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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for ikzf1

Z-value: 1.32

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Transcription factors associated with ikzf1

Gene Symbol Gene ID Gene Info
ikzf1
ENSDARG00000013539 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ikzf1dr11_v1_chr13_-_15986871_159868710.196.6e-02Click!

Activity profile of ikzf1 motif

Sorted Z-values of ikzf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_32817274 22.05 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr5_-_71722257 19.11 ENSDART00000013404
ak1
adenylate kinase 1
chr5_+_32222303 17.73 ENSDART00000051362
myhc4
myosin heavy chain 4
chr25_+_29161609 17.19 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr6_-_29195642 13.91 ENSDART00000078625
dpt
dermatopontin
chr23_-_23256726 13.65 ENSDART00000131353
si:dkey-98j1.5
si:dkey-98j1.5
chr6_-_39764995 12.44 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr7_+_39386982 12.36 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr8_-_18535822 10.53 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr22_-_29191152 10.42 ENSDART00000132702
pvalb7
parvalbumin 7
chr22_-_237651 9.89 ENSDART00000075210
zgc:66156
zgc:66156
chr25_-_31396479 9.47 ENSDART00000156828
prr33
proline rich 33
chr22_-_282498 8.96 ENSDART00000182766
CABZ01079178.1

chr2_-_15324837 8.23 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr23_+_6077503 7.38 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr2_+_25278107 7.29 ENSDART00000131977
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr13_-_2189761 7.23 ENSDART00000166255
mlip
muscular LMNA-interacting protein
chr3_-_52614747 6.89 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr9_-_21067971 6.87 ENSDART00000004333
tbx15
T-box 15
chr19_-_38539670 6.75 ENSDART00000136775
col16a1
collagen, type XVI, alpha 1
chr2_-_21335131 6.67 ENSDART00000057022
klhl40a
kelch-like family member 40a
chr24_+_35947077 6.27 ENSDART00000173406
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr17_+_2549503 5.86 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr15_-_2640966 5.66 ENSDART00000063320
cldne
claudin e
chr1_+_1838164 5.57 ENSDART00000006013
atp1a1a.5
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5
chr1_-_59116617 5.55 ENSDART00000137471
ENSDART00000140490
MFAP4 (1 of many)
si:zfos-2330d3.7
chr7_+_31879649 5.48 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr13_+_24842857 5.46 ENSDART00000123866
dusp13a
dual specificity phosphatase 13a
chr8_+_1009831 5.36 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr20_+_15982482 5.32 ENSDART00000020999
angptl1a
angiopoietin-like 1a
chr23_+_36083529 5.27 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr21_-_131236 5.06 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr5_-_57641257 5.01 ENSDART00000149282
hspb2
heat shock protein, alpha-crystallin-related, b2
chr20_+_27194833 5.00 ENSDART00000150072
si:dkey-85n7.8
si:dkey-85n7.8
chr1_-_10914523 4.91 ENSDART00000007013
dmd
dystrophin
chr12_-_26430507 4.78 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr7_-_35432901 4.69 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr18_+_20494413 4.67 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr11_+_10541258 4.61 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr11_-_21030070 4.51 ENSDART00000186322
fmoda
fibromodulin a
chr13_-_13754091 4.34 ENSDART00000131255
ky
kyphoscoliosis peptidase
chr17_+_23462972 4.31 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr7_-_2039060 4.22 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr17_-_14671098 4.20 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr6_+_18142623 4.17 ENSDART00000169431
ENSDART00000158841
si:dkey-237i9.8
si:dkey-237i9.8
chr3_+_30921246 4.15 ENSDART00000076850
cldni
claudin i
chr6_-_30485009 4.11 ENSDART00000025698
zgc:153311
zgc:153311
chr12_-_26415499 4.09 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr18_-_41375120 4.05 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr9_-_21067673 3.98 ENSDART00000180257
tbx15
T-box 15
chr5_+_37517800 3.87 ENSDART00000048107
FP102018.1
Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA.
chr19_-_9648542 3.84 ENSDART00000172628
clcn1a
chloride channel, voltage-sensitive 1a
chr4_-_4119396 3.77 ENSDART00000067409
ENSDART00000138221
lmod2b
leiomodin 2 (cardiac) b
chr21_-_35534401 3.76 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr5_-_41831646 3.71 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr6_-_40899618 3.63 ENSDART00000153949
ENSDART00000021969
zgc:172271
zgc:172271
chr2_+_35993404 3.60 ENSDART00000170845
lamc2
laminin, gamma 2
chr12_-_47782623 3.59 ENSDART00000115742
selenou1b
selenoprotein U1b
chr15_+_42573909 3.50 ENSDART00000181801
CLDN8 (1 of many)
zgc:110333
chr3_+_49021079 3.45 ENSDART00000162012
zgc:163083
zgc:163083
chr17_-_45370200 3.40 ENSDART00000186208
znf106a
zinc finger protein 106a
chr1_+_51496862 3.39 ENSDART00000150433
meis1a
Meis homeobox 1 a
chr3_-_59981162 3.35 ENSDART00000128790
cdr2l
cerebellar degeneration-related protein 2-like
chr21_-_40835069 3.30 ENSDART00000004686
limk1b
LIM domain kinase 1b
chr5_-_31712399 3.28 ENSDART00000141328
pip5kl1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr20_+_54738210 3.23 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr2_+_55665322 3.18 ENSDART00000183636
ENSDART00000183814
klf2b
Kruppel-like factor 2b
chr17_-_14876758 3.16 ENSDART00000155857
nid2a
nidogen 2a (osteonidogen)
chr17_+_45607580 3.14 ENSDART00000122583
si:ch211-202f3.4
si:ch211-202f3.4
chr12_+_20641102 3.14 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr19_+_22216778 3.05 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr17_+_996509 3.00 ENSDART00000158830
cyp1c2
cytochrome P450, family 1, subfamily C, polypeptide 2
chr16_+_20915319 3.00 ENSDART00000079383
hoxa9b
homeobox A9b
chr5_-_28606916 3.00 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr24_-_38816725 2.97 ENSDART00000063231
nog2
noggin 2
chr2_-_689047 2.93 ENSDART00000122732
foxc1a
forkhead box C1a
chr15_-_23376541 2.92 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr3_-_33967767 2.84 ENSDART00000151493
ENSDART00000151160
ighv1-4
immunoglobulin heavy variable 1-4
chr12_+_17042754 2.83 ENSDART00000066439
ch25h
cholesterol 25-hydroxylase
chr4_-_12914163 2.81 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr21_+_13383413 2.78 ENSDART00000151345
zgc:113162
zgc:113162
chr15_-_2652640 2.75 ENSDART00000146094
cldnf
claudin f
chr7_+_39410180 2.73 ENSDART00000168641
CT030188.1

chr8_+_44475793 2.72 ENSDART00000190118
si:ch73-211l2.3
si:ch73-211l2.3
chr8_-_52229462 2.71 ENSDART00000185949
ENSDART00000051825
tcf7l1b
transcription factor 7 like 1b
chr3_-_59981476 2.69 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr7_+_17816470 2.67 ENSDART00000173807
eml3
echinoderm microtubule associated protein like 3
chr9_-_34260214 2.67 ENSDART00000012385
me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr21_+_19525141 2.66 ENSDART00000058489
gzma
granzyme A
chr5_+_54938634 2.61 ENSDART00000163050
ENSDART00000145765
cd180
CD180 molecule
chr8_+_52642869 2.59 ENSDART00000163617
ENSDART00000189997
si:dkey-90l8.3
si:dkey-90l8.3
chr22_+_15898221 2.58 ENSDART00000062587
klf2a
Kruppel-like factor 2a
chr5_-_26181863 2.55 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr5_-_41841892 2.55 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6
chr1_-_59104145 2.53 ENSDART00000132495
ENSDART00000152457
MFAP4 (1 of many)
si:zfos-2330d3.7
si:zfos-2330d3.1
si:zfos-2330d3.7
chr25_-_23526058 2.50 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr18_-_21177674 2.49 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr2_+_55665095 2.49 ENSDART00000059188
klf2b
Kruppel-like factor 2b
chr17_-_33416020 2.48 ENSDART00000140149
ccdc28a
coiled-coil domain containing 28A
chr7_+_17816006 2.47 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr19_+_24872159 2.46 ENSDART00000158490
si:ch211-195b13.1
si:ch211-195b13.1
chr7_-_58098814 2.45 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr15_-_34458495 2.44 ENSDART00000059954
meox2a
mesenchyme homeobox 2a
chr12_-_8070969 2.43 ENSDART00000020995
tmem26b
transmembrane protein 26b
chr5_-_41841675 2.39 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr5_+_30741730 2.39 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
ftr83
finTRIM family, member 83
chr15_-_33933790 2.38 ENSDART00000165162
ENSDART00000182258
ENSDART00000183240
mag
myelin associated glycoprotein
chr10_-_8358396 2.37 ENSDART00000059322
csgalnact1a
chondroitin sulfate N-acetylgalactosaminyltransferase 1a
chr17_+_10242166 2.33 ENSDART00000170420
clec14a
C-type lectin domain containing 14A
chr3_-_58644920 2.33 ENSDART00000155953
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr5_-_41838354 2.32 ENSDART00000146793
si:dkey-65b12.6
si:dkey-65b12.6
chr3_+_32443395 2.32 ENSDART00000188447
prr12b
proline rich 12b
chr23_+_34047413 2.32 ENSDART00000143933
ENSDART00000123925
ENSDART00000176139
chchd6a
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr18_-_16792561 2.32 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr7_-_24390879 2.30 ENSDART00000036680
ptgr1
prostaglandin reductase 1
chr18_+_20869923 2.26 ENSDART00000138471
pgpep1l
pyroglutamyl-peptidase I-like
chr1_-_206208 2.24 ENSDART00000060968
adprhl1
ADP-ribosylhydrolase like 1
chr10_+_31951338 2.23 ENSDART00000019416
lhfpl6
LHFPL tetraspan subfamily member 6
chr1_-_26702930 2.21 ENSDART00000109297
ENSDART00000152389
foxe1
forkhead box E1
chr7_+_12950507 2.21 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr7_+_39410393 2.16 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr24_-_25184553 2.15 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr21_-_25741096 2.14 ENSDART00000181756
cldnh
claudin h
chr22_+_30543437 2.14 ENSDART00000137983
si:dkey-103k4.1
si:dkey-103k4.1
chr17_+_25414033 2.11 ENSDART00000001691
tdh2
L-threonine dehydrogenase 2
chr14_-_5678457 2.10 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr7_+_27317174 2.09 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr3_+_4346854 2.05 ENSDART00000004273
si:dkey-73p2.3
si:dkey-73p2.3
chr23_+_21663631 2.00 ENSDART00000066125
dhrs3a
dehydrogenase/reductase (SDR family) member 3a
chr1_+_26099250 1.99 ENSDART00000054205
ndufb6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
chr10_-_8129175 1.97 ENSDART00000133921
ndufa9b
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9b
chr19_-_7291733 1.96 ENSDART00000015559
sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr12_+_42574148 1.95 ENSDART00000157855
ebf3a
early B cell factor 3a
chr19_+_12583577 1.94 ENSDART00000151508
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr6_-_49170390 1.91 ENSDART00000182255
ngfb
nerve growth factor b (beta polypeptide)
chr10_+_9595575 1.90 ENSDART00000091780
ENSDART00000184287
rc3h2
ring finger and CCCH-type domains 2
chr17_+_44697604 1.90 ENSDART00000156625
pgfb
placental growth factor b
chr14_+_16813816 1.89 ENSDART00000161201
limch1b
LIM and calponin homology domains 1b
chr15_-_33904831 1.89 ENSDART00000164333
ENSDART00000165404
mag
myelin associated glycoprotein
chr20_-_27330383 1.88 ENSDART00000153277
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr7_+_2228276 1.86 ENSDART00000064294
si:dkey-187j14.4
si:dkey-187j14.4
chr25_+_35304903 1.86 ENSDART00000034313
ENSDART00000187659
gas2a
growth arrest-specific 2a
chr23_-_20002459 1.85 ENSDART00000163396
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr9_+_2507526 1.85 ENSDART00000166579
wipf1a
WAS/WASL interacting protein family, member 1a
chr12_-_684200 1.85 ENSDART00000152122
si:ch211-176g6.2
si:ch211-176g6.2
chr17_+_33415319 1.84 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr14_+_7048930 1.84 ENSDART00000109138
hbegfa
heparin-binding EGF-like growth factor a
chr3_+_30980852 1.82 ENSDART00000028529
prf1.1
perforin 1.1
chr1_+_5275811 1.78 ENSDART00000189676
spry2
sprouty RTK signaling antagonist 2
chr7_-_2143313 1.78 ENSDART00000173871
si:cabz01007807.1
si:cabz01007807.1
chr21_-_10773344 1.77 ENSDART00000063244
grp
gastrin-releasing peptide
chr9_+_33145522 1.76 ENSDART00000005879
atp5po
ATP synthase peripheral stalk subunit OSCP
chr24_-_3304664 1.75 ENSDART00000183168
sugct
succinyl-CoA:glutarate-CoA transferase
chr21_+_11560153 1.74 ENSDART00000065842
cd8a
CD8a molecule
chr3_+_41922114 1.74 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_43787616 1.73 ENSDART00000179758
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr7_-_3807658 1.73 ENSDART00000126799
ENSDART00000104372
zgc:195077
zgc:195077
chr12_-_30548244 1.72 ENSDART00000193616
zgc:158404
zgc:158404
chr11_+_6456146 1.72 ENSDART00000036939
gadd45ba
growth arrest and DNA-damage-inducible, beta a
chr20_-_34292607 1.70 ENSDART00000144705
hmcn1
hemicentin 1
chr21_+_42713845 1.70 ENSDART00000166927
si:ch1073-204b8.1
si:ch1073-204b8.1
chr9_-_54304684 1.69 ENSDART00000109512
il13
interleukin 13
chr17_+_33415542 1.69 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr13_+_25412307 1.68 ENSDART00000175339
calhm1
calcium homeostasis modulator 1
chr20_+_33534038 1.65 ENSDART00000029206
kcnf1a
potassium voltage-gated channel, subfamily F, member 1a
chr21_+_13387965 1.65 ENSDART00000134347
zgc:113162
zgc:113162
chr16_-_42151909 1.64 ENSDART00000160950
dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr22_+_12431608 1.63 ENSDART00000108609
rnd3a
Rho family GTPase 3a
chr15_-_33925851 1.62 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr2_+_3428357 1.61 ENSDART00000125967
CU633991.1

chr5_+_20437124 1.59 ENSDART00000159001
tmem119a
transmembrane protein 119a
chr25_-_20238793 1.59 ENSDART00000145987
dnm1l
dynamin 1-like
chr19_-_40199081 1.59 ENSDART00000051970
ENSDART00000151079
grn2
granulin 2
chr10_+_35347993 1.58 ENSDART00000131350
si:dkey-259j3.5
si:dkey-259j3.5
chr6_-_19168640 1.58 ENSDART00000163183
si:ch211-188c18.1
si:ch211-188c18.1
chr13_-_36391496 1.58 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr3_-_3209432 1.57 ENSDART00000140635
si:ch211-229i14.2
si:ch211-229i14.2
chr7_+_34549377 1.56 ENSDART00000191814
fhod1
formin homology 2 domain containing 1
chr2_-_50053006 1.54 ENSDART00000083654
si:ch211-106n13.3
si:ch211-106n13.3
chr20_-_34292285 1.53 ENSDART00000020389
hmcn1
hemicentin 1
chr8_-_51579286 1.52 ENSDART00000147878
ankrd39
ankyrin repeat domain 39
chr7_+_17816623 1.51 ENSDART00000173963
eml3
echinoderm microtubule associated protein like 3
chr22_-_15693085 1.46 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr12_+_23762966 1.45 ENSDART00000152942
ENSDART00000181725
jcada
junctional cadherin 5 associated a
chr14_-_3268155 1.44 ENSDART00000177244
pdgfrb
platelet-derived growth factor receptor, beta polypeptide
chr3_-_34084387 1.44 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr2_-_2642476 1.44 ENSDART00000124032
serbp1b
SERPINE1 mRNA binding protein 1b
chr7_-_20731078 1.43 ENSDART00000188267
chd3
chromodomain helicase DNA binding protein 3
chr24_-_2900511 1.42 ENSDART00000185674
fam69c
family with sequence similarity 69, member C
chr9_-_1939232 1.42 ENSDART00000146131
hoxd3a
homeobox D3a
chr14_+_26229056 1.41 ENSDART00000179045
LO018208.1

chr6_-_54107269 1.41 ENSDART00000190017
hyal2a
hyaluronoglucosaminidase 2a
chr16_-_51299061 1.39 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr2_+_6885852 1.38 ENSDART00000016607
rgs5b
regulator of G protein signaling 5b
chr25_-_19224298 1.37 ENSDART00000149917
acanb
aggrecan b
chr17_-_23412705 1.37 ENSDART00000126995
si:ch211-149k12.3
si:ch211-149k12.3
chr13_+_52061034 1.34 ENSDART00000170383
CABZ01089777.1

chr2_+_56012016 1.33 ENSDART00000146160
ENSDART00000188702
loxl5b
lysyl oxidase-like 5b
chr15_-_47193564 1.33 ENSDART00000172453
LSAMP
limbic system-associated membrane protein
chr23_+_642001 1.32 ENSDART00000030643
ENSDART00000124850
irf10
interferon regulatory factor 10

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
2.7 19.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
2.2 6.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.5 10.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 12.4 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.1 5.5 GO:0003210 cardiac atrium formation(GO:0003210)
1.0 3.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.7 2.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 2.9 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.7 2.8 GO:0030091 protein repair(GO:0030091)
0.7 2.0 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.5 2.7 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.5 1.6 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.5 14.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.5 2.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.4 1.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.4 2.6 GO:0055016 hypochord development(GO:0055016)
0.4 3.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 1.2 GO:0090131 mesenchyme migration(GO:0090131)
0.4 4.8 GO:0007525 somatic muscle development(GO:0007525)
0.4 2.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.4 1.5 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.4 2.2 GO:0051883 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.4 1.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.4 1.4 GO:0014909 smooth muscle cell migration(GO:0014909)
0.3 1.0 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.3 3.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.3 11.5 GO:0030199 collagen fibril organization(GO:0030199)
0.3 5.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 4.7 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.3 0.6 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.3 1.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3 1.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 2.1 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.3 13.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 2.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.3 0.8 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 1.0 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.2 1.7 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.2 1.0 GO:0014060 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.2 1.6 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.2 1.1 GO:0007624 ultradian rhythm(GO:0007624)
0.2 0.9 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.2 0.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 1.3 GO:0055014 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.2 2.1 GO:0060612 adipose tissue development(GO:0060612)
0.2 1.8 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 3.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 9.8 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 3.4 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.1 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 3.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 1.8 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.2 1.9 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 12.5 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.2 2.3 GO:0032264 IMP salvage(GO:0032264)
0.2 1.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 2.2 GO:0098868 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.3 GO:0042407 cristae formation(GO:0042407)
0.2 2.0 GO:0042572 retinol metabolic process(GO:0042572)
0.2 4.6 GO:0006826 iron ion transport(GO:0006826)
0.2 0.5 GO:0003403 optic vesicle formation(GO:0003403)
0.1 2.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 2.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 7.3 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.8 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 3.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 2.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 5.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 3.0 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 0.4 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.9 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 6.3 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.4 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.6 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 3.2 GO:0071711 basement membrane organization(GO:0071711)
0.1 3.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 4.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.0 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 5.5 GO:0051607 defense response to virus(GO:0051607)
0.1 2.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 8.2 GO:0001708 cell fate specification(GO:0001708)
0.1 1.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 4.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.6 GO:0001706 endoderm formation(GO:0001706)
0.1 0.8 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 1.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.9 GO:0046686 response to cadmium ion(GO:0046686)
0.1 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 3.9 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 1.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 4.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 3.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.7 GO:0098943 positive regulation of synaptic transmission, glutamatergic(GO:0051968) neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 1.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 8.2 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.1 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.0 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 1.8 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 1.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.4 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.1 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.5 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:1901653 cellular response to peptide hormone stimulus(GO:0071375) cellular response to peptide(GO:1901653)
0.0 0.8 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 3.4 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 2.4 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.0 0.2 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 1.9 GO:0016460 myosin II complex(GO:0016460)
0.4 12.9 GO:0031672 A band(GO:0031672)
0.4 2.0 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 0.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 12.4 GO:0005861 troponin complex(GO:0005861)
0.3 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 5.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 1.8 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 3.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 25.1 GO:0030017 sarcomere(GO:0030017)
0.2 2.3 GO:0061617 MICOS complex(GO:0061617)
0.2 25.6 GO:0016459 myosin complex(GO:0016459)
0.2 4.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 6.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 7.2 GO:0016605 PML body(GO:0016605)
0.2 2.4 GO:0030315 T-tubule(GO:0030315)
0.2 3.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 4.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 3.0 GO:0005581 collagen trimer(GO:0005581)
0.1 1.2 GO:0005869 dynactin complex(GO:0005869)
0.1 25.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 8.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.7 GO:0005839 proteasome core complex(GO:0005839)
0.1 4.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.1 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.7 GO:0000243 commitment complex(GO:0000243)
0.1 1.7 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 3.3 GO:0005884 actin filament(GO:0005884)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0042383 sarcolemma(GO:0042383)
0.0 0.6 GO:0044447 axoneme part(GO:0044447)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.6 GO:0005769 early endosome(GO:0005769)
0.0 3.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 17.6 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0005521 lamin binding(GO:0005521)
1.6 4.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
1.5 4.6 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.5 19.1 GO:0004017 adenylate kinase activity(GO:0004017)
1.4 8.1 GO:0004743 pyruvate kinase activity(GO:0004743)
1.1 12.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.1 4.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.0 3.0 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.8 2.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 2.3 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.7 2.2 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.7 7.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 2.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.6 5.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 2.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4 1.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 2.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.4 2.8 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.4 1.6 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.4 1.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.4 1.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 5.9 GO:0033691 sialic acid binding(GO:0033691)
0.3 10.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 1.1 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.3 2.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 2.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 4.2 GO:0002039 p53 binding(GO:0002039)
0.2 1.8 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 2.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 5.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 3.8 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.9 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 2.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 7.1 GO:0003823 antigen binding(GO:0003823)
0.1 25.7 GO:0003774 motor activity(GO:0003774)
0.1 1.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 3.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.7 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 1.1 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 2.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 5.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 2.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 6.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 6.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 3.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.0 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 6.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 12.8 GO:0003779 actin binding(GO:0003779)
0.0 0.8 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 5.5 GO:0008017 microtubule binding(GO:0008017)
0.0 38.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 7.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 3.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 3.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 3.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 3.4 PID ALK2 PATHWAY ALK2 signaling events
0.2 1.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 2.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 6.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 5.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 9.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 19.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7 4.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 2.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 6.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 3.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 4.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 1.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 1.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 6.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 5.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo