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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for isl1+isl1l

Z-value: 0.69

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Transcription factors associated with isl1+isl1l

Gene Symbol Gene ID Gene Info
isl1
ENSDARG00000004023 ISL LIM homeobox 1
isl1l
ENSDARG00000021055 islet1, like
isl1l
ENSDARG00000110204 islet1, like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
isl1dr11_v1_chr5_-_40734045_407340450.112.7e-01Click!
isl1ldr11_v1_chr10_+_8680730_8680730-0.084.3e-01Click!

Activity profile of isl1+isl1l motif

Sorted Z-values of isl1+isl1l motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_11457500 6.63 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr5_-_30615901 4.97 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr10_-_2943474 4.04 ENSDART00000188698
oclna
occludin a
chr15_-_12011202 3.97 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
si:dkey-202l22.6
chr5_-_41831646 3.81 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr1_+_41588170 3.69 ENSDART00000139175
si:dkey-56e3.2
si:dkey-56e3.2
chr1_-_59348118 3.61 ENSDART00000170901
cyp3a65
cytochrome P450, family 3, subfamily A, polypeptide 65
chr8_+_53064920 3.60 ENSDART00000164823
nadka
NAD kinase a
chr14_+_21222287 3.57 ENSDART00000159905
si:ch211-175m2.4
si:ch211-175m2.4
chr17_+_42274825 3.42 ENSDART00000020156
pax1a
paired box 1a
chr4_+_7508316 3.36 ENSDART00000170924
ENSDART00000170933
ENSDART00000164985
ENSDART00000167571
ENSDART00000158843
ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr22_+_19220459 3.35 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr17_+_33375469 3.18 ENSDART00000032827
zgc:162964
zgc:162964
chr13_+_12456412 3.11 ENSDART00000057762
dapp1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr7_+_13988075 3.07 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr1_-_25679339 2.99 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr4_+_76705830 2.93 ENSDART00000064312
ms4a17a.7
membrane-spanning 4-domains, subfamily A, member 17A.7
chr24_-_32665283 2.93 ENSDART00000038364
ca2
carbonic anhydrase II
chr14_-_36799280 2.61 ENSDART00000168615
rnf130
ring finger protein 130
chr19_+_10331325 2.56 ENSDART00000143930
tmem238a
transmembrane protein 238a
chr10_+_35352435 2.53 ENSDART00000123936
si:dkey-259j3.5
si:dkey-259j3.5
chr17_+_39741926 2.37 ENSDART00000154996
ENSDART00000154599
si:dkey-229e3.2
si:dkey-229e3.2
chr13_-_36391496 2.37 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr1_-_45146834 2.35 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr3_+_15505275 2.31 ENSDART00000141714
nupr1
nuclear protein 1
chr23_+_26142807 2.25 ENSDART00000158878
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr17_-_2036850 2.18 ENSDART00000186048
ENSDART00000188838
ENSDART00000186423
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr10_+_35358675 2.17 ENSDART00000193263
si:dkey-259j3.5
si:dkey-259j3.5
chr13_+_46941930 2.16 ENSDART00000056962
fbxo5
F-box protein 5
chr23_+_26142613 2.14 ENSDART00000165046
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr5_-_41838354 2.06 ENSDART00000146793
si:dkey-65b12.6
si:dkey-65b12.6
chr17_+_6563307 1.91 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr12_-_36521767 1.89 ENSDART00000110290
unc13d
unc-13 homolog D (C. elegans)
chr4_-_75707991 1.87 ENSDART00000166358
ENSDART00000160021
si:dkey-165o8.2
si:dkey-165o8.2
chr9_-_41507712 1.82 ENSDART00000135821
mfsd6b
major facilitator superfamily domain containing 6b
chr22_-_31020690 1.76 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr22_-_10121880 1.75 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr8_+_18830759 1.72 ENSDART00000089079
mpnd
MPN domain containing
chr6_-_8580857 1.69 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr14_+_20893065 1.65 ENSDART00000079452
lygl1
lysozyme g-like 1
chr22_-_36875264 1.65 ENSDART00000137548
kng1
kininogen 1
chr18_-_35459996 1.63 ENSDART00000141023
itpkcb
inositol-trisphosphate 3-kinase Cb
chr7_-_34192834 1.62 ENSDART00000125131
smad6a
SMAD family member 6a
chr15_+_32642878 1.58 ENSDART00000159932
trpc4b
transient receptor potential cation channel, subfamily C, member 4b
chr23_+_20431388 1.58 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr3_+_22377312 1.54 ENSDART00000155597
arhgap27l
Rho GTPase activating protein 27, like
chr16_-_46619967 1.53 ENSDART00000158341
tmem176l.3a
transmembrane protein 176l.3a
chr12_-_44307963 1.49 ENSDART00000161009
si:ch73-329n5.1
si:ch73-329n5.1
chr7_+_19482084 1.49 ENSDART00000173873
si:ch211-212k18.7
si:ch211-212k18.7
chr12_-_13205854 1.46 ENSDART00000077829
pelo
pelota mRNA surveillance and ribosome rescue factor
chr22_-_17653143 1.46 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr20_+_34770197 1.44 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr2_+_36112273 1.44 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr19_-_6193448 1.43 ENSDART00000151405
erf
Ets2 repressor factor
chr16_-_22192006 1.41 ENSDART00000163338
il6r
interleukin 6 receptor
chr3_-_32956808 1.41 ENSDART00000183902
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr10_-_36808348 1.40 ENSDART00000099320
dhrs13a.1
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr5_+_32345187 1.39 ENSDART00000147132
c9
complement component 9
chr8_-_14121634 1.38 ENSDART00000184946
bgna
biglycan a
chr4_+_2230701 1.38 ENSDART00000080439
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr15_-_25518084 1.37 ENSDART00000158594
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr4_+_9478500 1.35 ENSDART00000030738
lmf2b
lipase maturation factor 2b
chr8_+_21254192 1.29 ENSDART00000167718
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr7_-_54679595 1.27 ENSDART00000165320
ccnd1
cyclin D1
chr23_-_45398622 1.27 ENSDART00000053571
ENSDART00000149464
zgc:100911
zgc:100911
chr6_-_27123327 1.25 ENSDART00000073881
agxta
alanine-glyoxylate aminotransferase a
chr15_-_44052927 1.24 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr5_-_64203101 1.24 ENSDART00000029364
ak5l
adenylate kinase 5, like
chr10_+_38708099 1.24 ENSDART00000172306
tmprss2
transmembrane protease, serine 2
chr6_-_53326421 1.21 ENSDART00000191740
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr13_+_15701849 1.21 ENSDART00000003517
trmt61a
tRNA methyltransferase 61A
chr22_-_3299100 1.20 ENSDART00000160305
si:zfos-943e10.1
si:zfos-943e10.1
chr22_-_621888 1.19 ENSDART00000135829
srsf3b
serine/arginine-rich splicing factor 3b
chr20_-_35012093 1.18 ENSDART00000062761
cnstb
consortin, connexin sorting protein b
chr10_+_32104305 1.18 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr6_+_22326624 1.17 ENSDART00000020333
rae1
ribonucleic acid export 1
chr13_-_36582341 1.15 ENSDART00000137335
lgals3a
lectin, galactoside binding soluble 3a
chr1_-_43727012 1.15 ENSDART00000181064
bdh2
3-hydroxybutyrate dehydrogenase, type 2
chr3_-_56871984 1.14 ENSDART00000189908
ENSDART00000183146
ENSDART00000183087
zgc:112148
zgc:112148
chr14_-_30876299 1.12 ENSDART00000180305
ubl3b
ubiquitin-like 3b
chr5_+_22393501 1.11 ENSDART00000185276
si:dkey-27p18.7
si:dkey-27p18.7
chr12_-_19028046 1.11 ENSDART00000142253
ENSDART00000078484
rangap1b
Ran GTPase activating protein 1b
chr23_+_36653376 1.10 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr12_+_10062953 1.10 ENSDART00000148689
slc4a1b
solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
chr1_+_1915967 1.09 ENSDART00000131463
si:ch211-132g1.1
si:ch211-132g1.1
chr25_-_10769039 1.08 ENSDART00000186758
ENSDART00000121724
lrp5
low density lipoprotein receptor-related protein 5
chr11_+_705727 1.08 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr20_+_23440632 1.08 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr2_-_50719170 1.08 ENSDART00000074943
xcr1b.1
chemokine (C motif) receptor 1b, duplicate 1
chr20_-_22464250 1.07 ENSDART00000165904
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr4_-_890220 1.07 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr1_+_59328030 1.07 ENSDART00000172464
CABZ01052576.1

chr19_-_47570672 1.06 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr8_-_30338872 1.05 ENSDART00000137583
dock8
dedicator of cytokinesis 8
chr25_+_30131055 1.04 ENSDART00000152705
api5
apoptosis inhibitor 5
chr22_+_19290199 1.04 ENSDART00000148173
si:dkey-21e2.15
si:dkey-21e2.15
chr14_-_32631013 1.04 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr20_+_2039518 1.03 ENSDART00000043157
CABZ01088134.1

chr15_+_11814969 1.03 ENSDART00000127248
FO704748.1

chr5_+_31168096 1.03 ENSDART00000086443
ENSDART00000192271
atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr13_-_337318 1.02 ENSDART00000166175
zgc:171534
zgc:171534
chr16_+_52999778 1.02 ENSDART00000011506
nkd2a
naked cuticle homolog 2a
chr19_+_8612839 1.00 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr16_-_29387215 0.99 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr20_-_45709990 0.99 ENSDART00000027482
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr6_-_40581376 0.99 ENSDART00000185412
tspo
translocator protein
chr5_+_25762271 0.96 ENSDART00000181323
tmem2
transmembrane protein 2
chr16_-_30903930 0.96 ENSDART00000143996
dennd3b
DENN/MADD domain containing 3b
chr17_+_47090497 0.95 ENSDART00000169038
ENSDART00000159292
zgc:103755
zgc:103755
chr14_-_31856819 0.95 ENSDART00000003345
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr14_-_36437249 0.94 ENSDART00000016728
aga
aspartylglucosaminidase
chr14_+_16287968 0.94 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr3_-_8012847 0.93 ENSDART00000169673
si:ch211-175l6.1
si:ch211-175l6.1
chr21_+_31253048 0.93 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr22_-_28644517 0.93 ENSDART00000189538
jagn1b
jagunal homolog 1b
chr9_+_54695981 0.93 ENSDART00000183605
rab9a
RAB9A, member RAS oncogene family
chr4_+_71086017 0.92 ENSDART00000159113
si:dkeyp-80d11.10
si:dkeyp-80d11.10
chr12_+_27034760 0.92 ENSDART00000181170
ENSDART00000153054
fbrs
fibrosin
chr24_-_33308045 0.92 ENSDART00000149711
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr3_-_8765165 0.91 ENSDART00000191131
CABZ01058333.1

chr1_-_9486214 0.90 ENSDART00000137821
micall2b
mical-like 2b
chr21_+_26522571 0.90 ENSDART00000134617
adssl
adenylosuccinate synthase, like
chr10_-_10018120 0.90 ENSDART00000132375
strbp
spermatid perinuclear RNA binding protein
chr22_+_6149121 0.89 ENSDART00000134067
si:dkey-19a16.5
si:dkey-19a16.5
chr3_-_36209936 0.89 ENSDART00000175208
csnk1da
casein kinase 1, delta a
chr17_+_3124129 0.88 ENSDART00000155323
zgc:136872
zgc:136872
chr4_-_12930086 0.88 ENSDART00000013604
lemd3
LEM domain containing 3
chr9_+_8942258 0.87 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr11_-_438294 0.87 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr2_+_20604775 0.87 ENSDART00000131501
olfml2bb
olfactomedin-like 2Bb
chr8_+_20140321 0.86 ENSDART00000012120
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr15_-_43625549 0.86 ENSDART00000168589
ctsc
cathepsin C
chr15_-_39969988 0.86 ENSDART00000146054
rps5
ribosomal protein S5
chr13_-_42536642 0.85 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr23_+_20431140 0.85 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr16_-_55259199 0.85 ENSDART00000161130
iqgap3
IQ motif containing GTPase activating protein 3
chr12_+_27034594 0.84 ENSDART00000111679
fbrs
fibrosin
chr20_-_40360571 0.82 ENSDART00000144768
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr11_+_27347076 0.82 ENSDART00000173383
fbln2
fibulin 2
chr13_+_33689740 0.81 ENSDART00000161904
ephx5
epoxide hydrolase 5
chr9_-_14137295 0.81 ENSDART00000127640
ENSDART00000189018
ENSDART00000188985
ttll4
tubulin tyrosine ligase-like family, member 4
chr23_-_31372639 0.78 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr14_+_23709134 0.76 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
gnpda1
glucosamine-6-phosphate deaminase 1
chr16_+_53203370 0.75 ENSDART00000154669
si:ch211-269k10.2
si:ch211-269k10.2
chr12_+_22672323 0.73 ENSDART00000123808
ENSDART00000159864
cdca9
cell division cycle associated 9
chr6_-_436658 0.73 ENSDART00000191515
grap2b
GRB2-related adaptor protein 2b
chr9_+_3283608 0.73 ENSDART00000192275
hat1
histone acetyltransferase 1
chr1_+_9994811 0.72 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr19_-_7272921 0.72 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr12_-_13205572 0.72 ENSDART00000152670
pelo
pelota mRNA surveillance and ribosome rescue factor
chr18_+_7612438 0.72 ENSDART00000175288
odf3b
outer dense fiber of sperm tails 3B
chr9_-_35633827 0.72 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr7_+_38897836 0.72 ENSDART00000024330
creb3l1
cAMP responsive element binding protein 3-like 1
chr5_-_19006290 0.69 ENSDART00000137022
golga3
golgin A3
chr23_-_38497705 0.69 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr15_-_15983428 0.69 ENSDART00000115129
synrg
synergin, gamma
chr22_-_16755885 0.69 ENSDART00000036467
patj
PATJ, crumbs cell polarity complex component
chr12_+_28910762 0.68 ENSDART00000076342
ENSDART00000160939
ENSDART00000076572
rnf40
ring finger protein 40
chr5_-_33281046 0.68 ENSDART00000051344
ENSDART00000138116
surf6
surfeit 6
chr24_+_36636208 0.67 ENSDART00000139211
si:ch73-334d15.4
si:ch73-334d15.4
chr7_+_3872189 0.66 ENSDART00000064221
si:dkey-88n24.5
si:dkey-88n24.5
chr18_+_48953963 0.66 ENSDART00000158104
SHKBP1
SH3KBP1 binding protein 1
chr11_-_1400507 0.62 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
rpl29
ribosomal protein L29
chr21_+_2506013 0.61 ENSDART00000162351
hmgcrb
3-hydroxy-3-methylglutaryl-CoA reductase b
chr4_-_14192254 0.59 ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr7_+_26998169 0.59 ENSDART00000128110
ENSDART00000101018
caprin1a
cell cycle associated protein 1a
chr20_+_29209926 0.59 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr14_+_1240419 0.59 ENSDART00000181248
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr20_-_45772306 0.58 ENSDART00000062092
trmt6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr3_+_8224622 0.58 ENSDART00000138670
si:ch73-379f5.5
si:ch73-379f5.5
chr5_-_36597612 0.57 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr20_-_25522911 0.57 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr6_+_15268685 0.57 ENSDART00000128090
ENSDART00000154417
ecrg4b
esophageal cancer related gene 4b
chr21_-_30408775 0.57 ENSDART00000101037
nhp2
NHP2 ribonucleoprotein homolog (yeast)
chr5_-_13076779 0.57 ENSDART00000192826
ypel1
yippee-like 1
chr2_+_10007113 0.55 ENSDART00000155213
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr13_-_11971148 0.55 ENSDART00000066230
ENSDART00000185614
ARL3 (1 of many)
zgc:110197
chr18_+_20677090 0.54 ENSDART00000060243
cftr
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr15_-_1962326 0.54 ENSDART00000179669
dock10
dedicator of cytokinesis 10
chr20_-_5400395 0.53 ENSDART00000168103
snw1
SNW domain containing 1
chr3_-_23513155 0.53 ENSDART00000170200
BX682558.1

chr22_-_26852516 0.53 ENSDART00000005829
gde1
glycerophosphodiester phosphodiesterase 1
chr14_-_1454045 0.52 ENSDART00000161460
pmt
phosphoethanolamine methyltransferase
chr3_-_18737126 0.52 ENSDART00000055767
e4f1
E4F transcription factor 1
chr11_-_37997419 0.52 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr25_+_32390794 0.52 ENSDART00000012600
galk2
galactokinase 2
chr15_+_1199407 0.52 ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr2_-_10821053 0.52 ENSDART00000056034
rpap2
RNA polymerase II associated protein 2
chr5_+_58687541 0.52 ENSDART00000083015
ENSDART00000181902
ccdc84
coiled-coil domain containing 84
chr5_+_66250856 0.51 ENSDART00000132789
secisbp2
SECIS binding protein 2
chr1_-_25144439 0.51 ENSDART00000132355
fbxw7
F-box and WD repeat domain containing 7
chr3_-_11008532 0.51 ENSDART00000165086
CR382337.3

chr16_+_9400661 0.50 ENSDART00000146174
ice1
KIAA0947-like (H. sapiens)
chr11_-_18107447 0.50 ENSDART00000187376
qrich1
glutamine-rich 1
chr4_-_15103646 0.50 ENSDART00000138183
ENSDART00000181044
nrf1
nuclear respiratory factor 1
chr4_-_71214516 0.50 ENSDART00000169997
si:ch211-205a14.7
si:ch211-205a14.7
chr16_-_36979592 0.48 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr9_+_30478768 0.48 ENSDART00000101097
acp6
acid phosphatase 6, lysophosphatidic
chr18_-_50839033 0.47 ENSDART00000169773
ddb1
damage-specific DNA binding protein 1
chr16_+_9762261 0.47 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of isl1+isl1l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.6 1.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.5 2.2 GO:0032790 ribosome disassembly(GO:0032790)
0.5 2.2 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.5 3.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.5 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.5 1.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.4 1.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.1 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.3 0.9 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.3 0.8 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3 0.8 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 1.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.5 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.2 1.7 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.2 1.6 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 0.9 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 0.9 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 1.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 1.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.2 3.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 1.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.2 1.2 GO:0006545 glycine biosynthetic process(GO:0006545)
0.2 1.4 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 3.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.2 0.6 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 0.5 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.2 1.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 0.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.5 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.2 1.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2 0.5 GO:0070417 cellular response to cold(GO:0070417)
0.2 1.0 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 2.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 1.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.9 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.6 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.9 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 1.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 2.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 1.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.3 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 1.4 GO:0014823 response to activity(GO:0014823)
0.1 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.3 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 1.4 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 3.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 2.9 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.3 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 1.6 GO:0006828 manganese ion transport(GO:0006828)
0.1 2.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.6 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 4.2 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 1.0 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.3 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.8 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.8 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.6 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 4.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.5 GO:0050821 protein stabilization(GO:0050821)
0.0 4.5 GO:0006914 autophagy(GO:0006914)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.0 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 1.1 GO:0009306 protein secretion(GO:0009306)
0.0 0.2 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 1.2 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.1 GO:2000047 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.3 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.5 1.4 GO:0044218 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.4 1.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 1.8 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 0.9 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.9 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 3.4 GO:0005861 troponin complex(GO:0005861)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 4.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 1.1 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 2.7 GO:0005581 collagen trimer(GO:0005581)
0.0 3.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.4 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.5 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 6.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0022627 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 3.6 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 1.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.4 1.7 GO:0003796 lysozyme activity(GO:0003796)
0.4 1.8 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3 1.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 3.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.3 1.2 GO:0071253 connexin binding(GO:0071253)
0.3 0.8 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.3 1.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.3 0.8 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.2 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 1.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.7 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 3.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.0 GO:0070122 isopeptidase activity(GO:0070122)
0.1 3.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 2.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.7 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.9 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.8 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 4.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 8.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.5 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.2 GO:0004519 endonuclease activity(GO:0004519)
0.0 4.0 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 1.3 GO:0019955 cytokine binding(GO:0019955)
0.0 0.9 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.5 PID E2F PATHWAY E2F transcription factor network
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G