049 0.09 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr15_-_38361787 0.09 ENSDART00000155758
trpc2a
transient receptor potential cation channel, subfamily C, member 2a
chr10_-_40484531 0.08 ENSDART00000142464
ENSDART00000180318
taar20z
trace amine associated receptor 20z
chr20_-_9095105 0.08 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr18_+_9362455 0.07 ENSDART00000187025
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr6_+_32382743 0.07 ENSDART00000190009
dock7
dedicator of cytokinesis 7
chr16_+_45425181 0.07 ENSDART00000168591
phf1
PHD finger protein 1
chr13_-_39736938 0.07 ENSDART00000141645
zgc:171482
zgc:171482
chr16_+_45424907 0.07 ENSDART00000134471
phf1
PHD finger protein 1
chr1_-_40911332 0.06 ENSDART00000027463
hmx4
H6 family homeobox 4
chr12_+_30265802 0.05 ENSDART00000182412
afap1l2
actin filament associated protein 1-like 2
chr11_+_33818179 0.04 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr5_-_28109416 0.04 ENSDART00000042002
si:ch211-48m9.1
si:ch211-48m9.1
chr8_+_41037541 0.04 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr11_-_25777318 0.04 ENSDART00000079328
plch2b
phospholipase C, eta 2b
chr2_+_54327160 0.03 ENSDART00000182320
LO018508.1

chr23_-_44470253 0.02 ENSDART00000176333
si:ch1073-228j22.2
si:ch1073-228j22.2
chr3_+_30500968 0.02 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd3a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.2 1.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 1.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 4.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 0.4 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.5 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 4.9 GO:0006096 glycolytic process(GO:0006096)
0.0 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 1.5 GO:0051014 actin filament severing(GO:0051014)
0.0 1.0 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 1.3 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 1.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.0 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.1 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 1.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:1990845 adaptive thermogenesis(GO:1990845)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.7 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0001726 ruffle(GO:0001726)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.6 GO:0016496 substance P receptor activity(GO:0016496)
0.1 1.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.4 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex