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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for junba+junbb

Z-value: 2.39

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Transcription factors associated with junba+junbb

Gene Symbol Gene ID Gene Info
junba
ENSDARG00000074378 JunB proto-oncogene, AP-1 transcription factor subunit a
junbb
ENSDARG00000104773 JunB proto-oncogene, AP-1 transcription factor subunit b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
junbadr11_v1_chr1_-_51734524_51734535-0.293.9e-03Click!
junbbdr11_v1_chr3_-_7656059_7656059-0.056.2e-01Click!

Activity profile of junba+junbb motif

Sorted Z-values of junba+junbb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_12385308 62.94 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr6_+_27667359 41.60 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr20_+_34913069 39.22 ENSDART00000007584
snap25a
synaptosomal-associated protein, 25a
chr14_+_34486629 32.37 ENSDART00000131861
tmsb2
thymosin beta 2
chr2_-_11512819 32.08 ENSDART00000142013
penka
proenkephalin a
chr16_-_17207754 29.24 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr10_-_39011514 28.95 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr3_-_36115339 27.94 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
rab11fip4a
RAB11 family interacting protein 4 (class II) a
chr16_-_43026273 26.09 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
si:dkey-7j14.5
chr1_-_22861348 25.78 ENSDART00000139412
SMIM18
si:dkey-92j12.6
chr1_-_38756870 25.77 ENSDART00000130324
ENSDART00000148404
gpm6ab
glycoprotein M6Ab
chr19_+_24882845 25.03 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr8_+_39607466 24.91 ENSDART00000097427
msi1
musashi RNA-binding protein 1
chr3_+_32403758 24.52 ENSDART00000156982
si:ch211-195b15.8
si:ch211-195b15.8
chr2_-_42415902 24.36 ENSDART00000142489
slco5a1b
solute carrier organic anion transporter family member 5A1b
chr1_-_51606552 24.29 ENSDART00000130828
cnrip1a
cannabinoid receptor interacting protein 1a
chr3_-_49566364 23.82 ENSDART00000161507
zgc:153426
zgc:153426
chr5_-_35301800 23.41 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr15_-_44512461 23.19 ENSDART00000155456
gria4a
glutamate receptor, ionotropic, AMPA 4a
chr18_-_38087875 22.72 ENSDART00000111301
luzp2
leucine zipper protein 2
chr18_+_21408794 22.48 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr16_-_43025885 21.88 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr9_+_219124 21.87 ENSDART00000161484
map3k12
mitogen-activated protein kinase kinase kinase 12
chr23_+_19590006 21.73 ENSDART00000021231
slmapb
sarcolemma associated protein b
chr19_+_10396042 21.26 ENSDART00000028048
ENSDART00000151735
necap1
NECAP endocytosis associated 1
chr6_-_31348999 21.03 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_+_27146671 20.23 ENSDART00000156792
kif1aa
kinesin family member 1Aa
chr20_+_27020201 20.18 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr15_-_12319065 20.02 ENSDART00000162973
ENSDART00000170543
fxyd6
FXYD domain containing ion transport regulator 6
chr24_-_7632187 19.98 ENSDART00000041714
atp6v0a1b
ATPase H+ transporting V0 subunit a1b
chr3_-_13147310 19.84 ENSDART00000160840
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_+_25064519 19.80 ENSDART00000016181
ndrg3a
ndrg family member 3a
chr8_+_23165749 19.53 ENSDART00000063057
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr18_+_16330025 19.51 ENSDART00000142353
nts
neurotensin
chr2_+_22694382 19.37 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr20_-_34801181 19.36 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr24_-_17444067 19.27 ENSDART00000155843
cntnap2a
contactin associated protein like 2a
chr12_-_19103490 19.03 ENSDART00000060561
csdc2a
cold shock domain containing C2, RNA binding a
chr4_+_13733838 18.92 ENSDART00000067166
ENSDART00000133157
cntn1b
contactin 1b
chr12_+_45200744 18.82 ENSDART00000098932
wbp2
WW domain binding protein 2
chr8_+_8845932 18.75 ENSDART00000112028
si:ch211-180f4.1
si:ch211-180f4.1
chr1_+_49266886 18.62 ENSDART00000137179
caly
calcyon neuron-specific vesicular protein
chr7_+_23907692 17.96 ENSDART00000045479
syt4
synaptotagmin IV
chr20_+_3108597 17.92 ENSDART00000133435
CEP170B (1 of many)
si:ch73-212j7.1
chr11_-_7320211 17.44 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr5_+_3501859 16.61 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr19_+_16222618 16.49 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr18_-_38088099 16.09 ENSDART00000146120
luzp2
leucine zipper protein 2
chr18_+_17663898 15.84 ENSDART00000021213
cpne2
copine II
chr21_+_22630297 15.78 ENSDART00000147175
si:dkeyp-69c1.7
si:dkeyp-69c1.7
chr22_+_11535131 15.74 ENSDART00000113930
npb
neuropeptide B
chr21_+_22630627 15.74 ENSDART00000193092
si:dkeyp-69c1.7
si:dkeyp-69c1.7
chr3_+_31933893 15.58 ENSDART00000146509
ENSDART00000139644
lin7b
lin-7 homolog B (C. elegans)
chr19_+_25649626 15.56 ENSDART00000146947
tac1
tachykinin 1
chr25_-_7686201 15.54 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
si:ch211-286c4.6
chr11_+_40649412 15.54 ENSDART00000043016
ENSDART00000134560
slc45a1
solute carrier family 45, member 1
chr9_+_11532025 15.34 ENSDART00000109037
cdk5r2b
cyclin-dependent kinase 5, regulatory subunit 2b (p39)
chr17_+_24722646 15.33 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr24_-_28711176 15.21 ENSDART00000105753
olfm3a
olfactomedin 3a
chr10_+_15777258 15.07 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr7_-_72605673 15.03 ENSDART00000123887
MAPK8IP1 (1 of many)
mitogen-activated protein kinase 8 interacting protein 1
chr24_+_34606966 14.77 ENSDART00000105477
lrrtm2
leucine rich repeat transmembrane neuronal 2
chr1_+_31864404 14.76 ENSDART00000075260
inab
internexin neuronal intermediate filament protein, alpha b
chr8_+_25959940 14.74 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr15_-_28200049 14.50 ENSDART00000004200
sarm1
sterile alpha and TIR motif containing 1
chr12_-_30443562 14.48 ENSDART00000020769
adrb1
adrenoceptor beta 1
chr17_-_26721007 14.43 ENSDART00000034580
calm1a
calmodulin 1a
chr8_+_23174137 14.29 ENSDART00000189470
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr21_-_43606502 14.28 ENSDART00000151030
si:ch73-362m14.4
si:ch73-362m14.4
chr16_+_14029283 14.20 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr12_-_33972798 14.20 ENSDART00000105545
arl3
ADP-ribosylation factor-like 3
chr25_-_23052707 14.18 ENSDART00000024633
dusp8a
dual specificity phosphatase 8a
chr3_+_15271943 14.14 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr25_+_16945348 14.13 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr17_+_12698532 14.04 ENSDART00000064509
ENSDART00000136830
stmn4l
stathmin-like 4, like
chr20_-_37522569 13.95 ENSDART00000177011
ENSDART00000058502
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr7_-_40993456 13.89 ENSDART00000031700
en2a
engrailed homeobox 2a
chr2_+_20332044 13.86 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr9_+_42095220 13.72 ENSDART00000148317
ENSDART00000134431
pcbp3
poly(rC) binding protein 3
chr7_+_19882066 13.63 ENSDART00000111144
TMEM151A
transmembrane protein 151A
chr17_-_35881841 13.63 ENSDART00000110040
sox11a
SRY (sex determining region Y)-box 11a
chr17_+_29345606 13.54 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr10_-_22249444 13.49 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr3_+_33367954 13.43 ENSDART00000103161
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr23_-_28141419 13.36 ENSDART00000133039
tac3a
tachykinin 3a
chr7_-_48805181 13.24 ENSDART00000015884
mfge8a
milk fat globule-EGF factor 8 protein a
chr8_+_28066063 13.17 ENSDART00000078533
kcnd3
potassium voltage-gated channel, Shal-related subfamily, member 3
chr10_+_15777064 13.14 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr20_-_18736281 13.13 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr15_+_28685892 12.78 ENSDART00000155815
ENSDART00000060244
nova2
neuro-oncological ventral antigen 2
chr13_-_33398735 12.78 ENSDART00000182601
ENSDART00000103628
btbd6a
BTB (POZ) domain containing 6a
chr2_-_27775236 12.71 ENSDART00000187983
XKR4
zgc:123035
chr2_+_25929619 12.52 ENSDART00000137746
slc7a14a
solute carrier family 7, member 14a
chr1_+_54908895 12.51 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr23_+_19590598 12.44 ENSDART00000170149
slmapb
sarcolemma associated protein b
chr14_-_7888748 12.42 ENSDART00000166293
ppp3cb
protein phosphatase 3, catalytic subunit, beta isozyme
chr19_-_10395683 12.38 ENSDART00000109488
zgc:194578
zgc:194578
chr13_+_15816573 12.37 ENSDART00000137061
klc1a
kinesin light chain 1a
chr2_+_20331445 12.34 ENSDART00000186880
plppr4a
phospholipid phosphatase related 4a
chr2_-_11912347 12.26 ENSDART00000023851
abhd3
abhydrolase domain containing 3
chr8_+_39634114 12.22 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr4_+_26496489 12.20 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr25_-_31863374 12.19 ENSDART00000028338
scamp5a
secretory carrier membrane protein 5a
chr7_-_39203799 12.19 ENSDART00000173727
chrm4a
cholinergic receptor, muscarinic 4a
chr6_+_33537267 12.18 ENSDART00000040334
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr22_+_12366516 12.15 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr1_+_40023640 12.14 ENSDART00000101623
lgi2b
leucine-rich repeat LGI family, member 2b
chr7_-_71434298 12.10 ENSDART00000180507
lgi2a
leucine-rich repeat LGI family, member 2a
chr1_-_40227166 11.96 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr5_-_23999777 11.82 ENSDART00000085969
map7d2a
MAP7 domain containing 2a
chr14_-_33454595 11.71 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr8_+_29267093 11.66 ENSDART00000077647
grid2
glutamate receptor, ionotropic, delta 2
chr5_-_41560874 11.61 ENSDART00000136702
dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr25_-_31763897 11.47 ENSDART00000041740
ubl7a
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr15_+_36115955 11.45 ENSDART00000032702
sst1.2
somatostatin 1, tandem duplicate 2
chr11_-_29623380 11.44 ENSDART00000162587
ENSDART00000193935
ENSDART00000191646
chd5
chromodomain helicase DNA binding protein 5
chr20_+_26095530 11.41 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr3_-_5964557 11.25 ENSDART00000184738
BX284638.1

chr6_+_13933464 11.05 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr22_-_38621438 10.81 ENSDART00000098330
nppc
natriuretic peptide C
chr18_+_16749091 10.78 ENSDART00000061265
rnf141
ring finger protein 141
chr7_-_51476276 10.75 ENSDART00000082464
nhsl2
NHS-like 2
chr23_-_637347 10.74 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr12_+_19305390 10.57 ENSDART00000183987
ENSDART00000066391
csnk1e
casein kinase 1, epsilon
chr18_-_21859019 10.57 ENSDART00000100885
nrn1la
neuritin 1-like a
chr20_+_19238382 10.56 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr25_-_37084032 10.50 ENSDART00000025494
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
chr13_+_4505079 10.45 ENSDART00000144312
pde10a
phosphodiesterase 10A
chr23_+_28582865 10.39 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr7_+_15872357 10.36 ENSDART00000165757
pax6b
paired box 6b
chr11_-_17713987 10.31 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr14_-_1955257 10.14 ENSDART00000193254
pcdh2g5
protocadherin 2 gamma 5
chr14_-_2318590 10.04 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr3_+_40576447 10.02 ENSDART00000083212
fscn1a
fascin actin-bundling protein 1a
chr13_+_12174937 9.97 ENSDART00000171683
gabrg1
gamma-aminobutyric acid type A receptor gamma1 subunit
chr13_+_17702853 9.84 ENSDART00000145438
si:dkey-27m7.4
si:dkey-27m7.4
chr18_-_22094102 9.69 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr5_-_46896541 9.69 ENSDART00000133240
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr9_-_31747106 9.67 ENSDART00000048469
ENSDART00000145204
ENSDART00000186889
nalcn
sodium leak channel, non-selective
chr9_-_18742704 9.64 ENSDART00000145401
tsc22d1
TSC22 domain family, member 1
chr20_-_39103119 9.64 ENSDART00000143379
rcan2
regulator of calcineurin 2
chr2_+_21090317 9.61 ENSDART00000109568
ENSDART00000139633
pip4k2ab
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr14_-_1958994 9.60 ENSDART00000161783
pcdh2g5
protocadherin 2 gamma 5
chr9_+_21535885 9.52 ENSDART00000141408
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr16_+_4055331 9.51 ENSDART00000128978
CR391998.1

chr11_+_15931188 9.48 ENSDART00000165768
ENSDART00000081098
draxin
dorsal inhibitory axon guidance protein
chr20_+_30490682 9.45 ENSDART00000184871
myt1la
myelin transcription factor 1-like, a
chr15_-_163586 9.45 ENSDART00000163597
SEPT4
septin-4
chr10_-_7858553 9.41 ENSDART00000182010
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr14_-_2050057 9.38 ENSDART00000112875
PCDHB15
protocadherin beta 15
chr12_+_7491690 9.36 ENSDART00000152564
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr19_+_45970692 9.19 ENSDART00000158781
si:ch211-153f2.7
si:ch211-153f2.7
chr17_+_8184649 9.19 ENSDART00000091818
tulp4b
tubby like protein 4b
chr10_+_29698467 9.16 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr10_+_22782522 9.08 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr25_-_8030113 9.05 ENSDART00000104674
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr1_+_51312752 8.99 ENSDART00000063938
mast1a
microtubule associated serine/threonine kinase 1a
chr3_+_32698424 8.98 ENSDART00000055340
fus
FUS RNA binding protein
chr17_+_18117029 8.92 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr13_+_24552254 8.89 ENSDART00000147907
lgalslb
lectin, galactoside-binding-like b
chr17_+_17955063 8.87 ENSDART00000104999
ccdc85ca
coiled-coil domain containing 85C, a
chr21_-_5856050 8.86 ENSDART00000115367
CABZ01071020.1

chr17_+_24320861 8.81 ENSDART00000179858
otx1
orthodenticle homeobox 1
chr5_-_20814576 8.77 ENSDART00000098682
ENSDART00000147639
si:ch211-225b11.1
si:ch211-225b11.1
chr8_+_28065803 8.74 ENSDART00000178481
kcnd3
potassium voltage-gated channel, Shal-related subfamily, member 3
chr9_-_18743012 8.71 ENSDART00000131626
tsc22d1
TSC22 domain family, member 1
chr2_-_5942115 8.67 ENSDART00000154489
tmem125b
transmembrane protein 125b
chr3_-_21137362 8.65 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr4_-_20081621 8.65 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr18_+_17428506 8.58 ENSDART00000100223
zgc:91860
zgc:91860
chr23_+_45584223 8.57 ENSDART00000149367
si:ch73-290k24.5
si:ch73-290k24.5
chr6_+_3004972 8.49 ENSDART00000186750
ENSDART00000183862
ENSDART00000191485
ENSDART00000171014
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr24_-_22702017 8.47 ENSDART00000179403
ctnnd2a
catenin (cadherin-associated protein), delta 2a
chr18_-_18850302 8.36 ENSDART00000131965
ENSDART00000167624
tgm2l
transglutaminase 2, like
chr7_-_26532089 8.32 ENSDART00000121698
senp3b
SUMO1/sentrin/SMT3 specific peptidase 3b
chr2_+_9821757 8.31 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr13_+_28854438 8.26 ENSDART00000193407
ENSDART00000189554
CU639469.1

chr20_+_522457 8.21 ENSDART00000138585
nt5dc1
5'-nucleotidase domain containing 1
chr22_+_18786797 8.19 ENSDART00000141864
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr24_-_35767501 8.16 ENSDART00000105680
ENSDART00000042290
ENSDART00000166264
dtna
dystrobrevin, alpha
chr20_-_46362606 7.88 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr10_+_5689510 7.85 ENSDART00000183217
ENSDART00000172632
pam
peptidylglycine alpha-amidating monooxygenase
chr12_-_10421955 7.82 ENSDART00000052004
zgc:153595
zgc:153595
chr10_-_26163989 7.79 ENSDART00000136472
trim3b
tripartite motif containing 3b
chr6_+_52350443 7.67 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr10_-_26744131 7.64 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr22_-_16443199 7.58 ENSDART00000006290
ENSDART00000193335
plekhb2
pleckstrin homology domain containing, family B (evectins) member 2
chr23_+_24611747 7.54 ENSDART00000134978
nckap5l
NCK-associated protein 5-like
chr2_-_16359042 7.54 ENSDART00000057216
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr9_+_35017702 7.49 ENSDART00000193640
gabpa
GA binding protein transcription factor, alpha subunit
chr18_-_20560007 7.31 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
si:ch211-238n5.4
chr15_+_1372343 7.29 ENSDART00000152285
schip1
schwannomin interacting protein 1
chr16_+_46459680 7.29 ENSDART00000101698
rpz3
rapunzel 3
chr13_+_12175724 7.19 ENSDART00000166053
gabrg1
gamma-aminobutyric acid type A receptor gamma1 subunit
chr9_+_6997861 7.14 ENSDART00000190491
inpp4aa
inositol polyphosphate-4-phosphatase type I Aa
chr22_-_600016 7.09 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr13_-_11035420 7.08 ENSDART00000108709
cep170aa
centrosomal protein 170Aa
chr12_+_33038757 7.08 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr1_-_54947592 7.06 ENSDART00000129710
crtac1a
cartilage acidic protein 1a
chr4_+_12111154 7.05 ENSDART00000036779
tmem178b
transmembrane protein 178B

Network of associatons between targets according to the STRING database.

First level regulatory network of junba+junbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.9 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
6.7 20.2 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
5.8 28.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
4.9 68.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
4.8 14.5 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
4.2 21.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
4.0 4.0 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
3.9 19.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
3.6 17.8 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
3.5 10.5 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
3.2 22.5 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
3.1 15.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
3.0 24.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
3.0 15.0 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
2.7 27.2 GO:0042989 sequestering of actin monomers(GO:0042989)
2.3 7.0 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
2.2 31.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
2.2 8.7 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
2.1 6.2 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
2.1 14.5 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
2.0 10.0 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
1.8 84.5 GO:0007019 microtubule depolymerization(GO:0007019)
1.7 6.9 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
1.7 11.7 GO:0070207 protein homotrimerization(GO:0070207)
1.6 4.8 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
1.6 39.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
1.6 6.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
1.5 6.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
1.5 21.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.5 10.4 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
1.5 21.9 GO:0000186 activation of MAPKK activity(GO:0000186)
1.4 36.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
1.4 20.0 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
1.4 39.2 GO:0016082 synaptic vesicle priming(GO:0016082)
1.3 7.8 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
1.3 43.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.3 9.1 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
1.3 3.8 GO:0003403 optic vesicle formation(GO:0003403)
1.2 28.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
1.2 19.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.2 13.6 GO:0046548 retinal rod cell development(GO:0046548)
1.2 7.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
1.2 4.8 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
1.2 9.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
1.1 19.4 GO:0032418 lysosome localization(GO:0032418)
1.1 5.6 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
1.1 12.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.1 3.3 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.1 5.4 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
1.1 2.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
1.0 4.2 GO:0090299 regulation of neural crest formation(GO:0090299)
1.0 4.0 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
1.0 2.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.0 6.9 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.0 9.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.0 21.1 GO:0045773 positive regulation of axon extension(GO:0045773)
1.0 5.7 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
1.0 14.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.9 8.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.9 12.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.9 3.6 GO:0010259 multicellular organism aging(GO:0010259)
0.9 2.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.8 2.5 GO:0061213 regulation of neurotransmitter uptake(GO:0051580) regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.8 14.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.8 2.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 5.4 GO:0035627 ceramide transport(GO:0035627)
0.8 9.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.7 17.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.7 5.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.7 3.6 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.7 2.9 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.7 6.5 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.7 4.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.7 4.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.7 5.9 GO:0008216 spermidine metabolic process(GO:0008216)
0.6 5.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.6 9.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.6 2.5 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.6 15.7 GO:0007631 feeding behavior(GO:0007631)
0.6 4.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 3.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.6 1.8 GO:0016584 nucleosome positioning(GO:0016584)
0.6 10.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.6 26.9 GO:0032456 endocytic recycling(GO:0032456)
0.6 3.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.6 32.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.6 20.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.6 6.2 GO:0072178 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.6 3.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.6 18.8 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.5 6.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.5 8.4 GO:0016926 protein desumoylation(GO:0016926)
0.5 4.7 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.5 3.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.5 14.6 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.5 3.5 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 7.4 GO:0042407 cristae formation(GO:0042407)
0.5 7.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.5 6.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.5 2.8 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.5 17.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.5 14.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 8.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.4 4.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.4 3.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.4 15.9 GO:0000266 mitochondrial fission(GO:0000266)
0.4 2.6 GO:1903826 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.4 4.3 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.4 4.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.4 5.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.4 5.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 29.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.4 3.2 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.4 8.4 GO:0018149 peptide cross-linking(GO:0018149)
0.4 1.1 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.4 4.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 3.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.4 1.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.4 1.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 35.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.3 1.7 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.3 31.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.3 19.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.3 0.9 GO:0080009 mRNA methylation(GO:0080009)
0.3 2.2 GO:0001839 neural plate morphogenesis(GO:0001839)
0.3 2.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 7.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.3 8.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.3 2.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 1.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 5.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.3 7.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.3 1.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 2.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.3 5.2 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.3 8.4 GO:0051085 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 5.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 3.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 1.2 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.2 6.3 GO:0007164 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.2 1.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 3.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 36.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 8.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 10.4 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 11.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.2 3.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.2 2.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 49.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.2 5.1 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.2 48.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 12.1 GO:0007098 centrosome cycle(GO:0007098)
0.2 3.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.2 1.5 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.2 2.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.2 14.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 12.2 GO:0001819 positive regulation of cytokine production(GO:0001819)
0.2 10.8 GO:0006338 chromatin remodeling(GO:0006338)
0.2 7.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 1.4 GO:0050771 negative regulation of axon extension(GO:0030517) negative regulation of axonogenesis(GO:0050771)
0.2 0.5 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.2 4.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 1.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 3.6 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 10.0 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.1 2.4 GO:0051897 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068) positive regulation of protein kinase B signaling(GO:0051897)
0.1 3.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.8 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218) ER-associated misfolded protein catabolic process(GO:0071712)
0.1 18.4 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 4.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 4.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.7 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 22.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 3.5 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.9 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 3.0 GO:0034250 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.1 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 20.2 GO:0030334 regulation of cell migration(GO:0030334)
0.1 4.5 GO:0016358 dendrite development(GO:0016358)
0.1 3.6 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 1.8 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 2.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.4 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 1.6 GO:0010043 response to zinc ion(GO:0010043)
0.1 4.6 GO:0051607 defense response to virus(GO:0051607)
0.1 4.3 GO:0006906 vesicle fusion(GO:0006906) organelle membrane fusion(GO:0090174)
0.1 2.7 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 3.2 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 8.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.5 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 10.6 GO:0006936 muscle contraction(GO:0006936)
0.1 0.6 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 1.9 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 1.2 GO:0035459 cargo loading into vesicle(GO:0035459)
0.1 4.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 4.1 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 0.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 7.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 21.5 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.1 1.5 GO:0060972 left/right pattern formation(GO:0060972)
0.1 2.5 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 3.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 2.2 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.7 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.2 GO:0060547 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 5.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 2.2 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 3.5 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.9 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 4.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.2 GO:0048675 axon extension(GO:0048675)
0.0 0.1 GO:0048640 negative regulation of developmental growth(GO:0048640)
0.0 0.8 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 2.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 12.1 GO:0099536 synaptic signaling(GO:0099536)
0.0 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.6 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.3 GO:0010138 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 4.1 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 2.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.0 GO:0016573 histone acetylation(GO:0016573)
0.0 0.3 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0032355 response to estradiol(GO:0032355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
17.0 102.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.9 46.9 GO:0044295 axonal growth cone(GO:0044295)
3.9 15.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
3.1 15.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
3.0 20.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
3.0 14.8 GO:0005883 neurofilament(GO:0005883)
2.4 19.3 GO:0033010 paranodal junction(GO:0033010)
2.2 19.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.1 12.4 GO:0005955 calcineurin complex(GO:0005955)
2.0 20.2 GO:0042583 chromaffin granule(GO:0042583)
2.0 20.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.0 5.9 GO:0033268 node of Ranvier(GO:0033268)
1.5 5.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
1.4 5.6 GO:0097524 sperm plasma membrane(GO:0097524)
1.2 4.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
1.0 4.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.9 8.3 GO:0089701 U2AF(GO:0089701)
0.9 14.3 GO:0031209 SCAR complex(GO:0031209)
0.9 6.9 GO:0034464 BBSome(GO:0034464)
0.9 112.4 GO:0043025 neuronal cell body(GO:0043025)
0.8 15.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.8 2.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.8 28.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.7 11.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.7 6.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.7 3.3 GO:0034657 GID complex(GO:0034657)
0.6 6.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.6 3.2 GO:0008091 spectrin(GO:0008091)
0.6 27.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.6 6.9 GO:0061617 MICOS complex(GO:0061617)
0.6 4.3 GO:0071818 BAT3 complex(GO:0071818)
0.6 5.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.6 50.4 GO:0005871 kinesin complex(GO:0005871)
0.6 2.4 GO:0060171 stereocilium membrane(GO:0060171)
0.6 17.2 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.6 4.5 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.5 17.4 GO:0030426 growth cone(GO:0030426)
0.5 1.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 2.4 GO:0005899 insulin receptor complex(GO:0005899)
0.5 3.7 GO:0072487 MSL complex(GO:0072487)
0.5 1.8 GO:0016589 NURF complex(GO:0016589)
0.5 2.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 3.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.4 5.8 GO:0000813 ESCRT I complex(GO:0000813)
0.4 3.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 1.2 GO:0031417 NatC complex(GO:0031417)
0.4 2.7 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.4 4.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 8.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 3.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 41.3 GO:0030425 dendrite(GO:0030425)
0.3 23.1 GO:0014069 postsynaptic density(GO:0014069)
0.3 3.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 26.2 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.3 6.1 GO:0035102 PRC1 complex(GO:0035102)
0.3 8.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 2.5 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 5.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 12.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 5.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 8.3 GO:0031201 SNARE complex(GO:0031201)
0.2 5.1 GO:0005921 gap junction(GO:0005921)
0.2 11.5 GO:0055037 recycling endosome(GO:0055037)
0.2 5.1 GO:0035371 microtubule plus-end(GO:0035371)
0.2 5.2 GO:0000421 autophagosome membrane(GO:0000421)
0.2 3.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 3.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.5 GO:0098842 postsynaptic early endosome(GO:0098842) postsynaptic endosome(GO:0098845)
0.2 68.1 GO:0043005 neuron projection(GO:0043005)
0.2 1.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 3.2 GO:0008278 cohesin complex(GO:0008278)
0.1 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 11.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.4 GO:0030120 vesicle coat(GO:0030120)
0.1 0.8 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 8.3 GO:0030133 transport vesicle(GO:0030133)
0.1 6.0 GO:0042383 sarcolemma(GO:0042383)
0.1 4.8 GO:0016342 catenin complex(GO:0016342)
0.1 6.0 GO:0001726 ruffle(GO:0001726)
0.1 2.2 GO:0000145 exocyst(GO:0000145)
0.1 3.3 GO:0030496 midbody(GO:0030496)
0.1 8.1 GO:0005882 intermediate filament(GO:0005882)
0.1 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 25.2 GO:0045202 synapse(GO:0045202)
0.1 2.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 7.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 1.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0005814 centriole(GO:0005814)
0.0 4.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 11.0 GO:0005768 endosome(GO:0005768)
0.0 2.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 16.4 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.6 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
4.1 12.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
3.9 15.6 GO:0097016 L27 domain binding(GO:0097016)
3.7 21.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
3.5 10.5 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
3.0 15.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
2.8 19.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
2.5 32.1 GO:0031628 opioid receptor binding(GO:0031628)
2.4 21.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
2.4 14.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.4 95.9 GO:0017075 syntaxin-1 binding(GO:0017075)
2.3 11.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
2.2 31.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.1 10.4 GO:0008046 axon guidance receptor activity(GO:0008046)
2.1 12.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
2.0 8.2 GO:0071889 14-3-3 protein binding(GO:0071889)
2.0 10.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
2.0 14.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
2.0 7.8 GO:0016842 amidine-lyase activity(GO:0016842)
1.6 14.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.5 23.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.5 41.1 GO:0017080 sodium channel regulator activity(GO:0017080)
1.5 11.9 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.4 17.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.3 20.0 GO:0051117 ATPase binding(GO:0051117)
1.2 17.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
1.2 40.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.2 23.6 GO:0003785 actin monomer binding(GO:0003785)
1.2 9.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
1.2 28.2 GO:0001540 beta-amyloid binding(GO:0001540)
1.1 29.6 GO:0042577 lipid phosphatase activity(GO:0042577)
1.1 5.6 GO:0008126 acetylesterase activity(GO:0008126)
1.1 12.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.1 5.4 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
1.1 25.7 GO:0031267 small GTPase binding(GO:0031267)
1.0 4.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.0 9.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.0 13.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.9 4.6 GO:0004127 cytidylate kinase activity(GO:0004127)
0.8 8.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.8 14.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.8 3.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.7 11.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.7 6.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.7 4.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.6 25.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.6 2.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.6 3.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.6 34.2 GO:0005178 integrin binding(GO:0005178)
0.6 3.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 14.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.5 9.9 GO:0005080 protein kinase C binding(GO:0005080)
0.5 8.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.5 26.2 GO:0008013 beta-catenin binding(GO:0008013)
0.5 33.2 GO:0051427 hormone receptor binding(GO:0051427)
0.5 2.5 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.5 3.9 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.5 2.4 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.5 19.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 4.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 4.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 4.3 GO:0070628 proteasome binding(GO:0070628)
0.4 5.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 15.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.4 8.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 42.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 6.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.4 8.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 1.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 11.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.4 2.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 12.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 17.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 10.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 1.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 4.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 4.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 4.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 20.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 3.7 GO:0043495 protein anchor(GO:0043495)
0.3 14.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 2.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.3 8.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.3 5.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 10.9 GO:0051087 chaperone binding(GO:0051087)
0.3 25.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.3 5.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 6.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 16.6 GO:0030276 clathrin binding(GO:0030276)
0.3 4.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 3.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 5.7 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 0.9 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 0.7 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 38.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 3.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 4.5 GO:0050811 GABA receptor binding(GO:0050811)
0.2 5.1 GO:0022829 wide pore channel activity(GO:0022829)
0.2 8.5 GO:0044325 ion channel binding(GO:0044325)
0.2 5.0 GO:0051018 protein kinase A binding(GO:0051018)
0.2 6.2 GO:0042287 MHC protein binding(GO:0042287)
0.2 0.6 GO:1901612 cardiolipin binding(GO:1901612)
0.2 9.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 3.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 14.0 GO:0043130 ubiquitin binding(GO:0043130)
0.2 3.6 GO:0070411 I-SMAD binding(GO:0070411)
0.2 2.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.2 0.7 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 9.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 13.3 GO:0045296 cadherin binding(GO:0045296)
0.1 56.3 GO:0015631 tubulin binding(GO:0015631)
0.1 15.2 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 11.3 GO:0003678 DNA helicase activity(GO:0003678)
0.1 1.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 3.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 7.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 3.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 5.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 23.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.3 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADPH binding(GO:0070402) NADH binding(GO:0070404)
0.1 11.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 7.8 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 6.1 GO:0051213 dioxygenase activity(GO:0051213)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.6 GO:0000149 SNARE binding(GO:0000149)
0.0 5.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.6 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 15.2 GO:0003924 GTPase activity(GO:0003924)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 20.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 2.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 10.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 20.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
1.1 23.3 PID REELIN PATHWAY Reelin signaling pathway
0.8 17.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.7 14.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.7 15.1 PID RHOA PATHWAY RhoA signaling pathway
0.6 6.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 8.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.5 15.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 9.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 3.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 5.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 4.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.2 12.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 4.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 3.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 5.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 4.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 6.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 6.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.3 PID AP1 PATHWAY AP-1 transcription factor network
0.1 5.0 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.2 PID CDC42 PATHWAY CDC42 signaling events
0.1 3.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
2.2 36.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.1 14.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.9 15.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.7 34.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.7 10.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.7 5.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 5.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.5 3.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.5 4.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 39.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.5 16.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 4.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 3.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4 5.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 5.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 5.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4 14.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 3.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 4.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 4.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 7.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 9.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 2.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 1.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 4.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 5.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 3.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 2.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 9.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 3.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 5.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 4.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 3.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 5.1 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import